| Year |
Citation |
Score |
| 2022 |
Riad MH, Park K, Ibañez-Tallon I, Heintz N. Local production of corticotropin-releasing hormone in prefrontal cortex modulates male-specific novelty exploration. Proceedings of the National Academy of Sciences of the United States of America. 119: e2211454119. PMID 36442105 DOI: 10.1073/pnas.2211454119 |
0.673 |
|
| 2022 |
Moya MV, Kim RD, Rao MN, Cotto BA, Pickett SB, Sferrazza CE, Heintz N, Schmidt EF. Unique molecular features and cellular responses differentiate two populations of motor cortical layer 5b neurons in a preclinical model of ALS. Cell Reports. 38: 110556. PMID 35320722 DOI: 10.1016/j.celrep.2022.110556 |
0.798 |
|
| 2022 |
Montalban E, Giralt A, Taing L, Schut EHS, Supiot LF, Castell L, Nakamura Y, de Pins B, Pelosi A, Goutebroze L, Tuduri P, Wang W, Neiburga KD, Vestito L, Castel J, ... ... Heintz N, et al. Translational profiling of mouse dopaminoceptive neurons reveals region-specific gene expression, exon usage, and striatal prostaglandin E2 modulatory effects. Molecular Psychiatry. PMID 35177825 DOI: 10.1038/s41380-022-01439-4 |
0.483 |
|
| 2021 |
Karayol R, Medrihan L, Warner-Schmidt JL, Fait BW, Rao MN, Holzner EB, Greengard P, Heintz N, Schmidt EF. Serotonin receptor 4 in the hippocampus modulates mood and anxiety. Molecular Psychiatry. PMID 33441982 DOI: 10.1038/s41380-020-00994-y |
0.622 |
|
| 2020 |
Shrestha P, Shan Z, Mamcarz M, Ruiz KSA, Zerihoun AT, Juan CY, Herrero-Vidal PM, Pelletier J, Heintz N, Klann E. Amygdala inhibitory neurons as loci for translation in emotional memories. Nature. PMID 33029009 DOI: 10.1038/s41586-020-2793-8 |
0.638 |
|
| 2020 |
Roussarie JP, Yao V, Rodriguez-Rodriguez P, Oughtred R, Rust J, Plautz Z, Kasturia S, Albornoz C, Wang W, Schmidt EF, Dannenfelser R, Tadych A, Brichta L, Barnea-Cramer A, Heintz N, et al. Selective Neuronal Vulnerability in Alzheimer's Disease: A Network-Based Analysis. Neuron. PMID 32603655 DOI: 10.1016/J.Neuron.2020.06.010 |
0.561 |
|
| 2020 |
Antolin-Fontes B, Li K, Ables JL, Riad MH, Görlich A, Williams M, Wang C, Lipford SM, Dao M, Liu J, Molina H, Heintz N, Kenny PJ, Ibañez-Tallon I. The habenular G-protein-coupled receptor 151 regulates synaptic plasticity and nicotine intake. Proceedings of the National Academy of Sciences of the United States of America. PMID 32098843 DOI: 10.1073/Pnas.1916132117 |
0.775 |
|
| 2020 |
Shrestha P, Ayata P, Herrero-Vidal P, Longo F, Gastone A, LeDoux JE, Heintz N, Klann E. Cell-type-specific drug-inducible protein synthesis inhibition demonstrates that memory consolidation requires rapid neuronal translation. Nature Neuroscience. PMID 31959934 DOI: 10.1038/S41593-019-0568-Z |
0.64 |
|
| 2019 |
Piccolo FM, Liu Z, Dong P, Hsu C, Stoyanova EI, Rao A, Tjian R, Heintz N. Author response: MeCP2 nuclear dynamics in live neurons results from low and high affinity chromatin interactions Elife. DOI: 10.7554/Elife.51449.Sa2 |
0.304 |
|
| 2018 |
Xu X, Stoyanova EI, Lemiesz AE, Xing J, Mash DC, Heintz N. Species and cell-type properties of classically defined human and rodent neurons and glia. Elife. 7. PMID 30320555 DOI: 10.7554/Elife.37551 |
0.307 |
|
| 2018 |
Mulvey B, Bhatti DL, Gyawali S, Lake AM, Kriaucionis S, Ford CP, Bruchas MR, Heintz N, Dougherty JD. Molecular and Functional Sex Differences of Noradrenergic Neurons in the Mouse Locus Coeruleus. Cell Reports. 23: 2225-2235. PMID 29791834 DOI: 10.1016/J.Celrep.2018.04.054 |
0.796 |
|
| 2018 |
Nakayama H, Ibañez-Tallon I, Heintz N. Cell-type specific contributions of medial prefrontal neurons to flexible behaviors. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 29650697 DOI: 10.1523/JNEUROSCI.3537-17.2018 |
0.695 |
|
| 2018 |
Xu X, Stoyanova EI, Lemiesz AE, Xing J, Mash DC, Heintz N. Author response: Species and cell-type properties of classically defined human and rodent neurons and glia Elife. DOI: 10.7554/Elife.37551.041 |
0.342 |
|
| 2017 |
Ables JL, Görlich A, Antolin-Fontes B, Wang C, Lipford SM, Riad MH, Ren J, Hu F, Luo M, Kenny PJ, Heintz N, Ibañez-Tallon I. Retrograde inhibition by a specific subset of interpeduncular α5 nicotinic neurons regulates nicotine preference. Proceedings of the National Academy of Sciences of the United States of America. PMID 29158387 DOI: 10.1073/Pnas.1717506114 |
0.774 |
|
| 2017 |
Mellén M, Ayata P, Heintz N. 5-hydroxymethylcytosine accumulation in postmitotic neurons results in functional demethylation of expressed genes. Proceedings of the National Academy of Sciences of the United States of America. PMID 28847947 DOI: 10.1073/pnas.1708044114 |
