Karla Kirkegaard - Publications

Affiliations: 
Stanford University, Palo Alto, CA 
Area:
Virology Biology, Microbiology Biology

93 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Andino R, Kirkegaard K, Macadam A, Racaniello VR, Rosenfeld AB. The Picornaviridae Family: Knowledge Gaps, Animal Models, Countermeasures, and Prototype Pathogens. The Journal of Infectious Diseases. 228: S427-S445. PMID 37849401 DOI: 10.1093/infdis/jiac426  0.73
2020 Selzer L, Su Z, Pintilie GD, Chiu W, Kirkegaard K. Full-length three-dimensional structure of the influenza A virus M1 protein and its organization into a matrix layer. Plos Biology. 18: e3000827. PMID 32997652 DOI: 10.1371/journal.pbio.3000827  0.77
2020 Jones ST, Cagno V, Janeček M, Ortiz D, Gasilova N, Piret J, Gasbarri M, Constant DA, Han Y, Vuković L, Král P, Kaiser L, Huang S, Constant S, Kirkegaard K, et al. Modified cyclodextrins as broad-spectrum antivirals. Science Advances. 6: eaax9318. PMID 32064341 DOI: 10.1126/Sciadv.Aax9318  0.396
2019 Ooi YS, Majzoub K, Flynn RA, Mata MA, Diep J, Li JK, van Buuren N, Rumachik N, Johnson AG, Puschnik AS, Marceau CD, Mlera L, Grabowski JM, Kirkegaard K, Bloom ME, et al. An RNA-centric dissection of host complexes controlling flavivirus infection. Nature Microbiology. PMID 31384002 DOI: 10.1038/S41564-019-0518-2  0.533
2019 Abernathy E, Mateo R, Majzoub K, van Buuren N, Bird SW, Carette JE, Kirkegaard K. Differential and convergent utilization of autophagy components by positive-strand RNA viruses. Plos Biology. 17: e2006926. PMID 30608919 DOI: 10.1371/Journal.Pbio.2006926  0.493
2019 Rankin CR, Buuren NV, Kirkegaard K, Rowe L, Pothoulakis C, Padua DM. P151 The Long Non-Coding Rna, Ifng-As1/Nest, Is Associated With Ibd And Drives A Pro-Inflammatory Signaling Cascade Gastroenterology. 156. DOI: 10.1016/S0016-5085(19)36951-3  0.33
2018 van Buuren N, Kirkegaard K. Detection and Differentiation of Multiple Viral RNAs Using Branched DNA FISH Coupled to Confocal Microscopy and Flow Cytometry. Bio-Protocol. 8. PMID 30505886 DOI: 10.21769/BioProtoc.3058  0.341
2018 Constant DA, Mateo R, Nagamine CM, Kirkegaard K. Targeting intramolecular proteinase NS2B/3 cleavages for -dominant inhibition of dengue virus. Proceedings of the National Academy of Sciences of the United States of America. PMID 30228122 DOI: 10.1073/Pnas.1805195115  0.476
2018 van Buuren N, Tellinghuisen TL, Richardson CD, Kirkegaard K. Transmission genetics of drug-resistant hepatitis C virus. Elife. 7. PMID 29589830 DOI: 10.7554/Elife.32579  0.368
2018 Delorme-Axford E, Abernathy E, Lennemann NJ, Bernard A, Ariosa A, Coyne CB, Kirkegaard K, Klionsky DJ. The Exoribonuclease Xrn1 Is a Post-Transcriptional Negative Regulator of Autophagy. Autophagy. 1-47. PMID 29465287 DOI: 10.1080/15548627.2018.1441648  0.31
2018 Padua DM, Rankin CR, van Buuren N, Kirkegaard K. Su1055 - Gene Expression Profiling Identifies Ifng-As1/Nest as a Long Non-Coding RNA Associated with IBD Gastroenterology. 154: S-469. DOI: 10.1016/S0016-5085(18)31811-0  0.345
2018 Selzer L, Moshiri J, Kirkegaard K. Investigating Ph-Induced Changes of the Influenza a Virus Matrix Layer Biophysical Journal. 114: 372a-373a. DOI: 10.1016/J.Bpj.2017.11.2064  0.749
