Robert S. Lees, M.D. - Publications

Affiliations: 
Health Sciences and Technology Massachusetts Institute of Technology, Cambridge, MA, United States 
Website:
https://connects.catalyst.harvard.edu/Profiles/display/Person/51858

68 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2007 Lees RS. Prevention of atherosclerosis progression in asymptomatic healthy elderly. The American Journal of Clinical Nutrition. 86: 1569S-71S. PMID 17991677 DOI: 10.1093/Ajcn/86.5.1569S  0.309
2006 Lo J, Dolan SE, Kanter JR, Hemphill LC, Connelly JM, Lees RS, Grinspoon SK. Effects of obesity, body composition, and adiponectin on carotid intima-media thickness in healthy women. The Journal of Clinical Endocrinology and Metabolism. 91: 1677-82. PMID 16522690 DOI: 10.1097/01.Ogx.0000238644.07119.Ba  0.3
2005 Lees AM, Deconinck AE, Campbell BD, Lees RS. Atherin: a newly identified, lesion-specific, LDL-binding protein in human atherosclerosis. Atherosclerosis. 182: 219-30. PMID 16159594 DOI: 10.1016/J.Atherosclerosis.2005.01.041  0.36
2001 Lees AM, Veys JA, Lees RS. Reversible and irreversible non-internalized LDL and methyl LDL accumulation by human fibroblasts. Atherosclerosis. 157: 65-74. PMID 11427205 DOI: 10.1016/S0021-9150(00)00707-3  0.421
2000 Cashin-Hemphill L, Noone M, Abbott JF, Waksmonski CA, Lees RS. Low-density lipoprotein apheresis therapy during pregnancy. The American Journal of Cardiology. 86: 1160, A10. PMID 11074223 DOI: 10.1016/S0002-9149(00)01183-8  0.34
1999 Lees RS, Cashin-Hemphill L, Lees AM. Non-pharmacological lowering of low-density lipoprotein by apheresis and surgical techniques. Current Opinion in Lipidology. 10: 575-9. PMID 10680051 DOI: 10.1097/00041433-199912000-00012  0.32
1997 Brennan JF, Römer TJ, Lees RS, Tercyak AM, Kramer JR, Feld MS. Determination of human coronary artery composition by Raman spectroscopy. Circulation. 96: 99-105. PMID 9236423 DOI: 10.1161/01.Cir.96.1.99  0.323
1997 Stadler RW, Ibrahim SF, Lees RS. Peripheral vasoactivity in familial hypercholesterolemic subjects treated with heparin-induced extracorporeal LDL precipitation (HELP). Atherosclerosis. 128: 241-9. PMID 9050781 DOI: 10.1016/S0021-9150(96)05998-9  0.358
1996 Lu P, Zanzonico P, Lister-James J, Goldfine SM, Herrold E, Lees RS, Lees AM, Dean RT, Moyer BR, Borer JS. Biodistribution and autoradiographic localization of I-125--labeled synthetic Peptide in aortic atherosclerosis in cholesterol-fed rabbits. American Journal of Therapeutics. 3: 673-80. PMID 11862222 DOI: 10.1097/00045391-199610000-00002  0.403
1996 Stadler RW, Karl WC, Lees RS. The application of echo-tracking methods to endothelium-dependent vasoreactivity and arterial compliance measurements. Ultrasound in Medicine & Biology. 22: 35-42. PMID 8928315 DOI: 10.1016/0301-5629(95)02018-7  0.303
1996 Stadler RW, Karl WC, Lees RS. New methods for arterial diameter measurement from B-mode images. Ultrasound in Medicine & Biology. 22: 25-34. PMID 8928314 DOI: 10.1016/0301-5629(95)02017-9  0.316
1996 Lees RS, Pitt B, Chan RC, Holmvang G, Dinsmore RE, Campbell LW, Haber HE, Klibaner MI, Cashin-Hemphill L. Baseline clinical and angiographic data in the Quinapril Ischemic Event (QUIET) Trial. The American Journal of Cardiology. 78: 1011-6. PMID 8916480 DOI: 10.1016/S0002-9149(96)00526-7  0.347
