Reuben S. Harris - Publications

Affiliations: 
Biochemistry, Molecular Bio, and Biophysics University of Minnesota, Twin Cities, Minneapolis, MN 
Area:
Virology Biology, Molecular Biology

111 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 McCann JM, Klein MM, Leland EM, Law EK, Brown WL, Salamango DJ, Harris RS. The DNA deaminase APOBEC3B interacts with the cell cycle protein CDK4 and disrupts CDK4-mediated nuclear import of Cyclin D1. The Journal of Biological Chemistry. PMID 31217276 DOI: 10.1074/jbc.RA119.008443  0.68
2019 Ikeda T, Molan AM, Jarvis MC, Carpenter MA, Salamango DJ, Brown WL, Harris RS. HIV-1 restriction by endogenous APOBEC3G in the myeloid cell line THP-1. The Journal of General Virology. PMID 31145054 DOI: 10.1099/jgv.0.001276  0.68
2018 Carpenter MA, Law EK, Serebrenik A, Brown WL, Harris RS. A lentivirus-based system for Cas9/gRNA expression and subsequent removal by Cre-mediated recombination. Methods (San Diego, Calif.). PMID 30578845 DOI: 10.1016/j.ymeth.2018.12.006  0.68
2018 Anderson BD, Ikeda T, Moghadasi SA, Martin AS, Brown WL, Harris RS. Natural APOBEC3C variants can elicit differential HIV-1 restriction activity. Retrovirology. 15: 78. PMID 30558640 DOI: 10.1186/s12977-018-0459-5  0.68
2018 Cheng AZ, Yockteng-Melgar J, Jarvis MC, Malik-Soni N, Borozan I, Carpenter MA, McCann JL, Ebrahimi D, Shaban NM, Marcon E, Greenblatt J, Brown WL, Frappier L, Harris RS. Epstein-Barr virus BORF2 inhibits cellular APOBEC3B to preserve viral genome integrity. Nature Microbiology. PMID 30420783 DOI: 10.1038/s41564-018-0284-6  0.68
2018 Ebrahimi D, Richards CM, Carpenter MA, Wang J, Ikeda T, Becker JT, Cheng AZ, McCann JL, Shaban NM, Salamango DJ, Starrett GJ, Lingappa JR, Yong J, Brown WL, Harris RS. Genetic and mechanistic basis for APOBEC3H alternative splicing, retrovirus restriction, and counteraction by HIV-1 protease. Nature Communications. 9: 4137. PMID 30297863 DOI: 10.1038/s41467-018-06594-3  0.68
2018 Salamango DJ, Becker JT, McCann JL, Cheng AZ, Demir Ö, Amaro RE, Brown WL, Shaban NM, Harris RS. APOBEC3H Subcellular Localization Determinants Define Zipcode for Targeting HIV-1 for Restriction. Molecular and Cellular Biology. PMID 30224517 DOI: 10.1128/MCB.00356-18  0.68
2018 Jarvis MC, Ebrahimi D, Temiz NA, Harris RS. Mutation Signatures Including APOBEC in Cancer Cell Lines. Jnci Cancer Spectrum. 2. PMID 29888758 DOI: 10.1093/jncics/pky002  0.44
2018 Salamango DJ, McCann JL, Demir Ö, Brown WL, Amaro RE, Harris RS. APOBEC3B Nuclear Localization Requires two Distinct N-Terminal Domain Surfaces. Journal of Molecular Biology. PMID 29787764 DOI: 10.1016/j.jmb.2018.04.044  0.68
2018 St Martin A, Salamango D, Serebrenik A, Shaban N, Brown WL, Donati F, Munagala U, Conticello SG, Harris RS. A fluorescent reporter for quantification and enrichment of DNA editing by APOBEC-Cas9 or cleavage by Cas9 in living cells. Nucleic Acids Research. PMID 29746667 DOI: 10.1093/nar/gky332  0.68
2018 Wang J, Shaban NM, Land AM, Brown WL, Harris RS. SIVVif and Human APOBEC3B Interactions Resemble Those Between HIV-1 Vif and Human APOBEC3G. Journal of Virology. PMID 29618650 DOI: 10.1128/JVI.00447-18  0.68
2017 Shaban NM, Shi K, Lauer KV, Carpenter MA, Richards CM, Salamango D, Wang J, Lopresti MW, Banerjee S, Levin-Klein R, Brown WL, Aihara H, Harris RS. The Antiviral and Cancer Genomic DNA Deaminase APOBEC3H Is Regulated by an RNA-Mediated Dimerization Mechanism. Molecular Cell. PMID 29290613 DOI: 10.1016/j.molcel.2017.12.010  0.68
2017 Molan AM, Hanson HM, Chweya CM, Anderson BD, Starrett GJ, Richards CM, Harris RS. APOBEC3B lysine residues are dispensable for DNA cytosine deamination, HIV-1 restriction, and nuclear localization. Virology. 511: 74-81. PMID 28841445 DOI: 10.1016/j.virol.2017.08.025  0.6
