| Year |
Citation |
Score |
| 2018 |
Bouvier JT, Sernova NV, Ghasempur S, Rodionova IA, Vetting MW, Al-Obaidi NF, Almo SC, Gerlt JA, Rodionov DA. Novel Metabolic Pathways and Regulons for Hexuronate Utilization in Proteobacteria. Journal of Bacteriology. PMID 30249705 DOI: 10.1128/Jb.00431-18 |
0.36 |
|
| 2018 |
Carter MS, Zhang X, Huang H, Bouvier JT, Francisco BS, Vetting MW, Al-Obaidi N, Bonanno JB, Ghosh A, Zallot RG, Andersen HM, Almo SC, Gerlt JA. Functional assignment of multiple catabolic pathways for D-apiose. Nature Chemical Biology. PMID 29867142 DOI: 10.1038/S41589-018-0067-7 |
0.375 |
|
| 2018 |
Calhoun S, Korczynska M, Wichelecki DJ, San Francisco B, Zhao S, Rodionov DA, Vetting MW, Al-Obaidi NF, Lin H, O'Meara MJ, Scott DA, Morris JH, Russel D, Almo SC, Osterman AL, et al. Prediction of enzymatic pathways by integrative pathway mapping. Elife. 7. PMID 29377793 DOI: 10.7554/Elife.31097 |
0.363 |
|
| 2017 |
Rodionova IA, Vetting MW, Li X, Almo SC, Osterman AL, Rodionov DA. A novel bifunctional transcriptional regulator of riboflavin metabolism in Archaea. Nucleic Acids Research. PMID 28073944 DOI: 10.1093/Nar/Gkw1331 |
0.336 |
|
| 2016 |
Zhang X, Carter MS, Vetting MW, San Francisco B, Zhao S, Al-Obaidi NF, Solbiati JO, Thiaville JJ, de Crécy-Lagard V, Jacobson MP, Almo SC, Gerlt JA. Assignment of function to a domain of unknown function: DUF1537 is a new kinase family in catabolic pathways for acid sugars. Proceedings of the National Academy of Sciences of the United States of America. PMID 27402745 DOI: 10.1073/Pnas.1605546113 |
0.369 |
|
| 2016 |
Yadava U, Vetting MW, Al Obaidi N, Carter MS, Gerlt JA, Almo SC. Structure of an ABC transporter solute-binding protein specific for the amino sugars glucosamine and galactosamine. Acta Crystallographica. Section F, Structural Biology Communications. 72: 467-472. PMID 27303900 DOI: 10.1107/S2053230X16007500 |
0.349 |
|
| 2016 |
Vetting MW, Bouvier JT, Gerlt JA, Almo SC. Purification, crystallization and structural elucidation of D-galactaro-1,4-lactone cycloisomerase from Agrobacterium tumefaciens involved in pectin degradation. Acta Crystallographica. Section F, Structural Biology Communications. 72: 36-41. PMID 26750482 DOI: 10.1107/S2053230X15023286 |
0.409 |
|
| 2015 |
Huang H, Carter MS, Vetting MW, Al-Obaidi N, Patskovsky Y, Almo SC, Gerlt JA. A General Strategy for the Discovery of Metabolic Pathways: D-Threitol, L-Threitol, and Erythritol Utilization in Mycobacterium smegmatis. Journal of the American Chemical Society. PMID 26560079 DOI: 10.1021/Jacs.5B08968 |
0.369 |
|
| 2015 |
Wichelecki DJ, Vetting MW, Chou L, Al-Obaidi N, Bouvier JT, Almo SC, Gerlt JA. ABC Transport System Solute Binding Protein-Guided Identification of Novel D-Altritol and Galactitol Catabolic Pathways in Agrobacterium tumefaciencs C58. The Journal of Biological Chemistry. PMID 26472925 DOI: 10.1074/Jbc.M115.686857 |
0.387 |
|
| 2015 |
Zhang X, Kumar R, Vetting MW, Zhao S, Jacobson MP, Almo SC, Gerlt JA. A unique cis-3-hydroxy-l-proline dehydratase in the enolase superfamily. Journal of the American Chemical Society. 137: 1388-91. PMID 25608448 DOI: 10.1021/Ja5103986 |
0.328 |
|
| 2015 |