2017 Kirkegaard K. Unconventional secretion of hepatitis A virus. Proceedings of the National Academy of Sciences of the United States of America. PMID 28607085 DOI: 10.1073/Pnas.1707142114  0.474
2016 Kirkegaard K, van Buuren NJ, Mateo R. My Cousin, My Enemy: quasispecies suppression of drug resistance. Current Opinion in Virology. 20: 106-111. PMID 27764731 DOI: 10.1016/J.Coviro.2016.09.011  0.302
2016 Klionsky DJ, Abdelmohsen K, Abe A, Abedin J, Abeliovich H, Arozena AA, Adachi H, Adams CM, Adams PD, Adeli K, Adhihetty PJ, Adler SG, Agam G, Agarwal R, Aghi MK, ... ... Kirkegaard K, et al. Erratum to: Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (Autophagy, 12, 1, 1-222, 10.1080/15548627.2015.1100356 Autophagy. 12: 443-443. PMID 26902590 DOI: 10.1080/15548627.2016.1147886  0.491
2016 Neufeldt CJ, Joyce MA, Van Buuren N, Levin A, Kirkegaard K, Gale M, Tyrrell DL, Wozniak RW. The Hepatitis C Virus-Induced Membranous Web and Associated Nuclear Transport Machinery Limit Access of Pattern Recognition Receptors to Viral Replication Sites. Plos Pathogens. 12: e1005428. PMID 26863439 DOI: 10.1371/Journal.Ppat.1005428  0.489
2016 Klionsky DJ, Abdelmohsen K, Abe A, Abedin MJ, Abeliovich H, Acevedo Arozena A, Adachi H, Adams CM, Adams PD, Adeli K, Adhihetty PJ, Adler SG, Agam G, Agarwal R, Aghi MK, ... ... Kirkegaard K, et al. Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). Autophagy. 12: 1-222. PMID 26799652 DOI: 10.1080/15548627.2015.1100356  0.563
2015 Mateo R, Nagamine CM, Kirkegaard K. Suppression of Drug Resistance in Dengue Virus. Mbio. 6: e01960-15. PMID 26670386 DOI: 10.1128/Mbio.01960-15  0.41
2015 Bird SW, Kirkegaard K. Escape of non-enveloped virus from intact cells. Virology. 479: 444-9. PMID 25890822 DOI: 10.1016/J.Virol.2015.03.044  0.43
2015 Bird SW, Kirkegaard K. Nonlytic spread of naked viruses. Autophagy. 11: 430-1. PMID 25680079 DOI: 10.4161/15548627.2014.994372  0.416
2014 Bird SW, Kirkegaard K, Agbandje-McKenna M, Freed EO. The ins and outs of viral infection: keystone meeting review. Viruses. 6: 3652-62. PMID 25256395 DOI: 10.3390/V6093652  0.417
2014 Bird SW, Maynard ND, Covert MW, Kirkegaard K. Nonlytic viral spread enhanced by autophagy components. Proceedings of the National Academy of Sciences of the United States of America. 111: 13081-6. PMID 25157142 DOI: 10.1073/Pnas.1401437111  0.412
2013 Wang J, Ptacek JB, Kirkegaard K, Bullitt E. Double-membraned liposomes sculpted by poliovirus 3AB protein. The Journal of Biological Chemistry. 288: 27287-98. PMID 23908350 DOI: 10.1074/Jbc.M113.498899  0.423
2013 Gomez JA, Wapinski OL, Yang YW, Bureau JF, Gopinath S, Monack DM, Chang HY, Brahic M, Kirkegaard K. The NeST long ncRNA controls microbial susceptibility and epigenetic activation of the interferon-γ locus. Cell. 152: 743-54. PMID 23415224 DOI: 10.1016/J.Cell.2013.01.015  0.534
2013 Mateo R, Nagamine CM, Spagnolo J, Méndez E, Rahe M, Gale M, Yuan J, Kirkegaard K. Inhibition of cellular autophagy deranges dengue virion maturation. Journal of Virology. 87: 1312-21. PMID 23175363 DOI: 10.1128/Jvi.02177-12  0.485
