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Josee Dupuis - Publications

Affiliations: 
Boston University, Boston, MA, United States 
Area:
Biostatistics Biology
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235 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Suzuki K, Hatzikotoulas K, Southam L, Taylor HJ, Yin X, Lorenz KM, Mandla R, Huerta-Chagoya A, Melloni GEM, Kanoni S, Rayner NW, Bocher O, Arruda AL, Sonehara K, Namba S, ... ... Dupuis J, et al. Genetic drivers of heterogeneity in type 2 diabetes pathophysiology. Nature. PMID 38374256 DOI: 10.1038/s41586-024-07019-6  0.315
2023 Sarnowski C, Huan T, Ma Y, Joehanes R, Beiser A, DeCarli CS, Heard-Costa NL, Levy D, Lin H, Liu CT, Liu C, Meigs JB, Satizabal CL, Florez JC, Hivert MF, ... Dupuis J, et al. Multi-tissue epigenetic analysis identifies distinct associations underlying insulin resistance and Alzheimer's disease at CPT1A locus. Clinical Epigenetics. 15: 173. PMID 37891690 DOI: 10.1186/s13148-023-01589-4  0.349
2023 Liu X, Sun X, Zhang Y, Jiang W, Lai M, Wiggins KL, Raffield LM, Bielak LF, Zhao W, Pitsillides A, Haessler J, Zheng Y, Blackwell TW, Yao J, Guo X, ... ... Dupuis J, et al. Association Between Whole Blood-Derived Mitochondrial DNA Copy Number, Low-Density Lipoprotein Cholesterol, and Cardiovascular Disease Risk. Journal of the American Heart Association. 12: e029090. PMID 37804200 DOI: 10.1161/JAHA.122.029090  0.39
2023 Jiang MZ, Gaynor SM, Li X, Van Buren E, Stilp A, Buth E, Wang FF, Manansala R, Gogarten SM, Li Z, Polfus LM, Salimi S, Bis JC, Pankratz N, Yanek LR, ... ... Dupuis J, et al. Whole Genome Sequencing Based Analysis of Inflammation Biomarkers in the Trans-Omics for Precision Medicine (TOPMed) Consortium. Biorxiv : the Preprint Server For Biology. PMID 37745480 DOI: 10.1101/2023.09.10.555215  0.354
2023 Huerta-Chagoya A, Schroeder P, Mandla R, Deutsch AJ, Zhu W, Petty L, Yi X, Cole JB, Udler MS, Dornbos P, Porneala B, DiCorpo D, Liu CT, Li JH, Szczerbiński L, ... ... Dupuis J, et al. The power of TOPMed imputation for the discovery of Latino-enriched rare variants associated with type 2 diabetes. Diabetologia. PMID 37148359 DOI: 10.1007/s00125-023-05912-9  0.325
2023 Suzuki K, Hatzikotoulas K, Southam L, Taylor HJ, Yin X, Lorenz KM, Mandla R, Huerta-Chagoya A, Rayner NW, Bocher O, Ana Luiza de SVA, Sonehara K, Namba S, Lee SSK, Preuss MH, ... ... Dupuis J, et al. Multi-ancestry genome-wide study in >2.5 million individuals reveals heterogeneity in mechanistic pathways of type 2 diabetes and complications. Medrxiv : the Preprint Server For Health Sciences. PMID 37034649 DOI: 10.1101/2023.03.31.23287839  0.328
2023 Shrine N, Izquierdo AG, Chen J, Packer R, Hall RJ, Guyatt AL, Batini C, Thompson RJ, Pavuluri C, Malik V, Hobbs BD, Moll M, Kim W, Tal-Singer R, Bakke P, ... ... Dupuis J, et al. Multi-ancestry genome-wide association analyses improve resolution of genes and pathways influencing lung function and chronic obstructive pulmonary disease risk. Nature Genetics. 55: 410-422. PMID 36914875 DOI: 10.1038/s41588-023-01314-0  0.304
2023 Westerman KE, Walker ME, Gaynor SM, Wesse J, DiCorpo D, Ma J, Alonso A, Aslibekyan S, Baldridge AS, Bertoni AG, Biggs ML, Brody JA, Chen YI, Dupuis J, Goodarzi MO, et al. Investigating gene-diet interactions impacting the association between macronutrient intake and glycemic traits. Diabetes. PMID 36791419 DOI: 10.2337/db22-0851  0.351
2023 Peljto AL, Blumhagen RZ, Walts AD, Cardwell J, Powers J, Corte TJ, Dickinson JL, Glaspole I, Moodley YP, Vasakova MK, Bendstrup E, Davidsen JR, Borie R, Crestani B, Dieude P, ... ... Dupuis J, et al. Idiopathic Pulmonary Fibrosis Is Associated with Common Genetic Variants and Limited Rare Variants. American Journal of Respiratory and Critical Care Medicine. PMID 36602845 DOI: 10.1164/rccm.202207-1331OC  0.332
2022 Zhang Y, Meigs JB, Liu CT, Dupuis J, Sarnowski C. Leveraging family history in genetic association analyses of binary traits. Bmc Genomics. 23: 678. PMID 36182916 DOI: 10.1186/s12864-022-08897-8  0.328
2022 DiCorpo D, Gaynor SM, Russell EM, Westerman KE, Raffield LM, Majarian TD, Wu P, Sarnowski C, Highland HM, Jackson A, Hasbani NR, de Vries PS, Brody JA, Hidalgo B, Guo X, ... ... Dupuis J, et al. Whole genome sequence association analysis of fasting glucose and fasting insulin levels in diverse cohorts from the NHLBI TOPMed program. Communications Biology. 5: 756. PMID 35902682 DOI: 10.1038/s42003-022-03702-4  0.344
2022 Mahajan A, Spracklen CN, Zhang W, Ng MCY, Petty LE, Kitajima H, Yu GZ, Rüeger S, Speidel L, Kim YJ, Horikoshi M, Mercader JM, Taliun D, Moon S, Kwak SH, ... ... Dupuis J, et al. Multi-ancestry genetic study of type 2 diabetes highlights the power of diverse populations for discovery and translation. Nature Genetics. PMID 35551307 DOI: 10.1038/s41588-022-01058-3  0.364
2021 Haslam DE, Peloso GM, Guirette M, Imamura F, Bartz TM, Pitsillides AN, Wang CA, Li-Gao R, Westra JM, Pitkänen N, Young KL, Graff M, Wood AC, Braun KVE, Luan J, ... ... Dupuis J, et al. Sugar-sweetened Beverage Consumption May Modify Associations between Genetic Variants in the CHREBP Locus and HDL-C and TG Concentrations. Circulation. Genomic and Precision Medicine. PMID 34270325 DOI: 10.1161/CIRCGEN.120.003288  0.328
2021 Goodrich JK, Singer-Berk M, Son R, Sveden A, Wood J, England E, Cole JB, Weisburd B, Watts N, Caulkins L, Dornbos P, Koesterer R, Zappala Z, Zhang H, Maloney KA, ... ... Dupuis J, et al. Determinants of penetrance and variable expressivity in monogenic metabolic conditions across 77,184 exomes. Nature Communications. 12: 3505. PMID 34108472 DOI: 10.1038/s41467-021-23556-4  0.322
2021 Chen J, Spracklen CN, Marenne G, Varshney A, Corbin LJ, Luan J, Willems SM, Wu Y, Zhang X, Horikoshi M, Boutin TS, Mägi R, Waage J, Li-Gao R, Chan KHK, ... ... Dupuis J, et al. The trans-ancestral genomic architecture of glycemic traits. Nature Genetics. PMID 34059833 DOI: 10.1038/s41588-021-00852-9  0.356
2021 Moll M, Jackson VE, Yu B, Grove ML, London SJ, Gharib SA, Bartz TM, Sitlani CM, Dupuis J, O'Connor GT, Xu H, Cassano PA, Patchen BK, Kim WJ, Park J, et al. A Systematic Analysis of Protein-altering Exonic Variants in Chronic Obstructive Pulmonary Disease. American Journal of Physiology. Lung Cellular and Molecular Physiology. PMID 33909500 DOI: 10.1152/ajplung.00009.2021  0.349
2021 Wu P, Wang B, Lubitz SA, Benjamin EJ, Meigs JB, Dupuis J. Approximate conditional phenotype analysis based on genome wide association summary statistics. Scientific Reports. 11: 2518. PMID 33510268 DOI: 10.1038/s41598-021-82000-1  0.332
2020 Sarnowski C, Huan T, Jain D, Liu C, Yao C, Joehanes R, Levy D, Dupuis J. JEM: A joint test to estimate the effect of multiple genetic variants on DNA methylation. Genetic Epidemiology. PMID 33038041 DOI: 10.1002/gepi.22369  0.47
2020 Lancour D, Dupuis J, Mayeux R, Haines JL, Pericak-Vance MA, Schellenberg GC, Crovella M, Farrer LA, Kasif S. Analysis of brain region-specific co-expression networks reveals clustering of established and novel genes associated with Alzheimer disease. Alzheimer's Research & Therapy. 12: 103. PMID 32878640 DOI: 10.1186/S13195-020-00674-7  0.337
2020 Kim JS, Steffen BT, Podolanczuk AJ, Kawut SM, Noth I, Raghu G, Michos ED, Hoffman EA, Axelsson GT, Gudmundsson G, Gudnason V, Gudmundsson EF, Murphy RA, Dupuis J, Xu H, et al. Associations of Omega-3 Fatty acids with Interstitial Lung Disease and Lung Imaging Abnormalities Among Adults. American Journal of Epidemiology. PMID 32803215 DOI: 10.1093/Aje/Kwaa168  0.32
2020 Chen Y, Peloso GM, Liu CT, DeStefano AL, Dupuis J. Evaluation of population stratification adjustment using genome-wide or exonic variants. Genetic Epidemiology. PMID 32608112 DOI: 10.1002/Gepi.22332  0.428
2020 Wu P, Rybin D, Bielak LF, Feitosa MF, Franceschini N, Li Y, Lu Y, Marten J, Musani SK, Noordam R, Raghavan S, Rose LM, Schwander K, Smith AV, Tajuddin SM, ... ... Dupuis J, et al. Smoking-by-genotype interaction in type 2 diabetes risk and fasting glucose. Plos One. 15: e0230815. PMID 32379818 DOI: 10.1371/Journal.Pone.0230815  0.418
2020 Posner DC, Lin H, Meigs JB, Kolaczyk ED, Dupuis J. Convex combination sequence kernel association test for rare-variant studies. Genetic Epidemiology. PMID 32100372 DOI: 10.1002/Gepi.22287  0.432
2020 Granot-Hershkovitz E, Wu P, Karasik D, Peter I, Peloso GM, Levy D, Vasan RS, Adrienne Cupples L, Liu CT, Meigs JB, Siscovick DS, Dupuis J, Friedlander Y, Hochner H. Searching for parent-of-origin effects on cardiometabolic traits in imprinted genomic regions. European Journal of Human Genetics : Ejhg. PMID 31896779 DOI: 10.1038/S41431-019-0568-1  0.449
2020 Tobias DK, Raghavan S, Bick A, Raffield L, Wu P, Dicorpo DA, Dupuis J, Lange L, Rotter JI, Kooperberg CL, Meigs JB, Manson JE. 2256-PUB: Clonal Hematopoiesis of Indeterminate Potential (CHIP), Glycemic Traits, and Type 2 Diabetes (T2D) Risk Diabetes. 69. DOI: 10.2337/Db20-2256-Pub  0.408
2020 Kwak SH, Mercader JM, Leong A, Porneala B, Wu P, Cole JB, Merino J, Park KS, Cho NH, Dupuis J, Florez JC, Meigs JB. 1655-P: Genetic Risk Factors for Incident Cardiovascular Disease in Type 2 Diabetes Patients Diabetes. 69. DOI: 10.2337/Db20-1655-P  0.349
2019 Raffield LM, Iyengar AK, Wang B, Gaynor SM, Spracklen CN, Zhong X, Kowalski MH, Salimi S, Polfus LM, Benjamin EJ, Bis JC, Bowler R, Cade BE, Choi WJ, Comellas AP, ... ... Dupuis J, et al. Allelic Heterogeneity at the CRP Locus Identified by Whole-Genome Sequencing in Multi-ancestry Cohorts. American Journal of Human Genetics. PMID 31883642 DOI: 10.1016/J.Ajhg.2019.12.002  0.453
2019 Wang B, Lunetta K, Dupuis J, Lubitz SA, Trinquart L, Yao L, Ellinor PT, Benjamin EJ, Lin H. Integrative Omics Approach to Identifying Genes Associated with Atrial Fibrillation. Circulation Research. PMID 31801406 DOI: 10.1161/Circresaha.119.315179  0.419
