Ramon Grima, Ph.D. - Publications

Affiliations: 
2005 Arizona State University, Tempe, AZ, United States 
Area:
General Physics, General Biophysics

73 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Öcal K, Sanguinetti G, Grima R. Model reduction for the Chemical Master Equation: An information-theoretic approach. The Journal of Chemical Physics. 158: 114113. PMID 36948813 DOI: 10.1063/5.0131445  0.32
2021 Sukys A, Grima R. MomentClosure.jl: automated moment closure approximations in Julia. Bioinformatics (Oxford, England). PMID 34170295 DOI: 10.1093/bioinformatics/btab469  0.359
2020 Cao Z, Filatova T, Oyarzún DA, Grima R. A Stochastic Model of Gene Expression with Polymerase Recruitment and Pause Release. Biophysical Journal. PMID 32814062 DOI: 10.1016/J.Bpj.2020.07.020  0.347
2020 Perez-Carrasco R, Beentjes C, Grima R. Effects of cell cycle variability on lineage and population measurements of messenger RNA abundance. Journal of the Royal Society, Interface. 17: 20200360. PMID 32634365 DOI: 10.1098/Rsif.2020.0360  0.322
2020 Jia C, Grima R. Dynamical phase diagram of an auto-regulating gene in fast switching conditions. The Journal of Chemical Physics. 152: 174110. PMID 32384856 DOI: 10.1063/5.0007221  0.365
2020 Beentjes CHL, Perez-Carrasco R, Grima R. Exact solution of stochastic gene expression models with bursting, cell cycle and replication dynamics. Physical Review. E. 101: 032403. PMID 32290003 DOI: 10.1103/Physreve.101.032403  0.417
2020 Holehouse J, Cao Z, Grima R. Stochastic Modeling of Autoregulatory Genetic Feedback Loops: A Review and Comparative Study. Biophysical Journal. PMID 32155410 DOI: 10.1016/J.Bpj.2020.02.016  0.361
2020 Jia C, Grima R. Small protein number effects in stochastic models of autoregulated bursty gene expression. The Journal of Chemical Physics. 152: 084115. PMID 32113345 DOI: 10.1063/1.5144578  0.35
2020 Cao Z, Grima R. Analytical distributions for detailed models of stochastic gene expression in eukaryotic cells. Proceedings of the National Academy of Sciences of the United States of America. PMID 32071224 DOI: 10.1073/Pnas.1910888117  0.361
2020 Holehouse J, Gupta A, Grima R. Steady-state fluctuations of a genetic feedback loop with fluctuating rate parameters using the unified colored noise approximation Journal of Physics A. DOI: 10.1088/1751-8121/Aba4D0  0.316
2020 Öcal K, Grima R, Sanguinetti G. Parameter estimation for biochemical reaction networks using Wasserstein distances Journal of Physics A. 53: 34002. DOI: 10.1088/1751-8121/Ab5877  0.35
2019 Holehouse J, Grima R. Revisiting the Reduction of Stochastic Models of Genetic Feedback Loops with Fast Promoter Switching. Biophysical Journal. PMID 31540707 DOI: 10.1016/J.Bpj.2019.08.021  0.388
2019 Keizer EM, Bastian B, Smith RW, Grima R, Fleck C. Extending the linear-noise approximation to biochemical systems influenced by intrinsic noise and slow lognormally distributed extrinsic noise. Physical Review. E. 99: 052417. PMID 31212540 DOI: 10.1103/Physreve.99.052417  0.354
2019 Cao Z, Grima R. Accuracy of parameter estimation for auto-regulatory transcriptional feedback loops from noisy data. Journal of the Royal Society, Interface. 16: 20180967. PMID 30940028 DOI: 10.1098/Rsif.2018.0967  0.353
2019 Moraki E, Grima R, Painter KJ. A stochastic model of corneal epithelium maintenance and recovery following perturbation Journal of Mathematical Biology. 78: 1245-1276. PMID 30478759 DOI: 10.1007/S00285-018-1308-9  0.385
2018 Cao Z, Grima R. Linear mapping approximation of gene regulatory networks with stochastic dynamics. Nature Communications. 9: 3305. PMID 30120244 DOI: 10.1038/S41467-018-05822-0  0.386
2018 Smith S, Grima R. Spatial Stochastic Intracellular Kinetics: A Review of Modelling Approaches. Bulletin of Mathematical Biology. PMID 29785521 DOI: 10.1007/S11538-018-0443-1  0.435
