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Christian W. Freudiger, Ph.D. - Publications

Affiliations: 
2011 Harvard University, Cambridge, MA, United States 
Area:
Physical Chemistry, Optics Physics
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41 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Jiang C, Chowdury A, Hou X, Kondepudi A, Freudiger CW, Conway K, Camelo-Piragua S, Orringer DA, Lee H, Hollon TC. OpenSRH: optimizing brain tumor surgery using intraoperative stimulated Raman histology. Advances in Neural Information Processing Systems. 35: 28502-28516. PMID 37082565  0.327
2022 Wadiura LI, Kiesel B, Roetzer-Pejrimovsky T, Mischkulnig M, Vogel CC, Hainfellner JA, Matula C, Freudiger CW, Orringer DA, Wöhrer A, Roessler K, Widhalm G. Toward digital histopathological assessment in surgery for central nervous system tumors using stimulated Raman histology. Neurosurgical Focus. 53: E12. PMID 36455278 DOI: 10.3171/2022.9.FOCUS22429  0.431
2022 Reinecke D, von Spreckelsen N, Mawrin C, Ion-Margineanu A, Fürtjes G, Jünger ST, Khalid F, Freudiger CW, Timmer M, Ruge MI, Goldbrunner R, Neuschmelting V. Novel rapid intraoperative qualitative tumor detection by a residual convolutional neural network using label-free stimulated Raman scattering microscopy. Acta Neuropathologica Communications. 10: 109. PMID 35933416 DOI: 10.1186/s40478-022-01411-x  0.397
2020 Hollon TC, Pandian B, Urias E, Save AV, Adapa AR, Srinivasan S, Jairath NK, Farooq Z, Marie T, Al-Holou WN, Eddy K, Heth JA, Khalsa SSS, Conway K, Sagher O, ... ... Freudiger CW, et al. Rapid, label-free detection of diffuse glioma recurrence using intraoperative stimulated Raman histology and deep neural networks. Neuro-Oncology. PMID 32672793 DOI: 10.1093/Neuonc/Noaa162  0.379
2020 Hollon TC, Pandian B, Adapa AR, Urias E, Save AV, Khalsa SSS, Eichberg DG, D'Amico RS, Farooq ZU, Lewis S, Petridis PD, Marie T, Shah AH, Garton HJL, Maher CO, ... ... Freudiger CW, et al. Near real-time intraoperative brain tumor diagnosis using stimulated Raman histology and deep neural networks. Nature Medicine. PMID 31907460 DOI: 10.1038/S41591-019-0715-9  0.484
2019 Hollon T, Urias E, Adapa A, Jairath N, Save A, Canoll PD, Lee H, Freudiger C, Orringer D. NIMG-69. RAPID INTRAOPERATIVE DIAGNOSIS OF GLIOMA RECURRENCE USING STIMULATED RAMAN HISTOLOGY AND DEEP NEURAL NETWORKS Neuro-Oncology. 21: vi177-vi177. DOI: 10.1093/Neuonc/Noz175.738  0.406
2019 Save A, Hollon T, Farooq Z, Boyett D, Hawkins-Daarud A, Yoon H, Singleton K, Clark-Swanson K, Li J, Swanson K, Freudiger C, Orringer D, Lassman A, Sims P, Grinband J, et al. TMOD-14. RADIOGRAPHIC, STIMULATED RAMAN HISTOLOGIC, AND MULTIPLEXED RNA-SEQUENCING ANALYSIS OF POST-TREATMENT RECURRENT HIGH-GRADE GLIOMAS Neuro-Oncology. 21: vi265-vi265. DOI: 10.1093/Neuonc/Noz175.1113  0.566