2019 Lim E, Chen H, Dupuis J, Liu CT. A unified method for rare variant analysis of gene-environment interactions. Statistics in Medicine. PMID 31799744 DOI: 10.1002/Sim.8446  0.422
2019 Sarnowski C, Leong A, Raffield LM, Wu P, de Vries PS, DiCorpo D, Guo X, Xu H, Liu Y, Zheng X, Hu Y, Brody JA, Goodarzi MO, Hidalgo BA, Highland HM, ... ... Dupuis J, et al. Impact of Rare and Common Genetic Variants on Diabetes Diagnosis by Hemoglobin A1c in Multi-Ancestry Cohorts: The Trans-Omics for Precision Medicine Program. American Journal of Human Genetics. PMID 31564435 DOI: 10.1016/J.Ajhg.2019.08.010  0.435
2019 Cardona A, Day FR, Perry JRB, Loh M, Chu AY, Lehne B, Paul DS, Lotta LA, Stewart ID, Kerrison ND, Scott RA, Khaw KT, Forouhi NG, Langenberg C, Liu C, ... ... Dupuis J, et al. Epigenome-Wide Association Study of Incident Type 2 Diabetes in a British Population: EPIC-Norfolk Study. Diabetes. PMID 31506343 DOI: 10.2337/Db18-0290  0.554
2019 Murphy AM, Smith CE, Murphy LM, Follis JL, Tanaka T, Richardson K, Noordam R, Lemaitre RN, Kähönen M, Dupuis J, Voortman T, Marouli E, Mook-Kanamori DO, Raitakari OT, Hong J, et al. Potential Interplay Between Dietary Saturated Fats and Genetic Variants of the NLRP3 Inflammasome, to Modulate Insulin Resistance and Diabetes Risk: insights from a Meta-Analysis of 19,005 Individuals. Molecular Nutrition & Food Research. e1900226. PMID 31432628 DOI: 10.1002/Mnfr.201900226  0.374
2019 Hobbs BD, Putman RK, Araki T, Nishino M, Gudmundsson G, Gudnason V, Eiriksdottir G, Zilhao Nogueira NR, Dupuis J, Xu H, O'Connor GT, Manichaikul A, Nguyen J, Podolanczuk AJ, Madahar P, et al. Overlap of Genetic Risk Between Interstitial Lung Abnormalities and Idiopathic Pulmonary Fibrosis. American Journal of Respiratory and Critical Care Medicine. PMID 31339356 DOI: 10.1164/Rccm.201903-0511Oc  0.479
2019 Liu CT, Merino J, Rybin D, DiCorpo D, Benke KS, Bragg-Gresham JL, Canouil M, Corre T, Grallert H, Isaacs A, Kutalik Z, Lahti J, Marullo L, Marzi C, Rasmussen-Torvik LJ, ... ... Dupuis J, et al. Genome-wide Association Study of Change in Fasting Glucose over time in 13,807 non-diabetic European Ancestry Individuals. Scientific Reports. 9: 9439. PMID 31263163 DOI: 10.1038/S41598-019-45823-7  0.421
2019 Liu J, Carnero-Montoro E, van Dongen J, Lent S, Nedeljkovic I, Ligthart S, Tsai PC, Martin TC, Mandaviya PR, Jansen R, Peters MJ, Duijts L, Jaddoe VWV, Tiemeier H, Felix JF, ... ... Dupuis J, et al. An integrative cross-omics analysis of DNA methylation sites of glucose and insulin homeostasis. Nature Communications. 10: 2581. PMID 31197173 DOI: 10.1038/S41467-019-10487-4  0.357
2019 Flannick J, Mercader JM, Fuchsberger C, Udler MS, Mahajan A, Wessel J, Teslovich TM, Caulkins L, Koesterer R, Barajas-Olmos F, Blackwell TW, Boerwinkle E, Brody JA, Centeno-Cruz F, Chen L, ... ... Dupuis J, et al. Exome sequencing of 20,791 cases of type 2 diabetes and 24,440 controls. Nature. PMID 31118516 DOI: 10.1038/s41586-019-1231-2  0.34
2019 Chung J, Jun GR, Dupuis J, Farrer LA. Comparison of methods for multivariate gene-based association tests for complex diseases using common variants. European Journal of Human Genetics : Ejhg. PMID 30683923 DOI: 10.1038/S41431-018-0327-8  0.434
2019 Naj A, Sha J, Leonenko G, Chen Y, Chouraki V, Leber M, Sims R, Grenier-Boley B, Bis JC, Zhao Y, Kuzma AB, Kunkle BW, Karamujić-Čomić H, Lee SJVD, Bellenguez C, ... ... Dupuis J, et al. O2‐10‐06: Genome‐Wide Meta‐Analysis Of Late‐Onset Alzheimer'S Disease Using Rare Variant Imputation In 64,859 Subjects Identifies Risk Loci With Roles In Innate Immunity And Cardiovascular Traits: The International Genomics Of Alzheimer'S Project (Igap) Alzheimers & Dementia. 15. DOI: 10.1016/J.Jalz.2019.06.4510  0.342
2018 Ligthart S, Vaez A, Võsa U, Stathopoulou MG, de Vries PS, Prins BP, Van der Most PJ, Tanaka T, Naderi E, Rose LM, Wu Y, Karlsson R, Barbalic M, Lin H, Pool R, ... ... Dupuis J, et al. Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders. American Journal of Human Genetics. 103: 691-706. PMID 30388399 DOI: 10.1016/J.Ajhg.2018.09.009  0.426
2018 Hendricks AE, Billups SC, Pike HNC, Farooqi IS, Zeggini E, Santorico SA, Barroso I, Dupuis J. ProxECAT: Proxy External Controls Association Test. A new case-control gene region association test using allele frequencies from public controls. Plos Genetics. 14: e1007591. PMID 30325923 DOI: 10.1371/Journal.Pgen.1007591  0.4
2018 Mahajan A, Taliun D, Thurner M, Robertson NR, Torres JM, Rayner NW, Payne AJ, Steinthorsdottir V, Scott RA, Grarup N, Cook JP, Schmidt EM, Wuttke M, Sarnowski C, Mägi R, ... ... Dupuis J, et al. Fine-mapping type 2 diabetes loci to single-variant resolution using high-density imputation and islet-specific epigenome maps. Nature Genetics. PMID 30297969 DOI: 10.1038/S41588-018-0241-6  0.449
2018 Chen Y, Peloso GM, Dupuis J. Evaluation of a phenotype imputation approach using GAW20 simulated data. Bmc Proceedings. 12: 56. PMID 30275899 DOI: 10.1186/S12919-018-0134-9  0.418
2018 Lent S, Xu H, Wang L, Wang Z, Sarnowski C, Hivert MF, Dupuis J. Comparison of novel and existing methods for detecting differentially methylated regions. Bmc Genetics. 19: 84. PMID 30255775 DOI: 10.1186/S12863-018-0637-4  0.321
2018 Sarnowski C, Lent S, Dupuis J. Investigation of parent-of-origin effects induced by fenofibrate treatment on triglycerides levels. Bmc Genetics. 19: 83. PMID 30255771 DOI: 10.1186/S12863-018-0640-9  0.362
2018 Jackson VE, Latourelle JC, Wain LV, Smith AV, Grove ML, Bartz TM, Obeidat M, Province MA, Gao W, Qaiser B, Porteous DJ, Cassano PA, Ahluwalia TS, Grarup N, Li J, ... ... Dupuis J, et al. Meta-analysis of exome array data identifies six novel genetic loci for lung function. Wellcome Open Research. 3: 4. PMID 30175238 DOI: 10.12688/wellcomeopenres.12583.3  0.309
2018 Bis JC, Jian X, Kunkle BW, Chen Y, Hamilton-Nelson KL, Bush WS, Salerno WJ, Lancour D, Ma Y, Renton AE, Marcora E, Farrell JJ, Zhao Y, Qu L, Ahmad S, ... ... Dupuis J, et al. Whole exome sequencing study identifies novel rare and common Alzheimer's-Associated variants involved in immune response and transcriptional regulation. Molecular Psychiatry. PMID 30108311 DOI: 10.1038/S41380-018-0112-7  0.407
2018 Wyss AB, Sofer T, Lee MK, Terzikhan N, Nguyen JN, Lahousse L, Latourelle JC, Smith AV, Bartz TM, Feitosa MF, Gao W, Ahluwalia TS, Tang W, Oldmeadow C, Duan Q, ... ... Dupuis J, et al. Multiethnic meta-analysis identifies ancestry-specific and cross-ancestry loci for pulmonary function. Nature Communications. 9: 2976. PMID 30061609 DOI: 10.1038/S41467-018-05369-0  0.419
2018 Terzikhan N, Sun F, Verhamme FM, Adams HHH, Loth D, Bracke KR, Stricker BHC, Lahousse L, Dupuis J, Brusselle GG, O'Connor GT. Heritability and genome-wide association study of diffusing capacity of the lung. The European Respiratory Journal. PMID 30049742 DOI: 10.1183/13993003.00647-2018  0.427
2018 Merino J, Dashti HS, Li SX, Sarnowski C, Justice AE, Graff M, Papoutsakis C, Smith CE, Dedoussis GV, Lemaitre RN, Wojczynski MK, Männistö S, Ngwa JS, Kho M, Ahluwalia TS, ... ... Dupuis J, et al. Genome-wide meta-analysis of macronutrient intake of 91,114 European ancestry participants from the cohorts for heart and aging research in genomic epidemiology consortium. Molecular Psychiatry. PMID 29988085 DOI: 10.1038/S41380-018-0079-4  0.449
2018 Naj AC, Lin H, Vardarajan BN, White S, Lancour D, Ma Y, Schmidt M, Sun F, Butkiewicz M, Bush WS, Kunkle BW, Malamon J, Amin N, Choi SH, Hamilton-Nelson KL, ... ... Dupuis J, et al. Quality control and integration of genotypes from two calling pipelines for whole genome sequence data in the Alzheimer's disease sequencing project. Genomics. PMID 29857119 DOI: 10.1016/J.Ygeno.2018.05.004  0.383
2018 Mendelson MM, Johannes R, Liu C, Huan T, Yao C, Miao X, Murabito JM, Dupuis J, Levy D, Benjamin EJ, Lin H. Epigenome-Wide Association Study of Soluble Tumor Necrosis Factor Receptor 2 Levels in the Framingham Heart Study. Frontiers in Pharmacology. 9: 207. PMID 29740313 DOI: 10.3389/Fphar.2018.00207  0.498
2018 Vassy JL, Hivert MF, Porneala B, Dauriz M, Florez JC, Dupuis J, Siscovick DS, Fornage M, Rasmussen-Torvik LJ, Bouchard C, Meigs JB. Erratum. Polygenic Type 2 Diabetes Prediction at the Limit of Common Variant Detection. Diabetes 2014;63:2172-2182. Diabetes. PMID 29669744 DOI: 10.2337/Db18-Er06A  0.311
2018 Mahajan A, Wessel J, Willems SM, Zhao W, Robertson NR, Chu AY, Gan W, Kitajima H, Taliun D, Rayner NW, Guo X, Lu Y, Li M, Jensen RA, Hu Y, ... ... Dupuis J, et al. Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes. Nature Genetics. 50: 559-571. PMID 29632382 DOI: 10.1038/S41588-018-0084-1  0.419
2018 Merino J, Leong A, Liu CT, Porneala B, Walford GA, von Grotthuss M, Wang TJ, Flannick J, Dupuis J, Levy D, Gerszten RE, Florez JC, Meigs JB. Metabolomics insights into early type 2 diabetes pathogenesis and detection in individuals with normal fasting glucose. Diabetologia. PMID 29626220 DOI: 10.1007/S00125-018-4599-X  0.312
2018 Blue EE, Bis JC, Dorschner MO, Tsuang DW, Barral SM, Beecham G, Below JE, Bush WS, Butkiewicz M, Cruchaga C, DeStefano A, Farrer LA, Goate A, Haines J, Jaworski J, ... ... Dupuis J, et al. Genetic Variation in Genes Underlying Diverse Dementias May Explain a Small Proportion of Cases in the Alzheimer's Disease Sequencing Project. Dementia and Geriatric Cognitive Disorders. 45: 1-17. PMID 29486463 DOI: 10.1159/000485503  0.309
2018 Jiang X, O'Reilly PF, Aschard H, Hsu YH, Richards JB, Dupuis J, Ingelsson E, Karasik D, Pilz S, Berry D, Kestenbaum B, Zheng J, Luan J, Sofianopoulou E, Streeten EA, et al. Genome-wide association study in 79,366 European-ancestry individuals informs the genetic architecture of 25-hydroxyvitamin D levels. Nature Communications. 9: 260. PMID 29343764 DOI: 10.1038/S41467-017-02662-2  0.457