2018 Smith S, Grima R. Single-cell variability in multicellular organisms. Nature Communications. 9: 345. PMID 29367605 DOI: 10.1038/S41467-017-02710-X  0.348
2017 Schnoerr D, Cseke B, Grima R, Sanguinetti G. Efficient Low-Order Approximation of First-Passage Time Distributions. Physical Review Letters. 119: 210601. PMID 29219406 DOI: 10.1103/Physrevlett.119.210601  0.4
2017 Cianci C, Smith S, Grima R. Capturing Brownian dynamics with an on-lattice model of hard-sphere diffusion. Physical Review. E. 95: 052118. PMID 28618561 DOI: 10.1103/Physreve.95.052118  0.426
2017 Smith S, Cianci C, Grima R. Macromolecular crowding directs the motion of small molecules inside cells. Journal of the Royal Society, Interface. 14. PMID 28615492 DOI: 10.1098/Rsif.2017.0047  0.383
2017 Smith S, Grima R. Fast simulation of Brownian dynamics in a crowded environment. The Journal of Chemical Physics. 146: 024105. PMID 28088138 DOI: 10.1063/1.4973606  0.355
2017 Cianci C, Schnoerr D, Piehler A, Grima R. An alternative route to the system-size expansion Journal of Physics a: Mathematical and Theoretical. 50: 395003. DOI: 10.1088/1751-8121/Aa85Aa  0.394
2017 Schnoerr D, Sanguinetti G, Grima R. Approximation and inference methods for stochastic biochemical kinetics—a tutorial review Journal of Physics a: Mathematical and Theoretical. 50: 093001. DOI: 10.1088/1751-8121/Aa54D9  0.428
2016 Grima R, Leier A. Exact Product Formation Rates for Stochastic Enzyme Kinetics. The Journal of Physical Chemistry. B. PMID 27959536 DOI: 10.1021/Acs.Jpcb.6B08891  0.344
2016 Fröhlich F, Thomas P, Kazeroonian A, Theis FJ, Grima R, Hasenauer J. Inference for Stochastic Chemical Kinetics Using Moment Equations and System Size Expansion. Plos Computational Biology. 12: e1005030. PMID 27447730 DOI: 10.1371/Journal.Pcbi.1005030  0.414
2016 Smith S, Grima R. Breakdown of the reaction-diffusion master equation with nonelementary rates. Physical Review. E. 93: 052135. PMID 27300857 DOI: 10.1103/Physreve.93.052135  0.448
2016 Voliotis M, Thomas P, Grima R, Bowsher CG. Stochastic Simulation of Biomolecular Networks in Dynamic Environments. Plos Computational Biology. 12: e1004923. PMID 27248512 DOI: 10.1371/Journal.Pcbi.1004923  0.383
2016 Schnoerr D, Grima R, Sanguinetti G. Cox process representation and inference for stochastic reaction-diffusion processes. Nature Communications. 7: 11729. PMID 27222432 DOI: 10.1038/Ncomms11729  0.39
2016 Smith S, Cianci C, Grima R. Analytical approximations for spatial stochastic gene expression in single cells and tissues. Journal of the Royal Society, Interface / the Royal Society. 13. PMID 27146686 DOI: 10.1098/Rsif.2015.1051  0.439
2016 Cianci C, Smith S, Grima R. Molecular finite-size effects in stochastic models of equilibrium chemical systems. The Journal of Chemical Physics. 144: 084101. PMID 26931675 DOI: 10.1063/1.4941583  0.471
2016 Smith S, Grima R. Breakdown of the reaction-diffusion master equation with nonelementary rates Physical Review E - Statistical, Nonlinear, and Soft Matter Physics. 93. DOI: 10.1103/PhysRevE.93.052135  0.346
2015 Smith S, Cianci C, Grima R. Model reduction for stochastic chemical systems with abundant species. The Journal of Chemical Physics. 143: 214105. PMID 26646867 DOI: 10.1063/1.4936394  0.388
2015 Schnoerr D, Sanguinetti G, Grima R. Comparison of different moment-closure approximations for stochastic chemical kinetics. The Journal of Chemical Physics. 143: 185101. PMID 26567686 DOI: 10.1063/1.4934990  0.413
2015 Grima R. Linear-noise approximation and the chemical master equation agree up to second-order moments for a class of chemical systems. Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics. 92: 042124. PMID 26565185 DOI: 10.1103/Physreve.92.042124  0.408
2015 Thomas P, Grima R. Approximate probability distributions of the master equation. Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics. 92: 012120. PMID 26274137 DOI: 10.1103/Physreve.92.012120  0.424
