Alan D. Attie - Publications

Affiliations: 
University of Wisconsin, Madison, Madison, WI 
Area:
Biochemistry
Website:
https://biochem.wisc.edu/faculty/attie

129 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Keller MP, O'Connor C, Bitzer M, Schueler KL, Stapleton DS, Emfinger CH, Broman AT, Hodgin JB, Attie AD. Genetic analysis of obesity-induced diabetic nephropathy in BTBR mice. Diabetes. PMID 37935024 DOI: 10.2337/db23-0444  0.31
2023 Keller MP, Hawes EM, Schueler KL, Stapleton DS, Mitok KA, Simonett SP, Oeser JK, Sampson LL, Attie AD, Magnuson MA, O'Brien RM. An Enhancer Within Abcb11 Regulates G6pc2 in C57BL/6 Mouse Pancreatic Islets. Diabetes. PMID 37552875 DOI: 10.2337/db23-0215  0.328
2023 Keller MP, Hudkins KL, Shalev A, Bhatnagar S, Kebede MA, Merrins MJ, Davis DB, Alpers CE, Kimple ME, Attie AD. What the BTBR/J mouse has taught us about diabetes and diabetic complications. Iscience. 26: 107036. PMID 37360692 DOI: 10.1016/j.isci.2023.107036  0.757
2023 de Klerk E, Xiao Y, Emfinger CH, Keller MP, Berrios DI, Loconte V, Ekman AA, White KL, Cardone RL, Kibbey RG, Attie AD, Hebrok M. Loss of ZNF148 enhances insulin secretion in human pancreatic β cells. Jci Insight. 8. PMID 37288664 DOI: 10.1172/jci.insight.157572  0.3
2021 Attie AD. Recruiting a transcription factor in the liver to prevent atherosclerosis. The Journal of Clinical Investigation. 131. PMID 34779409 DOI: 10.1172/JCI154677  0.319
2019 Kemis JH, Linke V, Barrett KL, Boehm FJ, Traeger LL, Keller MP, Rabaglia ME, Schueler KL, Stapleton DS, Gatti DM, Churchill GA, Amador-Noguez D, Russell JD, Yandell BS, Broman KW, ... ... Attie AD, et al. Genetic determinants of gut microbiota composition and bile acid profiles in mice. Plos Genetics. 15: e1008073. PMID 31465442 DOI: 10.1371/Journal.Pgen.1008073  0.339
2019 Gupta RK, Attie AD. Thematic Review Series:  Adipose Biology. Journal of Lipid Research. PMID 31413067 DOI: 10.1194/Jlr.In119000337  0.348
2019 Keller MP, Rabaglia ME, Schueler KL, Stapleton DS, Gatti DM, Vincent M, Mitok KA, Wang Z, Ishimura T, Simonett SP, Emfinger CH, Das R, Beck T, Kendziorski C, Broman KW, ... ... Attie AD, et al. Gene loci associated with insulin secretion in islets from non-diabetic mice. The Journal of Clinical Investigation. 130. PMID 31343992 DOI: 10.1172/Jci129143  0.492
2018 Keller MP, Gatti DM, Schueler KL, Rabaglia ME, Stapleton DS, Simecek P, Vincent M, Allen S, Broman AT, Bacher R, Kendziorski C, Broman KW, Yandell BS, Churchill GA, Attie AD. Genetic Drivers of Pancreatic Islet Function. Genetics. PMID 29567659 DOI: 10.1534/Genetics.118.300864  0.447
2018 Mitok KA, Freiberger EC, Schueler KL, Rabaglia ME, Stapleton DS, Kwiecien NW, Malec PA, Hebert AS, Broman AT, Kennedy RT, Keller MP, Coon JJ, Attie AD. Islet proteomics reveals genetic variation in dopamine production resulting in altered insulin secretion. The Journal of Biological Chemistry. PMID 29496998 DOI: 10.1074/Jbc.Ra117.001102  0.432
2018 Ye R, Gordillo R, Shao M, Onodera T, Chen Z, Chen S, Lin X, SoRelle JA, Li X, Tang M, Keller MP, Kuliawat R, Attie AD, Gupta RK, Holland WL, et al. Intracellular lipid metabolism impairs β cell compensation during diet-induced obesity. The Journal of Clinical Investigation. PMID 29457786 DOI: 10.1172/Jci97702  0.456
2017 Yu Q, Canales A, Glover MS, Das R, Shi X, Liu Y, Keller MP, Attie AD, Li L. Targeted Mass Spectrometry Approach Enabled Discovery of O-Glycosylated Insulin and Related Signaling Peptides in Mouse and Human Pancreatic Islets. Analytical Chemistry. 89: 9184-9191. PMID 28726377 DOI: 10.1021/Acs.Analchem.7B01926  0.322
2017 Kreznar JH, Keller MP, Traeger LL, Rabaglia ME, Schueler KL, Stapleton DS, Zhao W, Vivas EI, Yandell BS, Broman AT, Hagenbuch B, Attie AD, Rey FE. Host Genotype and Gut Microbiome Modulate Insulin Secretion and Diet-Induced Metabolic Phenotypes. Cell Reports. 18: 1739-1750. PMID 28199845 DOI: 10.1016/J.Celrep.2017.01.062  0.394
2017 Attie AD, Churchill GA, Nadeau JH. How mice are indispensable for understanding obesity and diabetes genetics. Current Opinion in Endocrinology, Diabetes, and Obesity. 24: 83-91. PMID 28107248 DOI: 10.1097/Med.0000000000000321  0.343
2016 Keller MP, Paul PK, Rabaglia ME, Stapleton DS, Schueler KL, Broman AT, Ye SI, Leng N, Brandon CJ, Neto EC, Plaisier CL, Simonett SP, Kebede MA, Sheynkman GM, Klein MA, ... ... Attie AD, et al. The Transcription Factor Nfatc2 Regulates β-Cell Proliferation and Genes Associated with Type 2 Diabetes in Mouse and Human Islets. Plos Genetics. 12: e1006466. PMID 27935966 DOI: 10.1371/Journal.Pgen.1006466  0.434