0.766 |
|
| 2017 |
Nectow AR, Moya MV, Ekstrand MI, Mousa A, McGuire KL, Sferrazza CE, Field BC, Rabinowitz GS, Sawicka K, Liang Y, Friedman JM, Heintz N, Schmidt EF. Rapid Molecular Profiling of Defined Cell Types Using Viral TRAP. Cell Reports. 19: 655-667. PMID 28423326 DOI: 10.1016/J.Celrep.2017.03.048 |
0.59 |
|
| 2016 |
Li K, Nakajima M, Ibañez-Tallon I, Heintz N. A Cortical Circuit for Sexually Dimorphic Oxytocin-Dependent Anxiety Behaviors. Cell. PMID 27641503 DOI: 10.1016/J.Cell.2016.08.067 |
0.72 |
|
| 2015 |
Miyoshi G, Young A, Petros T, Karayannis T, McKenzie Chang M, Lavado A, Iwano T, Nakajima M, Taniguchi H, Huang ZJ, Heintz N, Oliver G, Matsuzaki F, Machold RP, Fishell G. Prox1 Regulates the Subtype-Specific Development of Caudal Ganglionic Eminence-Derived GABAergic Cortical Interneurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 12869-89. PMID 26377473 DOI: 10.1523/Jneurosci.1164-15.2015 |
0.531 |
|
| 2015 |
Shrestha P, Mousa A, Heintz N. Layer 2/3 pyramidal cells in the medial prefrontal cortex moderate stress induced depressive behaviors. Elife. 4. PMID 26371510 DOI: 10.7554/Elife.08752 |
0.431 |
|
| 2015 |
Shrestha P, Mousa A, Heintz N. Author response: Layer 2/3 pyramidal cells in the medial prefrontal cortex moderate stress induced depressive behaviors Elife. DOI: 10.7554/Elife.08752.014 |
0.49 |
|
| 2014 |
Nakajima M, Görlich A, Heintz N. Oxytocin modulates female sociosexual behavior through a specific class of prefrontal cortical interneurons. Cell. 159: 295-305. PMID 25303526 DOI: 10.1016/J.Cell.2014.09.020 |
0.568 |
|
| 2014 |
McKnight NC, Zhong Y, Wold MS, Gong S, Phillips GR, Dou Z, Zhao Y, Heintz N, Zong WX, Yue Z. Beclin 1 is required for neuron viability and regulates endosome pathways via the UVRAG-VPS34 complex. Plos Genetics. 10: e1004626. PMID 25275521 DOI: 10.1371/Journal.Pgen.1004626 |
0.35 |
|
| 2014 |
Anthony TE, Dee N, Bernard A, Lerchner W, Heintz N, Anderson DJ. Control of stress-induced persistent anxiety by an extra-amygdala septohypothalamic circuit. Cell. 156: 522-36. PMID 24485458 DOI: 10.1016/J.Cell.2013.12.040 |
0.776 |
|
| 2013 |
Gerfen CR, Paletzki R, Heintz N. GENSAT BAC cre-recombinase driver lines to study the functional organization of cerebral cortical and basal ganglia circuits. Neuron. 80: 1368-83. PMID 24360541 DOI: 10.1016/j.neuron.2013.10.016 |
0.34 |
|
| 2013 |
Fishell G, Heintz N. The neuron identity problem: form meets function. Neuron. 80: 602-12. PMID 24183013 DOI: 10.1016/j.neuron.2013.10.035 |
0.404 |
|
| 2013 |
Rommel PC, Bosque D, Gitlin AD, Croft GF, Heintz N, Casellas R, Nussenzweig MC, Kriaucionis S, Robbiani DF. Fate mapping for activation-induced cytidine deaminase (AID) marks non-lymphoid cells during mouse development. Plos One. 8: e69208. PMID 23861962 DOI: 10.1371/Journal.Pone.0069208 |
0.399 |
|
| 2013 |
Lanoue V, Usardi A, Sigoillot SM, Talleur M, Iyer K, Mariani J, Isope P, Vodjdani G, Heintz N, Selimi F. The adhesion-GPCR BAI3, a gene linked to psychiatric disorders, regulates dendrite morphogenesis in neurons. Molecular Psychiatry. 18: 943-50. PMID 23628982 DOI: 10.1038/Mp.2013.46 |
0.412 |
|
| 2013 |
Schmidt EF, Kus L, Gong S, Heintz N. BAC transgenic mice and the GENSAT database of engineered mouse strains. Cold Spring Harbor Protocols. 2013. PMID 23457350 DOI: 10.1101/pdb.top073692 |
0.633 |
|
| 2013 |
Dalal J, Roh JH, Maloney SE, Akuffo A, Shah S, Yuan H, Wamsley B, Jones WB, de Guzman Strong C, Gray PA, Holtzman DM, Heintz N, Dougherty JD. Translational profiling of hypocretin neurons identifies candidate molecules for sleep regulation. Genes & Development. 27: 565-78. PMID 23431030 DOI: 10.1101/Gad.207654.112 |
0.637 |
|
| 2013 |
Dougherty JD, Maloney SE, Wozniak DF, Rieger MA, Sonnenblick L, Coppola G, Mahieu NG, Zhang J, Cai J, Patti GJ, Abrahams BS, Geschwind DH, Heintz N. The disruption of Celf6, a gene identified by translational profiling of serotonergic neurons, results in autism-related behaviors. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 2732-53. PMID 23407934 DOI: 10.1523/Jneurosci.4762-12.2013 |
0.684 |
|
| 2012 |
Mellén M, Ayata P, Dewell S, Kriaucionis S, Heintz N. MeCP2 binds to 5hmC enriched within active genes and accessible chromatin in the nervous system. Cell. 151: 1417-30. PMID 23260135 DOI: 10.1016/J.Cell.2012.11.022 |
0.398 |
|
