Jeff Kuret - Publications

Affiliations: 
Ohio State University, Columbus, Columbus, OH 
Area:
Neuroscience Biology, Medical Biophysics, Biochemistry

82 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Ayoub CA, Wagner CS, Kuret J. Identification of gene networks mediating regional resistance to tauopathy in late-onset Alzheimer's disease. Plos Genetics. 19: e1010681. PMID 36972319 DOI: 10.1371/journal.pgen.1010681  0.307
2023 Jimenez-Harrison D, Huseby CJ, Hoffman CN, Sher S, Snyder D, Seal B, Yuan C, Fu H, Wysocki V, Giorgini F, Kuret J. DJ-1 Molecular Chaperone Activity Depresses Tau Aggregation Propensity through Interaction with Monomers. Biochemistry. 62: 976-988. PMID 36813261 DOI: 10.1021/acs.biochem.2c00581  0.52
2022 Chen S, Acosta D, Li L, Liang J, Chang Y, Wang C, Fitzgerald J, Morrison C, Goulbourne CN, Nakano Y, Villegas NCH, Venkataraman L, Brown C, Serrano GE, Bell E, ... ... Kuret J, et al. Wolframin is a novel regulator of tau pathology and neurodegeneration. Acta Neuropathologica. PMID 35389045 DOI: 10.1007/s00401-022-02417-4  0.401
2021 Yang J, Agnihotri MV, Huseby CJ, Kuret J, Singer SJ. A theoretical study of polymorphism in VQIVYK fibrils. Biophysical Journal. PMID 33571490 DOI: 10.1016/j.bpj.2021.01.032  0.437
2020 Liu M, Sui D, Dexheimer T, Hovde S, Deng X, Wang KW, Lin HL, Chien HT, Kweon HK, Kuo NS, Ayoub CA, Jimenez-Harrison D, Andrews PC, Kwok R, Bochar DA, ... Kuret J, et al. Hyperphosphorylation Renders Tau Prone to Aggregate and to Cause Cell Death. Molecular Neurobiology. PMID 32780352 DOI: 10.1007/S12035-020-02034-W  0.606
2019 Huseby CJ, Hoffman CN, Cooper GL, Cocuron JC, Alonso AP, Thomas SN, Yang AJ, Kuret J. Quantification of Tau Protein Lysine Methylation in Aging and Alzheimer's Disease. Journal of Alzheimer's Disease : Jad. PMID 31450505 DOI: 10.3233/Jad-190604  0.492
2019 Huseby CJ, Bundschuh R, Kuret J. The role of annealing and fragmentation in human tau aggregation dynamics. The Journal of Biological Chemistry. PMID 30745358 DOI: 10.1074/Jbc.Ra118.006943  0.599
2017 Yue T, Jia X, Petrosino J, Sun L, Fan Z, Fine J, Davis R, Galster S, Kuret J, Scharre DW, Zhang M. Computational integration of nanoscale physical biomarkers and cognitive assessments for Alzheimer's disease diagnosis and prognosis. Science Advances. 3: e1700669. PMID 28782028 DOI: 10.1126/Sciadv.1700669  0.34
2017 Nanavaty N, Lin L, Hinckley SH, Kuret J. Detection and Quantification Methods for Fibrillar Products of In Vitro Tau Aggregation Assays. Methods in Molecular Biology (Clifton, N.J.). 1523: 101-111. PMID 27975246 DOI: 10.1007/978-1-4939-6598-4_6  0.568
2017 Huseby C, Wagner C, Lin L, Kuret J. Toward a More Robust Gene Expression Signature for Alzheimer's Disease Neurodegeneration Biophysical Journal. 112. DOI: 10.1016/J.Bpj.2016.11.1583  0.349
2016 Huseby CJ, Kuret J. Analyzing Tau Aggregation with Electron Microscopy. Methods in Molecular Biology (Clifton, N.J.). 1345: 101-12. PMID 26453208 DOI: 10.1007/978-1-4939-2978-8_7  0.584
2015 Huseby CJ, Bundschuh R, Kuret J. Tau Filament Length Distribution Reflects End-To-End Annealing Biophysical Journal. 108. DOI: 10.1016/J.Bpj.2014.11.372  0.595
