Nathan R. Treff, Ph.D. - Publications

Affiliations: 
2003 Washington State University, Pullman, WA, United States 
Area:
Molecular Biology, Genetics, Cell Biology

137 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Rana B, Lambrese K, Mendola R, Xu J, Garrisi J, Miller K, Marin D, Treff NR. Identifying parental and cell-division origins of aneuploidy in the human blastocyst. American Journal of Human Genetics. 110: 565-574. PMID 36977411 DOI: 10.1016/j.ajhg.2023.03.003  0.31
2020 Marin D, Xu J, Treff NR. Preimplantation Genetic Testing for Aneuploidy: A Review of Published Blastocyst Reanalysis Concordance Data. Prenatal Diagnosis. PMID 32920823 DOI: 10.1002/Pd.5828  0.349
2019 Zimmerman RS, Eccles J, Jalas C, Treff NR, Scott RT. Molecular Testing for Preimplantation Genetic Diagnosis of Single Gene Disorders. Methods in Molecular Biology (Clifton, N.J.). 1885: 61-71. PMID 30506190 DOI: 10.1007/978-1-4939-8889-1_4  0.336
2018 Green KA, Franasiak JM, Werner MD, Tao X, Landis JN, Scott RT, Treff NR. Cumulus cell transcriptome profiling is not predictive of live birth after in vitro fertilization: a paired analysis of euploid sibling blastocysts. Fertility and Sterility. PMID 29428306 DOI: 10.1016/J.Fertnstert.2017.11.002  0.344
2018 Marin D, Zimmerman R, Tao X, Zhan Y, Scott RT, Treff NR. Validation of a targeted next generation sequencing-based comprehensive chromosome screening platform for detection of triploidy in human blastocysts. Reproductive Biomedicine Online. PMID 29366772 DOI: 10.1016/J.Rbmo.2017.12.015  0.344
2017 Zimmerman RS, Tao X, Marin D, Werner M, Hong K, Lonczak A, Landis J, Taylor D, Zhan Y, Scott RT, Treff NR. Preclinical Validation of a Targeted Next Generation Sequencing-based Comprehensive Chromosome Screening Methodology in Human Blastocysts. Molecular Human Reproduction. PMID 29186554 DOI: 10.1093/Molehr/Gax060  0.344
2017 Tao X, Landis JN, Krisher RL, Duncan FE, Silva E, Lonczak A, Scott RT, Zhan Y, Chu T, Scott RT, Treff NR. Mitochondrial DNA content is associated with ploidy status, maternal age, and oocyte maturation methods in mouse blastocysts. Journal of Assisted Reproduction and Genetics. PMID 29063991 DOI: 10.1007/S10815-017-1070-8  0.346
2017 Capalbo A, Treff N, Cimadomo D, Tao X, Ferrero S, Vaiarelli A, Colamaria S, Maggiulli R, Orlando G, Scarica C, Scott R, Ubaldi FM, Rienzi L. Abnormally fertilized oocytes can result in healthy live births: improved genetic technologies for preimplantation genetic testing can be used to rescue viable embryos in in vitro fertilization cycles. Fertility and Sterility. PMID 28923286 DOI: 10.1016/J.Fertnstert.2017.08.004  0.319
2017 Goodrich D, Xing T, Tao X, Lonczak A, Zhan Y, Landis J, Zimmerman R, Scott RT, Treff NR. Evaluation of comprehensive chromosome screening platforms for the detection of mosaic segmental aneuploidy. Journal of Assisted Reproduction and Genetics. PMID 28577183 DOI: 10.1097/Ogx.0000000000000647  0.352
2017 Treff NR, Zimmerman RS. Advances in Preimplantation Genetic Testing for Monogenic Disease and Aneuploidy. Annual Review of Genomics and Human Genetics. PMID 28498723 DOI: 10.1146/Annurev-Genom-091416-035508  0.332
2017 Marin D, Wang Y, Tao X, Scott RT, Treff NR. Comprehensive chromosome screening and gene expression analysis from the same biopsy in human preimplantation embryos. Molecular Human Reproduction. 1-9. PMID 28369516 DOI: 10.1093/Molehr/Gax014  0.394
2017 Marin D, Scott RT, Treff NR. Preimplantation embryonic mosaicism: origin, consequences and the reliability of comprehensive chromosome screening. Current Opinion in Obstetrics & Gynecology. PMID 28266934 DOI: 10.1097/Gco.0000000000000358  0.384
2017 Chia G, Agudo J, Treff N, Sauer MV, Billing D, Brown BD, Baer R, Egli D. Genomic instability during reprogramming by nuclear transfer is DNA replication dependent. Nature Cell Biology. PMID 28263958 DOI: 10.1038/Ncb3485  0.363
2017 Morin SJ, Treff NR, Tao X, Scott RT, Franasiak JM, Juneau CR, Maguire M, Scott RT. Combination of uterine natural killer cell immunoglobulin receptor haplotype and trophoblastic HLA-C ligand influences the risk of pregnancy loss: a retrospective cohort analysis of direct embryo genotyping data from euploid transfers. Fertility and Sterility. PMID 28069185 DOI: 10.1016/J.Fertnstert.2016.12.004  0.313
2017 Tao X, Franasiak JM, Zhan Y, Scott RT, Rajchel J, Bedard J, Newby R, Treff NR, Chu T. Characterizing the endometrial microbiome by analyzing the ultra-low bacteria from embryo transfer catheter tips in IVF cycles: next generation sequencing (NGS) analysis of the 16S ribosomal gene Human Microbiome Journal. 3: 15-21. DOI: 10.1016/J.Humic.2017.01.004  0.311
2017 Tiegs AW, Morin SJ, Forman EJ, Franasiak JM, Zimmerman RS, Zhan Y, Juneau CR, Neal SA, Treff N, Scott RT. Only segmental or mosaic aneuploid embryos available for transfer: a rare phenomenon in preimplantation genetic screening (PGS) cycles using targeted next generation sequencing (NGS) Fertility and Sterility. 108. DOI: 10.1016/J.Fertnstert.2017.07.814  0.328
