Roland M. Tisch - Publications

Affiliations: 
Microbiology & Immunology University of North Carolina, Chapel Hill, Chapel Hill, NC 
Area:
Immunology

108 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Au KM, Tisch R, Wang AZ. Bioengineering of Beta Cells with Immune Checkpoint Ligand as a Treatment for Early-Onset Type 1 Diabetes Mellitus. Acs Nano. PMID 34843648 DOI: 10.1021/acsnano.1c07538  0.421
2021 Au KM, Tisch R, Wang AZ. Immune Checkpoint Ligand-Bioengineered Schwann Cells as Antigen-Specific Therapy for Experimental Autoimmune Encephalomyelitis. Advanced Materials (Deerfield Beach, Fla.). e2107392. PMID 34775659 DOI: 10.1002/adma.202107392  0.386
2021 Clark M, Kroger CJ, Ke Q, Zhang R, Statum K, Milner JJ, Martin AJ, Wang B, Tisch R. Coreceptor therapy has distinct short- and long-term tolerogenic effects intrinsic to autoreactive effector T cells. Jci Insight. PMID 34314385 DOI: 10.1172/jci.insight.149130  0.473
2021 Au KM, Medik Y, Ke Q, Tisch R, Wang AZ. Immune Checkpoint-Bioengineered Beta Cell Vaccine Reverses Early-Onset Type 1 Diabetes. Advanced Materials (Deerfield Beach, Fla.). e2101253. PMID 33963786 DOI: 10.1002/adma.202101253  0.449
2020 Ke Q, Kroger CJ, Clark M, Tisch RM. Evolving Antibody Therapies for the Treatment of Type 1 Diabetes. Frontiers in Immunology. 11: 624568. PMID 33679717 DOI: 10.3389/fimmu.2020.624568  0.4
2020 Clark M, Kroger CJ, Ke Q, Tisch RM. The Role of T Cell Receptor Signaling in the Development of Type 1 Diabetes. Frontiers in Immunology. 11: 615371. PMID 33603744 DOI: 10.3389/fimmu.2020.615371  0.483
2018 Brehm MA, Kenney LL, Wiles MV, Low BE, Tisch RM, Burzenski L, Mueller C, Greiner DL, Shultz LD. Lack of acute xenogeneic graft- versus-host disease, but retention of T-cell function following engraftment of human peripheral blood mononuclear cells in NSG mice deficient in MHC class I and II expression. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. fj201800636R. PMID 30383447 DOI: 10.1096/Fj.201800636R  0.503
2018 Kroger CJ, Clark M, Ke Q, Tisch RM. Therapies to Suppress β Cell Autoimmunity in Type 1 Diabetes. Frontiers in Immunology. 9: 1891. PMID 30166987 DOI: 10.3389/Fimmu.2018.01891  0.506
2018 Chen N, Kroger CJ, Tisch RM, Bachelder EM, Ainslie KM. Prevention of Type 1 Diabetes with Acetalated Dextran Microparticles Containing Rapamycin and Pancreatic Peptide P31. Advanced Healthcare Materials. e1800341. PMID 30051618 DOI: 10.1002/Adhm.201800341  0.628
2018 Brehm MA, Wiles M, Kenney L, Low B, Tisch RM, Burzenski L, Keck JG, Greiner DL, Shultz LD. Abstract 5665: NOD-scid IL2rgnull (NSG) mice deficient in murine MHC Class I and Class II expression support engraftment of functional human T cells in the absence of acute xenogeneic GVHD following injection of PBMC Cancer Research. 78: 5665-5665. DOI: 10.1158/1538-7445.Am2018-5665  0.469
2017 Clark M, Kroger CJ, Tisch RM. Type 1 Diabetes: A Chronic Anti-Self-Inflammatory Response. Frontiers in Immunology. 8: 1898. PMID 29312356 DOI: 10.3389/Fimmu.2017.01898  0.549
2017 Durost P, Aryee KE, Manzoor F, Tisch R, Mueller C, Jurczyk A, Shultz L, Brehm M. Gene therapy with an AAV vector expressing human IL-2 alters immune system homeostasis in humanized mice. Human Gene Therapy. PMID 28826231 DOI: 10.1089/Hum.2017.072  0.446
2016 Keener AB, Thurlow LT, Kang S, Spidale NA, Clarke SH, Cunnion KM, Tisch R, Richardson AR, Vilen BJ. Staphylococcus aureus Protein A Disrupts Immunity Mediated by Long-Lived Plasma Cells. Journal of Immunology (Baltimore, Md. : 1950). PMID 28031339 DOI: 10.4049/Jimmunol.1600093  0.394
