Jason Koutcher - Publications

Affiliations: 
Physiology and Biophysics Weill Cornell Medical College, New York, NY, United States 
Area:
General Biophysics, Radiology, Oncology

206 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any innacuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Bodo S, Campagne C, Thin TH, Higginson DS, Vargas HA, Hua G, Fuller JD, Ackerstaff E, Russell J, Zhang Z, Klingler S, Cho H, Kaag MG, Mazaheri Y, Rimner A, ... ... Koutcher JA, et al. Single-dose radiotherapy disables tumor cell homologous recombination via ischemia/reperfusion injury. The Journal of Clinical Investigation. PMID 30480549 DOI: 10.1172/JCI97631  0.36
2017 Han S, Stoyanova R, Lee H, Carlin SD, Koutcher JA, Cho H, Ackerstaff E. Automation of pattern recognition analysis of dynamic contrast-enhanced MRI data to characterize intratumoral vascular heterogeneity. Magnetic Resonance in Medicine. PMID 28727185 DOI: 10.1002/mrm.26822  0.36
2016 Cho H, Ackerstaff E, Carlin S, Lupu ME, Wang Y, Rizwan A, O'Donoghue J, Ling CC, Humm JL, Zanzonico PB, Koutcher JA. Corrigendum to "Noninvasive Multimodality Imaging of the Tumor Microenvironment: Registered Dynamic Magnetic Resonance Imaging and Positron Emission Tomography Studies of a Preclinical Tumor Model of Tumor Hypoxia" [Neoplasia 11 (2009) 247-259]. Neoplasia (New York, N.Y.). 18: 811. PMID 27978998 DOI: 10.1016/j.neo.2016.10.008  0.56
2014 Viola-Villegas NT, Carlin SD, Ackerstaff E, Sevak KK, Divilov V, Serganova I, Kruchevsky N, Anderson M, Blasberg RG, Andreev OA, Engelman DM, Koutcher JA, Reshetnyak YK, Lewis JS. Understanding the pharmacological properties of a metabolic PET tracer in prostate cancer. Proceedings of the National Academy of Sciences of the United States of America. 111: 7254-9. PMID 24785505 DOI: 10.1073/pnas.1405240111  0.56
2014 Bokacheva L, Ackerstaff E, LeKaye HC, Zakian K, Koutcher JA. High-field small animal magnetic resonance oncology studies. Physics in Medicine and Biology. 59: R65-R127. PMID 24374985 DOI: 10.1088/0031-9155/59/2/R65  0.56
2014 Matulewicz L, Jansen JF, Bokacheva L, Vargas HA, Akin O, Fine SW, Shukla-Dave A, Eastham JA, Hricak H, Koutcher JA, Zakian KL. Anatomic segmentation improves prostate cancer detection with artificial neural networks analysis of 1H magnetic resonance spectroscopic imaging. Journal of Magnetic Resonance Imaging : Jmri. 40: 1414-21. PMID 24243554 DOI: 10.1002/jmri.24487  0.56
2013 Arias-Mendoza F, Payne GS, Zakian K, Stubbs M, O'Connor OA, Mojahed H, Smith MR, Schwarz AJ, Shukla-Dave A, Howe F, Poptani H, Lee SC, Pettengel R, Schuster SJ, Cunningham D, ... ... Koutcher JA, et al. Noninvasive phosphorus magnetic resonance spectroscopic imaging predicts outcome to first-line chemotherapy in newly diagnosed patients with diffuse large B-cell lymphoma. Academic Radiology. 20: 1122-9. PMID 23931426 DOI: 10.1016/j.acra.2013.04.013  0.56
2013 Aytes A, Mitrofanova A, Kinkade CW, Lefebvre C, Lei M, Phelan V, LeKaye HC, Koutcher JA, Cardiff RD, Califano A, Shen MM, Abate-Shen C. ETV4 promotes metastasis in response to activation of PI3-kinase and Ras signaling in a mouse model of advanced prostate cancer. Proceedings of the National Academy of Sciences of the United States of America. 110: E3506-15. PMID 23918374 DOI: 10.1073/pnas.1303558110  0.56
2013 Rizwan A, Serganova I, Khanin R, Karabeber H, Ni X, Thakur S, Zakian KL, Blasberg R, Koutcher JA. Relationships between LDH-A, lactate, and metastases in 4T1 breast tumors. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 19: 5158-69. PMID 23833310 DOI: 10.1158/1078-0432.CCR-12-3300  0.56
2013 Xing L, Sun X, Deng X, Kotedia K, Zanzonico PB, Ackerstaff E, Koutcher JA, Ling CC, Li GC. A triple suicide gene strategy that improves therapeutic effects and incorporates multimodality molecular imaging for monitoring gene functions Cancer Gene Therapy. 20: 358-365. PMID 23722591 DOI: 10.1038/cgt.2013.28  0.56
2013 Han SH, Ackerstaff E, Stoyanova R, Carlin S, Huang W, Koutcher JA, Kim JK, Cho G, Jang G, Cho H. Gaussian mixture model-based classification of dynamic contrast enhanced MRI data for identifying diverse tumor microenvironments: preliminary results. Nmr in Biomedicine. 26: 519-32. PMID 23440683 DOI: 10.1002/nbm.2888  0.56
2013 Yoshioka T, Otero J, Chen Y, Kim YM, Koutcher JA, Satagopan J, Reuter V, Carver B, de Stanchina E, Enomoto K, Greenberg NM, Scardino PT, Scher HI, Sawyers CL, Giancotti FG. β4 Integrin signaling induces expansion of prostate tumor progenitors. The Journal of Clinical Investigation. 123: 682-99. PMID 23348745 DOI: 10.1172/JCI60720  0.56
2013 Qi J, Fong Y, Saltz L, D'Angelica MI, Kemeny NE, Gonen M, Shia J, Shukla-Dave A, Jarnagin WR, Jarnagin WM, Do RK, Schwartz LH, Koutcher JA, Zakian KL. Serial measurement of hepatic lipids during chemotherapy in patients with colorectal cancer: a 1 H MRS study. Nmr in Biomedicine. 26: 204-12. PMID 22961714 DOI: 10.1002/nbm.2837  0.56
2013 Bokacheva L, Kotedia K, Reese M, Ricketts SA, Halliday J, Le CH, Koutcher JA, Carlin S. Response of HT29 colorectal xenograft model to cediranib assessed with 18 F-fluoromisonidazole positron emission tomography, dynamic contrast-enhanced and diffusion-weighted MRI. Nmr in Biomedicine. 26: 151-63. PMID 22777834 DOI: 10.1002/nbm.2830  0.56
2013 Pu Y, Xue J, Xu B, Wang W, Gu Y, Tang R, Achilefu S, Ackerstaff E, Koutcher JA, Alfano RR. Investigation of native fluorescence spectral difference among prostate cancer cell lines with different risk levels Progress in Biomedical Optics and Imaging - Proceedings of Spie. 8577. DOI: 10.1117/12.2001443  0.56
2012 Xiong X, Chorzalska A, Dubielecka PM, White JR, Vedvyas Y, Hedvat CV, Haimovitz-Friedman A, Koutcher JA, Reimand J, Bader GD, Sawicki JA, Kotula L. Disruption of Abi1/Hssh3bp1 expression induces prostatic intraepithelial neoplasia in the conditional Abi1/Hssh3bp1 KO mice. Oncogenesis. 1: e26. PMID 23552839 DOI: 10.1038/oncsis.2012.28  0.56
2012 Stoyanova R, Huang K, Sandler K, Cho H, Carlin S, Zanzonico PB, Koutcher JA, Ackerstaff E. Mapping Tumor Hypoxia In Vivo Using Pattern Recognition of Dynamic Contrast-enhanced MRI Data. Translational Oncology. 5: 437-47. PMID 23326621 DOI: 10.1593/tlo.12319  0.56
2012 Sun X, Xing L, Deng X, Hsiao HT, Manami A, Koutcher JA, Clifton Ling C, Li GC. Hypoxia targeted bifunctional suicide gene expression enhances radiotherapy in vitro and in vivo. Radiotherapy and Oncology : Journal of the European Society For Therapeutic Radiology and Oncology. 105: 57-63. PMID 22938726 DOI: 10.1016/j.radonc.2012.07.011  0.56
2012 Lu Y, Jansen JF, Mazaheri Y, Stambuk HE, Koutcher JA, Shukla-Dave A. Extension of the intravoxel incoherent motion model to non-gaussian diffusion in head and neck cancer. Journal of Magnetic Resonance Imaging : Jmri. 36: 1088-96. PMID 22826198 DOI: 10.1002/jmri.23770  0.56
2012 Bakst RL, Lee N, He S, Chernichenko N, Chen CH, Linkov G, Le HC, Koutcher J, Vakiani E, Wong RJ. Radiation impairs perineural invasion by modulating the nerve microenvironment. Plos One. 7: e39925. PMID 22768171 DOI: 10.1371/journal.pone.0039925  0.56
2012 Han S, Paulsen JL, Zhu G, Song Y, Chun S, Cho G, Ackerstaff E, Koutcher JA, Cho H. Temporal/spatial resolution improvement of in vivo DCE-MRI with compressed sensing-optimized FLASH. Magnetic Resonance Imaging. 30: 741-52. PMID 22465192 DOI: 10.1016/j.mri.2012.02.001  0.56
