Ann Marshak-Rothstein - Publications

Affiliations: 
Boston University, Boston, MA, United States 
 Rheumatology University of Massachusetts Medical School, Worcester, MA, United States 
Area:
Microbiology Biology
Website:
https://profiles.umassmed.edu/display/130118

162 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Çakan E, Ah Kioon MD, Garcia-Carmona Y, Glauzy S, Oliver D, Yamakawa N, Vega Loza A, Du Y, Schickel JN, Boeckers JM, Yang C, Baldo A, Ivashkiv LB, Young RM, Staudt LM, ... ... Marshak-Rothstein A, et al. TLR9 ligand sequestration by chemokine CXCL4 negatively affects central B cell tolerance. The Journal of Experimental Medicine. 220. PMID 37773045 DOI: 10.1084/jem.20230944  0.458
2023 Raso F, Liu S, Simpson MJ, Barton GM, Mayer CT, Acharya M, Muppidi JR, Marshak-Rothstein A, Reboldi A. Antigen receptor signaling and cell death resistance controls intestinal humoral response zonation. Immunity. PMID 37714151 DOI: 10.1016/j.immuni.2023.08.018  0.394
2023 Gavin AL, Blane TR, Thinnes TC, Gerlt E, Marshak-Rothstein A, Huang D, Nemazee D. Disease in the Pld4thss/thss Model of Murine Lupus Requires TLR9. Immunohorizons. 7: 577-586. PMID 37555846 DOI: 10.4049/immunohorizons.2300058  0.321
2022 Kugler-Umana O, Zhang W, Kuang Y, Liang J, Castonguay CH, Tonkonogy SL, Marshak-Rothstein A, Devarajan P, Swain SL. IgD age-associated B cells are the progenitors of the main T-independent B cell response to infection that generates protective Ab and can be induced by an inactivated vaccine in the aged. Aging Cell. e13705. PMID 36056604 DOI: 10.1111/acel.13705  0.303
2022 Gao KM, Motwani M, Tedder T, Marshak-Rothstein A, Fitzgerald KA. Radioresistant cells initiate lymphocyte-dependent lung inflammation and IFNγ-dependent mortality in STING gain-of-function mice. Proceedings of the National Academy of Sciences of the United States of America. 119: e2202327119. PMID 35696583 DOI: 10.1073/pnas.2202327119  0.359
2021 Gao KM, Derr AG, Guo Z, Nundel K, Marshak-Rothstein A, Finberg RW, Wang JP. Human nasal wash RNA-seq reveals distinct cell-specific innate immune responses between influenza and SARS-CoV-2. Jci Insight. PMID 34618691 DOI: 10.1172/jci.insight.152288  0.316
2021 Motwani M, McGowan J, Antonovitch J, Gao KM, Jiang Z, Sharma S, Baltus GA, Nickerson KM, Marshak-Rothstein A, Fitzgerald KA. cGAS-STING Pathway Does Not Promote Autoimmunity in Murine Models of SLE. Frontiers in Immunology. 12: 605930. PMID 33854495 DOI: 10.3389/fimmu.2021.605930  0.303
2021 Gregory-Ksander M, Marshak-Rothstein A. The FasLane to ocular pathology-metalloproteinase cleavage of membrane-bound FasL determines FasL function. Journal of Leukocyte Biology. PMID 33565149 DOI: 10.1002/JLB.3RI1220-834R  0.317
2020 Marshak-Rothstein A, Manning CA, Baum R, Pawaria S, Gravallese EM. Interplay of Cyclic GMP-AMP Synthase/Stimulator of IFN Genes and Toll-Like Receptor Nucleic Acid Sensing Pathways in Autoinflammation and Abnormal Bone Formation due to DNaseII-Deficiency. Viral Immunology. 33: 246-249. PMID 32286184 DOI: 10.1089/Vim.2019.0191  0.343
2020 Garelli C, Mande P, Moses S, Pike K, Wong L, Marshak-Rothstein A, Richmond J. 091 B cells are required for development of skin lesions in a mouse model of cutaneous lupus erythematosus Journal of Investigative Dermatology. 140. DOI: 10.1016/J.Jid.2020.03.093  0.335
2019 Krishnan A, Kocab AJ, Zacks DN, Marshak-Rothstein A, Gregory-Ksander M. A small peptide antagonist of the Fas receptor inhibits neuroinflammation and prevents axon degeneration and retinal ganglion cell death in an inducible mouse model of glaucoma. Journal of Neuroinflammation. 16: 184. PMID 31570110 DOI: 10.1186/S12974-019-1576-3  0.337
2019 Nündel K, Marshak-Rothstein A. The role of nucleic acid sensors and type I IFNs in patient populations and animal models of autoinflammation. Current Opinion in Immunology. 61: 74-79. PMID 31569013 DOI: 10.1016/J.Coi.2019.08.003  0.345
2019 Nündel K, Mande P, Moses SL, Busto P, Cullen JL, Schmidt MR, Shlomchik MJ, Woodland RT, Marshak-Rothstein A. Cross-Reactive Antigen Expressed by B6 Splenocytes Drives Receptor Editing and Marginal Zone Differentiation of IgG2a-Reactive AM14 Vκ8 B Cells. Journal of Immunology (Baltimore, Md. : 1950). PMID 31534009 DOI: 10.4049/Jimmunol.1900499  0.53
2019 Pawaria S, Nündel K, Gao KM, Moses S, Busto P, Holt K, Sharma RB, Brehm MA, Gravallese EM, Socolovsky M, Christ A, Marshak-Rothstein A. The Role of IFNγ-Producing Th1 Cells in a Type I IFN-Independent Murine Model of Autoinflammation Resulting from DNase II-Deficiency. Arthritis & Rheumatology (Hoboken, N.J.). PMID 31464028 DOI: 10.1002/Art.41090  0.342
2019 Johnson JL, Scholz JL, Marshak-Rothstein A, Cancro MP. Molecular pattern recognition in peripheral B cell tolerance: lessons from age-associated B cells. Current Opinion in Immunology. 61: 33-38. PMID 31446338 DOI: 10.1016/J.Coi.2019.07.008  0.681
2019 Motwani M, Pawaria S, Bernier J, Moses S, Henry K, Fang T, Burkly L, Marshak-Rothstein A, Fitzgerald KA. Hierarchy of clinical manifestations in SAVI N153S and V154M mouse models. Proceedings of the National Academy of Sciences of the United States of America. PMID 30944222 DOI: 10.1073/Pnas.1818281116  0.393
2018 Gregory-Ksander M, Perez VL, Marshak-Rothstein A, Ksander BR. Soluble Fas ligand blocks destructive corneal inflammation in mouse models of corneal epithelial debridement and LPS induced keratitis. Experimental Eye Research. PMID 30365944 DOI: 10.1016/J.Exer.2018.10.013  0.362
2018 Mande P, Zirak B, Ko WC, Taravati K, Bride KL, Brodeur TY, Deng A, Dresser K, Jiang Z, Ettinger R, Fitzgerald KA, Rosenblum MD, Harris JE, Marshak-Rothstein A. Fas ligand promotes an inducible TLR-dependent model of cutaneous lupus-like inflammation. The Journal of Clinical Investigation. PMID 29889098 DOI: 10.1172/Jci98219  0.517