2017 Marin D, Sun L, Scott RT, Treff N. Increased implantation rates with targeted next generation sequencing (TNGS) compared to QPCR-based comprehensive chromosome screening Fertility and Sterility. 108. DOI: 10.1016/J.Fertnstert.2017.07.806  0.324
2017 Tao X, Zhan Y, Scott RT, Bedard JL, Treff N. Tracking implanted embryos using cell-free fetal DNA from maternal circulation at 9 weeks gestation by targeted NGS Fertility and Sterility. 108. DOI: 10.1016/J.Fertnstert.2017.07.279  0.309
2017 Marin D, Zimmerman RS, Jalas C, Zhan Y, Lonczak A, Scott RT, Treff N. The perks of going targeted: sample contamination, DNA fingerprinting and chromosomal mosaicism accurately predicted by targeted NGS-based comprehensive chromosome screening Fertility and Sterility. 108. DOI: 10.1016/J.Fertnstert.2017.07.273  0.326
2017 Marin D, Zimmerman RS, Tao X, Zhan Y, Scott RT, Treff N. The challenge of polyploidy and comprehensive chromosome screening: validation of a targeted next generation sequencing (TNGS) platform for detection of triploidy in human blastocysts Fertility and Sterility. 108. DOI: 10.1016/J.Fertnstert.2017.07.083  0.349
2017 Eccles JM, Iturriaga A, Garnsey HM, Landis JN, Zhan Y, Scott RT, Treff N, Zimmerman RS. Experience with a targeted next generation sequencing (TNGS) platform for comprehensive chromosome screening (CCS) on over 16,000 embryo biopsies Fertility and Sterility. 108. DOI: 10.1016/J.Fertnstert.2017.07.080  0.347
2016 Treff NR, Franasiak JM. Detection of segmental aneuploidy and mosaicism in the human preimplantation embryo: technical considerations and limitations. Fertility and Sterility. PMID 27816233 DOI: 10.1016/J.Fertnstert.2016.09.039  0.379
2016 Capalbo A, Ubaldi FM, Rienzi L, Scott R, Treff N. Detecting mosaicism in trophectoderm biopsies: current challenges and future possibilities. Human Reproduction (Oxford, England). PMID 27738115 DOI: 10.1093/Humrep/Dew250  0.346
2016 Franasiak JM, Olcha M, Shastri S, Molinaro TA, Congdon H, Treff NR, Scott RT. Embryonic aneuploidy does not differ among genetic ancestry according to continental origin as determined by ancestry informative markers. Human Reproduction (Oxford, England). PMID 27591228 DOI: 10.1093/Humrep/Dew195  0.314
2016 Goodrich D, Tao X, Bohrer C, Lonczak A, Xing T, Zimmerman R, Zhan Y, Scott RT, Treff NR. A randomized and blinded comparison of qPCR and NGS-based detection of aneuploidy in a cell line mixture model of blastocyst biopsy mosaicism. Journal of Assisted Reproduction and Genetics. PMID 27497716 DOI: 10.1007/S10815-016-0784-3  0.364
2016 Treff NR, Thompson K, Rafizadeh M, Chow M, Morrison L, Tao X, Garnsey H, Reda CV, Metzgar TL, Neal S, Jalas C, Scott RT, Forman EJ. SNP array-based analyses of unbalanced embryos as a reference to distinguish between balanced translocation carrier and normal blastocysts. Journal of Assisted Reproduction and Genetics. PMID 27241531 DOI: 10.1007/S10815-016-0734-0  0.381
2016 Treff NR, Krisher RL, Tao X, Garnsey H, Bohrer C, Silva E, Landis J, Taylor D, Scott RT, Woodruff TK, Duncan FE. Next Generation Sequencing Based Comprehensive Chromosome Screening in Mouse Polar Bodies, Oocytes, and Embryos. Biology of Reproduction. PMID 26911429 DOI: 10.1095/Biolreprod.115.135483  0.386
2016 Juneau C, Franasiak J, Treff N. Challenges facing contemporary preimplantation genetic screening Current Opinion in Obstetrics and Gynecology. 28: 151-157. DOI: 10.1097/Gco.0000000000000270  0.348
2016 Franasiak JM, Tao X, Zhan Y, Chu TC, Treff NR, Scott RT. Characterizing the microbiome at embryo transfer: next generation sequencing of the 16S ribosomal gene Reproductive Biomedicine Online. 33. DOI: 10.1016/J.Rbmo.2016.06.014  0.31
2016 Horne J, Franasiak JM, Juneau CR, Morin SJ, Forman EJ, Treff NR, Scott RT. Paternal age does not impact aneuploidy rates as determined by comprehensive chromosome screening (CCS) in donor oocyte cycles Fertility and Sterility. 106. DOI: 10.1016/J.Fertnstert.2016.07.1059  0.336
2016 Treff N, Wang Y, Tao X, Scott R. Comprehensive chromosome screening and gene expression analysis from the same biopsy Fertility and Sterility. 106: e22. DOI: 10.1016/J.Fertnstert.2016.07.074  0.351
2015 Kort DH, Chia G, Treff NR, Tanaka AJ, Xing T, Vensand LB, Micucci S, Prosser R, Lobo RA, Sauer MV, Egli D. Human embryos commonly form abnormal nuclei during development: a mechanism of DNA damage, embryonic aneuploidy, and developmental arrest. Human Reproduction (Oxford, England). PMID 26621855 DOI: 10.1093/Humrep/Dev281  0.38
2015 Zimmerman RS, Jalas C, Tao X, Fedick AM, Kim JG, Pepe RJ, Northrop LE, Scott RT, Treff NR. Development and validation of concurrent preimplantation genetic diagnosis for single gene disorders and comprehensive chromosomal aneuploidy screening without whole-genome amplification. Fertility and Sterility. PMID 26602983 DOI: 10.1016/J.Fertnstert.2015.10.003  0.35