2018 SRINIVASAN S, LEONG A, UDLER M, PORNEALA BC, MEIGS JB, RICH SS, DUPUIS J. A Comprehensive Type 1 Diabetes Genetic Risk Score Is Associated with Type 2 Diabetes in the Framingham Heart Study Diabetes. 67: 1715-P. DOI: 10.2337/Db18-1715-P  0.436
2017 Sarnowski C, Satizabal CL, DeCarli C, Pitsillides AN, Cupples LA, Vasan RS, Wilson JG, Bis JC, Fornage M, Beiser AS, DeStefano AL, Dupuis J, Seshadri S. Whole genome sequence analyses of brain imaging measures in the Framingham Study. Neurology. PMID 29282330 DOI: 10.1212/Wnl.0000000000004820  0.327
2017 Jun G, Manning A, Almeida M, Zawistowski M, Wood AR, Teslovich TM, Fuchsberger C, Feng S, Cingolani P, Gaulton KJ, Dyer T, Blackwell TW, Chen H, Chines PS, Choi S, ... ... Dupuis J, et al. Evaluating the contribution of rare variants to type 2 diabetes and related traits using pedigrees. Proceedings of the National Academy of Sciences of the United States of America. PMID 29279374 DOI: 10.1073/Pnas.1705859115  0.481
2017 Jason F, Fuchsberger C, Mahajan A, Teslovich TM, Agarwala V, Gaulton KJ, Caulkins L, Koesterer R, Ma C, Moutsianas L, McCarthy DJ, Rivas MA, Perry JRB, Sim X, Blackwell TW, ... ... Dupuis J, et al. Sequence data and association statistics from 12,940 type 2 diabetes cases and controls. Scientific Data. 4: 170179. PMID 29257133 DOI: 10.1038/Sdata.2017.179  0.435
2017 Weng LC, Choi SH, Klarin D, Smith JG, Loh PR, Chaffin M, Roselli C, Hulme OL, Lunetta KL, Dupuis J, Benjamin EJ, Newton-Cheh C, Kathiresan S, Ellinor PT, Lubitz SA. Heritability of Atrial Fibrillation. Circulation. Cardiovascular Genetics. 10. PMID 29237688 DOI: 10.1161/Circgenetics.117.001838  0.385
2017 McKeown NM, Dashti HS, Ma J, Haslam DE, Kiefte-de Jong JC, Smith CE, Tanaka T, Graff M, Lemaitre RN, Rybin D, Sonestedt E, Frazier-Wood AC, Mook-Kanamori DO, Li Y, Wang CA, ... ... Dupuis J, et al. Sugar-sweetened beverage intake associations with fasting glucose and insulin concentrations are not modified by selected genetic variants in a ChREBP-FGF21 pathway: a meta-analysis. Diabetologia. PMID 29098321 DOI: 10.1007/S00125-017-4475-0  0.337
2017 Strawbridge RJ, Silveira A, Hoed MD, Gustafsson S, Luan J, Rybin D, Dupuis J, Li-Gao R, Kavousi M, Dehghan A, Haljas K, Lahti J, Gådin JR, Bäcklund A, de Faire U, et al. Identification of a novel proinsulin-associated SNP and demonstration that proinsulin is unlikely to be a causal factor in subclinical vascular remodelling using Mendelian randomisation. Atherosclerosis. 266: 196-204. PMID 29040868 DOI: 10.1016/J.Atherosclerosis.2017.09.031  0.446
2017 Wheeler E, Leong A, Liu CT, Hivert MF, Strawbridge RJ, Podmore C, Li M, Yao J, Sim X, Hong J, Chu AY, Zhang W, Wang X, Chen P, Maruthur NM, ... ... Dupuis J, et al. Impact of common genetic determinants of Hemoglobin A1c on type 2 diabetes risk and diagnosis in ancestrally diverse populations: A transethnic genome-wide meta-analysis. Plos Medicine. 14: e1002383. PMID 28898252 DOI: 10.1371/Journal.Pmed.1002383  0.473
2017 Sims R, van der Lee SJ, Naj AC, Bellenguez C, Badarinarayan N, Jakobsdottir J, Kunkle BW, Boland A, Raybould R, Bis JC, Martin ER, Grenier-Boley B, Heilmann-Heimbach S, Chouraki V, Kuzma AB, ... ... Dupuis J, et al. Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease. Nature Genetics. PMID 28714976 DOI: 10.1038/Ng.3916  0.421
2017 Scott RA, Scott LJ, Mägi R, Marullo L, Gaulton KJ, Kaakinen M, Pervjakova N, Pers TH, Johnson AD, Eicher JD, Jackson AU, Ferreira T, Lee Y, Ma C, Steinthorsdottir V, ... ... Dupuis J, et al. An Expanded Genome-Wide Association Study of Type 2 Diabetes in Europeans. Diabetes. PMID 28566273 DOI: 10.2337/Db16-1253  0.506
2017 Manichaikul A, Wang XQ, Sun L, Dupuis J, Borczuk AC, Nguyen JN, Raghu G, Hoffman EA, Onengut-Gumuscu S, Farber EA, Kaufman JD, Rabinowitz D, Stukovsky KDH, Kawut SM, Hunninghake GM, et al. Genome-wide association study of subclinical interstitial lung disease in MESA. Respiratory Research. 18: 97. PMID 28521775 DOI: 10.1186/S12931-017-0581-2  0.363
2017 Sebro R, Peloso GM, Dupuis J, Risch NJ. Structured mating: Patterns and implications. Plos Genetics. 13: e1006655. PMID 28384154 DOI: 10.1371/Journal.Pgen.1006655  0.408
2017 Manning A, Highland HM, Gasser J, Sim X, Tukiainen T, Fontanillas P, Grarup N, Rivas MA, Mahajan A, Locke AE, Cingolani P, Pers TH, Viñuela A, Brown AA, Wu Y, ... ... Dupuis J, et al. A Low-Frequency Inactivating Akt2 Variant Enriched in the Finnish Population is Associated With Fasting Insulin Levels and Type 2 Diabetes Risk. Diabetes. PMID 28341696 DOI: 10.2337/Db16-1329  0.435
2017 Merino J, Leong A, Posner DC, Porneala B, Masana L, Dupuis J, Florez JC. Genetically Driven Hyperglycemia Increases Risk of Coronary Artery Disease Separately From Type 2 Diabetes. Diabetes Care. PMID 28298470 DOI: 10.2337/Dc16-2625  0.326
2017 Hobbs BD, de Jong K, Lamontagne M, Bossé Y, Shrine N, Artigas MS, Wain LV, Hall IP, Jackson VE, Wyss AB, London SJ, North KE, Franceschini N, Strachan DP, Beaty TH, ... ... Dupuis J, et al. Genetic loci associated with chronic obstructive pulmonary disease overlap with loci for lung function and pulmonary fibrosis. Nature Genetics. PMID 28166215 DOI: 10.1038/Ng.3752  0.414
2017 Joehanes R, Zhang X, Huan T, Yao C, Ying SX, Nguyen QT, Demirkale CY, Feolo ML, Sharopova NR, Sturcke A, Schäffer AA, Heard-Costa N, Chen H, Liu PC, Wang R, ... ... Dupuis J, et al. Integrated genome-wide analysis of expression quantitative trait loci aids interpretation of genomic association studies. Genome Biology. 18: 16. PMID 28122634 DOI: 10.1186/S13059-016-1142-6  0.462
2017 Aschard H, Tobin MD, Hancock DB, Skurnik D, Sood A, James A, Vernon Smith A, Manichaikul AW, Campbell A, Prins BP, Hayward C, Loth DW, Porteous DJ, Strachan DP, Zeggini E, ... ... Dupuis J, et al. Evidence for large-scale gene-by-smoking interaction effects on pulmonary function. International Journal of Epidemiology. PMID 28082375 DOI: 10.1093/Ije/Dyw318  0.316
2017 Sarnowski C, Satizabal CL, DeCarli CS, Pitsillides AN, Beiser AS, Destefano AL, Dupuis J, Seshadri S. TOPMED WHOLE GENOME SEQUENCE (WGS) ASSOCIATIONS WITH BRAIN MRI MEASURES IN THE FRAMINGHAM STUDY Alzheimer's & Dementia. 13: P219-P220. DOI: 10.1016/J.Jalz.2017.07.097  0.302
2016 Lu C, O'Connor GT, Dupuis J, Kolaczyk ED. Meta-Analysis for Penalized Regression Methods with Multi-Cohort Genome-Wide Association Studies. Human Heredity. 81: 142-149. PMID 28002817 DOI: 10.1159/000447969  0.392
2016 Wang S, Fisher VA, Chen Y, Dupuis J. Comparison of multiple single-nucleotide variant association tests in a meta-analysis of Genetic Analysis Workshop 19 family and unrelated data. Bmc Proceedings. 10: 187-191. PMID 27980634 DOI: 10.1186/S12919-016-0028-7  0.455
2016 Ligthart S, Marzi C, Aslibekyan S, Mendelson MM, Conneely KN, Tanaka T, Colicino E, Waite LL, Joehanes R, Guan W, Brody JA, Elks C, Marioni R, Jhun MA, Agha G, ... ... Dupuis J, et al. DNA methylation signatures of chronic low-grade inflammation are associated with complex diseases. Genome Biology. 17: 255. PMID 27955697 DOI: 10.1186/S13059-016-1119-5  0.444
2016 Hardin M, Cho MH, Sharma SS, Glass K, Castaldi PJ, McDonald ML, Aschard H, Senter-Sylvia J, Tantisira K, Weiss ST, Hersh CP, Morrow JD, Lomas D, Agusti A, Bakke P, ... ... Dupuis J, et al. Sex-based Genetic Association Study Identifies CELSR1 as a Possible COPD Risk Locus Among Women. American Journal of Respiratory Cell and Molecular Biology. PMID 27854507 DOI: 10.1165/Rcmb.2016-0172Oc  0.375
2016 Wang S, Meigs JB, Dupuis J. Joint association analysis of a binary and a quantitative trait in family samples. European Journal of Human Genetics : Ejhg. PMID 27782109 DOI: 10.1038/Ejhg.2016.134  0.472
2016 Chen BH, Hivert MF, Peters MJ, Pilling LC, Hogan JD, Pham LM, Harries LW, Fox CS, Bandinelli S, Dehghan A, Hernandez DG, Hofman A, Hong J, Joehanes R, Johnson AD, ... ... Dupuis J, et al. Peripheral Blood Transcriptomic Signatures of Fasting Glucose and Insulin Concentrations. Diabetes. PMID 27625022 DOI: 10.2337/Db16-0470  0.431
2016 Walford GA, Gustafsson S, Rybin D, Stančáková A, Chen H, Liu CT, Hong J, Jensen RA, Rice K, Morris AP, Mägi R, Tönjes A, Prokopenko I, Kleber ME, Delgado G, ... ... Dupuis J, et al. Genome-wide association study of the modified Stumvoll Insulin Sensitivity Index identifies BCL2 and FAM19A2 as novel insulin sensitivity loci. Diabetes. PMID 27416945 DOI: 10.2337/Db16-0199  0.551
2016 Fuchsberger C, Flannick J, Teslovich TM, Mahajan A, Agarwala V, Gaulton KJ, Ma C, Fontanillas P, Moutsianas L, McCarthy DJ, Rivas MA, Perry JR, Sim X, Blackwell TW, Robertson NR, ... ... Dupuis J, et al. The genetic architecture of type 2 diabetes. Nature. PMID 27398621 DOI: 10.1038/Nature18642  0.458
2016 Liu CT, Raghavan S, Maruthur N, Kabagambe EK, Hong J, Ng MC, Hivert MF, Lu Y, An P, Bentley AR, Drolet AM, Gaulton KJ, Guo X, Armstrong LL, Irvin MR, ... ... Dupuis J, et al. Trans-ethnic Meta-Analysis and Functional Annotation Illuminates the Genetic Architecture of Fasting Glucose and Insulin. American Journal of Human Genetics. PMID 27321945 DOI: 10.1016/J.Ajhg.2016.05.006  0.586
2016 Scott RA, Freitag DF, Li L, Chu AY, Surendran P, Young R, Grarup N, Stancáková A, Chen Y, Varga TV, Yaghootkar H, Luan J, Zhao JH, Willems SM, Wessel J, ... ... Dupuis J, et al. A genomic approach to therapeutic target validation identifies a glucose-lowering GLP1R variant protective for coronary heart disease. Science Translational Medicine. 8: 341ra76. PMID 27252175 DOI: 10.1126/scitranslmed.aad3744  0.475
2016 Xing C, M McCarthy J, Dupuis J, Adrienne Cupples L, B Meigs J, Lin X, S Allen A. Robust analysis of secondary phenotypes in case-control genetic association studies. Statistics in Medicine. PMID 27241694 DOI: 10.1002/Sim.6976  0.377