2016 Chennamsetty I, Coronado M, Contrepois K, Keller MP, Carcamo-Orive I, Sandin J, Fajardo G, Whittle AJ, Fathzadeh M, Snyder M, Reaven G, Attie AD, Bernstein D, Quertermous T, Knowles JW. Nat1 Deficiency Is Associated with Mitochondrial Dysfunction and Exercise Intolerance in Mice. Cell Reports. 17: 527-540. PMID 27705799 DOI: 10.1016/J.Celrep.2016.09.005  0.344
2016 Baughman JM, Rose CM, Kolumam G, Webster JD, Wilkerson EM, Merrill AE, Rhoads TW, Noubade R, Katavolos P, Lesch J, Stapleton DS, Rabaglia ME, Schueler KL, Asuncion R, Domeyer M, ... ... Attie AD, et al. NeuCode Proteomics Reveals Bap1 Regulation of Metabolism. Cell Reports. 16: 583-595. PMID 27373151 DOI: 10.1016/J.Celrep.2016.05.096  0.374
2016 Knight EM, Ruiz HH, Kim SH, Harte JC, Hsieh W, Glabe C, Klein WL, Attie AD, Buettner C, Ehrlich ME, Gandy S. Unexpected partial correction of metabolic and behavioral phenotypes of Alzheimer's APP/PSEN1 mice by gene targeting of diabetes/Alzheimer's-related Sorcs1. Acta Neuropathologica Communications. 4: 16. PMID 26916443 DOI: 10.1186/S40478-016-0282-Y  0.398
2016 Tian J, Keller MP, Broman AT, Kendziorski C, Yandell BS, Attie AD, Broman KW. The Dissection of Expression Quantitative Trait Locus Hotspots. Genetics. 202: 1563-74. PMID 26837753 DOI: 10.1534/Genetics.115.183624  0.303
2015 Attie AD. How do reducing equivalents increase insulin secretion? The Journal of Clinical Investigation. 125: 3754-6. PMID 26389672 DOI: 10.1172/Jci84011  0.411
2015 Tian J, Keller MP, Oler AT, Rabaglia ME, Schueler KL, Stapleton DS, Broman AT, Zhao W, Kendziorski C, Yandell BS, Hagenbuch B, Broman KW, Attie AD. Identification of the Bile Acid Transporter Slco1a6 as a Candidate Gene That Broadly Affects Gene Expression in Mouse Pancreatic Islets. Genetics. 201: 1253-62. PMID 26385979 DOI: 10.1534/Genetics.115.179432  0.373
2015 Shang J, Li J, Keller MP, Hohmeier HE, Wang Y, Feng Y, Zhou HH, Shen X, Rabaglia M, Soni M, Attie AD, Newgard CB, Thornberry NA, Howard AD, Zhou YP. Induction of miR-132 and miR-212 Expression by Glucagon-Like Peptide 1 (GLP-1) in Rodent and Human Pancreatic β-Cells. Molecular Endocrinology (Baltimore, Md.). 29: 1243-53. PMID 26218441 DOI: 10.1210/Me.2014-1335  0.312
2014 Kebede MA, Oler AT, Gregg T, Balloon AJ, Johnson A, Mitok K, Rabaglia M, Schueler K, Stapleton D, Thorstenson C, Wrighton L, Floyd BJ, Richards O, Raines S, Eliceiri K, ... ... Attie AD, et al. SORCS1 is necessary for normal insulin secretory granule biogenesis in metabolically stressed β cells. The Journal of Clinical Investigation. 124: 4240-56. PMID 25157818 DOI: 10.1172/Jci74072  0.829
2014 Kebede MA, Attie AD. Insights into obesity and diabetes at the intersection of mouse and human genetics. Trends in Endocrinology and Metabolism: Tem. 25: 493-501. PMID 25034129 DOI: 10.1016/J.Tem.2014.06.006  0.448
2014 Bhatnagar S, Soni MS, Wrighton LS, Hebert AS, Zhou AS, Paul PK, Gregg T, Rabaglia ME, Keller MP, Coon JJ, Attie AD. Phosphorylation and degradation of tomosyn-2 de-represses insulin secretion. The Journal of Biological Chemistry. 289: 25276-86. PMID 25002582 DOI: 10.1074/Jbc.M114.575985  0.388
2014 Soni MS, Rabaglia ME, Bhatnagar S, Shang J, Ilkayeva O, Mynatt R, Zhou YP, Schadt EE, Thornberry NA, Muoio DM, Keller MP, Attie AD. Downregulation of carnitine acyl-carnitine translocase by miRNAs 132 and 212 amplifies glucose-stimulated insulin secretion. Diabetes. 63: 3805-14. PMID 24969106 DOI: 10.2337/Db13-1677  0.352
2014 Ulbrich A, Merrill AE, Hebert AS, Westphall MS, Keller MP, Attie AD, Coon JJ. Neutron-encoded protein quantification by peptide carbamylation. Journal of the American Society For Mass Spectrometry. 25: 6-9. PMID 24178922 DOI: 10.1007/S13361-013-0765-Z  0.304
2013 O'Halloran TV, Kebede M, Philips SJ, Attie AD. Zinc, insulin, and the liver: a ménage à trois. The Journal of Clinical Investigation. 123: 4136-9. PMID 24051373 DOI: 10.1172/Jci72325  0.392
2013 Haas ME, Attie AD, Biddinger SB. The regulation of ApoB metabolism by insulin. Trends in Endocrinology and Metabolism: Tem. 24: 391-7. PMID 23721961 DOI: 10.1016/J.Tem.2013.04.001  0.465
2013 Kimple ME, Keller MP, Rabaglia MR, Pasker RL, Neuman JC, Truchan NA, Brar HK, Attie AD. Prostaglandin E2 receptor, EP3, is induced in diabetic islets and negatively regulates glucose- and hormone-stimulated insulin secretion. Diabetes. 62: 1904-12. PMID 23349487 DOI: 10.2337/Db12-0769  0.453