2012 Rattigan YI, Patel BB, Ackerstaff E, Sukenick G, Koutcher JA, Glod JW, Banerjee D. Lactate is a mediator of metabolic cooperation between stromal carcinoma associated fibroblasts and glycolytic tumor cells in the tumor microenvironment. Experimental Cell Research. 318: 326-35. PMID 22178238 DOI: 10.1016/j.yexcr.2011.11.014  0.56
2012 Yaligar J, Thakur SB, Bokacheva L, Carlin S, Thaler HT, Rizwan A, Lupu ME, Wang Y, Matei CC, Zakian KL, Koutcher JA. Lactate MRSI and DCE MRI as surrogate markers of prostate tumor aggressiveness. Nmr in Biomedicine. 25: 113-22. PMID 21618306 DOI: 10.1002/nbm.1723  0.56
2012 Shukla-Dave A, Lee NY, Jansen JF, Thaler HT, Stambuk HE, Fury MG, Patel SG, Moreira AL, Sherman E, Karimi S, Wang Y, Kraus D, Shah JP, Pfister DG, Koutcher JA. Dynamic contrast-enhanced magnetic resonance imaging as a predictor of outcome in head-and-neck squamous cell carcinoma patients with nodal metastases. International Journal of Radiation Oncology, Biology, Physics. 82: 1837-44. PMID 21601373 DOI: 10.1016/j.ijrobp.2011.03.006  0.56
2012 Jansen JF, Schöder H, Lee NY, Stambuk HE, Wang Y, Fury MG, Patel SG, Pfister DG, Shah JP, Koutcher JA, Shukla-Dave A. Tumor metabolism and perfusion in head and neck squamous cell carcinoma: pretreatment multimodality imaging with 1H magnetic resonance spectroscopy, dynamic contrast-enhanced MRI, and [18F]FDG-PET. International Journal of Radiation Oncology, Biology, Physics. 82: 299-307. PMID 21236594 DOI: 10.1016/j.ijrobp.2010.11.022  0.56
2011 Darpolor MM, Kennealey PT, Le HC, Zakian KL, Ackerstaff E, Rizwan A, Chen JH, Sambol EB, Schwartz GK, Singer S, Koutcher JA. Preclinical study of treatment response in HCT-116 cells and xenografts with (1) H-decoupled (31) P MRS. Nmr in Biomedicine. 24: 1159-68. PMID 21994185 DOI: 10.1002/nbm.1674  0.56
2011 Serganova I, Rizwan A, Ni X, Thakur SB, Vider J, Russell J, Blasberg R, Koutcher JA. Metabolic imaging: a link between lactate dehydrogenase A, lactate, and tumor phenotype. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 17: 6250-61. PMID 21844011 DOI: 10.1158/1078-0432.CCR-11-0397  0.56
2011 Huang W, Tudorica LA, Li X, Thakur SB, Chen Y, Morris EA, Tagge IJ, Korenblit ME, Rooney WD, Koutcher JA, Springer CS. Discrimination of benign and malignant breast lesions by using shutter-speed dynamic contrast-enhanced MR imaging. Radiology. 261: 394-403. PMID 21828189 DOI: 10.1148/radiol.11102413  0.56
2011 Gade TP, Motley MW, Beattie BJ, Bhakta R, Boskey AL, Koutcher JA, Mayer-Kuckuk P. Imaging of alkaline phosphatase activity in bone tissue. Plos One. 6: e22608. PMID 21799916 DOI: 10.1371/journal.pone.0022608  0.56
2011 Qi J, Shukla-Dave A, Fong Y, Gönen M, Schwartz LH, Jarnagin WM, Koutcher JA, Zakian KL. 31P MR spectroscopic imaging detects regenerative changes in human liver stimulated by portal vein embolization. Journal of Magnetic Resonance Imaging : Jmri. 34: 336-44. PMID 21780228 DOI: 10.1002/jmri.22616  0.56
2011 Carver BS, Chapinski C, Wongvipat J, Hieronymus H, Chen Y, Chandarlapaty S, Arora VK, Le C, Koutcher J, Scher H, Scardino PT, Rosen N, Sawyers CL. Reciprocal feedback regulation of PI3K and androgen receptor signaling in PTEN-deficient prostate cancer. Cancer Cell. 19: 575-86. PMID 21575859 DOI: 10.1016/j.ccr.2011.04.008  0.56
2011 Thakur SB, Brennan SB, Ishill NM, Morris EA, Liberman L, Dershaw DD, Bartella L, Koutcher JA, Huang W. Diagnostic usefulness of water-to-fat ratio and choline concentration in malignant and benign breast lesions and normal breast parenchyma: an in vivo (1) H MRS study. Journal of Magnetic Resonance Imaging : Jmri. 33: 855-63. PMID 21448950 DOI: 10.1002/jmri.22493  0.56
2011 Suehiro M, Yang G, Torchon G, Ackerstaff E, Humm J, Koutcher J, Ouerfelli O. Radiosynthesis of the tumor hypoxia marker [18F]TFMISO via O-[18F]trifluoroethylation reveals a striking difference between trifluoroethyl tosylate and iodide in regiochemical reactivity toward oxygen nucleophiles. Bioorganic & Medicinal Chemistry. 19: 2287-97. PMID 21398131 DOI: 10.1016/j.bmc.2011.02.026  0.56
2011 Alrubaiee M, Wu B, Xu M, Cai W, Koutcher JA, Gayen SK. Multi-wavelength diffusive optical tomography using independent component analysis and time reversal algorithms Optics Infobase Conference Papers. DOI: 10.1117/12.889982  0.56
2011 Alrubaiee M, Wu B, Xu M, Cai W, Koutcher JA, Gayen SK. Multi-wavelength diffusive optical tomography using independent component analysis and time reversal algorithms Optics Infobase Conference Papers 0.56
2010 Mazaheri Y, Bokacheva L, Kroon DJ, Akin O, Hricak H, Chamudot D, Fine S, Koutcher JA. Semi-automatic deformable registration of prostate MR images to pathological slices. Journal of Magnetic Resonance Imaging : Jmri. 32: 1149-57. PMID 21031521 DOI: 10.1002/jmri.22347  0.56
2010 Zakian KL, Hricak H, Ishill N, Reuter VE, Eberhardt S, Moskowitz CS, Shukla-Dave A, Wang L, Scardino PT, Eastham JA, Koutcher JA. An exploratory study of endorectal magnetic resonance imaging and spectroscopy of the prostate as preoperative predictive biomarkers of biochemical relapse after radical prostatectomy. The Journal of Urology. 184: 2320-7. PMID 20952035 DOI: 10.1016/j.juro.2010.07.037  0.56
2010 Jansen JF, Koutcher JA, Shukla-Dave A. Non-invasive imaging of angiogenesis in head and neck squamous cell carcinoma. Angiogenesis. 13: 149-60. PMID 20383743 DOI: 10.1007/s10456-010-9167-z  0.56
2010 Chen JH, Le HC, Koutcher JA, Singer S. Fat-free MRI based on magnetization exchange. Magnetic Resonance in Medicine. 63: 713-8. PMID 20146235 DOI: 10.1002/mrm.22208  0.56
2010 Jansen JFA, Stambuk HE, Koutcher JA, Shukla-Dave A. Non-gaussian analysis of diffusion-weighted MR imaging in head and neck squamous cell carcinoma: A feasibility study American Journal of Neuroradiology. 31: 741-748. PMID 20037133 DOI: 10.3174/ajnr.A1919  0.56
2010 Lockhart AC, Rothenberg ML, Dupont J, Cooper W, Chevalier P, Sternas L, Buzenet G, Koehler E, Sosman JA, Schwartz LH, Gultekin DH, Koutcher JA, Donnelly EF, Andal R, Dancy I, et al. Phase I study of intravenous vascular endothelial growth factor trap, aflibercept, in patients with advanced solid tumors. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 28: 207-14. PMID 19949018 DOI: 10.1200/JCO.2009.22.9237  0.56
2010 Jansen JF, Schöder H, Lee NY, Wang Y, Pfister DG, Fury MG, Stambuk HE, Humm JL, Koutcher JA, Shukla-Dave A. Noninvasive assessment of tumor microenvironment using dynamic contrast-enhanced magnetic resonance imaging and 18F-fluoromisonidazole positron emission tomography imaging in neck nodal metastases. International Journal of Radiation Oncology, Biology, Physics. 77: 1403-10. PMID 19906496 DOI: 10.1016/j.ijrobp.2009.07.009  0.56
2009 Le HC, Lupu M, Kotedia K, Rosen N, Solit D, Koutcher JA. Proton MRS detects metabolic changes in hormone sensitive and resistant human prostate cancer models CWR22 and CWR22r Magnetic Resonance in Medicine. 62: 1112-1119. PMID 19780165 DOI: 10.1002/mrm.22137  0.56
