Year |
Citation |
Score |
2018 |
Ananieva EA, Bostic JN, Torres AA, Glanz HR, McNitt SM, Brenner MK, Boyer MP, Addington AK, Hutson SM. Mice deficient in the mitochondrial branched-chain aminotransferase (BCATm) respond with delayed tumour growth to a challenge with EL-4 lymphoma. British Journal of Cancer. PMID 30318512 DOI: 10.1038/S41416-018-0283-7 |
0.379 |
|
2017 |
Sperringer JE, Addington A, Hutson SM. Branched-Chain Amino Acids and Brain Metabolism. Neurochemical Research. PMID 28417264 DOI: 10.1007/S11064-017-2261-5 |
0.469 |
|
2016 |
Ananieva EA, Van Horn CG, Jones MR, Hutson SM. Liver BCATm transgenic mouse model reveals the important role of the liver in maintaining BCAA homeostasis. The Journal of Nutritional Biochemistry. 40: 132-140. PMID 27886623 DOI: 10.1016/J.Jnutbio.2016.10.014 |
0.365 |
|
2016 |
Conway ME, Hutson SM. BCAA Metabolism and NH3 Homeostasis. Advances in Neurobiology. 13: 99-132. PMID 27885628 DOI: 10.1007/978-3-319-45096-4_5 |
0.388 |
|
2016 |
Ananieva EA, Powell JD, Hutson SM. Leucine Metabolism in T Cell Activation: mTOR Signaling and Beyond. Advances in Nutrition (Bethesda, Md.). 7: 798S-805S. PMID 27422517 DOI: 10.3945/An.115.011221 |
0.323 |
|
2016 |
Conway ME, Hull J, El Hindy M, Taylor SC, El Amraoui F, Paton-Thomas C, White P, Williams M, Ellis HP, Bertoni A, Radlwimmer B, Hutson SM, Kurian KM. Decreased expression of the mitochondrial bcat protein correlates with improved patient survival in idh-wt gliomas. Brain Pathology (Zurich, Switzerland). PMID 27071501 DOI: 10.1111/Bpa.12385 |
0.383 |
|
2016 |
Ashby EL, Kierzkowska M, Hull J, Kehoe PG, Hutson SM, Conway ME. Altered Expression of Human Mitochondrial Branched Chain Aminotransferase in Dementia with Lewy Bodies and Vascular Dementia. Neurochemical Research. PMID 26980008 DOI: 10.1007/S11064-016-1855-7 |
0.322 |
|
2015 |
Neishabouri SH, Hutson SM, Davoodi J. Chronic activation of mTOR complex 1 by branched chain amino acids and organ hypertrophy. Amino Acids. 47: 1167-82. PMID 25721400 DOI: 10.1007/S00726-015-1944-Y |
0.39 |
|
2015 |
Hull J, Patel VB, Hutson SM, Conway ME. New insights into the role of the branched-chain aminotransferase proteins in the human brain. Journal of Neuroscience Research. 93: 987-98. PMID 25639459 DOI: 10.1002/Jnr.23558 |
0.401 |
|
2014 |
Laeger T, Reed SD, Henagan TM, Fernandez DH, Taghavi M, Addington A, Münzberg H, Martin RJ, Hutson SM, Morrison CD. Leucine acts in the brain to suppress food intake but does not function as a physiological signal of low dietary protein. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 307: R310-20. PMID 24898843 DOI: 10.1152/Ajpregu.00116.2014 |
0.314 |
|
2014 |
Tso SC, Gui WJ, Wu CY, Chuang JL, Qi X, Skvora KJ, Dork K, Wallace AL, Morlock LK, Lee BH, Hutson SM, Strom SC, Williams NS, Tambar UK, Wynn RM, et al. Benzothiophene carboxylate derivatives as novel allosteric inhibitors of branched-chain α-ketoacid dehydrogenase kinase. The Journal of Biological Chemistry. 289: 20583-93. PMID 24895126 DOI: 10.1074/Jbc.M114.569251 |
0.412 |
|
2013 |
Tönjes M, Barbus S, Park YJ, Wang W, Schlotter M, Lindroth AM, Pleier SV, Bai AH, Karra D, Piro RM, Felsberg J, Addington A, Lemke D, Weibrecht I, Hovestadt V, ... ... Hutson SM, et al. BCAT1 promotes cell proliferation through amino acid catabolism in gliomas carrying wild-type IDH1. Nature Medicine. 19: 901-8. PMID 23793099 DOI: 10.1038/Nm.3217 |
0.414 |
|
2013 |