2012 Tu Z, Keller MP, Zhang C, Rabaglia ME, Greenawalt DM, Yang X, Wang IM, Dai H, Bruss MD, Lum PY, Zhou YP, Kemp DM, Kendziorski C, Yandell BS, Attie AD, et al. Integrative analysis of a cross-loci regulation network identifies App as a gene regulating insulin secretion from pancreatic islets. Plos Genetics. 8: e1003107. PMID 23236292 DOI: 10.1371/Journal.Pgen.1003107  0.503
2012 Grimsrud PA, Carson JJ, Hebert AS, Hubler SL, Niemi NM, Bailey DJ, Jochem A, Stapleton DS, Keller MP, Westphall MS, Yandell BS, Attie AD, Coon JJ, Pagliarini DJ. A quantitative map of the liver mitochondrial phosphoproteome reveals posttranslational control of ketogenesis. Cell Metabolism. 16: 672-83. PMID 23140645 DOI: 10.1016/J.Cmet.2012.10.004  0.324
2012 Wang CY, Stapleton DS, Schueler KL, Rabaglia ME, Oler AT, Keller MP, Kendziorski CM, Broman KW, Yandell BS, Schadt EE, Attie AD. Tsc2, a positional candidate gene underlying a quantitative trait locus for hepatic steatosis. Journal of Lipid Research. 53: 1493-501. PMID 22628617 DOI: 10.1194/Jlr.M025239  0.467
2012 Casellas J, Gularte RJ, Farber CR, Varona L, Mehrabian M, Schadt EE, Lusis AJ, Attie AD, Yandell BS, Medrano JF. Genome scans for transmission ratio distortion regions in mice. Genetics. 191: 247-59. PMID 22367040 DOI: 10.1534/Genetics.111.135988  0.303
2011 Bhatnagar S, Oler AT, Rabaglia ME, Stapleton DS, Schueler KL, Truchan NA, Worzella SL, Stoehr JP, Clee SM, Yandell BS, Keller MP, Thurmond DC, Attie AD. Positional cloning of a type 2 diabetes quantitative trait locus; tomosyn-2, a negative regulator of insulin secretion. Plos Genetics. 7: e1002323. PMID 21998599 DOI: 10.1371/Journal.Pgen.1002323  0.831
2011 Raines SM, Richards OC, Schneider LR, Schueler KL, Rabaglia ME, Oler AT, Stapleton DS, Genové G, Dawson JA, Betsholtz C, Attie AD. Loss of PDGF-B activity increases hepatic vascular permeability and enhances insulin sensitivity. American Journal of Physiology. Endocrinology and Metabolism. 301: E517-26. PMID 21673305 DOI: 10.1152/Ajpendo.00241.2011  0.806
2011 Lane R, Attie A, Ehrlich M, Gandy S. P2-240: The diabetes associated protein, SorCS1 regulates APP metabolism Alzheimer's & Dementia. 7: S388-S389. DOI: 10.1016/J.Jalz.2011.05.1123  0.345
2010 Lavine JA, Attie AD. Gastrointestinal hormones and the regulation of β-cell mass. Annals of the New York Academy of Sciences. 1212: 41-58. PMID 21039588 DOI: 10.1111/J.1749-6632.2010.05802.X  0.784
2010 Lane RF, Raines SM, Steele JW, Ehrlich ME, Lah JA, Small SA, Tanzi RE, Attie AD, Gandy S. Diabetes-associated SorCS1 regulates Alzheimer's amyloid-beta metabolism: evidence for involvement of SorL1 and the retromer complex. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 13110-5. PMID 20881129 DOI: 10.1523/Jneurosci.3872-10.2010  0.788
2010 Attie AD, Keller MP. Gene co-expression modules and type 2 diabetes. Results and Problems in Cell Differentiation. 52: 47-56. PMID 20865371 DOI: 10.1007/978-3-642-14426-4_5  0.49
2010 Davis DB, Lavine JA, Suhonen JI, Krautkramer KA, Rabaglia ME, Sperger JM, Fernandez LA, Yandell BS, Keller MP, Wang IM, Schadt EE, Attie AD. FoxM1 is up-regulated by obesity and stimulates beta-cell proliferation. Molecular Endocrinology (Baltimore, Md.). 24: 1822-34. PMID 20660304 DOI: 10.1210/Me.2010-0082  0.814
2010 Hudkins KL, Pichaiwong W, Wietecha T, Kowalewska J, Banas MC, Spencer MW, Mühlfeld A, Koelling M, Pippin JW, Shankland SJ, Askari B, Rabaglia ME, Keller MP, Attie AD, Alpers CE. BTBR Ob/Ob mutant mice model progressive diabetic nephropathy. Journal of the American Society of Nephrology : Jasn. 21: 1533-42. PMID 20634301 DOI: 10.1681/Asn.2009121290  0.419
2010 Lavine JA, Raess PW, Stapleton DS, Rabaglia ME, Suhonen JI, Schueler KL, Koltes JE, Dawson JA, Yandell BS, Samuelson LC, Beinfeld MC, Davis DB, Hellerstein MK, Keller MP, Attie AD. Cholecystokinin is up-regulated in obese mouse islets and expands beta-cell mass by increasing beta-cell survival. Endocrinology. 151: 3577-88. PMID 20534724 DOI: 10.1210/En.2010-0233  0.791
2010 Zhong H, Beaulaurier J, Lum PY, Molony C, Yang X, Macneil DJ, Weingarth DT, Zhang B, Greenawalt D, Dobrin R, Hao K, Woo S, Fabre-Suver C, Qian S, Tota MR, ... ... Attie AD, et al. Liver and adipose expression associated SNPs are enriched for association to type 2 diabetes. Plos Genetics. 6: e1000932. PMID 20463879 DOI: 10.1371/Journal.Pgen.1000932  0.362
2010 Keller MP, Attie AD. Physiological insights gained from gene expression analysis in obesity and diabetes. Annual Review of Nutrition. 30: 341-64. PMID 20415584 DOI: 10.1146/Annurev.Nutr.012809.104747  0.479
2010 Newgard CB, Attie AD. Getting biological about the genetics of diabetes. Nature Medicine. 16: 388-91. PMID 20376050 DOI: 10.1038/Nm0410-388  0.321