| 2012 |
Dougherty JD, Zhang J, Feng H, Gong S, Heintz N. Mouse transgenesis in a single locus with independent regulation for multiple fluorophores. Plos One. 7: e40511. PMID 22808177 DOI: 10.1371/Journal.Pone.0040511 |
0.604 |
|
| 2012 |
Heller EA, Zhang W, Selimi F, Earnheart JC, ?limak MA, Santos-Torres J, Ibañez-Tallon I, Aoki C, Chait BT, Heintz N. The biochemical anatomy of cortical inhibitory synapses. Plos One. 7: e39572. PMID 22768092 DOI: 10.1371/Journal.Pone.0039572 |
0.729 |
|
| 2012 |
Chan CS, Peterson JD, Gertler TS, Glajch KE, Quintana RE, Cui Q, Sebel LE, Plotkin JL, Shen W, Heiman M, Heintz N, Greengard P, Surmeier DJ. Strain-specific regulation of striatal phenotype in Drd2-eGFP BAC transgenic mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 9124-32. PMID 22764222 DOI: 10.1523/Jneurosci.0229-12.2012 |
0.314 |
|
| 2012 |
Warner-Schmidt JL, Schmidt EF, Marshall JJ, Rubin AJ, Arango-Lievano M, Kaplitt MG, Ibañez-Tallon I, Heintz N, Greengard P. Cholinergic interneurons in the nucleus accumbens regulate depression-like behavior. Proceedings of the National Academy of Sciences of the United States of America. 109: 11360-5. PMID 22733786 DOI: 10.1073/Pnas.1209293109 |
0.769 |
|
| 2012 |
Tien AC, Tsai HH, Molofsky AV, McMahon M, Foo LC, Kaul A, Dougherty JD, Heintz N, Gutmann DH, Barres BA, Rowitch DH. Regulated temporal-spatial astrocyte precursor cell proliferation involves BRAF signalling in mammalian spinal cord. Development (Cambridge, England). 139: 2477-87. PMID 22675209 DOI: 10.1242/Jcs.116657 |
0.516 |
|
| 2012 |
Schmidt EF, Warner-Schmidt JL, Otopalik BG, Pickett SB, Greengard P, Heintz N. Identification of the cortical neurons that mediate antidepressant responses. Cell. 149: 1152-63. PMID 22632977 DOI: 10.1016/J.Cell.2012.03.038 |
0.791 |
|
| 2012 |
Walker BA, Hengst U, Kim HJ, Jeon NL, Schmidt EF, Heintz N, Milner TA, Jaffrey SR. Reprogramming axonal behavior by axon-specific viral transduction. Gene Therapy. 19: 947-55. PMID 22278412 DOI: 10.1038/Gt.2011.217 |
0.548 |
|
| 2012 |
Tien AC, Tsai HH, Molofsky AV, McMahon M, Foo LC, Kaul A, Dougherty JD, Heintz N, Gutmann DH, Barres BA, Rowitch DH. Regulated temporal-spatial astrocyte precursor cell proliferation involves BRAF signalling in mammalian spinal cord Journal of Cell Science. 125: 2477-2487. |
0.476 |
|
| 2010 |
Morishita H, Miwa JM, Heintz N, Hensch TK. Lynx1, a cholinergic brake, limits plasticity in adult visual cortex. Science (New York, N.Y.). 330: 1238-40. PMID 21071629 DOI: 10.1126/Science.1195320 |
0.7 |
|
| 2010 |
Chao HT, Chen H, Samaco RC, Xue M, Chahrour M, Yoo J, Neul JL, Gong S, Lu HC, Heintz N, Ekker M, Rubenstein JL, Noebels JL, Rosenmund C, Zoghbi HY. Dysfunction in GABA signalling mediates autism-like stereotypies and Rett syndrome phenotypes. Nature. 468: 263-9. PMID 21068835 DOI: 10.1038/Nature09582 |
0.329 |
|
| 2010 |
Gong S, Kus L, Heintz N. Rapid bacterial artificial chromosome modification for large-scale mouse transgenesis. Nature Protocols. 5: 1678-96. PMID 20885380 DOI: 10.1038/nprot.2010.131 |
0.318 |
|
| 2010 |
Dougherty JD, Schmidt EF, Nakajima M, Heintz N. Analytical approaches to RNA profiling data for the identification of genes enriched in specific cells. Nucleic Acids Research. 38: 4218-30. PMID 20308160 DOI: 10.1093/Nar/Gkq130 |
0.758 |
|
| 2010 |
Groh A, Meyer HS, Schmidt EF, Heintz N, Sakmann B, Krieger P. Cell-type specific properties of pyramidal neurons in neocortex underlying a layout that is modifiable depending on the cortical area. Cerebral Cortex (New York, N.Y. : 1991). 20: 826-36. PMID 19643810 DOI: 10.1093/Cercor/Bhp152 |
0.575 |
|
| 2009 |
Siegert S, Scherf BG, Del Punta K, Didkovsky N, Heintz N, Roska B. Genetic address book for retinal cell types. Nature Neuroscience. 12: 1197-204. PMID 19648912 DOI: 10.1038/nn.2370 |
0.39 |
|
| 2009 |
Selimi F, Cristea IM, Heller E, Chait BT, Heintz N. Proteomic studies of a single CNS synapse type: the parallel fiber/purkinje cell synapse. Plos Biology. 7: e83. PMID 19402746 DOI: 10.1371/Journal.Pbio.1000083 |
0.543 |
|
| 2009 |
Kriaucionis S, Heintz N. The nuclear DNA base 5-hydroxymethylcytosine is present in Purkinje neurons and the brain. Science (New York, N.Y.). 324: 929-30. PMID 19372393 DOI: 10.1126/science.1169786 |
0.383 |
|
| 2009 |
Tekinay AB, Nong Y, Miwa JM, Lieberam I, Ibanez-Tallon I, Greengard P, Heintz N. A role for LYNX2 in anxiety-related behavior. Proceedings of the National Academy of Sciences of the United States of America. 106: 4477-82. PMID 19246390 DOI: 10.1073/Pnas.0813109106 |
