Yasuko Rikihisa - Publications

Affiliations: 
Ohio State University, Columbus, Columbus, OH 
Area:
Molecular Biology, Microbiology Biology

219 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Huang W, Lin M, Rikihisa Y. Rab27a via its effector JFC1 localizes to Anaplasma inclusions and promotes Anaplasma proliferation in leukocytes. Microbes and Infection. 105278. PMID 38110148 DOI: 10.1016/j.micinf.2023.105278  0.596
2023 Lin M, Koley A, Zhang W, Pei D, Rikihisa Y. Inhibition of infection by cell-permeable macrocyclic peptides that bind type IV secretion effector Etf-1. Pnas Nexus. 2: pgad017. PMID 36874272 DOI: 10.1093/pnasnexus/pgad017  0.564
2022 Budachetri K, Lin M, Chien RC, Zhang W, Brock GN, Rikihisa Y. Efficacy and Immune Correlates of OMP-1B and VirB2-4 Vaccines for Protection of Dogs from Tick Transmission of Ehrlichia chaffeensis. Mbio. 13: e0214022. PMID 36342170 DOI: 10.1128/mbio.02140-22  0.569
2022 Budachetri K, Lin M, Yan Q, Chien RC, Hostnik LD, Haanen G, Leclère M, Waybright W, Baird JD, Arroyo LG, Rikihisa Y. Real-Time PCR Differential Detection of and in Cases of Potomac Horse Fever. Journal of Clinical Microbiology. e0025022. PMID 35695520 DOI: 10.1128/jcm.00250-22  0.546
2021 Huang W, Xiong Q, Lin M, Rikihisa Y. Anaplasma phagocytophilum Hijacks Flotillin and NPC1 Complex To Acquire Intracellular Cholesterol for Proliferation, Which Can Be Inhibited with Ezetimibe. Mbio. e0229921. PMID 34544283 DOI: 10.1128/mBio.02299-21  0.682
2021 Arroyo LG, Moore A, Bedford S, Gomez DE, Teymournejad O, Xiong Q, Budachetri K, Bekebrede H, Rikihisa Y, Baird JD. Potomac horse fever in Ontario: Clinical, geographic, and diagnostic aspects. The Canadian Veterinary Journal = La Revue Veterinaire Canadienne. 62: 622-628. PMID 34219771  0.51
2021 Yan Q, Zhang W, Lin M, Teymournejad O, Budachetri K, Lakritz J, Rikihisa Y. Iron robbery by intracellular pathogen via bacterial effector-induced ferritinophagy. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 34074773 DOI: 10.1073/pnas.2026598118  0.564
2021 Zhang W, Lin M, Yan Q, Budachetri K, Hou L, Sahni A, Liu H, Han NC, Lakritz J, Pei D, Rikihisa Y. An intracellular nanobody targeting T4SS effector inhibits infection. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 33903242 DOI: 10.1073/pnas.2024102118  0.599
2021 Lin M, Xiong Q, Chung M, Daugherty SC, Nagaraj S, Sengamalay N, Ott S, Godinez A, Tallon LJ, Sadzewicz L, Fraser C, Dunning Hotopp JC, Rikihisa Y. Comparative Analysis of Genome of Ehrlichia sp. HF, a Model Bacterium to Study Fatal Human Ehrlichiosis. Bmc Genomics. 22: 11. PMID 33407096 DOI: 10.1186/s12864-020-07309-z  0.683
2020 Budachetri K, Teymournejad O, Lin M, Yan Q, Mestres-Villanueva M, Brock GN, Rikihisa Y. An Entry-Triggering Protein of Is a New Vaccine Candidate against Tick-Borne Human Monocytic Ehrlichiosis. Mbio. 11. PMID 32723916 DOI: 10.1128/Mbio.00895-20  0.603
2020 Teymournejad O, Lin M, Bekebrede H, Kamr A, Toribio RE, Arroyo LG, Baird JD, Rikihisa Y. Erratum for Teymournejad et al., "Isolation and Molecular Analysis of a Novel Species That Causes Potomac Horse Fever". Mbio. 11. PMID 32317326 DOI: 10.1128/Mbio.00774-20  0.543
2020 Teymournejad O, Rikihisa Y. Ehrlichia chaffeensis Uses an Invasin To Suppress Reactive Oxygen Species Generation by Macrophages via CD147-Dependent Inhibition of Vav1 To Block Rac1 Activation. Mbio. 11. PMID 32317318 DOI: 10.1128/Mbio.00267-20  0.333
2020 Lin M, Grandinetti G, Hartnell LM, Bliss D, Subramaniam S, Rikihisa Y. Host membrane lipids are trafficked to membranes of intravacuolar bacterium . Proceedings of the National Academy of Sciences of the United States of America. PMID 32193339 DOI: 10.1073/Pnas.1921619117  0.626
2020 Bekebrede H, Lin M, Teymournejad O, Rikihisa Y. Discovery of Virulence Genes of Obligatory Intracellular Bacteria by Random Mutagenesis. Frontiers in Cellular and Infection Microbiology. 10: 2. PMID 32117791 DOI: 10.3389/Fcimb.2020.00002  0.638
2020 Teymournejad O, Lin M, Bekebrede H, Kamr A, Toribio RE, Arroyo LG, Baird JD, Rikihisa Y. Isolation and Molecular Analysis of a Novel Species That Causes Potomac Horse Fever. Mbio. 11. PMID 32098825 DOI: 10.1128/Mbio.03429-19  0.612
2019 Xiong Q, Lin M, Huang W, Rikihisa Y. Infection by Anaplasma phagocytophilum Requires Recruitment of Low-Density Lipoprotein Cholesterol by Flotillins. Mbio. 10. PMID 30914515 DOI: 10.1128/Mbio.02783-18  0.702
2018 Yan Q, Lin M, Huang W, Teymournejad O, Johnson JM, Hays FA, Liang Z, Li G, Rikihisa Y. type IV secretion system effector Etf-2 binds to active RAB5 and delays endosome maturation. Proceedings of the National Academy of Sciences of the United States of America. PMID 30181274 DOI: 10.1073/Pnas.1806904115  0.615
2017 Rikihisa Y. Role and Function of the Type IV Secretion System in Anaplasma and Ehrlichia Species. Current Topics in Microbiology and Immunology. 413: 297-321. PMID 29536364 DOI: 10.1007/978-3-319-75241-9_12  0.461
2017 Teymournejad O, Lin M, Rikihisa Y. Ehrlichia chaffeensis and Its Invasin EtpE Block Reactive Oxygen Species Generation by Macrophages in a DNase X-Dependent Manner. Mbio. 8. PMID 29162709 DOI: 10.1128/Mbio.01551-17  0.635
2017 Pritt BS, Allerdice MEJ, Sloan LM, Paddock CD, Munderloh UG, Rikihisa Y, Tajima T, Paskewitz SM, Neitzel DF, Hoang Johnson DK, Schiffman E, Davis JP, Goldsmith CS, Nelson CM, Karpathy SE. Proposal to reclassify Ehrlichia muris as Ehrlichia muris subsp. muris subsp. nov. and description of Ehrlichia muris subsp. eauclairensis subsp. nov., a newly recognized tick-borne pathogen of humans. International Journal of Systematic and Evolutionary Microbiology. PMID 28699575 DOI: 10.1099/Ijsem.0.001896  0.376
2017 Rikihisa Y. Subversion of RAB5-Regulated Autophagy by the Intracellular Pathogen Ehrlichia chaffeensis. Small Gtpases. 0. PMID 28650718 DOI: 10.1080/21541248.2017.1332506  0.371
2017 Sharma P, Teymournejad O, Rikihisa Y. Peptide Nucleic Acid Knockdown and Intra-host Cell Complementation of Ehrlichia Type IV Secretion System Effector. Frontiers in Cellular and Infection Microbiology. 7: 228. PMID 28638803 DOI: 10.3389/Fcimb.2017.00228  0.455
2017 Lin M, Bachman K, Cheng Z, Daugherty SC, Nagaraj S, Sengamalay N, Ott S, Godinez A, Tallon LJ, Sadzewicz L, Fraser C, Dunning Hotopp JC, Rikihisa Y. Analysis of complete genome sequence and major surface antigens of Neorickettsia helminthoeca, causative agent of salmon poisoning disease. Microbial Biotechnology. PMID 28585301 DOI: 10.1111/1751-7915.12731  0.642
2016 Kumar N, Lin M, Zhao X, Ott S, Santana-Cruz I, Daugherty S, Rikihisa Y, Sadzewicz L, Tallon LJ, Fraser CM, Dunning Hotopp JC. Efficient Enrichment of Bacterial mRNA from Host-Bacteria Total RNA Samples. Scientific Reports. 6: 34850. PMID 27713560 DOI: 10.1038/Srep34850  0.609
2016 Lin M, Liu H, Xiong Q, Niu H, Cheng Z, Yamamoto A, Rikihisa Y. Ehrlichia secretes Etf-1 to induce autophagy and capture nutrients for its growth through RAB5 and class III phosphatidylinositol 3-kinase. Autophagy. 0. PMID 27541856 DOI: 10.1080/15548627.2016.1217369  0.731
2016 Xiong Q, Bekebrede H, Sharma P, Arroyo LG, Baird JD, Rikihisa Y. Molecular Analysis of Neorickettsia risticii, the Trematode-borne Agent of Potomac Horse Fever, Culture Isolated from a Canadian Horse. Applied and Environmental Microbiology. PMID 27474720 DOI: 10.1128/Aem.01366-16  0.596