2009 Regales L, Gong Y, Shen R, de Stanchina E, Vivanco I, Goel A, Koutcher JA, Spassova M, Ouerfelli O, Mellinghoff IK, Zakowski MF, Politi KA, Pao W. Dual targeting of EGFR can overcome a major drug resistance mutation in mouse models of EGFR mutant lung cancer. The Journal of Clinical Investigation. 119: 3000-10. PMID 19759520 DOI: 10.1172/JCI38746  0.56
2009 Yang KM, Russell J, Lupu ME, Cho H, Li XF, Koutcher JA, Ling CC. Atrasentan (ABT-627) enhances perfusion and reduces hypoxia in a human tumor xenograft model. Cancer Biology & Therapy. 8: 1940-6. PMID 19717985 DOI: 10.4161/cbt.8.20.9595  0.56
2009 Mazaheri Y, Hricak H, Fine SW, Akin O, Shukla-Dave A, Ishill NM, Moskowitz CS, Grater JE, Reuter VE, Zakian KL, Touijer KA, Koutcher JA. Prostate tumor volume measurement with combined T2-weighted imaging and diffusion-weighted MR: correlation with pathologic tumor volume. Radiology. 252: 449-57. PMID 19703883 DOI: 10.1148/radiol.2523081423  0.56
2009 Chen Z, Carracedo A, Lin HK, Koutcher JA, Behrendt N, Egia A, Alimonti A, Carver BS, Gerald W, Teruya-Feldstein J, Loda M, Pandolfi PP. Differential p53-independent outcomes of p19(Arf) loss in oncogenesis. Science Signaling. 2: ra44. PMID 19690330 DOI: 10.1126/scisignal.2000053  0.56
2009 Silberhumer GR, Zakian K, Malhotra S, Brader P, Gönen M, Koutcher J, Fong Y. Relationship between 31P metabolites and oncolytic viral therapy sensitivity in human colorectal cancer xenografts British Journal of Surgery. 96: 809-816. PMID 19526622 DOI: 10.1002/bjs.6604  0.56
2009 Thakur SB, Yaligar J, Koutcher JA. In vivo lactate signal enhancement using binomial spectral-selective pulses in selective MQ coherence (SS-SelMQC) spectroscopy Magnetic Resonance in Medicine. 62: 591-598. PMID 19526486 DOI: 10.1002/mrm.22065  0.56
2009 Hernando E, Sarmentero-Estrada J, Koppie T, Belda-Iniesta C, Ramírez de Molina V, Cejas P, Ozu C, Le C, Sánchez JJ, González-Barón M, Koutcher J, Cordón-Cardó C, Bochner BH, Lacal JC, Ramírez de Molina A. A critical role for choline kinase-alpha in the aggressiveness of bladder carcinomas. Oncogene. 28: 2425-35. PMID 19448670 DOI: 10.1038/onc.2009.91  0.56
2009 Xing L, Sun X, Deng X, Kotedia K, Urano M, Koutcher JA, Ling CC, Li GC. Expression of the bifunctional suicide gene CDUPRT increases radiosensitization and bystander effect of 5-FC in prostate cancer cells. Radiotherapy and Oncology : Journal of the European Society For Therapeutic Radiology and Oncology. 92: 345-52. PMID 19433338 DOI: 10.1016/j.radonc.2009.04.003  0.56
2009 Beattie BJ, Klose AD, Le CH, Longo VA, Dobrenkov K, Vider J, Koutcher JA, Blasberg RG. Registration of planar bioluminescence to magnetic resonance and x-ray computed tomography images as a platform for the development of bioluminescence tomography reconstruction algorithms. Journal of Biomedical Optics. 14: 024045. PMID 19405773 DOI: 10.1117/1.3120495  0.56
2009 Shukla-Dave A, Lee N, Stambuk H, Wang Y, Huang W, Thaler HT, Patel SG, Shah JP, Koutcher JA. Average arterial input function for quantitative dynamic contrast enhanced magnetic resonance imaging of neck nodal metastases. Bmc Medical Physics. 9: 4. PMID 19351382 DOI: 10.1186/1756-6649-9-4  0.56
2009 Huang W, Wang Y, Panicek DM, Schwartz LH, Koutcher JA. Feasibility of using limited-population-based average R10 for pharmacokinetic modeling of osteosarcoma dynamic contrast-enhanced magnetic resonance imaging data. Magnetic Resonance Imaging. 27: 852-8. PMID 19282123 DOI: 10.1016/j.mri.2009.01.020  0.56
2009 Cho H, Ackerstaff E, Carlin S, Lupu ME, Wang Y, Rizwan A, O'Donoghue J, Ling CC, Humm JL, Zanzonico PB, Koutcher JA. Noninvasive multimodality imaging of the tumor microenvironment: registered dynamic magnetic resonance imaging and positron emission tomography studies of a preclinical tumor model of tumor hypoxia. Neoplasia (New York, N.Y.). 11: 247-59, 2p following. PMID 19242606 DOI: 10.1593/neo.81360  0.56
2009 Gade TP, Buchanan IM, Motley MW, Mazaheri Y, Spees WM, Koutcher JA. Imaging intratumoral convection: pressure-dependent enhancement in chemotherapeutic delivery to solid tumors. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 15: 247-55. PMID 19118052 DOI: 10.1158/1078-0432.CCR-08-0611  0.56
2009 Brame RS, Zaider M, Zakian KL, Koutcher JA, Shukla-Dave A, Reuter VE, Zelefsky MJ, Scardino PT, Hricak H. Regarding the focal treatment of prostate cancer: inference of the Gleason grade from magnetic resonance spectroscopic imaging. International Journal of Radiation Oncology, Biology, Physics. 74: 110-4. PMID 18990509 DOI: 10.1016/j.ijrobp.2008.07.055  0.56
2008 Smith MA, Koutcher JA, Zakian KL. J-difference lactate editing at 3.0 Tesla in the presence of strong lipids. Journal of Magnetic Resonance Imaging : Jmri. 28: 1492-8. PMID 19025937 DOI: 10.1002/jmri.21584  0.56
2008 Zakian KL, Shukla-Dave A, Ackerstaff E, Hricak H, Koutcher JA. 1H magnetic resonance spectroscopy of prostate cancer: biomarkers for tumor characterization. Cancer Biomarkers : Section a of Disease Markers. 4: 263-76. PMID 18957715  0.56
2008 Zhang M, Huang M, Le C, Zanzonico PB, Claus F, Kolbert KS, Martin K, Ling CC, Koutcher JA, Humm JL. Accuracy and reproducibility of tumor positioning during prolonged and multi-modality animal imaging studies. Physics in Medicine and Biology. 53: 5867-82. PMID 18827321 DOI: 10.1088/0031-9155/53/20/021  0.56
2008 Xing L, Deng X, Kotedia K, Ackerstaff E, Ponomarev V, Clifton Ling C, Koutcher JA, Li GC. Non-invasive molecular and functional imaging of cytosine deaminase and uracil phosphoribosyltransferase fused with red fluorescence protein. Acta Oncologica (Stockholm, Sweden). 47: 1211-20. PMID 18661431 DOI: 10.1080/02841860802256475  0.56
2008 Wang Y, Huang W, Panicek DM, Schwartz LH, Koutcher JA. Feasibility of using limited-population-based arterial input function for pharmacokinetic modeling of osteosarcoma dynamic contrast-enhanced MRI data. Magnetic Resonance in Medicine. 59: 1183-9. PMID 18429032 DOI: 10.1002/mrm.21432  0.56
2008 Gade TP, Koutcher JA, Spees WM, Beattie BJ, Ponomarev V, Doubrovin M, Buchanan IM, Beresten T, Zakian KL, Le HC, Tong WP, Mayer-Kuckuk P, Blasberg RG, Gelovani JG. Imaging transgene activity in vivo. Cancer Research. 68: 2878-84. PMID 18413756 DOI: 10.1158/0008-5472.CAN-07-6028  0.56
2008 Mazaheri Y, Shukla-Dave A, Hricak H, Fine SW, Zhang J, Inurrigarro G, Moskowitz CS, Ishill NM, Reuter VE, Touijer K, Zakian KL, Koutcher JA. Prostate cancer: identification with combined diffusion-weighted MR imaging and 3D 1H MR spectroscopic imaging--correlation with pathologic findings. Radiology. 246: 480-8. PMID 18227542 DOI: 10.1148/radiol.2462070368  0.56
2007 Shukla-Dave A, Hricak H, Moskowitz C, Ishill N, Akin O, Kuroiwa K, Spector J, Kumar M, Reuter VE, Koutcher JA, Zakian KL. Detection of prostate cancer with MR spectroscopic imaging: an expanded paradigm incorporating polyamines. Radiology. 245: 499-506. PMID 17890357 DOI: 10.1148/radiol.2452062201  0.56
2007 Regales L, Balak MN, Gong Y, Politi K, Sawai A, Le C, Koutcher JA, Solit DB, Rosen N, Zakowski MF, Pao W. Development of new mouse lung tumor models expressing EGFR T790M mutants associated with clinical resistance to kinase inhibitors. Plos One. 2: e810. PMID 17726540 DOI: 10.1371/journal.pone.0000810  0.56