0.781 |
|
| 2009 |
Doyle JP, Dougherty JD, Heiman M, Schmidt EF, Stevens TR, Ma G, Bupp S, Shrestha P, Shah RD, Doughty ML, Gong S, Greengard P, Heintz N. Application of a Translational Profiling Approach for the Comparative Analysis of CNS Cell Types (DOI:10.1016/j.cell.2008.10.029) Cell. 139: 1022. DOI: 10.1016/j.cell.2009.11.011 |
0.772 |
|
| 2008 |
Chadman KK, Gong S, Scattoni ML, Boltuck SE, Gandhy SU, Heintz N, Crawley JN. Minimal aberrant behavioral phenotypes of neuroligin-3 R451C knockin mice. Autism Research : Official Journal of the International Society For Autism Research. 1: 147-58. PMID 19360662 DOI: 10.1002/Aur.22 |
0.308 |
|
| 2008 |
Doyle JP, Dougherty JD, Heiman M, Schmidt EF, Stevens TR, Ma G, Bupp S, Shrestha P, Shah RD, Doughty ML, Gong S, Greengard P, Heintz N. Application of a translational profiling approach for the comparative analysis of CNS cell types. Cell. 135: 749-62. PMID 19013282 DOI: 10.1016/J.Cell.2008.10.029 |
0.784 |
|
| 2008 |
Heiman M, Schaefer A, Gong S, Peterson JD, Day M, Ramsey KE, Suárez-Fariñas M, Schwarz C, Stephan DA, Surmeier DJ, Greengard P, Heintz N. A translational profiling approach for the molecular characterization of CNS cell types. Cell. 135: 738-48. PMID 19013281 DOI: 10.1016/J.Cell.2008.10.028 |
0.422 |
|
| 2008 |
Anthony TE, Heintz N. Genetic lineage tracing defines distinct neurogenic and gliogenic stages of ventral telencephalic radial glial development. Neural Development. 3: 30. PMID 18986511 DOI: 10.1186/1749-8104-3-30 |
0.744 |
|
| 2008 |
Drenan RM, Grady SR, Whiteaker P, McClure-Begley T, McKinney S, Miwa JM, Bupp S, Heintz N, McIntosh JM, Bencherif M, Marks MJ, Lester HA. In vivo activation of midbrain dopamine neurons via sensitized, high-affinity alpha 6 nicotinic acetylcholine receptors. Neuron. 60: 123-36. PMID 18940593 DOI: 10.1016/J.Neuron.2008.09.009 |
0.7 |
|
| 2008 |
Nishi A, Kuroiwa M, Miller DB, O'Callaghan JP, Bateup HS, Shuto T, Sotogaku N, Fukuda T, Heintz N, Greengard P, Snyder GL. Distinct roles of PDE4 and PDE10A in the regulation of cAMP/PKA signaling in the striatum. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 10460-71. PMID 18923023 DOI: 10.1523/Jneurosci.2518-08.2008 |
0.317 |
|
| 2008 |
Bateup HS, Svenningsson P, Kuroiwa M, Gong S, Nishi A, Heintz N, Greengard P. Cell type-specific regulation of DARPP-32 phosphorylation by psychostimulant and antipsychotic drugs. Nature Neuroscience. 11: 932-9. PMID 18622401 DOI: 10.1038/Nn.2153 |
0.344 |
|
| 2007 |
Gong S, Doughty M, Harbaugh CR, Cummins A, Hatten ME, Heintz N, Gerfen CR. Targeting Cre recombinase to specific neuron populations with bacterial artificial chromosome constructs. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 9817-23. PMID 17855595 DOI: 10.1523/JNEUROSCI.2707-07.2007 |
0.365 |
|
| 2007 |
Gorokhova S, Bibert S, Geering K, Heintz N. A novel family of transmembrane proteins interacting with beta subunits of the Na,K-ATPase. Human Molecular Genetics. 16: 2394-410. PMID 17606467 DOI: 10.1093/Hmg/Ddm167 |
0.64 |
|
| 2007 |
Head K, Gong S, Joseph S, Wang C, Burkhardt T, Rossi MR, LaDuca J, Matsui S, Vaughan M, Hicks DG, Heintz N, Cowell JK. Defining the expression pattern of the LGI1 gene in BAC transgenic mice. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 18: 328-37. PMID 17565425 DOI: 10.1007/s00335-007-9024-6 |
0.367 |
|
| 2007 |
Chang SY, Zagha E, Kwon ES, Ozaita A, Bobik M, Martone ME, Ellisman MH, Heintz N, Rudy B. Distribution of Kv3.3 potassium channel subunits in distinct neuronal populations of mouse brain. The Journal of Comparative Neurology. 502: 953-72. PMID 17444489 DOI: 10.1002/Cne.21353 |
0.398 |
|
| 2007 |
Anthony TE, Heintz N. The folate metabolic enzyme ALDH1L1 is restricted to the midline of the early CNS, suggesting a role in human neural tube defects. The Journal of Comparative Neurology. 500: 368-83. PMID 17111379 DOI: 10.1002/Cne.21179 |
0.748 |
|
| 2007 |
Heintz N, Hatten ME, Gong S, Myriam H, Schaefer A, Doyle J, Stevens T, Dougherty J, Greengard P. Molecular definition of CNS cell types and their physiologic responses in health and disease. The Faseb Journal. 21. DOI: 10.1096/fasebj.21.5.a201-c |
0.745 |
|
| 2006 |
Miwa JM, Stevens TR, King SL, Caldarone BJ, Ibanez-Tallon I, Xiao C, Fitzsimonds RM, Pavlides C, Lester HA, Picciotto MR, Heintz N. The prototoxin lynx1 acts on nicotinic acetylcholine receptors to balance neuronal activity and survival in vivo. Neuron. 51: 587-600. PMID 16950157 DOI: 10.1016/J.Neuron.2006.07.025 |