2015 Franasiak JM, Werner MD, Juneau CR, Tao X, Landis J, Zhan Y, Treff NR, Scott RT. Endometrial microbiome at the time of embryo transfer: next-generation sequencing of the 16S ribosomal subunit. Journal of Assisted Reproduction and Genetics. PMID 26547201 DOI: 10.1007/S10815-015-0614-Z  0.312
2015 Fellmeth JE, Gordon D, Robins CE, Scott RT, Treff NR, Schindler K. Expression and characterization of three Aurora kinase C splice variants found in human oocytes. Molecular Human Reproduction. PMID 25995441 DOI: 10.1093/Molehr/Gav026  0.373
2015 Werner MD, Scott RT, Treff NR. 24-chromosome PCR for aneuploidy screening. Current Opinion in Obstetrics & Gynecology. 27: 201-5. PMID 25699477 DOI: 10.1097/Gco.0000000000000167  0.342
2015 Gardner DK, Meseguer M, Rubio C, Treff NR. Diagnosis of human preimplantation embryo viability. Human Reproduction Update. PMID 25567750 DOI: 10.1093/Humupd/Dmu064  0.388
2015 Capalbo A, Treff NR, Cimadomo D, Tao X, Upham K, Ubaldi FM, Rienzi L, Scott RT. Comparison of array comparative genomic hybridization and quantitative real-time PCR-based aneuploidy screening of blastocyst biopsies. European Journal of Human Genetics : Ejhg. 23: 901-6. PMID 25351780 DOI: 10.1038/Ejhg.2014.222  0.391
2015 Treff NR, Thompson K, Rafizadeh M, Tao X, Garnsey H, Reda CV, Metzgar T, Forman E, Scott RT. First validated method for distinguishing normal from balanced translocation carrier embryos Fertility and Sterility. 104. DOI: 10.1016/J.Fertnstert.2015.07.895  0.318
2015 Goodrich D, Tao X, Bohrer C, Bedard J, Landis JN, Scott RT, Treff NR. Evaluation of Next Generation Sequencing (NGS) based comprehensive chromosome screening (CCS) sensitivity to mosaicism Fertility and Sterility. 104. DOI: 10.1016/J.Fertnstert.2015.07.880  0.328
2015 Treff N, Krisher R, Tao X, Garnsey H, Bohrer C, Silva E, Landis J, Scott R, Woodruff T, Duncan F. Similar levels of premature separation of sister chromatids in the mouse and human oocyte revealed by Next Generation Sequencing Fertility and Sterility. 104: e198. DOI: 10.1016/J.Fertnstert.2015.07.614  0.301
2015 Werner MD, Franasiak JM, Hong KH, Juneau CR, Tao X, Landis J, Upham KM, Treff NR, Scott RT. A prospective, blinded, non-selection study to determine the predictive value of ploidy results using a novel method of targeted amplification based Next generation sequencing (NGS) for comprehensive chromosome screening (CCS) Fertility and Sterility. 104. DOI: 10.1016/J.Fertnstert.2015.07.040  0.322
2014 Werner MD, Leondires MP, Schoolcraft WB, Miller BT, Copperman AB, Robins ED, Arredondo F, Hickman TN, Gutmann J, Schillings WJ, Levy B, Taylor D, Treff NR, Scott RT. Clinically recognizable error rate after the transfer of comprehensive chromosomal screened euploid embryos is low. Fertility and Sterility. 102: 1613-8. PMID 25439802 DOI: 10.1016/J.Fertnstert.2014.09.011  0.334
2014 Franasiak JM, Forman EJ, Hong KH, Werner MD, Upham KM, Treff NR, Scott RT. Aneuploidy across individual chromosomes at the embryonic level in trophectoderm biopsies: changes with patient age and chromosome structure. Journal of Assisted Reproduction and Genetics. 31: 1501-9. PMID 25241130 DOI: 10.1007/S10815-014-0333-X  0.322
2014 Scott RT, Su J, Tao X, Forman EJ, Hong KH, Taylor D, Treff NR. Trophectoderm DNA fingerprinting by quantitative real-time PCR successfully distinguishes sibling human embryos. Journal of Assisted Reproduction and Genetics. 31: 1421-5. PMID 25129376 DOI: 10.1007/S10815-014-0315-Z  0.326
2014 Salvaggio CN, Forman EJ, Garnsey HM, Treff NR, Scott RT. Polar body based aneuploidy screening is poorly predictive of embryo ploidy and reproductive potential. Journal of Assisted Reproduction and Genetics. 31: 1221-6. PMID 25106935 DOI: 10.1007/S10815-014-0293-1  0.315
2014 Gueye NA, Jalas C, Tao X, Taylor D, Scott RT, Treff NR. Improved sensitivity to detect recombination using qPCR for Dyskeratosis Congenita PGD. Journal of Assisted Reproduction and Genetics. 31: 1227-30. PMID 25099625 DOI: 10.1007/S10815-014-0298-9  0.341
2014 Fedick AM, Eckert K, Thompson K, Forman EJ, Devkota B, Treff NR, Taylor D, Scott RT. Lack of association of KATNAL1 gene sequence variants and azoospermia in humans. Journal of Assisted Reproduction and Genetics. 31: 1065-71. PMID 24913027 DOI: 10.1007/S10815-014-0269-1  0.308
2014 Chung YG, Eum JH, Lee JE, Shim SH, Sepilian V, Hong SW, Lee Y, Treff NR, Choi YH, Kimbrel EA, Dittman RE, Lanza R, Lee DR. Human somatic cell nuclear transfer using adult cells. Cell Stem Cell. 14: 777-80. PMID 24746675 DOI: 10.1016/J.Stem.2014.03.015  0.318
2014 Franasiak JM, Forman EJ, Hong KH, Werner MD, Upham KM, Treff NR, Scott RT. The nature of aneuploidy with increasing age of the female partner: a review of 15,169 consecutive trophectoderm biopsies evaluated with comprehensive chromosomal screening. Fertility and Sterility. 101: 656-663.e1. PMID 24355045 DOI: 10.1016/J.Fertnstert.2013.11.004  0.304