2018 Pelka K, Bertheloot D, Reimer E, Phulphagar K, Schmidt SV, Christ A, Stahl R, Watson N, Miyake K, Hacohen N, Haas A, Brinkmann MM, Marshak-Rothstein A, Meissner F, Latz E. The Chaperone UNC93B1 Regulates Toll-like Receptor Stability Independently of Endosomal TLR Transport. Immunity. 48: 911-922.e7. PMID 29768176 DOI: 10.1016/J.Immuni.2018.04.011  0.443
2018 O'Donnell JA, Lehman J, Roderick JE, Martinez-Marin D, Zelic M, Doran C, Hermance N, Lyle S, Pasparakis M, Fitzgerald KA, Marshak-Rothstein A, Kelliher MA. Correction: Dendritic Cell RIPK1 Maintains Immune Homeostasis by Preventing Inflammation and Autoimmunity. Journal of Immunology (Baltimore, Md. : 1950). PMID 29531167 DOI: 10.4049/Jimmunol.1800240  0.345
2018 Nundel K, Christ A, Mande P, Ko W, Harris JE, Latz E, Marshak-Rothstein A. II-01 TLR9-deficiency exacerbates autoimmune disease in models of SLE and cutaneous lupus through B cell independent mechanisms Lupus Science & Medicine. 5. DOI: 10.1136/Lupus-2018-Lsm.100  0.509
2017 O'Donnell JA, Lehman J, Roderick JE, Martinez-Marin D, Zelic M, Doran C, Hermance N, Lyle S, Pasparakis M, Fitzgerald KA, Marshak-Rothstein A, Kelliher MA. Dendritic Cell RIPK1 Maintains Immune Homeostasis by Preventing Inflammation and Autoimmunity. Journal of Immunology (Baltimore, Md. : 1950). PMID 29212904 DOI: 10.4049/Jimmunol.1701229  0.458
2017 Sindhava VJ, Oropallo MA, Moody K, Naradikian M, Higdon LE, Zhou L, Myles A, Green N, Nündel K, Stohl W, Schmidt AM, Cao W, Dorta-Estremera S, Kambayashi T, Marshak-Rothstein A, et al. A TLR9-dependent checkpoint governs B cell responses to DNA-containing antigens. The Journal of Clinical Investigation. PMID 28346226 DOI: 10.1172/Jci89931  0.795
2017 Giles JR, Neves AT, Marshak-Rothstein A, Shlomchik MJ. Autoreactive helper T cells alleviate the need for intrinsic TLR signaling in autoreactive B cell activation. Jci Insight. 2: e90870. PMID 28239656 DOI: 10.1172/Jci.Insight.90870  0.527
2016 Krishnan A, Fei F, Jones A, Busto P, Marshak-Rothstein A, Ksander BR, Gregory-Ksander M. Overexpression of Soluble Fas Ligand following Adeno-Associated Virus Gene Therapy Prevents Retinal Ganglion Cell Death in Chronic and Acute Murine Models of Glaucoma. Journal of Immunology (Baltimore, Md. : 1950). PMID 27849168 DOI: 10.4049/Jimmunol.1601488  0.37
2016 Baum R, Sharma S, Organ JM, Jakobs C, Hornung V, Burr DB, Marshak-Rothstein A, Fitzgerald KA, Gravallese EM. STING regulates abnormal bone formation induced by deficiency of DNase II. Arthritis & Rheumatology (Hoboken, N.J.). PMID 27740718 DOI: 10.1002/Art.39863  0.337
2016 Pawaria S, Sharma S, Baum R, Nündel K, Busto P, Gravallese EM, Fitzgerald KA, Marshak-Rothstein A. Taking the STING out of TLR-driven autoimmune diseases: good, bad, or indifferent? Journal of Leukocyte Biology. PMID 27531928 DOI: 10.1189/Jlb.3Mr0316-115R  0.446
2016 Bossaller L, Christ A, Pelka K, Nündel K, Chiang PI, Pang C, Mishra N, Busto P, Bonegio RG, Schmidt RE, Latz E, Marshak-Rothstein A. TLR9 Deficiency Leads to Accelerated Renal Disease and Myeloid Lineage Abnormalities in Pristane-Induced Murine Lupus. Journal of Immunology (Baltimore, Md. : 1950). PMID 27354219 DOI: 10.4049/Jimmunol.1501943  0.421
2016 Moody KL, Uccellini MB, Avalos AM, Marshak-Rothstein A, Viglianti GA. Toll-Like Receptor-Dependent Immune Complex Activation of B Cells and Dendritic Cells. Methods in Molecular Biology (Clifton, N.J.). 1390: 249-72. PMID 26803634 DOI: 10.1007/978-1-4939-3335-8_16  0.833
2016 Baum R, Nündel K, Pawaria S, Sharma S, Busto P, Fitzgerald KA, Gravallese EM, Marshak-Rothstein A. Synergy between Hematopoietic and Radioresistant Stromal Cells Is Required for Autoimmune Manifestations of DNase II-/-IFNaR-/- Mice. Journal of Immunology (Baltimore, Md. : 1950). 196: 1348-54. PMID 26729810 DOI: 10.4049/Jimmunol.1502130  0.454
2016 Marshak-Rothstein A. Autoimmunity - promoting and stabilizing innate immunity 'UNWUCHT'. Immunological Reviews. 269: 7-10. PMID 26683141 DOI: 10.1111/Imr.12387  0.366
2016 Nundel K, Christ A, Sharma S, Marshak-Rothstein A. II-14 disturbed clearance of apoptotic debris in pristane-treated tlr9ko mice leads to accumulation of a unique macrophage population Lupus Science & Medicine. 3. DOI: 10.1136/Lupus-2016-000179.44  0.49
2016 Sharma S, Campbell AM, Chan J, Schattgen SA, Orlowski GM, Nayar R, Huyler AH, Nündel K, Mohan C, Berg LJ, Shlomchik MJ, Marshak-Rothstein A, Fitzgerald KA. II-13 Suppression of systemic autoimmunity by the innate immune adaptor sting Lupus Science & Medicine. 3. DOI: 10.1136/Lupus-2016-000179.43  0.439
2016 Mande P, Brodeur T, Lee K, Marshak-Rothstein A. AI-14 Autoantibody production in an inducible model of cutaneous lupus Lupus Science & Medicine. 3. DOI: 10.1136/Lupus-2016-000179.14  0.5
2015 Matsumoto H, Murakami Y, Kataoka K, Notomi S, Mantopoulos D, Trichonas G, Miller JW, Gregory MS, Ksander BR, Marshak-Rothstein A, Vavvas DG. Membrane-bound and soluble Fas ligands have opposite functions in photoreceptor cell death following separation from the retinal pigment epithelium. Cell Death & Disease. 6: e1986. PMID 26583327 DOI: 10.1038/Cddis.2015.334  0.371
2015 Brodeur TY, Robidoux TE, Weinstein JS, Craft J, Swain SL, Marshak-Rothstein A. IL-21 Promotes Pulmonary Fibrosis through the Induction of Profibrotic CD8+ T Cells. Journal of Immunology (Baltimore, Md. : 1950). PMID 26519529 DOI: 10.4049/Jimmunol.1500777  0.316
2015 Pawaria S, Moody KL, Busto P, Nündel K, Baum R, Sharma S, Gravallese EM, Fitzgerald KA, Marshak-Rothstein A. An unexpected role for RNA-sensing toll-like receptors in a murine model of DNA accrual. Clinical and Experimental Rheumatology. 33: 70-3. PMID 26457825  0.321