2016 Pan Y, Sun Z, Maiti A, Kanai T, Matsuo H, Li M, Harris RS, Shlyakhtenko LS, Lyubchenko YL. Nanoscale Characterization of Interaction of APOBEC3G with RNA. Biochemistry. PMID 28029777 DOI: 10.1021/acs.biochem.6b01189  0.36
2016 Shi K, Carpenter MA, Banerjee S, Shaban NM, Kurahashi K, Salamango DJ, McCann JL, Starrett GJ, Duffy JV, Demir Ö, Amaro RE, Harki DA, Harris RS, Aihara H. Structural basis for targeted DNA cytosine deamination and mutagenesis by APOBEC3A and APOBEC3B. Nature Structural & Molecular Biology. PMID 27991903 DOI: 10.1038/nsmb.3344  0.44
2016 Harris RS, Anderson BD. Evolutionary Paradigms from Ancient and Ongoing Conflicts between the Lentiviral Vif Protein and Mammalian APOBEC3 Enzymes. Plos Pathogens. 12: e1005958. PMID 27907174 DOI: 10.1371/journal.ppat.1005958  0.6
2016 Law EK, Sieuwerts AM, LaPara K, Leonard B, Starrett GJ, Molan AM, Temiz NA, Vogel RI, Meijer-van Gelder ME, Sweep FC, Span PN, Foekens JA, Martens JW, Yee D, Harris RS. The DNA cytosine deaminase APOBEC3B promotes tamoxifen resistance in ER-positive breast cancer. Science Advances. 2: e1601737. PMID 27730215 DOI: 10.1126/sciadv.1601737  0.52
2016 Starrett GJ, Luengas EM, McCann JL, Ebrahimi D, Temiz NA, Love RP, Feng Y, Adolph MB, Chelico L, Law EK, Carpenter MA, Harris RS. The DNA cytosine deaminase APOBEC3H haplotype I likely contributes to breast and lung cancer mutagenesis. Nature Communications. 7: 12918. PMID 27650891 DOI: 10.1038/ncomms12918  0.92
2016 Shlyakhtenko LS, Dutta S, Li M, Harris RS, Lyubchenko YL. Single-Molecule Force Spectroscopy Studies of APOBEC3A-ssDNA Complexes. Biochemistry. PMID 27182892 DOI: 10.1021/acs.biochem.6b00214  0.92
2016 Akre MK, Starrett GJ, Quist JS, Temiz NA, Carpenter MA, Tutt AN, Grigoriadis A, Harris RS. Mutation Processes in 293-Based Clones Overexpressing the DNA Cytosine Deaminase APOBEC3B. Plos One. 11: e0155391. PMID 27163364 DOI: 10.1371/journal.pone.0155391  0.92
2016 Shaban NM, Shi K, Li M, Aihara H, Harris RS. 1.92 Angstrom Zinc-Free APOBEC3F Catalytic Domain Crystal Structure. Journal of Molecular Biology. PMID 27139641 DOI: 10.1016/j.jmb.2016.04.026  0.92
2016 Leonard B, Starrett GJ, Maurer MJ, Oberg A, Van Bockstal M, Van Dorpe J, De Wever O, Helleman J, Sieuwerts AM, Berns EM, Martens JW, Anderson B, Brown WL, Kalli KR, Kaufmann SH, ... Harris RS, et al. APOBEC3G expression correlates with T cell infiltration and improved clinical outcomes in high-grade serous ovarian carcinoma. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 27016308 DOI: 10.1158/1078-0432.CCR-15-2910  0.68
2015 Richards C, Albin JS, Demir Ö, Shaban NM, Luengas EM, Land AM, Anderson BD, Holten JR, Anderson JS, Harki DA, Amaro RE, Harris RS. The Binding Interface between Human APOBEC3F and HIV-1 Vif Elucidated by Genetic and Computational Approaches. Cell Reports. PMID 26628363 DOI: 10.1016/j.celrep.2015.10.067  0.92
2015 Anderson BD, Harris RS. Transcriptional regulation of APOBEC3 antiviral immunity through the CBF-β/RUNX axis. Science Advances. 1: e1500296. PMID 26601257 DOI: 10.1126/sciadv.1500296  0.6
2015 Land AM, Wang J, Law EK, Aberle R, Kirmaier A, Krupp A, Johnson WE, Harris RS. Degradation of the cancer genomic DNA deaminase APOBEC3B by SIV Vif. Oncotarget. PMID 26544511 DOI: 10.18632/oncotarget.5483  0.92
2015 Shlyakhtenko LS, Dutta S, Banga J, Li M, Harris RS, Lyubchenko YL. APOBEC3G Interacts with ssDNA by Two Modes: AFM Studies. Scientific Reports. 5: 15648. PMID 26503602 DOI: 10.1038/srep15648  0.92
2015 Leonard B, McCann JL, Starrett GJ, Kosyakovsky L, Luengas EM, Molan AM, Burns MB, McDougle RM, Parker PJ, Brown WL, Harris RS. The PKC/NF-κB Signaling Pathway Induces APOBEC3B Expression in Multiple Human Cancers. Cancer Research. 75: 4538-47. PMID 26420215 DOI: 10.1158/0008-5472.CAN-15-2171-T  0.92
