Ian Anthony James Lorimer - Publications

Affiliations: 
Biochemistry, Microbiology and Immunology University of Ottawa, Ottawa, ON, Canada 
Area:
Biochemistry, Cell Biology, Oncology
Website:
http://www.ohri.ca/profile/ilorimer

31 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Lorimer IA. Aberrant Rac pathway signalling in glioblastoma. Small Gtpases. 1-15. PMID 31032735 DOI: 10.1080/21541248.2019.1612694  0.322
2019 Jacques FH, Nicholas G, Lorimer I, Sikatifoko V, Prévost J. Avelumab in newly diagnosed glioblastoma multiforme: The SEJ study. Journal of Clinical Oncology. 37. DOI: 10.1200/Jco.2019.37.15_Suppl.E13571  0.314
2019 Lorimer I, Lavictoire S, Jomaa D, Gont A, Jardine K. Csig-12. Prex1 Links Aberrant Pi 3-Kinase Pathway Signaling To Maintenance Of The Neural Stem Cell-Like Phenotype Of Glioblastoma Cells Neuro-Oncology. 21. DOI: 10.1093/Neuonc/Noz175.183  0.43
2018 Kumar R, Lorimer I. Csig-06. The Molecular Subtype Of Primary Glioblastoma Cells Correlates With Response To Therapeutic Agents That Induce Apoptosis Or Senescence Neuro-Oncology. 20. DOI: 10.1093/Neuonc/Noy148.172  0.351
2016 Gont A, Daneshmand M, Woulfe J, Lavictoire SJ, Lorimer IA. PREX1 integrates G protein-coupled receptor and phosphoinositide 3-kinase signaling to promote glioblastoma invasion. Oncotarget. PMID 28051998 DOI: 10.18632/Oncotarget.14348  0.456
2015 Restall IJ, Parolin DA, Daneshmand M, Hanson JE, Simard MA, Fitzpatrick ME, Kumar R, Lavictoire SJ, Lorimer IA. PKCι DEPLETION INITIATES MITOTIC SLIPPAGE-INDUCED SENESCENCE IN GLIOBLASTOMA. Cell Cycle (Georgetown, Tex.). 0. PMID 26208522 DOI: 10.1080/15384101.2015.1071744  0.715
2015 Jahani-Asl A, Yin H, Soleimani V, Chang N, Sincennes M, Luchman HA, Sidharth P, Scott A, Lorimer I, Perkins T, Ligon K, Weiss S, Rudnicki M, Bonni A. CSIG-06EGFRvIII REQUIRES OSMR AS A CO-RECEPTOR TO DRIVE GLIOBLASTOMA PATHOGENESIS Neuro-Oncology. 17: v67.2-v67. DOI: 10.1093/Neuonc/Nov210.06  0.377
2014 Gont A, Hanson JE, Lavictoire SJ, Daneshmand M, Nicholas G, Woulfe J, Kassam A, Da Silva VF, Lorimer IA. Inhibition of glioblastoma malignancy by Lgl1. Oncotarget. 5: 11541-51. PMID 25426552 DOI: 10.18632/Oncotarget.2580  0.469
2014 Karapetis CS, Jonker D, Daneshmand M, Hanson JE, O'Callaghan CJ, Marginean C, Zalcberg JR, Simes J, Moore MJ, Tebbutt NC, Price TJ, Shapiro JD, Pavlakis N, Gibbs P, Van Hazel GA, ... ... Lorimer IA, et al. PIK3CA, BRAF, and PTEN status and benefit from cetuximab in the treatment of advanced colorectal cancer--results from NCIC CTG/AGITG CO.17. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 20: 744-53. PMID 24218517 DOI: 10.1158/1078-0432.Ccr-13-0606  0.309
2013 Goss GD, O'Callaghan C, Lorimer I, Tsao MS, Masters GA, Jett J, Edelman MJ, Lilenbaum R, Choy H, Khuri F, Pisters K, Gandara D, Kernstine K, Butts C, Noble J, et al. Gefitinib versus placebo in completely resected non-small-cell lung cancer: results of the NCIC CTG BR19 study. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 31: 3320-6. PMID 23980091 DOI: 10.1200/Jco.2013.51.1816  0.346