2016 Lai TH, Parraga ME, Alvarez E, Rikihisa Y. Anaplasma platys Immunoblot Test Using Major Surface Antigens. Vector Borne and Zoonotic Diseases (Larchmont, N.Y.). PMID 27327629 DOI: 10.1089/Vbz.2016.1964  0.423
2016 Greiman SE, Rikihisa Y, Cain J, Vaughan JA, Tkach VV. GERMS WITHIN WORMS: LOCALIZATION OF NEORICKETTSIA SP. WITHIN LIFE CYCLE STAGES OF DIGENEAN PLAGIORCHIS ELEGANS. Applied and Environmental Microbiology. PMID 26873314 DOI: 10.1128/Aem.04098-15  0.38
2016 Ge Y, Yin H, Rikihisa Y, Pan W, Yin H. Molecular Detection of Tick-Borne Rickettsiales in Goats and Sheep from Southeastern China. Vector Borne and Zoonotic Diseases (Larchmont, N.Y.). PMID 26872274 DOI: 10.1089/Vbz.2015.1884  0.354
2016 Klionsky DJ, Abdelmohsen K, Abe A, Abedin MJ, Abeliovich H, Acevedo Arozena A, Adachi H, Adams CM, Adams PD, Adeli K, Adhihetty PJ, Adler SG, Agam G, Agarwal R, Aghi MK, ... ... Rikihisa Y, et al. Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). Autophagy. 12: 1-222. PMID 26799652 DOI: 10.1080/15548627.2015.1100356  0.646
2015 Mohan Kumar D, Lin M, Xiong Q, Webber MJ, Kural C, Rikihisa Y. EtpE Binding to DNase X Induces Ehrlichial Entry via CD147 and hnRNP-K Recruitment, Followed by Mobilization of N-WASP and Actin. Mbio. 6. PMID 26530384 DOI: 10.1128/Mbio.01541-15  0.721
2015 Rikihisa Y. Molecular Pathogenesis of Ehrlichia chaffeensis Infection. Annual Review of Microbiology. 69: 283-304. PMID 26488275 DOI: 10.1146/Annurev-Micro-091014-104411  0.426
2015 Cheng Z, Lin M, Rikihisa Y. Erratum for Cheng et al., Ehrlichia chaffeensis proliferation begins with NtrY/NtrX and PutA/GlnA upregulation and CtrA degradation induced by proline and glutamine uptake. Mbio. 6: e00242. PMID 25784699 DOI: 10.1128/Mbio.00242-15  0.531
2014 Cheng Z, Lin M, Rikihisa Y. Ehrlichia chaffeensis proliferation begins with NtrY/NtrX and PutA/GlnA upregulation and CtrA degradation induced by proline and glutamine uptake. Mbio. 5: e02141. PMID 25425236 DOI: 10.1128/Mbio.02141-14  0.651
2014 Niu H, Rikihisa Y. Investigating interference with apoptosis induction by bacterial proteins. Methods in Molecular Biology (Clifton, N.J.). 1197: 169-84. PMID 25172281 DOI: 10.1007/978-1-4939-1261-2_10  0.363
2013 Mohan Kumar D, Yamaguchi M, Miura K, Lin M, Los M, Coy JF, Rikihisa Y. Ehrlichia chaffeensis uses its surface protein EtpE to bind GPI-anchored protein DNase X and trigger entry into mammalian cells. Plos Pathogens. 9: e1003666. PMID 24098122 DOI: 10.1371/Journal.Ppat.1003666  0.644
2013 Wang P, Dadhwal P, Cheng Z, Zianni MR, Rikihisa Y, Liang FT, Li X. Borrelia burgdorferi oxidative stress regulator BosR directly represses lipoproteins primarily expressed in the tick during mammalian infection. Molecular Microbiology. 89: 1140-53. PMID 23869590 DOI: 10.1111/Mmi.12337  0.339
2013 Niu H, Rikihisa Y. Ats-1: a novel bacterial molecule that links autophagy to bacterial nutrition. Autophagy. 9: 787-8. PMID 23388398 DOI: 10.4161/Auto.23693  0.39
2012 Niu H, Xiong Q, Yamamoto A, Hayashi-Nishino M, Rikihisa Y. Autophagosomes induced by a bacterial Beclin 1 binding protein facilitate obligatory intracellular infection. Proceedings of the National Academy of Sciences of the United States of America. 109: 20800-7. PMID 23197835 DOI: 10.1073/Pnas.1218674109  0.634
2012 Rahman MA, Cheng Z, Matsuo J, Rikihisa Y. Penicillin-binding protein of Ehrlichia chaffeensis: cytokine induction through MyD88-dependent pathway. The Journal of Infectious Diseases. 206: 110-6. PMID 22539814 DOI: 10.1093/Infdis/Jis313  0.403
2012 Liu H, Bao W, Lin M, Niu H, Rikihisa Y. Ehrlichia type IV secretion effector ECH0825 is translocated to mitochondria and curbs ROS and apoptosis by upregulating host MnSOD. Cellular Microbiology. 14: 1037-50. PMID 22348527 DOI: 10.1111/J.1462-5822.2012.01775.X  0.651
2012 Xiong Q, Rikihisa Y. Subversion of NPC1 pathway of cholesterol transport by Anaplasma phagocytophilum. Cellular Microbiology. 14: 560-76. PMID 22212234 DOI: 10.1111/J.1462-5822.2011.01742.X  0.598
2011 Cheng Z, Miura K, Popov VL, Kumagai Y, Rikihisa Y. Insights into the CtrA regulon in development of stress resistance in obligatory intracellular pathogen Ehrlichia chaffeensis. Molecular Microbiology. 82: 1217-34. PMID 22014113 DOI: 10.1111/J.1365-2958.2011.07885.X  0.374
2011 Kumagai Y, Matsuo J, Cheng Z, Hayakawa Y, Rikihisa Y. Cyclic dimeric GMP signaling regulates intracellular aggregation, sessility, and growth of Ehrlichia chaffeensis. Infection and Immunity. 79: 3905-12. PMID 21788390 DOI: 10.1128/Iai.05320-11  0.41
2011 Rikihisa Y. Mechanisms of obligatory intracellular infection with Anaplasma phagocytophilum. Clinical Microbiology Reviews. 24: 469-89. PMID 21734244 DOI: 10.1128/Cmr.00064-10  0.427
2011 Lin M, Kikuchi T, Brewer HM, Norbeck AD, Rikihisa Y. Global proteomic analysis of two tick-borne emerging zoonotic agents: anaplasma phagocytophilum and ehrlichia chaffeensis. Frontiers in Microbiology. 2: 24. PMID 21687416 DOI: 10.3389/Fmicb.2011.00024  0.666
2011 Gibson KE, Pastenkos G, Moesta S, Rikihisa Y. Neorickettsia risticii surface-exposed proteins: proteomics identification, recognition by naturally-infected horses, and strain variations. Veterinary Research. 42: 71. PMID 21635728 DOI: 10.1186/1297-9716-42-71  0.372
2011 Lai TH, Orellana NG, Yuasa Y, Rikihisa Y. Cloning of the major outer membrane protein expression locus in Anaplasma platys and seroreactivity of a species-specific antigen. Journal of Bacteriology. 193: 2924-30. PMID 21498646 DOI: 10.1128/Jb.00082-11  0.42
2011 Ge Y, Rikihisa Y. Subversion of host cell signaling by Orientia tsutsugamushi. Microbes and Infection / Institut Pasteur. 13: 638-48. PMID 21458586 DOI: 10.1016/J.Micinf.2011.03.003  0.301
2011 Xiong Q, Rikihisa Y. The prenylation inhibitor manumycin A reduces the viability of Anaplasma phagocytophilum. Journal of Medical Microbiology. 60: 744-9. PMID 21349982 DOI: 10.1099/Jmm.0.029231-0  0.625
2010 O'Connor TP, Saucier JM, Daniluk D, Stillman BA, Krah R, Rikihisa Y, Xiong Q, Yabsley MJ, Adams DS, Diniz PP, Breitschwerdt EB, Gaunt SD, Chandrashekar R. Evaluation of peptide- and recombinant protein-based assays for detection of anti-Ehrlichia ewingii antibodies in experimentally and naturally infected dogs. [corrected] American Journal of Veterinary Research. 71: 1195-200. PMID 20919906 DOI: 10.2460/Ajvr.71.10.1195  0.642
2010 Gibson K, Kumagai Y, Rikihisa Y. Proteomic analysis of Neorickettsia sennetsu surface-exposed proteins and porin activity of the major surface protein P51. Journal of Bacteriology. 192: 5898-905. PMID 20833807 DOI: 10.1128/Jb.00632-10  0.352
2010 Rikihisa Y, Lin M, Niu H. Type IV secretion in the obligatory intracellular bacterium Anaplasma phagocytophilum. Cellular Microbiology. 12: 1213-21. PMID 20670295 DOI: 10.1111/J.1462-5822.2010.01500.X  0.641
2010 Kumagai Y, Matsuo J, Hayakawa Y, Rikihisa Y. Cyclic di-GMP signaling regulates invasion by Ehrlichia chaffeensis of human monocytes. Journal of Bacteriology. 192: 4122-33. PMID 20562302 DOI: 10.1128/Jb.00132-10  0.391
2010 Rikihisa Y. Anaplasma phagocytophilum and Ehrlichia chaffeensis: subversive manipulators of host cells. Nature Reviews. Microbiology. 8: 328-39. PMID 20372158 DOI: 10.1038/Nrmicro2318  0.389