2016 Kroger CJ, Spidale NA, Wang B, Tisch R. Thymic Dendritic Cell Subsets Display Distinct Efficiencies and Mechanisms of Intercellular MHC Transfer. Journal of Immunology (Baltimore, Md. : 1950). PMID 27895179 DOI: 10.4049/Jimmunol.1601516  0.422
2016 Manzoor F, Johnson MC, Li C, Samulski RJ, Wang B, Tisch R. β-cell-specific IL-35 therapy suppresses ongoing autoimmune diabetes in NOD mice. European Journal of Immunology. PMID 27859048 DOI: 10.1002/Eji.201646493  0.591
2016 Martin AJ, Clark M, Gojanovich G, Manzoor F, Miller K, Kline DE, Morillon YM, Wang B, Tisch R. Anti-coreceptor therapy drives selective T cell egress by suppressing inflammation-dependent chemotactic cues. Jci Insight. 1: e87636. PMID 27777971 DOI: 10.1172/Jci.Insight.87636  0.604
2016 Morillon YM, Lessey-Morillon EC, Clark M, Zhang R, Wang B, Burridge K, Tisch R. Antibody Binding to CD4 Induces Rac GTPase Activation and Alters T Cell Migration. Journal of Immunology (Baltimore, Md. : 1950). PMID 27694496 DOI: 10.4049/Jimmunol.1501600  0.579
2016 Kroger CJ, Wang B, Tisch R. Temporal increase in thymocyte negative selection parallels enhanced thymic SIRPα(+) DC function. European Journal of Immunology. PMID 27501268 DOI: 10.1002/Eji.201646354  0.459
2015 Combs TP, Snell-Bergeon JK, Maahs DM, Bergman BC, Lamarche M, Iberkleid L, AbdelBaky O, Tisch R, Scherer PE, Marliss EB. Adiponectin-SOGA Dissociation in Type 1 Diabetes. The Journal of Clinical Endocrinology and Metabolism. 100: E1065-73. PMID 26052615 DOI: 10.1210/Jc.2015-1275  0.387
2015 Morillon YM, Manzoor F, Wang B, Tisch R. Isolation and transplantation of different aged murine thymic grafts Journal of Visualized Experiments. 2015. PMID 25992870 DOI: 10.3791/52709  0.435
2015 Maurice Morillon Y, Martin A, Gojanovich G, Wang B, Tisch R. Reestablishing T Cell Tolerance by Antibody-Based Therapy in Type 1 Diabetes. Archivum Immunologiae Et Therapiae Experimentalis. 63: 239-50. PMID 25790749 DOI: 10.1007/S00005-015-0336-Z  0.543
2014 Mizui M, Koga T, Lieberman LA, Beltran J, Yoshida N, Johnson MC, Tisch R, Tsokos GC. IL-2 protects lupus-prone mice from multiple end-organ damage by limiting CD4-CD8- IL-17-producing T cells. Journal of Immunology (Baltimore, Md. : 1950). 193: 2168-77. PMID 25063876 DOI: 10.4049/Jimmunol.1400977  0.555
2014 Spidale NA, Wang B, Tisch R. Cutting edge: Antigen-specific thymocyte feedback regulates homeostatic thymic conventional dendritic cell maturation Journal of Immunology. 193: 21-25. PMID 24890722 DOI: 10.4049/Jimmunol.1400321  0.451
2013 He Q, Morillon YM, Spidale NA, Kroger CJ, Liu B, Sartor RB, Wang B, Tisch R. Thymic development of autoreactive T cells in NOD mice is regulated in an age-dependent manner. Journal of Immunology (Baltimore, Md. : 1950). 191: 5858-66. PMID 24198282 DOI: 10.4049/Jimmunol.1302273  0.635
2013 Johnson MC, Garland AL, Nicolson SC, Li C, Samulski RJ, Wang B, Tisch R. β-cell-specific IL-2 therapy increases islet Foxp3+Treg and suppresses type 1 diabetes in NOD mice. Diabetes. 62: 3775-84. PMID 23884888 DOI: 10.2337/Db13-0669  0.816
2013 Martin A, Tisch RM, Getts DR. Manipulating T cell-mediated pathology: targets and functions of monoclonal antibody immunotherapy. Clinical Immunology (Orlando, Fla.). 148: 136-47. PMID 23688653 DOI: 10.1016/J.Clim.2013.04.011  0.473
2013 He Y, Weinberg MS, Hirsch M, Johnson MC, Tisch R, Samulski RJ, Li C. Kinetics of adeno-associated virus serotype 2 (AAV2) and AAV8 capsid antigen presentation in vivo are identical. Human Gene Therapy. 24: 545-53. PMID 23534873 DOI: 10.1089/Hum.2013.065  0.462