Vetting MW, Al-Obaidi N, Zhao S, San Francisco B, Kim J, Wichelecki DJ, Bouvier JT, Solbiati JO, Vu H, Zhang X, Rodionov DA, Love JD, Hillerich BS, Seidel RD, Quinn RJ, et al. Experimental strategies for functional annotation and metabolism discovery: targeted screening of solute binding proteins and unbiased panning of metabolomes. Biochemistry. 54: 909-31. PMID 25540822 DOI: 10.1021/Bi501388Y |
0.311 |
|
| 2014 |
Groninger-Poe FP, Bouvier JT, Vetting MW, Kalyanaraman C, Kumar R, Almo SC, Jacobson MP, Gerlt JA. Evolution of enzymatic activities in the enolase superfamily: galactarate dehydratase III from Agrobacterium tumefaciens C58. Biochemistry. 53: 4192-203. PMID 24926996 DOI: 10.1021/Bi5005377 |
0.343 |
|
| 2014 |
Mashiyama ST, Malabanan MM, Akiva E, Bhosle R, Branch MC, Hillerich B, Jagessar K, Kim J, Patskovsky Y, Seidel RD, Stead M, Toro R, Vetting MW, Almo SC, Armstrong RN, et al. Large-scale determination of sequence, structure, and function relationships in cytosolic glutathione transferases across the biosphere. Plos Biology. 12: e1001843. PMID 24756107 DOI: 10.1371/Journal.Pbio.1001843 |
0.368 |
|
| 2014 |
Kumar R, Zhao S, Vetting MW, Wood BM, Sakai A, Cho K, Solbiati J, Almo SC, Sweedler JV, Jacobson MP, Gerlt JA, Cronan JE. Prediction and biochemical demonstration of a catabolic pathway for the osmoprotectant proline betaine. Mbio. 5: e00933-13. PMID 24520058 DOI: 10.1128/Mbio.00933-13 |
0.356 |
|
| 2014 |
Bouvier JT, Groninger-Poe FP, Vetting M, Almo SC, Gerlt JA. Galactaro δ-lactone isomerase: Lactone isomerization by a member of the amidohydrolase superfamily Biochemistry. 53: 614-616. PMID 24450804 DOI: 10.1021/Bi5000492 |
0.325 |
|
| 2014 |
Cummings JA, Vetting M, Ghodge SV, Xu C, Hillerich B, Seidel RD, Almo SC, Raushel FM. Prospecting for unannotated enzymes: discovery of a 3',5'-nucleotide bisphosphate phosphatase within the amidohydrolase superfamily. Biochemistry. 53: 591-600. PMID 24401123 DOI: 10.1021/Bi401640R |
0.443 |
|
| 2013 |
Zhao S, Kumar R, Sakai A, Vetting MW, Wood BM, Brown S, Bonanno JB, Hillerich BS, Seidel RD, Babbitt PC, Almo SC, Sweedler JV, Gerlt JA, Cronan JE, Jacobson MP. Discovery of new enzymes and metabolic pathways by using structure and genome context. Nature. 502: 698-702. PMID 24056934 DOI: 10.1038/Nature12576 |
0.409 |
|
| 2013 |
Hitchcock DS, Fan H, Kim J, Vetting M, Hillerich B, Seidel RD, Almo SC, Shoichet BK, Sali A, Raushel FM. Structure-guided discovery of new deaminase enzymes. Journal of the American Chemical Society. 135: 13927-33. PMID 23968233 DOI: 10.1021/Ja4066078 |
0.452 |
|
| 2012 |
Lukk T, Sakai A, Kalyanaraman C, Brown SD, Imker HJ, Song L, Fedorov AA, Fedorov EV, Toro R, Hillerich B, Seidel R, Patskovsky Y, Vetting MW, Nair SK, Babbitt PC, et al. Homology models guide discovery of diverse enzyme specificities among dipeptide epimerases in the enolase superfamily. Proceedings of the National Academy of Sciences of the United States of America. 109: 4122-7. PMID 22392983 DOI: 10.1073/Pnas.1112081109 |
0.45 |
|
| 2011 |
Vetting MW, Hegde SS, Wang M, Jacoby GA, Hooper DC, Blanchard JS. Structure of QnrB1, a plasmid-mediated fluoroquinolone resistance factor Journal of Biological Chemistry. 286: 25265-25273. PMID 21597116 DOI: 10.1074/Jbc.M111.226936 |