Tso SC, Qi X, Gui WJ, Chuang JL, Morlock LK, Wallace AL, Ahmed K, Laxman S, Campeau PM, Lee BH, Hutson SM, Tu BP, Williams NS, Tambar UK, Wynn RM, et al. Structure-based design and mechanisms of allosteric inhibitors for mitochondrial branched-chain α-ketoacid dehydrogenase kinase. Proceedings of the National Academy of Sciences of the United States of America. 110: 9728-33. PMID 23716694 DOI: 10.1073/Pnas.1303220110 |
0.413 |
|
2012 |
Cole JT, Sweatt AJ, Hutson SM. Expression of mitochondrial branched-chain aminotransferase and α-keto-acid dehydrogenase in rat brain: implications for neurotransmitter metabolism. Frontiers in Neuroanatomy. 6: 18. PMID 22654736 DOI: 10.3389/Fnana.2012.00018 |
0.494 |
|
2012 |
Purpera MN, Shen L, Taghavi M, Münzberg H, Martin RJ, Hutson SM, Morrison CD. Impaired branched chain amino acid metabolism alters feeding behavior and increases orexigenic neuropeptide expression in the hypothalamus. The Journal of Endocrinology. 212: 85-94. PMID 21969404 DOI: 10.1530/Joe-11-0270 |
0.351 |
|
2011 |
Hutson SM, Islam MM, Zaganas I. Interaction between glutamate dehydrogenase (GDH) and L-leucine catabolic enzymes: intersecting metabolic pathways. Neurochemistry International. 59: 518-24. PMID 21621574 DOI: 10.1016/J.Neuint.2011.05.001 |
0.502 |
|
2011 |
Brunetti-Pierri N, Lanpher B, Erez A, Ananieva EA, Islam M, Marini JC, Sun Q, Yu C, Hegde M, Li J, Wynn RM, Chuang DT, Hutson S, Lee B. Phenylbutyrate therapy for maple syrup urine disease. Human Molecular Genetics. 20: 631-40. PMID 21098507 DOI: 10.1093/Hmg/Ddq507 |
0.4 |
|
2010 |
Nautiyal M, Sweatt AJ, MacKenzie JA, Mark Payne R, Szucs S, Matalon R, Wallin R, Hutson SM. Neuronal localization of the mitochondrial protein NIPSNAP1 in rat nervous system. The European Journal of Neuroscience. 32: 560-9. PMID 20646061 DOI: 10.1111/J.1460-9568.2010.07326.X |
0.67 |
|
2010 |
Escobar J, Frank JW, Suryawan A, Nguyen HV, Van Horn CG, Hutson SM, Davis TA. Leucine and alpha-ketoisocaproic acid, but not norleucine, stimulate skeletal muscle protein synthesis in neonatal pigs. The Journal of Nutrition. 140: 1418-24. PMID 20534881 DOI: 10.3945/Jn.110.123042 |
0.356 |
|
2010 |
Islam MM, Nautiyal M, Wynn RM, Mobley JA, Chuang DT, Hutson SM. Branched-chain amino acid metabolon: interaction of glutamate dehydrogenase with the mitochondrial branched-chain aminotransferase (BCATm). The Journal of Biological Chemistry. 285: 265-76. PMID 19858196 DOI: 10.1074/Jbc.M109.048777 |
0.723 |
|
2009 |
Li P, Knabe DA, Kim SW, Lynch CJ, Hutson SM, Wu G. Lactating porcine mammary tissue catabolizes branched-chain amino acids for glutamine and aspartate synthesis. The Journal of Nutrition. 139: 1502-9. PMID 19549750 DOI: 10.3945/Jn.109.105957 |
0.449 |
|
2009 |
Coles SJ, Easton P, Sharrod H, Hutson SM, Hancock J, Patel VB, Conway ME. S-Nitrosoglutathione inactivation of the mitochondrial and cytosolic BCAT proteins: S-nitrosation and S-thiolation. Biochemistry. 48: 645-56. PMID 19119849 DOI: 10.1021/Bi801805H |
0.395 |
|
2008 |
Hutson SM, Poole LB, Coles S, Conway ME. Redox regulation and trapping sulfenic acid in the peroxide-sensitive human mitochondrial branched chain aminotransferase. Methods in Molecular Biology (Clifton, N.J.). 476: 139-52. PMID 19157014 DOI: 10.1007/978-1-59745-129-1_10 |
0.478 |
|
2008 |
Walrand S, Short KR, Bigelow ML, Sweatt AJ, Hutson SM, Nair KS. Functional impact of high protein intake on healthy elderly people. American Journal of Physiology. Endocrinology and Metabolism. 295: E921-8. PMID 18697911 DOI: 10.1152/Ajpendo.90536.2008 |