2014 Han DH, Na HK, Choi WH, Lee JH, Kim YK, Won C, Lee SH, Kim KP, Kuret J, Min DH, Lee MJ. Direct cellular delivery of human proteasomes to delay tau aggregation. Nature Communications. 5: 5633. PMID 25476420 DOI: 10.1038/Ncomms6633  0.411
2014 Cisek K, Cooper GL, Huseby CJ, Kuret J. Structure and mechanism of action of tau aggregation inhibitors. Current Alzheimer Research. 11: 918-27. PMID 25387336 DOI: 10.2174/1567205011666141107150331  0.799
2014 Funk KE, Thomas SN, Schafer KN, Cooper GL, Liao Z, Clark DJ, Yang AJ, Kuret J. Lysine methylation is an endogenous post-translational modification of tau protein in human brain and a modulator of aggregation propensity. The Biochemical Journal. 462: 77-88. PMID 24869773 DOI: 10.1042/Bj20140372  0.811
2013 Schafer KN, Cisek K, Huseby CJ, Chang E, Kuret J. Structural determinants of Tau aggregation inhibitor potency. The Journal of Biological Chemistry. 288: 32599-611. PMID 24072703 DOI: 10.1074/Jbc.M113.503474  0.812
2012 Cisek K, Jensen JR, Honson NS, Schafer KN, Cooper GL, Kuret J. Ligand electronic properties modulate tau filament binding site density. Biophysical Chemistry. 170: 25-33. PMID 23072817 DOI: 10.1016/J.Bpc.2012.09.001  0.757
2012 Funk KE, Kuret J. Lysosomal fusion dysfunction as a unifying hypothesis for Alzheimer's disease pathology. International Journal of Alzheimer's Disease. 2012: 752894. PMID 22970406 DOI: 10.1155/2012/752894  0.76
2012 Zhong Q, Congdon EE, Nagaraja HN, Kuret J. Tau isoform composition influences rate and extent of filament formation. The Journal of Biological Chemistry. 287: 20711-9. PMID 22539343 DOI: 10.1074/Jbc.M112.364067  0.571
2012 Cisek K, Kuret J. QSAR studies for prediction of cross-β sheet aggregate binding affinity and selectivity. Bioorganic & Medicinal Chemistry. 20: 1434-41. PMID 22285571 DOI: 10.1016/J.Bmc.2011.12.062  0.759
2012 Schafer KN, Kim S, Matzavinos A, Kuret J. Selectivity requirements for diagnostic imaging of neurofibrillary lesions in Alzheimer's disease: a simulation study. Neuroimage. 60: 1724-33. PMID 22273569 DOI: 10.1016/J.Neuroimage.2012.01.066  0.502
2012 Thomas SN, Funk KE, Wan Y, Liao Z, Davies P, Kuret J, Yang AJ. Dual modification of Alzheimer's disease PHF-tau protein by lysine methylation and ubiquitylation: a mass spectrometry approach. Acta Neuropathologica. 123: 105-17. PMID 22033876 DOI: 10.1007/S00401-011-0893-0  0.794
2011 Jensen JR, Cisek K, Funk KE, Naphade S, Schafer KN, Kuret J. Research towards tau imaging. Journal of Alzheimer's Disease : Jad. 26: 147-57. PMID 21971459 DOI: 10.3233/Jad-2011-0003  0.819
2011 Jensen JR, Cisek K, Honson NS, Kuret J. Ligand polarizability contributes to tau fibril binding affinity. Bioorganic & Medicinal Chemistry. 19: 5147-54. PMID 21803586 DOI: 10.1016/J.Bmc.2011.07.016  0.79
2011 Schafer KN, Murale DP, Kim K, Cisek K, Kuret J, Churchill DG. Structure-activity relationship of cyclic thiacarbocyanine tau aggregation inhibitors. Bioorganic & Medicinal Chemistry Letters. 21: 3273-6. PMID 21549596 DOI: 10.1016/J.Bmcl.2011.04.039  0.785
2011 Chang E, Kim S, Schafer KN, Kuret J. Pseudophosphorylation of tau protein directly modulates its aggregation kinetics. Biochimica Et Biophysica Acta. 1814: 388-95. PMID 20974297 DOI: 10.1016/J.Bbapap.2010.10.005  0.629