2013 Kirkegaard K. Sculpting and Subversion of Membranes during Poliovirus in Assembly of RNA Replication Complexes and in Egress Biophysical Journal. 104: 12a. DOI: 10.1016/J.Bpj.2012.11.094  0.516
2012 Maynard ND, Macklin DN, Kirkegaard K, Covert MW. Competing pathways control host resistance to virus via tRNA modification and programmed ribosomal frameshifting. Molecular Systems Biology. 8: 567. PMID 22294093 DOI: 10.1038/Msb.2011.101  0.395
2012 Wang J, Bullitt E, Kirkegaard K. Surface for catalysis by poliovirus RNA dependent RNA polymerase Microscopy and Microanalysis. 18: 68-69. DOI: 10.1017/S143192761200219X  0.454
2011 Tellez AB, Wang J, Tanner EJ, Spagnolo JF, Kirkegaard K, Bullitt E. Interstitial contacts in an RNA-dependent RNA polymerase lattice. Journal of Molecular Biology. 412: 737-50. PMID 21839092 DOI: 10.1016/J.Jmb.2011.07.053  0.815
2011 Tellez A, Wang J, Rossignol E, Ptacek J, Kirkegaard K, Bullitt E. The Role of Oligomerization in Poliovirus Polymerase Function Microscopy and Microanalysis. 17: 130-131. DOI: 10.1017/S1431927611001528  0.744
2010 Parameswaran P, Sklan E, Wilkins C, Burgon T, Samuel MA, Lu R, Ansel KM, Heissmeyer V, Einav S, Jackson W, Doukas T, Paranjape S, Polacek C, dos Santos FB, Jalili R, ... ... Kirkegaard K, et al. Six RNA viruses and forty-one hosts: viral small RNAs and modulation of small RNA repertoires in vertebrate and invertebrate systems. Plos Pathogens. 6: e1000764. PMID 20169186 DOI: 10.1371/Journal.Ppat.1000764  0.824
2010 Spagnolo JF, Rossignol E, Bullitt E, Kirkegaard K. Enzymatic and nonenzymatic functions of viral RNA-dependent RNA polymerases within oligomeric arrays. Rna (New York, N.Y.). 16: 382-93. PMID 20051491 DOI: 10.1261/Rna.1955410  0.57
2009 Kirkegaard K. Subversion of the cellular autophagy pathway by viruses. Current Topics in Microbiology and Immunology. 335: 323-33. PMID 19802573 DOI: 10.1007/978-3-642-00302-8_16  0.408
2009 Burgon TB, Jenkins JA, Deitz SB, Spagnolo JF, Kirkegaard K. Bypass suppression of small-plaque phenotypes by a mutation in poliovirus 2A that enhances apoptosis. Journal of Virology. 83: 10129-39. PMID 19625405 DOI: 10.1128/Jvi.00642-09  0.773
2009 Taylor MP, Burgon TB, Kirkegaard K, Jackson WT. Role of microtubules in extracellular release of poliovirus. Journal of Virology. 83: 6599-609. PMID 19369338 DOI: 10.1128/Jvi.01819-08  0.803
2008 Taylor MP, Kirkegaard K. Potential subversion of autophagosomal pathway by picornaviruses. Autophagy. 4: 286-9. PMID 18094610 DOI: 10.4161/Auto.5377  0.528
2008 Tellez A, Wang J, Spagnolo J, Kirkegaard K, Bullitt E. Intermolecular Contacts Required to Form Planar Lattices of Poliovirus RNA-dependent RNA Polymerase Microscopy and Microanalysis. 14: 1306-1307. DOI: 10.1017/S1431927608082044  0.794
2007 Taylor MP, Kirkegaard K. Modification of cellular autophagy protein LC3 by poliovirus. Journal of Virology. 81: 12543-53. PMID 17804493 DOI: 10.1128/Jvi.00755-07  0.451
2007 Beske O, Reichelt M, Taylor MP, Kirkegaard K, Andino R. Poliovirus infection blocks ERGIC-to-Golgi trafficking and induces microtubule-dependent disruption of the Golgi complex. Journal of Cell Science. 120: 3207-18. PMID 17711878 DOI: 10.1242/Jcs.03483  0.606