2015 Shi K, Carpenter MA, Kurahashi K, Harris RS, Aihara H. Crystal Structure of the DNA Deaminase APOBEC3B Catalytic Domain. The Journal of Biological Chemistry. PMID 26416889 DOI: 10.1074/jbc.M115.679951  0.92
2015 Olson ME, Abate-Pella D, Perkins AL, Li M, Carpenter MA, Rathore A, Harris RS, Harki DA. Oxidative Reactivities of 2-Furylquinolines: Ubiquitous Scaffolds in Common High-Throughput Screening Libraries. Journal of Medicinal Chemistry. PMID 26358009 DOI: 10.1021/acs.jmedchem.5b00930  0.92
2015 Kouno T, Luengas EM, Shigematsu M, Shandilya SM, Zhang J, Chen L, Hara M, Schiffer CA, Harris RS, Matsuo H. Structure of the Vif-binding domain of the antiviral enzyme APOBEC3G. Nature Structural & Molecular Biology. 22: 485-91. PMID 25984970 DOI: 10.1038/nsmb.3033  0.92
2015 Kane JR, Stanley DJ, Hultquist JF, Johnson JR, Mietrach N, Binning JM, Jónsson SR, Barelier S, Newton BW, Johnson TL, Franks-Skiba KE, Li M, Brown WL, Gunnarsson HI, Adalbjornsdóttir A, ... ... Harris RS, et al. Lineage-Specific Viral Hijacking of Non-canonical E3 Ubiquitin Ligase Cofactors in the Evolution of Vif Anti-APOBEC3 Activity. Cell Reports. 11: 1236-50. PMID 25981045 DOI: 10.1016/j.celrep.2015.04.038  0.92
2015 Harris RS, Perrino FW, Shaban NM. The multidimensional nature of antiviral innate immunity. Cell Host & Microbe. 17: 423-5. PMID 25856751 DOI: 10.1016/j.chom.2015.03.011  0.92
2015 Harris RS, Dudley JP. APOBECs and virus restriction. Virology. 479: 131-45. PMID 25818029 DOI: 10.1016/j.virol.2015.03.012  0.92
2015 Burns MB, Leonard B, Harris RS. APOBEC3B: pathological consequences of an innate immune DNA mutator. Biomedical Journal. 38: 102-10. PMID 25566802 DOI: 10.4103/2319-4170.148904  0.92
2015 Yoshikawa R, Takeuchi JS, Yamada E, Nakano Y, Ren F, Tanaka H, Münk C, Harris RS, Miyazawa T, Koyanagi Y, Sato K. Vif determines the requirement for CBF-β in APOBEC3 degradation. The Journal of General Virology. 96: 887-92. PMID 25516542 DOI: 10.1099/jgv.0.000027  0.92
2014 Vieira VC, Leonard B, White EA, Starrett GJ, Temiz NA, Lorenz LD, Lee D, Soares MA, Lambert PF, Howley PM, Harris RS. Human papillomavirus E6 triggers upregulation of the antiviral and cancer genomic DNA deaminase APOBEC3B. Mbio. 5. PMID 25538195 DOI: 10.1128/mBio.02234-14  0.92
2014 Refsland EW, Hultquist JF, Luengas EM, Ikeda T, Shaban NM, Law EK, Brown WL, Reilly C, Emerman M, Harris RS. Natural polymorphisms in human APOBEC3H and HIV-1 Vif combine in primary T lymphocytes to affect viral G-to-A mutation levels and infectivity. Plos Genetics. 10: e1004761. PMID 25411794 DOI: 10.1371/journal.pgen.1004761  0.92
2014 Land AM, Shaban NM, Evans L, Hultquist JF, Albin JS, Harris RS. APOBEC3F determinants of HIV-1 Vif sensitivity. Journal of Virology. 88: 12923-7. PMID 25142588 DOI: 10.1128/JVI.02362-14  0.92
2014 Sieuwerts AM, Willis S, Burns MB, Look MP, Meijer-Van Gelder ME, Schlicker A, Heideman MR, Jacobs H, Wessels L, Leyland-Jones B, Gray KP, Foekens JA, Harris RS, Martens JW. Elevated APOBEC3B correlates with poor outcomes for estrogen-receptor-positive breast cancers. Hormones & Cancer. 5: 405-13. PMID 25123150 DOI: 10.1007/s12672-014-0196-8  0.92
2014 Matsui M, Shindo K, Izumi T, Io K, Shinohara M, Komano J, Kobayashi M, Kadowaki N, Harris RS, Takaori-Kondo A. Small molecules that inhibit Vif-induced degradation of APOBEC3G. Virology Journal. 11: 122. PMID 24986077 DOI: 10.1186/1743-422X-11-122  0.92
2014 Albin JS, Brown WL, Harris RS. Catalytic activity of APOBEC3F is required for efficient restriction of Vif-deficient human immunodeficiency virus. Virology. 450: 49-54. PMID 24503066 DOI: 10.1016/j.virol.2013.11.041  0.92
