| Year |
Citation |
Score |
| 2023 |
Rogers KJ, Richards PT, Zacharias ZR, Stunz LL, Vijay R, Butler NS, Legge KL, Bishop GA, Maury W. CD40 Signaling in Mice Elicits a Broad Antiviral Response Early during Acute Infection with RNA Viruses. Viruses. 15. PMID 37376652 DOI: 10.3390/v15061353 |
0.444 |
|
| 2021 |
Pack AD, Schwartzhoff PV, Zacharias ZR, Fernandez-Ruiz D, Heath WR, Gurung P, Legge KL, Janse CJ, Butler NS. Hemozoin-mediated inflammasome activation limits long-lived anti-malarial immunity. Cell Reports. 36: 109586. PMID 34433049 DOI: 10.1016/j.celrep.2021.109586 |
0.393 |
|
| 2021 |
Stephens LM, Ross KA, Waldstein KA, Legge KL, McLellan JS, Narasimhan B, Varga SM. Prefusion F-Based Polyanhydride Nanovaccine Induces Both Humoral and Cell-Mediated Immunity Resulting in Long-Lasting Protection against Respiratory Syncytial Virus. Journal of Immunology (Baltimore, Md. : 1950). PMID 33827894 DOI: 10.4049/jimmunol.2100018 |
0.399 |
|
| 2020 |
Lopez CE, Legge KL. Influenza A Virus Vaccination: Immunity, Protection, and Recent Advances Toward A Universal Vaccine. Vaccines. 8. PMID 32756443 DOI: 10.3390/Vaccines8030434 |
0.431 |
|
| 2019 |
Zacharias ZR, Legge KL. Chronic Ethanol Consumption Reduces Existing CD8 T Cell Memory and Is Associated with Lesions in Protection against Secondary Influenza A Virus Infections. Journal of Immunology (Baltimore, Md. : 1950). PMID 31712384 DOI: 10.4049/Jimmunol.1900770 |
0.621 |
|
| 2019 |
Hornick EE, Zacharias ZR, Legge KL. Kinetics and Phenotype of the CD4 T Cell Response to Influenza Virus Infections. Frontiers in Immunology. 10: 2351. PMID 31632414 DOI: 10.3389/Fimmu.2019.02351 |
0.643 |
|
| 2019 |
Hornick EE, Dagvadorj J, Zacharias ZR, Miller AM, Langlois RA, Chen P, Legge KL, Bishop GA, Sutterwala FS, Cassel SL. Dendritic cell NLRC4 regulates influenza A virus-specific CD4 T cell responses through FasL expression. The Journal of Clinical Investigation. 130. PMID 31038471 DOI: 10.1172/Jci124937 |
0.82 |
|
| 2018 |
Zacharias ZR, Ross KA, Hornick EE, Goodman JT, Narasimhan B, Waldschmidt TJ, Legge KL. Polyanhydride Nanovaccine Induces Robust Pulmonary B and T Cell Immunity and Confers Protection Against Homologous and Heterologous Influenza A Virus Infections. Frontiers in Immunology. 9: 1953. PMID 30233573 DOI: 10.3389/Fimmu.2018.01953 |
0.574 |
|
| 2018 |
Carlin LE, Hemann EA, Zacharias ZR, Heusel JW, Legge KL. Natural Killer Cell Recruitment to the Lung During Influenza A Virus Infection Is Dependent on CXCR3, CCR5, and Virus Exposure Dose. Frontiers in Immunology. 9: 781. PMID 29719539 DOI: 10.3389/Fimmu.2018.00781 |
0.764 |
|
| 2017 |
Hornick EE, Banoth B, Miller AM, Zacharias ZR, Jain N, Wilson ME, Gibson-Corley KN, Legge KL, Bishop GA, Sutterwala FS, Cassel SL. Nlrp12 Mediates Adverse Neutrophil Recruitment during Influenza Virus Infection. Journal of Immunology (Baltimore, Md. : 1950). PMID 29282312 DOI: 10.4049/Jimmunol.1700999 |
0.551 |
|
| 2017 |
Van Braeckel-Budimir N, Martin MD, Hartwig SM, Legge KL, Badovinac VP, Harty JT. Antigen Exposure History Defines CD8 T Cell Dynamics and Protection during Localized Pulmonary Infections. Frontiers in Immunology. 8: 40. PMID 28191007 DOI: 10.3389/Fimmu.2017.00040 |
0.622 |
|
| 2016 |