0.77 |
|
| 2006 |
Yang Z, Jiang H, Chaichanasakul T, Chachainasakul T, Gong S, Yang XW, Heintz N, Lin S. Modified bacterial artificial chromosomes for zebrafish transgenesis. Methods (San Diego, Calif.). 39: 183-8. PMID 16828309 DOI: 10.1016/j.ymeth.2006.04.011 |
0.35 |
|
| 2005 |
Rubinsztein DC, DiFiglia M, Heintz N, Nixon RA, Qin ZH, Ravikumar B, Stefanis L, Tolkovsky A. Autophagy and its possible roles in nervous system diseases, damage and repair. Autophagy. 1: 11-22. PMID 16874045 DOI: 10.4161/Auto.1.1.1513 |
0.304 |
|
| 2005 |
Selimi F, Heintz N. How neurons keep in touch. Nature Neuroscience. 8: 1417-8. PMID 16251974 DOI: 10.1038/nn1105-1417 |
0.343 |
|
| 2005 |
Hatten ME, Heintz N. Large-scale genomic approaches to brain development and circuitry. Annual Review of Neuroscience. 28: 89-108. PMID 16022591 DOI: 10.1146/annurev.neuro.26.041002.131436 |
0.341 |
|
| 2005 |
Gu X, Li C, Wei W, Lo V, Gong S, Li SH, Iwasato T, Itohara S, Li XJ, Mody I, Heintz N, Yang XW. Pathological cell-cell interactions elicited by a neuropathogenic form of mutant Huntingtin contribute to cortical pathogenesis in HD mice. Neuron. 46: 433-44. PMID 15882643 DOI: 10.1016/J.Neuron.2005.03.025 |
0.443 |
|
| 2005 |
Anthony TE, Heintz N. Cre-ating somatic cell genetic mosaics in the mouse. Cell. 121: 322-3. PMID 15882615 DOI: 10.1016/J.Cell.2005.04.019 |
0.755 |
|
| 2005 |
Anthony TE, Mason HA, Gridley T, Fishell G, Heintz N. Brain lipid-binding protein is a direct target of Notch signaling in radial glial cells. Genes & Development. 19: 1028-33. PMID 15879553 DOI: 10.1101/Gad.1302105 |
0.769 |
|
| 2004 |
Austin CP, Battey JF, Bradley A, Bucan M, Capecchi M, Collins FS, Dove WF, Duyk G, Dymecki S, Eppig JT, Grieder FB, Heintz N, Hicks G, Insel TR, Joyner A, et al. The knockout mouse project. Nature Genetics. 36: 921-4. PMID 15340423 DOI: 10.1038/Ng0904-921 |
0.303 |
|
| 2004 |
Ibañez-Tallon I, Wen H, Miwa JM, Xing J, Tekinay AB, Ono F, Brehm P, Heintz N. Tethering naturally occurring peptide toxins for cell-autonomous modulation of ion channels and receptors in vivo. Neuron. 43: 305-11. PMID 15294139 DOI: 10.1016/J.Neuron.2004.07.015 |
0.775 |
|
| 2004 |
Ibañez-Tallon I, Pagenstecher A, Fliegauf M, Olbrich H, Kispert A, Ketelsen UP, North A, Heintz N, Omran H. Dysfunction of axonemal dynein heavy chain Mdnah5 inhibits ependymal flow and reveals a novel mechanism for hydrocephalus formation. Human Molecular Genetics. 13: 2133-41. PMID 15269178 DOI: 10.1093/Hmg/Ddh219 |
0.308 |
|
| 2004 |
Heintz N. Gene expression nervous system atlas (GENSAT). Nature Neuroscience. 7: 483. PMID 15114362 DOI: 10.1038/nn0504-483 |
0.307 |
|
| 2004 |
Anthony TE, Klein C, Fishell G, Heintz N. Radial glia serve as neuronal progenitors in all regions of the central nervous system. Neuron. 41: 881-90. PMID 15046721 DOI: 10.1016/S0896-6273(04)00140-0 |
0.759 |
|
| 2003 |
Yue Z, Jin S, Yang C, Levine AJ, Heintz N. Beclin 1, an autophagy gene essential for early embryonic development, is a haploinsufficient tumor suppressor. Proceedings of the National Academy of Sciences of the United States of America. 100: 15077-82. PMID 14657337 DOI: 10.1073/Pnas.2436255100 |
0.303 |
|
| 2003 |
Gong S, Zheng C, Doughty ML, Losos K, Didkovsky N, Schambra UB, Nowak NJ, Joyner A, Leblanc G, Hatten ME, Heintz N. A gene expression atlas of the central nervous system based on bacterial artificial chromosomes. Nature. 425: 917-25. PMID 14586460 DOI: 10.1038/nature02033 |
0.369 |
|
| 2002 |
Gong S, Yang XW, Li C, Heintz N. Highly efficient modification of bacterial artificial chromosomes (BACs) using novel shuttle vectors containing the R6Kgamma origin of replication. Genome Research. 12: 1992-8. PMID 12466304 DOI: 10.1101/Gr.476202 |
0.349 |
|
| 2002 |
Yue Z, Horton A, Bravin M, DeJager PL, Selimi F, Heintz N. A novel protein complex linking the delta 2 glutamate receptor and autophagy: implications for neurodegeneration in lurcher mice. Neuron. 35: 921-33. PMID 12372286 DOI: 10.1016/S0896-6273(02)00861-9 |
0.337 |
|
| 2002 |
Ibañez-Tallon I, Gorokhova S, Heintz N. Loss of function of axonemal dynein Mdnah5 causes primary ciliary dyskinesia and hydrocephalus. Human Molecular Genetics. 11: 715-21. PMID 11912187 DOI: 10.1093/Hmg/11.6.715 |
0.616 |
|
| 2002 |
