| Year |
Citation |
Score |
| 2022 |
Lou MF. Glutathione and Glutaredoxin in Redox Regulation and Cell Signaling of the Lens. Antioxidants (Basel, Switzerland). 11. PMID 36290696 DOI: 10.3390/antiox11101973 |
0.364 |
|
| 2019 |
Daszynski DM, Santhoshkumar P, Phadte AS, Sharma KK, Zhong HA, Lou MF, Kador PF. Failure of Oxysterols Such as Lanosterol to Restore Lens Clarity from Cataracts. Scientific Reports. 9: 8459. PMID 31186457 DOI: 10.1038/S41598-019-44676-4 |
0.365 |
|
| 2017 |
Zhang J, Yan H, Lou MF. Does oxidative stress play any role in diabetic cataract formation? ----Re-evaluation using a thioltransferase gene knockout mouse model. Experimental Eye Research. PMID 28579033 DOI: 10.1016/J.Exer.2017.05.014 |
0.41 |
|
| 2015 |
Wei M, Xing KY, Fan YC, Libondi T, Lou MF. Loss of thiol repair systems in human cataractous lenses. Investigative Ophthalmology & Visual Science. 56: 598-605. PMID 25537203 DOI: 10.1167/Iovs.14-15452 |
0.347 |
|
| 2015 |
Upadhyaya B, Tian X, Wu H, Lou MF. Expression and distribution of thiol-regulating enzyme glutaredoxin 2 (GRX2) in porcine ocular tissues. Experimental Eye Research. 130: 58-65. PMID 25479045 DOI: 10.1016/J.Exer.2014.12.004 |
0.377 |
|
| 2014 |
Wu H, Yu Y, David L, Ho YS, Lou MF. Glutaredoxin 2 (Grx2) gene deletion induces early onset of age-dependent cataracts in mice. The Journal of Biological Chemistry. 289: 36125-39. PMID 25362663 DOI: 10.1074/Jbc.M114.620047 |
0.335 |
|
| 2013 |
Mailloux RJ, Xuan JY, Beauchamp B, Jui L, Lou M, Harper ME. Glutaredoxin-2 is required to control proton leak through uncoupling protein-3. The Journal of Biological Chemistry. 288: 8365-79. PMID 23335511 DOI: 10.1074/Jbc.M112.442905 |
0.364 |
|
| 2013 |
Yu Y, Xing K, Badamas R, Kuszynski CA, Wu H, Lou MF. Overexpression of thioredoxin-binding protein 2 increases oxidation sensitivity and apoptosis in human lens epithelial cells. Free Radical Biology & Medicine. 57: 92-104. PMID 23291592 DOI: 10.1016/J.Freeradbiomed.2012.12.022 |
0.436 |
|
| 2012 |
Zhang P, Xing K, Randazzo J, Blessing K, Lou MF, Kador PF. Osmotic stress, not aldose reductase activity, directly induces growth factors and MAPK signaling changes during sugar cataract formation. Experimental Eye Research. 101: 36-43. PMID 22710095 DOI: 10.1016/J.Exer.2012.05.007 |
0.356 |
|
| 2011 |
Wu H, Lin L, Giblin F, Ho YS, Lou MF. Glutaredoxin 2 knockout increases sensitivity to oxidative stress in mouse lens epithelial cells. Free Radical Biology & Medicine. 51: 2108-17. PMID 21983434 DOI: 10.1016/J.Freeradbiomed.2011.09.011 |
0.404 |
|
| 2011 |
Wang Y, Xing KY, Lou MF. Regulation of cytosolic phospholipase A2 (cPLA2alpha) and its association with cell proliferation in human lens epithelial cells. Investigative Ophthalmology & Visual Science. 52: 8231-40. PMID 21896865 DOI: 10.1167/Iovs.11-7542 |
0.315 |
|
| 2011 |
Kasaikina MV, Fomenko DE, Labunskyy VM, Lachke SA, Qiu W, Moncaster JA, Zhang J, Wojnarowicz MW, Natarajan SK, Malinouski M, Schweizer U, Tsuji PA, Carlson BA, Maas RL, Lou MF, et al. Roles of the 15-kDa selenoprotein (Sep15) in redox homeostasis and cataract development revealed by the analysis of Sep 15 knockout mice. The Journal of Biological Chemistry. 286: 33203-12. PMID 21768092 DOI: 10.1074/Jbc.M111.259218 |