2013 Liwak U, Jordan LE, Von-Holt SD, Singh P, Hanson JE, Lorimer IA, Roncaroli F, Holcik M. Loss of PDCD4 contributes to enhanced chemoresistance in Glioblastoma multiforme through de-repression of Bcl-xL translation. Oncotarget. 4: 1365-72. PMID 23965755  0.304
2013 Gont A, Hanson JE, Lavictoire SJ, Parolin DA, Daneshmand M, Restall IJ, Soucie M, Nicholas G, Woulfe J, Kassam A, Da Silva VF, Lorimer IA. PTEN loss represses glioblastoma tumor initiating cell differentiation via inactivation of Lgl1. Oncotarget. 4: 1266-79. PMID 23907540 DOI: 10.18632/Oncotarget.1164  0.705
2012 Daneshmand M, Hanson JE, Nabavi M, Hilton JF, Vandermeer L, Kanji F, Dent SF, Clemons M, Lorimer IA. Detection of PIK3CA Mutations in Breast Cancer Bone Metastases. Isrn Oncology. 2012: 492578. PMID 22970388 DOI: 10.5402/2012/492578  0.31
2012 Hilton J, Weberpals J, Lorimer I, Amin S, Islam S, Pelletier L, Daneshmand M, Hanson J, Nabavi M, Parolin D, Mallick R, Verma S. BRCA1 protein levels and PIK3CA mutations as predictive biomarkers for response to neoadjuvant chemotherapy in locally advanced breast cancer: An exploratory analysis. Oncology Letters. 4: 141-145. PMID 22807977 DOI: 10.3892/Ol.2012.697  0.363
2012 Paget JA, Restall IJ, Daneshmand M, Mersereau JA, Simard MA, Parolin DA, Lavictoire SJ, Amin MS, Islam S, Lorimer IA. Repression of cancer cell senescence by PKCι. Oncogene. 31: 3584-96. PMID 22120720 DOI: 10.1038/onc.2011.524  0.72
2011 Hilton J, Weberpals J, Lorimer I, Amin S, Islam S, Daneshmand M, Hanson J, Mallick R, Kanji F, Verma S. Abstract C1: BRCA1 protein levels and PI3KA mutations as predictive biomarkers for response to neoadjuvant chemotherapy in locally advanced breast cancer: An exploratory analysis. Molecular Cancer Therapeutics. 10. DOI: 10.1158/1535-7163.Targ-11-C1  0.38
2010 Goss GD, Lorimer I, Tsao MS, O'Callaghan CJ, Ding K, Masters GA, Roberts P, Jett JR, Edelman MJ, Shepherd FA. A phase III randomized, double-blind, placebo-controlled trial of the epidermal growth factor receptor inhibitor gefitinb in completely resected stage IB-IIIA non-small cell lung cancer (NSCLC): NCIC CTG BR.19. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 28: LBA7005. PMID 27937477 DOI: 10.1200/Jco.2010.28.18_Suppl.Lba7005  0.334
2010 Baldwin RM, Barrett GM, Parolin DA, Gillies JK, Paget JA, Lavictoire SJ, Gray DA, Lorimer IA. Coordination of glioblastoma cell motility by PKCι. Molecular Cancer. 9: 233. PMID 20815904 DOI: 10.1186/1476-4598-9-233  0.378
2010 Restall IJ, Lorimer IA. Induction of premature senescence by hsp90 inhibition in small cell lung cancer. Plos One. 5: e11076. PMID 20552022 DOI: 10.1371/journal.pone.0011076  0.712
2010 Hilton JF, Weberpals JI, Lorimer I, Nabavi M, Kanji F, Hopkins S, Robertson S, Daneshmand M, Verma S. Can tumor biomarkers predict response to neoadjuvant anthracycline/taxane chemotherapy in LABC? Journal of Clinical Oncology. 28: 633-633. DOI: 10.1200/Jco.2010.28.15_Suppl.633  0.313
2010 Paget J, Daneshmand M, Amin MS, Islam S, Lorimer I. Abstract 3171: Expression of PKC iota in breast cancer Cancer Research. 70: 3171-3171. DOI: 10.1158/1538-7445.Am10-3171  0.444