1996 Lees RS, Holmes NN, Stadler RW, Ibrahim SF, Lees AM. Treatment of hypercholesterolemia with heparin-induced extracorporeal low-density lipoprotein precipitation (HELP). Journal of Clinical Apheresis. 11: 132-7. PMID 8915817 DOI: 10.1002/(Sici)1098-1101(1996)11:3<132::Aid-Jca3>3.0.Co;2-C  0.372
1995 Hardoff R, Zanzonico P, Braegelmann F, Herrold EM, Lees RS, Lees AM, Dean RT, Lister-James J, Borer JS. Localization of (99m)Tc-Labeled ApoB Synthetic Peptide in Arterial Lesions of an Experimental Model of Spontaneous Atherosclerosis. American Journal of Therapeutics. 2: 88-99. PMID 11847534 DOI: 10.1097/00045391-199502000-00003  0.302
1994 Lees A, Veys J, Lees R. An in vitro model for LDL trapping in arterial lesions Atherosclerosis. 109: 195-196. DOI: 10.1016/0021-9150(94)93785-0  0.312
1993 Labeque R, Mullon CJP, Ferreira JPM, Lees RS, Langer R. Enzymatic modification of plasma low density lipoproteins in rabbits: A potential treatment for hypercholesterolemia Proceedings of the National Academy of Sciences of the United States of America. 90: 3476-3480. PMID 8475095 DOI: 10.1073/Pnas.90.8.3476  0.391
1993 Lees RS. Low-density lipoprotein modification and arterial wall accumulation in a rabbit model of atherosclerosis Biochemistry. 32: 8518-8524. PMID 8357798 DOI: 10.1021/Bi00084A018  0.432
1992 Chang MY, Lees AM, Lees RS. Time course of125I-labeled LDL accumulation in the healing, balloon-deendothelialized rabbit aorta Arteriosclerosis, Thrombosis, and Vascular Biology. 12: 1088-1098. PMID 1525124 DOI: 10.1161/01.Atv.12.9.1088  0.485
1992 Labeque R, Clark BM, Ferreira J, Langer R, Mullon CJP, Lees RS. Phospholipase A2-catalysed modification of plasma low density lipoproteins caused reduction of hypercholesterolemic rabbit plasma cholesterol in vivo Journal of Materials Science: Materials in Medicine. 3: 5-9. DOI: 10.1007/Bf00702937  0.403
1990 Shih IL, Lees RS, Chang MY, Lees AM. Focal accumulation of an apolipoprotein B-based synthetic oligopeptide in the healing rabbit arterial wall Proceedings of the National Academy of Sciences of the United States of America. 87: 1436-1440. PMID 2304909 DOI: 10.1073/Pnas.87.4.1436  0.345
1988 Lees RS. Method and means for detection of arterial lesions International Journal of Radiation Applications and Instrumentation. Part B. Nuclear Medicine and Biology. 15: iii. DOI: 10.1016/0883-2897(88)90176-6  0.362
1987 Fischman AJ, Lees AM, Lees RS, Barlai-Kovach M, Strauss HW. Accumulation of native and methylated low density lipoproteins by healing rabbit arterial wall Arteriosclerosis. 7: 361-366. PMID 3606463 DOI: 10.1161/01.Atv.7.4.361  0.446
1986 Isaacsohn JL, Lees AM, Lees RS, William Strauss H, Barlai-Kovach M, Moore TJ. Adrenal imaging with technetium-99m-labelled low density lipoproteins Metabolism. 35: 364-366. PMID 3959906 DOI: 10.1016/0026-0495(86)90156-3  0.392
1986 Stemerman MB, Morrel EM, Burke KR, Colton CK, Smith KA, Lees RS. Local variation in arterial wall permeability to low density lipoprotein in normal rabbit aorta. Arteriosclerosis (Dallas, Tex.). 6: 64-9. PMID 3942560 DOI: 10.1161/01.Atv.6.1.64  0.695