2014 Gueye NA, Devkota B, Taylor D, Pfundt R, Scott RT, Treff NR. Uniparental disomy in the human blastocyst is exceedingly rare. Fertility and Sterility. 101: 232-6. PMID 24083874 DOI: 10.1016/J.Fertnstert.2013.08.051  0.314
2014 Tao X, Jalas C, Fedick A, Bohrer C, Garnsey H, Kloskowski S, Gabriele D, Levy B, Scott RT, Treff NR. Rapid and concurrent comprehensive chromosome screening (CCS) and single gene disorder (SGD) PGD Fertility and Sterility. 102. DOI: 10.1016/J.Fertnstert.2014.07.616  0.332
2014 Treff NR, Tao X, Jalas C, Levy B, Scott RT. PGD for micro-deletions and -duplications combined with 24-chromosome aneuploidy screening Fertility and Sterility. 102. DOI: 10.1016/J.Fertnstert.2014.07.327  0.333
2014 Treff N, Tao X, Garnsey H, Bohrer C, Taylor D, Scott R, Woodruff T, Duncan F. Use of whole genome sequencing to identify chromosome-specific egg aneuploidy in a mouse model of natural reproductive aging Fertility and Sterility. 102: e330. DOI: 10.1016/J.Fertnstert.2014.07.1116  0.325
2014 Werner MD, Scott K, Bohrer C, Gabriele D, Tao X, Hong KH, Taylor D, Treff NR, Scott RT. The accuracy of blastocoel fluid comprehensive chromosomal screening (CCS) is dependent on amplification yield and sequencing depth when using nextgen sequencing Fertility and Sterility. 102. DOI: 10.1016/J.Fertnstert.2014.07.1048  0.301
2013 Scott RT, Upham KM, Forman EJ, Zhao T, Treff NR. Cleavage-stage biopsy significantly impairs human embryonic implantation potential while blastocyst biopsy does not: a randomized and paired clinical trial. Fertility and Sterility. 100: 624-30. PMID 23773313 DOI: 10.1016/J.Fertnstert.2013.04.039  0.309
2013 Scott RT, Upham KM, Forman EJ, Hong KH, Scott KL, Taylor D, Tao X, Treff NR. Blastocyst biopsy with comprehensive chromosome screening and fresh embryo transfer significantly increases in vitro fertilization implantation and delivery rates: a randomized controlled trial. Fertility and Sterility. 100: 697-703. PMID 23731996 DOI: 10.1016/J.Fertnstert.2013.04.035  0.361
2013 Forman EJ, Upham KM, Cheng M, Zhao T, Hong KH, Treff NR, Scott RT. Comprehensive chromosome screening alters traditional morphology-based embryo selection: a prospective study of 100 consecutive cycles of planned fresh euploid blastocyst transfer. Fertility and Sterility. 100: 718-24. PMID 23725804 DOI: 10.1016/J.Fertnstert.2013.04.043  0.364
2013 Treff NR, Forman EJ, Katz-Jaffe MG, Schoolcraft WB, Levy B, Scott RT. Incidental identification of balanced translocation carrier patients through comprehensive chromosome screening of IVF-derived blastocysts. Journal of Assisted Reproduction and Genetics. 30: 787-91. PMID 23722938 DOI: 10.1007/S10815-013-0008-Z  0.375
2013 Forman EJ, Hong KH, Ferry KM, Tao X, Taylor D, Levy B, Treff NR, Scott RT. In vitro fertilization with single euploid blastocyst transfer: a randomized controlled trial. Fertility and Sterility. 100: 100-7.e1. PMID 23548942 DOI: 10.1016/J.Fertnstert.2013.02.056  0.335
2013 Paull D, Emmanuele V, Weiss KA, Treff N, Stewart L, Hua H, Zimmer M, Kahler DJ, Goland RS, Noggle SA, Prosser R, Hirano M, Sauer MV, Egli D. Nuclear genome transfer in human oocytes eliminates mitochondrial DNA variants. Nature. 493: 632-7. PMID 23254936 DOI: 10.1038/Nature11800  0.338
2013 Treff NR, Scott RT. Four-hour quantitative real-time polymerase chain reaction-based comprehensive chromosome screening and accumulating evidence of accuracy, safety, predictive value, and clinical efficacy. Fertility and Sterility. 99: 1049-53. PMID 23206734 DOI: 10.1016/J.Fertnstert.2012.11.007  0.341
2013 Forman EJ, Treff NR, Stevens JM, Garnsey HM, Katz-Jaffe MG, Scott RT, Schoolcraft WB. Embryos whose polar bodies contain isolated reciprocal chromosome aneuploidy are almost always euploid. Human Reproduction (Oxford, England). 28: 502-8. PMID 23169867 DOI: 10.1093/Humrep/Des393  0.342
2013 Treff N, Tao X, Taylor D, Hong K, Forman E, Scott R. Development and validation of a next-generation sequencing (NGS)-based 24-chromosome aneuploidy screening system Fertility and Sterility. 100: S82. DOI: 10.1016/J.Fertnstert.2013.07.1955  0.34
2013 Garnsey HM, Tao X, Taylor D, Pfau SJ, Duncan F, Treff NR. Development of a SNP array based methodology for mouse single cell comprehensive chromosomal aneuploidy screening Fertility and Sterility. 100. DOI: 10.1016/J.Fertnstert.2013.07.1598  0.353
2013 Forman EJ, Salvaggio CN, Garnsey HM, Treff NR, Scott RT. Polar body (PB) based aneuploidy screening is significantly less predictive of the reproductive potential of embryos than embryo biopsy based techniques Fertility and Sterility. 100. DOI: 10.1016/J.Fertnstert.2013.07.1353  0.314