2010 Richards OC, Raines SM, Attie AD. The role of blood vessels, endothelial cells, and vascular pericytes in insulin secretion and peripheral insulin action. Endocrine Reviews. 31: 343-63. PMID 20164242 DOI: 10.1210/Er.2009-0035  0.805
2010 Lavine JA, Raess PW, Davis DB, Rabaglia ME, Presley BK, Keller MP, Beinfeld MC, Kopin AS, Newgard CB, Attie AD. Contamination with E1A-positive wild-type adenovirus accounts for species-specific stimulation of islet cell proliferation by CCK: a cautionary note. Molecular Endocrinology (Baltimore, Md.). 24: 464-7. PMID 20081104 DOI: 10.1210/Me.2009-0384  0.772
2010 Davis DB, Lavine JA, Suhonen JI, Krautkramer KA, Rabaglia ME, Sperger JM, Fernandez LA, Yandell BS, Keller MP, Wang I, Schadt EE, Attie AD. FoxM1 Is Up-Regulated by Obesity and Stimulates β-Cell Proliferation The Journal of Clinical Endocrinology & Metabolism. 95: 4084-4084. DOI: 10.1210/Jcem.95.8.9994  0.773
2010 Lane RF, Raines SM, Levey A, Lah JJ, Small SA, Tanzi RE, Attie AD, Gandy SE. Diabetes-linked SORCS1, a gamma-secretase substrate and regulator of Alzheimer APP metabolism, forms complexes with multiple Alzheimer-linked proteins (APP, PS1, BACE, VPS35, and SORLA) Alzheimers & Dementia. 6. DOI: 10.1016/J.Jalz.2010.05.814  0.782
2009 Zhao E, Keller MP, Rabaglia ME, Oler AT, Stapleton DS, Schueler KL, Neto EC, Moon JY, Wang P, Wang IM, Lum PY, Ivanovska I, Cleary M, Greenawalt D, Tsang J, ... ... Attie AD, et al. Obesity and genetics regulate microRNAs in islets, liver, and adipose of diabetic mice. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 20: 476-85. PMID 19727952 DOI: 10.1007/S00335-009-9217-2  0.377
2009 Rieck S, White P, Schug J, Fox AJ, Smirnova O, Gao N, Gupta RK, Wang ZV, Scherer PE, Keller MP, Attie AD, Kaestner KH. The transcriptional response of the islet to pregnancy in mice. Molecular Endocrinology (Baltimore, Md.). 23: 1702-12. PMID 19574445 DOI: 10.1210/Me.2009-0144  0.437
2009 Halberg N, Khan T, Trujillo ME, Wernstedt-Asterholm I, Attie AD, Sherwani S, Wang ZV, Landskroner-Eiger S, Dineen S, Magalang UJ, Brekken RA, Scherer PE. Hypoxia-inducible factor 1alpha induces fibrosis and insulin resistance in white adipose tissue. Molecular and Cellular Biology. 29: 4467-83. PMID 19546236 DOI: 10.1128/Mcb.00192-09  0.335
2009 Attie AD, Scherer PE. Adipocyte metabolism and obesity. Journal of Lipid Research. 50: S395-9. PMID 19017614 DOI: 10.1194/Jlr.R800057-Jlr200  0.373
2008 Lusis AJ, Attie AD, Reue K. Metabolic syndrome: from epidemiology to systems biology. Nature Reviews. Genetics. 9: 819-30. PMID 18852695 DOI: 10.1038/Nrg2468  0.314
2008 Lavine JA, Raess PW, Davis DB, Rabaglia ME, Presley BK, Keller MP, Beinfeld MC, Kopin AS, Newgard CB, Attie AD. Overexpression of pre-pro-cholecystokinin stimulates beta-cell proliferation in mouse and human islets with retention of islet function. Molecular Endocrinology (Baltimore, Md.). 22: 2716-28. PMID 18845673 DOI: 10.1210/Me.2008-0255  0.792
2008 Chen J, Hui ST, Couto FM, Mungrue IN, Davis DB, Attie AD, Lusis AJ, Davis RA, Shalev A. Thioredoxin-interacting protein deficiency induces Akt/Bcl-xL signaling and pancreatic beta-cell mass and protects against diabetes. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 22: 3581-94. PMID 18552236 DOI: 10.1096/Fj.08-111690  0.782
2008 Flowers MT, Keller MP, Choi Y, Lan H, Kendziorski C, Ntambi JM, Attie AD. Liver gene expression analysis reveals endoplasmic reticulum stress and metabolic dysfunction in SCD1-deficient mice fed a very low-fat diet. Physiological Genomics. 33: 361-72. PMID 18381840 DOI: 10.1152/Physiolgenomics.00139.2007  0.728
2008 Ferrara CT, Wang P, Neto EC, Stevens RD, Bain JR, Wenner BR, Ilkayeva OR, Keller MP, Blasiole DA, Kendziorski C, Yandell BS, Newgard CB, Attie AD. Genetic networks of liver metabolism revealed by integration of metabolic and transcriptional profiling. Plos Genetics. 4: e1000034. PMID 18369453 DOI: 10.1371/Journal.Pgen.1000034  0.8
2008 Keller MP, Choi Y, Wang P, Davis DB, Rabaglia ME, Oler AT, Stapleton DS, Argmann C, Schueler KL, Edwards S, Steinberg HA, Chaibub Neto E, Kleinhanz R, Turner S, Hellerstein MK, ... ... Attie AD, et al. A gene expression network model of type 2 diabetes links cell cycle regulation in islets with diabetes susceptibility. Genome Research. 18: 706-16. PMID 18347327 DOI: 10.1101/Gr.074914.107  0.81
2008 Oler AT, Attie AD. A rapid, microplate SNP genotype assay for the leptinob allele. Journal of Lipid Research. 49: 1126-9. PMID 18272929 DOI: 10.1194/Jlr.D800002-Jlr200  0.315