0.36 |
|
| 2011 |
Pan Q, Qiu WY, Huo YN, Yao YF, Lou MF. Low levels of hydrogen peroxide stimulate corneal epithelial cell adhesion, migration, and wound healing. Investigative Ophthalmology & Visual Science. 52: 1723-34. PMID 21087961 DOI: 10.1167/Iovs.10-5866 |
0.336 |
|
| 2010 |
Xing KY, Lou MF. Effect of age on the thioltransferase (glutaredoxin) and thioredoxin systems in the human lens. Investigative Ophthalmology & Visual Science. 51: 6598-604. PMID 20610843 DOI: 10.1167/Iovs.10-5672 |
0.329 |
|
| 2010 |
Wu H, Xing K, Lou MF. Glutaredoxin 2 prevents H(2)O(2)-induced cell apoptosis by protecting complex I activity in the mitochondria. Biochimica Et Biophysica Acta. 1797: 1705-15. PMID 20547138 DOI: 10.1016/J.Bbabio.2010.06.003 |
0.347 |
|
| 2009 |
Meyer LM, Löfgren S, Ho YS, Lou M, Wegener A, Holz F, Söderberg P. Absence of glutaredoxin1 increases lens susceptibility to oxidative stress induced by UVR-B. Experimental Eye Research. 89: 833-9. PMID 19664619 DOI: 10.1016/J.Exer.2009.07.020 |
0.353 |
|
| 2009 |
Huo Y, Qiu WY, Pan Q, Yao YF, Xing K, Lou MF. Reactive oxygen species (ROS) are essential mediators in epidermal growth factor (EGF)-stimulated corneal epithelial cell proliferation, adhesion, migration, and wound healing. Experimental Eye Research. 89: 876-86. PMID 19635476 DOI: 10.1016/J.Exer.2009.07.012 |
0.39 |
|
| 2009 |
Wang Y, Lou MF. The regulation of NADPH oxidase and its association with cell proliferation in human lens epithelial cells. Investigative Ophthalmology & Visual Science. 50: 2291-300. PMID 19136702 DOI: 10.1167/Iovs.08-2568 |
0.382 |
|
| 2009 |
LOU M, LECHNER J, XING K, KADOR P. Loss of thioredoxin activity as an important contributor to oxidative stress in lens of diabetic rats Acta Ophthalmologica. 87: 0-0. DOI: 10.1111/J.1755-3768.2009.3141.X |
0.372 |
|
| 2008 |
Löfgren S, Fernando MR, Xing KY, Wang Y, Kuszynski CA, Ho YS, Lou MF. Effect of thioltransferase (glutaredoxin) deletion on cellular sensitivity to oxidative stress and cell proliferation in lens epithelial cells of thioltransferase knockout mouse. Investigative Ophthalmology & Visual Science. 49: 4497-505. PMID 18586881 DOI: 10.1167/Iovs.07-1404 |
0.418 |
|
| 2007 |
Liyanage NP, Fernando MR, Lou MF. Regulation of the bioavailability of thioredoxin in the lens by a specific thioredoxin-binding protein (TBP-2). Experimental Eye Research. 85: 270-9. PMID 17603038 DOI: 10.1016/J.Exer.2007.05.001 |
0.442 |
|
| 2007 |
Yan H, Harding JJ, Xing K, Lou MF. Revival of glutathione reductase in human cataractous and clear lens extracts by thioredoxin and thioredoxin reductase, in conjunction with alpha-crystallin or thioltransferase. Current Eye Research. 32: 455-63. PMID 17514531 DOI: 10.1080/02713680701257837 |
0.37 |
|
| 2007 |
Xing K, Raza A, Löfgren S, Fernando MR, Ho YS, Lou MF. Low molecular weight protein tyrosine phosphatase (LMW-PTP) and its possible physiological functions of redox signaling in the eye lens. Biochimica Et Biophysica Acta. 1774: 545-55. PMID 17428749 DOI: 10.1016/J.Bbapap.2007.03.001 |
0.425 |
|
| 2007 |
Chen KC, Zhou Y, Zhang W, Lou MF. Control of PDGF-induced reactive oxygen species (ROS) generation and signal transduction in human lens epithelial cells. Molecular Vision. 13: 374-87. PMID 17392688 |