2010 Niu H, Kozjak-Pavlovic V, Rudel T, Rikihisa Y. Anaplasma phagocytophilum Ats-1 is imported into host cell mitochondria and interferes with apoptosis induction. Plos Pathogens. 6: e1000774. PMID 20174550 DOI: 10.1371/Journal.Ppat.1000774  0.392
2010 Rikihisa Y, Lin M. Anaplasma phagocytophilum and Ehrlichia chaffeensis type IV secretion and Ank proteins. Current Opinion in Microbiology. 13: 59-66. PMID 20053580 DOI: 10.1016/J.Mib.2009.12.008  0.637
2010 Rikihisa Y. Molecular events involved in cellular invasion by Ehrlichia chaffeensis and Anaplasma phagocytophilum. Veterinary Parasitology. 167: 155-66. PMID 19836896 DOI: 10.1016/J.Vetpar.2009.09.017  0.399
2009 Kawahara M, Tajima T, Torii H, Yabutani M, Ishii J, Harasawa M, Isogai E, Rikihisa Y. Ehrlichia chaffeensis infection of sika deer, Japan. Emerging Infectious Diseases. 15: 1991-3. PMID 19961683 DOI: 10.3201/Eid1512.081667  0.396
2009 Lin M, Zhang C, Gibson K, Rikihisa Y. Analysis of complete genome sequence of Neorickettsia risticii: causative agent of Potomac horse fever. Nucleic Acids Research. 37: 6076-91. PMID 19661282 DOI: 10.1093/Nar/Gkp642  0.617
2009 Unver A, Rikihisa Y, Karaman M, Ozen H. An acute severe ehrlichiosis in a dog experimentally infected with a new virulent strain of Ehrlichia canis Clinical Microbiology and Infection. 15: 59-61. PMID 19548986 DOI: 10.1111/J.1469-0691.2008.02634.X  0.689
2009 Rikihisa Y, Lin M, Niu H, Cheng Z. Type IV secretion system of Anaplasma phagocytophilum and Ehrlichia chaffeensis. Annals of the New York Academy of Sciences. 1166: 106-11. PMID 19538269 DOI: 10.1111/J.1749-6632.2009.04527.X  0.627
2009 Gieg J, Rikihisa Y, Wellman M. Diagnosis of Ehrlichia ewingii infection by PCR in a puppy from Ohio. Veterinary Clinical Pathology / American Society For Veterinary Clinical Pathology. 38: 406-10. PMID 19351337 DOI: 10.1111/J.1939-165X.2009.00131.X  0.339
2009 Xiong Q, Lin M, Rikihisa Y. Cholesterol-dependent anaplasma phagocytophilum exploits the low-density lipoprotein uptake pathway. Plos Pathogens. 5: e1000329. PMID 19283084 DOI: 10.1371/Journal.Ppat.1000329  0.711
2009 Miura K, Rikihisa Y. Liver transcriptome profiles associated with strain-specific Ehrlichia chaffeensis-induced hepatitis in SCID mice. Infection and Immunity. 77: 245-54. PMID 19001077 DOI: 10.1128/Iai.00979-08  0.353
2009 Lai TH, Kumagai Y, Hyodo M, Hayakawa Y, Rikihisa Y. The Anaplasma phagocytophilum PleC histidine kinase and PleD diguanylate cyclase two-component system and role of cyclic Di-GMP in host cell infection. Journal of Bacteriology. 191: 693-700. PMID 18978058 DOI: 10.1128/Jb.01218-08  0.347
2009 Bao W, Kumagai Y, Niu H, Yamaguchi M, Miura K, Rikihisa Y. Four VirB6 paralogs and VirB9 are expressed and interact in Ehrlichia chaffeensis-containing vacuoles. Journal of Bacteriology. 191: 278-86. PMID 18952796 DOI: 10.1128/Jb.01031-08  0.432
2008 Schaefer JJ, Kahn J, Needham GR, Rikihisa Y, Ewing SA, Stich RW. Antibiotic clearance of Ehrlichia canis from dogs infected by intravenous inoculation of carrier blood. Annals of the New York Academy of Sciences. 1149: 263-9. PMID 19120226 DOI: 10.1196/Annals.1428.087  0.393
2008 Delos Santos JR, Oglesbee M, Rikihisa Y, Stich RW. Pathologic evidence of ehrlichiosis in calves inoculated with Ehrlichia chaffeensis. Annals of the New York Academy of Sciences. 1149: 103-6. PMID 19120184 DOI: 10.1196/Annals.1428.068  0.344
2008 Huang H, Lin M, Wang X, Kikuchi T, Mottaz H, Norbeck A, Rikihisa Y. Proteomic analysis of and immune responses to Ehrlichia chaffeensis lipoproteins. Infection and Immunity. 76: 3405-14. PMID 18490460 DOI: 10.1128/Iai.00056-08  0.716
2008 Xiong Q, Bao W, Ge Y, Rikihisa Y. Ehrlichia ewingii infection delays spontaneous neutrophil apoptosis through stabilization of mitochondria. The Journal of Infectious Diseases. 197: 1110-8. PMID 18462160 DOI: 10.1086/533457  0.628
2008 Gibson KE, Rikihisa Y. Molecular link of different stages of the trematode host of Neorickettsia risticii to Acanthatrium oregonense. Environmental Microbiology. 10: 2064-73. PMID 18422641 DOI: 10.1111/J.1462-2920.2008.01625.X  0.331
2008 Kumagai Y, Huang H, Rikihisa Y. Expression and porin activity of P28 and OMP-1F during intracellular Ehrlichia chaffeensis development. Journal of Bacteriology. 190: 3597-605. PMID 18359808 DOI: 10.1128/Jb.02017-07  0.351
2008 Cheng Z, Wang X, Rikihisa Y. Regulation of type IV secretion apparatus genes during Ehrlichia chaffeensis intracellular development by a previously unidentified protein. Journal of Bacteriology. 190: 2096-105. PMID 18192398 DOI: 10.1128/Jb.01813-07  0.588
2008 Zhang C, Xiong Q, Kikuchi T, Rikihisa Y. Identification of 19 polymorphic major outer membrane protein genes and their immunogenic peptides in Ehrlichia ewingii for use in a serodiagnostic assay. Clinical and Vaccine Immunology : Cvi. 15: 402-11. PMID 18094116 DOI: 10.1128/Cvi.00366-07  0.643
2008 Niu H, Yamaguchi M, Rikihisa Y. Subversion of cellular autophagy by Anaplasma phagocytophilum. Cellular Microbiology. 10: 593-605. PMID 17979984 DOI: 10.1111/J.1462-5822.2007.01068.X  0.403
2007 delos Santos JR, Boughan K, Bremer WG, Rizzo B, Schaefer JJ, Rikihisa Y, Needham GR, Capitini LA, Anderson DE, Oglesbee M, Ewing SA, Stich RW. Experimental infection of dairy calves with Ehrlichia chaffeensis. Journal of Medical Microbiology. 56: 1660-8. PMID 18033836 DOI: 10.1099/Jmm.0.47427-0  0.441
2007 Wang X, Cheng Z, Zhang C, Kikuchi T, Rikihisa Y. Anaplasma phagocytophilum p44 mRNA expression is differentially regulated in mammalian and tick host cells: involvement of the DNA binding protein ApxR. Journal of Bacteriology. 189: 8651-9. PMID 17905983 DOI: 10.1128/Jb.00881-07  0.614
2007 Ge Y, Rikihisa Y. Identification of novel surface proteins of Anaplasma phagocytophilum by affinity purification and proteomics. Journal of Bacteriology. 189: 7819-28. PMID 17766422 DOI: 10.1128/Jb.00866-07  0.372
2007 Schaefer JJ, Needham GR, Bremer WG, Rikihisa Y, Ewing SA, Stich RW. Tick acquisition of Ehrlichia canis from dogs treated with doxycycline hyclate. Antimicrobial Agents and Chemotherapy. 51: 3394-6. PMID 17606682 DOI: 10.1128/Aac.00358-07  0.33
2007 Lin M, den Dulk-Ras A, Hooykaas PJ, Rikihisa Y. Anaplasma phagocytophilum AnkA secreted by type IV secretion system is tyrosine phosphorylated by Abl-1 to facilitate infection. Cellular Microbiology. 9: 2644-57. PMID 17587335 DOI: 10.1111/J.1462-5822.2007.00985.X  0.654
2007 Ge Y, Rikihisa Y. Surface-exposed proteins of Ehrlichia chaffeensis. Infection and Immunity. 75: 3833-41. PMID 17517859 DOI: 10.1128/Iai.00188-07  0.371
2007 Wang X, Kikuchi T, Rikihisa Y. Proteomic identification of a novel Anaplasma phagocytophilum DNA binding protein that regulates a putative transcription factor. Journal of Bacteriology. 189: 4880-6. PMID 17483233 DOI: 10.1128/Jb.00318-07  0.551
2007 Miura K, Rikihisa Y. Virulence potential of Ehrlichia chaffeensis strains of distinct genome sequences. Infection and Immunity. 75: 3604-13. PMID 17438035 DOI: 10.1128/Iai.02028-06  0.354
2007 Xiong Q, Wang X, Rikihisa Y. High-cholesterol diet facilitates Anaplasma phagocytophilum infection and up-regulates macrophage inflammatory protein-2 and CXCR2 expression in apolipoprotein E-deficient mice. The Journal of Infectious Diseases. 195: 1497-503. PMID 17436230 DOI: 10.1086/514819  0.68