2015 Duncan A, Liao S, Vejchodský T, Erban R, Grima R. Noise-induced multistability in chemical systems: Discrete versus continuum modeling. Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics. 91: 042111. PMID 25974443 DOI: 10.1103/Physreve.91.042111  0.4
2014 Schnoerr D, Sanguinetti G, Grima R. Validity conditions for moment closure approximations in stochastic chemical kinetics. The Journal of Chemical Physics. 141: 084103. PMID 25173001 DOI: 10.1063/1.4892838  0.443
2014 Schnoerr D, Sanguinetti G, Grima R. The complex chemical Langevin equation. The Journal of Chemical Physics. 141: 024103. PMID 25027995 DOI: 10.1063/1.4885345  0.436
2014 Middleton AM, Fleck C, Grima R. A continuum approximation to an off-lattice individual-cell based model of cell migration and adhesion. Journal of Theoretical Biology. 359: 220-32. PMID 24972155 DOI: 10.1016/J.Jtbi.2014.06.011  0.369
2014 Thomas P, Popović N, Grima R. Phenotypic switching in gene regulatory networks. Proceedings of the National Academy of Sciences of the United States of America. 111: 6994-9. PMID 24782538 DOI: 10.1073/Pnas.1400049111  0.345
2014 Grima R. Anomalous fluctuation scaling laws in stochastic enzyme kinetics: increase of noise strength with the mean concentration. Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics. 89: 012710. PMID 24580260 DOI: 10.1103/Physreve.89.012710  0.326
2014 Grima R, Walter NG, Schnell S. Single-molecule enzymology à la Michaelis-Menten. The Febs Journal. 281: 518-30. PMID 24289171 DOI: 10.1111/Febs.12663  0.401
2014 Toner DL, Grima R. Effects of bursty protein production on the noisy oscillatory properties of downstream pathways. Scientific Reports. 3: 2438. PMID 23942456 DOI: 10.1038/Srep02438  0.312
2014 Thomas P, Fleck C, Grima R, Popović N. System size expansion using Feynman rules and diagrams Journal of Physics a: Mathematical and Theoretical. 47. DOI: 10.1088/1751-8113/47/45/455007  0.421
2013 Thomas P, Matuschek H, Grima R. How reliable is the linear noise approximation of gene regulatory networks? Bmc Genomics. 14: S5. PMID 24266939 DOI: 10.1186/1471-2164-14-S4-S5  0.374
2013 Thomas P, Straube AV, Timmer J, Fleck C, Grima R. Signatures of nonlinearity in single cell noise-induced oscillations. Journal of Theoretical Biology. 335: 222-34. PMID 23831270 DOI: 10.1016/J.Jtbi.2013.06.021  0.339
2013 Basile R, Grima R, Popović N. A graph-based approach for the approximate solution of the chemical master equation. Bulletin of Mathematical Biology. 75: 1653-96. PMID 23797789 DOI: 10.1007/S11538-013-9864-Z  0.442
2013 Toner DL, Grima R. Molecular noise induces concentration oscillations in chemical systems with stable node steady states. The Journal of Chemical Physics. 138: 055101. PMID 23406149 DOI: 10.1063/1.4788979  0.336
2012 Thomas P, Grima R, Straube AV. Rigorous elimination of fast stochastic variables from the linear noise approximation using projection operators. Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics. 86: 041110. PMID 23214532 DOI: 10.1103/Physreve.86.041110  0.356
2012 Grima R, Kim J. Modelling noise in biochemical reaction networks Iet Systems Biology. 6: 101-101. PMID 23039690 DOI: 10.1049/Iet-Syb.2012.0039  0.371
2012 Grima R, Schmidt DR, Newman TJ. Steady-state fluctuations of a genetic feedback loop: an exact solution. The Journal of Chemical Physics. 137: 035104. PMID 22830733 DOI: 10.1063/1.4736721  0.661
2012 Thomas P, Matuschek H, Grima R. Intrinsic noise analyzer: a software package for the exploration of stochastic biochemical kinetics using the system size expansion. Plos One. 7: e38518. PMID 22723865 DOI: 10.1371/Journal.Pone.0038518  0.446
2012 Thomas P, Straube AV, Grima R. The slow-scale linear noise approximation: an accurate, reduced stochastic description of biochemical networks under timescale separation conditions. Bmc Systems Biology. 6: 39. PMID 22583770 DOI: 10.1186/1752-0509-6-39  0.389