Ibañez-Tallon I, Miwa JM, Wang HL, Adams NC, Crabtree GW, Sine SM, Heintz N. Novel modulation of neuronal nicotinic acetylcholine receptors by association with the endogenous prototoxin lynx1. Neuron. 33: 893-903. PMID 11906696 DOI: 10.1016/S0896-6273(02)00632-3 |
0.717 |
|
| 2001 |
Heintz N. BAC to the future: the use of bac transgenic mice for neuroscience research. Nature Reviews. Neuroscience. 2: 861-70. PMID 11733793 DOI: 10.1038/35104049 |
0.316 |
|
| 2001 |
Misulovin Z, Yang XW, Yu W, Heintz N, Meffre E. A rapid method for targeted modification and screening of recombinant bacterial artificial chromosome. Journal of Immunological Methods. 257: 99-105. PMID 11687243 DOI: 10.1016/S0022-1759(01)00452-5 |
0.323 |
|
| 2000 |
Heintz N. One-hit neuronal death. Nature. 406: 137, 139. PMID 10910338 DOI: 10.1038/35018196 |
0.323 |
|
| 2000 |
Heintz N, Zoghbi HY. Insights from mouse models into the molecular basis of neurodegeneration. Annual Review of Physiology. 62: 779-802. PMID 10845111 DOI: 10.1146/annurev.physiol.62.1.779 |
0.335 |
|
| 2000 |
Doughty ML, De Jager PL, Korsmeyer SJ, Heintz N. Neurodegeneration in Lurcher mice occurs via multiple cell death pathways. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 20: 3687-94. PMID 10804210 DOI: 10.1523/Jneurosci.20-10-03687.2000 |
0.337 |
|
| 2000 |
Heintz N. Analysis of mammalian central nervous system gene expression and function using bacterial artificial chromosome-mediated transgenesis. Human Molecular Genetics. 9: 937-43. PMID 10767317 DOI: 10.1093/Hmg/9.6.937 |
0.388 |
|
| 1999 |
Yang XW, Wynder C, Doughty ML, Heintz N. BAC-mediated gene-dosage analysis reveals a role for Zipro1 (Ru49/Zfp38) in progenitor cell proliferation in cerebellum and skin. Nature Genetics. 22: 327-35. PMID 10431235 DOI: 10.1038/11896 |
0.417 |
|
| 1999 |
Heintz N, De Jager PL. GluR delta 2 and the development and death of cerebellar Purkinje neurons in lurcher mice. Annals of the New York Academy of Sciences. 868: 502-14. PMID 10414327 DOI: 10.1111/j.1749-6632.1999.tb11319.x |
0.4 |
|
| 1999 |
Miwa JM, Ibanez-Tallon I, Crabtree GW, Sánchez R, Sali A, Role LW, Heintz N. lynx1, an endogenous toxin-like modulator of nicotinic acetylcholine receptors in the mammalian CNS. Neuron. 23: 105-14. PMID 10402197 DOI: 10.1016/S0896-6273(00)80757-6 |
0.808 |
|
| 1998 |
De Jager PL, Heintz N. The lurcher mutation and ionotropic glutamate receptors: contributions to programmed neuronal death in vivo. Brain Pathology (Zurich, Switzerland). 8: 795-807. PMID 9804384 DOI: 10.1111/J.1750-3639.1998.Tb00201.X |
0.373 |
|
| 1998 |
Gubbay J, Doyle JP, Skinner M, Heintz N. Changing patterns of gene expression identify multiple steps during regression of rat prostate in vivo. Endocrinology. 139: 2935-43. PMID 9607804 DOI: 10.1210/Endo.139.6.6075 |
0.306 |
|
| 1997 |
Yang XW, Model P, Heintz N. Homologous recombination based modification in Escherichia coli and germline transmission in transgenic mice of a bacterial artificial chromosome. Nature Biotechnology. 15: 859-65. PMID 9306400 DOI: 10.1038/Nbt0997-859 |
0.351 |
|
| 1997 |
Rousselot P, Heintz N, Nottebohm F. Expression of brain lipid binding protein in the brain of the adult canary and its implications for adult neurogenesis. The Journal of Comparative Neurology. 385: 415-26. PMID 9300768 DOI: 10.1002/(SICI)1096-9861(19970901)385:3<415::AID-CNE6>3.0.CO;2-6 |
0.31 |
|
| 1997 |
Zuo J, De Jager PL, Takahashi KA, Jiang W, Linden DJ, Heintz N. Neurodegeneration in Lurcher mice caused by mutation in delta2 glutamate receptor gene. Nature. 388: 769-73. PMID 9285588 DOI: 10.1038/42009 |
0.383 |
|
| 1997 |
Arnold DB, Heintz N. A calcium responsive element that regulates expression of two calcium binding proteins in Purkinje cells. Proceedings of the National Academy of Sciences of the United States of America. 94: 8842-7. PMID 9238065 DOI: 10.1073/pnas.94.16.8842 |
0.345 |
|
| 1997 |
Cheng SS, Heintz N. Massive loss of mid- and hindbrain neurons during embryonic development of homozygous lurcher mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 17: 2400-7. PMID 9065501 DOI: 10.1523/Jneurosci.17-07-02400.1997 |
0.374 |
|
| 1997 |
Hatten ME, Alder J, Zimmerman K, Heintz N. Genes involved in cerebellar cell specification and differentiation. Current Opinion in Neurobiology. 7: 40-7. PMID 9039803 DOI: 10.1016/S0959-4388(97)80118-3 |
0.368 |
|
| 1996 |