0.341 |
|
| 2011 |
Vetting MW, Hegde SS, Zhang Y, Blanchard JS. Pentapeptide-repeat proteins that act as topoisomerase poison resistance factors have a common dimer interface Acta Crystallographica Section F: Structural Biology and Crystallization Communications. 67: 296-302. PMID 21393830 DOI: 10.1107/S1744309110053315 |
0.31 |
|
| 2011 |
Hegde SS, Vetting MW, Mitchenall LA, Maxwell A, Blanchard JS. Structural and biochemical analysis of the pentapeptide repeat protein EfsQnr, a potent DNA gyrase inhibitor Antimicrobial Agents and Chemotherapy. 55: 110-117. PMID 20937785 DOI: 10.1128/Aac.01158-10 |
0.364 |
|
| 2010 |
Vetting MW, Hegde SS, Blanchard JS. The structure and mechanism of the Mycobacterium tuberculosis cyclodityrosine synthetase Nature Chemical Biology. 6: 797-799. PMID 20852636 DOI: 10.1038/Nchembio.440 |
0.437 |
|
| 2009 |
Fan F, Vetting MW, Frantom PA, Blanchard JS. Structures and mechanisms of the mycothiol biosynthetic enzymes. Current Opinion in Chemical Biology. 13: 451-9. PMID 19699138 DOI: 10.1016/J.Cbpa.2009.07.018 |
0.405 |
|
| 2009 |
Andreassi JL, Vetting MW, Bilder PW, Roderick SL, Leyh TS. Structure of the ternary complex of phosphomevalonate kinase: the enzyme and its family. Biochemistry. 48: 6461-8. PMID 19485344 DOI: 10.1021/Bi900537U |
0.406 |
|
| 2009 |
Vetting MW, Hegde SS, Blanchard JS. Crystallization of a pentapeptide-repeat protein by reductive cyclic pentylation of free amines with glutaraldehyde Acta Crystallographica Section D: Biological Crystallography. 65: 462-469. PMID 19390151 DOI: 10.1107/S0907444909008324 |
0.351 |
|
| 2009 |
Fan F, Vetting MW, Frantom PA, Blanchard JS. Structures and mechanisms of the mycothiol biosynthetic enzymes Current Opinion in Chemical Biology. 13: 444-452. DOI: 10.1016/j.cbpa.2009.07.018 |
0.31 |
|
| 2008 |
Tremblay LW, Fan F, Vetting MW, Blanchard JS. The 1.6 Å crystal structure of Mycobacterium smegmatis MshC: The penultimate enzyme in the mycothiol biosynthetic pathway Biochemistry. 47: 13326-13335. PMID 19053270 DOI: 10.1021/Bi801708F |
0.413 |
|
| 2008 |
Vetting MW, Errey JC, Blanchard JS. Rv0802c from Mycobacterium tuberculosis: The first structure of a succinyltransferase with the GNAT fold Acta Crystallographica Section F: Structural Biology and Crystallization Communications. 64: 978-985. PMID 18997321 DOI: 10.1107/S1744309108031679 |
0.431 |
|
| 2008 |
Vetting MW, Chi HP, Hegde SS, Jacoby GA, Hooper DC, Blanchard JS. Mechanistic and structural analysis of aminoglycoside N-acetyltransferase AAC(6′)-Ib and its bifunctional, fluoroquinolone-active AAC(6′)-Ib-cr variant Biochemistry. 47: 9825-9835. PMID 18710261 DOI: 10.1021/Bi800664X |
0.422 |
|
| 2008 |
Vetting MW, Bareich DC, Yu M, Blanchard JS. Crystal structure of RimI from Salmonella typhimurium LT2, the GNAT responsible for Nα-acetylation of ribosomal protein S18 Protein Science. 17: 1781-1790. PMID 18596200 DOI: 10.1110/Ps.035899.108 |
0.403 |
|
| 2008 |
Vetting MW, Frantom PA, Blanchard JS. Structural and enzymatic analysis of MshA from Corynebacterium glutamicum: Substrate-assisted catalysis Journal of Biological Chemistry. 283: 15834-15844. PMID 18390549 DOI: 10.1074/Jbc.M801017200 |