0.335 |
|
2008 |
Conway ME, Coles SJ, Islam MM, Hutson SM. Regulatory control of human cytosolic branched-chain aminotransferase by oxidation and S-glutathionylation and its interactions with redox sensitive neuronal proteins. Biochemistry. 47: 5465-79. PMID 18419134 DOI: 10.1021/Bi800303H |
0.363 |
|
2008 |
Wallin R, Wajih N, Hutson SM. VKORC1: a warfarin-sensitive enzyme in vitamin K metabolism and biosynthesis of vitamin K-dependent blood coagulation factors. Vitamins and Hormones. 78: 227-46. PMID 18374197 DOI: 10.1016/S0083-6729(07)00011-8 |
0.308 |
|
2008 |
LaNoue KF, Kreiger J, Xu Y, Wood M, Berkich DA, Hutson SM. Metabolic influence of gabapentin in brain Journal of Neurochemistry. 81: 25-27. DOI: 10.1046/J.1471-4159.81.S1.11_5.X |
0.365 |
|
2008 |
Martin R, Li S, Zhou J, Morrison C, Hutson S. Blocking of branch chain amino acid metabolism decreases hypothalamic POMC and increases AgRP expression in mice on a low fat diet Appetite. 51: 384. DOI: 10.1016/J.Appet.2008.04.160 |
0.379 |
|
2008 |
Hutson SM, Poole LB, Coles S, Conway ME. Redox regulation and trapping sulphenic acid in the peroxide sensitive human mitochondrial branched chain aminotransferase Methods in Molecular Biology. 476: 139-152. DOI: 10.1007/978-1-59745-129-1_10 |
0.343 |
|
2007 |
She P, Van Horn C, Reid T, Hutson SM, Cooney RN, Lynch CJ. Obesity-related elevations in plasma leucine are associated with alterations in enzymes involved in branched-chain amino acid metabolism. American Journal of Physiology. Endocrinology and Metabolism. 293: E1552-63. PMID 17925455 DOI: 10.1152/Ajpendo.00134.2007 |
0.342 |
|
2007 |
Berkich DA, Ola MS, Cole J, Sweatt AJ, Hutson SM, LaNoue KF. Mitochondrial transport proteins of the brain. Journal of Neuroscience Research. 85: 3367-77. PMID 17847082 DOI: 10.1002/Jnr.21500 |
0.449 |
|
2007 |
She P, Reid TM, Bronson SK, Vary TC, Hajnal A, Lynch CJ, Hutson SM. Disruption of BCATm in mice leads to increased energy expenditure associated with the activation of a futile protein turnover cycle. Cell Metabolism. 6: 181-94. PMID 17767905 DOI: 10.1016/J.Cmet.2007.08.003 |
0.359 |
|
2007 |
Xu Y, Ola MS, Berkich DA, Gardner TW, Barber AJ, Palmieri F, Hutson SM, LaNoue KF. Energy sources for glutamate neurotransmission in the retina: absence of the aspartate/glutamate carrier produces reliance on glycolysis in glia. Journal of Neurochemistry. 101: 120-31. PMID 17394462 DOI: 10.1111/J.1471-4159.2006.04349.X |
0.357 |
|
2007 |
García-Espinosa MA, Wallin R, Hutson SM, Sweatt AJ. Widespread neuronal expression of branched-chain aminotransferase in the CNS: implications for leucine/glutamate metabolism and for signaling by amino acids. Journal of Neurochemistry. 100: 1458-68. PMID 17348860 DOI: 10.1111/J.1471-4159.2006.04332.X |
0.4 |
|
2007 |
Islam MM, Wallin R, Wynn RM, Conway M, Fujii H, Mobley JA, Chuang DT, Hutson SM. A novel branched-chain amino acid metabolon. Protein-protein interactions in a supramolecular complex. The Journal of Biological Chemistry. 282: 11893-903. PMID 17314104 DOI: 10.1074/Jbc.M700198200 |
0.458 |
|
2007 |
Castellano S, Casarosa S, Sweatt AJ, Hutson SM, Bozzi Y. Expression of cytosolic branched chain aminotransferase (BCATc) mRNA in the developing mouse brain. Gene Expression Patterns : Gep. 7: 485-90. PMID 17150414 DOI: 10.1016/J.Modgep.2006.10.010 |
0.382 |
|
2007 |