2016 Hong J, Lunetta KL, Cupples LA, Dupuis J, Liu CT. Evaluation of a Two-Stage Approach in Trans-Ethnic Meta-Analysis in Genome-Wide Association Studies. Genetic Epidemiology. PMID 27061095 DOI: 10.1002/gepi.21963  0.391
2016 Wang S, Zhao JH, An P, Guo X, Jensen RA, Marten J, Huffman JE, Meidtner K, Boeing H, Campbell A, Rice KM, Scott RA, Yao J, Schulze MB, Wareham NJ, ... ... Dupuis J, et al. General Framework for Meta-Analysis of Haplotype Association Tests. Genetic Epidemiology. 40: 244-252. PMID 27027517 DOI: 10.1002/Gepi.21959  0.465
2016 Horikoshi M, Pasquali L, Wiltshire S, Huyghe JR, Mahajan A, Asimit JL, Ferreira T, Locke AE, Robertson NR, Wang X, Sim X, Fujita H, Hara K, Young R, Zhang W, ... ... Dupuis J, et al. Transancestral fine-mapping of four type 2 diabetes susceptibility loci highlights potential causal regulatory mechanisms. Human Molecular Genetics. PMID 26911676 DOI: 10.1093/Hmg/Ddw048  0.445
2016 Leong A, Porneala B, Dupuis J, Florez JC, Meigs JB. Type 2 Diabetes Genetic Predisposition, Obesity, and All-Cause Mortality Risk in the U.S.: A Multiethnic Analysis. Diabetes Care. PMID 26884474 DOI: 10.2337/Dc15-2080  0.381
2016 Willems SM, Cornes BK, Brody JA, Morrison AC, Lipovich L, Dauriz M, Chen Y, Liu CT, Rybin DV, Gibbs RA, Muzny D, Pankow JS, Psaty BM, Boerwinkle E, Rotter JI, ... ... Dupuis J, et al. Association of the IGF1 gene with fasting insulin levels. European Journal of Human Genetics : Ejhg. PMID 26860063 DOI: 10.1038/Ejhg.2016.4  0.531
2016 Kan M, Auer PL, Wang GT, Bucasas KL, Hooker S, Rodriguez A, Li B, Ellis J, Adrienne Cupples L, Ida Chen YD, Dupuis J, Fox CS, Gross MD, Smith JD, Heard-Costa N, et al. Rare variant associations with waist-to-hip ratio in European-American and African-American women from the NHLBI-Exome Sequencing Project. European Journal of Human Genetics : Ejhg. PMID 26757982 DOI: 10.1038/Ejhg.2015.272  0.467
2016 Jian X, Bis JC, Kunkle BW, Hamilton KL, Beecham GW, Bush WS, Salerno W, Lancour D, Ma Y, Chen Y, DeStefano AL, Dupuis J, Boerwinkle E, Schellenberg GD, Seshadri S, et al. Rare Deleterious And Loss-Of-Function Variants In Oprl1 And Gas2L2 Contribute To The Risk Of Late-Onset Alzheimer’S Disease: Alzheimer’S Disease Sequencing Project Case-Control Study Alzheimers & Dementia. 12: 163. DOI: 10.1016/J.Jalz.2016.06.765  0.303
2016 Chen Y, DeStefano AL, Bis JC, Jian X, Lee SJvd, Choi SH, Ahmad S, Cupples LA, Mosley TH, Fitzpatrick AL, Lopez OL, Ikram MA, Psaty BM, Boerwinkle E, Duijn CMv, ... ... Dupuis J, et al. Identification Of Whole Exome Sequencing Variants Associated With Late-Onset Alzheimer'S Disease In The Cohorts For Heart And Aging Research In Genomic Epidemiology (Charge) Consortium Alzheimers & Dementia. 12. DOI: 10.1016/J.Jalz.2016.06.344  0.345
2015 Sitlani CM, Dupuis J, Rice KM, Sun F, Pitsillides AN, Cupples LA, Psaty BM. Genome-wide gene-environment interactions on quantitative traits using family data. European Journal of Human Genetics : Ejhg. PMID 26626313 DOI: 10.1038/Ejhg.2015.253  0.353
2015 Xing C, Huang J, Hsu YH, DeStefano AL, Heard-Costa NL, Wolf PA, Seshadri S, Kiel DP, Cupples LA, Dupuis J. Evaluation of power of the Illumina HumanOmni5M-4v1 BeadChip to detect risk variants for human complex diseases. European Journal of Human Genetics : Ejhg. PMID 26577045 DOI: 10.1038/Ejhg.2015.244  0.451
2015 Gaulton KJ, Ferreira T, Lee Y, Raimondo A, Mägi R, Reschen ME, Mahajan A, Locke A, William Rayner N, Robertson N, Scott RA, Prokopenko I, Scott LJ, Green T, Sparso T, ... ... Dupuis J, et al. Genetic fine mapping and genomic annotation defines causal mechanisms at type 2 diabetes susceptibility loci. Nature Genetics. PMID 26551672 DOI: 10.1038/Ng.3437  0.569
2015 Hochner H, Allard C, Granot-Hershkovitz E, Chen J, Sitlani CM, Sazdovska S, Lumley T, McKnight B, Rice K, Enquobahrie DA, Meigs JB, Kwok P, Hivert MF, Borecki IB, Gomez F, ... ... Dupuis J, et al. Parent-of-Origin Effects of the APOB Gene on Adiposity in Young Adults. Plos Genetics. 11: e1005573. PMID 26451733 DOI: 10.1371/Journal.Pgen.1005573  0.455
2015 Gharib SA, Loth DW, Soler Artigas M, Birkland TP, Wilk JB, Wain LV, Brody J, Obeidat M, Hancock DB, Tang W, Rawal R, Boezen HM, Imboden M, Huffman JE, Lahousse L, ... ... Dupuis J, et al. Integrative Pathway Genomics of Lung Function and Airflow Obstruction. Human Molecular Genetics. PMID 26395457 DOI: 10.1093/Hmg/Ddv378  0.381
2015 Joshi PK, Esko T, Mattsson H, Eklund N, Gandin I, Nutile T, Jackson AU, Schurmann C, Smith AV, Zhang W, Okada Y, Stančáková A, Faul JD, Zhao W, Bartz TM, ... ... Dupuis J, et al. Directional dominance on stature and cognition in diverse human populations. Nature. 523: 459-62. PMID 26131930 DOI: 10.1038/Nature14618  0.396
2015 Li Y, O'Connor GT, Dupuis J, Kolaczyk E. Modeling gene-covariate interactions in sparse regression with group structure for genome-wide association studies. Statistical Applications in Genetics and Molecular Biology. 14: 265-77. PMID 25938221 DOI: 10.1515/Sagmb-2014-0073  0.419
2015 Dauriz M, Porneala BC, Guo X, Bielak LF, Peyser PA, Durant NH, Carnethon MR, Bonadonna RC, Bonora E, Bowden DW, Florez JC, Fornage M, Hivert MF, Jacobs DR, Kabagambe EK, ... ... Dupuis J, et al. Association of a 62 Variants Type 2 Diabetes Genetic Risk Score With Markers of Subclinical Atherosclerosis: A Transethnic, Multicenter Study. Circulation. Cardiovascular Genetics. 8: 507-15. PMID 25805414 DOI: 10.1161/Circgenetics.114.000740  0.39
2015 Wessel J, Chu AY, Willems SM, Wang S, Yaghootkar H, Brody JA, Dauriz M, Hivert MF, Raghavan S, Lipovich L, Hidalgo B, Fox K, Huffman JE, An P, Lu Y, ... ... Dupuis J, et al. Low-frequency and rare exome chip variants associate with fasting glucose and type 2 diabetes susceptibility. Nature Communications. 6: 5897. PMID 25631608 DOI: 10.1038/Ncomms6897  0.528
2015 Mahajan A, Sim X, Ng HJ, Manning A, Rivas MA, Highland HM, Locke AE, Grarup N, Im HK, Cingolani P, Flannick J, Fontanillas P, Fuchsberger C, Gaulton KJ, Teslovich TM, ... ... Dupuis J, et al. Identification and functional characterization of G6PC2 coding variants influencing glycemic traits define an effector transcript at the G6PC2-ABCB11 locus. Plos Genetics. 11: e1004876. PMID 25625282 DOI: 10.1371/Journal.Pgen.1004876  0.476
2015 Raghavan S, Porneala B, McKeown N, Fox CS, Dupuis J, Meigs JB. Metabolic factors and genetic risk mediate familial type 2 diabetes risk in the Framingham Heart Study. Diabetologia. 58: 988-96. PMID 25619168 DOI: 10.1007/S00125-015-3498-7  0.321
2015 Liu C, Dupuis J, Larson MG, Cupples LA, Ordovas JM, Vasan RS, Meigs JB, Jacques PF, Levy D. Revisiting heritability accounting for shared environmental effects and maternal inheritance. Human Genetics. 134: 169-79. PMID 25381465 DOI: 10.1007/S00439-014-1505-6  0.467
2015 Schick UM, Auer PL, Bis JC, Lin H, Wei P, Pankratz N, Lange LA, Brody J, Stitziel NO, Kim DS, Carlson CS, Fornage M, Haessler J, Hsu L, Jackson RD, ... ... Dupuis J, et al. Association of exome sequences with plasma C-reactive protein levels in >9000 participants. Human Molecular Genetics. 24: 559-71. PMID 25187575 DOI: 10.1093/Hmg/Ddu450  0.467
2014 Chen H, Choi SH, Hong J, Lu C, Milton JN, Allard C, Lacey SM, Lin H, Dupuis J. Rare genetic variant analysis on blood pressure in related samples. Bmc Proceedings. 8: S35. PMID 25519320 DOI: 10.1186/1753-6561-8-S1-S35  0.439
2014 Lin H, Joehanes R, Pilling LC, Dupuis J, Lunetta KL, Ying SX, Benjamin EJ, Hernandez D, Singleton A, Melzer D, Munson PJ, Levy D, Ferrucci L, Murabito JM. Whole blood gene expression and interleukin-6 levels. Genomics. 104: 490-5. PMID 25311648 DOI: 10.1016/J.Ygeno.2014.10.003  0.307
2014 Xing C, Dupuis J, Cupples LA. Performance of statistical methods on CHARGE targeted sequencing data. Bmc Genetics. 15: 104. PMID 25277365 DOI: 10.1186/S12863-014-0104-9  0.381
2014 Waterworth DM, Li L, Scott R, Warren L, Gillson C, Aponte J, Sarov-Blat L, Sprecher D, Dupuis J, Reiner A, Psaty BM, Tracy RP, Lin H, McPherson R, Chissoe S, et al. A low-frequency variant in MAPK14 provides mechanistic evidence of a link with myeloperoxidase: a prognostic cardiovascular risk marker. Journal of the American Heart Association. 3. PMID 25164947 DOI: 10.1161/Jaha.114.001074  0.365
2014 Kwan JS, Hsu YH, Cheung CL, Dupuis J, Saint-Pierre A, Eriksson J, Handelman SK, Aragaki A, Karasik D, Pramstaller PP, Kooperberg C, Lacroix AZ, Larson MG, Lau KS, Lorentzon M, et al. Meta-analysis of genome-wide association studies identifies two loci associated with circulating osteoprotegerin levels. Human Molecular Genetics. 23: 6684-93. PMID 25080503 DOI: 10.1093/Hmg/Ddu386  0.435
2014 Chen H, Meigs JB, Dupuis J. Incorporating gene-environment interaction in testing for association with rare genetic variants. Human Heredity. 78: 81-90. PMID 25060534 DOI: 10.1159/000363347  0.405
2014 Tang W, Kowgier M, Loth DW, Soler Artigas M, Joubert BR, Hodge E, Gharib SA, Smith AV, Ruczinski I, Gudnason V, Mathias RA, Harris TB, Hansel NN, Launer LJ, Barnes KC, ... ... Dupuis J, et al. Large-scale genome-wide association studies and meta-analyses of longitudinal change in adult lung function. Plos One. 9: e100776. PMID 24983941 DOI: 10.1371/Journal.Pone.0100776  0.43
2014 Kraja AT, Chasman DI, North KE, Reiner AP, Yanek LR, Kilpeläinen TO, Smith JA, Dehghan A, Dupuis J, Johnson AD, Feitosa MF, Tekola-Ayele F, Chu AY, Nolte IM, Dastani Z, et al. Pleiotropic genes for metabolic syndrome and inflammation. Molecular Genetics and Metabolism. 112: 317-38. PMID 24981077 DOI: 10.1016/J.Ymgme.2014.04.007  0.448
2014 Vimaleswaran KS, Cavadino A, Berry DJ, Jorde R, Dieffenbach AK, Lu C, Alves AC, Heerspink HJ, Tikkanen E, Eriksson J, Wong A, Mangino M, Jablonski KA, Nolte IM, ... ... Dupuis J, et al. Association of vitamin D status with arterial blood pressure and hypertension risk: a mendelian randomisation study. The Lancet. Diabetes & Endocrinology. 2: 719-29. PMID 24974252 DOI: 10.1016/S2213-8587(14)70113-5  0.304
