| Year |
Citation |
Score |
| 2018 |
Malik R, Di J, Nair G, Attar A, Taylor K, Teng E, Klärner FG, Schrader T, Bitan G. Using Molecular Tweezers to Remodel Abnormal Protein Self-Assembly and Inhibit the Toxicity of Amyloidogenic Proteins. Methods in Molecular Biology (Clifton, N.J.). 1777: 369-386. PMID 29744849 DOI: 10.1007/978-1-4939-7811-3_24 |
0.628 |
|
| 2017 |
Richter F, Subramaniam SR, Magen I, Lee P, Hayes J, Attar A, Zhu C, Franich NR, Bove N, De La Rosa K, Kwong J, Klärner FG, Schrader T, Chesselet MF, Bitan G. A Molecular Tweezer Ameliorates Motor Deficits in Mice Overexpressing α-Synuclein. Neurotherapeutics : the Journal of the American Society For Experimental Neurotherapeutics. PMID 28585223 DOI: 10.1007/S13311-017-0544-9 |
0.618 |
|
| 2015 |
Lopes DH, Attar A, Nair G, Hayden EY, Du Z, McDaniel K, Dutt S, Bravo-Rodriguez K, Mittal S, Klärner FG, Wang C, Sanchez-Garcia E, Schrader T, Bitan G. Molecular Tweezers Inhibit Islet Amyloid Polypeptide Assembly and Toxicity by a New Mechanism. Acs Chemical Biology. 10: 1555-69. PMID 25844890 DOI: 10.1021/Acschembio.5B00146 |
0.63 |
|
| 2014 |
Attar A, Chan WT, Klärner FG, Schrader T, Bitan G. Safety and pharmacological characterization of the molecular tweezer CLR01 - a broad-spectrum inhibitor of amyloid proteins' toxicity. Bmc Pharmacology & Toxicology. 15: 23. PMID 24735982 DOI: 10.1186/2050-6511-15-23 |
0.644 |
|
| 2014 |
Acharya S, Safaie BM, Wongkongkathep P, Ivanova MI, Attar A, Klärner FG, Schrader T, Loo JA, Bitan G, Lapidus LJ. Molecular basis for preventing α-synuclein aggregation by a molecular tweezer. The Journal of Biological Chemistry. 289: 10727-37. PMID 24567327 DOI: 10.1074/Jbc.M113.524520 |
0.613 |
|
| 2014 |
Ferreira N, Pereira-Henriques A, Attar A, Klärner FG, Schrader T, Bitan G, Gales L, Saraiva MJ, Almeida MR. Molecular tweezers targeting transthyretin amyloidosis. Neurotherapeutics : the Journal of the American Society For Experimental Neurotherapeutics. 11: 450-61. PMID 24459092 DOI: 10.1007/S13311-013-0256-8 |
0.678 |
|
| 2014 |
Attar A, Bitan G. Disrupting self-assembly and toxicity of amyloidogenic protein oligomers by "molecular tweezers" - from the test tube to animal models. Current Pharmaceutical Design. 20: 2469-83. PMID 23859557 DOI: 10.2174/13816128113199990496 |
0.659 |
|
| 2014 |
Attar A. In vivo characterization of CLR01, an aggregation and toxicity inhibitor, with an Alzheimer's disease focus Rejuvenation Research. 17: 313-314. DOI: 10.1089/rej.2014.1578 |
0.415 |
|
| 2013 |
Attar A, Liu T, Chan WT, Hayes J, Nejad M, Lei K, Bitan G. A shortened Barnes maze protocol reveals memory deficits at 4-months of age in the triple-transgenic mouse model of Alzheimer's disease. Plos One. 8: e80355. PMID 24236177 DOI: 10.1371/Journal.Pone.0080355 |
0.56 |
|
| 2013 |
Attar A, Rahimi F, Bitan G. Modulators of amyloid protein aggregation and toxicity: EGCG and CLR01 Translational Neuroscience. 4: 385-409. DOI: 10.2478/S13380-013-0137-Y |