2012 Diz R, Garland A, Vincent BG, Johnson MC, Spidale N, Wang B, Tisch R. Autoreactive effector/memory CD4+ and CD8+ T cells infiltrating grafted and endogenous islets in diabetic NOD mice exhibit similar T cell receptor usage. Plos One. 7: e52054. PMID 23251685 DOI: 10.1371/Journal.Pone.0052054  0.838
2012 Yi Z, Li L, Garland A, He Q, Wang H, Katz JD, Tisch R, Wang B. IFN-γ receptor deficiency prevents diabetes induction by diabetogenic CD4+, but not CD8+, T cells. European Journal of Immunology. 42: 2010-8. PMID 22865049 DOI: 10.1002/Eji.201142374  0.851
2012 Yi Z, Diz R, Martin AJ, Morillon YM, Kline DE, Li L, Wang B, Tisch R. Long-term remission of diabetes in NOD mice is induced by nondepleting anti-CD4 and anti-CD8 antibodies. Diabetes. 61: 2871-80. PMID 22751694 DOI: 10.2337/Db12-0098  0.579
2011 Liblau RS, Wekerle H, Tisch RM. Cumulative autoimmunity: T cell clones recognizing several self-epitopes exhibit enhanced pathogenicity. Frontiers in Immunology. 2: 47. PMID 22566837 DOI: 10.3389/Fimmu.2011.00047  0.428
2011 Goudy KS, Johnson MC, Garland A, Li C, Samulski RJ, Wang B, Tisch R. Reduced IL-2 expression in NOD mice leads to a temporal increase in CD62Llo FoxP3+ CD4+ T cells with limited suppressor activity. European Journal of Immunology. 41: 1480-90. PMID 21469091 DOI: 10.1002/Eji.201040890  0.809
2011 Goudy KS, Johnson MC, Garland A, Li C, Samulski RJ, Wang B, Tisch R. Inducible adeno-associated virus-mediated IL-2 gene therapy prevents autoimmune diabetes. Journal of Immunology (Baltimore, Md. : 1950). 186: 3779-86. PMID 21317396 DOI: 10.4049/Jimmunol.1001422  0.812
2011 Johnson MC, Wang B, Tisch R. Genetic vaccination for re-establishing T-cell tolerance in type 1 diabetes. Human Vaccines. 7: 27-36. PMID 21157183 DOI: 10.4161/Hv.7.1.12848  0.509
2010 Kroger CJ, Flores RR, Morillon M, Wang B, Tisch R. Dysregulation of thymic clonal deletion and the escape of autoreactive T cells. Archivum Immunologiae Et Therapiae Experimentalis. 58: 449-57. PMID 20872284 DOI: 10.1007/S00005-010-0100-3  0.472
2010 Cowherd RB, Cowerd RB, Asmar MM, Alderman JM, Alderman EA, Garland AL, Busby WH, Bodnar WM, Rusyn I, Medoff BD, Tisch R, Mayer-Davis E, Swenberg JA, Zeisel SH, Combs TP. Adiponectin lowers glucose production by increasing SOGA. The American Journal of Pathology. 177: 1936-45. PMID 20813965 DOI: 10.2353/Ajpath.2010.100363  0.753
2010 Tisch R. Immunogenic versus tolerogenic dendritic cells: A matter of maturation International Reviews of Immunology. 29: 111-118. PMID 20367138 DOI: 10.3109/08830181003602515  0.375
2010 Burton AR, Baquet Z, Eisenbarth GS, Tisch R, Smeyne R, Workman CJ, Vignali DA. Central nervous system destruction mediated by glutamic acid decarboxylase-specific CD4+ T cells. Journal of Immunology (Baltimore, Md. : 1950). 184: 4863-70. PMID 20348424 DOI: 10.4049/Jimmunol.0903728  0.573
2010 Vincent BG, Young EF, Buntzman AS, Stevens R, Kepler TB, Tisch RM, Frelinger JA, Hess PR. Toxin-coupled MHC class I tetramers can specifically ablate autoreactive CD8+ T cells and delay diabetes in nonobese diabetic mice. Journal of Immunology (Baltimore, Md. : 1950). 184: 4196-204. PMID 20220085 DOI: 10.4049/Jimmunol.0903931  0.629
2009 Li L, He Q, Garland A, Yi Z, Aybar LT, Kepler TB, Frelinger JA, Wang B, Tisch R. beta cell-specific CD4+ T cell clonotypes in peripheral blood and the pancreatic islets are distinct. Journal of Immunology (Baltimore, Md. : 1950). 183: 7585-91. PMID 19917704 DOI: 10.4049/Jimmunol.0901587  0.842