2014 Cornes BK, Brody JA, Nikpoor N, Morrison AC, Dang HC, Ahn BS, Wang S, Dauriz M, Barzilay JI, Dupuis J, Florez JC, Coresh J, Gibbs RA, Kao WH, Liu CT, et al. Association of levels of fasting glucose and insulin with rare variants at the chromosome 11p11.2-MADD locus: Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium Targeted Sequencing Study. Circulation. Cardiovascular Genetics. 7: 374-82. PMID 24951664 DOI: 10.1161/Circgenetics.113.000169  0.52
2014 London SJ, Gao W, Gharib SA, Hancock DB, Wilk JB, House JS, Gibbs RA, Muzny DM, Lumley T, Franceschini N, North KE, Psaty BM, Kovar CL, Coresh J, Zhou Y, ... ... Dupuis J, et al. ADAM19 and HTR4 variants and pulmonary function: Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium Targeted Sequencing Study. Circulation. Cardiovascular Genetics. 7: 350-8. PMID 24951661 DOI: 10.1161/Circgenetics.113.000066  0.406
2014 Lin H, Wang M, Brody JA, Bis JC, Dupuis J, Lumley T, McKnight B, Rice KM, Sitlani CM, Reid JG, Bressler J, Liu X, Davis BC, Johnson AD, O'Donnell CJ, et al. Strategies to design and analyze targeted sequencing data: cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium Targeted Sequencing Study. Circulation. Cardiovascular Genetics. 7: 335-43. PMID 24951659 DOI: 10.1161/Circgenetics.113.000350  0.541
2014 Loth DW, Artigas MS, Gharib SA, Wain LV, Franceschini N, Koch B, Pottinger TD, Smith AV, Duan Q, Oldmeadow C, Lee MK, Strachan DP, James AL, Huffman JE, Vitart V, ... ... Dupuis J, et al. Genome-wide association analysis identifies six new loci associated with forced vital capacity. Nature Genetics. 46: 669-77. PMID 24929828 DOI: 10.1038/Ng.3011  0.393
2014 Ellis J, Lange EM, Li J, Dupuis J, Baumert J, Walston JD, Keating BJ, Durda P, Fox ER, Palmer CD, Meng YA, Young T, Farlow DN, Schnabel RB, Marzi CS, et al. Large multiethnic Candidate Gene Study for C-reactive protein levels: identification of a novel association at CD36 in African Americans. Human Genetics. 133: 985-95. PMID 24643644 DOI: 10.1007/S00439-014-1439-Z  0.428
2014 Vassy JL, Hivert MF, Porneala B, Dauriz M, Florez JC, Dupuis J, Siscovick DS, Fornage M, Rasmussen-Torvik LJ, Bouchard C, Meigs JB. Polygenic type 2 diabetes prediction at the limit of common variant detection. Diabetes. 63: 2172-82. PMID 24520119 DOI: 10.2337/Db13-1663  0.386
2014 Mahajan A, Go MJ, Zhang W, Below JE, Gaulton KJ, Ferreira T, Horikoshi M, Johnson AD, Ng MC, Prokopenko I, ... ... Dupuis J, et al. Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility. Nature Genetics. 46: 234-44. PMID 24509480 DOI: 10.1038/Ng.2897  0.6
2014 Chen H, Lumley T, Brody J, Heard-Costa NL, Fox CS, Cupples LA, Dupuis J. Sequence kernel association test for survival traits. Genetic Epidemiology. 38: 191-7. PMID 24464521 DOI: 10.1002/Gepi.21791  0.376
2014 Manichaikul A, Hoffman EA, Smolonska J, Gao W, Cho MH, Baumhauer H, Budoff M, Austin JH, Washko GR, Carr JJ, Kaufman JD, Pottinger T, Powell CA, Wijmenga C, Zanen P, ... ... Dupuis J, et al. Genome-wide study of percent emphysema on computed tomography in the general population. The Multi-Ethnic Study of Atherosclerosis Lung/SNP Health Association Resource Study. American Journal of Respiratory and Critical Care Medicine. 189: 408-18. PMID 24383474 DOI: 10.1164/Rccm.201306-1061Oc  0.434
2014 Dimas AS, Lagou V, Barker A, Knowles JW, Mägi R, Hivert MF, Benazzo A, Rybin D, Jackson AU, Stringham HM, Song C, Fischer-Rosinsky A, Boesgaard TW, Grarup N, Abbasi FA, ... ... Dupuis J, et al. Impact of type 2 diabetes susceptibility variants on quantitative glycemic traits reveals mechanistic heterogeneity. Diabetes. 63: 2158-71. PMID 24296717 DOI: 10.2337/Db13-0949  0.39
2014 Hendricks AE, Dupuis J, Logue MW, Myers RH, Lunetta KL. Correction for multiple testing in a gene region. European Journal of Human Genetics : Ejhg. 22: 414-8. PMID 23838599 DOI: 10.1038/Ejhg.2013.144  0.377
2013 Yaghootkar H, Lamina C, Scott RA, Dastani Z, Hivert MF, Warren LL, Stancáková A, Buxbaum SG, Lyytikäinen LP, Henneman P, Wu Y, Cheung CY, Pankow JS, Jackson AU, Gustafsson S, ... ... Dupuis J, et al. Mendelian randomization studies do not support a causal role for reduced circulating adiponectin levels in insulin resistance and type 2 diabetes. Diabetes. 62: 3589-98. PMID 23835345 DOI: 10.2337/Db13-0128  0.513
2013 Hunninghake GM, Hatabu H, Okajima Y, Gao W, Dupuis J, Latourelle JC, Nishino M, Araki T, Zazueta OE, Kurugol S, Ross JC, San José Estépar R, Murphy E, Steele MP, Loyd JE, et al. MUC5B promoter polymorphism and interstitial lung abnormalities. The New England Journal of Medicine. 368: 2192-200. PMID 23692170 DOI: 10.1097/01.Sa.0000435633.11233.8A  0.367
2013 Lim S, Hong J, Liu CT, Hivert MF, White CC, Murabito JM, O'Donnell CJ, Dupuis J, Florez JC, Meigs JB. Common variants in and near IRS1 and subclinical cardiovascular disease in the Framingham Heart Study. Atherosclerosis. 229: 149-54. PMID 23659870 DOI: 10.1016/J.Atherosclerosis.2013.03.037  0.566
2013 Reiner AP, Hartiala J, Zeller T, Bis JC, Dupuis J, Fornage M, Baumert J, Kleber ME, Wild PS, Baldus S, Bielinski SJ, Fontes JD, Illig T, Keating BJ, Lange LA, et al. Genome-wide and gene-centric analyses of circulating myeloperoxidase levels in the charge and care consortia. Human Molecular Genetics. 22: 3381-93. PMID 23620142 DOI: 10.1093/Hmg/Ddt189  0.456
2013 Lu C, Latourelle J, O'Connor GT, Dupuis J, Kolaczyk ED. Network-guided sparse regression modeling for detection of gene-by-gene interactions. Bioinformatics (Oxford, England). 29: 1241-9. PMID 23599501 DOI: 10.1093/Bioinformatics/Btt139  0.347
2013 de Miguel-Yanes JM, Porneala B, Pencina MJ, Fox CS, Florez JC, Siscovick DS, Dupuis J, Meigs JB. Lack of interaction of beta-cell-function-associated variants with hypertension on change in fasting glucose and diabetes risk: the Framingham Offspring Study. Journal of Hypertension. 31: 1001-9. PMID 23425704 DOI: 10.1097/Hjh.0B013E32835F5A83  0.422
2013 Liu C, Dupuis J, Larson MG, Levy D. Association testing of the mitochondrial genome using pedigree data. Genetic Epidemiology. 37: 239-47. PMID 23319385 DOI: 10.1002/Gepi.21706  0.492
2013 Chen H, Meigs JB, Dupuis J. Sequence kernel association test for quantitative traits in family samples. Genetic Epidemiology. 37: 196-204. PMID 23280576 DOI: 10.1002/Gepi.21703  0.417
2013 Nettleton JA, Hivert MF, Lemaitre RN, McKeown NM, Mozaffarian D, Tanaka T, Wojczynski MK, Hruby A, Djoussé L, Ngwa JS, Follis JL, Dimitriou M, Ganna A, Houston DK, Kanoni S, ... ... Dupuis J, et al. Meta-analysis investigating associations between healthy diet and fasting glucose and insulin levels and modification by loci associated with glucose homeostasis in data from 15 cohorts. American Journal of Epidemiology. 177: 103-15. PMID 23255780 DOI: 10.1093/Aje/Kws297  0.436
2013 Ng MC, Saxena R, Li J, Palmer ND, Dimitrov L, Xu J, Rasmussen-Torvik LJ, Zmuda JM, Siscovick DS, Patel SR, Crook ED, Sims M, Chen YD, Bertoni AG, Li M, ... ... Dupuis J, et al. Transferability and fine mapping of type 2 diabetes loci in African Americans: the Candidate Gene Association Resource Plus Study. Diabetes. 62: 965-76. PMID 23193183 DOI: 10.2337/Db12-0266  0.498
2013 Hansel NN, Ruczinski I, Rafaels N, Sin DD, Daley D, Malinina A, Huang L, Sandford A, Murray T, Kim Y, Vergara C, Heckbert SR, Psaty BM, Li G, Elliott WM, ... ... Dupuis J, et al. Genome-wide study identifies two loci associated with lung function decline in mild to moderate COPD. Human Genetics. 132: 79-90. PMID 22986903 DOI: 10.1007/S00439-012-1219-6  0.433
2012 Hancock DB, Artigas MS, Gharib SA, Henry A, Manichaikul A, Ramasamy A, Loth DW, Imboden M, Koch B, McArdle WL, Smith AV, Smolonska J, Sood A, Tang W, Wilk JB, ... ... Dupuis J, et al. Genome-wide joint meta-analysis of SNP and SNP-by-smoking interaction identifies novel loci for pulmonary function. Plos Genetics. 8: e1003098. PMID 23284291 DOI: 10.1371/Journal.Pgen.1003098  0.414
2012 Mercader JM, Puiggros M, Segrè AV, Planet E, Sorianello E, Sebastian D, Rodriguez-Cuenca S, Ribas V, Bonàs-Guarch S, Draghici S, Yang C, Mora S, Vidal-Puig A, Dupuis J, et al. Identification of novel type 2 diabetes candidate genes involved in the crosstalk between the mitochondrial and the insulin signaling systems. Plos Genetics. 8: e1003046. PMID 23236286 DOI: 10.1371/Journal.Pgen.1003046  0.434
2012 Chu AY, Guilianini F, Grallert H, Dupuis J, Ballantyne CM, Barratt BJ, Nyberg F, Chasman DI, Ridker PM. Genome-wide association study evaluating lipoprotein-associated phospholipase A2 mass and activity at baseline and after rosuvastatin therapy. Circulation. Cardiovascular Genetics. 5: 676-85. PMID 23118302 DOI: 10.1161/Circgenetics.112.963314  0.364
2012 Liu CT, Ng MC, Rybin D, Adeyemo A, Bielinski SJ, Boerwinkle E, Borecki I, Cade B, Chen YD, Djousse L, Fornage M, Goodarzi MO, Grant SF, Guo X, Harris T, ... ... Dupuis J, et al. Transferability and fine-mapping of glucose and insulin quantitative trait loci across populations: CARe, the Candidate Gene Association Resource. Diabetologia. 55: 2970-84. PMID 22893027 DOI: 10.1007/S00125-012-2656-4  0.576
2012 Scott RA, Lagou V, Welch RP, Wheeler E, Montasser ME, Luan J, Mägi R, Strawbridge RJ, Rehnberg E, Gustafsson S, Kanoni S, Rasmussen-Torvik LJ, Yengo L, Lecoeur C, Shungin D, ... ... Dupuis J, et al. Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways. Nature Genetics. 44: 991-1005. PMID 22885924 DOI: 10.1038/Ng.2385  0.6
2012 Morris AP, Voight BF, Teslovich TM, Ferreira T, Segrè AV, Steinthorsdottir V, Strawbridge RJ, Khan H, Grallert H, Mahajan A, Prokopenko I, Kang HM, Dina C, Esko T, Fraser RM, ... ... Dupuis J, et al. Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes. Nature Genetics. 44: 981-90. PMID 22885922 DOI: 10.1038/Ng.2383  0.565