2007 Huang H, Wang X, Kikuchi T, Kumagai Y, Rikihisa Y. Porin activity of Anaplasma phagocytophilum outer membrane fraction and purified P44. Journal of Bacteriology. 189: 1998-2006. PMID 17172334 DOI: 10.1128/Jb.01548-06  0.553
2007 Lin M, Rikihisa Y. Degradation of p22phox and inhibition of superoxide generation by Ehrlichia chaffeensis in human monocytes. Cellular Microbiology. 9: 861-74. PMID 17087735 DOI: 10.1111/J.1462-5822.2006.00835.X  0.656
2006 Unver A, Huang H, Rikihisa Y. Cytokine gene expression by peripheral blood leukocytes in dogs experimentally infected with a new virulent strain of Ehrlichia canis. Annals of the New York Academy of Sciences. 1078: 482-6. PMID 17114759 DOI: 10.1196/Annals.1374.090  0.653
2006 Rikihisa Y. New findings on members of the family Anaplasmataceae of veterinary importance. Annals of the New York Academy of Sciences. 1078: 438-45. PMID 17114752 DOI: 10.1196/Annals.1374.083  0.343
2006 Perez M, Bodor M, Zhang C, Xiong Q, Xiong Q, Rikihisa Y. Human infection with Ehrlichia canis accompanied by clinical signs in Venezuela. Annals of the New York Academy of Sciences. 1078: 110-7. PMID 17114689 DOI: 10.1196/Annals.1374.016  0.618
2006 Kumagai Y, Cheng Z, Lin M, Rikihisa Y. Biochemical activities of three pairs of Ehrlichia chaffeensis two-component regulatory system proteins involved in inhibition of lysosomal fusion. Infection and Immunity. 74: 5014-22. PMID 16926392 DOI: 10.1128/Iai.00735-06  0.643
2006 Ge Y, Rikihisa Y. Anaplasma phagocytophilum delays spontaneous human neutrophil apoptosis by modulation of multiple apoptotic pathways. Cellular Microbiology. 8: 1406-16. PMID 16922860 DOI: 10.1111/J.1462-5822.2006.00720.X  0.305
2006 Cheng Z, Kumagai Y, Lin M, Zhang C, Rikihisa Y. Intra-leukocyte expression of two-component systems in Ehrlichia chaffeensis and Anaplasma phagocytophilum and effects of the histidine kinase inhibitor closantel. Cellular Microbiology. 8: 1241-52. PMID 16882029 DOI: 10.1111/J.1462-5822.2006.00704.X  0.673
2006 Lin Q, Zhang C, Rikihisa Y. Analysis of involvement of the RecF pathway in p44 recombination in Anaplasma phagocytophilum and in Escherichia coli by using a plasmid carrying the p44 expression and p44 donor loci. Infection and Immunity. 74: 2052-62. PMID 16552034 DOI: 10.1128/Iai.74.4.2052-2062.2006  0.565
2006 Wang X, Kikuchi T, Rikihisa Y. Two monoclonal antibodies with defined epitopes of P44 major surface proteins neutralize Anaplasma phagocytophilum by distinct mechanisms. Infection and Immunity. 74: 1873-82. PMID 16495562 DOI: 10.1128/Iai.74.3.1873-1882.2006  0.607
2006 Dunning Hotopp JC, Lin M, Madupu R, Crabtree J, Angiuoli SV, Eisen JA, Eisen J, Seshadri R, Ren Q, Wu M, Utterback TR, Smith S, Lewis M, Khouri H, Zhang C, ... ... Rikihisa Y, et al. Comparative genomics of emerging human ehrlichiosis agents. Plos Genetics. 2: e21. PMID 16482227 DOI: 10.1371/Journal.Pgen.0020021  0.784
2006 Niu H, Rikihisa Y, Yamaguchi M, Ohashi N. Differential expression of VirB9 and VirB6 during the life cycle of Anaplasma phagocytophilum in human leucocytes is associated with differential binding and avoidance of lysosome pathway. Cellular Microbiology. 8: 523-34. PMID 16469062 DOI: 10.1111/J.1462-5822.2005.00643.X  0.427
2006 Kawahara M, Rikihisa Y, Lin Q, Isogai E, Tahara K, Itagaki A, Hiramitsu Y, Tajima T. Novel genetic variants of Anaplasma phagocytophilum, Anaplasma bovis, Anaplasma centrale, and a novel Ehrlichia sp. in wild deer and ticks on two major islands in Japan. Applied and Environmental Microbiology. 72: 1102-9. PMID 16461655 DOI: 10.1128/Aem.72.2.1102-1109.2006  0.564
2006 Rikihisa Y. Ehrlichia subversion of host innate responses. Current Opinion in Microbiology. 9: 95-101. PMID 16406779 DOI: 10.1016/J.Mib.2005.12.003  0.39
2006 Dunning Hotopp JC, Lin M, Madupu R, Crabtree J, Angiuoli SV, Eisen JA, Seshadri R, Ren Q, Wu M, Utterback TR, Smith S, Lewis M, Khouri H, Zhang C, Niu H, ... ... Rikihisa Y, et al. Correction: Comparative Genomics of Emerging Human Ehrlichiosis Agents Plos Genetics. 2: e213. DOI: 10.1371/Journal.Pgen.0020213  0.73
2005 Tajima T, Rikihisa Y. Cytokine responses in dogs infected with Ehrlichia canis Oklahoma strain. Annals of the New York Academy of Sciences. 1063: 429-32. PMID 16481554 DOI: 10.1196/Annals.1355.078  0.412
2005 Unver A, Rikihisa Y, Borku K, Ozkanlar Y, Hanedan B. Molecular detection and characterization of Ehrlichia canis from dogs in Turkey. Berliner Und MüNchener TieräRztliche Wochenschrift. 118: 300-4. PMID 16048040  0.682
2005 Lin Q, Rikihisa Y. Establishment of cloned Anaplasma phagocytophilum and analysis of p44 gene conversion within an infected horse and infected SCID mice. Infection and Immunity. 73: 5106-14. PMID 16041027 DOI: 10.1128/Iai.73.8.5106-5114.2005  0.58
2005 Bremer WG, Schaefer JJ, Wagner ER, Ewing SA, Rikihisa Y, Needham GR, Jittapalapong S, Moore DL, Stich RW. Transstadial and intrastadial experimental transmission of Ehrlichia canis by male Rhipicephalus sanguineus. Veterinary Parasitology. 131: 95-105. PMID 15941624 DOI: 10.1016/J.Vetpar.2005.04.030  0.376
2005 Gibson KE, Rikihisa Y, Zhang C, Martin C. Neorickettsia risticii is vertically transmitted in the trematode Acanthatrium oregonense and horizontally transmitted to bats. Environmental Microbiology. 7: 203-12. PMID 15658987 DOI: 10.1111/J.1462-2920.2004.00683.X  0.309
2005 Ge Y, Yoshiie K, Kuribayashi F, Lin M, Rikihisa Y. Anaplasma phagocytophilum inhibits human neutrophil apoptosis via upregulation of bfl-1, maintenance of mitochondrial membrane potential and prevention of caspase 3 activation. Cellular Microbiology. 7: 29-38. PMID 15617521 DOI: 10.1111/J.1462-5822.2004.00427.X  0.618
2005 Huang H, Unver A, Perez MJ, Orellana NG, Rikihisa Y. Prevalence and molecular analysis of Anaplasma platys in dogs in Lara, Venezuela Brazilian Journal of Microbiology. 36: 211-216. DOI: 10.1590/S1517-83822005000300002  0.67
2004 Wang X, Rikihisa Y, Lai TH, Kumagai Y, Zhi N, Reed SM. Rapid sequential changeover of expressed p44 genes during the acute phase of Anaplasma phagocytophilum infection in horses. Infection and Immunity. 72: 6852-9. PMID 15557606 DOI: 10.1128/Iai.72.12.6852-6859.2004  0.721
2004 Kawahara M, Rikihisa Y, Isogai E, Takahashi M, Misumi H, Suto C, Shibata S, Zhang C, Tsuji M. Ultrastructure and phylogenetic analysis of 'Candidatus Neoehrlichia mikurensis' in the family Anaplasmataceae, isolated from wild rats and found in Ixodes ovatus ticks. International Journal of Systematic and Evolutionary Microbiology. 54: 1837-43. PMID 15388752 DOI: 10.1099/Ijs.0.63260-0  0.319
2004 Lin Q, Rikihisa Y, Massung RF, Woldehiwet Z, Falco RC. Polymorphism and transcription at the p44-1/p44-18 genomic locus in Anaplasma phagocytophilum strains from diverse geographic regions. Infection and Immunity. 72: 5574-81. PMID 15385454 DOI: 10.1128/Iai.72.10.5574-5581.2004  0.521
2004 Rikihisa Y, Zhang C, Kanter M, Cheng Z, Ohashi N, Fukuda T. Analysis of p51, groESL, and the major antigen P51 in various species of Neorickettsia, an obligatory intracellular bacterium that infects trematodes and mammals. Journal of Clinical Microbiology. 42: 3823-6. PMID 15297539 DOI: 10.1128/Jcm.42.8.3823-3826.2004  0.395