1984 Ramirez CA, Colton CK, Smith KA, Stemerman MB, Lees RS. Transport of 125I-albumin across normal and deendothelialized rabbit thoracic aorta in vivo. Arteriosclerosis (Dallas, Tex.). 4: 283-91. PMID 6712542 DOI: 10.1161/01.Atv.4.3.283  0.693
1983 Chisolm GM, Bohrer MP, Colton CK, Smith KA, Lees RS. Transmural [125I]albumin concentration in the rabbit aorta during acute hypoxia. Atherosclerosis. 46: 195-202. PMID 6838699 DOI: 10.1016/0021-9150(83)90110-7  0.68
1983 Roberts AB, Lees AM, Lees RS, Strauss HW, Fallon JT, Taveras J, Kopiwoda S. Selective accumulation of low density lipoproteins in damaged arterial wall Journal of Lipid Research. 24: 1160-1167. PMID 6631245  0.333
1983 Lees AM, Lees RS. Low density lipoprotein degradation by mononuclear cells from normal and dyslipoproteinemic subjects Proceedings of the National Academy of Sciences of the United States of America. 80: 5098-5102. PMID 6576379 DOI: 10.1073/Pnas.80.16.5098  0.381
1983 Illingworth DR, Lees AM, Lees RS. Adrenal cortical function in homozygous familial hypercholesterolemia Metabolism. 32: 1045-1052. PMID 6312250 DOI: 10.1016/0026-0495(83)90075-6  0.361
1982 Feig LA, Peppas NA, Colton CK, Smith KA, Lees RS. The effect of angiotensin II on in vivo albumin transport in normal rabbit aortic tissue. Atherosclerosis. 44: 307-18. PMID 7150395 DOI: 10.1016/0021-9150(82)90005-3  0.675
1981 Killner MS, Lees RS. High molecular weight fibrinogen derivatives in hyperlipidemia Thrombosis Research. 22: 329-344. PMID 7302902 DOI: 10.1016/0049-3848(81)90126-2  0.373
1981 Kistler JP, Lees RS, Miller A, Crowell RM, Roberson G. Correlation of spectral phonoangiography and carotid angiography with gross pathology in carotid stenosis. The New England Journal of Medicine. 305: 417-9. PMID 7254278 DOI: 10.1056/Nejm198108203050801  0.321
1981 Ramírez CA, Stemerman MB, Isaacson KA, Colton CK, Smith KA, Lees RS. Morphological and morphometric characterization of platelet adhesion to the exposed subendothelium of the rabbit thoracic aorta in vivo. Microvascular Research. 21: 320-31. PMID 7242382 DOI: 10.1016/0026-2862(81)90015-7  0.617
1981 Aviram M, Brook JG, Lees AM, Lees RS. Low density lipoprotein binding to human platelets: Role of charge and of specific amino acids Biochemical and Biophysical Research Communications. 99: 308-318. PMID 7236268 DOI: 10.1016/0006-291X(81)91746-0  0.352
1980 Miller A, Lees RS, Kistler JP, Abbott WM. Effects of surrounding tissue on the sound spectrum of arterial bruits in vivo. Stroke; a Journal of Cerebral Circulation. 11: 394-8. PMID 7414668 DOI: 10.1161/01.Str.11.4.394  0.344
1980 King MEE, Breslow JL, Lees RS. Plasma-exchange therapy of homozygous familial hypercholesterolemia New England Journal of Medicine. 302: 1457-1459. PMID 7374711 DOI: 10.1056/Nejm198006263022607  0.352
1980 Carvalho ACA, Lees RS. Platelets, intravascular coagulation and fibrinolysis in hyperlipidaemias: Relationship to thrombo-embolic complications Acta Medica Scandinavica. 208: 101-112. PMID 6935936 DOI: 10.1111/J.0954-6820.1980.Tb10941.X  0.319
1979 Glickman RM, Green PHR, Lees RS, Lux SE, Kilgore A. Immunofluorescence studies of apolipoprotein B in intestinal mucosa. Absence in abetalipoproteinemia Gastroenterology. 76: 288-292. PMID 365664 DOI: 10.1016/0016-5085(79)90335-4  0.321