2007 Procissi D, Claus F, Burgman P, Koziorowski J, Chapman JD, Thakur SB, Matei C, Ling CC, Koutcher JA. In vivo 19F magnetic resonance spectroscopy and chemical shift imaging of tri-fluoro-nitroimidazole as a potential hypoxia reporter in solid tumors. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 13: 3738-47. PMID 17575240 DOI: 10.1158/1078-0432.CCR-06-1563  0.56
2007 Beattie BJ, Förster GJ, Govantes R, Le CH, Longo VA, Zanzonico PB, Bidaut L, Blasberg RG, Koutcher JA. Multimodality registration without a dedicated multimodality scanner. Molecular Imaging. 6: 108-20. PMID 17445505 DOI: 10.2310/7290.2007.00008  0.56
2007 Shukla-Dave A, Hricak H, Kattan MW, Pucar D, Kuroiwa K, Chen HN, Spector J, Koutcher JA, Zakian KL, Scardino PT. The utility of magnetic resonance imaging and spectroscopy for predicting insignificant prostate cancer: an initial analysis. Bju International. 99: 786-93. PMID 17223922 DOI: 10.1111/j.1464-410X.2007.06689.x  0.56
2006 Muruganandham M, Lupu M, Dyke JP, Matei C, Linn M, Packman K, Kolinsky K, Higgins B, Koutcher JA. Preclinical evaluation of tumor microvascular response to a novel antiangiogenic/antitumor agent RO0281501 by dynamic contrast-enhanced MRI at 1.5 T. Molecular Cancer Therapeutics. 5: 1950-7. PMID 16928815 DOI: 10.1158/1535-7163.MCT-06-0010  0.56
2006 Trotman LC, Alimonti A, Scaglioni PP, Koutcher JA, Cordon-Cardo C, Pandolfi PP. Identification of a tumour suppressor network opposing nuclear Akt function. Nature. 441: 523-7. PMID 16680151 DOI: 10.1038/nature04809  0.56
2006 Thakur SB, Karimi S, Dunkel IJ, Koutcher JA, Huang W. Longitudinal MR spectroscopic imaging of pediatric diffuse pontine tumors to assess tumor aggression and progression. Ajnr. American Journal of Neuroradiology. 27: 806-9. PMID 16611768  0.56
2006 Chang J, Thakur S, Perera G, Kowalski A, Huang W, Karimi S, Hunt M, Koutcher J, Fuks Z, Amols H, Narayana A. Image-fusion of MR spectroscopic images for treatment planning of gliomas. Medical Physics. 33: 32-40. PMID 16485406 DOI: 10.1118/1.2128497  0.56
2005 Gade TP, Hassen W, Santos E, Gunset G, Saudemont A, Gong MC, Brentjens R, Zhong XS, Stephan M, Stefanski J, Lyddane C, Osborne JR, Buchanan IM, Hall SJ, Heston WD, ... ... Koutcher JA, et al. Targeted elimination of prostate cancer by genetically directed human T lymphocytes. Cancer Research. 65: 9080-8. PMID 16204083 DOI: 10.1158/0008-5472.CAN-05-0436  0.56
2005 Alrubaiee M, Gayen SK, Alfano RR, Koutcher JA. Spectral and temporal near-infrared imaging of ex vivo cancerous and normal human breast tissues. Technology in Cancer Research & Treatment. 4: 457-70. PMID 16173818  0.56
2005 Zakian KL, Koutcher JA, Malhotra S, Thaler H, Jarnagin W, Schwartz L, Fong Y. Liver regeneration in humans is characterized by significant changes in cellular phosphorus metabolism: assessment using proton-decoupled 31P-magnetic resonance spectroscopic imaging. Magnetic Resonance in Medicine. 54: 264-71. PMID 16032692 DOI: 10.1002/mrm.20560  0.56
2005 Pucar D, Shukla-Dave A, Hricak H, Moskowitz CS, Kuroiwa K, Olgac S, Ebora LE, Scardino PT, Koutcher JA, Zakian KL. Prostate cancer: correlation of MR imaging and MR spectroscopy with pathologic findings after radiation therapy-initial experience. Radiology. 236: 545-53. PMID 15972335 DOI: 10.1148/radiol.2362040739  0.56
2005 Hu X, Pandolfi PP, Li Y, Koutcher JA, Rosenblum M, Holland EC. mTOR promotes survival and astrocytic characteristics induced by Pten/AKT signaling in glioblastoma. Neoplasia (New York, N.Y.). 7: 356-68. PMID 15967113 DOI: 10.1593/neo.04595  0.56
2005 Mayer-Kuckuk P, Gade TP, Buchanan IM, Doubrovin M, Ageyeva L, Bertino JR, Boskey AL, Blasberg RG, Koutcher JA, Banerjee D. High-resolution imaging of bone precursor cells within the intact bone marrow cavity of living mice. Molecular Therapy : the Journal of the American Society of Gene Therapy. 12: 33-41. PMID 15963918 DOI: 10.1016/j.ymthe.2005.02.018  0.56
2005 Muruganandham M, Alfieri AA, Matei C, Chen Y, Sukenick G, Schemainda I, Hasmann M, Saltz LB, Koutcher JA. Metabolic signatures associated with a NAD synthesis inhibitor-induced tumor apoptosis identified by 1H-decoupled-31P magnetic resonance spectroscopy. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 11: 3503-13. PMID 15867253 DOI: 10.1158/1078-0432.CCR-04-1399  0.56
2005 Spees WM, Gade TPF, Yang G, Tong WP, Bornmann WG, Gorlick R, Koutcher JA. An 19F magnetic resonance-based in vivo assay of solid tumor methotrexate resistance: Proof of principle Clinical Cancer Research. 11: 1454-1461. PMID 15746046 DOI: 10.1158/1078-0432.CCR-04-1439  0.56
2005 Zakian KL, Sircar K, Hricak H, Chen HN, Shukla-Dave A, Eberhardt S, Muruganandham M, Ebora L, Kattan MW, Reuter VE, Scardino PT, Koutcher JA. Correlation of proton MR spectroscopic imaging with gleason score based on step-section pathologic analysis after radical prostatectomy. Radiology. 234: 804-14. PMID 15734935 DOI: 10.1148/radiol.2343040363  0.56
2005 Raizer JJ, Koutcher JA, Abrey LE, Panageas KS, DeAngelis LM, Lis E, Xu S, Zakian KL. Proton magnetic resonance spectroscopy in immunocompetent patients with primary central nervous system lymphoma Journal of Neuro-Oncology. 71: 173-180. PMID 15690135 DOI: 10.1007/s11060-004-1360-8  0.56
2005 Lewis BC, Klimstra DS, Socci ND, Xu S, Koutcher JA, Varmus HE. The absence of p53 promotes metastasis in a novel somatic mouse model for hepatocellular carcinoma. Molecular and Cellular Biology. 25: 1228-37. PMID 15684377 DOI: 10.1128/MCB.25.4.1228-1237.2005  0.56
2005 Yankeelov TE, Rooney WD, Huang W, Dyke JP, Li X, Tudorica A, Lee JH, Koutcher JA, Springer CS. Evidence for shutter-speed variation in CR bolus-tracking studies of human pathology. Nmr in Biomedicine. 18: 173-85. PMID 15578708 DOI: 10.1002/nbm.938  0.56
2004 Pucar D, Koutcher JA, Shah A, Dyke JP, Schwartz L, Thaler H, Kurhanewicz J, Scardino PT, Kelly WK, Hricak H, Zakian KL. Preliminary assessment of magnetic resonance spectroscopic imaging in predicting treatment outcome in patients with prostate cancer at high risk for relapse. Clinical Prostate Cancer. 3: 174-81. PMID 15636684  0.56
2004 Muruganandham M, Koutcher JA, Pizzorno G, He Q. In vivo tumor lactate relaxation measurements by selective multiple-quantum-coherence (Sel-MQC) transfer. Magnetic Resonance in Medicine. 52: 902-6. PMID 15389963 DOI: 10.1002/mrm.20206  0.56
2004 Hoang BH, Dyke JP, Koutcher JA, Huvos AG, Mizobuchi H, Mazza BA, Gorlick R, Healey JH. VEGF expression in osteosarcoma correlates with vascular permeability by dynamic MRI. Clinical Orthopaedics and Related Research. 32-8. PMID 15346048 DOI: 10.1097/01.blo.0000141492.52166.20  0.56
2004 Shih AH, Dai C, Hu X, Rosenblum MK, Koutcher JA, Holland EC. Dose-dependent effects of platelet-derived growth factor-B on glial tumorigenesis. Cancer Research. 64: 4783-9. PMID 15256447 DOI: 10.1158/0008-5472.CAN-03-3831  0.56
2004 Gade TP, Spees WM, Le HC, Zakian KL, Ponomarev V, Doubrovin M, Gelovani JG, Koutcher JA. In vivo 5-fluorouracil and fluoronucleotide T1 relaxation time measurements using the variable nutation angle method. Magnetic Resonance in Medicine. 52: 169-73. PMID 15236381 DOI: 10.1002/mrm.20131  0.56
2004 Shukla-Dave A, Hricak H, Eberhardt SC, Olgac S, Muruganandham M, Scardino PT, Reuter VE, Koutcher JA, Zakian KL. Chronic prostatitis: MR imaging and 1H MR spectroscopic imaging findings--initial observations. Radiology. 231: 717-24. PMID 15163811 DOI: 10.1148/radiol.2313031391  0.56