2015 Sharma S, Fitzgerald KA, Cancro MP, Marshak-Rothstein A. Nucleic Acid-Sensing Receptors: Rheostats of Autoimmunity and Autoinflammation. Journal of Immunology (Baltimore, Md. : 1950). 195: 3507-12. PMID 26432899 DOI: 10.4049/Jimmunol.1500964  0.644
2015 Nündel K, Green NM, Shaffer AL, Moody KL, Busto P, Eilat D, Miyake K, Oropallo MA, Cancro MP, Marshak-Rothstein A. Cell-intrinsic expression of TLR9 in autoreactive B cells constrains BCR/TLR7-dependent responses. Journal of Immunology (Baltimore, Md. : 1950). 194: 2504-12. PMID 25681333 DOI: 10.4049/Jimmunol.1402425  0.786
2015 Sharma S, Campbell AM, Chan J, Schattgen SA, Orlowski GM, Nayar R, Huyler AH, Nündel K, Mohan C, Berg LJ, Shlomchik MJ, Marshak-Rothstein A, Fitzgerald KA. Suppression of systemic autoimmunity by the innate immune adaptor STING. Proceedings of the National Academy of Sciences of the United States of America. 112: E710-7. PMID 25646421 DOI: 10.1073/Pnas.1420217112  0.476
2015 Pawaria S, Moody K, Busto P, Nündel K, Choi CH, Ghayur T, Marshak-Rothstein A. Cutting Edge: DNase II deficiency prevents activation of autoreactive B cells by double-stranded DNA endogenous ligands. Journal of Immunology (Baltimore, Md. : 1950). 194: 1403-7. PMID 25601924 DOI: 10.4049/Jimmunol.1402893  0.524
2015 Baum R, Sharma S, Carpenter S, Li QZ, Busto P, Fitzgerald KA, Marshak-Rothstein A, Gravallese EM. Cutting edge: AIM2 and endosomal TLRs differentially regulate arthritis and autoantibody production in DNase II-deficient mice. Journal of Immunology (Baltimore, Md. : 1950). 194: 873-7. PMID 25548216 DOI: 10.4049/Jimmunol.1402573  0.405
2014 Pelka K, Phulphagar K, Zimmermann J, Stahl R, Schmid-Burgk JL, Schmidt T, Spille JH, Labzin LI, Agrawal S, Kandimalla ER, Casanova JL, Hornung V, Marshak-Rothstein A, Höning S, Latz E. Cutting edge: the UNC93B1 tyrosine-based motif regulates trafficking and TLR responses via separate mechanisms. Journal of Immunology (Baltimore, Md. : 1950). 193: 3257-61. PMID 25187660 DOI: 10.4049/Jimmunol.1301886  0.451
2014 Franklin BS, Bossaller L, De Nardo D, Ratter JM, Stutz A, Engels G, Brenker C, Nordhoff M, Mirandola SR, Al-Amoudi A, Mangan MS, Zimmer S, Monks BG, Fricke M, Schmidt RE, ... ... Marshak-Rothstein A, et al. The adaptor ASC has extracellular and 'prionoid' activities that propagate inflammation. Nature Immunology. 15: 727-37. PMID 24952505 DOI: 10.1038/Ni.2913  0.35
2014 Gratz IK, Rosenblum MD, Maurano MM, Paw JS, Truong HA, Marshak-Rothstein A, Abbas AK. Cutting edge: Self-antigen controls the balance between effector and regulatory T cells in peripheral tissues. Journal of Immunology (Baltimore, Md. : 1950). 192: 1351-5. PMID 24442443 DOI: 10.4049/Jimmunol.1301777  0.362
2013 Bossaller L, Rathinam VA, Bonegio R, Chiang PI, Busto P, Wespiser AR, Caffrey DR, Li QZ, Mohan C, Fitzgerald KA, Latz E, Marshak-Rothstein A. Overexpression of membrane-bound fas ligand (CD95L) exacerbates autoimmune disease and renal pathology in pristane-induced lupus. Journal of Immunology (Baltimore, Md. : 1950). 191: 2104-14. PMID 23918976 DOI: 10.4049/Jimmunol.1300341  0.4
2013 Nündel K, Busto P, Debatis M, Marshak-Rothstein A. The role of Bruton's tyrosine kinase in the development and BCR/TLR-dependent activation of AM14 rheumatoid factor B cells. Journal of Leukocyte Biology. 94: 865-75. PMID 23804807 DOI: 10.1189/Jlb.0313126  0.548
2013 Yasuda K, Nündel K, Watkins AA, Dhawan T, Bonegio RG, Ubellacker JM, Marshak-Rothstein A, Rifkin IR. Phenotype and function of B cells and dendritic cells from interferon regulatory factor 5-deficient mice with and without a mutation in DOCK2. International Immunology. 25: 295-306. PMID 23291967 DOI: 10.1093/Intimm/Dxs114  0.433
2013 Marshak-Rothstein A. From B-Cell Tolerance to Autoimmunity Blood. 122: SCI-1-SCI-1. DOI: 10.1182/Blood.V122.21.Sci-1.Sci-1  0.593
2013 Marshak-Rothstein A, Cancro MP. Toll-Like Receptor 9 and Toll-Like Receptor 7 in the Development and Regulation of Systemic Autoimmune Disease Biological Dna Sensor: the Impact of Nucleic Acids On Diseases and Vaccinology. 133-152. DOI: 10.1016/B978-0-12-404732-7.00006-X  0.708
2012 Bossaller L, Chiang PI, Schmidt-Lauber C, Ganesan S, Kaiser WJ, Rathinam VA, Mocarski ES, Subramanian D, Green DR, Silverman N, Fitzgerald KA, Marshak-Rothstein A, Latz E. Cutting edge: FAS (CD95) mediates noncanonical IL-1β and IL-18 maturation via caspase-8 in an RIP3-independent manner. Journal of Immunology (Baltimore, Md. : 1950). 189: 5508-12. PMID 23144495 DOI: 10.4049/Jimmunol.1202121  0.595
2012 Green NM, Moody KS, Debatis M, Marshak-Rothstein A. Activation of autoreactive B cells by endogenous TLR7 and TLR3 RNA ligands. The Journal of Biological Chemistry. 287: 39789-99. PMID 23019335 DOI: 10.1074/Jbc.M112.383000  0.672
2012 Vas J, Grönwall C, Marshak-Rothstein A, Silverman GJ. Natural antibody to apoptotic cell membranes inhibits the proinflammatory properties of lupus autoantibody immune complexes. Arthritis and Rheumatism. 64: 3388-98. PMID 22577035 DOI: 10.1002/Art.34537  0.469
2012 Kiefer K, Oropallo MA, Cancro MP, Marshak-Rothstein A. Role of type I interferons in the activation of autoreactive B cells. Immunology and Cell Biology. 90: 498-504. PMID 22430248 DOI: 10.1038/Icb.2012.10  0.685
2012 Han H, Xu W, Headley MB, Jessup HK, Lee KS, Omori M, Comeau MR, Marshak-Rothstein A, Ziegler SF. Thymic stromal lymphopoietin (TSLP)-mediated dermal inflammation aggravates experimental asthma Mucosal Immunology. 5: 342-351. PMID 22354320 DOI: 10.1038/Mi.2012.14  0.326
2012 Uccellini MB, Busto P, Debatis M, Marshak-Rothstein A, Viglianti GA. Selective binding of anti-DNA antibodies to native dsDNA fragments of differing sequence. Immunology Letters. 143: 85-91. PMID 22285306 DOI: 10.1016/J.Imlet.2012.01.003  0.767