2004 Lin Q, Rikihisa Y, Felek S, Wang X, Massung RF, Woldehiwet Z. Anaplasma phagocytophilum has a functional msp2 gene that is distinct from p44. Infection and Immunity. 72: 3883-9. PMID 15213131 DOI: 10.1128/Iai.72.7.3883-3889.2004  0.68
2004 Zhang C, Rikihisa Y. Proposal to transfer 'Aegyptianella ranarum', an intracellular bacterium of frog red blood cells, to the family Flavobacteriaceae as 'Candidatus Hemobacterium ranarum' comb. nov. Environmental Microbiology. 6: 568-73. PMID 15142244 DOI: 10.1111/J.1462-2920.2004.00559.X  0.359
2004 Wagner ER, Bremer WG, Rikihisa Y, Ewing SA, Needham GR, Unver A, Wang X, Stich RW. Development of a p28-based PCR assay for Ehrlichia chaffeensis. Molecular and Cellular Probes. 18: 111-6. PMID 15051120 DOI: 10.1016/J.Mcp.2003.10.002  0.741
2004 Felek S, Telford S, Falco RC, Rikihisa Y. Sequence analysis of p44 homologs expressed by Anaplasma phagocytophilum in infected ticks feeding on naive hosts and in mice infected by tick attachment. Infection and Immunity. 72: 659-66. PMID 14742506 DOI: 10.1128/Iai.72.2.659-666.2004  0.396
2004 Lin M, Rikihisa Y. Ehrlichia chaffeensis downregulates surface Toll-like receptors 2/4, CD14 and transcription factors PU.1 and inhibits lipopolysaccharide activation of NF-kappa B, ERK 1/2 and p38 MAPK in host monocytes. Cellular Microbiology. 6: 175-86. PMID 14706103 DOI: 10.1046/J.1462-5822.2003.00355.X  0.622
2003 Rikihisa Y, Zhang C, Christensen BM. Molecular characterization of Aegyptianella pullorum (Rickettsiales, Anaplasmataceae). Journal of Clinical Microbiology. 41: 5294-7. PMID 14605188 DOI: 10.1128/Jcm.41.11.5294-5297.2003  0.381
2003 Lin M, Rikihisa Y. Obligatory intracellular parasitism by Ehrlichia chaffeensis and Anaplasma phagocytophilum involves caveolae and glycosylphosphatidylinositol-anchored proteins. Cellular Microbiology. 5: 809-20. PMID 14531896 DOI: 10.1046/J.1462-5822.2003.00322.X  0.651
2003 Felek S, Huang H, Rikihisa Y. Sequence and expression analysis of virB9 of the type IV secretion system of Ehrlichia canis strains in ticks, dogs, and cultured cells. Infection and Immunity. 71: 6063-7. PMID 14500531 DOI: 10.1128/Iai.71.10.6063-6067.2003  0.408
2003 Lin Q, Rikihisa Y, Ohashi N, Zhi N. Mechanisms of variable p44 expression by Anaplasma phagocytophilum. Infection and Immunity. 71: 5650-61. PMID 14500485 DOI: 10.1128/Iai.71.10.5650-5661.2003  0.708
2003 Lin M, Rikihisa Y. Ehrlichia chaffeensis and Anaplasma phagocytophilum lack genes for lipid A biosynthesis and incorporate cholesterol for their survival. Infection and Immunity. 71: 5324-31. PMID 12933880 DOI: 10.1128/Iai.71.9.5324-5331.2003  0.624
2003 Unver A, Rikihisa Y, Kawahara M, Yamamoto S. Analysis of 16S rRNA gene sequences of Ehrlichia canis, Anaplasma platys, and Wolbachia species from canine blood in Japan. Annals of the New York Academy of Sciences. 990: 692-8. PMID 12860708 DOI: 10.1111/J.1749-6632.2003.Tb07445.X  0.665
2003 Rikihisa Y. Mechanisms to create a safe haven by members of the family Anaplasmataceae. Annals of the New York Academy of Sciences. 990: 548-55. PMID 12860688 DOI: 10.1111/J.1749-6632.2003.Tb07425.X  0.349
2003 Okada H, Usuda H, Tajima T, Kawahara M, Yoshino T, Rikihisa Y. Distribution of ehrlichiae in tissues as determined by in-situ hybridization. Journal of Comparative Pathology. 128: 182-7. PMID 12634096 DOI: 10.1053/Jcpa.2002.0624  0.319
2003 Felek S, Greene R, Rikihisa Y. Transcriptional analysis of p30 major outer membrane protein genes of Ehrlichia canis in naturally infected ticks and sequence analysis of p30-10 of E canis from diverse geographic regions. Journal of Clinical Microbiology. 41: 886-8. PMID 12574308 DOI: 10.1128/Jcm.41.2.886-888.2003  0.438
2003 Lin Q, Rikihisa Y, Ohashi N, Zhi N. Mechanisms of Variable p44 Expression by Anaplasma phagocytophilum Infection and Immunity. 71: 7238-7238. DOI: 10.1128/iai.71.12.7238.2003  0.405
2002 Zhi N, Ohashi N, Rikihisa Y. Activation of a p44 pseudogene in Anaplasma phagocytophila by bacterial RNA splicing: a novel mechanism for post-transcriptional regulation of a multigene family encoding immunodominant major outer membrane proteins. Molecular Microbiology. 46: 135-45. PMID 12366837 DOI: 10.1046/J.1365-2958.2002.03143.X  0.672
2002 Kim HY, Mott J, Zhi N, Tajima T, Rikihisa Y. Cytokine gene expression by peripheral blood leukocytes in horses experimentally infected with Anaplasma phagocytophila. Clinical and Diagnostic Laboratory Immunology. 9: 1079-84. PMID 12204963 DOI: 10.1128/Cdli.9.5.1079-1084.2002  0.711
2002 Lin Q, Zhi N, Ohashi N, Horowitz HW, Aguero-Rosenfeld ME, Raffalli J, Wormser GP, Rikihisa Y. Analysis of sequences and loci of p44 homologs expressed by Anaplasma phagocytophila in acutely infected patients. Journal of Clinical Microbiology. 40: 2981-8. PMID 12149362 DOI: 10.1128/Jcm.40.8.2981-2988.2002  0.725
2002 Unver A, Rikihisa Y, Stich RW, Ohashi N, Felek S. The omp-1 major outer membrane multigene family of Ehrlichia chaffeensis is differentially expressed in canine and tick hosts. Infection and Immunity. 70: 4701-4. PMID 12117987 DOI: 10.1128/Iai.70.8.4701-4704.2002  0.701
2002 Kim HY, Rikihisa Y. Roles of p38 mitogen-activated protein kinase, NF-kappaB, and protein kinase C in proinflammatory cytokine mRNA expression by human peripheral blood leukocytes, monocytes, and neutrophils in response to Anaplasma phagocytophila. Infection and Immunity. 70: 4132-41. PMID 12117921 DOI: 10.1128/Iai.70.8.4132-4141.2002  0.542
2002 Liddell AM, Sumner JW, Paddock CD, Rikihisa Y, Unver A, Buller RS, Storch GA. Reinfection with Ehrlichia chaffeensis in a liver transplant recipient. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. 34: 1644-7. PMID 12032902 DOI: 10.1086/340523  0.634
2002 Ohashi N, Zhi N, Lin Q, Rikihisa Y. Characterization and transcriptional analysis of gene clusters for a type IV secretion machinery in human granulocytic and monocytic ehrlichiosis agents. Infection and Immunity. 70: 2128-38. PMID 11895979 DOI: 10.1128/Iai.70.4.2128-2138.2002  0.714
2002 Mott J, Rikihisa Y, Tsunawaki S. Effects of Anaplasma phagocytophila on NADPH oxidase components in human neutrophils and HL-60 cells. Infection and Immunity. 70: 1359-66. PMID 11854221 DOI: 10.1128/Iai.70.3.1359-1366.2002  0.333
2002 Zhi N, Ohashi N, Tajima T, Mott J, Stich RW, Grover D, Telford SR, Lin Q, Rikihisa Y. Transcript heterogeneity of the p44 multigene family in a human granulocytic ehrlichiosis agent transmitted by ticks. Infection and Immunity. 70: 1175-84. PMID 11854198 DOI: 10.1128/Iai.70.3.1175-1184.2002  0.738
2002 Mott J, Muramatsu Y, Seaton E, Martin C, Reed S, Rikihisa Y. Molecular analysis of Neorickettsia risticii in adult aquatic insects in Pennsylvania, in horses infected by ingestion of insects, and isolated in cell culture. Journal of Clinical Microbiology. 40: 690-3. PMID 11825999 DOI: 10.1128/Jcm.40.2.690-693.2002  0.36
2002 Stich RW, Rikihisa Y, Ewing SA, Needham GR, Grover DL, Jittapalapong S. Detection of Ehrlichia canis in canine carrier blood and in individual experimentally infected ticks with a p30-based PCR assay. Journal of Clinical Microbiology. 40: 540-6. PMID 11825969 DOI: 10.1128/Jcm.40.2.540-546.2002  0.43