0.509 |
|
| 2006 |
Fernando MR, Lechner JM, Löfgren S, Gladyshev VN, Lou MF. Mitochondrial thioltransferase (glutaredoxin 2) has GSH-dependent and thioredoxin reductase-dependent peroxidase activities in vitro and in lens epithelial cells. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 20: 2645-7. PMID 17065220 DOI: 10.1096/Fj.06-5919Fje |
0.435 |
|
| 2006 |
Persa C, Osmotherly K, Chao-Wei Chen K, Moon S, Lou MF. The distribution of cystathionine beta-synthase (CBS) in the eye: implication of the presence of a trans-sulfuration pathway for oxidative stress defense. Experimental Eye Research. 83: 817-23. PMID 16769053 DOI: 10.1016/J.Exer.2006.04.001 |
0.328 |
|
| 2006 |
Yegorova S, Yegorov O, Lou MF. Thioredoxin induced antioxidant gene expressions in human lens epithelial cells. Experimental Eye Research. 83: 783-92. PMID 16712839 DOI: 10.1016/J.Exer.2006.03.018 |
0.44 |
|
| 2005 |
Rachdan D, Lou MF, Harding JJ. Glutathione reductase from human cataract lenses can be revived by reducing agents and by a molecular chaperone, alpha-crystallin. Current Eye Research. 30: 919-25. PMID 16251130 DOI: 10.1080/02713680590953110 |
0.331 |
|
| 2005 |
Moon S, Fernando MR, Lou MF. Induction of thioltransferase and thioredoxin/thioredoxin reductase systems in cultured porcine lenses under oxidative stress. Investigative Ophthalmology & Visual Science. 46: 3783-9. PMID 16186363 DOI: 10.1167/Iovs.05-0237 |
0.359 |
|
| 2004 |
Persa C, Pierce A, Ma Z, Kabil O, Lou MF. The presence of a transsulfuration pathway in the lens: a new oxidative stress defense system. Experimental Eye Research. 79: 875-86. PMID 15642325 DOI: 10.1016/J.Exer.2004.06.029 |
0.473 |
|
| 2004 |
Rachdan D, Lou MF, Harding JJ. Revival of inactive glyceraldehyde 3-phosphate dehydrogenase in human cataract lenses by reduction. Experimental Eye Research. 79: 105-9. PMID 15183105 DOI: 10.1016/J.Exer.2004.02.013 |
0.355 |
|
| 2004 |
Chen KC, Zhou Y, Xing K, Krysan K, Lou MF. Platelet derived growth factor (PDGF)-induced reactive oxygen species in the lens epithelial cells: the redox signaling. Experimental Eye Research. 78: 1057-67. PMID 15109912 DOI: 10.1016/J.Exer.2004.02.004 |
0.565 |
|
| 2004 |
Fernando MR, Satake M, Monnier VM, Lou MF. Thioltranferase mediated ascorbate recycling in human lens epithelial cells. Investigative Ophthalmology & Visual Science. 45: 230-7. PMID 14691178 DOI: 10.1167/Iovs.03-0545 |
0.391 |
|
| 2003 |
Xing K, Lou MF. The possible physiological function of thioltransferase in cells. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 17: 2088-90. PMID 12958160 DOI: 10.1096/Fj.02-1164Fje |
0.452 |
|
| 2003 |
Lou MF. Redox regulation in the lens. Progress in Retinal and Eye Research. 22: 657-82. PMID 12892645 DOI: 10.1016/S1350-9462(03)00050-8 |
0.437 |
|
| 2003 |
Yegorova S, Liu A, Lou MF. Human lens thioredoxin: molecular cloning and functional characterization. Investigative Ophthalmology & Visual Science. 44: 3263-71. PMID 12882768 DOI: 10.1167/Iovs.02-1322 |
0.412 |
|
| 2003 |
Zatechka DS, Kador PF, Garcia-Castiñeiras S, Lou MF. Diabetes can alter the signal transduction pathways in the lens of rats. Diabetes. 52: 1014-22. PMID 12663474 DOI: 10.2337/Diabetes.52.4.1014 |