2008 Blasiole DA, Oler AT, Attie AD. Regulation of ApoB secretion by the low density lipoprotein receptor requires exit from the endoplasmic reticulum and interaction with ApoE or ApoB. The Journal of Biological Chemistry. 283: 11374-81. PMID 18272520 DOI: 10.1074/Jbc.M710457200  0.79
2008 Ferrara CT, Wang P, Neto EC, Stevens RD, Bain JR, Wenner BR, Ilkayeva OR, Keller MP, Blasiole DA, Kendziorski C, Yandell BS, Newgard CB, Attie AD. Correction: Genetic Networks of Liver Metabolism Revealed by Integration of Metabolic and Transcriptional Profiling Plos Genetics. 4. DOI: 10.1371/annotation/7989839d-0677-4f59-a218-f4ebb6fd0b66  0.766
2007 Attie AD, Flowers MT, Flowers JB, Groen AK, Kuipers F, Ntambi JM. Stearoyl-CoA desaturase deficiency, hypercholesterolaemia, cholestasis and diabetes. Novartis Foundation Symposium. 286: 47-53; discussion 54. PMID 18269173 DOI: 10.1002/9780470985571.Ch5  0.823
2007 Attie AD. High-maintenance proteins and hypertriglyceridemia. Nature Genetics. 39: 1424-5. PMID 18046326 DOI: 10.1038/Ng1207-1424  0.315
2007 Blasiole DA, Davis RA, Attie AD. The physiological and molecular regulation of lipoprotein assembly and secretion. Molecular Biosystems. 3: 608-19. PMID 17700861 DOI: 10.1039/B700706J  0.779
2007 Attie AD, Flowers MT, Flowers JB, Groen AK, Kuipers F, Ntambi JM. Stearoyl-CoA desaturase deficiency, hypercholesterolemia, cholestasis, and diabetes. Nutrition Reviews. 65: S35-8. PMID 17605312 DOI: 10.1111/J.1753-4887.2007.Tb00326.X  0.814
2007 Nassoury N, Blasiole DA, Tebon Oler A, Benjannet S, Hamelin J, Poupon V, McPherson PS, Attie AD, Prat A, Seidah NG. The cellular trafficking of the secretory proprotein convertase PCSK9 and its dependence on the LDLR. Traffic (Copenhagen, Denmark). 8: 718-32. PMID 17461796 DOI: 10.1111/J.1600-0854.2007.00562.X  0.785
2007 Goodarzi MO, Lehman DM, Taylor KD, Guo X, Cui J, Quiñones MJ, Clee SM, Yandell BS, Blangero J, Hsueh WA, Attie AD, Stern MP, Rotter JI. SORCS1: a novel human type 2 diabetes susceptibility gene suggested by the mouse. Diabetes. 56: 1922-9. PMID 17426289 DOI: 10.2337/Db06-1677  0.476
2007 Flowers JB, Rabaglia ME, Schueler KL, Flowers MT, Lan H, Keller MP, Ntambi JM, Attie AD. Loss of stearoyl-CoA desaturase-1 improves insulin sensitivity in lean mice but worsens diabetes in leptin-deficient obese mice. Diabetes. 56: 1228-39. PMID 17369521 DOI: 10.2337/Db06-1142  0.835
2007 Attie AD. ABCA1: at the nexus of cholesterol, HDL and atherosclerosis. Trends in Biochemical Sciences. 32: 172-9. PMID 17324574 DOI: 10.1016/J.Tibs.2007.02.001  0.301
2007 Flowers JB, Oler AT, Nadler ST, Choi Y, Schueler KL, Yandell BS, Kendziorski CM, Attie AD. Abdominal obesity in BTBR male mice is associated with peripheral but not hepatic insulin resistance. American Journal of Physiology. Endocrinology and Metabolism. 292: E936-45. PMID 17132824 DOI: 10.1152/Ajpendo.00370.2006  0.804
2007 Clee SM, Attie AD. The genetic landscape of type 2 diabetes in mice. Endocrine Reviews. 28: 48-83. PMID 17018838 DOI: 10.1210/Er.2006-0035  0.478
2006 Flowers MT, Groen AK, Oler AT, Keller MP, Choi Y, Schueler KL, Richards OC, Lan H, Miyazaki M, Kuipers F, Kendziorski CM, Ntambi JM, Attie AD. Cholestasis and hypercholesterolemia in SCD1-deficient mice fed a low-fat, high-carbohydrate diet. Journal of Lipid Research. 47: 2668-80. PMID 17005996 DOI: 10.1194/Jlr.M600203-Jlr200  0.794
2006 Clee SM, Yandell BS, Schueler KM, Rabaglia ME, Richards OC, Raines SM, Kabara EA, Klass DM, Mui ET, Stapleton DS, Gray-Keller MP, Young MB, Stoehr JP, Lan H, Boronenkov I, ... ... Attie AD, et al. Positional cloning of Sorcs1, a type 2 diabetes quantitative trait locus. Nature Genetics. 38: 688-93. PMID 16682971 DOI: 10.1038/Ng1796  0.797
2006 Attie AD. A liver-high-density lipoprotein-ovarian axis of fertility. Endocrinology. 147: 1575-6. PMID 16543376 DOI: 10.1210/En.2006-0093  0.352
2006 Kendziorski CM, Chen M, Yuan M, Lan H, Attie AD. Statistical methods for expression quantitative trait loci (eQTL) mapping. Biometrics. 62: 19-27. PMID 16542225 DOI: 10.1111/J.1541-0420.2005.00437.X  0.316
2006 Lan H, Chen M, Flowers JB, Yandell BS, Stapleton DS, Mata CM, Mui ET, Flowers MT, Schueler KL, Manly KF, Williams RW, Kendziorski C, Attie AD. Combined expression trait correlations and expression quantitative trait locus mapping. Plos Genetics. 2: e6. PMID 16424919 DOI: 10.1371/Journal.Pgen.0020006  0.785
2005 Clee SM, Nadler ST, Attie AD. Genetic and genomic studies of the BTBR ob/ob mouse model of type 2 diabetes. American Journal of Therapeutics. 12: 491-8. PMID 16280642 DOI: 10.1097/01.Mjt.0000178781.89789.25  0.834