2002 Lin M, Zhu MX, Rikihisa Y. Rapid activation of protein tyrosine kinase and phospholipase C-gamma2 and increase in cytosolic free calcium are required by Ehrlichia chaffeensis for internalization and growth in THP-1 cells. Infection and Immunity. 70: 889-98. PMID 11796624 DOI: 10.1128/Iai.70.2.889-898.2002  0.61
2002 Zhi N, Ohashi N, Tajima T, Mott J, Stich RW, Grover D, Telford SR, Lin Q, Rikihisa Y. Transcript Heterogeneity of the p44 Multigene Family in a Human Granulocytic Ehrlichiosis Agent Transmitted by Ticks Infection and Immunity. 70: 4754-4754. DOI: 10.1128/iai.70.8.4754.2002-a  0.451
2001 Unver A, Felek S, Paddock CD, Zhi N, Horowitz HW, Wormser GP, Cullman LC, Rikihisa Y. Western blot analysis of sera reactive to human monocytic ehrlichiosis and human granulocytic ehrlichiosis agents. Journal of Clinical Microbiology. 39: 3982-6. PMID 11682518 DOI: 10.1128/Jcm.39.11.3982-3986.2001  0.785
2001 Unver A, Ohashi N, Tajima T, Stich RW, Grover D, Rikihisa Y. Transcriptional analysis of p30 major outer membrane multigene family of Ehrlichia canis in dogs, ticks, and cell culture at different temperatures. Infection and Immunity. 69: 6172-8. PMID 11553557 DOI: 10.1128/Iai.69.10.6172-6178.2001  0.718
2001 Unver A, Perez M, Orellana N, Huang H, Rikihisa Y. Molecular and antigenic comparison of Ehrlichia canis isolates from dogs, ticks, and a human in Venezuela. Journal of Clinical Microbiology. 39: 2788-93. PMID 11473993 DOI: 10.1128/Jcm.39.8.2788-2793.2001  0.711
2001 Neimark H, Johansson KE, Rikihisa Y, Tully JG. Proposal to transfer some members of the genera Haemobartonella and Eperythrozoon to the genus Mycoplasma with descriptions of 'Candidatus Mycoplasma haemofelis', 'Candidatus Mycoplasma haemomuris', 'Candidatus Mycoplasma haemosuis' and 'Candidatus Mycoplasma wenyonii' International Journal of Systematic and Evolutionary Microbiology. 51: 891-899. PMID 11411711 DOI: 10.1099/00207713-51-3-891  0.318
2001 Ohashi N, Rikihisa Y, Unver A. Analysis of transcriptionally active gene clusters of major outer membrane protein multigene family in Ehrlichia canis and E. chaffeensis. Infection and Immunity. 69: 2083-91. PMID 11254561 DOI: 10.1128/Iai.69.4.2083-2091.2001  0.68
2001 Okada H, Tajima T, Kawahara M, Rikihisa Y. Ehrlichial proliferation and acute hepatocellular necrosis in immunocompetent mice experimentally infected with the HF strain of Ehrlichia, closely related to Ehrlichia chaffeensis Journal of Comparative Pathology. 124: 165-171. PMID 11222014 DOI: 10.1053/Jcpa.2000.0447  0.337
2001 Felek S, Unver A, Stich RW, Rikihisa Y. Sensitive detection of Ehrlichia chaffeensis in cell culture, blood, and tick specimens by reverse transcription-PCR. Journal of Clinical Microbiology. 39: 460-3. PMID 11158090 DOI: 10.1128/Jcm.39.2.460-463.2001  0.708
2000 Mott J, Rikihisa Y. Human granulocytic ehrlichiosis agent inhibits superoxide anion generation by human neutrophils Infection and Immunity. 68: 6697-6703. PMID 11083784 DOI: 10.1128/Iai.68.12.6697-6703.2000  0.337
2000 Tajima T, Zhi N, Lin Q, Rikihisa Y, Horowitz HW, Ralfalli J, Wormser GP, Hechemy KE. Comparison of two recombinant major outer membrane proteins of the human granulocytic ehrlichiosis agent for use in an enzyme-linked immunosorbent assay. Clinical and Diagnostic Laboratory Immunology. 7: 652-7. PMID 10882667 DOI: 10.1128/Cdli.7.4.652-657.2000  0.716
2000 Sumner JW, Storch GA, Buller RS, Liddell AM, Stockham SL, Rikihisa Y, Messenger S, Paddock CD. PCR amplification and phylogenetic analysis of groESL operon sequences from Ehrlichia ewingii and Ehrlichia muris Journal of Clinical Microbiology. 38: 2746-2749. PMID 10878077 DOI: 10.1128/Jcm.38.7.2746-2749.2000  0.346
2000 Kim HY, Rikihisa Y. Expression of interleukin-1beta, tumor necrosis factor alpha, and interleukin-6 in human peripheral blood leukocytes exposed to human granulocytic ehrlichiosis agent or recombinant major surface protein P44. Infection and Immunity. 68: 3394-402. PMID 10816490 DOI: 10.1128/Iai.68.6.3394-3402.2000  0.562
2000 Rikihisa Y. Ehrlichial strategy for survival and proliferation in leukocytes Sub-Cellular Biochemistry. 33: 517-538. PMID 10804868 DOI: 10.1007/978-1-4757-4580-1_20  0.357
2000 Yoshiie K, Kim HY, Mott J, Rikihisa Y. Intracellular infection by the human granulocytic ehrlichiosis agent inhibits human neutrophil apoptosis. Infection and Immunity. 68: 1125-33. PMID 10678916 DOI: 10.1128/Iai.68.3.1125-1133.2000  0.579
2000 Kanter M, Mott J, Ohashi N, Fried B, Reed S, Lin YC, Rikihisa Y. Analysis of 16S rRNA and 51-Kilodalton Antigen Gene and Transmission in Mice of Ehrlichia risticii in Virgulate Trematodes from Elimia livescens Snails in Ohio Journal of Clinical Microbiology. 38: 3349-3358. DOI: 10.1128/Jcm.38.9.3349-3358.2000  0.426
2000 Shibata S, Kawahara M, Rikihisa Y, Fujita H, Watanabe Y, Suto C, Ito T. New Ehrlichia Species Closely Related toEhrlichia chaffeensis Isolated from Ixodes ovatusTicks in Japan Journal of Clinical Microbiology. 38: 1331-1338. DOI: 10.1128/Jcm.38.4.1331-1338.2000  0.319
1999 Rikihisa Y. Clinical and biological aspects of infection caused by Ehrlichia chaffeensis Microbes and Infection. 1: 367-376. PMID 10602669 DOI: 10.1016/S1286-4579(99)80053-7  0.393
1999 Unver A, Rikihisa Y, Ohashi N, Cullman LC, Buller R, Storch GA. Western and dot blotting analyses of Ehrlichia chaffeensis indirect fluorescent-antibody assay-positive and -negative human sera by using native and recombinant E. chaffeensis and E. canis antigens. Journal of Clinical Microbiology. 37: 3888-95. PMID 10565902 DOI: 10.1128/Jcm.37.12.3888-3895.1999  0.69
1999 Buller RS, Arens M, Hmiel SP, Paddock CD, Sumner JW, Rikihisa Y, Unver A, Gaudreault-Keener M, Manian FA, Liddell AM, Schmulewitz N, Storch GA. Ehrlichia ewingii, a newly recognized agent of human ehrlichiosis New England Journal of Medicine. 341: 148-155. PMID 10403852 DOI: 10.1056/Nejm199907153410303  0.718
1999 Zhi N, Ohashi N, Rikihisa Y. Multiple p44 genes encoding major outer membrane proteins are expressed in the human granulocytic ehrlichiosis agent. The Journal of Biological Chemistry. 274: 17828-36. PMID 10364227 DOI: 10.1074/Jbc.274.25.17828  0.684
1999 Barnewall RE, Ohashi N, Rikihisa Y. Ehrlichia chaffeensis and E. sennetsu, but Not the human granulocytic ehrlichiosis agent, colocalize with transferrin receptor and up-regulate transferrin receptor mRNA by activating iron-responsive protein 1 Infection and Immunity. 67: 2258-2265. PMID 10225882 DOI: 10.1128/Iai.67.5.2258-2265.1999  0.402
1999 Mott J, Barnewall RE, Rikihisa Y. Human granulocytic Ehrlichiosis agent and Ehrlichia chaffeensis reside in different cytoplasmic compartments in HL-60 cells Infection and Immunity. 67: 1368-1378. PMID 10024584 DOI: 10.1128/Iai.67.3.1368-1378.1999  0.387
1999 Kawahara M, Ito T, Suto C, Shibata S, Rikihisa Y, Hata K, Hirai K. Comparison of Ehrlichia muris Strains Isolated from Wild Mice and Ticks and Serologic Survey of Humans and Animals with E. muris as Antigen Journal of Clinical Microbiology. 37: 1123-1129. DOI: 10.1128/Jcm.37.4.1123-1129.1999  0.373
1998 Kim HY, Rikihisa Y. Characterization of monoclonal antibodies to the 44-kilodalton major outer membrane protein of the human granulocytic ehrlichiosis agent. Journal of Clinical Microbiology. 36: 3278-84. PMID 9774579 DOI: 10.1128/Jcm.36.11.3278-3284.1998  0.626