Strother RK, Danahy DB, Kotov DI, Kucaba TA, Zacharias ZR, Griffith TS, Legge KL, Badovinac VP. Polymicrobial Sepsis Diminishes Dendritic Cell Numbers and Function Directly Contributing to Impaired Primary CD8 T Cell Responses In Vivo. Journal of Immunology (Baltimore, Md. : 1950). PMID 27798171 DOI: 10.4049/Jimmunol.1601463 |
0.57 |
|
| 2016 |
Ulland TK, Jain N, Hornick EE, Elliott EI, Clay GM, Sadler JJ, Mills KA, Janowski AM, Volk AP, Wang K, Legge KL, Gakhar L, Bourdi M, Ferguson PJ, Wilson ME, et al. Nlrp12 mutation causes C57BL/6J strain-specific defect in neutrophil recruitment. Nature Communications. 7: 13180. PMID 27779193 DOI: 10.1038/Ncomms13180 |
0.308 |
|
| 2015 |
Hemann EA, Sjaastad LE, Langlois RA, Legge KL. Plasmacytoid Dendritic Cells Require Direct Infection To Sustain the Pulmonary Influenza A Virus-Specific CD8 T Cell Response. Journal of Virology. 90: 2830-7. PMID 26719269 DOI: 10.1128/Jvi.02546-15 |
0.848 |
|
| 2014 |
Khan SH, Hemann EA, Legge KL, Norian LA, Badovinac VP. Diet-induced obesity does not impact the generation and maintenance of primary memory CD8 T cells. Journal of Immunology (Baltimore, Md. : 1950). 193: 5873-82. PMID 25378592 DOI: 10.4049/Jimmunol.1401685 |
0.757 |
|
| 2014 |
Hemann EA, McGill JL, Legge KL. Chronic ethanol exposure selectively inhibits the influenza-specific CD8 T cell response during influenza a virus infection. Alcoholism, Clinical and Experimental Research. 38: 2403-13. PMID 25160044 DOI: 10.1111/Acer.12522 |
0.845 |
|
| 2014 |
Boyden AW, Frickman AM, Legge KL, Waldschmidt TJ. Primary and long-term B-cell responses in the upper airway and lung after influenza A virus infection. Immunologic Research. 59: 73-80. PMID 24838149 DOI: 10.1007/S12026-014-8541-0 |
0.561 |
|
| 2014 |
Hemann EA, Legge KL. Peripheral regulation of T cells by dendritic cells during infection. Immunologic Research. 59: 66-72. PMID 24838143 DOI: 10.1007/S12026-014-8530-3 |
0.787 |
|
| 2014 |
Boonnak K, Vogel L, Feldmann F, Feldmann H, Legge KL, Subbarao K. Lymphopenia associated with highly virulent H5N1 virus infection due to plasmacytoid dendritic cell-mediated apoptosis of T cells. Journal of Immunology (Baltimore, Md. : 1950). 192: 5906-12. PMID 24829418 DOI: 10.4049/Jimmunol.1302992 |
0.615 |
|
| 2013 |
Hemann EA, Kang SM, Legge KL. Protective CD8 T cell-mediated immunity against influenza A virus infection following influenza virus-like particle vaccination. Journal of Immunology (Baltimore, Md. : 1950). 191: 2486-94. PMID 23885108 DOI: 10.4049/Jimmunol.1300954 |
0.793 |
|
| 2013 |
Hemann E, McGill J, Waldschmidt T, Legge K. Chronic ethanol exposure selectively inhibits the influenza-specific CD8 T cell response during influenza A virus infection Alcohol. 47: 571. DOI: 10.1016/J.Alcohol.2013.09.017 |
0.829 |
|
| 2012 |
Boyden AW, Legge KL, Waldschmidt TJ. Pulmonary infection with influenza A virus induces site-specific germinal center and T follicular helper cell responses. Plos One. 7: e40733. PMID 22792401 DOI: 10.1371/Journal.Pone.0040733 |
0.598 |
|
| 2012 |
Hassan IH, Zhang MS, Powers LS, Shao JQ, Baltrusaitis J, Rutkowski DT, Legge K, Monick MM. Influenza A viral replication is blocked by inhibition of the inositol-requiring enzyme 1 (IRE1) stress pathway. The Journal of Biological Chemistry. 287: 4679-89. PMID 22194594 DOI: 10.1074/Jbc.M111.284695 |