2011 Oropallo MA, Kiefer K, Marshak-Rothstein A, Cancro MP. Beyond transitional selection: New roles for BLyS in peripheral tolerance. Drug Development Research. 72: 779-787. PMID 22323842 DOI: 10.1002/Ddr.20487  0.69
2011 Rosenblum MD, Gratz IK, Paw JS, Lee K, Marshak-Rothstein A, Abbas AK. Response to self antigen imprints regulatory memory in tissues. Nature. 480: 538-42. PMID 22121024 DOI: 10.1038/Nature10664  0.394
2011 Harris JE, Marshak-Rothstein A. Editorial: Interfering with B cell immunity. Journal of Leukocyte Biology. 89: 805-6. PMID 21628334 DOI: 10.1189/Jlb.0111042  0.499
2011 Gregory MS, Hackett CG, Abernathy EF, Lee KS, Saff RR, Hohlbaum AM, Moody KS, Hobson MW, Jones A, Kolovou P, Karray S, Giani A, John SW, Chen DF, Marshak-Rothstein A, et al. Opposing roles for membrane bound and soluble Fas ligand in glaucoma-associated retinal ganglion cell death. Plos One. 6: e17659. PMID 21479271 DOI: 10.1371/Journal.Pone.0017659  0.734
2011 Green NM, Marshak-Rothstein A. Toll-like receptor driven B cell activation in the induction of systemic autoimmunity. Seminars in Immunology. 23: 106-12. PMID 21306913 DOI: 10.1016/J.Smim.2011.01.016  0.726
2010 Avalos AM, Uccellini MB, Lenert P, Viglianti GA, Marshak-Rothstein A. FcγRIIB regulation of BCR/TLR-dependent autoreactive B-cell responses. European Journal of Immunology. 40: 2692-8. PMID 20809520 DOI: 10.1002/Eji.200940184  0.835
2010 Misra RS, Shi G, Moreno-Garcia ME, Thankappan A, Tighe M, Mousseau B, Kusser K, Becker-Herman S, Hudkins KL, Dunn R, Kehry MR, Migone TS, Marshak-Rothstein A, Simon M, Randall TD, et al. G alpha q-containing G proteins regulate B cell selection and survival and are required to prevent B cell-dependent autoimmunity. The Journal of Experimental Medicine. 207: 1775-89. PMID 20624888 DOI: 10.1084/Jem.20092735  0.47
2010 Farina GA, York MR, Di Marzio M, Collins CA, Meller S, Homey B, Rifkin IR, Marshak-Rothstein A, Radstake TR, Lafyatis R. Poly(I:C) drives type I IFN- and TGFβ-mediated inflammation and dermal fibrosis simulating altered gene expression in systemic sclerosis. The Journal of Investigative Dermatology. 130: 2583-93. PMID 20613770 DOI: 10.1038/Jid.2010.200  0.43
2010 Avalos AM, Kiefer K, Tian J, Christensen S, Shlomchik M, Coyle AJ, Marshak-Rothstein A. RAGE-independent autoreactive B cell activation in response to chromatin and HMGB1/DNA immune complexes. Autoimmunity. 43: 103-10. PMID 20014975 DOI: 10.3109/08916930903384591  0.804
2010 Avalos AM, Busconi L, Marshak-Rothstein A. Regulation of autoreactive B cell responses to endogenous TLR ligands. Autoimmunity. 43: 76-83. PMID 20014959 DOI: 10.3109/08916930903374618  0.8
2010 Richez C, Yasuda K, Bonegio RG, Watkins AA, Aprahamian T, Busto P, Richards RJ, Liu CL, Cheung R, Utz PJ, Marshak-Rothstein A, Rifkin IR. IFN regulatory factor 5 is required for disease development in the FcgammaRIIB-/-Yaa and FcgammaRIIB-/- mouse models of systemic lupus erythematosus. Journal of Immunology (Baltimore, Md. : 1950). 184: 796-806. PMID 20007534 DOI: 10.4049/Jimmunol.0901748  0.376
2009 Avalos AM, Latz E, Mousseau B, Christensen SR, Shlomchik MJ, Lund F, Marshak-Rothstein A. Differential cytokine production and bystander activation of autoreactive B cells in response to CpG-A and CpG-B oligonucleotides. Journal of Immunology (Baltimore, Md. : 1950). 183: 6262-8. PMID 19864612 DOI: 10.4049/Jimmunol.0901941  0.779
2009 Yasuda K, Richez C, Uccellini MB, Richards RJ, Bonegio RG, Akira S, Monestier M, Corley RB, Viglianti GA, Marshak-Rothstein A, Rifkin IR. Requirement for DNA CpG content in TLR9-dependent dendritic cell activation induced by DNA-containing immune complexes. Journal of Immunology (Baltimore, Md. : 1950). 183: 3109-17. PMID 19648272 DOI: 10.4049/Jimmunol.0900399  0.77
2009 Green NM, Laws A, Kiefer K, Busconi L, Kim YM, Brinkmann MM, Trail EH, Yasuda K, Christensen SR, Shlomchik MJ, Vogel S, Connor JH, Ploegh H, Eilat D, Rifkin IR, ... ... Marshak-Rothstein A, et al. Murine B cell response to TLR7 ligands depends on an IFN-beta feedback loop. Journal of Immunology (Baltimore, Md. : 1950). 183: 1569-76. PMID 19587008 DOI: 10.4049/Jimmunol.0803899  0.707
2009 Lenert P, Yasuda K, Busconi L, Nelson P, Fleenor C, Ratnabalasuriar RS, Nagy PL, Ashman RF, Rifkin IR, Marshak-Rothstein A. DNA-like class R inhibitory oligonucleotides (INH-ODNs) preferentially block autoantigen-induced B-cell and dendritic cell activation in vitro and autoantibody production in lupus-prone MRL-Fas(lpr/lpr) mice in vivo. Arthritis Research & Therapy. 11: R79. PMID 19476613 DOI: 10.1186/Ar2710  0.576
2009 Uccellini MB, Avalos AM, Marshak-Rothstein A, Viglianti GA. Toll-like receptor-dependent immune complex activation of B cells and dendritic cells. Methods in Molecular Biology (Clifton, N.J.). 517: 363-80. PMID 19378022 DOI: 10.1007/978-1-59745-541-1_22  0.84
2008 Uccellini MB, Busconi L, Green NM, Busto P, Christensen SR, Shlomchik MJ, Marshak-Rothstein A, Viglianti GA. Autoreactive B cells discriminate CpG-rich and CpG-poor DNA and this response is modulated by IFN-alpha. Journal of Immunology (Baltimore, Md. : 1950). 181: 5875-84. PMID 18941176 DOI: 10.4049/Jimmunol.181.9.5875  0.827
2007 Gregory MS, Saff RR, Marshak-Rothstein A, Ksander BR. Control of ocular tumor growth and metastatic spread by soluble and membrane Fas ligand. Cancer Research. 67: 11951-8. PMID 18089826 DOI: 10.1158/0008-5472.Can-07-0780  0.717
2007 Lafyatis R, Marshak-Rothstein A. Toll-like receptors and innate immune responses in systemic lupus erythematosus. Arthritis Research & Therapy. 9: 222. PMID 18086320 DOI: 10.1186/Ar2321  0.434
2007 Marshak-Rothstein A, Ohashi PS. Intricate connections between innate and adaptive autoimmunity. Current Opinion in Immunology. 19: 603-5. PMID 18083508 DOI: 10.1016/J.Coi.2007.10.001  0.304