2008 Cemeus C, Zhao TT, Barrett GM, Lorimer IA, Dimitroulakos J. Lovastatin enhances gefitinib activity in glioblastoma cells irrespective of EGFRvIII and PTEN status. Journal of Neuro-Oncology. 90: 9-17. PMID 18566746 DOI: 10.1007/S11060-008-9627-0  0.348
2007 Agulnik M, Cohen EW, Cohen RB, Chen EX, Vokes EE, Hotte SJ, Winquist E, Laurie S, Hayes DN, Dancey JE, Brown S, Pond GR, Lorimer I, Daneshmand M, Ho J, et al. Phase II study of lapatinib in recurrent or metastatic epidermal growth factor receptor and/or erbB2 expressing adenoid cystic carcinoma and non adenoid cystic carcinoma malignant tumors of the salivary glands. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 25: 3978-84. PMID 17761983 DOI: 10.1200/Jco.2007.11.8612  0.322
2005 Tsao MS, Sakurada A, Lorimer I, Cutz JC, Kamel-Reid S, Squire J, Ding K, Frank R, Seymour L, Shepherd F. Molecular analysis of the epidermal growth factor receptor (EGFR) gene and protein expression in patients treated with erlotinib in National Cancer Institute of Canada Clinical Trials Group (NCIC CTG) trial BR.21. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 23: 7007. PMID 27943794 DOI: 10.1200/Jco.2005.23.16_Suppl.7007  0.326
2005 Tsao MS, Sakurada A, Cutz JC, Zhu CQ, Kamel-Reid S, Squire J, Lorimer I, Zhang T, Liu N, Daneshmand M, Marrano P, da Cunha Santos G, Lagarde A, Richardson F, Seymour L, et al. Erlotinib in lung cancer - molecular and clinical predictors of outcome. The New England Journal of Medicine. 353: 133-44. PMID 16014883 DOI: 10.1056/Nejmoa050736  0.355
2005 Mackenzie MJ, Hirte HW, Glenwood G, Jean M, Goel R, Major PP, Miller WH, Panasci L, Lorimer IA, Batist G, Matthews S, Douglas L, Seymour L. A phase II trial of ZD1839 (Iressa) 750 mg per day, an oral epidermal growth factor receptor-tyrosine kinase inhibitor, in patients with metastatic colorectal cancer. Investigational New Drugs. 23: 165-70. PMID 15744593 DOI: 10.1007/S10637-005-5862-9  0.334
2002 Lorimer IA, Parolin DA, Lavictoire SJ. Induction of apoptosis in glioblastoma cells by an atypical protein kinase C pseudosubstrate peptide. Anticancer Research. 22: 623-31. PMID 12014630  0.361
1995 Lorimer IA, Wikstrand CJ, Batra SK, Bigner DD, Pastan I. Immunotoxins that target an oncogenic mutant epidermal growth factor receptor expressed in human tumors. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 1: 859-64. PMID 9816055  0.304
1994 Jain N, Brickenden A, Lorimer I, Ball EH, Sanwal BD. Interaction of procollagen I and other collagens with colligin Biochemical Journal. 304: 61-68. PMID 7998958 DOI: 10.1042/Bj3040061  0.65
1993 Clarke EP, Jain N, Brickenden A, Lorimer IA, Sanwal BD. Parallel regulation of procollagen I and colligin, a collagen-binding protein and a member of the serine protease inhibitor family. The Journal of Cell Biology. 121: 193-9. PMID 8458868 DOI: 10.1083/Jcb.121.1.193  0.565
1987 Lorimer IA, Mason ME, Sanwal BD. Levels of type I cAMP-dependent protein kinase regulatory subunit are regulated by changes in turnover rate during skeletal myogenesis Journal of Biological Chemistry. 262: 17200-17205. PMID 2445756  0.589
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