2014 Matsui Y, Shindo K, Nagata K, Io K, Tada K, Iwai F, Kobayashi M, Kadowaki N, Harris RS, Takaori-Kondo A. Defining HIV-1 Vif residues that interact with CBFβ by site-directed mutagenesis. Virology. 449: 82-7. PMID 24418540 DOI: 10.1016/j.virol.2013.11.004  0.64
2014 Li J, Chen Y, Li M, Carpenter MA, McDougle RM, Luengas EM, Macdonald PJ, Harris RS, Mueller JD. APOBEC3 multimerization correlates with HIV-1 packaging and restriction activity in living cells. Journal of Molecular Biology. 426: 1296-307. PMID 24361275 DOI: 10.1016/j.jmb.2013.12.014  0.92
2013 Shee C, Cox BD, Gu F, Luengas EM, Joshi MC, Chiu LY, Magnan D, Halliday JA, Frisch RL, Gibson JL, Nehring RB, Do HG, Hernandez M, Li L, Herman C, ... ... Harris RS, et al. Engineered proteins detect spontaneous DNA breakage in human and bacterial cells. Elife. 2: e01222. PMID 24171103 DOI: 10.7554/eLife.01222  0.92
2013 Leonard B, Hart SN, Burns MB, Carpenter MA, Temiz NA, Rathore A, Vogel RI, Nikas JB, Law EK, Brown WL, Li Y, Zhang Y, Maurer MJ, Oberg AL, Cunningham JM, ... ... Harris RS, et al. APOBEC3B upregulation and genomic mutation patterns in serous ovarian carcinoma. Cancer Research. 73: 7222-31. PMID 24154874 DOI: 10.1158/0008-5472.CAN-13-1753  0.92
2013 Rathore A, Carpenter MA, Demir Ö, Ikeda T, Li M, Shaban NM, Law EK, Anokhin D, Brown WL, Amaro RE, Harris RS. The local dinucleotide preference of APOBEC3G can be altered from 5'-CC to 5'-TC by a single amino acid substitution. Journal of Molecular Biology. 425: 4442-54. PMID 23938202 DOI: 10.1016/j.jmb.2013.07.040  0.92
2013 Ali S, Karki N, Bhattacharya C, Zhu R, MacDuff DA, Stenglein MD, Schumacher AJ, Demorest ZL, Harris RS, Matin A, Aggarwal S. APOBEC3 inhibits DEAD-END function to regulate microRNA activity. Bmc Molecular Biology. 14: 16. PMID 23890083 DOI: 10.1186/1471-2199-14-16  0.92
2013 Burns MB, Temiz NA, Harris RS. Evidence for APOBEC3B mutagenesis in multiple human cancers. Nature Genetics. 45: 977-83. PMID 23852168 DOI: 10.1038/ng.2701  0.92
2013 Refsland EW, Harris RS. The APOBEC3 family of retroelement restriction factors. Current Topics in Microbiology and Immunology. 371: 1-27. PMID 23686230 DOI: 10.1007/978-3-642-37765-5_1  0.92
2013 Bohn MF, Shandilya SM, Albin JS, Kouno T, Anderson BD, McDougle RM, Carpenter MA, Rathore A, Evans L, Davis AN, Zhang J, Lu Y, Somasundaran M, Matsuo H, Harris RS, et al. Crystal structure of the DNA cytosine deaminase APOBEC3F: the catalytically active and HIV-1 Vif-binding domain. Structure (London, England : 1993). 21: 1042-50. PMID 23685212 DOI: 10.1016/j.str.2013.04.010  0.92
2013 Land AM, Law EK, Carpenter MA, Lackey L, Brown WL, Harris RS. Endogenous APOBEC3A DNA cytosine deaminase is cytoplasmic and nongenotoxic. The Journal of Biological Chemistry. 288: 17253-60. PMID 23640892 DOI: 10.1074/jbc.M113.458661  0.92
2013 Harjes S, Solomon WC, Li M, Chen KM, Harjes E, Harris RS, Matsuo H. Impact of H216 on the DNA binding and catalytic activities of the HIV restriction factor APOBEC3G. Journal of Virology. 87: 7008-14. PMID 23596292 DOI: 10.1128/JVI.03173-12  0.36
2013 McDougle RM, Hultquist JF, Stabell AC, Sawyer SL, Harris RS. D316 is critical for the enzymatic activity and HIV-1 restriction potential of human and rhesus APOBEC3B. Virology. 441: 31-9. PMID 23542011 DOI: 10.1016/j.virol.2013.03.003  0.92
2013 Burns MB, Lackey L, Carpenter MA, Rathore A, Land AM, Leonard B, Refsland EW, Kotandeniya D, Tretyakova N, Nikas JB, Yee D, Temiz NA, Donohue DE, McDougle RM, Brown WL, ... ... Harris RS, et al. APOBEC3B is an enzymatic source of mutation in breast cancer. Nature. 494: 366-70. PMID 23389445 DOI: 10.1038/nature11881  0.92