2009 Young EF, Hess PR, Arnold LW, Tisch R, Frelinger JA. Islet lymphocyte subsets in male and female NOD mice are qualitatively similar but quantitatively distinct. Autoimmunity. 42: 678-91. PMID 19886740 DOI: 10.3109/08916930903213993  0.518
2009 Li L, Yi Z, Wang B, Tisch R. Suppression of ongoing T cell-mediated autoimmunity by peptide-MHC class II dimer vaccination Journal of Immunology. 183: 4809-4816. PMID 19752238 DOI: 10.4049/Jimmunol.0901616  0.547
2009 Yi Z, Li L, Matsushima GK, Earp HS, Wang B, Tisch R. A novel role for c-Src and STAT3 in apoptotic cell-mediated MerTK-dependent immunoregulation of dendritic cells. Blood. 114: 3191-8. PMID 19667404 DOI: 10.1182/Blood-2009-03-207522  0.341
2009 Pang S, Zhang L, Wang H, Yi Z, Li L, Gao L, Zhao J, Tisch R, Katz JD, Wang B. CD8(+) T cells specific for beta cells encounter their cognate antigens in the islets of NOD mice. European Journal of Immunology. 39: 2716-24. PMID 19658094 DOI: 10.1002/Eji.200939408  0.601
2009 Li C, Goudy K, Hirsch M, Asokan A, Fan Y, Alexander J, Sun J, Monahan P, Seiber D, Sidney J, Sette A, Tisch R, Frelinger J, Samulski RJ. Cellular immune response to cryptic epitopes during therapeutic gene transfer. Proceedings of the National Academy of Sciences of the United States of America. 106: 10770-4. PMID 19541644 DOI: 10.1073/Pnas.0902269106  0.761
2009 Li C, Hirsch M, DiPrimio N, Asokan A, Goudy K, Tisch R, Samulski RJ. Cytotoxic-T-lymphocyte-mediated elimination of target cells transduced with engineered adeno-associated virus type 2 vector in vivo. Journal of Virology. 83: 6817-24. PMID 19369348 DOI: 10.1128/Jvi.00278-09  0.795
2009 Gohlke PR, Williams JC, Vilen BJ, Dillon SR, Tisch R, Matsushima GK. The receptor tyrosine kinase MerTK regulates dendritic cell production of BAFF. Autoimmunity. 42: 183-97. PMID 19301199 DOI: 10.1080/08916930802668586  0.446
2009 Wallet MA, Flores RR, Wang Y, Yi Z, Kroger CJ, Mathews CE, Earp HS, Matsushima G, Wang B, Tisch R. MerTK regulates thymic selection of autoreactive T cells. Proceedings of the National Academy of Sciences of the United States of America. 106: 4810-5. PMID 19251650 DOI: 10.1073/Pnas.0900683106  0.798
2009 Tisch R, Wang B. Role of plasmacytoid dendritic cells in type 1 diabetes: Friend or foe? Diabetes. 58: 12-13. PMID 19114722 DOI: 10.2337/Db08-1341  0.58
2008 Tisch R, Wang B. Chapter 5 Dysrulation of T Cell Peripheral Tolerance in Type 1 Diabetes Advances in Immunology. 100: 125-149. PMID 19111165 DOI: 10.1016/S0065-2776(08)00805-5  0.553
2008 Wang B, Tisch R. Parameters influencing antigen-specific immunotherapy for Type 1 diabetes Immunologic Research. 42: 246-258. PMID 19052699 DOI: 10.1007/S12026-008-8090-5  0.541
2008 Li L, Yi Z, Tisch R, Wang B. Immunotherapy of type 1 diabetes Archivum Immunologiae Et Therapiae Experimentalis. 56: 227-236. PMID 18726144 DOI: 10.1007/S00005-008-0025-2  0.414
2008 Goudy KS, Wang B, Tisch R. Gene gun-mediated DNA vaccination enhances antigen-specific immunotherapy at a late preclinical stage of type 1 diabetes in nonobese diabetic mice. Clinical Immunology (Orlando, Fla.). 129: 49-57. PMID 18675592 DOI: 10.1016/J.Clim.2008.06.001  0.839
2008 Yang J, Bautz DJ, Lionaki S, Hogan SL, Chin H, Tisch RM, Schmitz JL, Pressler BM, Jennette JC, Falk RJ, Preston GA. ANCA patients have T cells responsive to complementary PR-3 antigen. Kidney International. 74: 1159-69. PMID 18596726 DOI: 10.1038/Ki.2008.309  0.439
2008 Wang B, Tisch R. Parameters influencing antigen-specific immunotherapy for type 1 diabetes. Immunologic Research. 41: 175-87. PMID 18543112 DOI: 10.1007/s12026-008-8020-6  0.423