2007 Busconi L, Bauer JW, Tumang JR, Laws A, Perkins-Mesires K, Tabor AS, Lau C, Corley RB, Rothstein TL, Lund FE, Behrens TW, Marshak-Rothstein A. Functional outcome of B cell activation by chromatin immune complex engagement of the B cell receptor and TLR9. Journal of Immunology (Baltimore, Md. : 1950). 179: 7397-405. PMID 18025183 DOI: 10.4049/Jimmunol.179.11.7397  0.57
2007 Yasuda K, Richez C, Maciaszek JW, Agrawal N, Akira S, Marshak-Rothstein A, Rifkin IR. Murine dendritic cell type I IFN production induced by human IgG-RNA immune complexes is IFN regulatory factor (IRF)5 and IRF7 dependent and is required for IL-6 production. Journal of Immunology (Baltimore, Md. : 1950). 178: 6876-85. PMID 17513736 DOI: 10.4049/Jimmunol.178.11.6876  0.416
2007 Tian J, Avalos AM, Mao SY, Chen B, Senthil K, Wu H, Parroche P, Drabic S, Golenbock D, Sirois C, Hua J, An LL, Audoly L, La Rosa G, Bierhaus A, ... ... Marshak-Rothstein A, et al. Toll-like receptor 9-dependent activation by DNA-containing immune complexes is mediated by HMGB1 and RAGE. Nature Immunology. 8: 487-96. PMID 17417641 DOI: 10.1038/Ni1457  0.792
2007 Marshak-Rothstein A, Rifkin IR. Immunologically active autoantigens: the role of toll-like receptors in the development of chronic inflammatory disease. Annual Review of Immunology. 25: 419-41. PMID 17378763 DOI: 10.1146/Annurev.Immunol.22.012703.104514  0.489
2007 Tian J, Avalos AM, Mao S, Chen B, Senthil K, Wu H, Parroche P, Drabic S, Golenbock D, Sirois C, Hua J, An LL, Audoly L, La Rosa G, Bierhaus A, ... ... Marshak-Rothstein A, et al. Erratum: Corrigendum: Toll-like receptor 9—dependent activation by DNA-containing immune complexes is mediated by HMGB1 and RAGE Nature Immunology. 8: 780-780. DOI: 10.1038/Ni0707-780B  0.752
2007 Busconi L, Nelson P, Marshak-Rothstein A. 14 Regulation of Cytokine Production in Autoreactive AM14 B Cells Stimulated by Chromatin Immunecomplexes Cytokine. 39: 4-5. DOI: 10.1016/J.Cyto.2007.07.019  0.411
2006 Busconi L, Lau CM, Tabor AS, Uccellini MB, Ruhe Z, Akira S, Viglianti GA, Rifkin IR, Marshak-Rothstein A. DNA and RNA autoantigens as autoadjuvants. Journal of Endotoxin Research. 12: 379-84. PMID 17254393 DOI: 10.1177/09680519060120060901  0.815
2006 Marshak-Rothstein A. Toll-like receptors in systemic autoimmune disease. Nature Reviews. Immunology. 6: 823-35. PMID 17063184 DOI: 10.1038/Nri1957  0.513
2006 Lafyatis R, York M, Marshak-Rothstein A. Antimalarial agents: closing the gate on Toll-like receptors? Arthritis and Rheumatism. 54: 3068-70. PMID 17009223 DOI: 10.1002/Art.22157  0.476
2006 Marshak-Rothstein A. Tolling for autoimmunity-prime time for 7. Immunity. 25: 397-9. PMID 16979573 DOI: 10.1016/J.Immuni.2006.08.011  0.309
2006 Beaudette-Zlatanova BC, Ling T, Shlomchik MJ, Marshak-Rothstein A, Rifkin IR. B cells and dendritic cells from V kappa 8 light chain transgenic mice activate MRL-lpr/gld CD4+ T cells. Journal of Immunology (Baltimore, Md. : 1950). 177: 45-52. PMID 16785497 DOI: 10.4049/Jimmunol.177.1.45  0.465
2005 Lau CM, Broughton C, Tabor AS, Akira S, Flavell RA, Mamula MJ, Christensen SR, Shlomchik MJ, Viglianti GA, Rifkin IR, Marshak-Rothstein A. RNA-associated autoantigens activate B cells by combined B cell antigen receptor/Toll-like receptor 7 engagement. The Journal of Experimental Medicine. 202: 1171-7. PMID 16260486 DOI: 10.1084/Jem.20050630  0.535
2005 Gregory MS, Koh S, Huang E, Saff RR, Marshak-Rothstein A, Mukai S, Ksander BR. A novel treatment for ocular tumors using membrane FasL vesicles to activate innate immunity and terminate immune privilege. Investigative Ophthalmology & Visual Science. 46: 2495-502. PMID 15980241 DOI: 10.1167/Iovs.05-0048  0.741
2005 William J, Euler C, Leadbetter E, Marshak-Rothstein A, Shlomchik MJ. Visualizing the onset and evolution of an autoantibody response in systemic autoimmunity. Journal of Immunology (Baltimore, Md. : 1950). 174: 6872-8. PMID 15905529 DOI: 10.4049/Jimmunol.174.11.6872  0.763
2005 Rifkin IR, Leadbetter EA, Busconi L, Viglianti G, Marshak-Rothstein A. Toll-like receptors, endogenous ligands, and systemic autoimmune disease. Immunological Reviews. 204: 27-42. PMID 15790348 DOI: 10.1111/J.0105-2896.2005.00239.X  0.759
2005 Marshak-Rothstein A, Busconi L, Lau CM, Uccellini M, Viglianti GA, Rifkin IR. The role of toll-like receptors in systemic autoimmune disease International Congress Series. 1285: 42-49. DOI: 10.1016/j.ics.2005.07.101  0.819
2004 Marshak-Rothstein A, Busconi L, Lau CM, Tabor AS, Leadbetter EA, Akira S, Krieg AM, Lipford GB, Viglianti GA, Rifkin IR. Comparison of CpG s-ODNs, chromatin immune complexes, and dsDNA fragment immune complexes in the TLR9-dependent activation of rheumatoid factor B cells. Journal of Endotoxin Research. 10: 247-51. PMID 15373969 DOI: 10.1177/09680519040100040801  0.786
2004 Funatake CJ, Dearstyne EA, Steppan LB, Shepherd DM, Spanjaard ES, Marshak-Rothstein A, Kerkvliet NI. Early consequences of 2,3,7,8-tetrachlorodibenzo-p-dioxin exposure on the activation and survival of antigen-specific T cells. Toxicological Sciences : An Official Journal of the Society of Toxicology. 82: 129-42. PMID 15310856 DOI: 10.1093/Toxsci/Kfh245  0.774
2004 Marshak-Rothstein A, Busconi L, Rifkin IR, Viglianti GA. The stimulation of Toll-like receptors by nuclear antigens: a link between apoptosis and autoimmunity. Rheumatic Diseases Clinics of North America. 30: 559-74, ix. PMID 15261341 DOI: 10.1016/J.Rdc.2004.04.005  0.446
2004 Boulé MW, Broughton C, Mackay F, Akira S, Marshak-Rothstein A, Rifkin IR. Toll-like receptor 9-dependent and -independent dendritic cell activation by chromatin-immunoglobulin G complexes. The Journal of Experimental Medicine. 199: 1631-40. PMID 15197227 DOI: 10.1084/Jem.20031942  0.494