0.724 |
|
| 2013 |
Attar A, Meral D, Urbanc B, Bitan G. Assembly of Amyloid β-Protein Variants Containing Familial Alzheimer's Disease-Linked Amino Acid Substitutions Bio-Nanoimaging: Protein Misfolding and Aggregation. 429-442. DOI: 10.1016/B978-0-12-394431-3.00038-9 |
0.588 |
|
| 2012 |
Attar A, Ripoli C, Riccardi E, Maiti P, Li Puma DD, Liu T, Hayes J, Jones MR, Lichti-Kaiser K, Yang F, Gale GD, Tseng CH, Tan M, Xie CW, Straudinger JL, et al. Protection of primary neurons and mouse brain from Alzheimer's pathology by molecular tweezers. Brain : a Journal of Neurology. 135: 3735-48. PMID 23183235 DOI: 10.1093/Brain/Aws289 |
0.737 |
|
| 2012 |
Prabhudesai S, Sinha S, Attar A, Kotagiri A, Fitzmaurice AG, Lakshmanan R, Lakshmanan R, Ivanova MI, Loo JA, Klärner FG, Schrader T, Stahl M, Bitan G, Bronstein JM. A novel "molecular tweezer" inhibitor of α-synuclein neurotoxicity in vitro and in vivo. Neurotherapeutics : the Journal of the American Society For Experimental Neurotherapeutics. 9: 464-76. PMID 22373667 DOI: 10.1007/S13311-012-0105-1 |
0.734 |
|
| 2012 |
Attar A, Ripoli C, Riccardi E, Maiti P, Liu T, Jones M, Yang F, Tseng C, Klärner F, Schrader T, Frautschy S, Grassi C, Bitan G. O2-12-01: Lysine-specific molecular tweezers protect neurons against beta-amyloid-induced synaptotoxicity and lower beta-amyloid and p-tau load in a mouse model of Alzheimer's disease Alzheimer's & Dementia. 8: P259-P259. DOI: 10.1016/J.Jalz.2012.05.690 |
0.62 |
|
| 2012 |
Prabhudesai S, Sinha S, Attar A, Kotagiri A, Fitzmaurice AG, Lakshmanan R, Ivanova MI, Loo JA, Klärner F, Schrader T, Stahl M, Bitan G, Bronstein JM. Erratum to: A Novel “Molecular Tweezer” Inhibitor of α-Synuclein Neurotoxicity In Vitro and In Vivo Neurotherapeutics. 9: 486-486. DOI: 10.1007/S13311-012-0120-2 |
0.673 |
|
| 2011 |
Moskovitz J, Maiti P, Lopes DH, Oien DB, Attar A, Liu T, Mittal S, Hayes J, Bitan G. Induction of methionine-sulfoxide reductases protects neurons from amyloid β-protein insults in vitro and in vivo. Biochemistry. 50: 10687-97. PMID 22059533 DOI: 10.1021/Bi201426B |
0.69 |
|
| 2010 |
Attar A, Sinha S, Maiti P, Yang F, Gant D, Jones M, Talbiersky P, Schrader T, Klärner F, Frautschy S, Bitan G. P4-100: Small Molecule Inhibitor of Amyloid beta-protein Oligomerization Reduces Brain Abeta Load in an Alzheimer's Disease Mouse Model Alzheimer's & Dementia. 6: e51-e51. DOI: 10.1016/J.Jalz.2010.08.158 |
0.729 |
|
| 2010 |
Bitan G, Sinha S, Attar A, Maiti P, Tan M, Prabhudesai S, Talbiersky P, Bakshi R, Kuo P, Yang F, Gant D, Jones MR, Xie C, Bronstein JM, Frautschy SA, et al. O3-07-02: Novel, small molecule inhibitors of protein aggregation for treatment of amyloid-related diseases Alzheimer's & Dementia. 6: S142-S142. DOI: 10.1016/J.Jalz.2010.05.436 |
0.71 |
|
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