2005 Attie AD, Seidah NG. Dual regulation of the LDL receptor--some clarity and new questions. Cell Metabolism. 1: 290-2. PMID 16054075 DOI: 10.1016/J.Cmet.2005.04.006  0.32
2005 Rabaglia ME, Gray-Keller MP, Frey BL, Shortreed MR, Smith LM, Attie AD. Alpha-Ketoisocaproate-induced hypersecretion of insulin by islets from diabetes-susceptible mice. American Journal of Physiology. Endocrinology and Metabolism. 289: E218-24. PMID 15741243 DOI: 10.1152/Ajpendo.00573.2004  0.424
2005 Minn AH, Lan H, Rabaglia ME, Harlan DM, Peculis BA, Attie AD, Shalev A. Increased insulin translation from an insulin splice-variant overexpressed in diabetes, obesity, and insulin resistance. Molecular Endocrinology (Baltimore, Md.). 19: 794-803. PMID 15550470 DOI: 10.1210/Me.2004-0119  0.473
2005 Sheth SS, Castellani LW, Chari S, Wagg C, Thipphavong CK, Bodnar JS, Tontonoz P, Attie AD, Lopaschuk GD, Lusis AJ. Thioredoxin-interacting protein deficiency disrupts the fasting-feeding metabolic transition. Journal of Lipid Research. 46: 123-34. PMID 15520447 DOI: 10.1194/Jlr.M400341-Jlr200  0.395
2004 Benjannet S, Rhainds D, Essalmani R, Mayne J, Wickham L, Jin W, Asselin MC, Hamelin J, Varret M, Allard D, Trillard M, Abifadel M, Tebon A, Attie AD, Rader DJ, et al. NARC-1/PCSK9 and its natural mutants: zymogen cleavage and effects on the low density lipoprotein (LDL) receptor and LDL cholesterol. The Journal of Biological Chemistry. 279: 48865-75. PMID 15358785 DOI: 10.1074/Jbc.M409699200  0.365
2004 Attie AD. The mystery of PCSK9. Arteriosclerosis, Thrombosis, and Vascular Biology. 24: 1337-9. PMID 15297287 DOI: 10.1161/01.Atv.0000137288.82390.04  0.354
2004 Attie AD. Insig: a significant integrator of nutrient and hormonal signals. The Journal of Clinical Investigation. 113: 1112-4. PMID 15085189 DOI: 10.1172/Jci21450  0.426
2004 Hui TY, Sheth SS, Diffley JM, Potter DW, Lusis AJ, Attie AD, Davis RA. Mice lacking thioredoxin-interacting protein provide evidence linking cellular redox state to appropriate response to nutritional signals. The Journal of Biological Chemistry. 279: 24387-93. PMID 15047687 DOI: 10.1074/Jbc.M401280200  0.469
2004 Stoehr JP, Byers JE, Clee SM, Lan H, Boronenkov IV, Schueler KL, Yandell BS, Attie AD. Identification of major quantitative trait loci controlling body weight variation in ob/ob mice. Diabetes. 53: 245-9. PMID 14693723 DOI: 10.2337/Diabetes.53.1.245  0.807
2004 Lan H, Rabaglia ME, Schueler KL, Mata C, Yandell BS, Attie AD. Distinguishing covariation from causation in diabetes: a lesson from the protein disulfide isomerase mRNA abundance trait. Diabetes. 53: 240-4. PMID 14693722 DOI: 10.2337/Diabetes.53.1.240  0.441
2003 Lan H, Stoehr JP, Nadler ST, Schueler KL, Yandell BS, Attie AD. Dimension reduction for mapping mRNA abundance as quantitative traits. Genetics. 164: 1607-14. PMID 12930764  0.779
2003 Attie AD, Kendziorski CM. PGC-1alpha at the crossroads of type 2 diabetes. Nature Genetics. 34: 244-5. PMID 12833045 DOI: 10.1038/Ng0703-244  0.353
2003 Lan H, Rabaglia ME, Stoehr JP, Nadler ST, Schueler KL, Zou F, Yandell BS, Attie AD. Gene expression profiles of nondiabetic and diabetic obese mice suggest a role of hepatic lipogenic capacity in diabetes susceptibility. Diabetes. 52: 688-700. PMID 12606510 DOI: 10.2337/Diabetes.52.3.688  0.817
2003 Mulligan JD, Flowers MT, Tebon A, Bitgood JJ, Wellington C, Hayden MR, Attie AD. ABCA1 is essential for efficient basolateral cholesterol efflux during the absorption of dietary cholesterol in chickens. The Journal of Biological Chemistry. 278: 13356-66. PMID 12551945 DOI: 10.1074/Jbc.M212377200  0.775
2002 Attie AD, Krauss RM, Gray-Keller MP, Brownlie A, Miyazaki M, Kastelein JJ, Lusis AJ, Stalenhoef AF, Stoehr JP, Hayden MR, Ntambi JM. Relationship between stearoyl-CoA desaturase activity and plasma triglycerides in human and mouse hypertriglyceridemia. Journal of Lipid Research. 43: 1899-907. PMID 12401889 DOI: 10.1194/Jlr.M200189-Jlr200  0.787
2002 Attie AD, Hamon Y, Brooks-Wilson AR, Gray-Keller MP, MacDonald ML, Rigot V, Tebon A, Zhang LH, Mulligan JD, Singaraja RR, Bitgood JJ, Cook ME, Kastelein JJ, Chimini G, Hayden MR. Identification and functional analysis of a naturally occurring E89K mutation in the ABCA1 gene of the WHAM chicken. Journal of Lipid Research. 43: 1610-7. PMID 12364545 DOI: 10.1194/Jlr.M200223-Jlr200  0.754
2002 Ntambi JM, Miyazaki M, Stoehr JP, Lan H, Kendziorski CM, Yandell BS, Song Y, Cohen P, Friedman JM, Attie AD. Loss of stearoyl-CoA desaturase-1 function protects mice against adiposity. Proceedings of the National Academy of Sciences of the United States of America. 99: 11482-6. PMID 12177411 DOI: 10.1073/Pnas.132384699  0.822