2004 Saff RR, Spanjaard ES, Hohlbaum AM, Marshak-Rothstein A. Activation-induced cell death limits effector function of CD4 tumor-specific T cells. Journal of Immunology (Baltimore, Md. : 1950). 172: 6598-606. PMID 15153474 DOI: 10.4049/Jimmunol.172.11.6598  0.772
2004 Xiao S, Zhang X, Mann KK, Jodo S, Li L, Jarjour WN, Marshak-Rothstein A, Sherr DH, Ju ST. Changes in sensitivity of peripheral lymphocytes of autoimmune gld mice to FasL-mediated apoptosis reveal a mechanism for the preferential deletion of CD4-CD8-B220+ T cells. International Immunology. 16: 759-66. PMID 15096479 DOI: 10.1093/Intimm/Dxh078  0.424
2003 Viglianti GA, Lau CM, Hanley TM, Miko BA, Shlomchik MJ, Marshak-Rothstein A. Activation of autoreactive B cells by CpG dsDNA. Immunity. 19: 837-47. PMID 14670301 DOI: 10.1016/S1074-7613(03)00323-6  0.576
2003 Rifkin IR, Marshak-Rothstein A. T-bet: the Toll-bridge to class-switch recombination? Nature Immunology. 4: 650-2. PMID 12830144 DOI: 10.1038/Ni0703-650  0.432
2003 Leadbetter EA, Rifkin IR, Marshak-Rothstein A. Toll-like receptors and activation of autoreactive B cells. Current Directions in Autoimmunity. 6: 105-22. PMID 12408049 DOI: 10.1159/000066858  0.773
2002 Xiao S, Jodo S, Sung SS, Marshak-Rothstein A, Ju ST. A novel signaling mechanism for soluble CD95 ligand. Synergy with anti-CD95 monoclonal antibodies for apoptosis and NF-kappaB nuclear translocation. The Journal of Biological Chemistry. 277: 50907-13. PMID 12393889 DOI: 10.1074/Jbc.M206093200  0.336
2002 Gregory MS, Repp AC, Holhbaum AM, Saff RR, Marshak-Rothstein A, Ksander BR. Membrane Fas ligand activates innate immunity and terminates ocular immune privilege. Journal of Immunology (Baltimore, Md. : 1950). 169: 2727-35. PMID 12193747 DOI: 10.4049/Jimmunol.169.5.2727  0.748
2002 Hohlbaum AM, Saff RR, Marshak-Rothstein A. Fas-ligand--iron fist or Achilles' heel? Clinical Immunology (Orlando, Fla.). 103: 1-6. PMID 11987979 DOI: 10.1006/Clim.2001.5165  0.71
2002 Leadbetter EA, Rifkin IR, Hohlbaum AM, Beaudette BC, Shlomchik MJ, Marshak-Rothstein A. Chromatin-IgG complexes activate B cells by dual engagement of IgM and Toll-like receptors. Nature. 416: 603-7. PMID 11948342 DOI: 10.1038/416603A  0.798
2001 Xiao S, Marshak-Rothstein A, Ju ST. Sp1 is the major fasl gene activator in abnormal CD4-CD8-B220+ T cells of lpr and gld mice European Journal of Immunology. 31: 3339-3348. PMID 11745351 DOI: 10.1002/1521-4141(200111)31:11<3339::Aid-Immu3339>3.0.Co;2-U  0.378
2001 Hohlbaum AM, Gregory MS, Ju ST, Marshak-Rothstein A. Fas ligand engagement of resident peritoneal macrophages in vivo induces apoptosis and the production of neutrophil chemotactic factors Journal of Immunology. 167: 6217-6224. PMID 11714783 DOI: 10.4049/Jimmunol.167.11.6217  0.413
2001 Jodo S, Xiao S, Hohlbaum A, Strehlow D, Marshak-Rothstein A, Ju ST. Apoptosis-inducing membrane vesicles: A novel agent with unique properties Journal of Biological Chemistry. 276: 39938-39944. PMID 11546786 DOI: 10.1074/Jbc.M107005200  0.403
2000 Jodo S, Hohlbaum AM, Xiao S, Chan D, Strehlow D, Sherr DH, Marshak-Rothstein A, Ju ST. CD95 (Fas) ligand-expressing vesicles display antibody-mediated, FcR-dependent enhancement of cytotoxicity Journal of Immunology. 165: 5487-5494. PMID 11067901 DOI: 10.4049/Jimmunol.165.10.5487  0.352
2000 Rifkin IR, Leadbetter EA, Beaudette BC, Kiani C, Monestier M, Shlomchik MJ, Marshak-Rothstein A. Immune complexes present in the sera of autoimmune mice activate rheumatoid factor B cells. Journal of Immunology (Baltimore, Md. : 1950). 165: 1626-33. PMID 10903773 DOI: 10.4049/Jimmunol.165.3.1626  0.796
2000 Zhu B, Beaudette BC, Rifkin IR, Marshak-Rothstein A. Double mutant MRL-lpr/lpr-gld/gld cells fail to trigger lpr-graft-versus-host disease in syngeneic wild-type recipient mice, but can induce wild-type B cells to make autoantibody. European Journal of Immunology. 30: 1778-84. PMID 10898516 DOI: 10.1002/1521-4141(200006)30:6<1778::Aid-Immu1778>3.0.Co;2-D  0.621
2000 Gochuico BR, Zhang J, Ma BY, Marshak-Rothstein A, Fine A. TRAIL expression in vascular smooth muscle. American Journal of Physiology. Lung Cellular and Molecular Physiology. 278: L1045-50. PMID 10781437 DOI: 10.1152/Ajplung.2000.278.5.L1045  0.401
2000 Hohlbaum AM, Moe S, Marshak-Rothstein A. Opposing effects of transmembrane and soluble Fas ligand expression on inflammation and tumor cell survival Journal of Experimental Medicine. 191: 1209-1219. PMID 10748238 DOI: 10.1084/Jem.191.7.1209  0.424
2000 Wang JKM, Ju ST, Marshak-Rothstein A. Protection of T cells from activation-induced cell death by Fas+ B cells European Journal of Immunology. 30: 931-937. PMID 10741411 DOI: 10.1002/1521-4141(200003)30:3<931::Aid-Immu931>3.0.Co;2-H  0.519
2000 Boes M, Schmidt T, Linkemann K, Beaudette BC, Marshak-Rothstein A, Chen J. Accelerated development of IgG autoantibodies and autoimmune disease in the absence of secreted IgM Proceedings of the National Academy of Sciences of the United States of America. 97: 1184-1189. PMID 10655505 DOI: 10.1073/Pnas.97.3.1184  0.384
1999 Rifkin IR, Marshak-Rothstein A. Fas and Fas ligand in autoimmunity Current Directions in Autoimmunity. 1: 31-55. PMID 11791447 DOI: 10.1159/000060496  0.314
1999 Xiao S, Matsui K, Fine A, Zhu B, Marshak-Rothstein A, Widom RL, Ju ST. FasL promoter activation by IL-2 through SP1 and NFAT but not Egr-2 and Egr-3. European Journal of Immunology. 29: 3456-65. PMID 10556800 DOI: 10.1002/(Sici)1521-4141(199911)29:11<3456::Aid-Immu3456>3.0.Co;2-B  0.545
1999 Zhang J, Ma B, Marshak-Rothstein A, Fine A. Characterization of a novel cis-element that regulates Fas ligand expression in corneal endothelial cells. The Journal of Biological Chemistry. 274: 26537-42. PMID 10473616 DOI: 10.1074/Jbc.274.37.26537  0.416