2006 Richards OC, Spagnolo JF, Lyle JM, Vleck SE, Kuchta RD, Kirkegaard K. Intramolecular and intermolecular uridylylation by poliovirus RNA-dependent RNA polymerase. Journal of Virology. 80: 7405-15. PMID 16840321 DOI: 10.1128/Jvi.02533-05  0.818
2006 Pfeiffer JK, Kirkegaard K. Bottleneck-mediated quasispecies restriction during spread of an RNA virus from inoculation site to brain. Proceedings of the National Academy of Sciences of the United States of America. 103: 5520-5. PMID 16567621 DOI: 10.1073/Pnas.0600834103  0.71
2006 Tellez AB, Crowder S, Spagnolo JF, Thompson AA, Peersen OB, Brutlag DL, Kirkegaard K. Nucleotide channel of RNA-dependent RNA polymerase used for intermolecular uridylylation of protein primer. Journal of Molecular Biology. 357: 665-75. PMID 16427083 DOI: 10.1016/J.Jmb.2005.12.044  0.799
2005 Kirkegaard K, Jackson WT. Topology of double-membraned vesicles and the opportunity for non-lytic release of cytoplasm. Autophagy. 1: 182-4. PMID 16874042 DOI: 10.4161/Auto.1.3.2065  0.668
2005 Pfeiffer JK, Kirkegaard K. Increased fidelity reduces poliovirus fitness and virulence under selective pressure in mice. Plos Pathogens. 1: e11. PMID 16220146 DOI: 10.1371/Journal.Ppat.0010011  0.695
2005 Crowder S, Kirkegaard K. Trans-dominant inhibition of RNA viral replication can slow growth of drug-resistant viruses. Nature Genetics. 37: 701-9. PMID 15965477 DOI: 10.1038/Ng1583  0.494
2005 Boerner JE, Lyle JM, Daijogo S, Semler BL, Schultz SC, Kirkegaard K, Richards OC. Allosteric effects of ligands and mutations on poliovirus RNA-dependent RNA polymerase. Journal of Virology. 79: 7803-11. PMID 15919933 DOI: 10.1128/Jvi.79.12.7803-7811.2005  0.814
2005 Choe SS, Dodd DA, Kirkegaard K. Inhibition of cellular protein secretion by picornaviral 3A proteins. Virology. 337: 18-29. PMID 15914217 DOI: 10.1016/J.Virol.2005.03.036  0.76
2005 Jackson WT, Giddings TH, Taylor MP, Mulinyawe S, Rabinovitch M, Kopito RR, Kirkegaard K. Subversion of cellular autophagosomal machinery by RNA viruses. Plos Biology. 3: e156. PMID 15884975 DOI: 10.1371/Journal.Pbio.0030156  0.715
2005 Pfeiffer JK, Kirkegaard K. Ribavirin resistance in hepatitis C virus replicon-containing cell lines conferred by changes in the cell line or mutations in the replicon RNA. Journal of Virology. 79: 2346-55. PMID 15681435 DOI: 10.1128/Jvi.79.4.2346-2355.2005  0.684
2004 Crowder S, Kirkegaard K. Complete three-dimensional structures of picornaviral RNA-dependent RNA polymerases. Structure (London, England : 1993). 12: 1336-9. PMID 15296725 DOI: 10.1016/J.Str.2004.07.003  0.445
2004 Choe SS, Kirkegaard K. Intracellular topology and epitope shielding of poliovirus 3A protein. Journal of Virology. 78: 5973-82. PMID 15140995 DOI: 10.1128/Jvi.78.11.5973-5982.2004  0.831
2004 Kirkegaard K, Taylor MP, Jackson WT. Cellular autophagy: surrender, avoidance and subversion by microorganisms. Nature Reviews. Microbiology. 2: 301-14. PMID 15031729 DOI: 10.1038/Nrmicro865  0.603
2003 Konan KV, Giddings TH, Ikeda M, Li K, Lemon SM, Kirkegaard K. Nonstructural protein precursor NS4A/B from hepatitis C virus alters function and ultrastructure of host secretory apparatus. Journal of Virology. 77: 7843-55. PMID 12829824 DOI: 10.1128/Jvi.77.14.7843-7855.2003  0.372