0.411 |
|
| 2008 |
Magalhães MLB, Vetting MW, Gao F, Freiburger L, Auclair K, Blanchard JS. Kinetic and structural analysis of bisubstrate inhibition of the Salmonella enterica aminoglycoside 6′-N-acetyltransferase Biochemistry. 47: 579-584. PMID 18095712 DOI: 10.1021/Bi701957C |
0.469 |
|
| 2007 |
Argyrou A, Vetting MW, Blanchard JS. New insight into the mechanism of action of and resistance to isoniazid: Interaction of Mycobacterium tuberculosis enoyl-ACP reductase with INH-NADP Journal of the American Chemical Society. 129: 9582-9583. PMID 17636923 DOI: 10.1021/Ja073160K |
0.407 |
|
| 2007 |
Hegde SS, Chandler J, Vetting MW, Yu M, Blanchard JS. Mechanistic and structural analysis of human spermidine/spermine N1-acetyltransferase. Biochemistry. 46: 7187-95. PMID 17516632 DOI: 10.1021/Bi700256Z |
0.444 |
|
| 2007 |
Olsen LR, Vetting MW, Roderick SL. Structure of the E. coli bifunctional GlmU acetyltransferase active site with substrates and products. Protein Science : a Publication of the Protein Society. 16: 1230-5. PMID 17473010 DOI: 10.1110/Ps.072779707 |
0.486 |
|
| 2007 |
Andreassi JL, Bilder PW, Vetting MW, Roderick SL, Leyh TS. Crystal structure of the Streptococcus pneumoniae mevalonate kinase in complex with diphosphomevalonate. Protein Science : a Publication of the Protein Society. 16: 983-9. PMID 17400916 DOI: 10.1110/Ps.072755707 |
0.331 |
|
| 2006 |
Vetting MW, Hegde SS, Fajardo JE, Fiser A, Roderick SL, Takiff HE, Blanchard JS. Pentapeptide repeat proteins Biochemistry. 45: 1-10. PMID 16388575 DOI: 10.1021/Bi052130W |
0.367 |
|
| 2006 |
Vetting MW, Yu M, Rendle PM, Blanchard JS. The substrate-induced conformational change of mycobacterium tuberculosis mycothiol synthase Journal of Biological Chemistry. 281: 2795-2802. PMID 16326705 DOI: 10.1074/Jbc.M510798200 |
0.441 |
|
| 2005 |
Earhart CA, Vetting MW, Gosu R, Michaud-Soret I, Que L, Ohlendorf DH. Structure of catechol 1,2-dioxygenase from Pseudomonas arvilla. Biochemical and Biophysical Research Communications. 338: 198-205. PMID 16171781 DOI: 10.1016/J.Bbrc.2005.08.221 |
0.644 |
|
| 2005 |
Valley MP, Brown CK, Burk DL, Vetting MW, Ohlendorf DH, Lipscomb JD. Roles of the equatorial tyrosyl iron ligand of protocatechuate 3,4-dioxygenase in catalysis. Biochemistry. 44: 11024-39. PMID 16101286 DOI: 10.1021/Bi050902I |
0.634 |
|
| 2005 |
Huang B, Vetting MW, Roderick SL. The active site of O-acetylserine sulfhydrylase is the anchor point for bienzyme complex formation with serine acetyltransferase. Journal of Bacteriology. 187: 3201-5. PMID 15838047 DOI: 10.1128/Jb.187.9.3201-3205.2005 |
0.361 |
|
| 2005 |
Vetting MW, De Carvalho LPS, Roderick SL, Blanchard JS. A novel dimeric structure of the RimL Nα-acetyltransferase from Salmonella typhimurium Journal of Biological Chemistry. 280: 22108-22114. PMID 15817456 DOI: 10.1074/Jbc.M502401200 |
0.407 |
|
| 2005 |
Vetting MW, Luiz LP, Yu M, Hegde SS, Magnet S, Roderick SL, Blanchard JS. Structure and functions of the GNAT superfamily of acetyltransferases Archives of Biochemistry and Biophysics. 433: 212-226. PMID 15581578 DOI: 10.1016/J.Abb.2004.09.003 |
0.365 |
|
| 2004 |