2012 Grima R. A study of the accuracy of moment-closure approximations for stochastic chemical kinetics. The Journal of Chemical Physics. 136: 154105. PMID 22519313 DOI: 10.1063/1.3702848  0.445
2012 Ramaswamy R, González-Segredo N, Sbalzarini IF, Grima R. Discreteness-induced concentration inversion in mesoscopic chemical systems. Nature Communications. 3: 779. PMID 22491327 DOI: 10.1038/Ncomms1775  0.425
2011 Grima R. Construction and accuracy of partial differential equation approximations to the chemical master equation. Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics. 84: 056109. PMID 22181475 DOI: 10.1103/Physreve.84.056109  0.396
2011 Thomas P, Straube AV, Grima R. Communication: limitations of the stochastic quasi-steady-state approximation in open biochemical reaction networks. The Journal of Chemical Physics. 135: 181103. PMID 22088045 DOI: 10.1063/1.3661156  0.44
2011 Grima R, Thomas P, Straube AV. How accurate are the nonlinear chemical Fokker-Planck and chemical Langevin equations? The Journal of Chemical Physics. 135: 084103. PMID 21895155 DOI: 10.1063/1.3625958  0.425
2010 Thomas P, Straube AV, Grima R. Stochastic theory of large-scale enzyme-reaction networks: finite copy number corrections to rate equation models. The Journal of Chemical Physics. 133: 195101. PMID 21090871 DOI: 10.1063/1.3505552  0.435
2010 Grima R. An effective rate equation approach to reaction kinetics in small volumes: Theory and application to biochemical reactions in nonequilibrium steady-state conditions Journal of Chemical Physics. 133: 35101-35101. PMID 20649359 DOI: 10.1063/1.3454685  0.466
2010 Grima R, Yaliraki SN, Barahona M. Crowding-induced anisotropic transport modulates reaction kinetics in nanoscale porous media. The Journal of Physical Chemistry. B. 114: 5380-5. PMID 20369856 DOI: 10.1021/Jp9025865  0.371
2010 Grima R. Intrinsic biochemical noise in crowded intracellular conditions The Journal of Chemical Physics. 132: 185102. DOI: 10.1063/1.3427244  0.443
2009 Grima R. Investigating the robustness of the classical enzyme kinetic equations in small intracellular compartments. Bmc Systems Biology. 3: 101. PMID 19814817 DOI: 10.1186/1752-0509-3-101  0.382
2009 Grima R. Noise-induced breakdown of the Michaelis-Menten equation in steady-state conditions. Physical Review Letters. 102: 218103. PMID 19519139 DOI: 10.1103/PhysRevLett.102.218103  0.329
2008 Grima R, Schnell S. Modelling reaction kinetics inside cells. Essays in Biochemistry. 45: 41-56. PMID 18793122 DOI: 10.1042/Bse0450041  0.391
2008 Grima R. Multiscale modeling of biological pattern formation. Current Topics in Developmental Biology. 81: 435-60. PMID 18023737 DOI: 10.1016/S0070-2153(07)81015-5  0.345
2007 Grima R, Schnell S. A mesoscopic simulation approach for modeling intracellular reactions Journal of Statistical Physics. 128: 139-164. DOI: 10.1007/S10955-006-9202-Z  0.346
2006 Grima R, Schnell S. A systematic investigation of the rate laws valid in intracellular environments Biophysical Chemistry. 124: 1-10. PMID 16781049 DOI: 10.1016/J.Bpc.2006.04.019  0.363
2006 Grima R, Schnell S. How reaction kinetics with time-dependent rate coefficients differs from generalized mass action. Chemphyschem : a European Journal of Chemical Physics and Physical Chemistry. 7: 1422-4. PMID 16755640 DOI: 10.1002/Cphc.200600081  0.371
2005 Grima R. Strong-coupling dynamics of a multicellular chemotactic system. Physical Review Letters. 95: 128103. PMID 16197116 DOI: 10.1103/Physrevlett.95.128103  0.409
2004 Newman TJ, Grima R. Many-body theory of chemotactic cell-cell interactions. Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics. 70: 051916. PMID 15600665 DOI: 10.1103/Physreve.70.051916  0.655
2004 Grima R, Newman TJ. Accurate discretization of advection-diffusion equations. Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics. 70: 036703. PMID 15524671 DOI: 10.1103/Physreve.70.036703  0.656
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