2011 Funk KE, Mrak RE, Kuret J. Granulovacuolar degeneration (GVD) bodies of Alzheimer's disease (AD) resemble late-stage autophagic organelles. Neuropathology and Applied Neurobiology. 37: 295-306. PMID 20946470 DOI: 10.1111/J.1365-2990.2010.01135.X  0.749
2010 Duff K, Kuret J, Congdon EE. Disaggregation of tau as a therapeutic approach to tauopathies. Current Alzheimer Research. 7: 235-40. PMID 20088807 DOI: 10.2174/156720510791050885  0.521
2010 Kim S, Jensen JR, Cisek K, Funk KE, Naphade S, Schafer K, Kuret J. Imaging as a strategy for premortem diagnosis and staging of tauopathies. Current Alzheimer Research. 7: 230-4. PMID 20088805 DOI: 10.2174/156720510791050894  0.789
2009 Chang E, Honson NS, Bandyopadhyay B, Funk KE, Jensen JR, Kim S, Naphade S, Kuret J. Modulation and detection of tau aggregation with small-molecule ligands. Current Alzheimer Research. 6: 409-14. PMID 19874263 DOI: 10.2174/156720509789207976  0.832
2009 Congdon EE, Figueroa YH, Wang L, Toneva G, Chang E, Kuret J, Conrad C, Duff KE. Inhibition of tau polymerization with a cyanine dye in two distinct model systems. The Journal of Biological Chemistry. 284: 20830-9. PMID 19478088 DOI: 10.1074/Jbc.M109.016089  0.577
2009 Chang E, Congdon EE, Honson NS, Duff KE, Kuret J. Structure-activity relationship of cyanine tau aggregation inhibitors. Journal of Medicinal Chemistry. 52: 3539-47. PMID 19432420 DOI: 10.1021/Jm900116D  0.545
2009 Honson NS, Jensen JR, Abraha A, Hall GF, Kuret J. Small-molecule mediated neuroprotection in an in situ model of tauopathy. Neurotoxicity Research. 15: 274-83. PMID 19384600 DOI: 10.1007/S12640-009-9028-Y  0.563
2008 Chang E, Kim S, Yin H, Nagaraja HN, Kuret J. Pathogenic missense MAPT mutations differentially modulate tau aggregation propensity at nucleation and extension steps. Journal of Neurochemistry. 107: 1113-23. PMID 18803694 DOI: 10.1111/J.1471-4159.2008.05692.X  0.699
2008 Honson NS, Kuret J. Tau aggregation and toxicity in tauopathic neurodegenerative diseases. Journal of Alzheimer's Disease : Jad. 14: 417-22. PMID 18688092 DOI: 10.3233/Jad-2008-14409  0.586
2008 Trojanowski JQ, Duff K, Fillit H, Koroshetz W, Kuret J, Murphy D, Refolo L. New directions for frontotemporal dementia drug discovery. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 4: 89-93. PMID 18631953 DOI: 10.1016/J.Jalz.2007.06.001  0.337
2008 Sarkar M, Kuret J, Lee G. Two motifs within the tau microtubule-binding domain mediate its association with the hsc70 molecular chaperone. Journal of Neuroscience Research. 86: 2763-73. PMID 18500754 DOI: 10.1002/Jnr.21721  0.546
2008 Congdon EE, Kim S, Bonchak J, Songrug T, Matzavinos A, Kuret J. Nucleation-dependent tau filament formation: the importance of dimerization and an estimation of elementary rate constants. The Journal of Biological Chemistry. 283: 13806-16. PMID 18359772 DOI: 10.1074/Jbc.M800247200  0.596
2008 Kannanayakal TJ, Mendell JR, Kuret J. Casein kinase 1 alpha associates with the tau-bearing lesions of inclusion body myositis. Neuroscience Letters. 431: 141-5. PMID 18191026 DOI: 10.1016/J.Neulet.2007.11.066  0.513