2013 Lackey L, Law EK, Brown WL, Harris RS. Subcellular localization of the APOBEC3 proteins during mitosis and implications for genomic DNA deamination. Cell Cycle (Georgetown, Tex.). 12: 762-72. PMID 23388464 DOI: 10.4161/cc.23713  0.92
2013 Albin JS, Anderson JS, Johnson JR, Harjes E, Matsuo H, Krogan NJ, Harris RS. Dispersed sites of HIV Vif-dependent polyubiquitination in the DNA deaminase APOBEC3F. Journal of Molecular Biology. 425: 1172-82. PMID 23318957 DOI: 10.1016/j.jmb.2013.01.010  0.92
2013 Olson ME, Li M, Harris RS, Harki DA. Small-molecule APOBEC3G DNA cytosine deaminase inhibitors based on a 4-amino-1,2,4-triazole-3-thiol scaffold. Chemmedchem. 8: 112-7. PMID 23180603 DOI: 10.1002/cmdc.201200411  0.92
2012 Shindo K, Li M, Gross PJ, Brown WL, Harjes E, Lu Y, Matsuo H, Harris RS. A Comparison of Two Single-Stranded DNA Binding Models by Mutational Analysis of APOBEC3G. Biology. 1: 260-76. PMID 24832226 DOI: 10.3390/biology1020260  0.92
2012 Stanley DJ, Bartholomeeusen K, Crosby DC, Kim DY, Kwon E, Yen L, Cartozo NC, Li M, Jäger S, Mason-Herr J, Hayashi F, Yokoyama S, Krogan NJ, Harris RS, Peterlin BM, et al. Inhibition of a NEDD8 Cascade Restores Restriction of HIV by APOBEC3G. Plos Pathogens. 8: e1003085. PMID 23300442 DOI: 10.1371/journal.ppat.1003085  0.92
2012 Harris RS, Hultquist JF, Evans DT. The restriction factors of human immunodeficiency virus. The Journal of Biological Chemistry. 287: 40875-83. PMID 23043100 DOI: 10.1074/jbc.R112.416925  0.92
2012 Solyom S, Ewing AD, Rahrmann EP, Doucet T, Nelson HH, Burns MB, Harris RS, Sigmon DF, Casella A, Erlanger B, Wheelan S, Upton KR, Shukla R, Faulkner GJ, Largaespada DA, et al. Extensive somatic L1 retrotransposition in colorectal tumors. Genome Research. 22: 2328-38. PMID 22968929 DOI: 10.1101/gr.145235.112  0.92
2012 Carpenter MA, Li M, Rathore A, Lackey L, Law EK, Land AM, Leonard B, Shandilya SM, Bohn MF, Schiffer CA, Brown WL, Harris RS. Methylcytosine and normal cytosine deamination by the foreign DNA restriction enzyme APOBEC3A. The Journal of Biological Chemistry. 287: 34801-8. PMID 22896697 DOI: 10.1074/jbc.M112.385161  0.92
2012 Refsland EW, Hultquist JF, Harris RS. Endogenous origins of HIV-1 G-to-A hypermutation and restriction in the nonpermissive T cell line CEM2n. Plos Pathogens. 8: e1002800. PMID 22807680 DOI: 10.1371/journal.ppat.1002800  0.92
2012 Hultquist JF, McDougle RM, Anderson BD, Harris RS. HIV type 1 viral infectivity factor and the RUNX transcription factors interact with core binding factor β on genetically distinct surfaces. Aids Research and Human Retroviruses. 28: 1543-51. PMID 22725134 DOI: 10.1089/AID.2012.0142  0.92
2012 Nowarski R, Wilner OI, Cheshin O, Shahar OD, Kenig E, Baraz L, Britan-Rosich E, Nagler A, Harris RS, Goldberg M, Willner I, Kotler M. APOBEC3G enhances lymphoma cell radioresistance by promoting cytidine deaminase-dependent DNA repair. Blood. 120: 366-75. PMID 22645179 DOI: 10.1182/blood-2012-01-402123  0.92
2012 Lackey L, Demorest ZL, Land AM, Hultquist JF, Brown WL, Harris RS. APOBEC3B and AID have similar nuclear import mechanisms. Journal of Molecular Biology. 419: 301-14. PMID 22446380 DOI: 10.1016/j.jmb.2012.03.011  0.92
2012 Hultquist JF, Binka M, LaRue RS, Simon V, Harris RS. Vif proteins of human and simian immunodeficiency viruses require cellular CBFβ to degrade APOBEC3 restriction factors. Journal of Virology. 86: 2874-7. PMID 22205746 DOI: 10.1128/JVI.06950-11  0.92
2012 Jäger S, Kim DY, Hultquist JF, Shindo K, LaRue RS, Kwon E, Li M, Anderson BD, Yen L, Stanley D, Mahon C, Kane J, Franks-Skiba K, Cimermancic P, Burlingame A, ... ... Harris RS, et al. Vif hijacks CBF-β to degrade APOBEC3G and promote HIV-1 infection. Nature. 481: 371-5. PMID 22190037 DOI: 10.1038/nature10693  0.92