2018 Ji M, Arbel M, Zhang L, Freudiger CW, Hou SS, Lin D, Yang X, Bacskai BJ, Xie XS. Label-free imaging of amyloid plaques in Alzheimer's disease with stimulated Raman scattering microscopy. Science Advances. 4: eaat7715. PMID 30456301 DOI: 10.1126/Sciadv.Aat7715  0.623
2017 Orringer DA, Pandian B, Niknafs YS, Hollon TC, Boyle J, Lewis S, Garrard M, Hervey-Jumper SL, Garton HJL, Maher CO, Heth JA, Sagher O, Wilkinson DA, Snuderl M, Venneti S, ... ... Freudiger CW, et al. Rapid intraoperative histology of unprocessed surgical specimens via fibre-laser-based stimulated Raman scattering microscopy. Nature Biomedical Engineering. 1. PMID 28955599 DOI: 10.1038/S41551-016-0027  0.639
2016 Hollon T, Lewis S, Freudiger CW, Sunney Xie X, Orringer DA. Improving the accuracy of brain tumor surgery via Raman-based technology. Neurosurgical Focus. 40: E9. PMID 26926067 DOI: 10.3171/2015.12.Focus15557  0.426
2016 Orringer DA, Pandian B, Hollon TC, Niknafs YS, Boyle J, Lewis S, Hervey-Jumper SL, Garton HJ, Maher CO, Heth JA, Sagher O, Snuderl M, Venneti S, Ramkissoon S, McFadden KA, ... ... Freudiger CW, et al. SURG-13. STIMULATED RAMAN SCATTERING MICROSCOPY PROVIDES DIAGNOSTIC INTRAOPERATIVE HISTOPATHOLOGIC IMAGES IN BRAIN TUMOR PATIENTS Neuro-Oncology. 18: vi193-vi193. DOI: 10.1093/Neuonc/Now212.814  0.653
2015 Ji M, Lewis S, Camelo-Piragua S, Ramkissoon SH, Snuderl M, Venneti S, Fisher-Hubbard A, Garrard M, Fu D, Wang AC, Heth JA, Maher CO, Sanai N, Johnson TD, Freudiger CW, et al. Detection of human brain tumor infiltration with quantitative stimulated Raman scattering microscopy. Science Translational Medicine. 7: 309ra163. PMID 26468325 DOI: 10.1126/Scitranslmed.Aab0195  0.62
2015 Lu FK, Basu S, Igras V, Hoang MP, Ji M, Fu D, Holtom GR, Neel VA, Freudiger CW, Fisher DE, Xie XS. Label-free DNA imaging in vivo with stimulated Raman scattering microscopy. Proceedings of the National Academy of Sciences of the United States of America. PMID 26324899 DOI: 10.1073/Pnas.1515121112  0.781
2014 Freudiger CW, Yang W, Holtom GR, Peyghambarian N, Xie XS, Kieu KQ. Stimulated Raman Scattering Microscopy with a Robust Fibre Laser Source. Nature Photonics. 8: 153-159. PMID 25313312 DOI: 10.1038/Nphoton.2013.360  0.694
2014 Saar BG, Freudiger CW, Xu X, Huttner A, Kesari S, Young G, Xie XS. Coherent Raman tissue imaging in the brain. Cold Spring Harbor Protocols. 2014. PMID 24786507 DOI: 10.1101/pdb.top081695  0.833
2013 Ji M, Orringer DA, Freudiger CW, Ramkissoon S, Liu X, Lau D, Golby AJ, Norton I, Hayashi M, Agar NY, Young GS, Spino C, Santagata S, Camelo-Piragua S, Ligon KL, et al. Rapid, label-free detection of brain tumors with stimulated Raman scattering microscopy. Science Translational Medicine. 5: 201ra119. PMID 24005159 DOI: 10.1126/Scitranslmed.3005954  0.535
2013 Kong L, Ji M, Holtom GR, Fu D, Freudiger CW, Xie XS. Multicolor stimulated Raman scattering microscopy with a rapidly tunable optical parametric oscillator. Optics Letters. 38: 145-7. PMID 23454943 DOI: 10.1364/Ol.38.000145  0.76