1979 Brook JG, Torsvik H, Lees RS, McCluskey MA, Feldman HA. Low density lipoprotein metabolism in type IV and type V hyperlipoproteinemia. Metabolism: Clinical and Experimental. 28: 4-8. PMID 215869 DOI: 10.1016/0026-0495(79)90161-6  0.363
1979 Glickman RM, Green PHR, Lees RS, Lux SE, Kilgore A. Immunofluorescence studies of apolipoprotein B in intestinal mucosa Gastroenterology. 76: 288-292. DOI: 10.5555/Uri:Pii:0016508579903354  0.32
1978 Lees RS, Carvalho AC. Hypercholesterolemia and platelets Advances in Experimental Medicine and Biology. 104: 301-308. PMID 717140 DOI: 10.1007/978-1-4684-7787-0_18  0.358
1978 Tall AR, Small DM, Lees RS. Interaction of collagen with the lipids of tendon xanthomata Journal of Clinical Investigation. 62: 836-846. PMID 701482 DOI: 10.1172/Jci109196  0.335
1978 Kistler JP, Lees RS, Friedman J, Pressin M, Mohr JP, Roberson GS, Ojemann RG. The bruit of carotid stenosis versus radiated basal heart murmurs. Differentiation by phonoangiography. Circulation. 57: 975-81. PMID 639219 DOI: 10.1161/01.Cir.57.5.975  0.309
1978 Apstein CS, Zilversmit DB, Lees RS, George PK. Effect of intensive plasmapheresis on the plasma cholesterol concentration with familial hypercholesterolemia Atherosclerosis. 31: 105-115. PMID 215170 DOI: 10.1016/0021-9150(78)90157-0  0.389
1978 Glickman RM, Green PHR, Lees RS, Tall A. Apoprotein A-I synthesis in normal intestinal mucosa and in Tangier disease New England Journal of Medicine. 299: 1424-1427. PMID 213720 DOI: 10.1056/Nejm197812282992602  0.329
1977 Bratzler RL, Chisolm GM, Colton CK, Smith KA, Zilversmit DB, Lees RS. The distribution of labeled albumin across the rabbit thoracic aorta in vivo. Circulation Research. 40: 182-90. PMID 844144  0.713
1977 Deckelbaum RJ, Lees RS, Small DM, Hedberg SE, Grundy SM. Failure of complete bile diversion and oral bile acid therapy in the treatment of homozygous familial hypercholesterolemia New England Journal of Medicine. 296: 465-470. PMID 834224 DOI: 10.1056/Nejm197703032960901  0.308
1977 Carvalho AC, Lees RS, Vaillancourt RA, Colman RW. Effect of clofibrate on intravascular coagulation in hyperlipoproteinemia Circulation. 56: 114-118. PMID 301067 DOI: 10.1161/01.Cir.56.1.114  0.306
1977 Bratzler RL, Chisolm GM, Colton CK, Smith KA, Lees RS. The distribution of labeled low-density lipoproteins across the rabbit thoracic aorta in vivo. Atherosclerosis. 28: 289-307. PMID 202290 DOI: 10.1016/0021-9150(77)90177-0  0.715
1977 Katz SS, Small DM, Brook JG, Lees RS. The storage lipids in Tangier disease. A physical chemical study Journal of Clinical Investigation. 59: 1045-1054. PMID 193870 DOI: 10.1172/Jci108727  0.33
1977 Carvalho ACA, Colman RW, Lees RS, Vaillancourt RA, Cabral RB. Coagulation Abnormalities in Women Taking Oral Contraceptives Jama: the Journal of the American Medical Association. 237: 875-878. DOI: 10.1001/Jama.1977.03270360037014  0.302
1976 Lees RS, Lees AM. Therapy of the hyperlipidemias Postgraduate Medicine. 60: 99-107. PMID 959087 DOI: 10.1080/00325481.1976.11712083  0.331
1976 Lees AM, McCluskey MA, Lees RS. Results of colestipol therapy in Type II hyperlipoproteinemia. Atherosclerosis. 24: 129-40. PMID 182181 DOI: 10.1016/0021-9150(76)90070-8  0.321