2008 Chang E, Kuret J. Detection and quantification of tau aggregation using a membrane filter assay. Analytical Biochemistry. 373: 330-6. PMID 17949677 DOI: 10.1016/J.Ab.2007.09.015  0.484
2008 Kuret J, Zhong Q, Congdon EE. O2-05-07: How do Tau isoform expression patterns influence neurofibrillary lesion formation in tauopathies? Alzheimers & Dementia. 4. DOI: 10.1016/J.Jalz.2008.05.346  0.395
2008 Honson NS, Bhandyopadhyay B, Chang E, Naphade SB, Jensen JR, Kuret J. P2-179: Small-molecule probes of tau fibrillization Alzheimers & Dementia. 4. DOI: 10.1016/J.Jalz.2008.05.1253  0.463
2007 Honson NS, Jensen JR, Darby MV, Kuret J. Potent inhibition of tau fibrillization with a multivalent ligand. Biochemical and Biophysical Research Communications. 363: 229-34. PMID 17854770 DOI: 10.1016/J.Bbrc.2007.08.166  0.59
2007 Honson NS, Johnson RL, Huang W, Inglese J, Austin CP, Kuret J. Differentiating Alzheimer disease-associated aggregates with small molecules. Neurobiology of Disease. 28: 251-60. PMID 17761424 DOI: 10.1016/J.Nbd.2007.07.018  0.539
2007 Congdon EE, Necula M, Blackstone RD, Kuret J. Potency of a tau fibrillization inhibitor is influenced by its aggregation state. Archives of Biochemistry and Biophysics. 465: 127-35. PMID 17559794 DOI: 10.1016/J.Abb.2007.05.004  0.792
2007 Bandyopadhyay B, Li G, Yin H, Kuret J. Tau aggregation and toxicity in a cell culture model of tauopathy. The Journal of Biological Chemistry. 282: 16454-64. PMID 17428800 DOI: 10.1074/Jbc.M700192200  0.735
2006 Yin H, Laguna KA, Li G, Kuret J. Dysbindin structural homologue CK1BP is an isoform-selective binding partner of human casein kinase-1. Biochemistry. 45: 5297-308. PMID 16618118 DOI: 10.1021/Bi052354E  0.625
2006 Kannanayakal TJ, Tao H, Vandre DD, Kuret J. Casein kinase-1 isoforms differentially associate with neurofibrillary and granulovacuolar degeneration lesions. Acta Neuropathologica. 111: 413-21. PMID 16557393 DOI: 10.1007/S00401-006-0049-9  0.434
2006 Yin H, Kuret J. C-terminal truncation modulates both nucleation and extension phases of tau fibrillization. Febs Letters. 580: 211-5. PMID 16364303 DOI: 10.1016/J.Febslet.2005.11.077  0.758
2005 Kuret J, Congdon EE, Li G, Yin H, Yu X, Zhong Q. Evaluating triggers and enhancers of tau fibrillization. Microscopy Research and Technique. 67: 141-55. PMID 16103995 DOI: 10.1002/Jemt.20187  0.766
2005 Necula M, Chirita CN, Kuret J. Cyanine dye N744 inhibits tau fibrillization by blocking filament extension: implications for the treatment of tauopathic neurodegenerative diseases. Biochemistry. 44: 10227-37. PMID 16042400 DOI: 10.1021/Bi050387O  0.839
2005 Chirita CN, Congdon EE, Yin H, Kuret J. Triggers of full-length tau aggregation: a role for partially folded intermediates. Biochemistry. 44: 5862-72. PMID 15823045 DOI: 10.1021/Bi0500123  0.844
2005 Necula M, Kuret J. Site-specific pseudophosphorylation modulates the rate of tau filament dissociation. Febs Letters. 579: 1453-7. PMID 15733856 DOI: 10.1016/J.Febslet.2005.01.047  0.794
2005 Kuret J, Chirita CN, Congdon EE, Kannanayakal T, Li G, Necula M, Yin H, Zhong Q. Pathways of tau fibrillization. Biochimica Et Biophysica Acta. 1739: 167-78. PMID 15615636 DOI: 10.1016/J.Bbadis.2004.06.016  0.832