1999 Morgan G, Smith S, Pak J, Marshak-Rothstein A, Fissore R, Osborne B. Characterization of a mutant T-cell hybridoma line with defects in the TCR-mediated apoptotic pathway Cell Death and Differentiation. 6: 36-47. PMID 10200546 DOI: 10.1038/Sj.Cdd.4400447  0.401
1998 Rifkin IR, Channavajhala PL, Kiefer HL, Carmack AJ, Landesman-Bollag E, Beaudette BC, Jersky B, Salant DJ, Ju ST, Marshak-Rothstein A, Seldin DC. Acceleration of lpr lymphoproliferative and autoimmune disease by transgenic protein kinase CK2 alpha. Journal of Immunology (Baltimore, Md. : 1950). 161: 5164-70. PMID 9820486  0.304
1998 Matsui K, Fine A, Zhu B, Marshak-Rothstein A, Ju ST. Identification of two NF-kappa B sites in mouse CD95 ligand (Fas ligand) promoter: functional analysis in T cell hybridoma. Journal of Immunology (Baltimore, Md. : 1950). 161: 3469-73. PMID 9759866  0.535
1998 Foote LC, Marshak-Rothstein A, Rothstein TL. Tolerant B lymphocytes acquire resistance to Fas-mediated apoptosis after treatment with interleukin 4 but not after treatment with specific antigen unless a surface immunoglobulin threshold is exceeded Journal of Experimental Medicine. 187: 847-853. PMID 9500787 DOI: 10.1084/Jem.187.6.847  0.472
1997 Wang JK, Zhu B, Ju ST, Tschopp J, Marshak-Rothstein A. CD4+ T cells reactivated with superantigen are both more sensitive to FasL-mediated killing and express a higher level of FasL. Cellular Immunology. 179: 153-64. PMID 9268499 DOI: 10.1006/Cimm.1997.1159  0.621
1997 Jacobson BA, Foote LC, Panka DJ, Ju ST, Rothstein TL, Marshak-Rothstein A. Unique site of autoantibody production in Fas-deficient mice Annals of the New York Academy of Sciences. 815: 218-229. PMID 9186658 DOI: 10.1111/J.1749-6632.1997.Tb52063.X  0.414
1997 Jacobson BA, Rothstein TL, Marshak-Rothstein A. Unique site of IgG2a and rheumatoid factor production in MRL/lpr mice Immunological Reviews. 156: 103-110. PMID 9176703 DOI: 10.1111/J.1600-065X.1997.Tb00962.X  0.417
1996 Elkon KB, Marshak-Rothstein A. B cells in systemic autoimmune disease: Recent insights from Fas-deficient mice and men Current Opinion in Immunology. 8: 852-859. PMID 8994866 DOI: 10.1016/S0952-7915(96)80015-X  0.519
1996 Jacobson BA, Rothstein TL, Marshak-Rothstein A. The role of Fas/FasL interactions in the regulation of B cell function Behring Institute Mitteilungen. 185-199. PMID 8950476  0.355
1996 Rothstein TL, Foote LC, Schneider TJ, Fischer GM, Jacobson BA, Lynch DH, Ju ST, Marshak-Rothstein A. Inducible resistance to Fas-mediated apoptosis in primary B lymphocytes Advances in Experimental Medicine and Biology. 406: 177-189. PMID 8910684 DOI: 10.1007/978-1-4899-0274-0_19  0.495
1996 Foote LC, Schneider TJ, Fischer GM, Wang JKM, Rasmussen B, Campbell KA, Lynch DH, Ju ST, Marshak-Rothstein A, Rothstein TL. Intracellular Signaling for Inducible Antigen Receptor-Mediated Fas Resistance in B Cells Journal of Immunology. 157: 1878-1885. PMID 8757305  0.3
1996 Christianson GJ, Blankenburg RL, Duffy TM, Panka D, Roths JB, Marshak-Rothstein A, Roopenian DC. β2-Microglobulin dependence of the lupus-like autoimmune syndrome of MRL-lpr mice Journal of Immunology. 156: 4932-4939. PMID 8648144  0.311
1996 Ozdemirli M, El-Khatib M, Foote LC, Wang JKM, Marshak-Rothstein A, Rothstein TL, Ju ST. Fas (CD95)/Fas ligand interactions regulate antigen-specific, major histocompatibility complex-restricted T/B cell proliferative responses European Journal of Immunology. 26: 415-419. PMID 8617312 DOI: 10.1002/Eji.1830260222  0.495
1996 Cui H, El-Khatib M, Sherr DH, Ettinger R, Sy MS, Marshak-Rothstein A, Ju ST. Characterization of lpr-derived T cell hybridomas: Fas-deficient hybridomas are deathless, growth-arrested, and cytotoxic upon activation Cellular Immunology. 167: 302-312. PMID 8603440 DOI: 10.1006/Cimm.1996.0039  0.441
1996 Cui H, Sherr DH, El-Khatib M, Matsui K, Panka DJ, Marshak-Rothstein A, Ju ST. Regulation of T-Cell death genes: Selective inhibition of FasL-but not Fas-mediated function Cellular Immunology. 167: 276-284. PMID 8603437 DOI: 10.1006/Cimm.1996.0036  0.376
1995 Jacobson BA, Panka DJ, Nguyen KA, Erikson J, Abbas AK, Marshak-Rothstein A. Anatomy of autoantibody production: dominant localization of antibody-producing cells to T cell zones in Fas-deficient mice. Immunity. 3: 509-19. PMID 7584141 DOI: 10.1016/1074-7613(95)90179-5  0.456
1995 Ettinger R, Panka DJ, Wang JKM, Stanger BZ, Ju ST, Marshak-Rothstein A. Fas ligand-mediated cytotoxicity is directly responsible for apoptosis of normal CD4+ T cells responding to a bacterial superantigen Journal of Immunology. 154: 4302-4308. PMID 7536768  0.343
1995 Rothstein TL, Wang JKM, Panka DJ, Foote LC, Wang Z, Stanger B, Cui H, Ju ST, Marshak-Rothstein A. Protection against Fas-dependent Thl-mediated apoptosis by antigen receptor engagement in B cells Nature. 374: 163-165. PMID 7533263 DOI: 10.1038/374163A0  0.499
1995 Ju ST, Panka DJ, Cui H, Ettinger R, Ei-Khatib M, Sherr DH, Stanger BZ, Marshak-Rothstein A. Fas(CD95)/FasL interactions required for programmed cell death after T-cell activation Nature. 373: 444-448. PMID 7530337 DOI: 10.1038/373444A0  0.432
1994 Ettinger R, Wang JKM, Bossu P, Papas K, Sidman CL, Abbas AK, Marshak-Rothstein A. Functional distinctions between MRL-lpr and MRL-gld lymphocytes: Normal cells reverse the gld but not lpr immunoregulatory defect Journal of Immunology. 152: 1557-1568. PMID 8120369  0.337
1994 Singer GG, Carrera AC, Marshak-Rothstein A, Martínez-A C, Abbas AK. Apoptosis, fas and systemic autoimmunity: the MRL-Ipr/Ipr model Current Opinion in Immunology. 6: 913-920. PMID 7536012 DOI: 10.1016/0952-7915(94)90013-2  0.382