2004 Zakian KL, Koutcher JA. Magnetic resonance spectroscopy and clinical cancer prognosis. Academic Radiology. 11: 365-7. PMID 15109008 DOI: 10.1016/j.acra.2004.02.004  0.56
2003 Zakian KL, Shukla-Dave A, Meyers P, Gorlick R, Healey J, Thaler HT, Huvos AG, Panicek DM, Koutcher JA. Identification of prognostic markers in bone sarcomas using proton-decoupled phosphorus magnetic resonance spectroscopy. Cancer Research. 63: 9042-7. PMID 14695223  0.56
2003 Trotman LC, Niki M, Dotan ZA, Koutcher JA, Di Cristofano A, Xiao A, Khoo AS, Roy-Burman P, Greenberg NM, Van Dyke T, Cordon-Cardo C, Pandolfi PP. Pten dose dictates cancer progression in the prostate. Plos Biology. 1: E59. PMID 14691534 DOI: 10.1371/journal.pbio.0000059  0.56
2003 Spees WM, Yang G, Veach D, Rubio MB, Koutcher JA, Bornmann W. A fluorine-labeled methotrexate as a probe for monitoring tumor antifolate pharmacokinetics: synthesis, in vitro cytotoxicity, and pilot in vivo 19F magnetic resonance spectra. Molecular Cancer Therapeutics. 2: 933-9. PMID 14578458  0.56
2003 Dyke JP, Zakian KL, Spees WM, Matei C, Chen Y, Mao X, Shungu DC, Koutcher JA. Metabolic response of the CWR22 prostate tumor xenograft after 20 Gy of radiation studied by 1H spectroscopic imaging. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 9: 4529-36. PMID 14555527  0.56
2003 Humm JL, Ballon D, Hu YC, Ruan S, Chui C, Tulipano PK, Erdi A, Koutcher J, Zakian K, Urano M, Zanzonico P, Mattis C, Dyke J, Chen Y, Harrington P, et al. A stereotactic method for the three-dimensional registration of multi-modality biologic images in animals: NMR, PET, histology, and autoradiography. Medical Physics. 30: 2303-14. PMID 14528951 DOI: 10.1118/1.1600738  0.56
2003 Kikuchi E, Xu S, Ohori M, Matei C, Lupu M, Menendez S, Koutcher JA, Bochner BH. Detection and quantitative analysis of early stage orthotopic murine bladder tumor using in vivo magnetic resonance imaging. The Journal of Urology. 170: 1375-8. PMID 14501772 DOI: 10.1097/01.ju.0000075504.13456.41  0.56
2003 Doubrovin M, Ponomarev V, Serganova I, Soghomonian S, Myagawa T, Beresten T, Ageyeva L, Sadelain M, Koutcher J, Blasberg RG, Gelovani Tjuvajev JG. Development of a new reporter gene system-dsRed/Xanthine phosphoribosyltransferase-xanthine for molecular imaging of processes behind the intact blood-brain barrier Molecular Imaging. 2: 93-112. PMID 12964307 DOI: 10.1162/153535003322331984  0.56
2003 Zakian KL, Eberhardt S, Hricak H, Shukla-Dave A, Kleinman S, Muruganandham M, Sircar K, Kattan MW, Reuter VE, Scardino PT, Koutcher JA. Transition zone prostate cancer: metabolic characteristics at 1H MR spectroscopic imaging--initial results. Radiology. 229: 241-7. PMID 12920178 DOI: 10.1148/radiol.2291021383  0.56
2003 Palm S, Enmon RM, Matei C, Kolbert KS, Xu S, Zanzonico PB, Finn RL, Koutcher JA, Larson SM, Sgouros G. Pharmacokinetics and Biodistribution of (86)Y-Trastuzumab for (90)Y dosimetry in an ovarian carcinoma model: correlative MicroPET and MRI. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 44: 1148-55. PMID 12843231  0.56
2003 Dyke JP, Panicek DM, Healey JH, Meyers PA, Huvos AG, Schwartz LH, Thaler HT, Tofts PS, Gorlick R, Koutcher JA, Ballon D. Osteogenic and Ewing sarcomas: estimation of necrotic fraction during induction chemotherapy with dynamic contrast-enhanced MR imaging. Radiology. 228: 271-8. PMID 12832588 DOI: 10.1148/radiol.2281011651  0.56
2003 Kolbert KS, Watson T, Matei C, Xu S, Koutcher JA, Sgouros G. Murine S factors for liver, spleen, and kidney. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 44: 784-91. PMID 12732681  0.56
2003 Mayer-Kuckuk P, Doubrovin M, Gusani NJ, Gade T, Balatoni J, Akhurst T, Finn R, Fong Y, Koutcher JA, Larson S, Blasberg R, Tjuvajev JG, Bertino JR, Banerjee D. Imaging of dihydrofolate reductase fusion gene expression in xenografts of human liver metastases of colorectal cancer in living rats. European Journal of Nuclear Medicine and Molecular Imaging. 30: 1281-91. PMID 12664136 DOI: 10.1007/s00259-003-1143-z  0.56
2003 Xu S, Gade TP, Matei C, Zakian K, Alfieri AA, Hu X, Holland EC, Soghomonian S, Tjuvajev J, Ballon D, Koutcher JA. In vivo multiple-mouse imaging at 1.5 T. Magnetic Resonance in Medicine. 49: 551-7. PMID 12594759 DOI: 10.1002/mrm.10397  0.56
2003 Alrubaiee M, Gayen SK, Koutcher JA, Alfano RR. Cancerous and normal human tissues investigated by near-infrared time-resolved and spectroscopic imaging techniques Proceedings of Spie - the International Society For Optical Engineering. 4955: 199-202. DOI: 10.1117/12.477346  0.56
2002 Koutcher JA, Hu X, Xu S, Gade TP, Leeds N, Zhou XJ, Zagzag D, Holland EC. MRI of mouse models for gliomas shows similarities to humans and can be used to identify mice for preclinical trials. Neoplasia (New York, N.Y.). 4: 480-5. PMID 12407441 DOI: 10.1038/sj.neo.7900269  0.56
2002 Urano M, Chen Y, Humm J, Koutcher JA, Zanzonico P, Ling C. Measurements of tumor tissue oxygen tension using a time-resolved luminescence-based optical oxylite probe: comparison with a paired survival assay. Radiation Research. 158: 167-73. PMID 12105986  0.56
2002 Yang Y, Celmer EJ, Koutcher JA, Alfano RR. DNA and protein changes caused by disease in human breast tissues probed by the Kubelka-Munk spectral functional. Photochemistry and Photobiology. 75: 627-32. PMID 12081325 DOI: 10.1562/0031-8655(2002)075<0627:DAPCCB>2.0.CO;2  0.56
2002 Shukla-Dave A, Poptani H, Loevner LA, Mancuso A, Serrai H, Rosenthal DI, Kilger AM, Nelson DS, Zakian KL, Arias-Mendoza F, Rijpkema M, Koutcher JA, Brown TR, Heerschap A, Glickson JD. Prediction of treatment response of head and neck cancers with P-31 MR spectroscopy from pretreatment relative phosphomonoester levels. Academic Radiology. 9: 688-94. PMID 12061743 DOI: 10.1016/S1076-6332(03)80314-8  0.56
2001 Pevsner PH, Eichenbaum JW, Miller DC, Pivawer G, Eichenbaum KD, Stern A, Zakian KL, Koutcher JA. A photothrombotic model of small early ischemic infarcts in the rat brain with histologic and MRI correlation Journal of Pharmacological and Toxicological Methods. 45: 227-233. PMID 11755387 DOI: 10.1016/S1056-8719(01)00153-8  0.56
2001 Yang Y, Celmer EJ, Koutcher JA, Alfano RR. UV reflectance spectroscopy probes DNA and protein changes in human breast tissues Journal of Clinical Laser Medicine and Surgery. 19: 35-39. PMID 11547817  0.56
2001 Kalderon N, Xu S, Koutcher JA, Fuks Z. Fractionated radiation facilitates repair and functional motor recovery after spinal cord transection in rat Brain Research. 904: 199-207. PMID 11406117 DOI: 10.1016/S0006-8993(01)02402-7  0.56
2001 Dai J, Shen R, Sumitomo M, Goldberg JS, Geng Y, Navarro D, Xu S, Koutcher JA, Garzotto M, Powell CT, Nanus DM. Tumor-suppressive effects of neutral endopeptidase in androgen-independent prostate cancer cells. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 7: 1370-7. PMID 11350908  0.56
2001 Martin DS, Spriggs D, Koutcher JA. A concomitant atp-depleting strategy markedly enhances anticancer agent activity Apoptosis. 6: 125-131. PMID 11321035 DOI: 10.1023/A:1009692631748  0.56