2004 Necula M, Kuret J. A static laser light scattering assay for surfactant-induced tau fibrillization. Analytical Biochemistry. 333: 205-15. PMID 15450794 DOI: 10.1016/J.Ab.2004.05.044  0.766
2004 Necula M, Kuret J. Pseudophosphorylation and glycation of tau protein enhance but do not trigger fibrillization in vitro. The Journal of Biological Chemistry. 279: 49694-703. PMID 15364924 DOI: 10.1074/Jbc.M405527200  0.812
2004 Necula M, Kuret J. Electron microscopy as a quantitative method for investigating tau fibrillization. Analytical Biochemistry. 329: 238-46. PMID 15158482 DOI: 10.1016/J.Ab.2004.02.023  0.79
2004 Chirita C, Necula M, Kuret J. Ligand-dependent inhibition and reversal of tau filament formation. Biochemistry. 43: 2879-87. PMID 15005623 DOI: 10.1021/Bi036094H  0.841
2004 Chirita CN, Kuret J. Evidence for an intermediate in tau filament formation. Biochemistry. 43: 1704-14. PMID 14769048 DOI: 10.1021/Bi036034B  0.852
2004 Li G, Yin H, Kuret J. Casein kinase 1 delta phosphorylates tau and disrupts its binding to microtubules. The Journal of Biological Chemistry. 279: 15938-45. PMID 14761950 DOI: 10.1074/Jbc.M314116200  0.728
2004 Necula M, Chirita CN, Kuret J. P4-423 Pharmacological modulation of tau fibrillization in vitro Neurobiology of Aging. 25: S594. DOI: 10.1016/S0197-4580(04)81979-1  0.808
2004 Kuret J, Chirita C, Congdon E, Necula M, Yin H, Li G. P3-271 Mechanism of tau fibrillation in vitro Neurobiology of Aging. 25: S431-S432. DOI: 10.1016/S0197-4580(04)81421-0  0.805
2004 Kannanayakal T, Yin H, Zhong Q, Li G, Kuret J. P3-265 Casein kinase 1 phosphorylates tau and colocalizes with lesions in Alzheimer's disease and inclusion body myositis Neurobiology of Aging. 25: S430. DOI: 10.1016/S0197-4580(04)81415-5  0.682
2004 Chirita CN, Congdon E, Kuret J. P3-233 Kinetic pathway of tau filament formation Neurobiology of Aging. 25: S421. DOI: 10.1016/S0197-4580(04)81383-6  0.82
2003 Necula M, Chirita CN, Kuret J. Rapid anionic micelle-mediated alpha-synuclein fibrillization in vitro. The Journal of Biological Chemistry. 278: 46674-80. PMID 14506232 DOI: 10.1074/Jbc.M308231200  0.778
2003 Chirita CN, Necula M, Kuret J. Anionic micelles and vesicles induce tau fibrillization in vitro. The Journal of Biological Chemistry. 278: 25644-50. PMID 12730214 DOI: 10.1074/Jbc.M301663200  0.821
2002 Yu JZ, Kuret J, Rasenick MM. Transient expression of fluorescent tau proteins promotes process formation in PC12 cells: Contributions of the tau C-terminus to this process Journal of Neuroscience Research. 67: 625-633. PMID 11891775 DOI: 10.1002/Jnr.10152  0.547
2002 Kuret J, Johnson GS, Cha D, Christenson ER, DeMaggio AJ, Hoekstra MF. Casein kinase 1 is tightly associated with paired-helical filaments isolated from Alzheimer's disease brain. Journal of Neurochemistry. 69: 2506-2515. PMID 9375684 DOI: 10.1046/J.1471-4159.1997.69062506.X  0.462
2001 Ghoshal N, García-Sierra F, Fu Y, Beckett LA, Mufson EJ, Kuret J, Berry RW, Binder LI. Tau-66: evidence for a novel tau conformation in Alzheimer's disease. Journal of Neurochemistry. 77: 1372-85. PMID 11389188 DOI: 10.1046/J.1471-4159.2001.00346.X  0.589