2013 Capalbo A, Ubaldi FM, Rienzi L, Tao X, Treff NR, Scott RT. Comparison of quantitative real-time (q)PCR and array comparative genomic hybridization (aCGH) based 24 chromosome aneuploidy screening in human blastocysts Fertility and Sterility. 100. DOI: 10.1016/J.Fertnstert.2013.07.128  0.342
2012 Treff NR. Genome-wide analysis of human preimplantation aneuploidy. Seminars in Reproductive Medicine. 30: 283-8. PMID 22723009 DOI: 10.1055/S-0032-1313907  0.352
2012 Forman EJ, Li X, Ferry KM, Scott K, Treff NR, Scott RT. Oocyte vitrification does not increase the risk of embryonic aneuploidy or diminish the implantation potential of blastocysts created after intracytoplasmic sperm injection: a novel, paired randomized controlled trial using DNA fingerprinting. Fertility and Sterility. 98: 644-9. PMID 22608316 DOI: 10.1016/J.Fertnstert.2012.04.028  0.324
2012 Forman EJ, Hong KH, Treff NR, Scott RT. Comprehensive chromosome screening and embryo selection: moving toward single euploid blastocyst transfer. Seminars in Reproductive Medicine. 30: 236-42. PMID 22585635 DOI: 10.1055/S-0032-1311526  0.371
2012 Scott RT, Treff NR, Stevens J, Forman EJ, Hong KH, Katz-Jaffe MG, Schoolcraft WB. Delivery of a chromosomally normal child from an oocyte with reciprocal aneuploid polar bodies. Journal of Assisted Reproduction and Genetics. 29: 533-7. PMID 22460080 DOI: 10.1007/S10815-012-9746-6  0.311
2012 Treff NR, Scott RT. Methods for comprehensive chromosome screening of oocytes and embryos: capabilities, limitations, and evidence of validity. Journal of Assisted Reproduction and Genetics. 29: 381-90. PMID 22415246 DOI: 10.1007/S10815-012-9727-9  0.376
2012 Forman EJ, Tao X, Ferry KM, Taylor D, Treff NR, Scott RT. Single embryo transfer with comprehensive chromosome screening Results in improved ongoing pregnancy rates and decreased miscarriage rates Human Reproduction. 27: 1217-1222. PMID 22343551 DOI: 10.1093/Humrep/Des020  0.318
2012 Treff NR, Tao X, Ferry KM, Su J, Taylor D, Scott RT. Development and validation of an accurate quantitative real-time polymerase chain reaction-based assay for human blastocyst comprehensive chromosomal aneuploidy screening. Fertility and Sterility. 97: 819-24. PMID 22342859 DOI: 10.1016/J.Fertnstert.2012.01.115  0.333
2012 Scott RT, Ferry K, Su J, Tao X, Scott K, Treff NR. Comprehensive chromosome screening is highly predictive of the reproductive potential of human embryos: a prospective, blinded, nonselection study. Fertility and Sterility. 97: 870-5. PMID 22305103 DOI: 10.1016/J.Fertnstert.2012.01.104  0.357
2012 Fedick A, Su J, Treff NR. Development of TaqMan allelic discrimination based genotyping of large DNA deletions. Genomics. 99: 127-31. PMID 22281206 DOI: 10.1016/J.Ygeno.2012.01.003  0.307
2012 Tao X, Scott RT, Su J, Forman E, Taylor D, Treff N. Quantitative real-time (q)pcr based embryonic DNA fingerprinting successfully distinguishes sibling human embryos: a practical tool for biomarker development Fertility and Sterility. 98. DOI: 10.1016/J.Fertnstert.2012.07.516  0.331
2012 Forman EJ, Ferry K, Katz-Jaffe M, Schoolcraft W, Treff N, Scott R. Trophectoderm (TE) biopsy, blastocyst vitrification, and simultaneous single gene disorder (SGD) and comprehensive chromosome screening (CCS) results in excellent ongoing pregnancy rates Fertility and Sterility. 98. DOI: 10.1016/J.Fertnstert.2012.07.495  0.357
2012 Pepe R, Tao X, Su J, Stevens J, Treff N, Scott R. Development of a 4 hour protocol for simultaneous single gene disorder (SGD) and comprehensive chromosomal aneuploidy screening (CCS) from a single trophectoderm (TE) biopsy Fertility and Sterility. 98. DOI: 10.1016/J.Fertnstert.2012.07.493  0.346
2012 Forman EJ, Su J, Taylor D, Devkota B, Treff N, Scott R. Oocyte vitrification does not result in a decrement in mitochondrial DNA (mtDNA) copy number in resulting embryos: a paired randomized controlled trial (RCT) Fertility and Sterility. 98. DOI: 10.1016/J.Fertnstert.2012.07.325  0.302
2012 Forman EJ, Stevens JM, Katz-Jaffe M, Schoolcraft W, Treff N, Scott R. Embryos whose polar bodies had a reciprocal chromosomal abnormality are almost always euploid: a result of correction of premature separation of sister chromatids (PSSC) Fertility and Sterility. 98. DOI: 10.1016/J.Fertnstert.2012.07.215  0.341
2012 Hong K, Taylor D, Forman E, Tao X, Treff N, Scott R. Development of a novel next-gen sequencing (NGS) methodology for accurate characterization of genome-wide mitochondrial heteroplasmy in human embryos Fertility and Sterility. 98: S58-S59. DOI: 10.1016/J.Fertnstert.2012.07.208  0.313
2012 Forman EJ, Hong KH, Ferry KM, Tao X, Treff NR, Scott RT. Blastocyst euploid selective transfer (BEST): an RCT of comprehensive chromosome screening-single embryo transfer (CCS-SET) vs double embryo transfer (DET)-equivalent pregnancy rates, eliminates twins Fertility and Sterility. 98. DOI: 10.1016/J.Fertnstert.2012.07.177  0.342