Brown CK, Vetting MW, Earhart CA, Ohlendorf DH. Biophysical analyses of designed and selected mutants of protocatechuate 3,4-dioxygenase1. Annual Review of Microbiology. 58: 555-85. PMID 15487948 DOI: 10.1146/Annurev.Micro.57.030502.090927 |
0.625 |
|
| 2004 |
Argyrou A, Vetting MW, Blanchard JS. Characterization of a new member of the flavoprotein disulfide reductase family of enzymes from Mycobacterium tuberculosis Journal of Biological Chemistry. 279: 52694-52702. PMID 15456792 DOI: 10.1074/Jbc.M410704200 |
0.452 |
|
| 2004 |
Olsen LR, Huang B, Vetting MW, Roderick SL. Structure of serine acetyltransferase in complexes with CoA and its cysteine feedback inhibitor. Biochemistry. 43: 6013-9. PMID 15147185 DOI: 10.1021/Bi0358521 |
0.49 |
|
| 2004 |
Vetting MW, Magnet S, Nieves E, Roderick SL, Blanchard JS. A bacterial acetyltransferase capable of regioselective N-acetylation of antibiotics and histones Chemistry and Biology. 11: 565-573. PMID 15123251 DOI: 10.1016/J.Chembiol.2004.03.017 |
0.373 |
|
| 2004 |
Vetting MW, Wackett LP, Que L, Lipscomb JD, Ohlendorf DH. Crystallographic comparison of manganese- and iron-dependent homoprotocatechuate 2,3-dioxygenases. Journal of Bacteriology. 186: 1945-58. PMID 15028678 DOI: 10.1128/Jb.186.7.1945-1958.2004 |
0.648 |
|
| 2003 |
Vetting MW, Roderick SL, Yu M, Blanchard JS. Crystal structure of mycothiol synthase (Rv0819) from Mycobacterium tuberculosis shows structural homology to the GNAT family of N-acetyltransferases Protein Science. 12: 1954-1959. PMID 12930994 DOI: 10.1110/Ps.03153703 |
0.45 |
|
| 2003 |
Vetting M, Roderick SL, Hegde S, Magnet S, Blanchard JS. What can structure tell us about in vivo function? The case of aminoglycoside-resistance genes. Biochemical Society Transactions. 31: 520-2. PMID 12773148 DOI: 10.1042/Bst0310520 |
0.365 |
|
| 2002 |
Vetting MW, Hegde SS, Javid-Majd F, Blanchard JS, Roderick SL. Aminoglycoside 2'-N-acetyltransferase from Mycobacterium tuberculosis in complex with coenzyme A and aminoglycoside substrates. Nature Structural Biology. 9: 653-8. PMID 12161746 DOI: 10.1038/Nsb830 |
0.414 |
|
| 2000 |
Vetting MW, D'Argenio DA, Ornston LN, Ohlendorf DH. Structure of Acinetobacter strain ADP1 protocatechuate 3, 4-dioxygenase at 2.2 A resolution: implications for the mechanism of an intradiol dioxygenase. Biochemistry. 39: 7943-55. PMID 10891075 DOI: 10.1021/Bi000151E |
0.651 |
|
| 2000 |
Vetting MW, Ohlendorf DH. The 1.8 A crystal structure of catechol 1,2-dioxygenase reveals a novel hydrophobic helical zipper as a subunit linker. Structure (London, England : 1993). 8: 429-40. PMID 10801478 DOI: 10.1016/S0969-2126(00)00122-2 |
0.643 |
|
| 1999 |
D'Argenio DA, Vetting MW, Ohlendorf DH, Ornston LN. Substitution, insertion, deletion, suppression, and altered substrate specificity in functional protocatechuate 3,4-dioxygenases. Journal of Bacteriology. 181: 6478-87. PMID 10515940 DOI: 10.1128/Jb.181.20.6478-6487.1999 |
0.589 |
|
| 1994 |
Vetting MW, Earhart CA, Ohlendorf DH. Crystallization and preliminary X-ray analysis of protocatechuate 3,4-dioxygenase from Acinetobacter calcoaceticus. Journal of Molecular Biology. 236: 372-3. PMID 8107118 DOI: 10.1006/Jmbi.1994.1142 |
0.59 |
|
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