2003 Pfeiffer JK, Kirkegaard K. A single mutation in poliovirus RNA-dependent RNA polymerase confers resistance to mutagenic nucleotide analogs via increased fidelity. Proceedings of the National Academy of Sciences of the United States of America. 100: 7289-94. PMID 12754380 DOI: 10.1073/Pnas.1232294100  0.72
2002 Lyle JM, Bullitt E, Bienz K, Kirkegaard K. Visualization and functional analysis of RNA-dependent RNA polymerase lattices. Science (New York, N.Y.). 296: 2218-22. PMID 12077417 DOI: 10.1126/Science.1070585  0.82
2002 Wang QM, Hockman MA, Staschke K, Johnson RB, Case KA, Lu J, Parsons S, Zhang F, Rathnachalam R, Kirkegaard K, Colacino JM. Oligomerization and cooperative RNA synthesis activity of hepatitis C virus RNA-dependent RNA polymerase. Journal of Virology. 76: 3865-72. PMID 11907226 DOI: 10.1128/Jvi.76.8.3865-3872.2002  0.451
2002 Lyle JM, Clewell A, Richmond K, Richards OC, Hope DA, Schultz SC, Kirkegaard K. Similar structural basis for membrane localization and protein priming by an RNA-dependent RNA polymerase. The Journal of Biological Chemistry. 277: 16324-31. PMID 11877407 DOI: 10.1074/Jbc.M112429200  0.802
2001 Schneider R, Agol VI, Andino R, Bayard F, Cavener DR, Chappell SA, Chen JJ, Darlix JL, Dasgupta A, Donzé O, Duncan R, Elroy-Stein O, Farabaugh PJ, Filipowicz W, Gale M, ... ... Kirkegaard K, et al. New ways of initiating translation in eukaryotes. Molecular and Cellular Biology. 21: 8238-46. PMID 11710333 DOI: 10.1128/Mcb.21.23.8238-8246.2001  0.639
2001 Dodd DA, Giddings TH, Kirkegaard K. Poliovirus 3A protein limits interleukin-6 (IL-6), IL-8, and beta interferon secretion during viral infection. Journal of Virology. 75: 8158-65. PMID 11483761 DOI: 10.1128/Jvi.75.17.8158-8165.2001  0.8
2001 Hobson SD, Rosenblum ES, Richards OC, Richmond K, Kirkegaard K, Schultz SC. Oligomeric structures of poliovirus polymerase are important for function. The Embo Journal. 20: 1153-63. PMID 11230138 DOI: 10.1093/Emboj/20.5.1153  0.504
2000 Deitz SB, Dodd DA, Cooper S, Parham P, Kirkegaard K. MHC I-dependent antigen presentation is inhibited by poliovirus protein 3A. Proceedings of the National Academy of Sciences of the United States of America. 97: 13790-5. PMID 11095746 DOI: 10.1073/Pnas.250483097  0.794
2000 Suhy DA, Giddings TH, Kirkegaard K. Remodeling the endoplasmic reticulum by poliovirus infection and by individual viral proteins: an autophagy-like origin for virus-induced vesicles. Journal of Virology. 74: 8953-65. PMID 10982339 DOI: 10.1128/Jvi.74.19.8953-8965.2000  0.484
1999 Nugent CI, Johnson KL, Sarnow P, Kirkegaard K. Functional coupling between replication and packaging of poliovirus replicon RNA. Journal of Virology. 73: 427-35. PMID 9847348 DOI: 10.1128/Jvi.73.1.427-435.1999  0.523
1998 Xiang W, Cuconati A, Hope D, Kirkegaard K, Wimmer E. Complete protein linkage map of poliovirus P3 proteins: interaction of polymerase 3Dpol with VPg and with genetic variants of 3AB. Journal of Virology. 72: 6732-41. PMID 9658121 DOI: 10.1128/Jvi.72.8.6732-6741.1998  0.466