Segil N, Guermah M, Hoffmann A, Roeder RG, Heintz N. Mitotic regulation of TFIID: inhibition of activator-dependent transcription and changes in subcellular localization. Genes & Development. 10: 2389-400. PMID 8843192 DOI: 10.1101/Gad.10.19.2389 |
0.614 |
|
| 1996 |
Heintz N. Ataxia telangiectasia: cell signaling, cell death and the cell cycle. Current Opinion in Neurology. 9: 137-40. PMID 8782982 DOI: 10.1097/00019052-199604000-00014 |
0.333 |
|
| 1996 |
Yang XW, Zhong R, Heintz N. Granule cell specification in the developing mouse brain as defined by expression of the zinc finger transcription factor RU49. Development (Cambridge, England). 122: 555-66. PMID 8625807 |
0.368 |
|
| 1996 |
Zheng C, Heintz N, Hatten ME. CNS gene encoding astrotactin, which supports neuronal migration along glial fibers. Science (New York, N.Y.). 272: 417-9. PMID 8602532 DOI: 10.1126/Science.272.5260.417 |
0.385 |
|
| 1995 |
Zuo J, De Jager PL, Norman DJ, Heintz N. Generation of a high-resolution genetic map and a YAC contig of the Lurcher locus on mouse chromosome 6. Genome Research. 5: 381-92. PMID 8750197 DOI: 10.1101/Gr.5.4.381 |
0.312 |
|
| 1995 |
Hatten ME, Heintz N. Mechanisms of neural patterning and specification in the developing cerebellum. Annual Review of Neuroscience. 18: 385-408. PMID 7605067 DOI: 10.1146/annurev.ne.18.030195.002125 |
0.388 |
|
| 1995 |
Feng L, Heintz N. Differentiating neurons activate transcription of the brain lipid-binding protein gene in radial glia through a novel regulatory element. Development (Cambridge, England). 121: 1719-30. PMID 7600988 |
0.313 |
|
| 1994 |
Feng L, Hatten ME, Heintz N. Brain lipid-binding protein (BLBP): a novel signaling system in the developing mammalian CNS. Neuron. 12: 895-908. PMID 8161459 DOI: 10.1016/0896-6273(94)90341-7 |
0.381 |
|
| 1994 |
Martinelli R, Heintz N. H1TF2A, the large subunit of a heterodimeric, glutamine-rich CCAAT-binding transcription factor involved in histone H1 cell cycle regulation. Molecular and Cellular Biology. 14: 8322-32. PMID 7969168 DOI: 10.1128/Mcb.14.12.8322 |
0.325 |
|
| 1994 |
Arnold D, Feng L, Kim J, Heintz N. A strategy for the analysis of gene expression during neural development. Proceedings of the National Academy of Sciences of the United States of America. 91: 9970-4. PMID 7937928 DOI: 10.1073/pnas.91.21.9970 |
0.59 |
|
| 1994 |
Baird DH, Hatten ME, Heintz N, Mason CA. Micromethods for Analyzing Axon-Target Interactions in Vitro Neuroprotocols. 4: 106-115. DOI: 10.1006/ncmn.1994.1013 |
0.307 |
|
| 1993 |
McKinney JD, Chang F, Heintz N, Cross FR. Negative regulation of FAR1 at the Start of the yeast cell cycle. Genes & Development. 7: 833-43. PMID 8491380 DOI: 10.1101/Gad.7.5.833 |
0.327 |
|
| 1991 |
Gao WO, Heintz N, Hatten ME. Cerebellar granule cell neurogenesis is regulated by cell-cell interactions in vitro. Neuron. 6: 705-15. PMID 2025426 DOI: 10.1016/0896-6273(91)90168-Y |
0.381 |
|
| 1991 |
Heintz N. The regulation of histone gene expression during the cell cycle. Biochimica Et Biophysica Acta. 1088: 327-39. PMID 2015297 DOI: 10.1016/0167-4781(91)90122-3 |
0.317 |
|
| 1991 |
La Bella F, Heintz N. Histone gene transcription factor binding in extracts of normal human cells. Molecular and Cellular Biology. 11: 5825-31. PMID 1944265 DOI: 10.1128/Mcb.11.12.5825 |
0.338 |
|
| 1991 |
Roberts SB, Segil N, Heintz N. Differential phosphorylation of the transcription factor Oct1 during the cell cycle. Science (New York, N.Y.). 253: 1022-6. PMID 1887216 DOI: 10.1126/Science.1887216 |
0.328 |
|
| 1991 |
McKinney JD, Heintz N. Transcriptional regulation in the eukaryotic cell cycle. Trends in Biochemical Sciences. 16: 430-5. PMID 1776174 DOI: 10.1016/0968-0004(91)90170-Z |
0.325 |
|
| 1991 |
Segil N, Roberts SB, Heintz N. Mitotic phosphorylation of the Oct-1 homeodomain and regulation of Oct-1 DNA binding activity. Science (New York, N.Y.). 254: 1814-6. PMID 1684878 DOI: 10.1126/Science.1684878 |
0.312 |
|
| 1990 |
Ross ME, Fletcher C, Mason CA, Hatten ME, Heintz N. Meander tail reveals a discrete developmental unit in the mouse cerebellum. Proceedings of the National Academy of Sciences of the United States of America. 87: 4189-92. PMID 2349228 DOI: 10.1073/pnas.87.11.4189 |
0.349 |
|
| 1989 |
Gallinari P, La Bella F, Heintz N. Characterization and purification of H1TF2, a novel CCAAT-binding protein that interacts with a histone H1 subtype-specific consensus element. Molecular and Cellular Biology. 9: 1566-75. PMID 2725515 DOI: 10.1128/Mcb.9.4.1566 |
0.313 |
|
| 1989 |