2008 Li L, Wang B, Frelinger JA, Tisch R. T-cell promiscuity in autoimmune diabetes. Diabetes. 57: 2099-106. PMID 18492786 DOI: 10.2337/Db08-0383  0.538
2008 Burton AR, Vincent E, Arnold PY, Lennon GP, Smeltzer M, Li CS, Haskins K, Hutton J, Tisch RM, Sercarz EE, Santamaria P, Workman CJ, Vignali DA. On the pathogenicity of autoantigen-specific T-cell receptors. Diabetes. 57: 1321-30. PMID 18299317 DOI: 10.2337/Db07-1129  0.551
2008 Xiu Y, Wong CP, Bouaziz JD, Hamaguchi Y, Wang Y, Pop SM, Tisch RM, Tedder TF. B lymphocyte depletion by CD20 monoclonal antibody prevents diabetes in nonobese diabetic mice despite isotype-specific differences in Fc gamma R effector functions. Journal of Immunology (Baltimore, Md. : 1950). 180: 2863-75. PMID 18292508 DOI: 10.4049/Jimmunol.180.5.2863  0.838
2008 Wallet MA, Sen P, Flores RR, Wang Y, Yi Z, Huang Y, Mathews CE, Earp HS, Matsushima G, Wang B, Tisch R. MerTK is required for apoptotic cell-induced T cell tolerance. The Journal of Experimental Medicine. 205: 219-32. PMID 18195070 DOI: 10.1084/Jem.20062293  0.806
2008 Flores R, Wang B, Tisch R. The regulation of murine Natural Killer T cell cytokine production by Mer tyrosine kinase The Faseb Journal. 22: 555-555. DOI: 10.1096/Fasebj.22.2_Supplement.555  0.413
2007 Bouaziz JD, Yanaba K, Venturi GM, Wang Y, Tisch RM, Poe JC, Tedder TF. Therapeutic B cell depletion impairs adaptive and autoreactive CD4+ T cell activation in mice. Proceedings of the National Academy of Sciences of the United States of America. 104: 20878-83. PMID 18093919 DOI: 10.1073/Pnas.0709205105  0.59
2007 Moran TP, Burgents JE, Long B, Ferrer I, Jaffee EM, Tisch RM, Johnston RE, Serody JS. Alphaviral vector-transduced dendritic cells are successful therapeutic vaccines against neu-overexpressing tumors in wild-type mice. Vaccine. 25: 6604-12. PMID 17675184 DOI: 10.1016/J.Vaccine.2007.06.058  0.461
2007 Pop SM, Wong CP, He Q, Wang Y, Wallet MA, Goudy KS, Tisch R. The type and frequency of immunoregulatory CD4+ T-cells govern the efficacy of antigen-specific immunotherapy in nonobese diabetic mice. Diabetes. 56: 1395-402. PMID 17317763 DOI: 10.2337/Db06-0543  0.802
2007 Wong CP, Stevens R, Long B, Li L, Wang Y, Wallet MA, Goudy KS, Frelinger JA, Tisch R. Identical beta cell-specific CD8(+) T cell clonotypes typically reside in both peripheral blood lymphocyte and pancreatic islets. Journal of Immunology (Baltimore, Md. : 1950). 178: 1388-95. PMID 17237386 DOI: 10.4049/Jimmunol.178.3.1388  0.835
2007 Sen P, Wallet MA, Yi Z, Huang Y, Henderson M, Mathews CE, Earp HS, Matsushima G, Baldwin AS, Tisch RM. Apoptotic cells induce Mer tyrosine kinase-dependent blockade of NF-kappaB activation in dendritic cells. Blood. 109: 653-60. PMID 17008547 DOI: 10.1182/Blood-2006-04-017368  0.713
2007 Yang J, Bautz D, Smitz J, Chin H, Pressler B, Hogan S, Tisch R, Jennette JC, Falk R, Preston G. T Cell Responsiveness to Complementary PR3 Protein Supports a Pathogenic Role of Autoantigen Complementarity in PR3-ANCA Autoimmune Disease Clinical Immunology. 123: S121. DOI: 10.1016/J.Clim.2007.03.523  0.407
2006 Wang H, Nicholas MW, Conway KL, Sen P, Diz R, Tisch RM, Clarke SH. EBV latent membrane protein 2A induces autoreactive B cell activation and TLR hypersensitivity. Journal of Immunology (Baltimore, Md. : 1950). 177: 2793-802. PMID 16920914 DOI: 10.4049/Jimmunol.177.5.2793  0.39
2006 Long B, Wong CP, Wang Y, Tisch R. Lymphopenia-driven CD8(+) T cells are resistant to antigen-induced tolerance in NOD.scid mice. European Journal of Immunology. 36: 2003-12. PMID 16821236 DOI: 10.1002/Eji.200535717  0.592