2012 Wilk JB, Shrine NR, Loehr LR, Zhao JH, Manichaikul A, Lopez LM, Smith AV, Heckbert SR, Smolonska J, Tang W, Loth DW, Curjuric I, Hui J, Cho MH, Latourelle JC, ... ... Dupuis J, et al. Genome-wide association studies identify CHRNA5/3 and HTR4 in the development of airflow obstruction. American Journal of Respiratory and Critical Care Medicine. 186: 622-32. PMID 22837378 DOI: 10.1164/Rccm.201202-0366Oc  0.44
2012 Billings LK, Hsu YH, Ackerman RJ, Dupuis J, Voight BF, Rasmussen-Torvik LJ, Hercberg S, Lathrop M, Barnes D, Langenberg C, Hui J, Fu M, Bouatia-Naji N, Lecoeur C, An P, et al. Impact of common variation in bone-related genes on type 2 diabetes and related traits. Diabetes. 61: 2176-86. PMID 22698912 DOI: 10.2337/Db11-1515  0.485
2012 Perry JR, Voight BF, Yengo L, Amin N, Dupuis J, Ganser M, Grallert H, Navarro P, Li M, Qi L, Steinthorsdottir V, Scott RA, Almgren P, Arking DE, Aulchenko Y, et al. Stratifying type 2 diabetes cases by BMI identifies genetic risk variants in LAMA1 and enrichment for risk variants in lean compared to obese cases. Plos Genetics. 8: e1002741. PMID 22693455 DOI: 10.1371/Journal.Pgen.1002741  0.369
2012 Manning AK, Hivert MF, Scott RA, Grimsby JL, Bouatia-Naji N, Chen H, Rybin D, Liu CT, Bielak LF, Prokopenko I, Amin N, Barnes D, Cadby G, Hottenga JJ, Ingelsson E, ... ... Dupuis J, et al. A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance. Nature Genetics. 44: 659-69. PMID 22581228 DOI: 10.1038/Ng.2274  0.479
2012 Grimsby JL, Porneala BC, Vassy JL, Yang Q, Florez JC, Dupuis J, Liu T, Yesupriya A, Chang MH, Ned RM, Dowling NF, Khoury MJ, Meigs JB. Race-ethnic differences in the association of genetic loci with HbA1c levels and mortality in U.S. adults: the third National Health and Nutrition Examination Survey (NHANES III). Bmc Medical Genetics. 13: 30. PMID 22540250 DOI: 10.1186/1471-2350-13-30  0.449
2012 Dastani Z, Hivert MF, Timpson N, Perry JR, Yuan X, Scott RA, Henneman P, Heid IM, Kizer JR, Lyytikäinen LP, Fuchsberger C, Tanaka T, Morris AP, Small K, Isaacs A, ... ... Dupuis J, et al. Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals. Plos Genetics. 8: e1002607. PMID 22479202 DOI: 10.1371/Journal.Pgen.1002607  0.545
2012 Scott RA, Chu AY, Grarup N, Manning AK, Hivert MF, Shungin D, Tönjes A, Yesupriya A, Barnes D, Bouatia-Naji N, Glazer NL, Jackson AU, Kutalik Z, Lagou V, Marek D, ... ... Dupuis J, et al. No interactions between previously associated 2-hour glucose gene variants and physical activity or BMI on 2-hour glucose levels. Diabetes. 61: 1291-6. PMID 22415877 DOI: 10.2337/Db11-0973  0.416
2012 Palmer ND, McDonough CW, Hicks PJ, Roh BH, Wing MR, An SS, Hester JM, Cooke JN, Bostrom MA, Rudock ME, Talbert ME, Lewis JP, Ferrara A, ... ... Dupuis J, et al. A genome-wide association search for type 2 diabetes genes in African Americans. Plos One. 7: e29202. PMID 22238593 DOI: 10.1371/Journal.Pone.0029202  0.483
2012 Grallert H, Dupuis J, Bis JC, Dehghan A, Barbalic M, Baumert J, Lu C, Smith NL, Uitterlinden AG, Roberts R, Khuseyinova N, Schnabel RB, Rice KM, Rivadeneira F, Hoogeveen RC, et al. Eight genetic loci associated with variation in lipoprotein-associated phospholipase A2 mass and activity and coronary heart disease: meta-analysis of genome-wide association studies from five community-based studies. European Heart Journal. 33: 238-51. PMID 22003152 DOI: 10.1093/Eurheartj/Ehr372  0.39
2011 Choi SH, Liu C, Dupuis J, Logue MW, Jun G. Using linkage analysis of large pedigrees to guide association analyses. Bmc Proceedings. 5: S79. PMID 22373287 DOI: 10.1186/1753-6561-5-S9-S79  0.533
2011 Chen H, Hendricks AE, Cheng Y, Cupples AL, Dupuis J, Liu CT. Comparison of statistical approaches to rare variant analysis for quantitative traits. Bmc Proceedings. 5: S113. PMID 22373209 DOI: 10.1186/1753-6561-5-S9-S113  0.548
2011 Magnani JW, Rienstra M, Lin H, Sinner MF, Lubitz SA, McManus DD, Dupuis J, Ellinor PT, Benjamin EJ. Atrial fibrillation: current knowledge and future directions in epidemiology and genomics. Circulation. 124: 1982-93. PMID 22042927 DOI: 10.1161/Circulationaha.111.039677  0.319
2011 Kiechl S, Paré G, Barbalic M, Qi L, Dupuis J, Dehghan A, Bis JC, Laxton RC, Xiao Q, Bonora E, Willeit J, Xu Q, Witteman JC, Chasman D, Tracy RP, et al. Association of variation at the ABO locus with circulating levels of soluble intercellular adhesion molecule-1, soluble P-selectin, and soluble E-selectin: a meta-analysis. Circulation. Cardiovascular Genetics. 4: 681-6. PMID 22010135 DOI: 10.1161/Circgenetics.111.960682  0.354
2011 Strawbridge RJ, Dupuis J, Prokopenko I, Barker A, Ahlqvist E, Rybin D, Petrie JR, Travers ME, Bouatia-Naji N, Dimas AS, Nica A, Wheeler E, Chen H, Voight BF, Taneera J, et al. Genome-wide association identifies nine common variants associated with fasting proinsulin levels and provides new insights into the pathophysiology of type 2 diabetes. Diabetes. 60: 2624-34. PMID 21873549 DOI: 10.2337/Db11-0415  0.485
2011 Vassy JL, Shrader P, Yang Q, Liu T, Yesupriya A, Chang MH, Dowling NF, Ned RM, Dupuis J, Florez JC, Khoury MJ, Meigs JB. Genetic associations with metabolic syndrome and its quantitative traits by race/ethnicity in the United States. Metabolic Syndrome and Related Disorders. 9: 475-82. PMID 21848424 DOI: 10.1089/Met.2011.0021  0.398
2011 Kanoni S, Nettleton JA, Hivert MF, Ye Z, van Rooij FJ, Shungin D, Sonestedt E, Ngwa JS, Wojczynski MK, Lemaitre RN, Gustafsson S, Anderson JS, Tanaka T, Hindy G, Saylor G, ... ... Dupuis J, et al. Total zinc intake may modify the glucose-raising effect of a zinc transporter (SLC30A8) variant: a 14-cohort meta-analysis. Diabetes. 60: 2407-16. PMID 21810599 DOI: 10.2337/Db11-0176  0.381
2011 de Miguel-Yanes JM, Manning AK, Shrader P, McAteer JB, Goel A, Hamsten A, Fox CS, Florez JC, Dupuis J, Meigs JB. Variants at the endocannabinoid receptor CB1 gene (CNR1) and insulin sensitivity, type 2 diabetes, and coronary heart disease. Obesity (Silver Spring, Md.). 19: 2031-7. PMID 21633404 DOI: 10.1038/Oby.2011.135  0.468
2011 Peloso GM, Dupuis J, Lunetta KL. Evaluation of methods accounting for population structure with pedigree data and continuous outcomes. Genetic Epidemiology. 35: 427-36. PMID 21618600 DOI: 10.1002/Gepi.20590  0.316
2011 Paré G, Ridker PM, Rose L, Barbalic M, Dupuis J, Dehghan A, Bis JC, Benjamin EJ, Shiffman D, Parker AN, Chasman DI. Genome-wide association analysis of soluble ICAM-1 concentration reveals novel associations at the NFKBIK, PNPLA3, RELA, and SH2B3 loci. Plos Genetics. 7: e1001374. PMID 21533024 DOI: 10.1371/Journal.Pgen.1001374  0.488
2011 Dehghan A, Dupuis J, Barbalic M, Bis JC, Eiriksdottir G, Lu C, Pellikka N, Wallaschofski H, Kettunen J, Henneman P, Baumert J, Strachan DP, Fuchsberger C, Vitart V, Wilson JF, et al. Meta-analysis of genome-wide association studies in >80 000 subjects identifies multiple loci for C-reactive protein levels. Circulation. 123: 731-8. PMID 21300955 DOI: 10.1161/Circulationaha.110.948570  0.487
2011 Manning AK, LaValley M, Liu CT, Rice K, An P, Liu Y, Miljkovic I, Rasmussen-Torvik L, Harris TB, Province MA, Borecki IB, Florez JC, Meigs JB, Cupples LA, Dupuis J. Meta-analysis of gene-environment interaction: joint estimation of SNP and SNP × environment regression coefficients. Genetic Epidemiology. 35: 11-8. PMID 21181894 DOI: 10.1002/Gepi.20546  0.573
2011 de Miguel-Yanes JM, Shrader P, Pencina MJ, Fox CS, Manning AK, Grant RW, Dupuis J, Florez JC, D'Agostino RB, Cupples LA, Meigs JB. Genetic risk reclassification for type 2 diabetes by age below or above 50 years using 40 type 2 diabetes risk single nucleotide polymorphisms. Diabetes Care. 34: 121-5. PMID 20889853 DOI: 10.2337/Dc10-1265  0.393
2011 Nettleton JA, McKeown NM, Kanoni S, Lemaitre RN, Hivert MF, Ngwa J, Van Rooij FJA, Sonestedt E, Wojczynski MK, Ye Z, Tanaka T, Garcia M, Anderson JS, Follis JL, Djousse L, ... ... Dupuis J, et al. Interactions of dietary whole-grain intake with fasting glucose- and insulin-related genetic loci in individuals of European descent: A meta-analysis of 14 cohort studies (Diabetes Care (2010) 33 (2684-2691)) Diabetes Care. 34: 785-786. DOI: 10.2337/Dc11-Er03  0.368
2011 Wang TJ, Zhang F, Richards JB, Kestenbaum B, Van Meurs JB, Berry D, Kiel DP, Streeten EA, Ohlsson C, Koller DL, Peltonen L, Cooper JD, O'Reilly PF, Houston DK, Glazer NL, ... ... Dupuis J, et al. Common genetic determinants of vitamin D insufficiency: A genome-wide association study Obstetrical and Gynecological Survey. 66: 91-93. DOI: 10.1097/Ogx.0B013E318216B03D  0.371
2011 Voight BF, Scott LJ, Steinthorsdottir V, Morris AP, Dina C, Welch RP, Zeggini E, Huth C, Aulchenko YS, Thorleifsson G, McCulloch LJ, Ferreira T, Grallert H, Amin N, Wu G, ... ... Dupuis J, et al. Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis (vol 42, pg 579, 2010) Nature Genetics. 43: 388-388. DOI: 10.1038/Ng0411-388B  0.377
2010 Soranzo N, Sanna S, Wheeler E, Gieger C, Radke D, Dupuis J, Bouatia-Naji N, Langenberg C, Prokopenko I, Stolerman E, Sandhu MS, Heeney MM, Devaney JM, Reilly MP, Ricketts SL, et al. Common variants at 10 genomic loci influence hemoglobin A₁(C) levels via glycemic and nonglycemic pathways. Diabetes. 59: 3229-39. PMID 20858683 DOI: 10.2337/Db10-0502  0.446
2010 Yang Q, Liu T, Shrader P, Yesupriya A, Chang MH, Dowling NF, Ned RM, Dupuis J, Florez JC, Khoury MJ, Meigs JB. Racial/ethnic differences in association of fasting glucose-associated genomic loci with fasting glucose, HOMA-B, and impaired fasting glucose in the U.S. adult population. Diabetes Care. 33: 2370-7. PMID 20805255 DOI: 10.2337/Dc10-0898  0.38
2010 Voight BF, Scott LJ, Steinthorsdottir V, Morris AP, Dina C, Welch RP, Zeggini E, Huth C, Aulchenko YS, Thorleifsson G, McCulloch LJ, Ferreira T, Grallert H, Amin N, Wu G, ... ... Dupuis J, et al. Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis. Nature Genetics. 42: 579-89. PMID 20581827 DOI: 10.1038/Ng.609  0.441