2002 Gillian-Daniel DL, Bates PW, Tebon A, Attie AD. Endoplasmic reticulum localization of the low density lipoprotein receptor mediates presecretory degradation of apolipoprotein B. Proceedings of the National Academy of Sciences of the United States of America. 99: 4337-42. PMID 11904390 DOI: 10.1073/Pnas.072557199  0.319
2001 Nadler ST, Stoehr JP, Rabaglia ME, Schueler KL, Birnbaum MJ, Attie AD. Normal Akt/PKB with reduced PI3K activation in insulin-resistant mice American Journal of Physiology - Endocrinology and Metabolism. 281: E1249-E1254. PMID 11701440 DOI: 10.1152/Ajpendo.2001.281.6.E1249  0.806
2001 Nadler ST, Attie AD. Please pass the chips: genomic insights into obesity and diabetes. The Journal of Nutrition. 131: 2078-81. PMID 11481397 DOI: 10.1093/Jn/131.8.2078  0.821
2000 Stoehr JP, Nadler ST, Schueler KL, Rabaglia ME, Yandell BS, Metz SA, Attie AD. Genetic obesity unmasks nonlinear interactions between murine type 2 diabetes susceptibility loci. Diabetes. 49: 1946-54. PMID 11078464 DOI: 10.2337/Diabetes.49.11.1946  0.819
2000 Nadler ST, Stoehr JP, Schueler KL, Tanimoto G, Yandell BS, Attie AD. The expression of adipogenic genes is decreased in obesity and diabetes mellitus. Proceedings of the National Academy of Sciences of the United States of America. 97: 11371-6. PMID 11027337 DOI: 10.1073/Pnas.97.21.11371  0.808
2000 Miyazaki M, Kim YC, Gray-Keller MP, Attie AD, Ntambi JM. The biosynthesis of hepatic cholesterol esters and triglycerides is impaired in mice with a disruption of the gene for stearoyl-CoA desaturase 1. The Journal of Biological Chemistry. 275: 30132-8. PMID 10899171 DOI: 10.1074/Jbc.M005488200  0.387
2000 Hayden MR, Clee SM, Brooks-Wilson A, Genest J, Attie A, Kastelein JJ. Cholesterol efflux regulatory protein, Tangier disease and familial high-density lipoprotein deficiency. Current Opinion in Lipidology. 11: 117-22. PMID 10787172 DOI: 10.1097/00041433-200004000-00003  0.31
2000 Twisk J, Gillian-Daniel DL, Tebon A, Wang L, Barrett PH, Attie AD. The role of the LDL receptor in apolipoprotein B secretion. The Journal of Clinical Investigation. 105: 521-32. PMID 10683382 DOI: 10.1172/Jci8623  0.36
1997 Ranheim T, Dumke C, Schueler KL, Cartee GD, Attie AD. Interaction between BTBR and C57BL/6J genomes produces an insulin resistance syndrome in (BTBR x C57BL/6J) F1 mice Arteriosclerosis, Thrombosis, and Vascular Biology. 17: 3286-3293. PMID 9409324 DOI: 10.1161/01.Atv.17.11.3286  0.44
1997 Wang L, Fast DG, Attie AD. The enzymatic and non-enzymatic roles of protein-disulfide isomerase in apolipoprotein B secretion. The Journal of Biological Chemistry. 272: 27644-51. PMID 9346903 DOI: 10.1074/Jbc.272.44.27644  0.319
1996 Dirlam KA, Gretch DG, LaCount DJ, Sturley SL, Attie AD. Expression and characterization of a truncated, soluble, low-density lipoprotein receptor Protein Expression and Purification. 8: 489-500. PMID 8954898 DOI: 10.1016/S1046-5928(96)90129-1  0.613
1996 Gretch DG, Sturley SL, Wang L, Lipton BA, Dunning A, Grunwald KA, Wetterau JR, Yao Z, Talmud P, Attie AD. The amino terminus of apolipoprotein B is necessary but not sufficient for microsomal triglyceride transfer protein responsiveness. The Journal of Biological Chemistry. 271: 8682-91. PMID 8621500 DOI: 10.1074/Jbc.271.15.8682  0.653
1995 Gretch DG, Sturley SL, Attie AD. Human apolipoprotein E mediates processive buoyant lipoprotein formation in insect larvae. Biochemistry. 34: 545-52. PMID 7819248 DOI: 10.1021/Bi00002A020  0.637
1995 Choi SY, Sivaram P, Walker DE, Curtiss LK, Gretch DG, Sturley SL, Attie AD, Deckelbaum RJ, Goldberg IJ. Lipoprotein lipase association with lipoproteins involves protein-protein interaction with apolipoprotein B. The Journal of Biological Chemistry. 270: 8081-6. PMID 7713910 DOI: 10.1074/Jbc.270.14.8081  0.627
1994 Aiello RJ, Nevin DN, Ebert DL, Uelmen PJ, Kaiser ME, MacCluer JW, Blangero J, Dyer TD, Attie AD. Apolipoprotein B and a second major gene locus contribute to phenotypic variation of spontaneous hypercholesterolemia in pigs Arteriosclerosis, Thrombosis, and Vascular Biology. 14: 409-419. PMID 8123646 DOI: 10.1161/01.Atv.14.3.409  0.321
1994 Sturley SL, Talmud PJ, Brasseur R, Culbertson MR, Humphries SE, Attie AD. Human apolipoprotein B signal sequence variants confer a secretion-defective phenotype when expressed in yeast. The Journal of Biological Chemistry. 269: 21670-5. PMID 8063810  0.603
1994 Schreyer SA, Hart LK, Attie AD. Hypercatabolism of lipoprotein-free apolipoprotein A-I in HDL-deficient mutant chickens. Arteriosclerosis and Thrombosis : a Journal of Vascular Biology / American Heart Association. 14: 2053-9. PMID 7981195 DOI: 10.1161/01.Atv.14.12.2053  0.331