2013 Fu D, Holtom G, Freudiger C, Zhang X, Xie XS. Hyperspectral imaging with stimulated Raman scattering by chirped femtosecond lasers. The Journal of Physical Chemistry. B. 117: 4634-40. PMID 23256635 DOI: 10.1021/Jp308938T  0.8
2012 Lu FK, Ji M, Fu D, Ni X, Freudiger CW, Holtom G, Xie XS. Multicolor stimulated Raman scattering (SRS) microscopy. Molecular Physics. 110: 1927-1932. PMID 23504195 DOI: 10.1080/00268976.2012.695028  0.747
2012 Freudiger CW, Pfannl R, Orringer DA, Saar BG, Ji M, Zeng Q, Ottoboni L, Wei Y, Ying W, Waeber C, Sims JR, De Jager PL, Sagher O, Philbert MA, Xu X, et al. Multicolored stain-free histopathology with coherent Raman imaging. Laboratory Investigation; a Journal of Technical Methods and Pathology. 92: 1492-502. PMID 22906986 DOI: 10.1038/Labinvest.2012.109  0.795
2012 Zhang X, Roeffaers MB, Basu S, Daniele JR, Fu D, Freudiger CW, Holtom GR, Xie XS. Label-free live-cell imaging of nucleic acids using stimulated Raman scattering microscopy. Chemphyschem : a European Journal of Chemical Physics and Physical Chemistry. 13: 1054-9. PMID 22368112 DOI: 10.1002/Cphc.201100890  0.846
2012 Fu D, Lu FK, Zhang X, Freudiger C, Pernik DR, Holtom G, Xie XS. Quantitative chemical imaging with multiplex stimulated Raman scattering microscopy. Journal of the American Chemical Society. 134: 3623-6. PMID 22316340 DOI: 10.1021/Ja210081H  0.801
2012 Freudiger CW, Pfannl R, Orringer DA, Saar BG, Ji M, Zeng Q, Ottoboni L, Ying W, Waeber C, Sims JR, De Jager PL, Sagher O, Philbert MA, Xu X, Kesari S, et al. Erratum: Multicolored stain-free histopathology with coherent Raman imaging Laboratory Investigation. 92: 1661-1661. DOI: 10.1038/Labinvest.2012.139  0.783
2011 Freudiger CW, Min W, Holtom GR, Xu B, Dantus M, Xie XS. Highly specific label-free molecular imaging with spectrally tailored excitation stimulated Raman scattering (STE-SRS) microscopy. Nature Photonics. 5: 103-109. PMID 23015809 DOI: 10.1038/Nphoton.2010.294  0.781
2011 Saar BG, Johnston RS, Freudiger CW, Xie XS, Seibel EJ. Coherent Raman scanning fiber endoscopy. Optics Letters. 36: 2396-8. PMID 21725423 DOI: 10.1364/Ol.36.002396  0.838
2011 Freudiger CW, Roeffaers MB, Zhang X, Saar BG, Min W, Xie XS. Optical heterodyne-detected Raman-induced Kerr effect (OHD-RIKE) microscopy. The Journal of Physical Chemistry. B. 115: 5574-81. PMID 21504149 DOI: 10.1021/Jp1113834  0.834
2011 Roeffaers MB, Zhang X, Freudiger CW, Saar BG, van Ruijven M, van Dalen G, Xiao C, Xie XS. Label-free imaging of biomolecules in food products using stimulated Raman microscopy. Journal of Biomedical Optics. 16: 021118. PMID 21473164 DOI: 10.1117/1.3516591  0.843
2011 Min W, Freudiger CW, Lu S, Xie XS. Coherent nonlinear optical imaging: beyond fluorescence microscopy. Annual Review of Physical Chemistry. 62: 507-30. PMID 21453061 DOI: 10.1146/Annurev.Physchem.012809.103512  0.783