2001 Xu S, Zakian K, Thaler H, Matei C, Alfieri A, Chen Y, Koutcher JA. Effects of Motexafin gadolinium on tumor metabolism and radiation sensitivity International Journal of Radiation Oncology Biology Physics. 49: 1381-1390. PMID 11286846 DOI: 10.1016/S0360-3016(00)01566-2  0.56
2001 Zakian KL, Koutcher JA, Ballon D, Hricak H, Ling CC. Developments in nuclear magnetic resonance imaging and spectroscopy: Application to radiation oncology Seminars in Radiation Oncology. 11: 3-15. PMID 11146038  0.56
2000 Martin DS, Bertino JR, Koutcher JA. ATP depletion + pyrimidine depletion can markedly enhance cancer therapy: Fresh insight for a new approach Cancer Research. 60: 6776-6783. PMID 11156364  0.56
2000 Koutcher JA, Zakian K, Hricak H, Garnick M, Stone N, Debruyne F, Moul J. Magnetic resonance spectroscopic studies of the prostate Molecular Urology. 4: 143-153. PMID 11062368  0.56
2000 Zelefsky MJ, Cohen G, Zakian KL, Dyke J, Koutcher JA, Hricak H, Schwartz L, Zaider M. Intraoperative conformal optimization for transperineal prostate implantation using magnetic resonance spectroscopic imaging Cancer Journal. 6: 249-255. PMID 11038145  0.56
2000 Evelhoch JL, Gillies RJ, Karczmar GS, Koutcher JA, Maxwell RJ, Nalcioglu O, Raghunand N, Ronen SM, Ross BD, Swartz HM. Applications of magnetic resonance in model systems: cancer therapeutics. Neoplasia (New York, N.Y.). 2: 152-65. PMID 10933074  0.56
2000 Kooby DA, Zakian KL, Challa SN, Matei C, Petrowsky H, Yoo HH, Koutcher JA, Fong Y. Use of phosphorous-31 nuclear magnetic resonance spectroscopy to determine safe timing of chemotherapy after hepatic resection Cancer Research. 60: 3800-3806. PMID 10919653  0.56
2000 Zaider M, Zelefsky MJ, Lee EK, Zakian KL, Amols HI, Dyke J, Cohen G, Hu YC, Endi AK, Chui CS, Koutcher JA. Treatment planning for prostate implants using magnetic-resonance spectroscopy imaging International Journal of Radiation Oncology Biology Physics. 47: 1085-1096. PMID 10863082 DOI: 10.1016/S0360-3016(00)00557-5  0.56
2000 Ling CC, Humm J, Larson S, Amols H, Fuks Z, Leibel S, Koutcher JA. Towards multidimensional radiotherapy (MD-CRT): Biological imaging and biological conformality International Journal of Radiation Oncology Biology Physics. 47: 551-560. PMID 10837935 DOI: 10.1016/S0360-3016(00)00467-3  0.56
2000 Koutcher JA, Motwani M, Zakian KL, Li XK, Matei C, Dyke JP, Ballon D, Yoo HH, Schwartz GK. The in vivo effect of bryostatin-1 on paclitaxel-induced tumor growth, mitotic entry, and blood flow. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 6: 1498-507. PMID 10778982  0.56
2000 Zakian KL, D'Angelica M, Matei C, Yoo HH, Ercolani M, Delman K, Fong Y, Koutcher JA. A quantitative assessment of liver metabolites during jaundice using three dimensional phosphorus chemical shift imaging Magnetic Resonance Imaging. 18: 181-187. PMID 10722978 DOI: 10.1016/S0730-725X(99)00119-8  0.56
1999 Miller RA, Woodburn K, Fan Q, Renschler MF, Sessler JL, Koutcher JA. In vivo animal studies with gadolinium (III) texaphyrin as a radiation enhancer International Journal of Radiation Oncology Biology Physics. 45: 981-989. PMID 10571206 DOI: 10.1016/S0360-3016(99)00274-6  0.56
1999 Tjuvajev JG, Chen SH, Joshi A, Joshi R, Guo ZS, Balatoni J, Ballon D, Koutcher J, Finn R, Woo SL, Blasberg RG. Imaging adenoviral-mediated herpes virus thymidine kinase gene transfer and expression in vivo Cancer Research. 59: 5186-5193. PMID 10537296  0.56
1999 Zakian KL, Koutcher JA, Ballon D. A dual-tuned resonator for proton-decoupled phosphorus-31 chemical shift imaging of the brain Magnetic Resonance in Medicine. 41: 809-815. PMID 10332858 DOI: 10.1002/(SICI)1522-2594(199904)41:4<809::AID-MRM21>3.0.CO;2-8  0.56
1998 Tjuvajev JG, Avril N, Oku T, Sasajima T, Miyagawa T, Joshi R, Safer M, Beattie B, DiResta G, Daghighian F, Augensen F, Koutcher J, Zweit J, Humm J, Larson SM, et al. Imaging herpes virus thymidine kinase gene transfer and expression by positron emission tomography Cancer Research. 58: 4333-4341. PMID 9766661  0.56
1998 Ballon D, Jakubowski AA, Tulipano PK, Graham MC, Schneider E, Aghazadeh B, Chen QS, Koutcher JA. Quantitative assessment of bone marrow hematopoiesis using parametric magnetic resonance imaging. Magnetic Resonance in Medicine. 39: 789-800. PMID 9581611 DOI: 10.1002/mrm.1910390517  0.56
1998 Tjuvajev J, Kolesnikov Y, Joshi R, Sherinski J, Koutcher L, Zhou Y, Matei C, Koutcher J, Kreek MJ, Blasberg R. Anti-neoplastic properties of human corticotropin releasing factor: involvement of the nitric oxide pathway. In Vivo (Athens, Greece). 12: 1-10. PMID 9575420  0.56
1998 Katz A, Savage HE, Zeng F, Rome J, Tang GC, Harris D, Koutcher J, Schantz SP, Alfano RR. Fluorescence ratio mapping system for tissue diagnosis Proceedings of Spie - the International Society For Optical Engineering. 3250: 64-67. DOI: 10.1117/12.305363  0.56
1997 Koutcher JA, Alfieri AA, Thaler H, Matei C, Martin DS. Radiation enhancement by biochemical modulation and 5-fluorouracil International Journal of Radiation Oncology Biology Physics. 39: 1145-1152. PMID 9392557 DOI: 10.1016/S0360-3016(97)00505-1  0.56
1997 Street JC, Szwergold BS, Matei C, Kappler F, Mahmood U, Brown TR, Koutcher JA. Study of the metabolism of choline and phosphatidylcholine in tumors in vivo using phosphonium-choline. Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine. 38: 769-75. PMID 9358451 DOI: 10.1002/mrm.1910380513  0.56
1997 Street JC, Alfieri AA, Koutcher JA. Quantitation of metabolic and radiobiological effects of 6- aminonicotinamide in RIF-1 tumor cells in vitro Cancer Research. 57: 3956-3962. PMID 9307279  0.56
1997 Nord LD, Stolfi RL, Alfieri AA, Netto G, Reuter V, Sternberg SS, Colofiore JR, Koutcher JA, Martin DS. Apoptosis induced in advanced CD8F1-murine mammary tumors by the combination of PALA, MMPR and 6AN precedes tumor regression and is preceded by ATP depletion. Cancer Chemotherapy and Pharmacology. 40: 376-84. PMID 9272113 DOI: 10.1007/s002800050674  0.56
1997 Street JC, Alfieri AA, Traganos F, Koutcher JA. In vivo and ex vivo study of metabolic and cellular effects of 5- fluorouracil chemotherapy in a mouse mammary carcinoma Magnetic Resonance Imaging. 15: 587-596. PMID 9254003 DOI: 10.1016/S0730-725X(97)00013-1  0.56
1997 Heelan RT, Panicek DM, Burt ME, Caravelli JF, Martini N, Bains M, McCormack P, Koutcher JA, Cardini L. Magnetic resonance imaging of the postpneumonectomy chest: Normal and abnormal findings Journal of Thoracic Imaging. 12: 200-208. PMID 9249678  0.56
1997 Schwartz LH, Panicek DM, Doyle MV, Ginsberg MS, Herman SK, Koutcher JA, Brown KT, Getrajdman GI, Burt M. Comparison of two algorithms and their associated charges when evaluating adrenal masses in patients with malignancies. Ajr. American Journal of Roentgenology. 168: 1575-8. PMID 9168729 DOI: 10.2214/ajr.168.6.9168729  0.56
1997 Koutcher JA, Alfieri AA, Tsai JC, Matei C, Stolfi RL, Ballon D, Martin DS. Evaluation of chemotherapy and radiation enhancement and 31P NMR spectral changes induced by biochemical modulation Cancer Investigation. 15: 111-120. PMID 9095206  0.56
1997 Street JC, Koutcher JA. Effect of radiotherapy and chemotherapy on composition of tumor membrane phospholipids Lipids. 32: 45-49. PMID 9075192 DOI: 10.1007/s11745-997-0007-2  0.56