0.447 |
|
| 2012 |
Kulhankova K, Fan K, Tygrett L, Young B, Coleman R, Meyerholz D, Schlueter A, Waldschmidt T, Cook R, Legge K. Fetal/neonatal exposure to ethanol alters pulmonary immunity and increases the severity of respiratory infections Alcohol. 46: 176. DOI: 10.1016/J.Alcohol.2011.09.012 |
0.405 |
|
| 2011 |
Zhao J, Zhao J, Legge K, Perlman S. Age-related increases in PGD(2) expression impair respiratory DC migration, resulting in diminished T cell responses upon respiratory virus infection in mice. The Journal of Clinical Investigation. 121: 4921-30. PMID 22105170 DOI: 10.1172/Jci59777 |
0.595 |
|
| 2011 |
Brincks EL, Gurung P, Langlois RA, Hemann EA, Legge KL, Griffith TS. The magnitude of the T cell response to a clinically significant dose of influenza virus is regulated by TRAIL. Journal of Immunology (Baltimore, Md. : 1950). 187: 4581-8. PMID 21940678 DOI: 10.4049/Jimmunol.1002241 |
0.845 |
|
| 2011 |
Alexander CM, Tygrett LT, Boyden AW, Wolniak KL, Legge KL, Waldschmidt TJ. T regulatory cells participate in the control of germinal centre reactions. Immunology. 133: 452-68. PMID 21635248 DOI: 10.1111/J.1365-2567.2011.03456.X |
0.452 |
|
| 2011 |
Case AJ, McGill JL, Tygrett LT, Shirasawa T, Spitz DR, Waldschmidt TJ, Legge KL, Domann FE. Elevated mitochondrial superoxide disrupts normal T cell development, impairing adaptive immune responses to an influenza challenge. Free Radical Biology & Medicine. 50: 448-58. PMID 21130157 DOI: 10.1016/J.Freeradbiomed.2010.11.025 |
0.712 |
|
| 2011 |
Fan J, Edsen-Moore MR, Turner LE, Cook RT, Legge KL, Waldschmidt TJ, Schlueter AJ. Mechanisms by which chronic ethanol feeding limits the ability of dendritic cells to stimulate T-cell proliferation. Alcoholism, Clinical and Experimental Research. 35: 47-59. PMID 21039629 DOI: 10.1111/J.1530-0277.2010.01321.X |
0.534 |
|
| 2010 |
VanoOsten Anderson R, McGill J, Legge KL. Quantification of the frequency and multiplicity of infection of respiratory- and lymph node-resident dendritic cells during influenza virus infection. Plos One. 5: e12902. PMID 20886117 DOI: 10.1371/Journal.Pone.0012902 |
0.787 |
|
| 2010 |
Pham NL, Pewe LL, Fleenor CJ, Langlois RA, Legge KL, Badovinac VP, Harty JT. Exploiting cross-priming to generate protective CD8 T-cell immunity rapidly. Proceedings of the National Academy of Sciences of the United States of America. 107: 12198-203. PMID 20616089 DOI: 10.1073/Pnas.1004661107 |
0.775 |
|
| 2010 |
Langlois RA, Meyerholz DK, Coleman RA, Cook RT, Waldschmidt TJ, Legge KL. Oseltamivir treatment prevents the increased influenza virus disease severity and lethality occurring in chronic ethanol consuming mice. Alcoholism, Clinical and Experimental Research. 34: 1425-31. PMID 20497135 DOI: 10.1111/J.1530-0277.2010.01226.X |
0.738 |
|
| 2010 |
Langlois RA, Legge KL. Plasmacytoid dendritic cells enhance mortality during lethal influenza infections by eliminating virus-specific CD8 T cells. Journal of Immunology (Baltimore, Md. : 1950). 184: 4440-6. PMID 20220091 DOI: 10.4049/Jimmunol.0902984 |
0.808 |
|
| 2010 |