2006 Wong CP, Li L, Frelinger JA, Tisch R. Early autoimmune destruction of islet grafts is associated with a restricted repertoire of IGRP-specific CD8+ T cells in diabetic nonobese diabetic mice. Journal of Immunology (Baltimore, Md. : 1950). 176: 1637-44. PMID 16424193 DOI: 10.4049/Jimmunol.176.3.1637  0.62
2006 Maile R, Pop SM, Tisch R, Collins EJ, Cairns BA, Frelinger JA. Low-avidity CD8lo T cells induced by incomplete antigen stimulation in vivo regulate naive higher avidity CD8hi T cell responses to the same antigen. European Journal of Immunology. 36: 397-410. PMID 16402405 DOI: 10.1002/Eji.200535064  0.843
2006 Wallet MA, Tisch R. Type 1 diabetes, inflammation and dendritic cells Drug Discovery Today: Disease Mechanisms. 3: 373-379. DOI: 10.1016/J.Ddmec.2006.09.007  0.786
2005 Goudy KS, Tisch R. Immunotherapy for the prevention and treatment of type 1 diabetes. International Reviews of Immunology. 24: 307-26. PMID 16318984 DOI: 10.1080/08830180500379721  0.821
2005 Wallet MA, Sen P, Tisch R. Immunoregulation of dendritic cells. Clinical Medicine & Research. 3: 166-75. PMID 16160071 DOI: 10.3121/Cmr.3.3.166  0.757
2005 Pop SM, Wong CP, Culton DA, Clarke SH, Tisch R. Single cell analysis shows decreasing FoxP3 and TGFbeta1 coexpressing CD4+CD25+ regulatory T cells during autoimmune diabetes. The Journal of Experimental Medicine. 201: 1333-46. PMID 15837817 DOI: 10.1084/Jem.20042398  0.841
2004 Bhattacharyya S, Sen P, Wallet M, Long B, Baldwin AS, Tisch R. Immunoregulation of dendritic cells by IL-10 is mediated through suppression of the PI3K/Akt pathway and of IkappaB kinase activity. Blood. 104: 1100-9. PMID 15113757 DOI: 10.1182/Blood-2003-12-4302  0.727
2003 Lamhamedi-Cherradi SE, Zheng S, Tisch RM, Chen YH. Critical roles of tumor necrosis factor-related apoptosis-inducing ligand in type 1 diabetes. Diabetes. 52: 2274-8. PMID 12941766 DOI: 10.2337/Diabetes.52.9.2274  0.433
2003 Seifarth C, Pop S, Liu B, Wong CP, Tisch R. More stringent conditions of plasmid DNA vaccination are required to protect grafted versus endogenous islets in nonobese diabetic mice Journal of Immunology. 171: 469-476. PMID 12817032 DOI: 10.4049/Jimmunol.171.1.469  0.816
2003 Sen P, Bhattacharyya S, Wallet M, Wong CP, Poligone B, Sen M, Baldwin AS, Tisch R. NF-kappa B hyperactivation has differential effects on the APC function of nonobese diabetic mouse macrophages. Journal of Immunology (Baltimore, Md. : 1950). 170: 1770-80. PMID 12574341 DOI: 10.4049/Jimmunol.170.4.1770  0.782
2002 Silveira PA, Johnson E, Chapman HD, Bui T, Tisch RM, Serreze DV. The preferential ability of B lymphocytes to act as diabetogenic APC in NOD mice depends on expression of self-antigen-specific immunoglobulin receptors. European Journal of Immunology. 32: 3657-66. PMID 12516557 DOI: 10.1002/1521-4141(200212)32:12<3657::Aid-Immu3657>3.0.Co;2-E  0.503
2002 Friedline RH, Wong CP, Steeber DA, Tedder TF, Tisch R. L-selectin is not required for T cell-mediated autoimmune diabetes. Journal of Immunology (Baltimore, Md. : 1950). 168: 2659-66. PMID 11884430 DOI: 10.4049/Jimmunol.168.6.2659  0.574
2002 Poligone B, Weaver DJ, Sen P, Baldwin AS, Tisch R. Elevated NF-kappaB activation in nonobese diabetic mouse dendritic cells results in enhanced APC function. Journal of Immunology (Baltimore, Md. : 1950). 168: 188-96. PMID 11751962 DOI: 10.4049/Jimmunol.168.1.188  0.53
