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Andrean L. Simons, Ph.D. - Publications

Affiliations: 
2005 Iowa State University, Ames, IA, United States 
Area:
Nutrition, Microbiology Biology, Toxicology
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29 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Rajan A, Gibson-Corley KN, Choi AB, Ofori-Amanfo GK, Ten Eyck P, Espinosa-Cotton M, Sperry SM, Simons AL. Impact of Nuclear Interleukin-1 Alpha and EGFR Expression on Recurrence and Survival Outcomes in Oral Squamous Cell Carcinomas. Journal of Oncology. 2019: 5859680. PMID 31320902 DOI: 10.1155/2019/5859680  0.308
2019 Espinosa-Cotton M, Rodman Iii SN, Ross KA, Jensen IJ, Sangodeyi-Miller K, McLaren AJ, Dahl RA, Gibson-Corley KN, Koch AT, Fu YX, Badovinac VP, Laux D, Narasimhan B, Simons AL. Interleukin-1 alpha increases anti-tumor efficacy of cetuximab in head and neck squamous cell carcinoma. Journal For Immunotherapy of Cancer. 7: 79. PMID 30890189 DOI: 10.1186/S40425-019-0550-Z  0.327
2017 Simons A, Stanam A, Koch A, Espinosa-Cotton M, Gibson-Corley K. Abstract 48: Targeting IL-1 signaling to improve tumor response to erlotinib in HNSCC Clinical Cancer Research. 23: 48-48. DOI: 10.1158/1557-3265.Aacrahns17-48  0.326
2017 Simons AL, Stanam A, Gibson-Corley KN. Abstract 4163: Blockade of the interleukin-1 signaling pathway overcomes erlotinib resistance in head and neck cancer cells Cancer Research. 77: 4163-4163. DOI: 10.1158/1538-7445.Am2017-4163  0.337
2017 Espinosa-Cotton M, McLaren AJ, Koch AT, Simons AL. Abstract 3705: Targeting interleukin-1 to increase cetuximab efficacy in head and neck cancer Cancer Research. 77: 3705-3705. DOI: 10.1158/1538-7445.Am2017-3705  0.312
2017 Espinosa-Cotton M, Dahl RA, Miller K, Simons AL. Interleukin-1 Signaling is Required for HNSCC Tumor Response to Cetuximab Free Radical Biology and Medicine. 112: 87-88. DOI: 10.1016/J.Freeradbiomed.2017.10.127  0.32
2016 Stanam A, Gibson-Corley KN, Love-Homan L, Ihejirika N, Simons AL. Interleukin-1 blockade overcomes erlotinib resistance in head and neck squamous cell carcinoma. Oncotarget. PMID 27738319 DOI: 10.18632/Oncotarget.12590  0.338
2016 Sobhakumari A, Orcutt KP, Love-Homan L, Kowalski CE, Parsons AD, Knudson CM, Simons AL. 2-Deoxy-d-glucose Suppresses the In Vivo Antitumor Efficacy of Erlotinib in Head and Neck Squamous Cell Carcinoma Cells. Oncology Research. 24: 55-64. PMID 27178822 DOI: 10.3727/096504016X14586627440192  0.339
2015 Stanam A, Love-Homan L, Joseph TS, Espinosa-Cotton M, Simons AL. Upregulated interleukin-6 expression contributes to erlotinib resistance in head and neck squamous cell carcinoma. Molecular Oncology. PMID 25888065 DOI: 10.1016/J.Molonc.2015.03.008  0.328
2015 Koch AT, Love-Homan L, Espinosa-Cotton M, Stanam A, Simons AL. MyD88-Dependent Signaling Decreases the Antitumor Efficacy of Epidermal Growth Factor Receptor Inhibition in Head and Neck Cancer Cells. Cancer Research. 75: 1657-67. PMID 25712126 DOI: 10.1158/0008-5472.Can-14-2061  0.354
2015 Simons AL, Koch AT, Love-Homan L, Stanam A. Abstract B29: The role of MYD88-dependent signaling in the anti-tumor efficacy of the EGFR inhibitor erlotinib in head and neck cancer cells Clinical Cancer Research. 21. DOI: 10.1158/1557-3265.Pms14-B29  0.32
2013 Fletcher EV, Love-Homan L, Sobhakumari A, Feddersen CR, Koch AT, Goel A, Simons AL. EGFR inhibition induces proinflammatory cytokines via NOX4 in HNSCC. Molecular Cancer Research : McR. 11: 1574-84. PMID 24048704 DOI: 10.1158/1541-7786.Mcr-13-0187  0.311
2013 Sobhakumari A, Schickling BM, Love-Homan L, Raeburn A, Fletcher EV, Case AJ, Domann FE, Miller FJ, Simons AL. NOX4 mediates cytoprotective autophagy induced by the EGFR inhibitor erlotinib in head and neck cancer cells. Toxicology and Applied Pharmacology. 272: 736-45. PMID 23917044 DOI: 10.1016/J.Taap.2013.07.013  0.32
2013 Du J, Nelson ES, Simons AL, Olney KE, Moser JC, Schrock HE, Wagner BA, Buettner GR, Smith BJ, Teoh ML, Tsao MS, Cullen JJ. Regulation of pancreatic cancer growth by superoxide. Molecular Carcinogenesis. 52: 555-67. PMID 22392697 DOI: 10.1002/Mc.21891  0.308