1998 McBride AE, Taylor SJ, Shalloway D, Kirkegaard K. KH domain integrity is required for wild-type localization of Sam68 Experimental Cell Research. 241: 84-95. PMID 9633516 DOI: 10.1006/Excr.1998.4047  0.428
1998 Beckman MT, Kirkegaard K. Site size of cooperative single-stranded RNA binding by poliovirus RNA-dependent RNA polymerase. The Journal of Biological Chemistry. 273: 6724-30. PMID 9506971 DOI: 10.1074/Jbc.273.12.6724  0.447
1997 Hope DA, Diamond SE, Kirkegaard K. Genetic dissection of interaction between poliovirus 3D polymerase and viral protein 3AB. Journal of Virology. 71: 9490-8. PMID 9371611 DOI: 10.1128/Jvi.71.12.9490-9498.1997  0.504
1997 Doedens JR, Giddings TH, Kirkegaard K. Inhibition of endoplasmic reticulum-to-Golgi traffic by poliovirus protein 3A: genetic and ultrastructural analysis. Journal of Virology. 71: 9054-64. PMID 9371562 DOI: 10.1128/Jvi.71.12.9054-9064.1997  0.42
1997 Van kuppeveld FJ, Melchers WJ, Kirkegaard K, Doedens JR. Structure-function analysis of coxsackie B3 virus protein 2B. Virology. 227: 111-8. PMID 9007064 DOI: 10.1006/Viro.1996.8320  0.353
1996 Schlegel A, Giddings TH, Ladinsky MS, Kirkegaard K. Cellular origin and ultrastructure of membranes induced during poliovirus infection. Journal of Virology. 70: 6576-88. PMID 8794292 DOI: 10.1128/Jvi.70.10.6576-6588.1996  0.423
1996 McBride AE, Schlegel A, Kirkegaard K. Human protein Sam68 relocalization and interaction with poliovirus RNA polymerase in infected cells. Proceedings of the National Academy of Sciences of the United States of America. 93: 2296-301. PMID 8637866 DOI: 10.1073/Pnas.93.6.2296  0.524
1995 Nugent CI, Kirkegaard K. RNA binding properties of poliovirus subviral particles. Journal of Virology. 69: 13-22. PMID 7983702 DOI: 10.1128/Jvi.69.1.13-22.1995  0.48
1995 Doedens J, Kirkegaard K. Inhibition of cellular protein secretion by poliovirus proteins 2B and 3A. The Embo Journal. 14: 894-907. DOI: 10.1002/J.1460-2075.1995.Tb07071.X  0.485
1994 Diamond SE, Kirkegaard K. Clustered charged-to-alanine mutagenesis of poliovirus RNA-dependent RNA polymerase yields multiple temperature-sensitive mutants defective in RNA synthesis Journal of Virology. 68: 863-876. PMID 8289389 DOI: 10.1128/Jvi.68.2.863-876.1994  0.435
1994 Doedens J, Maynell LA, Klymkowsky MW, Kirkegaard K. Secretory pathway function, but not cytoskeletal integrity, is required in poliovirus infection. Archives of Virology. Supplementum. 9: 159-72. PMID 8032247 DOI: 10.1007/978-3-7091-9326-6_16  0.49
1994 Novak JE, Kirkegaard K. Coupling between genome translation and replication in an RNA virus. Genes & Development. 8: 1726-37. PMID 7958852 DOI: 10.1101/Gad.8.14.1726  0.484
1992 Kirkegaard K. Genetic analysis of picornaviruses. Current Opinion in Genetics & Development. 2: 64-70. PMID 1321679 DOI: 10.1016/0960-9822(92)90194-F  0.482
1992 Maynell LA, Kirkegaard K, Klymkowsky MW. Inhibition of poliovirus RNA synthesis by brefeldin A. Journal of Virology. 66: 1985-94. PMID 1312615 DOI: 10.1128/Jvi.66.4.1985-1994.1992  0.524
1992 Jarvis T, Kirkegaard K. Poliovirus RNA recombination: mechanistic studies in the absence of selection. The Embo Journal. 11: 3135-3145. DOI: 10.1002/J.1460-2075.1992.Tb05386.X  0.474