2000 Gamblin TC, King ME, Kuret J, Berry RW, Binder LI. Oxidative regulation of fatty acid-induced tau polymerization Biochemistry. 39: 14203-14210. PMID 11087369 DOI: 10.1021/Bi001876L  0.423
2000 Schwab C, DeMaggio AJ, Ghoshal N, Binder LI, Kuret J, McGeer PL. Casein kinase 1 delta is associated with pathological accumulation of tau in several neurodegenerative diseases. Neurobiology of Aging. 21: 503-10. PMID 10924763 DOI: 10.1016/S0197-4580(00)00110-X  0.467
2000 Gamblin TC, King ME, Dawson H, Vitek MP, Kuret J, Berry RW, Binder LI. In vitro polymerization of tau protein monitored by laser light scattering: Method and application to the study of FTDP-17 mutants Biochemistry. 39: 6136-6144. PMID 10821687 DOI: 10.1021/Bi000201F  0.477
2000 Yasojima K, Kuret J, DeMaggio AJ, McGeer E, McGeer PL. Casein kinase 1 delta mRNA is upregulated in Alzheimer disease brain. Brain Research. 865: 116-20. PMID 10814741 DOI: 10.1016/S0006-8993(00)02200-9  0.496
2000 Mashhoon N, DeMaggio AJ, Tereshko V, Bergmeier SC, Egli M, Hoekstra MF, Kuret J. Crystal structure of a conformation-selective casein kinase-1 inhibitor. The Journal of Biological Chemistry. 275: 20052-60. PMID 10749871 DOI: 10.1074/Jbc.M001713200  0.303
2000 Kuret J, Abraha A, Gamblin TC, Grau L, King ME, Binder LI. The structural basis of tau filament formation Neurobiology of Aging. 21: 132-133. DOI: 10.1016/S0197-4580(00)82395-7  0.506
2000 Kuret J, Binder LI, Hoekstra MF, Demaggio AJ. A new molecular link between granulovacuolar and neurofibrillary lesions of Alzheimer's disease Neurobiology of Aging. 21: 191. DOI: 10.1016/S0197-4580(00)82202-2  0.419
1999 King ME, Ahuja V, Binder LI, Kuret J. Ligand-dependent tau filament formation: Implications for Alzheimer's disease progression Biochemistry. 38: 14851-14859. PMID 10555967 DOI: 10.1021/Bi9911839  0.58
1999 Ghoshal N, Smiley JF, DeMaggio AJ, Hoekstra MF, Cochran EJ, Binder LI, Kuret J. A new molecular link between the fibrillar and granulovacuolar lesions of Alzheimer's disease. The American Journal of Pathology. 155: 1163-72. PMID 10514399 DOI: 10.1016/S0002-9440(10)65219-4  0.51
1999 Vancurova I, Choi JH, Lin H, Kuret J, Vancura A. Regulation of phosphatidylinositol 4-phosphate 5-kinase from Schizosaccharomyces pombe by casein kinase I. The Journal of Biological Chemistry. 274: 1147-55. PMID 9873063 DOI: 10.1074/Jbc.274.2.1147  0.314
1998 Murthy SNP, Wilson JH, Lukas TJ, Kuret J, Lorand L. Cross-linking sites of the human tau protein, probed by reactions with human transglutaminase Journal of Neurochemistry. 71: 2607-2614. PMID 9832162 DOI: 10.1046/J.1471-4159.1998.71062607.X  0.514
1996 Carmel G, Mager EM, Binder LI, Kuret J. The structural basis of monoclonal antibody Alz50's selectivity for Alzheimer's disease pathology Journal of Biological Chemistry. 271: 32789-32795. PMID 8955115 DOI: 10.1074/Jbc.271.51.32789  0.465
1985 Schulman H, Kuret J, Jefferson AB, Nose PS, Spitzer KH. Ca2+/calmodulin-dependent microtubule-associated protein 2 kinase: broad substrate specificity and multifunctional potential in diverse tissues. Biochemistry. 24: 5320-7. PMID 4074698 DOI: 10.1021/Bi00341A008  0.312
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