1996 Koutcher JA, Alfieri AA, Matei C, Meyer KL, Street JC, Martin DS. Effect of 6-aminonicotinamide on the pentose phosphate pathway: 31P NMR and tumor growth delay studies Magnetic Resonance in Medicine. 36: 887-892. PMID 8946354  0.56
1996 Mahmood U, Street JC, Matei C, Ballon D, Martin DS, Koutcher JA. In vivo detection by 31P NMR of pentose phosphate pathway block secondary to biochemical modulation Nmr in Biomedicine. 9: 114-120. PMID 8892397 DOI: 10.1002/(SICI)1099-1492(199605)9:3<114::AID-NBM413>3.0.CO;2-O  0.56
1996 Tjuvajev JG, Finn R, Watanabe K, Joshi R, Oku T, Kennedy J, Beattie B, Koutcher J, Larson S, Blasberg RG. Noninvasive imaging of herpes virus thymidine kinase gene transfer and expression: A potential method for monitoring clinical gene therapy Cancer Research. 56: 4087-4095. PMID 8797571  0.56
1996 Ballon D, Jakubowski AA, Graham MC, Schneider E, Koutcher JA. Spatial mapping of the percentage cellularity in human bone marrow using magnetic resonance imaging Medical Physics. 23: 243-250. PMID 8668106 DOI: 10.1118/1.597796  0.56
1996 Tjuvajev J, Uehara H, Desai R, Beattie B, Matei C, Zhou Y, Kreek MJ, Koutcher J, Blasberg R. Corticotropin-releasing factor decreases vasogenic brain edema. Cancer Research. 56: 1352-60. PMID 8640825  0.56
1996 Street JC, Mahmood U, Ballon D, Alfieri AA, Koutcher JA. 13C and 31P NMR investigation of effect of 6-Aminonicotinamide on metabolism of RIF-1 tumor cells in vitro Journal of Biological Chemistry. 271: 4113-4119. PMID 8626749  0.56
1995 Street JC, Mahmood U, Matei C, Koutcher JA. In vivo and in vitro studies of cyclophosphamide chemotherapy in a mouse mammary carcinoma by 31P NMR spectroscopy. Nmr in Biomedicine. 8: 149-158. PMID 8771089  0.56
1995 Vassallo P, Matei C, Heston WDW, McLachlan SJ, Koutcher JA, Castellino RA. Characterization of reactive versus tumor–bearing lymph nodes with interstitial magnetic resonance lymphography in an animal model Investigative Radiology. 30: 706-711. PMID 8748183  0.56
1995 Merchant TE, Alfieri AA, Glonek T, Koutcher JA. Comparison of relative changes in phosphatic metabolites and phospholipids after irradiation Radiation Research. 142: 29-38. PMID 7899557 DOI: 10.2307/3578964  0.56
1995 Gerweck LE, Koutcher J, Zaidi ST. Energy status parameters, hypoxia fraction and radiocurability across tumor types Acta Oncologica. 34: 335-338. PMID 7779419 DOI: 10.3109/02841869509093985  0.56
1995 Tjuvajev J, Gansbacher B, Desai R, Beattie B, Kaplitt M, Matei C, Koutcher J, Gilboa E, Blasberg R. RG-2 glioma growth attenuation and severe brain edema caused by local production of interleukin-2 and interferon-gamma. Cancer Research. 55: 1902-10. PMID 7728757  0.56
1995 Schwartz LH, Panicek DM, Koutcher JA, Heelan RT, Bains MS, Burt M. Echoplanar MR imaging for characterization of adrenal masses in patients with malignant neoplasms: Preliminary evaluation of calculated T2 relaxation values American Journal of Roentgenology. 164: 911-915. PMID 7726047  0.56
1995 Merchant TE, Schwartz LH, Ballon D, Koutcher JA, Scher HI, Minsky BD. Intracavitary birdcage resonator: applications to the human prostate Journal of Magnetic Resonance Imaging : Jmri. 5: 365-368. PMID 7633116  0.56
1995 Schwartz LH, Panicek DM, Koutcher JA, Brown KT, Getrajdman GI, Heelan RT, Burt M. Adrenal masses in patients with malignancy: Prospective comparison of echo-planar, fast spin-echo, and chemical shift MR imaging Radiology. 197: 421-425. PMID 7480686  0.56
1994 Mahmood U, Alfieri AA, Thaler H, Cowburn D, Koutcher JA. Radiation Dose-dependent Changes in Tumor Metabolism Measured by 31P Nuclear Magnetic Resonance Spectroscopy Cancer Research. 54: 4885-4891. PMID 8069854  0.56
1994 Vassallo P, Matei C, Heston WD, McLachlan SJ, Koutcher JA, Castellino RA. AMI-227-enhanced MR lymphography: usefulness for differentiating reactive from tumor-bearing lymph nodes. Radiology. 193: 501-6. PMID 7972768 DOI: 10.1148/radiology.193.2.7972768  0.56
1993 Koutcher JA, Alfieri AA, Stolfi RL, Devitt ML, Colofiore JR, Nord LD, Martin DS. Potentiation of a three drug chemotherapy regimen by radiation. Cancer Research. 53: 3518-23. PMID 8339257  0.56
1993 Tjuvajev J, Muraki A, Ginos J, Berk J, Koutcher J, Ballon D, Beattie B, Finn R, Blasberg RG. Iododeoxyuridine uptake and retention as a measure of tumor growth Journal of Nuclear Medicine. 34: 1152-1162. PMID 8315494  0.56
1993 Merchant TE, Ballon D, Koutcher JA, Miodownik S, Schwartz L, Minsky BD. A birdcage resonator for intracavitary MR imaging Magnetic Resonance Imaging. 11: 1119-1127. PMID 8271898 DOI: 10.1016/0730-725X(93)90239-A  0.56
1993 Ballon D, Mahmood U, Jakubowski A, Koutcher JA. Resolution enhanced NMR spectroscopy in biological systems via magnetic susceptibility matched sample immersion chambers Magnetic Resonance in Medicine. 30: 754-758. PMID 8139459 DOI: 10.1002/mrm.1910300615  0.56
1992 Mahmood U, Devitt ML, Kocheril PG, Sutanto-Ward E, Ballon D, Sigurdson ER, Koutcher JA. Quantitation of total metastatic tumor volume in the rat liver: correlation of MR and histologic measurements. Journal of Magnetic Resonance Imaging : Jmri. 2: 335-40. PMID 1627869  0.56
1992 Gerweck LE, Koutcher JA, Syed Zaidi TH, Seneviratne T. Energy status in the murine FSaII and MCaIV tumors under aerobic and hypoxic conditions: An in-vivo and in-vitro analysis International Journal of Radiation Oncology, Biology, Physics. 23: 557-561. PMID 1612956 DOI: 10.1016/0360-3016(92)90011-6  0.56
1992 Koutcher JA, Alfieri AA, Devitt ML, Rhee JG, Kornblith AB, Mahmood U, Merchant TE, Cowburn D. Quantitative changes in tumor metabolism, partial pressure of oxygen, and radiobiological oxygenation status postradiation. Cancer Research. 52: 4620-7. PMID 1511430  0.56
1991 Ballon D, Jakubowski A, Gabrilove J, Graham MC, Zakowski M, Sheridan C, Koutcher JA. In vivo measurements of bone marrow cellularity using volume-localized proton NMR spectroscopy Magnetic Resonance in Medicine. 19: 85-95. PMID 2046540  0.56
1991 Koutcher JA, Sawyer RC, Kornblith AB, Stolfi RL, Martin DS, Devitt ML, Cowburn D, Young CW. In vivo monitoring of changes in 5-fluorouracil metabolism induced by methotrexate measured by 19F NMR spectroscopy. Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine. 19: 113-23. PMID 2046526  0.56
1991 Gerweck LE, Rhee JG, Koutcher JA, Song CW, Urano M. Regulation of pH in murine tumor and muscle. Radiation Research. 126: 206-9. PMID 2023990  0.56
1991 Ballon D, Garwood M, Koutcher JA. An analysis of the intrinsic resonance offset dependence of magnetization generated by stimulated echo pulse sequences for noncoupled spins Magnetic Resonance Imaging. 9: 569-575. PMID 1779728 DOI: 10.1016/0730-725X(91)90044-M  0.56
1990 Koutcher JA, Barnett D, Kornblith AB, Cowburn D, Brady TJ, Gerweck LE. Relationship of changes in pH and energy status to hypoxic cell fraction and hyperthermia sensitivity International Journal of Radiation Oncology, Biology, Physics. 18: 1429-1435. PMID 2370193 DOI: 10.1016/0360-3016(90)90318-E  0.56
1990 Koutcher JA, Alfieri AA, Barnett DC, Cowburn DC, Kornblith AB, Kim JH. Changes in 31P nuclear magnetic resonance with tumor growth in radioresistant and radiosensitive tumors Radiation Research. 121: 312-319. PMID 2315448  0.56