2010 Wang TJ, Zhang F, Richards JB, Kestenbaum B, van Meurs JB, Berry D, Kiel DP, Streeten EA, Ohlsson C, Koller DL, Peltonen L, Cooper JD, O'Reilly PF, Houston DK, Glazer NL, ... ... Dupuis J, et al. Common genetic determinants of vitamin D insufficiency: a genome-wide association study. Lancet. 376: 180-8. PMID 20541252 DOI: 10.1016/S0140-6736(10)60588-0  0.324
2010 Qi L, Cornelis MC, Kraft P, Stanya KJ, Linda Kao WH, Pankow JS, Dupuis J, Florez JC, Fox CS, Paré G, Sun Q, Girman CJ, Laurie CC, Mirel DB, Manolio TA, et al. Genetic variants at 2q24 are associated with susceptibility to type 2 diabetes. Human Molecular Genetics. 19: 2706-15. PMID 20418489 DOI: 10.1093/Hmg/Ddq156  0.49
2010 Ingelsson E, Langenberg C, Hivert MF, Prokopenko I, Lyssenko V, Dupuis J, Mägi R, Sharp S, Jackson AU, Assimes TL, Shrader P, Knowles JW, Zethelius B, Abbasi FA, Bergman RN, et al. Detailed physiologic characterization reveals diverse mechanisms for novel genetic Loci regulating glucose and insulin metabolism in humans. Diabetes. 59: 1266-75. PMID 20185807 DOI: 10.2337/Db09-1568  0.353
2010 Barbalic M, Dupuis J, Dehghan A, Bis JC, Hoogeveen RC, Schnabel RB, Nambi V, Bretler M, Smith NL, Peters A, Lu C, Tracy RP, Aleksic N, Heeriga J, Keaney JF, et al. Large-scale genomic studies reveal central role of ABO in sP-selectin and sICAM-1 levels. Human Molecular Genetics. 19: 1863-72. PMID 20167578 DOI: 10.1093/Hmg/Ddq061  0.399
2010 Dupuis J, Langenberg C, Prokopenko I, Saxena R, Soranzo N, Jackson AU, Wheeler E, Glazer NL, Bouatia-Naji N, Gloyn AL, Lindgren CM, Mägi R, Morris AP, Randall J, Johnson T, et al. New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk. Nature Genetics. 42: 105-16. PMID 20081858 DOI: 10.1038/Ng.520  0.427
2010 Saxena R, Hivert MF, Langenberg C, Tanaka T, Pankow JS, Vollenweider P, Lyssenko V, Bouatia-Naji N, Dupuis J, Jackson AU, Kao WH, Li M, Glazer NL, Manning AK, Luan J, et al. Genetic variation in GIPR influences the glucose and insulin responses to an oral glucose challenge. Nature Genetics. 42: 142-8. PMID 20081857 DOI: 10.1038/Ng.521  0.385
2010 Karasik D, Dupuis J, Cho K, Cupples LA, Zhou Y, Kiel DP, Demissie S. Refined QTLs of osteoporosis-related traits by linkage analysis with genome-wide SNPs: Framingham SHARe. Bone. 46: 1114-21. PMID 20064633 DOI: 10.1016/J.Bone.2010.01.001  0.622
2010 Schnabel RB, Baumert J, Barbalic M, Dupuis J, Ellinor PT, Durda P, Dehghan A, Bis JC, Illig T, Morrison AC, Jenny NS, Keaney JF, Gieger C, Tilley C, Yamamoto JF, et al. Duffy antigen receptor for chemokines (Darc) polymorphism regulates circulating concentrations of monocyte chemoattractant protein-1 and other inflammatory mediators. Blood. 115: 5289-99. PMID 20040767 DOI: 10.1182/Blood-2009-05-221382  0.42
2010 Heid IM, Henneman P, Hicks A, Coassin S, Winkler T, Aulchenko YS, Fuchsberger C, Song K, Hivert MF, Waterworth DM, Timpson NJ, Richards JB, Perry JR, Tanaka T, Amin N, ... ... Dupuis J, et al. Clear detection of ADIPOQ locus as the major gene for plasma adiponectin: results of genome-wide association analyses including 4659 European individuals. Atherosclerosis. 208: 412-20. PMID 20018283 DOI: 10.1016/J.Atherosclerosis.2009.11.035  0.35
2010 Chen MH, Van Eerdewegh P, Vincent QB, Alcais A, Abel L, Dupuis J. Evaluation of approaches to identify associated SNPs that explain the linkage evidence in nuclear families with affected siblings. Human Heredity. 69: 104-19. PMID 19996608 DOI: 10.1159/000264448  0.616
2010 Dupuis J, Langenberg C, Prokopenko I, Saxena R, Soranzo N, Jackson AU, Wheeler E, Glazer NL, Bouatia-Naji N, Gloyn AL, Lindgren CM, Mägi R, Morris AP, Randall J, Johnson T, et al. Erratum: New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk Nature Genetics. 42: 464-464. DOI: 10.1038/Ng0510-464A  0.369
2009 Schnabel RB, Lunetta KL, Larson MG, Dupuis J, Lipinska I, Rong J, Chen MH, Zhao Z, Yamamoto JF, Meigs JB, Nicaud V, Perret C, Zeller T, Blankenberg S, Tiret L, et al. The relation of genetic and environmental factors to systemic inflammatory biomarker concentrations. Circulation. Cardiovascular Genetics. 2: 229-37. PMID 20031590 DOI: 10.1161/Circgenetics.108.804245  0.587
2009 Manning AK, Ngwa JS, Hendricks AE, Liu CT, Johnson AD, Dupuis J, Cupples LA. Incorporating biological knowledge in the search for gene x gene interaction in genome-wide association studies. Bmc Proceedings. 3: S81. PMID 20018077 DOI: 10.1186/1753-6561-3-S7-S81  0.512
2009 Hendricks AE, Zhu Y, Dupuis J. Genome-wide association and linkage analysis of quantitative traits: comparison of likelihood-ratio test and conditional score statistic. Bmc Proceedings. 3: S100. PMID 20017964 DOI: 10.1186/1753-6561-3-S7-S100  0.471
2009 Richards JB, Waterworth D, O'Rahilly S, Hivert MF, Loos RJ, Perry JR, Tanaka T, Timpson NJ, Semple RK, Soranzo N, Song K, Rocha N, Grundberg E, Dupuis J, Florez JC, et al. A genome-wide association study reveals variants in ARL15 that influence adiponectin levels. Plos Genetics. 5: e1000768. PMID 20011104 DOI: 10.1371/Journal.Pgen.1000768  0.464
2009 Cho K, Dupuis J. Handling linkage disequilibrium in qualitative trait linkage analysis using dense SNPs: a two-step strategy. Bmc Genetics. 10: 44. PMID 19664279 DOI: 10.1186/1471-2156-10-44  0.558
2009 Heard-Costa NL, Zillikens MC, Monda KL, Johansson A, Harris TB, Fu M, Haritunians T, Feitosa MF, Aspelund T, Eiriksdottir G, Garcia M, Launer LJ, Smith AV, Mitchell BD, McArdle PF, ... ... Dupuis J, et al. NRXN3 is a novel locus for waist circumference: a genome-wide association study from the CHARGE Consortium. Plos Genetics. 5: e1000539. PMID 19557197 DOI: 10.1371/Journal.Pgen.1000539  0.435
2009 Dupuis J, Shi J, Manning AK, Benjamin EJ, Meigs JB, Cupples LA, Siegmund D. Mapping quantitative traits in unselected families: algorithms and examples. Genetic Epidemiology. 33: 617-27. PMID 19278016 DOI: 10.1002/Gepi.20413  0.379
2009 Stolerman ES, Manning AK, McAteer JB, Fox CS, Dupuis J, Meigs JB, Florez JC. TCF7L2 variants are associated with increased proinsulin/insulin ratios but not obesity traits in the Framingham Heart Study. Diabetologia. 52: 614-20. PMID 19183934 DOI: 10.1007/S00125-009-1266-2  0.401
2009 Lieb W, Manning AK, Florez JC, Dupuis J, Cupples LA, McAteer JB, Vasan RS, Hoffmann U, O'Donnell CJ, Meigs JB, Fox CS. Variants in the CNR1 and the FAAH genes and adiposity traits in the community. Obesity (Silver Spring, Md.). 17: 755-60. PMID 19165169 DOI: 10.1038/Oby.2008.608  0.419
2009 Kääb S, Darbar D, van Noord C, Dupuis J, Pfeufer A, Newton-Cheh C, Schnabel R, Makino S, Sinner MF, Kannankeril PJ, Beckmann BM, Choudry S, Donahue BS, Heeringa J, Perz S, et al. Large scale replication and meta-analysis of variants on chromosome 4q25 associated with atrial fibrillation. European Heart Journal. 30: 813-9. PMID 19141561 DOI: 10.1093/Eurheartj/Ehn578  0.352
2009 Schnabel R, Dupuis J, Larson MG, Lunetta KL, Robins SJ, Zhu Y, Rong J, Yin X, Stirnadel HA, Nelson JJ, Wilson PW, Keaney JF, Vasan RS, Benjamin EJ. Clinical and genetic factors associated with lipoprotein-associated phospholipase A2 in the Framingham Heart Study. Atherosclerosis. 204: 601-7. PMID 19135199 DOI: 10.1016/J.Atherosclerosis.2008.10.030  0.366
2009 Hivert MF, Manning AK, McAteer JB, Dupuis J, Fox CS, Cupples LA, Meigs JB, Florez JC. Association of variants in RETN with plasma resistin levels and diabetes-related traits in the Framingham Offspring Study. Diabetes. 58: 750-6. PMID 19074981 DOI: 10.2337/Db08-1339  0.474
2009 Prokopenko I, Langenberg C, Florez JC, Saxena R, Soranzo N, Thorleifsson G, Loos RJ, Manning AK, Jackson AU, Aulchenko Y, Potter SC, Erdos MR, Sanna S, Hottenga JJ, Wheeler E, ... ... Dupuis J, et al. Variants in MTNR1B influence fasting glucose levels. Nature Genetics. 41: 77-81. PMID 19060907 DOI: 10.1038/Ng.290  0.449
2009 Kathiresan S, Willer CJ, Peloso GM, Demissie S, Musunuru K, Schadt EE, Kaplan L, Bennett D, Li Y, Tanaka T, Voight BF, Bonnycastle LL, Jackson AU, Crawford G, Surti A, ... ... Dupuis J, et al. Common variants at 30 loci contribute to polygenic dyslipidemia. Nature Genetics. 41: 56-65. PMID 19060906 DOI: 10.1038/Ng.291  0.354
2009 Liu C, Yang Q, Adrienne Cupples L, Meigs JB, Dupuis J. Selection of the most informative individuals from families with multiple siblings for association studies. Genetic Epidemiology. 33: 299-307. PMID 19025786 DOI: 10.1002/Gepi.20380  0.526
2008 Meigs JB, Shrader P, Sullivan LM, McAteer JB, Fox CS, Dupuis J, Manning AK, Florez JC, Wilson PW, D'Agostino RB, Cupples LA. Genotype score in addition to common risk factors for prediction of type 2 diabetes. The New England Journal of Medicine. 359: 2208-19. PMID 19020323 DOI: 10.1056/Nejmoa0804742  0.4
2008 Hivert MF, Manning AK, McAteer JB, Florez JC, Dupuis J, Fox CS, O'Donnell CJ, Cupples LA, Meigs JB. Common variants in the adiponectin gene (ADIPOQ) associated with plasma adiponectin levels, type 2 diabetes, and diabetes-related quantitative traits: the Framingham Offspring Study. Diabetes. 57: 3353-9. PMID 18776141 DOI: 10.2337/Db08-0700  0.455
2008 Meigs JB, Manning AK, Dupuis J, Liu C, Florez JC, Cupples LA. Ordered stratification to reduce heterogeneity in linkage to diabetes-related quantitative traits. Obesity (Silver Spring, Md.). 16: 2314-22. PMID 18719643 DOI: 10.1038/Oby.2008.354  0.515
2008 Liu C, Batliwalla F, Li W, Lee A, Roubenoff R, Beckman E, Khalili H, Damle A, Kern M, Furie R, Dupuis J, Plenge RM, Coenen MJ, Behrens TW, Carulli JP, et al. Genome-wide association scan identifies candidate polymorphisms associated with differential response to anti-TNF treatment in rheumatoid arthritis. Molecular Medicine (Cambridge, Mass.). 14: 575-81. PMID 18615156 DOI: 10.2119/2008-00056.Liu  0.537