2012 Li M, Shandilya SM, Carpenter MA, Rathore A, Brown WL, Perkins AL, Harki DA, Solberg J, Hook DJ, Pandey KK, Parniak MA, Johnson JR, Krogan NJ, Somasundaran M, Ali A, ... ... Harris RS, et al. First-in-class small molecule inhibitors of the single-strand DNA cytosine deaminase APOBEC3G. Acs Chemical Biology. 7: 506-17. PMID 22181350 DOI: 10.1021/cb200440y  0.92
2011 Hultquist JF, Lengyel JA, Refsland EW, LaRue RS, Lackey L, Brown WL, Harris RS. Human and rhesus APOBEC3D, APOBEC3F, APOBEC3G, and APOBEC3H demonstrate a conserved capacity to restrict Vif-deficient HIV-1. Journal of Virology. 85: 11220-34. PMID 21835787 DOI: 10.1128/JVI.05238-11  0.92
2011 Demorest ZL, Li M, Harris RS. Phosphorylation directly regulates the intrinsic DNA cytidine deaminase activity of activation-induced deaminase and APOBEC3G protein. The Journal of Biological Chemistry. 286: 26568-75. PMID 21659520 DOI: 10.1074/jbc.M111.235721  0.92
2011 Shlyakhtenko LS, Lushnikov AY, Li M, Lackey L, Harris RS, Lyubchenko YL. Atomic force microscopy studies provide direct evidence for dimerization of the HIV restriction factor APOBEC3G. The Journal of Biological Chemistry. 286: 3387-95. PMID 21123176 DOI: 10.1074/jbc.M110.195685  0.92
2010 Albin JS, LaRue RS, Weaver JA, Brown WL, Shindo K, Harjes E, Matsuo H, Harris RS. A single amino acid in human APOBEC3F alters susceptibility to HIV-1 Vif. The Journal of Biological Chemistry. 285: 40785-92. PMID 20971849 DOI: 10.1074/jbc.M110.173161  0.92
2010 Offer SM, Pan-Hammarström Q, Hammarström L, Harris RS. Unique DNA repair gene variations and potential associations with the primary antibody deficiency syndromes IgAD and CVID. Plos One. 5: e12260. PMID 20805886 DOI: 10.1371/journal.pone.0012260  0.92
2010 Albin JS, Haché G, Hultquist JF, Brown WL, Harris RS. Long-term restriction by APOBEC3F selects human immunodeficiency virus type 1 variants with restored Vif function. Journal of Virology. 84: 10209-19. PMID 20686027 DOI: 10.1128/JVI.00632-10  0.92
2010 Demorest ZL, MacDuff DA, Brown WL, Morham SG, Parise LV, Harris RS. The interaction between AID and CIB1 is nonessential for antibody gene diversification by gene conversion or class switch recombination. Plos One. 5: e11660. PMID 20652029 DOI: 10.1371/journal.pone.0011660  0.92
2010 Hastings PJ, Hersh MN, Thornton PC, Fonville NC, Slack A, Frisch RL, Ray MP, Harris RS, Leal SM, Rosenberg SM. Competition of Escherichia coli DNA polymerases I, II and III with DNA Pol IV in stressed cells. Plos One. 5: e10862. PMID 20523737 DOI: 10.1371/journal.pone.0010862  0.92
2010 Larue RS, Lengyel J, Jónsson SR, Andrésdóttir V, Harris RS. Lentiviral Vif degrades the APOBEC3Z3/APOBEC3H protein of its mammalian host and is capable of cross-species activity. Journal of Virology. 84: 8193-201. PMID 20519393 DOI: 10.1128/JVI.00685-10  0.92
2010 Sadler HA, Stenglein MD, Harris RS, Mansky LM. APOBEC3G contributes to HIV-1 variation through sublethal mutagenesis. Journal of Virology. 84: 7396-404. PMID 20463080 DOI: 10.1128/JVI.00056-10  0.92
2010 Refsland EW, Stenglein MD, Shindo K, Albin JS, Brown WL, Harris RS. Quantitative profiling of the full APOBEC3 mRNA repertoire in lymphocytes and tissues: implications for HIV-1 restriction. Nucleic Acids Research. 38: 4274-84. PMID 20308164 DOI: 10.1093/nar/gkq174  0.92
2010 Shandilya SM, Nalam MN, Nalivaika EA, Gross PJ, Valesano JC, Shindo K, Li M, Munson M, Royer WE, Harjes E, Kono T, Matsuo H, Harris RS, Somasundaran M, Schiffer CA. Crystal structure of the APOBEC3G catalytic domain reveals potential oligomerization interfaces. Structure (London, England : 1993). 18: 28-38. PMID 20152150 DOI: 10.1016/j.str.2009.10.016  0.92