1998 Ohashi N, Unver A, Zhi N, Rikihisa Y. Cloning and characterization of multigenes encoding the immunodominant 30-kilodalton major outer membrane proteins of Ehrlichia canis and application of the recombinant protein for serodiagnosis. Journal of Clinical Microbiology. 36: 2671-80. PMID 9705412 DOI: 10.1128/Jcm.36.9.2671-2680.1998  0.793
1998 Barlough JE, Reubel GH, Madigan JE, Vredevoe LK, Miller PE, Rikihisa Y. Detection of Ehrlichia risticii, the agent of potomac horse fever, in freshwater stream snails (Pleuroceridae: Juga spp.) from Northern California Applied and Environmental Microbiology. 64: 2888-2893. PMID 9687446 DOI: 10.1128/Aem.64.8.2888-2893.1998  0.33
1998 Zhang Y, Ohashi N, Rikihisa Y. Cloning of the heat shock protein 70 (HSP70) gene of Ehrlichia sennetsu and differential expression of HSP70 and HSP60 mRNA after temperature upshift Infection and Immunity. 66: 3106-3112. PMID 9632573 DOI: 10.1128/Iai.66.7.3106-3112.1998  0.317
1998 Zhi N, Ohashi N, Rikihisa Y, Horowitz HW, Wormser GP, Hechemy K. Cloning and expression of the 44-kilodalton major outer membrane protein gene of the human granulocytic ehrlichiosis agent and application of the recombinant protein to serodiagnosis. Journal of Clinical Microbiology. 36: 1666-73. PMID 9620397 DOI: 10.1128/Jcm.36.6.1666-1673.1998  0.69
1998 Lee EH, Rikihisa Y. Protein kinase A-mediated inhibition of gamma interferon-induced tyrosine phosphorylation of Janus kinases and latent cytoplasmic transcription factors in human monocytes by Ehrlichia chaffeensis Infection and Immunity. 66: 2514-2520. PMID 9596710 DOI: 10.1128/Iai.66.6.2514-2520.1998  0.391
1998 Ohashi N, Zhi N, Zhang Y, Rikihisa Y. Immunodominant major outer membrane proteins of Ehrlichia chaffeensis are encoded by a polymorphic multigene family. Infection and Immunity. 66: 132-9. PMID 9423849 DOI: 10.1128/Iai.66.1.132-139.1998  0.689
1997 Zhi N, Rikihisa Y, Kim HY, Wormser GP, Horowitz HW. Comparison of major antigenic proteins of six strains of the human granulocytic ehrlichiosis agent by Western immunoblot analysis. Journal of Clinical Microbiology. 35: 2606-11. PMID 9316916 DOI: 10.1128/Jcm.35.10.2606-2611.1997  0.736
1997 Mott J, Rikihisa Y, Zhang Y, Reed SM, Yu CY. Comparison of PCR and culture to the indirect fluorescent-antibody test for diagnosis of Potomac horse fever. Journal of Clinical Microbiology. 35: 2215-9. PMID 9276390 DOI: 10.1128/Jcm.35.9.2215-2219.1997  0.388
1997 Zhang Y, Ohashi N, Lee EH, Tamura A, Rikihisa Y. Ehrlichia sennetsu groE operon and antigenic properties of the GroEL homolog Fems Immunology and Medical Microbiology. 18: 39-46. PMID 9215585 DOI: 10.1111/J.1574-695X.1997.Tb01025.X  0.405
1997 Zhang Y, Rikihisa Y. Tyrosine phosphorylation is required for Ehrlichial internalization and replication in P388D1 cells Infection and Immunity. 65: 2959-2964. PMID 9199472 DOI: 10.1128/Iai.65.7.2959-2964.1997  0.359
1997 Lee EH, Rikihisa Y. Anti-Ehrlichia chaffeensis antibody complexed with E. chaffeensis Induces potent proinflammatory cytokine mRNA expression in human monocytes through sustained reduction of IκB-α and activation of NF-κB Infection and Immunity. 65: 2890-2897. PMID 9199464 DOI: 10.1128/Iai.65.7.2890-2897.1997  0.323
1997 Wen B, Rikihisa Y, Mott JM, Greene R, Kim HY, Zhi N, Couto GC, Unver A, Bartsch R. Comparison of nested PCR with immunofluorescent-antibody assay for detection of Ehrlichia canis infection in dogs treated with doxycycline. Journal of Clinical Microbiology. 35: 1852-5. PMID 9196207 DOI: 10.1128/Jcm.35.7.1852-1855.1997  0.798
1997 Rikihisa Y, Kawahara M, Wen B, Kociba G, Fuerst P, Kawamori F, Suto C, Shibata S, Futohashi M. Western immunoblot analysis of Haemobartonella muris and comparison of 16S rRNA gene sequences of H. muris, H. felis, and Eperythrozoon suis. Journal of Clinical Microbiology. 35: 823-9. PMID 9157135 DOI: 10.1128/Jcm.35.4.823-829.1997  0.336
1997 Barnewall RE, Rikihisa Y, Lee EH. Ehrlichia chaffeensis inclusions are early endosomes which selectively accumulate transferrin receptor Infection and Immunity. 65: 1455-1461. PMID 9119487 DOI: 10.1128/Iai.65.4.1455-1461.1997  0.337
1997 Barlough JE, Rikihisa Y, Madigan JE. Nested polymerase chain reaction for detection of Ehrlichia risticii genomic DNA in infected horses Veterinary Parasitology. 68: 367-373. PMID 9106958 DOI: 10.1016/S0304-4017(96)01083-7  0.347
1997 Rikihisa Y, Zhi N, Wormser GP, Wen B, Horowitz HW, Hechemy KE. Ultrastructural and antigenic characterization of a granulocytic ehrlichiosis agent directly isolated and stably cultivated from a patient in New York state. The Journal of Infectious Diseases. 175: 210-3. PMID 8985223  0.619
1997 Madigan JE, Barlough JE, Rikihisa Y, Wen B, Miller PE, Sampson TJ. Identification of an enzootic diarrhea (“Shasta river crud”) in Northern California as potomac horse fever Journal of Equine Veterinary Science. 17: 270-272. DOI: 10.1016/S0737-0806(97)80046-9  0.315
1996 Kawahara M, Suto C, Shibata S, Futohashi M, Rikihisa Y. Impaired antigen specific responses and enhanced polyclonal stimulation in mice infected with Ehrlichia muris Microbiology and Immunology. 40: 575-581. PMID 8887352 DOI: 10.1111/J.1348-0421.1996.Tb01111.X  0.353
1996 Perez M, Rikihisa Y, Wen B. Ehrlichia canis-like agent isolated from a man in Venezuela: Antigenic and genetic characterization Journal of Clinical Microbiology. 34: 2133-2139. PMID 8862572 DOI: 10.1128/Jcm.34.9.2133-2139.1996  0.42
1996 Wen B, Rikihisa Y, Yamamoto S, Kawabata N, Fuerst PA. Characterization of the SF agent, an Ehrlichia sp. isolated from the fluke Stellantchasmus falcatus, by 16S rRNA base sequence, serological, and morphological analyses. International Journal of Systematic Bacteriology. 46: 149-54. PMID 8573488 DOI: 10.1099/00207713-46-1-149  0.385
1995 Rikihisa Y, Zhang Y, Park J. Role of Ca2+ and calmodulin in ehrlichial infection in macrophages Infection and Immunity. 63: 2310-2316. PMID 7768614 DOI: 10.1128/Iai.63.6.2310-2316.1995  0.303
1995 Wen B, Rikihisa Y, Fuerst PA, Chaichanasiriwithaya W. Diversity of 16S rRNA genes of new Ehrlichia strains isolated from horses with clinical signs of Potomac horse fever. International Journal of Systematic Bacteriology. 45: 315-8. PMID 7537065 DOI: 10.1099/00207713-45-2-315  0.331
1995 Wen B, Rikihisa Y, Mott J, Fuerst PA, Kawahara M, Suto C. Ehrlichia muris sp. nov., identified on the basis of 16S rRNA base sequences and serological, morphological, and biological characteristics. International Journal of Systematic Bacteriology. 45: 250-4. PMID 7537059 DOI: 10.1099/00207713-45-2-250  0.346
1995 Pretzman C, Ralph D, Stothard DR, Fuerst PA, Rikihisa Y. 16S rRNA gene sequence of Neorickettsia helminthoeca and its phylogenetic alignment with members of the genus Ehrlichia. International Journal of Systematic Bacteriology. 45: 207-11. PMID 7537055 DOI: 10.1099/00207713-45-2-207  0.323
1994 Iqbal Z, Rikihisa Y. Application of the polymerase chain reaction for the detection of Ehrlichia canis in tissues of dogs Veterinary Microbiology. 42: 281-287. PMID 9133053 DOI: 10.1016/0378-1135(94)90059-0  0.359
1994 Rikihisa Y, Yamamoto S, Kwak I, Iqbal Z, Kociba G, Mott J, Chichanasiriwithaya W. C-reactive protein and α1-acid glycoprotein levels in dogs infected with Ehrlichia canis Journal of Clinical Microbiology. 32: 912-917. PMID 8027343 DOI: 10.1128/Jcm.32.4.912-917.1994  0.367