La Bella F, Gallinari P, McKinney J, Heintz N. Histone H1 subtype-specific consensus elements mediate cell cycle-regulated transcription in vitro. Genes & Development. 3: 1982-90. PMID 2620829 DOI: 10.1101/Gad.3.12A.1982 |
0.319 |
|
| 1988 |
O'Neill EA, Fletcher C, Burrow CR, Heintz N, Roeder RG, Kelly TJ. Transcription factor OTF-1 is functionally identical to the DNA replication factor NF-III. Science (New York, N.Y.). 241: 1210-3. PMID 3413485 DOI: 10.1126/Science.3413485 |
0.446 |
|
| 1988 |
LaBella F, Sive HL, Roeder RG, Heintz N. Cell-cycle regulation of a human histone H2b gene is mediated by the H2b subtype-specific consensus element. Genes & Development. 2: 32-9. PMID 3128460 DOI: 10.1101/Gad.2.1.32 |
0.662 |
|
| 1988 |
Dailey L, Roberts SB, Heintz N. Purification of the human histone H4 gene-specific transcription factors H4TF-1 and H4TF-2. Genes & Development. 2: 1700-12. PMID 3071490 DOI: 10.1101/Gad.2.12B.1700 |
0.33 |
|
| 1987 |
Fletcher C, Heintz N, Roeder RG. Purification and characterization of OTF-1, a transcription factor regulating cell cycle expression of a human histone H2b gene. Cell. 51: 773-81. PMID 3677172 DOI: 10.1016/0092-8674(87)90100-0 |
0.484 |
|
| 1987 |
Simon MC, Kitchener K, Kao HT, Hickey E, Weber L, Voellmy R, Heintz N, Nevins JR. Selective induction of human heat shock gene transcription by the adenovirus E1A gene products, including the 12S E1A product. Molecular and Cellular Biology. 7: 2884-90. PMID 2959854 DOI: 10.1128/Mcb.7.8.2884 |
0.316 |
|
| 1986 |
Dailey L, Hanly SM, Roeder RG, Heintz N. Distinct transcription factors bind specifically to two regions of the human histone H4 promoter. Proceedings of the National Academy of Sciences of the United States of America. 83: 7241-5. PMID 3463962 DOI: 10.1073/Pnas.83.19.7241 |
0.475 |
|
| 1986 |
Sive HL, Heintz N, Roeder RG. Multiple sequence elements are required for maximal in vitro transcription of a human histone H2B gene. Molecular and Cellular Biology. 6: 3329-40. PMID 3025588 DOI: 10.1128/mcb.6.10.3329-3340.1986 |
0.654 |
|
| 1985 |
Kao HT, Capasso O, Heintz N, Nevins JR. Cell cycle control of the human HSP70 gene: implications for the role of a cellular E1A-like function. Molecular and Cellular Biology. 5: 628-33. PMID 3872994 DOI: 10.1128/MCB.5.4.628 |
0.341 |
|
| 1985 |
Capasso O, Heintz N. Regulated expression of mammalian histone H4 genes in vivo requires a trans-acting transcription factor. Proceedings of the National Academy of Sciences of the United States of America. 82: 5622-6. PMID 3862085 DOI: 10.1073/Pnas.82.17.5622 |
0.349 |
|
| 1984 |
Heintz N, Roeder RG. Transcription of human histone genes in extracts from synchronized HeLa cells. Proceedings of the National Academy of Sciences of the United States of America. 81: 2713-7. PMID 6585823 |
0.424 |
|
| 1984 |
Sive HL, Heintz N, Roeder RG. Regulation of human histone gene expression during the HeLa cell cycle requires protein synthesis. Molecular and Cellular Biology. 4: 2723-34. PMID 6441888 DOI: 10.1128/mcb.4.12.2723-2734.1984 |
0.662 |
|
| 1983 |
Zhong R, Roeder RG, Heintz N. The primary structure and expression of four cloned human histone genes. Nucleic Acids Research. 11: 7409-25. PMID 6647026 DOI: 10.1093/nar/11.21.7409 |
0.477 |
|
| 1983 |
Strayer D, Heintz N, Roeder R, Gillespie D. Three organizations of human DNA. Proceedings of the National Academy of Sciences of the United States of America. 80: 4770-4. PMID 6576359 DOI: 10.1073/PNAS.80.15.4770 |
0.342 |
|
| 1983 |
Heintz N, Sive HL, Roeder RG. Regulation of human histone gene expression: kinetics of accumulation and changes in the rate of synthesis and in the half-lives of individual histone mRNAs during the HeLa cell cycle. Molecular and Cellular Biology. 3: 539-50. PMID 6406835 DOI: 10.1128/mcb.3.4.539-550.1983 |
0.641 |
|
| 1981 |
Heintz N, Zernik M, Roeder RG. The structure of the human histone genes: clustered but not tandemly repeated. Cell. 24: 661-8. PMID 6265100 DOI: 10.1016/0092-8674(81)90092-1 |
0.46 |
|
| 1981 |
Roeder RG, Heintz N, Honda B, Lee D, Luse D, Matsui T, Segall J, Shastry B. Initiation of Eukaryotic Gene Transcription in Vitro Biochemical Society Transactions. 9: 120P-120P. DOI: 10.1042/bst009120p |
0.4 |
|
| 1980 |
Zernik M, Heintz N, Boime I, Roeder RG. Xenopus laevis histone genes: variant H1 genes are present in different clusters. Cell. 22: 807-15. PMID 7460012 DOI: 10.1016/0092-8674(80)90557-7 |
0.374 |
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