2010 Albin JS, Harris RS. Interactions of host APOBEC3 restriction factors with HIV-1 in vivo: implications for therapeutics. Expert Reviews in Molecular Medicine. 12: e4. PMID 20096141 DOI: 10.1017/S1462399409001343  0.92
2010 Stenglein MD, Burns MB, Li M, Lengyel J, Harris RS. APOBEC3 proteins mediate the clearance of foreign DNA from human cells. Nature Structural & Molecular Biology. 17: 222-9. PMID 20062055 DOI: 10.1038/nsmb.1744  0.92
2009 Hultquist JF, Harris RS. Leveraging APOBEC3 proteins to alter the HIV mutation rate and combat AIDS. Future Virology. 4: 605. PMID 20174454 DOI: 10.2217/fvl.09.59  0.92
2009 Harjes E, Gross PJ, Chen KM, Lu Y, Shindo K, Nowarski R, Gross JD, Kotler M, Harris RS, Matsuo H. An extended structure of the APOBEC3G catalytic domain suggests a unique holoenzyme model. Journal of Molecular Biology. 389: 819-32. PMID 19389408 DOI: 10.1016/j.jmb.2009.04.031  0.64
2009 MacDuff DA, Demorest ZL, Harris RS. AID can restrict L1 retrotransposition suggesting a dual role in innate and adaptive immunity. Nucleic Acids Research. 37: 1854-67. PMID 19188259 DOI: 10.1093/nar/gkp030  0.92
2009 LaRue RS, Andrésdóttir V, Blanchard Y, Conticello SG, Derse D, Emerman M, Greene WC, Jónsson SR, Landau NR, Löchelt M, Malik HS, Malim MH, Münk C, O'Brien SJ, Pathak VK, ... ... Harris RS, et al. Guidelines for naming nonprimate APOBEC3 genes and proteins. Journal of Virology. 83: 494-7. PMID 18987154 DOI: 10.1128/JVI.01976-08  0.92
2008 LaRue RS, Jónsson SR, Silverstein KA, Lajoie M, Bertrand D, El-Mabrouk N, Hötzel I, Andrésdóttir V, Smith TP, Harris RS. The artiodactyl APOBEC3 innate immune repertoire shows evidence for a multi-functional domain organization that existed in the ancestor of placental mammals. Bmc Molecular Biology. 9: 104. PMID 19017397 DOI: 10.1186/1471-2199-9-104  0.92
2008 Stenglein MD, Matsuo H, Harris RS. Two regions within the amino-terminal half of APOBEC3G cooperate to determine cytoplasmic localization. Journal of Virology. 82: 9591-9. PMID 18667511 DOI: 10.1128/JVI.02471-07  0.92
2008 DeHart JL, Bosque A, Harris RS, Planelles V. Human immunodeficiency virus type 1 Vif induces cell cycle delay via recruitment of the same E3 ubiquitin ligase complex that targets APOBEC3 proteins for degradation. Journal of Virology. 82: 9265-72. PMID 18596088 DOI: 10.1128/JVI.00377-08  0.92
2008 Haché G, Shindo K, Albin JS, Harris RS. Evolution of HIV-1 isolates that use a novel Vif-independent mechanism to resist restriction by human APOBEC3G. Current Biology : Cb. 18: 819-24. PMID 18501607 DOI: 10.1016/j.cub.2008.04.073  0.92
2008 Chen KM, Harjes E, Gross PJ, Fahmy A, Lu Y, Shindo K, Harris RS, Matsuo H. Structure of the DNA deaminase domain of the HIV-1 restriction factor APOBEC3G. Nature. 452: 116-9. PMID 18288108 DOI: 10.1038/nature06638  0.64
2008 Schumacher AJ, Haché G, Macduff DA, Brown WL, Harris RS. The DNA deaminase activity of human APOBEC3G is required for Ty1, MusD, and human immunodeficiency virus type 1 restriction. Journal of Virology. 82: 2652-60. PMID 18184715 DOI: 10.1128/JVI.02391-07  0.92
2007 Chen KM, Martemyanova N, Lu Y, Shindo K, Matsuo H, Harris RS. Extensive mutagenesis experiments corroborate a structural model for the DNA deaminase domain of APOBEC3G. Febs Letters. 581: 4761-6. PMID 17869248 DOI: 10.1016/j.febslet.2007.08.076  0.64
2007 Jónsson SR, LaRue RS, Stenglein MD, Fahrenkrug SC, Andrésdóttir V, Harris RS. The restriction of zoonotic PERV transmission by human APOBEC3G. Plos One. 2: e893. PMID 17849022 DOI: 10.1371/journal.pone.0000893  0.92
