Sophia Y. Breusegem, Ph.D. - Publications
Affiliations: | 2002 | University of Illinois, Urbana-Champaign, Urbana-Champaign, IL |
Area:
General Biophysics, Animal Physiology BiologyYear | Citation | Score | |||
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2002 | Breusegem SY, Clegg RM, Loontiens FG. Base-sequence specificity of Hoechst 33258 and DAPI binding to five (A/T)4 DNA sites with kinetic evidence for more than one high-affinity Hoechst 33258-AATT complex. Journal of Molecular Biology. 315: 1049-61. PMID 11827475 DOI: 10.1006/Jmbi.2001.5301 | 0.626 | |||
2001 | Breusegem SY, Loontiens FG, Regenfuss P, Clegg RM. Kinetics of binding of Hoechst dyes to DNA studied by stopped-flow fluorescence techniques. Methods in Enzymology. 340: 212-33. PMID 11494850 DOI: 10.1016/S0076-6879(01)40424-1 | 0.579 | |||
2001 | Breusegem SY, Sadat-Ebrahimi SE, Douglas KT, Bichenkova EV, Clegg RM, Loontiens FG. Experimental precedent for the need to involve the primary hydration layer of DNA in lead drug design. Journal of Medicinal Chemistry. 44: 2503-6. PMID 11472203 DOI: 10.1021/Jm0100943 | 0.621 | |||
2001 | Breusegem SY, Sadat-Ebrahimi SE, Douglas KT, Clegg RM, Loontiens FG. Increased stability and lifetime of the complex formed between DNA and meta-phenyl-substituted Hoechst dyes as studied by fluorescence titrations and stopped-flow kinetics. Journal of Molecular Biology. 308: 649-63. PMID 11350167 DOI: 10.1006/Jmbi.2001.4615 | 0.613 | |||
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