McGill J, Van Rooijen N, Legge KL. IL-15 trans-presentation by pulmonary dendritic cells promotes effector CD8 T cell survival during influenza virus infection. The Journal of Experimental Medicine. 207: 521-34. PMID 20212069 DOI: 10.1084/Jem.20091711 |
0.781 |
|
| 2009 |
McGill J, Legge KL. Cutting edge: contribution of lung-resident T cell proliferation to the overall magnitude of the antigen-specific CD8 T cell response in the lungs following murine influenza virus infection. Journal of Immunology (Baltimore, Md. : 1950). 183: 4177-81. PMID 19767567 DOI: 10.4049/Jimmunol.0901109 |
0.802 |
|
| 2009 |
McGill J, Heusel JW, Legge KL. Innate immune control and regulation of influenza virus infections. Journal of Leukocyte Biology. 86: 803-12. PMID 19643736 DOI: 10.1189/Jlb.0509368 |
0.74 |
|
| 2009 |
McGill J, Meyerholz DK, Edsen-Moore M, Young B, Coleman RA, Schlueter AJ, Waldschmidt TJ, Cook RT, Legge KL. Fetal exposure to ethanol has long-term effects on the severity of influenza virus infections. Journal of Immunology (Baltimore, Md. : 1950). 182: 7803-8. PMID 19494304 DOI: 10.4049/Jimmunol.0803881 |
0.753 |
|
| 2009 |
Gurung P, Young BM, Coleman RA, Wiechert S, Turner LE, Ray NB, Waldschmidt TJ, Legge KL, Cook RT. Chronic ethanol induces inhibition of antigen-specific CD8+ but not CD4+ immunodominant T cell responses following Listeria monocytogenes inoculation. Journal of Leukocyte Biology. 85: 34-43. PMID 18820175 DOI: 10.1189/Jlb.0208101 |
0.543 |
|
| 2009 |
Scroggins SM, Waldschmidt TJ, Legge KL, Schlueter AJ. Alleviation of Acute Graft-Verus-Host Disease Following Regulatory Dendritic Cell Treatment in Young and Older Mice. Blood. 114: 3550-3550. DOI: 10.1182/Blood.V114.22.3550.3550 |
0.407 |
|
| 2009 |
Case AJ, Mcgill JL, Sangster SC, Madsen JM, Tygrett LT, Johns AG, Takahashi T, Shirasawa T, Spitz DR, Meyerholz DK, Waldschmidt TJ, Legge KL, Domann FE. Heightened Susceptibility to Influenza Mortality in Immunodeficient Mice Caused by a T-Cell Specific Defect in SOD2. Blood. 114: 1655-1655. DOI: 10.1182/Blood.V114.22.1655.1655 |
0.778 |
|
| 2009 |
McGill J, Meyerholz D, Young B, Coleman RA, Schlueter A, Waldschmidt TJ, Cook RT, Legge KL. Fetal exposure to ethanol has long-term effects on influenza viral immunity and disease severity Alcohol. 43: 669. DOI: 10.1016/J.Alcohol.2009.09.016 |
0.615 |
|
| 2009 |
Gurung P, McGill J, Young BM, Coleman RA, Legge KL, Cook RT. Antigen-specific CD8+T cell response are reduced by chronic ethanol and by TLR agonists: CD8+T cell alterations Alcohol. 43: 668. DOI: 10.1016/J.Alcohol.2009.09.011 |
0.744 |
|
| 2008 |
Castilow EM, Legge KL, Varga SM. Cutting edge: Eosinophils do not contribute to respiratory syncytial virus vaccine-enhanced disease. Journal of Immunology (Baltimore, Md. : 1950). 181: 6692-6. PMID 18981084 DOI: 10.4049/Jimmunol.181.10.6692 |
0.425 |
|
| 2008 |
Brincks EL, Katewa A, Kucaba TA, Griffith TS, Legge KL. CD8 T cells utilize TRAIL to control influenza virus infection. Journal of Immunology (Baltimore, Md. : 1950). 181: 4918-25. PMID 18802095 DOI: 10.4049/Jimmunol.181.7.4918 |
0.662 |
|
| 2008 |
Brincks EL, Kucaba TA, Legge KL, Griffith TS. Influenza-induced expression of functional tumor necrosis factor-related apoptosis-inducing ligand on human peripheral blood mononuclear cells. Human Immunology. 69: 634-46. PMID 18723061 DOI: 10.1016/J.Humimm.2008.07.012 |