0.337 |
|
| 2002 |
Giblin FJ, Leverenz VR, Padgaonkar VA, Unakar NJ, Dang L, Lin LR, Lou MF, Reddy VN, Borchman D, Dillon JP. UVA light in vivo reaches the nucleus of the guinea pig lens and produces deleterious, oxidative effects. Experimental Eye Research. 75: 445-58. PMID 12387792 DOI: 10.1006/Exer.2002.2039 |
0.362 |
|
| 2002 |
Steven Zatechka D, Lou MF. Studies of the mitogen-activated protein kinases and phosphatidylinositol-3 kinase in the lens. 2. The intercommunications. Experimental Eye Research. 75: 177-92. PMID 12137763 DOI: 10.1006/Exer.2002.2018 |
0.3 |
|
| 2002 |
Zatechka SD, Lou MF. Studies of the mitogen-activated protein kinases and phosphatidylinositol-3 kinase in the lens. 1. The mitogenic and stress responses. Experimental Eye Research. 74: 703-17. PMID 12126944 DOI: 10.1006/Exer.2002.1168 |
0.349 |
|
| 2002 |
Xing KY, Lou MF. Effect of H2O2 on human lens epithelial cells and the possible mechanism for oxidative damage repair by thioltransferase Experimental Eye Research. 74: 113-122. PMID 11878824 DOI: 10.1006/Exer.2001.1103 |
0.445 |
|
| 2002 |
Xu Z, Patel KP, Lou MF, Rozanski GJ. Up-regulation of K(+) channels in diabetic rat ventricular myocytes by insulin and glutathione. Cardiovascular Research. 53: 80-8. PMID 11744015 DOI: 10.1016/S0008-6363(01)00446-1 |
0.304 |
|
| 2001 |
Gladyshev VN, Liu A, Novoselov SV, Krysan K, Sun QA, Kryukov VM, Kryukov GV, Lou MF. Identification and characterization of a new mammalian glutaredoxin (thioltransferase), Grx2. The Journal of Biological Chemistry. 276: 30374-80. PMID 11397793 DOI: 10.1074/Jbc.M100020200 |
0.397 |
|
| 2001 |
Raghavachari N, Krysan K, Xing K, Lou MF. Regulation of thioltransferase expression in human lens epithelial cells Investigative Ophthalmology and Visual Science. 42: 1002-1008. PMID 11274078 |
0.352 |
|
| 2001 |
Qiao F, Xing K, Liu A, Ehlers N, Raghavachari N, Lou MF. Human lens thioltransferase: Cloning, purification, and function Investigative Ophthalmology and Visual Science. 42: 743-751. PMID 11222536 |
0.322 |
|
| 2000 |
Qiao F, Xing K, Lou MF. Modulation of lens glycolytic pathway by thioltransferase Experimental Eye Research. 70: 745-753. PMID 10843779 DOI: 10.1006/Exer.2000.0836 |
0.403 |
|
| 2000 |
Kador PF, Lee JW, Fujisawa S, Blessing K, Lou MF. Relative importance of aldose reductase versus nonenzymatic glycosylation on sugar cataract formation in diabetic rats Journal of Ocular Pharmacology and Therapeutics. 16: 149-160. PMID 10803425 DOI: 10.1089/Jop.2000.16.149 |
0.304 |
|
| 2000 |
Lou MF. Thiol regulation in the lens Journal of Ocular Pharmacology and Therapeutics. 16: 137-148. PMID 10803424 DOI: 10.1089/Jop.2000.16.137 |
0.453 |
|
| 1999 |
Raghavachari N, Qiao F, Shinohara T, Kikuchi T, Lou MF. Cloning, high level-expression and characterization of human lens thioltransferase Experimental Eye Research. 69: 583. PMID 10712076 DOI: 10.1006/Exer.1997.0449 |
0.314 |
|
| 1999 |
Raghavachari N, Qiao F, Lou MF. Does glutathione-S-transferase dethiolate lens protein-thiol mixed disulfides? - A comparative study with thioltransferase Experimental Eye Research. 68: 715-724. PMID 10375435 DOI: 10.1006/Exer.1999.0659 |
0.427 |
|
| 1999 |