2012 Stevens J, Rawlins M, Janesch A, Treff N, Schoolcraft WB, Katz-Jaffe MG. Time lapse observation of embryo development identifies later stage morphology based parameters associated with blastocyst quality but not chromosome constitution Fertility and Sterility. 98. DOI: 10.1016/J.Fertnstert.2012.07.112  0.33
2012 Mitchell S, Linden M, Young D, Treff N, Schoolcraft W, Katz-Jaffe M. The incidence of chromosome errors differs at the preimplantation stage from that observed later in pregnancy Fertility and Sterility. 98. DOI: 10.1016/J.Fertnstert.2012.07.039  0.315
2011 Schoolcraft WB, Treff NR, Stevens JM, Ferry K, Katz-Jaffe M, Scott RT. Live birth outcome with trophectoderm biopsy, blastocyst vitrification, and single-nucleotide polymorphism microarray-based comprehensive chromosome screening in infertile patients. Fertility and Sterility. 96: 638-40. PMID 21782169 DOI: 10.1016/J.Fertnstert.2011.06.049  0.371
2011 Treff NR, Su J, Taylor D, Scott RT. Telomere DNA deficiency is associated with development of human embryonic aneuploidy. Plos Genetics. 7: e1002161. PMID 21738493 DOI: 10.1371/Journal.Pgen.1002161  0.385
2011 Treff NR, Tao X, Schillings WJ, Bergh PA, Scott RT, Levy B. Use of single nucleotide polymorphism microarrays to distinguish between balanced and normal chromosomes in embryos from a translocation carrier. Fertility and Sterility. 96: e58-65. PMID 21575938 DOI: 10.1016/J.Fertnstert.2011.04.038  0.369
2011 Treff NR, Tao X, Su J, Lonczak A, Northrop LE, Ruiz AA, Scott RT. Tracking embryo implantation using cell-free fetal DNA enriched from maternal circulation at 9 weeks gestation. Molecular Human Reproduction. 17: 434-8. PMID 21357209 DOI: 10.1093/Molehr/Gar016  0.348
2011 Treff NR, Su J, Tao X, Northrop LE, Scott RT. Single-cell whole-genome amplification technique impacts the accuracy of SNP microarray-based genotyping and copy number analyses. Molecular Human Reproduction. 17: 335-43. PMID 21177337 DOI: 10.1093/Molehr/Gaq103  0.316
2011 Kahan B, Magliocca J, Merriam F, Treff N, Budde M, Nelson J, Browning V, Ziehr B, Odorico J. Elimination of tumorigenic stem cells from differentiated progeny and selection of definitive endoderm reveals a Pdx1+ foregut endoderm stem cell lineage. Stem Cell Research. 6: 143-57. PMID 21130058 DOI: 10.1016/J.Scr.2010.10.003  0.311
2011 Treff NR, Northrop LE, Kasabwala K, Su J, Levy B, Scott RT. Single nucleotide polymorphism microarray-based concurrent screening of 24-chromosome aneuploidy and unbalanced translocations in preimplantation human embryos. Fertility and Sterility. 95: 1606-12.e1-2. PMID 21122835 DOI: 10.1016/J.Fertnstert.2010.11.004  0.397
2011 Forman E, Treff N, Tao X, Ferry K, Taylor D, Scott R. Comprehensive chromosome screening (CCS) results in significantly higher pregnancy rates and lower loss rates from single embryo transfer (SET) in a poor prognosis population Fertility and Sterility. 96: S17. DOI: 10.1016/J.Fertnstert.2011.07.076  0.343
2011 Treff NR, Ferry KM, Zhao T, Su J, Forman EJ, Scott RT. Cleavage stage embryo biopsy significantly impairs embryonic reproductive potential while blastocyst biopsy does not: a novel paired analysis of cotransferred biopsied and non-biopsied sibling embryos Fertility and Sterility. 96. DOI: 10.1016/J.Fertnstert.2011.07.015  0.31
2011 Forman EJ, Benson MR, Treff NR, Scott RT. Clinical Experience Using SNP-based Comprehensive Chromosomal Screening in Patients with Recurrent Pregnancy Loss Fertility and Sterility. 95. DOI: 10.1016/J.Fertnstert.2011.01.079  0.323
2010 Treff NR, Levy B, Su J, Northrop LE, Tao X, Scott RT. SNP microarray-based 24 chromosome aneuploidy screening is significantly more consistent than FISH. Molecular Human Reproduction. 16: 583-9. PMID 20484246 DOI: 10.1093/Molehr/Gaq039  0.391
2010 Northrop LE, Treff NR, Levy B, Scott RT. SNP microarray-based 24 chromosome aneuploidy screening demonstrates that cleavage-stage FISH poorly predicts aneuploidy in embryos that develop to morphologically normal blastocysts. Molecular Human Reproduction. 16: 590-600. PMID 20479065 DOI: 10.1093/Molehr/Gaq037  0.376
2010 Scott RT, Treff NR. Assessing the reproductive competence of individual embryos: a proposal for the validation of new "-omics" technologies. Fertility and Sterility. 94: 791-4. PMID 20460188 DOI: 10.1016/J.Fertnstert.2010.03.041  0.3
2010 Treff NR, Su J, Tao X, Levy B, Scott RT. Accurate single cell 24 chromosome aneuploidy screening using whole genome amplification and single nucleotide polymorphism microarrays. Fertility and Sterility. 94: 2017-21. PMID 20188357 DOI: 10.1016/J.Fertnstert.2010.01.052  0.349
2010 Treff NR, Su J, Kasabwala N, Tao X, Miller KA, Scott RT. Robust embryo identification using first polar body single nucleotide polymorphism microarray-based DNA fingerprinting. Fertility and Sterility. 93: 2453-5. PMID 19896651 DOI: 10.1016/J.Fertnstert.2009.08.070  0.321