1990 Berger SB, Ballon D, Graham M, Underwood MD, Khayata M, Leggiero RD, Koutcher JA, Reis DJ. Magnetic resonance imaging demonstrates that electric stimulation of cerebellar fastigial nucleus reduces cerebral infarction in rats. Stroke; a Journal of Cerebral Circulation. 21: III172-6. PMID 2237978  0.56
1990 Koutcher JA, Ballon D, Graham M, Healey JH, Casper ES, Heelan R, Gerweck LE. 31P NMR spectra of extremity sarcomas: Diversity of metabolic profiles and changes in response to chemotherapy Magnetic Resonance in Medicine. 16: 19-34. PMID 2175008  0.56
1990 Koutcher JA, Alfieri AA, Kornblith AB, Devitt ML, Cowburn D, Ballon D, Kim JH. Changes in radiation sensitization induced by Fluosol-DA as measured by 31P nuclear magnetic resonance spectroscopy. Cancer Research. 50: 7252-6. PMID 2121332  0.56
1990 Ballon D, Graham MC, Miodownik S, Koutcher JA. A 64 MHz half-birdcage resonator for clinical imaging Journal of Magnetic Resonance (1969). 90: 131-140. DOI: 10.1016/0022-2364(90)90371-F  0.56
1989 Gerweck LE, Urano M, Koutcher J, Fellenz MP, Kahn J. Relationship between energy status, hypoxic cell fraction, and hyperthermic sensitivity in a murine fibrosarcoma Radiation Research. 117: 448-458. PMID 2928469  0.56
1989 Ballon D, Graham MC, Miodownik S, Koutcher JA. Doubly tuned solenoidal resonators for small animal imaging and spectroscopy at 1.5 Tesla Magnetic Resonance Imaging. 7: 155-162. PMID 2716483 DOI: 10.1016/0730-725X(89)90699-1  0.56
1989 Holtzman D, McFarland E, Moerland T, Koutcher J, Kushmerick MJ, Neuringer LJ. Brain creatine phosphate and creatine kinase in mice fed an analogue of creatine. Brain Research. 483: 68-77. PMID 2706511 DOI: 10.1016/0006-8993(89)90035-8  0.56
1988 Koutcher JA, Fellenz MP, Vaupel PW, Gerweck LE. FSAII Mouse Tumor Metabolic Changes with Different Doses of Glucose Measured by 31 P Nuclear Magnetic Resonance Cancer Research. 48: 5917-5921. PMID 3139286  0.56
1988 Ballon D, Koutcher JA. Nuclear magnetic resonance: Principles and applications to pathology Clinics in Laboratory Medicine. 8: 737-751. PMID 3061731  0.56
1987 Koutcher JA, Okunieff P, Neuringer L, Suit H, Brady T. Size dependent changes in tumor phosphate metabolism after radiation therapy as detected by 31P NMR spectroscopy International Journal of Radiation Oncology, Biology, Physics. 13: 1851-1855. PMID 3679923 DOI: 10.1016/0360-3016(87)90351-8  0.56
1987 Hitzig BM, Johnson DC, McFarland E, Koutcher JA, Kazemi H, Burt CT. Unknown phosphate compounds in tail muscle of intact conscious newts by 31P NMR. Comparative Biochemistry and Physiology. B, Comparative Biochemistry. 86: 537-40. PMID 3595089 DOI: 10.1016/0305-0491(87)90444-5  0.56
1987 Hitzig BM, Prichard JW, Kantor HL, Ellington WR, Ingwall JS, Burt CT, Helman SI, Koutcher J. NMR spectroscopy as an investigative technique in physiology. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 1: 22-31. PMID 3301494  0.56
1987 Okunieff P, Koutcher JA, Suit HD. Authors’ response Investigative Radiology. 22: 619-620.  0.56
1986 Okunieff PG, Koutcher JA, Gerweck L, Mcfarland E, Hitzig B, Urano M, Brady T, Neuringer L, Suit HD. Tumor size dependent changes in a murine fibrosarcoma: Use of in vivo 31P NMR for non-invasive evaluation of tumor metabolic status International Journal of Radiation Oncology, Biology, Physics. 12: 793-799. PMID 3710861 DOI: 10.1016/0360-3016(86)90038-6  0.56
1986 Brady TJ, Koutcher JA. Nuclear magnetic resonance (NMR) in clinical diagnosis Advances in Internal Medicine. 31: 419-446. PMID 3511626  0.56
1986 Burt CT, Koutcher J, Roberts JT, London RE, Chance B. Magnetic resonance spectroscopy of the musculoskeletal system. Radiologic Clinics of North America. 24: 321-31. PMID 3459210  0.56
1985 McFarland E, Koutcher JA, Rosen BR. In vivo 19F NMR imaging Journal of Computer Assisted Tomography. 9: 8-15. PMID 3968284  0.56
1985 Mc Farland E, Koutcher JA, Rosen BR, Teicher B, Brady TJ. In vivo<sup>19</sup>f nmr imaging Journal of Computer Assisted Tomography. 9: 8-15.  0.56
1984 Burt CT, Koutcher JA. Multinuclear NMR studies of naturally occurring nuclei. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 25: 237-48. PMID 6726432  0.56
1984 Koutcher JA, Burt CT. Principles of nuclear magnetic resonance. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 25: 101-11. PMID 6726415  0.56
1984 Koutcher JA, Burt CT, Lauffer RB, Brady TJ. Contrast agents and spectroscopic probes in NMR. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 25: 506-13. PMID 6544819  0.56
1984 Koutcher JA, Burt CT. Principles of imaging by nuclear magnetic resonance. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 25: 371-82. PMID 6321701  0.56
1983 Koutcher JA, Goldsmith M. Nuclear magnetic resonance: Preclinical and clinical studies in tumor detection Critical Reviews in Oncology and Hematology. 1: 93-128. PMID 6397265 DOI: 10.1016/S1040-8428(83)80006-7  0.56
1981 Koutcher JA. Nuclear magnetic resonance New England Journal of Medicine. 305: 1160. PMID 7290131  0.56
1978 Goldsmith M, Koutcher JA, Damadian R. NMR in cancer, XIII: Application of the nmr malignancy index to human mammary tumours British Journal of Cancer. 38: 547-554. PMID 728343 DOI: 10.1038/bjc.1978.243  0.56
1978 Fruchter RG, Goldsmith M, Boyce JG, Nicastri AD, Koutcher J, Damadian R. Nuclear magnetic resonance properties of gynecological tissues. Gynecologic Oncology. 6: 243-55. PMID 669442 DOI: 10.1016/0090-8258(78)90029-X  0.56
1978 Damadian R, Minkoff L, Goldsmith M, Koutcher JA. Field-focusing nuclear magnetic resonance (FONAR) - Formation of chemical scans in man Naturwissenschaften. 65: 250-252. PMID 662021 DOI: 10.1007/BF00368564  0.56
1978 Goldsmith M, Koutcher J, Damadian R. NMR in cancer. XI. Application of the NMR malignancy index to human gastro-intestinal tumors Cancer. 41: 183-191. PMID 626928  0.56
1978 Koutcher JA, Goldsmith M, Damadian R. NMR in cancer. X. A malignancy index to discriminate normal and cancerous tissue Cancer. 41: 174-182. PMID 626927  0.56
1977 Goldsmith M, Koutcher JA, Damadian R. Nuclear magnetic resonance in cancer, XII: Application of nmr malignancy index to human lung tumours British Journal of Cancer. 36: 235-242. PMID 911662 DOI: 10.1038/bjc.1977.183  0.56
1977 Minkoff L, Damadian R, Thomas TE, Hu N, Goldsmith M, Koutcher J, Stanford M. NMR in cancer: XVII. dewar for a 53-inch superconducting NMR magnet Physiological Chemistry and Physics. 9: 101-104. PMID 909947  0.56
1977 Koutcher JA, Damadian R. Spectral differences in the 31P NMR of normal and malignant tissue Physiological Chemistry and Physics. 9: 181-187. PMID 601109  0.56
1976 Damadian R, Minkoff L, Goldsmith M, Stanford M, Koutcher J. Field focusing nuclear magnetic resonance (FONAR): visualization of a tumor in a live animal Science. 194: 1430-1432. PMID 1006309  0.56
1976 Damadian R, Minkoff L, Goldsmith M, Stanford M, Koutcher J. Tumor imaging in a live animal by focusing NMR (FONAR) Physiological Chemistry and Physics. 8: 61-65. PMID 959335  0.56
1976 Koutcher JA, Larkin RH, Williams JR, Kukolich SG. Rotational absorption spectrum of methylene fluoride in the 20-100 cm-1 region Journal of Molecular Spectroscopy. 60: 373-380. DOI: 10.1016/0022-2852(76)90140-5  0.56
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