0.549 |
|
| 2008 |
McGill J, Van Rooijen N, Legge KL. Protective influenza-specific CD8 T cell responses require interactions with dendritic cells in the lungs. The Journal of Experimental Medicine. 205: 1635-46. PMID 18591411 DOI: 10.1084/Jem.20080314 |
0.78 |
|
| 2008 |
Meyerholz DK, Edsen-Moore M, McGill J, Coleman RA, Cook RT, Legge KL. Chronic alcohol consumption increases the severity of murine influenza virus infections. Journal of Immunology (Baltimore, Md. : 1950). 181: 641-8. PMID 18566431 DOI: 10.4049/Jimmunol.181.1.641 |
0.747 |
|
| 2008 |
Legge KL, Schlueter AJ. Dendritic cells in chronic in vivo ethanol exposure models. Methods in Molecular Biology (Clifton, N.J.). 447: 213-33. PMID 18369922 DOI: 10.1007/978-1-59745-242-7_16 |
0.484 |
|
| 2008 |
Meyerholz DK, Edsen-Moore M, McGill J, Coleman RA, Cook RT, Legge KL. Response to Comment on “Chronic Alcohol Consumption Increases the Severity of Murine Influenza Virus Infections” The Journal of Immunology. 181: 5813.2-5814. DOI: 10.4049/Jimmunol.181.9.5813-A |
0.674 |
|
| 2007 |
Langlois RA, Legge KL. Respiratory dendritic cells: mediators of tolerance and immunity. Immunologic Research. 39: 128-45. PMID 17917061 DOI: 10.1007/S12026-007-0077-0 |
0.698 |
|
| 2007 |
Yoon H, Legge KL, Sung SS, Braciale TJ. Sequential activation of CD8+ T cells in the draining lymph nodes in response to pulmonary virus infection. Journal of Immunology (Baltimore, Md. : 1950). 179: 391-9. PMID 17579060 DOI: 10.4049/Jimmunol.179.1.391 |
0.649 |
|
| 2007 |
Meyerholz DK, Edsen M, Coleman RA, Cook RT, Legge KL. Chronic ethanol ingestion in mice enhances influenza A H1N1 pulmonary lesions The Faseb Journal. 21. DOI: 10.1096/Fasebj.21.5.A9-A |
0.372 |
|
| 2006 |
Jabbari A, Legge KL, Harty JT. T cell conditioning explains early disappearance of the memory CD8 T cell response to infection. Journal of Immunology (Baltimore, Md. : 1950). 177: 3012-8. PMID 16920937 DOI: 10.4049/Jimmunol.177.5.3012 |
0.573 |
|
| 2006 |
Edsen M, Katewa A, Coleman RA, Cook RT, Legge KL. Chronic ethanol consumption increases the severity of Influenza A infections Alcohol. 39: 113. DOI: 10.1016/J.Alcohol.2006.09.013 |
0.433 |
|
| 2005 |
Legge KL, Braciale TJ. Lymph node dendritic cells control CD8+ T cell responses through regulated FasL expression. Immunity. 23: 649-59. PMID 16356862 DOI: 10.1016/J.Immuni.2005.11.006 |
0.643 |
|
| 2004 |
Legge KL, Braciale TJ. Respiratory dendritic cells: maturation and migration following pulmonary influenza virus infection International Congress Series. 1263: 149-152. DOI: 10.1016/j.ics.2004.02.027 |
0.446 |
|
| 2003 |
Legge KL, Braciale TJ. Accelerated migration of respiratory dendritic cells to the regional lymph nodes is limited to the early phase of pulmonary infection. Immunity. 18: 265-77. PMID 12594953 DOI: 10.1016/S1074-7613(03)00023-2 |
0.541 |
|
| 2002 |
Legge KL, Gregg RK, Maldonado-Lopez R, Li L, Caprio JC, Moser M, Zaghouani H. On the role of dendritic cells in peripheral T cell tolerance and modulation of autoimmunity. The Journal of Experimental Medicine. 196: 217-27. PMID 12119346 DOI: 10.1084/Jem.20011061 |
0.51 |
|
| 2001 |