2010 Treff NR, Su J, Tao X, Miller KA, Levy B, Scott RT. A novel single-cell DNA fingerprinting method successfully distinguishes sibling human embryos. Fertility and Sterility. 94: 477-84. PMID 19394599 DOI: 10.1016/J.Fertnstert.2009.03.067  0.378
2010 Treff NR, Su J, Taylor D, Scott RT. Aneuploid Human Oocytes and Embryos Possess Significantly Reduced Quantities of Telomere DNA. Biology of Reproduction. 83: 10-10. DOI: 10.1093/Biolreprod/83.S1.10  0.34
2010 Taylor D, Pike J, Kasabwala K, Northrop L, Treff N, Scott R. A genome-wide association scan identifies several maternal susceptbility loci for embryo aneuploidy Fertility and Sterility. 94: S183. DOI: 10.1016/J.Fertnstert.2010.07.713  0.341
2010 Loper R, Treff NR, Parks JC, Scott RT, Schoolcraft WB, Katz-Jaffe MG. Alterations of mitotic checkpoint genes play a role in embryonic chromosome mosaicism Fertility and Sterility. 94. DOI: 10.1016/J.Fertnstert.2010.07.594  0.329
2010 Northrop L, Treff N, Taylor D, Scott R. Premature separation of sister chromatids (PSSC) associated chromosome recombination rates are not significantly different from normally segregated chromosomes Fertility and Sterility. 94: S137. DOI: 10.1016/J.Fertnstert.2010.07.552  0.319
2010 Treff N, Tao X, Taylor D, Ferry K, Scott R. First pregnancies after blastocyst biopsy and rapid 24 chromosome aneuploidy screening allowing a fresh transfer within four hours of biopsy Fertility and Sterility. 94: S126-S127. DOI: 10.1016/J.Fertnstert.2010.07.511  0.351
2010 Tao X, Campos J, Ferry KM, Levy B, Treff NR, Scott RT. First clinical application of simultaneous preimplantation mitochondrial DNA mutation load and 24 chromosome aneuploidy screening Fertility and Sterility. 94. DOI: 10.1016/J.Fertnstert.2010.07.510  0.327
2010 Scott K, Taylor D, Ferry K, Treff N, Scott R. Characterizing the relationship between morphologic embryonic development and ploidy status as assessed by 24 chromosome microarray PGD Fertility and Sterility. 94: S122-S123. DOI: 10.1016/J.Fertnstert.2010.07.498  0.323
2010 Treff N, Su J, Lonczak A, Taylor D, Scott R. A subset of the cumulus cell transcriptome is predictive of euploid human oocyte reproductive potential Fertility and Sterility. 94: S34-S35. DOI: 10.1016/J.Fertnstert.2010.07.132  0.314
2010 Schoolcraft WB, Treff NR, Ferry K, Stevens JM, Katz-Jaffe MG, Scott RT. First clinical application of SNP microarray based 24 chromosome aneuploidy screening of human blastocysts Fertility and Sterility. 94. DOI: 10.1016/J.Fertnstert.2010.07.090  0.351
2010 Treff N, Su J, Taylor D, Molinaro T, Scott R. Telomere DNA is significantly reduced in aneuploid human oocytes and embryos Fertility and Sterility. 94: S9. DOI: 10.1016/J.Fertnstert.2010.07.033  0.339
2010 Scott R, Tao X, Taylor D, Ferry K, Treff N. A prospective randomized controlled trial demonstrating significantly increased clinical pregnancy rates following 24 chromosome aneuploidy screening: biopsy and analysis on day 5 with fresh transfer Fertility and Sterility. 94: S2. DOI: 10.1016/J.Fertnstert.2010.07.007  0.333
2009 Chung Y, Bishop CE, Treff NR, Walker SJ, Sandler VM, Becker S, Klimanskaya I, Wun WS, Dunn R, Hall RM, Su J, Lu SJ, Maserati M, Choi YH, Scott R, et al. Reprogramming of human somatic cells using human and animal oocytes. Cloning and Stem Cells. 11: 213-23. PMID 19186982 DOI: 10.1089/Clo.2009.0004  0.38
2009 Treff N, Tao X, Su J, Northrop L, Kamani M, Bergh P, Miller K, Levy B, Scott R. SNP Microarray Based Concurrent Screening of 24 Chromosome Aneuploidy, Unbalanced Translocations, and Single Gene Disorders in Human Embryos: First Application of Comprehensive Triple Factor PGD. Biology of Reproduction. 81: 188-188. DOI: 10.1093/Biolreprod/81.S1.188  0.374
2009 Treff N, Tao X, Su J, Taylor D, Miller K, Scott R. Four hour 24 chromosome aneuploidy screening using high throughput PCR SNP allele ratio analyses Fertility and Sterility. 92: S49-S50. DOI: 10.1016/J.Fertnstert.2009.07.193  0.332
2009 Treff N, Su J, Tao X, Miller K, Scott R. First IVF babies born after rapid 24 chromosome embryo aneuploidy screening and fresh embryo transfer Fertility and Sterility. 92. DOI: 10.1016/J.Fertnstert.2009.07.190  0.374
2009 Stevens J, McCormick S, Treff NR, Scott RT, Schoolcraft WB, Katz-Jaffe MG. Maternal age related effects on chromosome error in human oocytes Fertility and Sterility. 92. DOI: 10.1016/J.Fertnstert.2009.07.1506  0.308
2009 Treff N, Tao X, Northrop L, Bergh P, Levy B, Scott R. Development and validation of comprehensive triple factor PGD: simultaneous 24 chromosome aneuploidy, translocation derivative, and single gene disorder screening from a single biopsy Fertility and Sterility. 92: S200-S201. DOI: 10.1016/J.Fertnstert.2009.07.1444  0.348
2009 Miller KA, Ferry K, Olivares R, Su J, Treff NR, Scott RT. Efficacy of thaw, trophectoderm biopsy, re-cryopreservation, and pre-implantation genetic screening on previously frozen blastocyst embryos Fertility and Sterility. 92. DOI: 10.1016/J.Fertnstert.2009.07.1389  0.314