1976 Carvalho AC, Lees RS, Vaillancourt RA, Cabral RB, Weinberg RM, Colman RW. Intravascular coagulation in hyperlipidemia Thrombosis Research. 8: 843-857. DOI: 10.1016/0049-3848(76)90013-X  0.307
1975 Tall AR, Small DM, Shipley GG, Lees RS. Apoprotein stability and lipid protein interactions in human plasma high density lipoproteins Proceedings of the National Academy of Sciences of the United States of America. 72: 4940-4942. PMID 174082 DOI: 10.1073/Pnas.72.12.4940  0.34
1975 Deckelbaum RJ, Shipley GG, Small DM, Lees RS, George PK. Thermal transitions in human plasma low density lipoproteins. Science (New York, N.Y.). 190: 392-4. PMID 170681 DOI: 10.1126/Science.170681  0.339
1975 Breslow JL, Spaulding DR, Lux SE, Levy RI, Lees RS. Homozygous familial hypercholesterolemia. A possible biochemical explanation of clinical heterogeneity New England Journal of Medicine. 293: 900-903. PMID 170518 DOI: 10.1056/Nejm197510302931804  0.315
1975 Duncan GW, Gruber JO, Dewey CF, Myers GS, Lees RS. Evaluation of carotid stenosis by phonoangiography. The New England Journal of Medicine. 293: 1124-8. PMID 127121 DOI: 10.1056/Nejm197511272932205  0.353
1974 Carvalho ACA, Colman RW, Lees RS. Clofibrate reversal of platelet hypersensitivity in hyperbetalipoproteinemia Circulation. 50: 570-574. PMID 4369866 DOI: 10.1161/01.Cir.50.3.570  0.356
1974 Schonfeld G, Lees RS, George PK, Pfleger B. Assay of total plasma apolipoprotein B concentration in human subjects Journal of Clinical Investigation. 53: 1458-1467. PMID 4363408 DOI: 10.1172/Jci107694  0.396
1972 Lees RS, Fiser RH, Beisel WR, Bartelloni PJ. Effects of an experimental viral infection on plasma lipid and lipoprotein metabolism Metabolism. 21: 825-833. PMID 4626894 DOI: 10.1016/0026-0495(72)90005-4  0.375
1972 Colton CK, Friedman S, Wilson DE, Lees RS. Ultrafiltration of lipoproteins through a synthetic membrane. Implications for the filtration theory of atherogenesis. The Journal of Clinical Investigation. 51: 2472-81. PMID 4344733 DOI: 10.1172/Jci107061  0.605
1972 Wilson DE, Lees RS. Metabolic relationships among the plasma lipoproteins. Reciprocal changes in the concentrations of very low and low density lipoproteins in man. The Journal of Clinical Investigation. 51: 1051-7. PMID 4341500 DOI: 10.1172/Jci106896  0.408
1971 Lees RS, Wilson DE. The treatment of hyperlipidemia. The New England Journal of Medicine. 284: 186-95. PMID 4923684 DOI: 10.1056/Nejm197101282840406  0.415
1970 Lees RS. Immunoassay of plasma low-density lipoproteins Science. 169: 493-495. PMID 5424796 DOI: 10.1126/Science.169.3944.493  0.392
1970 Lees RS, Dewey CF. Phonoangiography: a new noninvasive diagnostic method for studying arterial disease Proceedings of the National Academy of Sciences of the United States of America. 67: 935-942. PMID 5289030 DOI: 10.1073/Pnas.67.2.935  0.314
1967 Fredrickson DS, Levy RI, Lees RS. Fat Transport in Lipoproteins — An Integrated Approach to Mechanisms and Disorders The New England Journal of Medicine. 276: 148-156. PMID 5334266 DOI: 10.1056/Nejm196701192760305  0.32
1966 HATCH FT, REISSELL PK, POON-KING TMW, CANELLOS GP, LEES RS, HAGOPIAN LM. A Study of Coronary Heart Disease in Young Men Circulation. 33: 679-703. DOI: 10.1161/01.Cir.33.5.679  0.331
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