2008 Schnabel R, Larson MG, Dupuis J, Lunetta KL, Lipinska I, Meigs JB, Yin X, Rong J, Vita JA, Newton-Cheh C, Levy D, Keaney JF, Vasan RS, Mitchell GF, Benjamin EJ. Relations of inflammatory biomarkers and common genetic variants with arterial stiffness and wave reflection. Hypertension. 51: 1651-7. PMID 18426996 DOI: 10.1161/Hypertensionaha.107.105668  0.313
2008 Stolerman ES, Manning AK, McAteer JB, Dupuis J, Fox CS, Cupples LA, Meigs JB, Florez JC. Haplotype structure of the ENPP1 Gene and Nominal Association of the K121Q missense single nucleotide polymorphism with glycemic traits in the Framingham Heart Study. Diabetes. 57: 1971-7. PMID 18426862 DOI: 10.2337/Db08-0266  0.473
2008 Cho K, Demissie S, Dupuis J, Cupples LA, Kathiresan S, Beck TJ, Karasik D, Kiel DP. Polymorphisms in the endothelial nitric oxide synthase gene and bone density/ultrasound and geometry in humans. Bone. 42: 53-60. PMID 17980690 DOI: 10.1016/J.Bone.2007.09.051  0.535
2007 Chen MH, Cui J, Guo CY, Cupples LA, Van Eerdewegh P, Dupuis J, Yang Q. Joint modeling of linkage and association using affected sib-pair data. Bmc Proceedings. 1: S38. PMID 18466536 DOI: 10.1186/1753-6561-1-S1-S38  0.598
2007 Cho K, Yang Q, Dupuis J. Handling linkage disequilibrium in linkage analysis using dense single-nucleotide polymorphisms. Bmc Proceedings. 1: S161. PMID 18466507 DOI: 10.1186/1753-6561-1-S1-S161  0.581
2007 Cordell HJ, de Andrade M, Babron MC, Bartlett CW, Beyene J, Bickeböller H, Culverhouse R, Cupples LA, Daw EW, Dupuis J, Falk CT, Ghosh S, Goddard KA, Goode EL, Hauser ER, et al. Genetic Analysis Workshop 15: gene expression analysis and approaches to detecting multiple functional loci. Bmc Proceedings. 1: S1. PMID 18466438 DOI: 10.1186/1753-6561-1-S1-S1  0.32
2007 Dupuis J, Siegmund DO, Yakir B. A unified framework for linkage and association analysis of quantitative traits. Proceedings of the National Academy of Sciences of the United States of America. 104: 20210-5. PMID 18077372 DOI: 10.1073/Pnas.0707138105  0.375
2007 Dupuis J, Albers K, Allen-Brady K, Cho K, Elston RC, Kappen HJ, Tang H, Thomas A, Thomson G, Tsung E, Yang Q, Zhang W, Zhao K, Zheng G, Ziegler JT. Effect of linkage disequilibrium between markers in linkage and association analyses. Genetic Epidemiology. 31: S139-48. PMID 18046770 DOI: 10.1002/Gepi.20291  0.612
2007 Yang Q, Biernacka JM, Chen MH, Houwing-Duistermaat JJ, Bergemann TL, Basu S, Fan R, Liu L, Bourgey M, Clerget-Darpoux F, Lin WY, Elston RC, Cupples LA, Apprey V, Cui J, ... Dupuis J, et al. Using linkage and association to identify and model genetic effects: summary of GAW15 Group 4. Genetic Epidemiology. 31: S34-42. PMID 18046758 DOI: 10.1002/Gepi.20278  0.573
2007 Fox CS, Heard-Costa N, Cupples LA, Dupuis J, Vasan RS, Atwood LD. Genome-wide association to body mass index and waist circumference: the Framingham Heart Study 100K project. Bmc Medical Genetics. 8: S18. PMID 17903300 DOI: 10.1186/1471-2350-8-S1-S18  0.375
2007 Meigs JB, Manning AK, Fox CS, Florez JC, Liu C, Cupples LA, Dupuis J. Genome-wide association with diabetes-related traits in the Framingham Heart Study. Bmc Medical Genetics. 8: S16. PMID 17903298 DOI: 10.1186/1471-2350-8-S1-S16  0.586
2007 Kiel DP, Demissie S, Dupuis J, Lunetta KL, Murabito JM, Karasik D. Genome-wide association with bone mass and geometry in the Framingham Heart Study. Bmc Medical Genetics. 8: S14. PMID 17903296 DOI: 10.1186/1471-2350-8-S1-S14  0.451
2007 Benjamin EJ, Dupuis J, Larson MG, Lunetta KL, Booth SL, Govindaraju DR, Kathiresan S, Keaney JF, Keyes MJ, Lin JP, Meigs JB, Robins SJ, Rong J, Schnabel R, Vita JA, et al. Genome-wide association with select biomarker traits in the Framingham Heart Study. Bmc Medical Genetics. 8: S11. PMID 17903293 DOI: 10.1186/1471-2350-8-S1-S11  0.439
2007 Cupples LA, Arruda HT, Benjamin EJ, D'Agostino RB, Demissie S, DeStefano AL, Dupuis J, Falls KM, Fox CS, Gottlieb DJ, Govindaraju DR, Guo CY, Heard-Costa NL, Hwang SJ, Kathiresan S, et al. The Framingham Heart Study 100K SNP genome-wide association study resource: overview of 17 phenotype working group reports. Bmc Medical Genetics. 8: S1. PMID 17903291 DOI: 10.1186/1471-2350-8-S1-S1  0.594
2007 Florez JC, Manning AK, Dupuis J, McAteer J, Irenze K, Gianniny L, Mirel DB, Fox CS, Cupples LA, Meigs JB. A 100K genome-wide association scan for diabetes and related traits in the Framingham Heart Study: replication and integration with other genome-wide datasets. Diabetes. 56: 3063-74. PMID 17848626 DOI: 10.2337/Db07-0451  0.461
2007 Karasik D, Dupuis J, Cupples LA, Beck TJ, Mahaney MC, Havill LM, Kiel DP, Demissie S. Bivariate linkage study of proximal hip geometry and body size indices: the Framingham study. Calcified Tissue International. 81: 162-73. PMID 17674073 DOI: 10.1007/S00223-007-9052-Y  0.322
2007 Maia AL, Dupuis J, Manning A, Liu C, Meigs JB, Cupples LA, Larsen PR, Fox CS. The type 2 deiodinase (DIO2) A/G polymorphism is not associated with glycemic traits: the Framingham Heart Study. Thyroid : Official Journal of the American Thyroid Association. 17: 199-202. PMID 17381351 DOI: 10.1089/Thy.2006.0298  0.538
2007 Dupuis J, O'Donnell CJ. Interpreting results of large-scale genetic association studies: Separating gold from fool's gold Journal of the American Medical Association. 297: 529-531. PMID 17284705 DOI: 10.1001/Jama.297.5.529  0.339
2006 Kiel DP, Ferrari SL, Cupples LA, Karasik D, Manen D, Imamovic A, Herbert AG, Dupuis J. Genetic variation at the low-density lipoprotein receptor-related protein 5 (LRP5) locus modulates Wnt signaling and the relationship of physical activity with bone mineral density in men. Bone. 40: 587-96. PMID 17137849 DOI: 10.1016/J.Bone.2006.09.029  0.398
2006 Demissie S, Dupuis J, Cupples LA, Beck TJ, Kiel DP, Karasik D. Proximal hip geometry is linked to several chromosomal regions: genome-wide linkage results from the Framingham Osteoporosis Study. Bone. 40: 743-50. PMID 17079199 DOI: 10.1016/J.Bone.2006.09.020  0.324
2006 Meigs JB, Dupuis J, Liu C, O'Donnell CJ, Fox CS, Kathiresan S, Gabriel SB, Larson MG, Yang Q, Herbert AG, Wilson PW, Feng D, Tofler GH, Cupples LA. PAI-1 Gene 4G/5G polymorphism and risk of type 2 diabetes in a population-based sample. Obesity (Silver Spring, Md.). 14: 753-8. PMID 16855181 DOI: 10.1038/Oby.2006.85  0.481
2006 Manichaikul A, Dupuis J, Sen S, Broman KW. Poor performance of bootstrap confidence intervals for the location of a quantitative trait locus. Genetics. 174: 481-9. PMID 16783000 DOI: 10.1534/Genetics.106.061549  0.404
2006 Sun C, Mathur P, Dupuis J, Tizard R, Ticho B, Crowell T, Gardner H, Bowcock AM, Carulli J. Peptidoglycan recognition proteins Pglyrp3 and Pglyrp4 are encoded from the epidermal differentiation complex and are candidate genes for the Psors4 locus on chromosome 1q21. Human Genetics. 119: 113-25. PMID 16362825 DOI: 10.1007/S00439-005-0115-8  0.422
2005 Chen MH, Van Eerdewegh P, Dupuis J. Identification of polymorphisms explaining a linkage signal: application to the GAW14 simulated data. Bmc Genetics. 6: S88. PMID 16451703 DOI: 10.1186/1471-2156-6-S1-S88  0.595
2005 Liu C, Cupples LA, Dupuis J. Comparisons of case-selection approaches based on allele sharing and/or disease severity index: application to the GAW14 simulated data. Bmc Genetics. 6: S103. PMID 16451559 DOI: 10.1186/1471-2156-6-S1-S103  0.515
2005 Dupuis J, Larson MG, Vasan RS, Massaro JM, Wilson PW, Lipinska I, Corey D, Vita JA, Keaney JF, Benjamin EJ. Genome scan of systemic biomarkers of vascular inflammation in the Framingham Heart Study: evidence for susceptibility loci on 1q. Atherosclerosis. 182: 307-14. PMID 16159603 DOI: 10.1016/J.Atherosclerosis.2005.02.015  0.336
2005 Guo CY, DeStefano AL, Lunetta KL, Dupuis J, Cupples LA. Expectation maximization algorithm based haplotype relative risk (EM-HRR): test of linkage disequilibrium using incomplete case-parents trios. Human Heredity. 59: 125-35. PMID 15867473 DOI: 10.1159/000085571  0.333
2005 Bureau A, Dupuis J, Falls K, Lunetta KL, Hayward B, Keith TP, Van Eerdewegh P. Identifying SNPs predictive of phenotype using random forests. Genetic Epidemiology. 28: 171-82. PMID 15593090 DOI: 10.1002/Gepi.20041  0.416
2005 Meigs JB, Dupuis J, Herbert AG, Liu C, Wilson PW, Cupples LA. The insulin gene variable number tandem repeat and risk of type 2 diabetes in a population-based sample of families and unrelated men and women. The Journal of Clinical Endocrinology and Metabolism. 90: 1137-43. PMID 15562019 DOI: 10.1210/Jc.2004-1212  0.515
2003 Bureau A, Dupuis J, Hayward B, Falls K, Van Eerdewegh P. Mapping complex traits using Random Forests. Bmc Genetics. S64. PMID 14975132 DOI: 10.1186/1471-2156-4-S1-S64  0.365
2003 Cahill P, Bakis M, Hurley J, Kamath V, Nielsen W, Weymouth D, Dupuis J, Doucette-Stamm L, Smith DR. Exo-proofreading, a versatile SNP scoring technology. Genome Research. 13: 925-31. PMID 12695330 DOI: 10.1101/Gr.939903  0.349
2002 Van Eerdewegh P, Little RD, Dupuis J, Del Mastro RG, Falls K, Simon J, Torrey D, Pandit S, McKenny J, Braunschweiger K, Walsh A, Liu Z, Hayward B, Folz C, Manning SP, et al. Association of the ADAM33 gene with asthma and bronchial hyperresponsiveness. Nature. 418: 426-30. PMID 12110844 DOI: 10.1038/Nature00878  0.341
2000 Dupuis J, Van Eerdewegh P. Multipoint linkage analysis of the pseudoautosomal regions, using affected sibling pairs American Journal of Human Genetics. 67: 462-475. PMID 10869236 DOI: 10.1086/303008  0.418
1998 Maheshwari HG, Silverman BL, Dupuis J, Baumann G. Phenotype and genetic analysis of a syndrome caused by an inactivating mutation in the growth hormone-releasing hormone receptor: Dwarfism of Sindh. The Journal of Clinical Endocrinology and Metabolism. 83: 4065-74. PMID 9814493 DOI: 10.1210/Jcem.83.11.5226  0.301
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