2009 Tao X, Lonczak A, Ruiz A, Su J, Treff N, Scott R. Validation of embryo DNA fingerprinting from maternal circulation at 9 weeks gestation Fertility and Sterility. 92. DOI: 10.1016/J.Fertnstert.2009.07.017  0.3
2008 Denis D, Nataraja S, Tran CA, Kagan D, Treff N, Palmer S. Global Gene Expression Analysis in Human Uterine Stromal Cells for the Identification of Novel Targets for Implantation. Biology of Reproduction. 78: 73-74. DOI: 10.1093/Biolreprod/78.S1.73D  0.318
2008 Tao X, Su J, Nahum O, Levy B, Scott RT, Treff NR. Fetal DNA fingerprinting of DNA isolated from the peripheral maternal circulation at 9 gestational weeks allows precise identification of which embryos implanted following multiple embryo transfer Fertility and Sterility. 90. DOI: 10.1016/J.Fertnstert.2008.07.906  0.318
2008 Miller K, Northrop L, Frattarelli J, Su J, Treff N, Scott R. Reanalysis of day 3 fish PGD (fPGD) abnormal embryos which fully blastulated: 24 chromosome microarray PGD (mPGD) demonstrates a high rate of genetic normality and low rate of mosaicism Fertility and Sterility. 90: S48. DOI: 10.1016/J.Fertnstert.2008.07.669  0.33
2008 Treff NR, Su J, Tao X, Frattarelli JL, Miller KA, Scott RT. Characterization of the source of human embryonic aneuploidy using microarray-based 24 chromosome preimplantation genetic diagnosis (mPGD) and aneuploid chromosome fingerprinting Fertility and Sterility. 90. DOI: 10.1016/J.Fertnstert.2008.07.616  0.349
2008 Katz-Jaffe M, McCallie BR, Treff NR, Miller KA, Scott RT, Schoolcraft WB. A novel profile of cumulus cell transcripts is associated with oocyte aneuploidy Fertility and Sterility. 90. DOI: 10.1016/J.Fertnstert.2008.07.613  0.305
2008 Scott RT, Miller KA, Olivares R, Su J, Fratterelli JL, Treff NR. Microarray based 24 chromosome preimplantation genetic diagnosis (mPGD) is highly predictive of the reproductive potential of human embryos: a prospective blinded non-selection trial Fertility and Sterility. 90. DOI: 10.1016/J.Fertnstert.2008.07.438  0.356
2008 Miller KA, Li X, Lambrese K, Su J, Treff N, Scott RT. Blastocyst formation rates in chromosomally normal versus abnormal embryos as analyzed by 24 chromosome microarray-based anueploidy screening (mPGD) Fertility and Sterility. 90. DOI: 10.1016/J.Fertnstert.2008.07.1588  0.364
2008 Scott RT, Miller K, Su J, Kamani M, Levy B, Treff N. Prospective, randomized, blinded, and paired analysis of 24 chromosome microarray PGD (mPGD) vs 9 chromosome fish PGD (fPGD) in dispersed cleavage stage human embryos: mPGD has superior consistency Fertility and Sterility. 90. DOI: 10.1016/J.Fertnstert.2008.07.1012  0.354
2007 Treff NR, Su J, Tao X, Mavrianos J, Scott RT. Single cell whole genome amplification technique significantly impacts the accuracy and precision of microarray based 23 chromosome aneuploidy screening Fertility and Sterility. 88. DOI: 10.1016/J.Fertnstert.2007.07.789  0.349
2007 Treff NR, Su J, Mavrianos J, Bergh PA, Miller KA, Scott RT. Accurate 23 chromosome aneuploidy screening in human blastomeres using single nucleotide polymorphism (SNP) microarrays Fertility and Sterility. 88. DOI: 10.1016/J.Fertnstert.2007.07.025  0.327
2006 Vincent R, Treff N, Budde M, Kastenberg Z, Odorico J. Generation and characterization of novel tetracycline-inducible pancreatic transcription factor-expressing murine embryonic stem cell lines. Stem Cells and Development. 15: 953-62. PMID 17253956 DOI: 10.1089/Scd.2006.15.953  0.317
2006 Xu X, Kahan B, Forgianni A, Jing P, Jacobson L, Browning V, Treff N, Odorico J. Endoderm and pancreatic islet lineage differentiation from human embryonic stem cells. Cloning and Stem Cells. 8: 96-107. PMID 16776601 DOI: 10.1089/Clo.2006.8.96  0.301
2006 Treff NR, Tran CA, Miller KA, Matos DGD, Palmer SS, Scott RT. P-225 : The human blastomere transcriptome and candidate noninvasive molecular prognostics of preimplantation embryo reproductive competence Fertility and Sterility. 86. DOI: 10.1016/J.Fertnstert.2006.07.577  0.31
2005 Dement GA, Treff NR, Magnuson NS, Franceschi V, Reeves R. Dynamic mitochondrial localization of nuclear transcription factor HMGA1. Experimental Cell Research. 307: 388-401. PMID 15893306 DOI: 10.1016/J.Yexcr.2005.04.004  0.736
2004 Treff NR, Dement GA, Adair JE, Britt RL, Nie R, Shima JE, Taylor WE, Reeves R. Human KIT ligand promoter is positively regulated by HMGA1 in breast and ovarian cancer cells. Oncogene. 23: 8557-62. PMID 15378028 DOI: 10.1038/Sj.Onc.1207926  0.733
2004 Treff NR, Pouchnik D, Dement GA, Britt RL, Reeves R. High-mobility group A1a protein regulates Ras/ERK signaling in MCF-7 human breast cancer cells. Oncogene. 23: 777-85. PMID 14737112 DOI: 10.1038/Sj.Onc.1207167  0.732
2001 Pedulla ML, Treff NR, Resar LM, Reeves R. Sequence and analysis of the murine Hmgiy (Hmga1) gene locus. Gene. 271: 51-8. PMID 11410365 DOI: 10.1016/S0378-1119(01)00500-5  0.583
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