2001 Kaufman DL, Tisch R, Sarvetnick N, Chatenoud L, Harrison LC, Haskins K, Quinn A, Sercarz E, Singh B, Von Herrath M, Wegmann D, Wen L, Zekzer D. Report from the 1st International NOD Mouse T-Cell Workshop and the Follow-Up Mini-Workshop Diabetes. 50: 2459-2463. PMID 11679422 DOI: 10.2337/Diabetes.50.11.2459  0.511
2001 Abdel-Motal UM, Friedline R, Poligone B, Pogue-Caley RR, Frelinger JA, Tisch R. Dendritic cell vaccination induces cross-reactive cytotoxic T lymphocytes specific for wild-type and natural variant human immunodeficiency virus type 1 epitopes in HLA-A*0201/Kb transgenic mice Clinical Immunology. 101: 51-58. PMID 11580226 DOI: 10.1006/Clim.2001.5095  0.47
2001 Weaver DJ, Poligone B, Bui T, Abdel-Motal UM, Baldwin AS, Tisch R. Dendritic cells from nonobese diabetic mice exhibit a defect in NF-kappa B regulation due to a hyperactive I kappa B kinase. Journal of Immunology (Baltimore, Md. : 1950). 167: 1461-8. PMID 11466366 DOI: 10.4049/Jimmunol.167.3.1461  0.544
2001 Weaver DJ, Liu B, Tisch R. Plasmid DNAs encoding insulin and glutamic acid decarboxylase 65 have distinct effects on the progression of autoimmune diabetes in nonobese diabetic mice. Journal of Immunology (Baltimore, Md. : 1950). 167: 586-92. PMID 11418698 DOI: 10.4049/Jimmunol.167.1.586  0.516
2001 Tisch R, Wang B, Atkinson MA, Serreze DV, Friedline R. A glutamic acid decarboxylase 65-specific Th2 cell clone immunoregulates autoimmune diabetes in nonobese diabetic mice Journal of Immunology. 166: 6925-6936. PMID 11359854 DOI: 10.4049/Jimmunol.166.11.6925  0.55
2001 Sharma AK, Kuhns JJ, Yan S, Friedline RH, Long B, Tisch R, Collins EJ. Class I Major Histocompatibility Complex Anchor Substitutions Alter the Conformation of T Cell Receptor Contacts Journal of Biological Chemistry. 276: 21443-21449. PMID 11287414 DOI: 10.1074/Jbc.M010791200  0.347
2001 Tisch R, Wang B, Weaver DJ, Liu B, Bui T, Arthos J, Serreze DV. Antigen-specific mediated suppression of β cell autoimmunity by plasmid DNA vaccination Journal of Immunology. 166: 2122-2132. PMID 11160264 DOI: 10.4049/Jimmunol.166.3.2122  0.535
2000 Wu YP, McMahon E, Kraine MR, Tisch R, Meyers A, Frelinger J, Matsushima GK, Suzuki K. Distribution and characterization of GFP(+) donor hematogenous cells in Twitcher mice after bone marrow transplantation. The American Journal of Pathology. 156: 1849-54. PMID 10854208 DOI: 10.1016/S0002-9440(10)65058-4  0.354
2000 Serody JS, Collins EJ, Tisch RM, Kuhns JJ, Frelinger JA. T cell activity after dendritic cell vaccination is dependent on both the type of antigen and the mode of delivery Journal of Immunology. 164: 4961-4967. PMID 10779807 DOI: 10.4049/Jimmunol.164.9.4961  0.367
1999 Kraine MR, Tisch RM. The role of environmental factors in insulin-dependent diabetes mellitus: An unresolved issue Environmental Health Perspectives. 107: 777-781. PMID 10502544 DOI: 10.1289/Ehp.99107S5777  0.39
1999 Kang Y, Melo M, Deng E, Tisch R, El-Amine M, Scott DW. Induction of hyporesponsiveness to intact foreign protein via retroviral-mediated gene expression: The IgG scaffold is important for induction and maintenance of immune hyporesponsiveness Proceedings of the National Academy of Sciences of the United States of America. 96: 8609-8614. PMID 10411923 DOI: 10.1073/Pnas.96.15.8609  0.357
1998 Singer SM, Tisch R, Yang XD, Sytwu HK, Liblau R, McDevitt HO. Prevention of diabetes in NOD mice by a mutated I-Ab transgene Diabetes. 47: 1570-1577. PMID 9753294 DOI: 10.2337/Diabetes.47.10.1570  0.412
1998 Tisch R, Liblau RS, Yang XD, Liblau P, McDevitt HO. Induction of GAD65-specific regulatory T-cells inhibits ongoing autoimmune diabetes in nonobese diabetic mice Diabetes. 47: 894-899. PMID 9604865 DOI: 10.2337/Diabetes.47.6.894  0.569