1994 Iqbal Z, Chaichanasiriwithaya W, Rikihisa Y. Comparison of PCR with other tests for early diagnosis of canine ehrlichiosis Journal of Clinical Microbiology. 32: 1658-1662. PMID 7929754 DOI: 10.1128/Jcm.32.7.1658-1662.1994  0.376
1994 Iqbal Z, Rikihisa Y. Reisolation of Ehrlichia canis from blood and tissues of dogs after doxycycline treatment Journal of Clinical Microbiology. 32: 1644-1649. PMID 7929751 DOI: 10.1128/Jcm.32.7.1644-1649.1994  0.377
1994 Rikihisa Y, Zhang Y, Park J. Inhibition of infection of macrophages with Ehrlichia risticii by cytochalasins, monodansylcadaverine, and taxol Infection and Immunity. 62: 5126-5132. PMID 7927796 DOI: 10.1128/Iai.62.11.5126-5132.1994  0.368
1994 Rikihisa Y, Ewing SA, Fox JC. Western immunoblot analysis of Ehrlichia chaffeensis, E. canis, or E. ewingii infections in dogs and humans. Journal of Clinical Microbiology. 32: 2107-12. PMID 7814533 DOI: 10.1128/Jcm.32.9.2107-2112.1994  0.396
1994 Chaichanasiriwithaya W, Rikihisa Y, Yamamoto S, Reed S, Crawford TB, Perryman LE, Palmer GH. Antigenic, morphologic, and molecular characterization of new Ehrlichia risticii isolates. Journal of Clinical Microbiology. 32: 3026-3033. DOI: 10.1128/Jcm.32.12.3026-3033.1994  0.372
1993 Kawahara M, Suto C, Rikihisa Y, Yamamoto S, Tsuboi Y. Characterization of ehrlichial organisms isolated from a wild mouse Journal of Clinical Microbiology. 31: 89-96. PMID 8380184 DOI: 10.1128/Jcm.31.1.89-96.1993  0.367
1993 Rikihisa Y, Wada R, Reed SM, Yamamoto S. Development of neutralizing antibody in horses infected with Ehrlichia risticii. Veterinary Microbiology. 36: 139-47. PMID 8236775 DOI: 10.1016/0378-1135(93)90135-T  0.374
1992 Rikihisa Y, Ewing SA, Fox JC, Siregar AG, Pasaribu FH, Malole MB. Analyses of Ehrlichia canis and a canine granulocytic Ehrlichia infection. Journal of Clinical Microbiology. 30: 143-8. PMID 1734046 DOI: 10.1128/Jcm.30.1.143-148.1992  0.423
1992 Messick JB, Rikihisa Y. Suppression of Ia antigen expression on gamma interferon treated macrophages infected with Ehrlichia risticii Veterinary Immunology and Immunopathology. 32: 225-241. PMID 1632064 DOI: 10.1016/0165-2427(92)90048-U  0.377
1992 Rikihisa Y, Johnson GC, Wang YZ, Reed SM, Fertel R, Cooke HJ. Loss of absorptive capacity for sodium and chloride in the colon causes diarrhoea in Potomac horse fever. Research in Veterinary Science. 52: 353-62. PMID 1352409 DOI: 10.1016/0034-5288(92)90037-3  0.359
1991 Dawson JE, Rikihisa Y, Ewing SA, Fishbein DB. Serologic diagnosis of human ehrlichiosis using two Ehrlichia canis isolates. The Journal of Infectious Diseases. 163: 564-7. PMID 1995730 DOI: 10.1093/Infdis/163.3.564  0.385
1991 Rikihisa Y. The tribe Ehrlichieae and ehrlichial diseases Clinical Microbiology Reviews. 4: 286-308. PMID 1889044 DOI: 10.1128/Cmr.4.3.286  0.39
1991 Rikihisa Y. Cross-reacting antigens between Neorickettsia helminthoeca and Ehrlichia species, shown by immunofluorescence and western immunoblotting Journal of Clinical Microbiology. 29: 2024-2029. PMID 1774330 DOI: 10.1128/Jcm.29.9.2024-2029.1991  0.356
1991 Rikihisa Y, Stills H, Zimmerman G. Isolation and continuous culture of Neorickettsia helminthoeca in a macrophage cell line Journal of Clinical Microbiology. 29: 1928-1933. PMID 1774317 DOI: 10.1128/Jcm.29.9.1928-1933.1991  0.347
1989 Rikihisa Y, Jiang BM. Effect of antibiotics on clinical, pathologic and immunologic responses in murine Potomac horse fever: Protective effects of doxycycline Veterinary Microbiology. 19: 253-262. PMID 2497577 DOI: 10.1016/0378-1135(89)90071-0  0.338
1988 Wells MY, Rikihisa Y. Lack of lysosomal fusion with phagosomes containing Ehrlichia risticii in P388D1 cells: Abrogation of inhibition with oxytetracycline Infection and Immunity. 56: 3209-3215. PMID 3182078 DOI: 10.1128/Iai.56.12.3209-3215.1988  0.337
1988 Rikihisa Y, Pretzman CI, Johnson GC, Reed SM, Yamamoto S, Andrews F. Clinical, histopathological, and immunological responses of ponies to Ehrlichia sennetsu and subsequent Ehrlichia risticii challenge Infection and Immunity. 56: 2960-2966. PMID 3169993 DOI: 10.1128/Iai.56.11.2960-2966.1988  0.366
1988 Rikihisa Y, Jiang BM. In vitro susceptibilities of Ehrlichia risticii to eight antibiotics Antimicrobial Agents and Chemotherapy. 32: 986-991. PMID 3142345 DOI: 10.1128/Aac.32.7.986  0.307
1987 Rikihisa Y, Johnson G, Burger CJ. Reduced immune responsiveness and lymphoid depletion in mice infected with Ehrlichia risticii Infection and Immunity. 55: 2215-2222. PMID 3497879 DOI: 10.1128/Iai.55.9.2215-2222.1987  0.368
1987 Pretzman CI, Rikihisa Y, Ralph D, Gordon JC, Bech-Nielsen S. Enzyme-linked immunosorbent assay for Potomac horse fever disease. Journal of Clinical Microbiology. 25: 31-36. DOI: 10.1128/Jcm.25.1.31-36.1987  0.337
1986 Cordes DO, Perry BD, Rikihisa Y, Chickering WR. Enterocolitis Caused by Ehrlichia sp. in the Horse (Potomac Horse Fever) Veterinary Pathology. 23: 471-477. PMID 3750739 DOI: 10.1177/030098588602300418  0.329
1985 Rikihisa Y, Perry BD. Causative ehrlichial organisms in Potomac horse fever Infection and Immunity. 49: 513-517. PMID 4030092 DOI: 10.1128/Iai.49.3.513-517.1985  0.334
1985 Rikihisa Y, Perry BD, Cordes DO. Ultrastructural study of Ehrlichial organisms in the large colons of ponies infected with Potomac horse fever Infection and Immunity. 49: 505-512. PMID 4030091 DOI: 10.1128/Iai.49.3.505-512.1985  0.344
1985 Hammerberg C, Hollingshead M, Rikihisa Y, Debuysscher EV. Porcine lymphoblastoid cell lines of B-cell origin Veterinary Immunology and Immunopathology. 10: 367-380. PMID 3879567 DOI: 10.1016/0165-2427(85)90025-X  0.318
1984 Rikihisa Y. Glycogen autophagosomes in polymorphonuclear leukocytes induced by rickettsiae Anatomical Record. 208: 319-327. PMID 6721227 DOI: 10.1002/Ar.1092080302  0.338
1984 Rikihisa Y, Letonja T, Pratt N, Lin YC. Taenia taeniaeformis: Characterization of larval metabolic products and growth of host gastric cells in vitro Experimental Parasitology. 58: 230-238. PMID 6499997 DOI: 10.1016/0014-4894(84)90039-0  0.306
1984 Rikihisa Y, Lin YC. Taenia taeniaeformis: Increased cell growth and neutral mucus production in the gastric mucosa of the rat with a larval infection Experimental Parasitology. 58: 147-155. PMID 6479286 DOI: 10.1016/0014-4894(84)90030-4  0.304
1984 Letonja T, Rikihisa Y, Hammerberg C. Differential cellular response of resistant and susceptible rodents to the early stages of infection of Taenia taeniaeformis International Journal For Parasitology. 14: 551-558. PMID 6241181 DOI: 10.1016/0020-7519(84)90061-4  0.356
1982 Rikihisa Y, Ito S. Entry of Rickettsia tsutsugamushi into polymorphonuclear leukocytes Infection and Immunity. 38. PMID 6815091 DOI: 10.1128/Iai.38.1.343-350.1982  0.315
1980 Rikihisa Y, Ito S. Localization of electron-dense tracers during entry of Rickettsia tsutsugamushi into polymorphonuclear leukocytes Infection and Immunity. 30: 231-243. PMID 6777300 DOI: 10.1128/Iai.30.1.231-243.1980  0.322
1977 Rikihisa Y, Mizuno D. Binding of markers of either side of plasma membranes to the cytoplasmic side of lysosomes Experimental Cell Research. 110: 103-109. PMID 923655 DOI: 10.1016/0014-4827(77)90275-0  0.308
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