2011 Wang MC, Min W, Freudiger CW, Ruvkun G, Xie XS. RNAi screening for fat regulatory genes with SRS microscopy. Nature Methods. 8: 135-8. PMID 21240281 DOI: 10.1038/Nmeth.1556  0.667
2011 Freudiger C, Xie X. In vivo Imaging with Stimulated Raman Scattering Microscopy Optics and Photonics News. 22: 27. DOI: 10.1364/OPN.22.12.000027  0.572
2011 Wang K, Freudiger CW, Lee JH, Saar BG, Xie XS, Xu C. All fiber, 1064-nm time-lens source for coherent anti-Stokes Raman scattering and stimulated Raman scattering microscopy Progress in Biomedical Optics and Imaging - Proceedings of Spie. 7903. DOI: 10.1117/12.875898  0.8
2010 Roeffaers MB, Zhang X, Freudiger CW, Saar BG, van Ruijven M, van Dalen G, Xiao C, Xie XS. Label-free imaging of biomolecules in food products using stimulated Raman microscopy. Journal of Biomedical Optics. 15: 066016. PMID 21198190 DOI: 10.1117/1.3516591  0.842
2010 Wang K, Freudiger CW, Lee JH, Saar BG, Xie XS, Xu C. Synchronized time-lens source for coherent Raman scattering microscopy. Optics Express. 18: 24019-24. PMID 21164749 DOI: 10.1364/Oe.18.024019  0.791
2010 Saar BG, Freudiger CW, Reichman J, Stanley CM, Holtom GR, Xie XS. Video-rate molecular imaging in vivo with stimulated Raman scattering. Science (New York, N.Y.). 330: 1368-70. PMID 21127249 DOI: 10.1126/Science.1197236  0.838
2010 Saar BG, Zeng Y, Freudiger CW, Liu YS, Himmel ME, Xie XS, Ding SY. Label-free, real-time monitoring of biomass processing with stimulated Raman scattering microscopy. Angewandte Chemie (International Ed. in English). 49: 5476-9. PMID 20589818 DOI: 10.1002/Anie.201000900  0.792
2009 Saar BG, Holtom GR, Freudiger CW, Ackermann C, Hill W, Xie XS. Intracavity wavelength modulation of an optical parametric oscillator for coherent Raman microscopy. Optics Express. 17: 12532-9. PMID 19654655 DOI: 10.1364/Oe.17.012532  0.807
2009 Freudiger CW, Min W, Saar BG, Xie XS. Stimulated Raman scattering microscopy for label-free chemical imaging Optics and Photonics News. 20: 30. DOI: 10.1364/Opn.20.12.000030  0.84
2009 Min W, Freudiger CW, Lu S, He C, Kang JX, Xie S. Stimulated raman scattering microscopy for biomedical imaging Progress in Biomedical Optics and Imaging - Proceedings of Spie. 7183. DOI: 10.1117/12.809802  0.779
2008 Freudiger CW, Min W, Saar BG, Lu S, Holtom GR, He C, Tsai JC, Kang JX, Xie XS. Label-free biomedical imaging with high sensitivity by stimulated Raman scattering microscopy. Science (New York, N.Y.). 322: 1857-61. PMID 19095943 DOI: 10.1126/Science.1165758  0.846
2008 Girkin JM, Poland SP, Wright AJ, Freudiger C, Evans CL, Xie XS. Adaptive optics applied to coherent anti-Stokes Raman scattering microscopy Progress in Biomedical Optics and Imaging - Proceedings of Spie. 6860. DOI: 10.1117/12.764445  0.735
2007 Wright AJ, Poland SP, Girkin JM, Freudiger CW, Evans CL, Xie XS. Adaptive optics for enhanced signal in CARS microscopy. Optics Express. 15: 18209-19. PMID 19551119 DOI: 10.1364/Oe.15.018209  0.718
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