1993 Kaiser ME, Nevin DN, Sturley SL, Purtell C, Attie AD. Determination of pig apolipoprotein B genotype by gene amplification and restriction fragment length polymorphism analysis. Animal Genetics. 24: 117-20. PMID 8101055 DOI: 10.1111/J.1365-2052.1993.Tb00251.X  0.627
1992 Poernama F, Subramanian R, Cook ME, Attie AD. High density lipoprotein deficiency syndrome in chickens is not associated with an increased susceptibility to atherosclerosis. Arteriosclerosis and Thrombosis : a Journal of Vascular Biology. 12: 601-7. PMID 1576121 DOI: 10.1161/01.Atv.12.5.601  0.308
1991 Checovich WJ, Aiello RJ, Attie AD. Overproduction of a buoyant low density lipoprotein subspecies in spontaneously hypercholesterolemic mutant pigs. Arteriosclerosis and Thrombosis : a Journal of Vascular Biology / American Heart Association. 11: 351-61. PMID 1998653 DOI: 10.1161/01.Atv.11.2.351  0.324
1991 Gretch DG, Sturley SL, Friesen PD, Beckage NE, Attie AD. Baculovirus-mediated expression of human apolipoprotein E in Manduca sexta larvae generates particles that bind to the low density lipoprotein receptor Proceedings of the National Academy of Sciences of the United States of America. 88: 8530-8533. PMID 1924311 DOI: 10.1073/Pnas.88.19.8530  0.625
1991 Sturley SL, Culbertson MR, Attie AD. Secretion and lipid association of human apolipoprotein E in Saccharomyces cerevisiae requires a host mutation in sterol esterification and uptake. The Journal of Biological Chemistry. 266: 16273-6. PMID 1885560  0.627
1988 Checovich WJ, Fitch WL, Krauss RM, Smith MP, Rapacz J, Smith CL, Attie AD. Defective catabolism and abnormal composition of low-density lipoproteins from mutant pigs with hypercholesterolemia Biochemistry. 27: 1934-1941. PMID 3378039 DOI: 10.1021/Bi00406A020  0.31
1986 Rapacz J, Hasler-Rapacz J, Taylor KM, Checovich WJ, Attie AD. Lipoprotein mutations in pigs are associated with elevated plasma cholesterol and atherosclerosis. Science (New York, N.Y.). 234: 1573-7. PMID 3787263 DOI: 10.1126/Science.3787263  0.316
1982 Pittman RC, Attie AD, Carew TE, Steinberg D. Tissue sites of catabolism of rat and human low density lipoproteins in rats. Biochimica Et Biophysica Acta. 710: 7-14. PMID 7055596 DOI: 10.1016/0005-2760(82)90183-7  0.367
1982 Pittman RC, Carew TE, Attie AD, Witztum JL, Watanabe Y, Steinberg D. Receptor-dependent and receptor-independent degradation of low density lipoprotein in normal rabbits and in receptor-deficient mutant rabbits. The Journal of Biological Chemistry. 257: 7994-8000. PMID 6282866  0.415
1982 Attie AD, Pittman RC, Steinberg D. Hepatic catabolism of low density lipoprotein: mechanisms and metabolic consequences. Hepatology (Baltimore, Md.). 2: 269-81. PMID 6279484 DOI: 10.1002/Hep.1840020215  0.381
1981 Attie AD, Pittman RC, Watanabe Y, Steinberg D. Low density lipoprotein receptor deficiency in cultured hepatocytes of the WHHL rabbit. Further evidence of two pathways for catabolism of exogenous proteins. The Journal of Biological Chemistry. 256: 9789-92. PMID 6268629  0.432
1981 Drevon CA, Attie AD, Pangburn SH, Steinberg D. Metabolism of homologous and heterologous lipoproteins by cultured rat and human skin fibroblasts. Journal of Lipid Research. 22: 37-46. PMID 6260882  0.399
1980 Attie AD, Pittman RC, Steinberg D. Metabolism of native and of lactosylated human low density lipoprotein: evidence for two pathways for catabolism of exogenous proteins in rat hepatocytes. Proceedings of the National Academy of Sciences of the United States of America. 77: 5923-7. PMID 6160586 DOI: 10.1073/Pnas.77.10.5923  0.479
1979 Pittman RC, Attie AD, Carew TE, Steinberg D. Tissue sites of degradation of low density lipoprotein: application of a method for determining the fate of plasma proteins. Proceedings of the National Academy of Sciences of the United States of America. 76: 5345-9. PMID 228286 DOI: 10.1073/Pnas.76.10.5345  0.457
1979 Attie AD, Weinstein DB, Freeze HH, Pittman RC, Steinberg D. Unaltered catabolism of desialylated low-density lipoprotein in the pig and in cultured rat hepatocytes. The Biochemical Journal. 180: 647-54. PMID 90503 DOI: 10.1042/Bj1800647  0.383
1979 Pittman RC, Green SR, Attie AD, Steinberg D. Radiolabeled sucrose covalently linked to protein. A device for quantifying degradation of plasma proteins catabolized by lysosomal mechanisms. The Journal of Biological Chemistry. 254: 6876-9. PMID 88445  0.396
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