1994 Ju ST, Cui H, Panka DJ, Ettinger R, Marshak-Rothstein A. Participation of target Fas protein in apoptosis pathway induced by CD4+ Th1 and CD8+ cytotoxic T cells Proceedings of the National Academy of Sciences of the United States of America. 91: 4185-4189. PMID 7514297 DOI: 10.1073/Pnas.91.10.4185  0.358
1993 Panka DJ, Very DL, Jacobson BA, Kussie PH, Parhami-Seren B, Margolies MN, Marshak-Rothstein A. Defining the structural correlates responsible for loss of arsonate affinity in an IdCR antibody isolated from an autoimmune mouse Molecular Immunology. 30: 1013-1020. PMID 8350871 DOI: 10.1016/0161-5890(93)90126-V  0.36
1993 Very DL, Panka DJ, Weissman D, Wysocki L, Manser T, Marshak-Rothstein A. Lack of connectivity between the induced and autoimmune repertoires of lpr/lpr mice Immunology. 80: 518-526. PMID 8307604  0.36
1992 Glaser RM, Mahon CA, Marshak-Rothstein A. Persistence of lpr/lpr-derived lgG2a secreting B cells in normal → lpr/lpr adult radiation chimeras or lpr/lpr → normal kidney capsule chimeras Cellular Immunology. 142: 313-325. PMID 1623555 DOI: 10.1016/0008-8749(92)90293-X  0.481
1992 Berney T, Fulpius T, Shibata T, Reininger L, Van Snick J, Shan H, Weigert M, Marshak-rothstein A, Lzui S. Selective pathogenicity of murine rheumatoid factors of the cryoprecipitable IgG3 subclass International Immunology. 4: 93-99. PMID 1540551 DOI: 10.1093/Intimm/4.1.93  0.324
1991 Nemazee D, Guiet C, Buerki K, Marshak-Rothstein A. B lymphocytes from the autoimmune-prone mouse strain MLR/lpr manifest an intrinsic defect in tetraparental MRL/lpr in equilibrium DBA/2 chimeras. Journal of Immunology (Baltimore, Md. : 1950). 147: 2536-9. PMID 1918976  0.32
1991 Bossú P, Ettinger R, Marshak-Rothstein A, Abbas AK. Analysis of lymphocyte responses in autoimmune MRL LPR/LPR mice Cytokine. 3: 506. DOI: 10.1016/1043-4666(91)90386-R  0.332
1990 Perkins DL, Glaser RM, Mahon CA, Michaelson J, Marshak-Rothstein A. Evidence for an intrinsic B cell defect in lpr/lpr mice apparent in neonatal chimeras Journal of Immunology. 145: 549-555. PMID 2365994  0.323
1990 Shlomchik M, Mascelli M, Shan H, Radic MZ, Pisetsky D, Marshak-Rothstein A, Weigert M. Anti-DNA antibodies from autoimmune mice arise by clonal expansion and somatic mutation Journal of Experimental Medicine. 171: 265-297. PMID 2104919 DOI: 10.1084/Jem.171.1.265  0.454
1989 Wolfowicz CB, Lyons S, Mahon CA, Marshak-Rothstein A, Rothstein TL. Isolation of self-recognizing IgG2a monoclonal rheumatoid factors Clinical Immunology and Immunopathology. 52: 313-322. PMID 2736811 DOI: 10.1016/0090-1229(89)90182-7  0.356
1988 Marshak-Rothstein A. Origins of autoantibodies Current Opinion in Immunology. 1: 697-700. PMID 2679722 DOI: 10.1016/0952-7915(89)90045-9  0.449
1987 Shlomchik MJ, Marshak-Rothstein A, Wolfowicz CB, Rothstein TL, Weigert MG. The role of clonal selection and somatic mutation in autoimmunity. Nature. 328: 805-11. PMID 3498121 DOI: 10.1038/328805A0  0.377
1985 Weissman D, Rothstein TL, Marshak-Rothstein A. A rapid method for comparing monoclonal antibodies by limited proteolysis and electrophoresis Hybridoma. 4: 329-339. PMID 3905580 DOI: 10.1089/Hyb.1985.4.329  0.454
1985 Weissman D, Rothstein T, Marshak-Rothstein A. Growing xenogenic monoclonals in murine ascites Federation Proceedings. 44.  0.412
1984 Rothstein TL, Miller RA, Parker DJ, Kelly E, Vastola AP, Marshak-Rothstein A. Induction of idiotope suppression in the anti-azophenylarsonate response of T-depleted A/J mice. The Journal of Experimental Medicine. 159: 1283-8. PMID 6608575 DOI: 10.1084/Jem.159.4.1283  0.444
1984 Groopman JD, Trudel LJ, Donahue PR, Marshak-Rothstein A, Wogan GN. High-affinity monoclonal antibodies for aflatoxins and their application to solid-phase immunoassays Proceedings of the National Academy of Sciences of the United States of America. 81: 7728-7731. PMID 6440143 DOI: 10.1073/Pnas.81.24.7728  0.374
1984 McCormack JE, Kent RB, Pepe VH, Dean M, Marshak-Rothstein A, Sonenshein GE. Immune regulation of the c-myc oncogene in a murine B lymphoma. Current Topics in Microbiology and Immunology. 113: 127-32. PMID 6332712 DOI: 10.1007/978-3-642-69860-6_23  0.313
1984 McCormack JE, Pepe VH, Kent RB, Dean M, Marshak-Rothstein A, Sonenshein GE. Specific regulation of c-myc oncogene expression in a murine B-cell lymphoma. Proceedings of the National Academy of Sciences of the United States of America. 81: 5546-50. PMID 6206500 DOI: 10.1073/Pnas.81.17.5546  0.365
1982 Siekevitz M, Gefter ML, Brodeur P, Riblet R, Marshak-Rothstein A. The genetic basis of antibody production: The dominant anti-arsonate idiotype response of the strain A mouse European Journal of Immunology. 12: 1023-1032. PMID 6186498 DOI: 10.1002/Eji.1830121208  0.331
1981 Marshak-Rothstein A, Margoliess MN, Benedetto JD, Gefter ML. Two structurally distinct and independently regulated idiotypic families associated with the A/J response to azophenylarsonate European Journal of Immunology. 11: 565-572. PMID 7286063 DOI: 10.1002/Eji.1830110709  0.356
1980 Marshak-Rothstein A, Siekevitz M, Margolies MN, Mudgett-Hunter M, Gefter ML. Hybridoma proteins expressing the predominant idiotype of the antiazophenylarsonate response of A/J mice Proceedings of the National Academy of Sciences of the United States of America. 77: 1120-1124. PMID 6767242 DOI: 10.1073/Pnas.77.2.1120  0.328
1979 Marshak-Rothstein A, Fink P, Gridley T, Raulet DH, Bevan MJ, Gefter ML. Properties and applications of monoclonal antibodies directed against determinants of the THY-1 locus Journal of Immunology. 122: 2491-2497. PMID 87465  0.324
1979 Sieck T, Marshak-Rothstein A, Wilson DB. Studies of the MHC-linked "CT" alloantigenic systems in rats - I. neither an SD nor an LD gene product Immunogenetics. 9: 165-172. DOI: 10.1007/Bf01570407  0.542
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