1991 Novak JE, Kirkegaard K. Improved method for detecting poliovirus negative strands used to demonstrate specificity of positive-strand encapsidation and the ratio of positive to negative strands in infected cells. Journal of Virology. 65: 3384-7. PMID 1851886 DOI: 10.1128/Jvi.65.6.3384-3387.1991  0.434
1991 Jarvis TC, Kirkegaard K. The polymerase in its labyrinth: mechanisms and implications of RNA recombination Trends in Genetics. 7: 186-191. PMID 1712518 DOI: 10.1016/0168-9525(91)90434-R  0.467
1991 Morrissey LM, Kirkegaard K. Regulation of a double-stranded RNA modification activity in human cells. Molecular and Cellular Biology. 11: 3719-25. PMID 1646394 DOI: 10.1128/Mcb.11.7.3719  0.45
1990 Compton SR, Nelsen B, Kirkegaard K. Temperature-sensitive poliovirus mutant fails to cleave VP0 and accumulates provirions Journal of Virology. 64: 4067-4075. PMID 2166805 DOI: 10.1128/Jvi.64.9.4067-4075.1990  0.454
1990 Kirkegaard K. Mutations in VP1 of poliovirus specifically affect both encapsidation and release of viral RNA. Journal of Virology. 64: 195-206. PMID 2152812 DOI: 10.1128/Jvi.64.1.195-206.1990  0.51
1990 Kirkegaard K, Nelsen B. Conditional poliovirus mutants made by random deletion mutagenesis of infectious cDNA. Journal of Virology. 64: 185-94. PMID 2152811 DOI: 10.1128/Jvi.64.1.185-194.1990  0.386
1988 Kirkegaard K. The molecular basis of viral replication Trends in Genetics. 4: 239-240. DOI: 10.1016/0168-9525(88)90160-6  0.386
1986 Kirkegaard K, Baltimore D. The mechanism of RNA recombination in poliovirus. Cell. 47: 433-43. PMID 3021340 DOI: 10.1016/0092-8674(86)90600-8  0.462
1985 Kirkegaard K, Pflugfelder G, Wang JC. The cleavage of DNA by type-I DNA topoisomerases. Cold Spring Harbor Symposia On Quantitative Biology. 49: 411-9. PMID 6099250 DOI: 10.1101/Sqb.1984.049.01.047  0.418
1985 Spassky A, Kirkegaard K, Buc H. Changes in the DNA structure of the lac UV5 promoter during formation of an open complex with Escherichia coli RNA polymerase. Biochemistry. 24: 2723-31. PMID 3896305 DOI: 10.1021/Bi00332A019  0.373
1985 Kirkegaard K, Wang JC. Bacterial DNA topoisomerase I can relax positively supercoiled DNA containing a single-stranded loop. Journal of Molecular Biology. 185: 625-37. PMID 2997454 DOI: 10.1016/0022-2836(85)90075-0  0.457
1983 Kirkegaard K, Buc H, Spassky A, Wang JC. Mapping of single-stranded regions in duplex DNA at the sequence level: single-strand-specific cytosine methylation in RNA polymerase-promoter complexes. Proceedings of the National Academy of Sciences of the United States of America. 80: 2544-8. PMID 6573669 DOI: 10.1073/Pnas.80.9.2544  0.533
1981 Kirkegaard K, Wang JC. Mapping the topography of DNA wrapped around gyrase by nucleolytic and chemical probing of complexes of unique DNA sequences. Cell. 23: 721-9. PMID 6261954 DOI: 10.1016/0092-8674(81)90435-9  0.433
1979 Kirkegaard K, Wang JC. Escherichia coli DNA topoisomerase I catalyzed linking of single-stranded rings of complementary base sequences. Nucleic Acids Research. 5: 3811-20. PMID 214763 DOI: 10.1093/Nar/5.10.3811  0.452
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