2007 Mbisa JL, Barr R, Thomas JA, Vandegraaff N, Dorweiler IJ, Svarovskaia ES, Brown WL, Mansky LM, Gorelick RJ, Harris RS, Engelman A, Pathak VK. Human immunodeficiency virus type 1 cDNAs produced in the presence of APOBEC3G exhibit defects in plus-strand DNA transfer and integration. Journal of Virology. 81: 7099-110. PMID 17428871 DOI: 10.1128/JVI.00272-07  0.68
2007 Sekine H, Ferreira RC, Pan-Hammarström Q, Graham RR, Ziemba B, de Vries SS, Liu J, Hippen K, Koeuth T, Ortmann W, Iwahori A, Elliott MK, Offer S, Skon C, Du L, ... ... Harris RS, et al. Role for Msh5 in the regulation of Ig class switch recombination. Proceedings of the National Academy of Sciences of the United States of America. 104: 7193-8. PMID 17409188 DOI: 10.1073/pnas.0700815104  0.92
2007 Cook AJ, Raftery JM, Lau KK, Jessup A, Harris RS, Takeda S, Jolly CJ. DNA-dependent protein kinase inhibits AID-induced antibody gene conversion. Plos Biology. 5: e80. PMID 17355182 DOI: 10.1371/journal.pbio.0050080  0.92
2006 Haché G, Mansky LM, Harris RS. Human APOBEC3 proteins, retrovirus restriction, and HIV drug resistance. Aids Reviews. 8: 148-57. PMID 17078485  0.92
2006 Jónsson SR, Haché G, Stenglein MD, Fahrenkrug SC, Andrésdóttir V, Harris RS. Evolutionarily conserved and non-conserved retrovirus restriction activities of artiodactyl APOBEC3F proteins. Nucleic Acids Research. 34: 5683-94. PMID 17038330 DOI: 10.1093/nar/gkl721  0.92
2006 Harris RS, Matsuo H. Dancin' deaminase. Nature Structural & Molecular Biology. 13: 380-1. PMID 16738602 DOI: 10.1038/nsmb0506-380  0.36
2006 Stenglein MD, Harris RS. APOBEC3B and APOBEC3F inhibit L1 retrotransposition by a DNA deamination-independent mechanism. The Journal of Biological Chemistry. 281: 16837-41. PMID 16648136 DOI: 10.1074/jbc.M602367200  0.92
2006 Macduff DA, Harris RS. Directed DNA deamination by AID/APOBEC3 in immunity. Current Biology : Cb. 16: R186-9. PMID 16546065 DOI: 10.1016/j.cub.2006.02.035  0.92
2006 MacDuff DA, Neuberger MS, Harris RS. MDM2 can interact with the C-terminus of AID but it is inessential for antibody diversification in DT40 B cells. Molecular Immunology. 43: 1099-108. PMID 16122802 DOI: 10.1016/j.molimm.2005.07.024  0.92
2005 Schumacher AJ, Nissley DV, Harris RS. APOBEC3G hypermutates genomic DNA and inhibits Ty1 retrotransposition in yeast. Proceedings of the National Academy of Sciences of the United States of America. 102: 9854-9. PMID 16000409 DOI: 10.1073/pnas.0501694102  0.92
2005 Haché G, Liddament MT, Harris RS. The retroviral hypermutation specificity of APOBEC3F and APOBEC3G is governed by the C-terminal DNA cytosine deaminase domain. The Journal of Biological Chemistry. 280: 10920-4. PMID 15647250 DOI: 10.1074/jbc.M500382200  0.4
2004 Harris RS, Liddament MT. Retroviral restriction by APOBEC proteins. Nature Reviews. Immunology. 4: 868-77. PMID 15516966 DOI: 10.1038/nri1489  0.4
2004 Liddament MT, Brown WL, Schumacher AJ, Harris RS. APOBEC3F properties and hypermutation preferences indicate activity against HIV-1 in vivo. Current Biology : Cb. 14: 1385-91. PMID 15296757 DOI: 10.1016/j.cub.2004.06.050  0.92
2003 Harris RS, Sheehy AM, Craig HM, Malim MH, Neuberger MS. DNA deamination: not just a trigger for antibody diversification but also a mechanism for defense against retroviruses. Nature Immunology. 4: 641-3. PMID 12830140 DOI: 10.1038/ni0703-641  0.92
2003 Neuberger MS, Harris RS, Di Noia J, Petersen-Mahrt SK. Immunity through DNA deamination. Trends in Biochemical Sciences. 28: 305-12. PMID 12826402 DOI: 10.1016/S0968-0004(03)00111-7  0.92
2003 Harris RS, Bishop KN, Sheehy AM, Craig HM, Petersen-Mahrt SK, Watt IN, Neuberger MS, Malim MH. DNA deamination mediates innate immunity to retroviral infection. Cell. 113: 803-9. PMID 12809610 DOI: 10.1016/S0092-8674(03)00423-9  0.92
Show low-probability matches.