Lou MF, Dickerson JE, Tung WH, Wolfe JK, Chylack LT. Correlation of nuclear color and opalescence with protein S-thiolation in human lenses. Experimental Eye Research. 68: 547-52. PMID 10328968 DOI: 10.1006/Exer.1998.0638 |
0.357 |
|
| 1999 |
Hanson SRA, Chen AA, Smith JB, Lou MF. Thiolation of the γB-crystallins in intact bovine lens exposed to hydrogen peroxide Journal of Biological Chemistry. 274: 4735-4742. PMID 9988710 DOI: 10.1074/Jbc.274.8.4735 |
0.35 |
|
| 1998 |
Dickerson JE, Hellberg M, Lou MF. Evaluation of AL-05712 and AL-05741 as thioltransferase mimics for the prevention and recovery of pre-cataractous changes in lens Journal of Ocular Pharmacology and Therapeutics. 14: 437-445. PMID 9811233 DOI: 10.1089/Jop.1998.14.437 |
0.327 |
|
| 1998 |
Lou MF, Wang GM, Wu F, Raghavachari N, Reddan JR. Thioltransferase is present in the lens epithelial cells as a highly oxidative stress-resistant enzyme Experimental Eye Research. 66: 477-485. PMID 9593640 DOI: 10.1006/Exer.1997.0464 |
0.471 |
|
| 1997 |
Dickerson JE, Lou MF. Free cysteine levels in normal human lenses Experimental Eye Research. 65: 451-454. PMID 9299182 DOI: 10.1006/Exer.1997.0343 |
0.308 |
|
| 1997 |
Wang GM, Raghavachari N, Lou MF. Relationship of protein-glutathione mixed disulfide and thioltransferase in H2O2-induced cataract in cultured pig lens Experimental Eye Research. 64: 693-700. PMID 9245898 DOI: 10.1006/Exer.1996.0251 |
0.408 |
|
| 1996 |
Raghavachari N, Lou MF. Evidence for the presence of thioltransferase in the lens Experimental Eye Research. 63: 433-441. PMID 8944550 DOI: 10.1006/Exer.1996.0133 |
0.409 |
|
| 1996 |
Wang GM, Reddan J, Wu F, Lou MF. Thioltransferase as a highly oxidative stress-resistant enzyme in the cultured lens epithelial cells Investigative Ophthalmology and Visual Science. 37. |
0.328 |
|
| 1995 |
Lou MF, Xu GT, Cui XL. Further studies on the dynamic changes of glutathione and protein-thiol mixed disulfides in h2o2 induced cataract in rat lenses: Distributions and effect of aging Current Eye Research. 14: 951-958. PMID 8549161 DOI: 10.3109/02713689508995135 |
0.398 |
|
| 1995 |
Dickerson JE, Lou MF, Gracy RW. Ascorbic acid mediated alteration of αcrystallin secondary structure Current Eye Research. 14: 163-166. PMID 7768109 DOI: 10.3109/02713689508999929 |
0.311 |
|
| 1995 |
Dickerson JE, Lou MF, Gracy RW. The culture of rat lenses in high sugar media: Effect on mixed disulfide levels Current Eye Research. 14: 109-118. PMID 7768104 DOI: 10.3109/02713689508999922 |
0.378 |
|
| 1992 |
Lou MF, Dickerson JE. Protein-thiol mixed disulfides in human lens Experimental Eye Research. 55: 889-896. PMID 1486943 DOI: 10.1016/0014-4835(92)90015-K |
0.305 |
|
| 1992 |
Reddy VN, Lin LR, Giblin FJ, Lou M, Kador PF, Kinoshita JH. The efficacy of aldose reductase inhibitors on polyol accumulation in human lens and retinal pigment epithelium in tissue culture. Journal of Ocular Pharmacology. 8: 43-52. PMID 1402294 DOI: 10.1089/Jop.1992.8.43 |
0.327 |
|
| 1989 |
Vivekanandan S, Lou MF. Evidence for the presence of phosphoinositide cycle and its involvement in cellular signal transduction in the rabbit Lens Current Eye Research. 8: 101-111. PMID 2539949 DOI: 10.3109/02713688909013899 |
0.361 |
|
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