1997 Liblau R, Tisch R, Bercovici N, McDevitt HO. Systemic antigen in the treatment of T-cell-mediated autoimmune diseases Immunology Today. 18: 599-604. PMID 9425739 DOI: 10.1016/S0167-5699(97)01171-7  0.388
1996 Tisch R, McDevitt H. Insulin-dependent diabetes mellitus. Cell. 85: 291-7. PMID 8616883 DOI: 10.1016/S0092-8674(00)81106-X  0.518
1996 Liblau RS, Tisch R, Shokat K, Yang XD, Dumont N, Goodnow CC, Mcdevitt HO. Intravenous injection of soluble antigen induces thymic and peripheral T-cell apoptosis Proceedings of the National Academy of Sciences of the United States of America. 93: 3031-3036. PMID 8610163 DOI: 10.1073/Pnas.93.7.3031  0.524
1996 Tisch R. Insulin-dependent diabetes mellitus: T cell related autoimmune disease Annales De L'Institut Pasteur/Actualites. 7: 73-80. DOI: 10.1016/S0924-4204(97)85201-8  0.413
1994 Tisch R, McDevitt HO. Antigen-specific immunotherapy: Is it a real possibility to combat T- cell-mediated autoimmunity? Proceedings of the National Academy of Sciences of the United States of America. 91: 437-438. PMID 8290544 DOI: 10.1073/Pnas.91.2.437  0.409
1994 Gelber C, Paborsky L, Singer S, Mcateer D, Tisch R, Jolicoeur C, Buelow R, Mcdevitt H, Fathman CG. Isolation of nonobese diabetic mouse T-cells that recognize novel autoantigens involved in the early events of diabetes Diabetes. 43: 33-39. PMID 8262314  0.475
1994 Yang XD, Tisch R, Singer SM, Cao ZA, Liblau RS, Schreiber RD, McDevitt HO. Effect of tumor necrosis factor α on insulin-dependent diabetes mellitus in NOD mice. I. The early development of autoimmunity and the diabetogenic process Journal of Experimental Medicine. 180: 995-1004. PMID 8064245 DOI: 10.1084/Jem.180.3.995  0.396
1994 Tisch R, Yang XD, Liblau RS, McDevitt HO. Administering Glutamic Acid Decarboxylase to NOD Mice Prevents Diabetes Journal of Autoimmunity. 7: 845-850. PMID 7888040 DOI: 10.1006/Jaut.1994.1067  0.441
1994 Charlton B, Edwards CT, Tisch R, Fathman CG. Prevention of Diabetes and Insulitis by Neonatal Intrathymic Islet Administration in NOD Mice Journal of Autoimmunity. 7: 549-560. PMID 7840850 DOI: 10.1006/Jaut.1994.1040  0.449
1994 Liblau RS, Pearson CI, Shokat K, Tisch R, Yang XD, Mcdevitt HO. High-dose soluble antigen: Peripheral T-cell proliferation or apoptosis Immunological Reviews. 192-208. PMID 7698794 DOI: 10.1111/J.1600-065X.1994.Tb00890.X  0.331
1994 Yang XD, Michie SA, Tisch R, Karin N, Steinman L, McDevitt HO. Cell Adhesion Molecules: A Selective Therapeutic Target for Alleviation of IDDM Journal of Autoimmunity. 7: 859-864. PMID 7534080 DOI: 10.1006/Jaut.1994.1069  0.427
1994 Yang XD, Michie SA, Tisch R, Karin N, Steinman L, McDevitt HO. A predominant role of integrin α4 in the spontaneous development of autoimmune diabetes in nonobese diabetic mice Proceedings of the National Academy of Sciences of the United States of America. 91: 12604-12608. PMID 7528925 DOI: 10.1073/Pnas.91.26.12604  0.338
1993 Singer SM, Tisch R, Yang XD, Mcdevitt HO. An Abd transgene prevents diabetes in nonobese diabetic mice by inducing regulatory T cells Proceedings of the National Academy of Sciences of the United States of America. 90: 9566-9570. PMID 8415742 DOI: 10.1073/Pnas.90.20.9566  0.512
1993 Tisch R, Yang XD, Singer SM, Liblau RS, Fugger L, McDevitt HO. Immune response to glutamic acid decarboxylase correlates with insulitis in non-obese diabetic mice. Nature. 366: 72-5. PMID 8232539 DOI: 10.1038/366072A0  0.533
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