Legge KL, Bell JJ, Li L, Gregg R, Caprio JC, Zaghouani H. Multi-modal antigen specific therapy for autoimmunity. International Reviews of Immunology. 20: 593-611. PMID 11890614 DOI: 10.3109/08830180109045580 |
0.374 |
|
| 2001 |
Pack CD, Cestra AE, Min B, Legge KL, Li L, Caprio-Young JC, Bell JJ, Gregg RK, Zaghouani H. Neonatal exposure to antigen primes the immune system to develop responses in various lymphoid organs and promotes bystander regulation of diverse T cell specificities. Journal of Immunology (Baltimore, Md. : 1950). 167: 4187-95. PMID 11591739 DOI: 10.4049/Jimmunol.167.8.4187 |
0.46 |
|
| 2001 |
Li L, Legge KL, Min B, Bell JJ, Gregg R, Caprio J, Zaghouani H. Neonatal immunity develops in a transgenic TCR transfer model and reveals a requirement for elevated cell input to achieve organ-specific responses. Journal of Immunology (Baltimore, Md. : 1950). 167: 2585-94. PMID 11509599 DOI: 10.4049/Jimmunol.167.5.2585 |
0.494 |
|
| 2001 |
Min B, Legge KL, Bell JJ, Gregg RK, Li L, Caprio JC, Zaghouani H. Neonatal exposure to antigen induces a defective CD40 ligand expression that undermines both IL-12 production by APC and IL-2 receptor up-regulation on splenic T cells and perpetuates IFN-gamma-dependent T cell anergy. Journal of Immunology (Baltimore, Md. : 1950). 166: 5594-603. PMID 11313399 DOI: 10.4049/Jimmunol.166.9.5594 |
0.477 |
|
| 2000 |
Legge KL, Min B, Bell JJ, Caprio JC, Li L, Gregg RK, Zaghouani H. Coupling of peripheral tolerance to endogenous interleukin 10 promotes effective modulation of myelin-activated T cells and ameliorates experimental allergic encephalomyelitis. The Journal of Experimental Medicine. 191: 2039-52. PMID 10859329 DOI: 10.1084/Jem.191.12.2039 |
0.484 |
|
| 2000 |
Min B, Legge KL, Li L, Caprio JC, Pack CD, Gregg R, McGavin D, Slauson D, Zaghouani H. Neonatal tolerant immunity for vaccination against autoimmunity. International Reviews of Immunology. 19: 247-64. PMID 10763711 DOI: 10.3109/08830180009088507 |
0.427 |
|
| 2000 |
Min B, Legge KL, Caprio JC, Li L, Gregg R, Zaghouani H. Differential control of neonatal tolerance by antigen dose versus extended exposure and adjuvant. Cellular Immunology. 200: 45-55. PMID 10716882 DOI: 10.1006/Cimm.2000.1618 |
0.364 |
|
| 2000 |
Anderson AC, Nicholson LB, Legge KL, Turchin V, Zaghouani H, Kuchroo VK. High frequency of autoreactive myelin proteolipid protein-specific T cells in the periphery of naive mice: mechanisms of selection of the self-reactive repertoire. The Journal of Experimental Medicine. 191: 761-70. PMID 10704458 DOI: 10.1084/Jem.191.5.761 |
0.452 |
|
| 1998 |
Min B, Legge KL, Pack C, Zaghouani H. Neonatal exposure to a self-peptide-immunoglobulin chimera circumvents the use of adjuvant and confers resistance to autoimmune disease by a novel mechanism involving interleukin 4 lymph node deviation and interferon γ- mediated splenic anergy Journal of Experimental Medicine. 188: 2007-2017. PMID 9841915 DOI: 10.1084/Jem.188.11.2007 |
0.434 |
|
| 1997 |
Legge KL, Min B, Potter NT, Zaghouani H. Presentation of a T cell receptor antagonist peptide by immunoglobulins ablates activation of T cells by a synthetic peptide or proteins requiring endocytic processing. The Journal of Experimental Medicine. 185: 1043-53. PMID 9091578 DOI: 10.1084/Jem.185.6.1043 |
0.4 |
|
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