2012 Sobhakumari A, Love-Homan L, Fletcher EV, Martin SM, Parsons AD, Spitz DR, Knudson CM, Simons AL. Susceptibility of human head and neck cancer cells to combined inhibition of glutathione and thioredoxin metabolism. Plos One. 7: e48175. PMID 23118946 DOI: 10.1371/Journal.Pone.0048175  0.38
2011 Orcutt KP, Parsons AD, Sibenaller ZA, Scarbrough PM, Zhu Y, Sobhakumari A, Wilke WW, Kalen AL, Goswami P, Miller FJ, Spitz DR, Simons AL. Erlotinib-mediated inhibition of EGFR signaling induces metabolic oxidative stress through NOX4. Cancer Research. 71: 3932-40. PMID 21482679 DOI: 10.1158/0008-5472.Can-10-3425  0.303
2011 Fletcher EV, Sobhakumari A, Brown CO, Case AJ, Spitz DR, Domann FE, Goel A, Simons AL. EGFR Inhibition Induces IL6 Expression Via NOX4 in Head and Neck Cancer Cells Free Radical Biology and Medicine. 51: S133-S134. DOI: 10.1016/J.Freeradbiomed.2011.10.278  0.319
2010 Simons AL, Renouf M, Murphy PA, Hendrich S. Greater apparent absorption of flavonoids is associated with lesser human fecal flavonoid disappearance rates. Journal of Agricultural and Food Chemistry. 58: 141-7. PMID 19921837 DOI: 10.1021/Jf902284U  0.657
2010 Simons AL, Orcutt KP, Parsons AD, Sibenaller ZA, Scarbrough PM, Sobhakumari A, Zhu Y, Wilke WW, Kalen AL, Miller FJ, Goswami P, Spitz DR. Inhibition of EGFR Signaling Induces Metabolic Oxidative Stress in Human Head and Neck Cancer Cells Free Radical Biology and Medicine. 49: S102-S103. DOI: 10.1016/J.Freeradbiomed.2010.10.270  0.358
2010 Sobhakumari A, Parsons A, McCormick M, Spitz DR, Simons A. Head and Neck Cancer Cells Exhibit an Adaptive Response to the AKT-inhibitor Perifosine Characterized by Increased Glucose Metabolism and Altered Signaling Through the AKT Pathway Free Radical Biology and Medicine. 49: S71. DOI: 10.1016/J.Freeradbiomed.2010.10.176  0.317
2009 Simons AL, Mattson DM, Dornfeld K, Spitz DR. Glucose deprivation-induced metabolic oxidative stress and cancer therapy. Journal of Cancer Research and Therapeutics. 5: S2-6. PMID 20009288 DOI: 10.4103/0973-1482.55133  0.319
2009 Simons AL, Parsons AD, Foster KA, Orcutt KP, Fath MA, Spitz DR. Inhibition of glutathione and thioredoxin metabolism enhances sensitivity to perifosine in head and neck cancer cells. Journal of Oncology. 2009: 519563. PMID 19746172 DOI: 10.1155/2009/519563  0.372
2009 Fath MA, Diers AR, Aykin-Burns N, Simons AL, Hua L, Spitz DR. Mitochondrial electron transport chain blockers enhance 2-deoxy-D-glucose induced oxidative stress and cell killing in human colon carcinoma cells. Cancer Biology & Therapy. 8: 1228-36. PMID 19411865 DOI: 10.4161/Cbt.8.13.8631  0.361
2009 Orcutt K, Wilke W, Scarbrough P, Kalen A, Spitz D, Simons A. The Role of Oxidative Stress in the Cytotoxic Effects of Erlotinib in Human Head and Neck Cancer Cells International Journal of Radiation Oncology*Biology*Physics. 75: S565. DOI: 10.1016/J.Ijrobp.2009.07.1292  0.312
2008 Ahmad IM, Abdalla MY, Aykin-Burns N, Simons AL, Oberley LW, Domann FE, Spitz DR. 2-Deoxyglucose combined with wild-type p53 overexpression enhances cytotoxicity in human prostate cancer cells via oxidative stress. Free Radical Biology & Medicine. 44: 826-34. PMID 18155176 DOI: 10.1016/J.Freeradbiomed.2007.11.007  0.35
2007 Simons AL, Ahmad IM, Mattson DM, Dornfeld KJ, Spitz DR. 2-Deoxy-D-glucose combined with cisplatin enhances cytotoxicity via metabolic oxidative stress in human head and neck cancer cells. Cancer Research. 67: 3364-70. PMID 17409446 DOI: 10.1158/0008-5472.Can-06-3717  0.356
2005 Simons AL, Renouf M, Hendrich S, Murphy PA. Metabolism of glycitein (7,4'-dihydroxy-6-methoxy-isoflavone) by human gut microflora. Journal of Agricultural and Food Chemistry. 53: 8519-25. PMID 16248547 DOI: 10.1021/Jf051546D  0.659
2005 Lee SO, Simons AL, Murphy PA, Hendrich S. Soyasaponins lowered plasma cholesterol and increased fecal bile acids in female golden Syrian hamsters. Experimental Biology and Medicine (Maywood, N.J.). 230: 472-8. PMID 15985622 DOI: 10.1177/153537020523000705  0.636
2005 Simons AL, Renouf M, Hendrich S, Murphy PA. Human gut microbial degradation of flavonoids: structure-function relationships. Journal of Agricultural and Food Chemistry. 53: 4258-63. PMID 15884869 DOI: 10.1021/Jf0500177  0.648
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