Wajih N, Hutson SM, Wallin R. Disulfide-dependent protein folding is linked to operation of the vitamin K cycle in the endoplasmic reticulum. A protein disulfide isomerase-VKORC1 redox enzyme complex appears to be responsible for vitamin K1 2,3-epoxide reduction. The Journal of Biological Chemistry. 282: 2626-35. PMID 17124179 DOI: 10.1074/Jbc.M608954200 |
0.345 |
|
2007 |
Lynch CJ, Stanley BA, Stanley AE, Nautiyal M, She P, Hutson SM. Comparison of mitochondrial protein expression in wildtype and mitochondrial branched chain aminotransferase (BCATm) KO mice using isotope coded affinity tags (iTRAQ) The Faseb Journal. 21. DOI: 10.1096/Fasebj.21.5.A458 |
0.65 |
|
2007 |
She P, Bronson S, Van Horn C, Reid T, Lynch C, Hutson SM. BCATm KO mice have elevated branched chain amino acids (BCAAs), a propensity to be lean, and show improvements in endpoints associated with obesity co‐morbidities The Faseb Journal. 21. DOI: 10.1096/Fasebj.21.5.A163-A |
0.337 |
|
2006 |
Hutson SM. The case for regulating indispensable amino acid metabolism: the branched-chain alpha-keto acid dehydrogenase kinase-knockout mouse. The Biochemical Journal. 400: e1-3. PMID 17061958 DOI: 10.1042/Bj20061506 |
0.455 |
|
2006 |
Yennawar NH, Islam MM, Conway M, Wallin R, Hutson SM. Human mitochondrial branched chain aminotransferase isozyme: structural role of the CXXC center in catalysis. The Journal of Biological Chemistry. 281: 39660-71. PMID 17050531 DOI: 10.1074/Jbc.M607552200 |
0.434 |
|
2006 |
Lynch CJ, Gern B, Lloyd C, Hutson SM, Eicher R, Vary TC. Leucine in food mediates some of the postprandial rise in plasma leptin concentrations. American Journal of Physiology. Endocrinology and Metabolism. 291: E621-30. PMID 16638821 DOI: 10.1152/Ajpendo.00462.2005 |
0.324 |
|
2005 |
Pérez-Villaseñor G, Tovar AR, Moranchel AH, Hernández-Pando R, Hutson SM, Torres N. Mitochondrial branched chain aminotransferase gene expression in AS-30D hepatoma rat cells and during liver regeneration after partial hepatectomy in rat. Life Sciences. 78: 334-9. PMID 16194549 DOI: 10.1016/J.Lfs.2005.04.079 |
0.409 |
|
2005 |
Goto M, Miyahara I, Hirotsu K, Conway M, Yennawar N, Islam MM, Hutson SM. Structural determinants for branched-chain aminotransferase isozyme-specific inhibition by the anticonvulsant drug gabapentin. The Journal of Biological Chemistry. 280: 37246-56. PMID 16141215 DOI: 10.1074/Jbc.M506486200 |
0.457 |
|
2005 |
Wajih N, Hutson SM, Owen J, Wallin R. Increased production of functional recombinant human clotting factor IX by baby hamster kidney cells engineered to overexpress VKORC1, the vitamin K 2,3-epoxide-reducing enzyme of the vitamin K cycle. The Journal of Biological Chemistry. 280: 31603-7. PMID 16030016 DOI: 10.1074/Jbc.M505373200 |
0.31 |
|
2005 |
Hutson SM, Sweatt AJ, Lanoue KF. Branched-chain [corrected] amino acid metabolism: implications for establishing safe intakes. The Journal of Nutrition. 135: 1557S-64S. PMID 15930469 DOI: 10.1093/Jn/135.6.1557S |
0.512 |
|
2005 |
Wajih N, Sane DC, Hutson SM, Wallin R. Engineering of a recombinant vitamin K-dependent gamma-carboxylation system with enhanced gamma-carboxyglutamic acid forming capacity: evidence for a functional CXXC redox center in the system. The Journal of Biological Chemistry. 280: 10540-7. PMID 15640149 DOI: 10.1074/Jbc.M413982200 |
0.325 |
|
2005 |
Berkich DA, Xu Y, LaNoue KF, Gruetter R, Hutson SM. Evaluation of brain mitochondrial glutamate and alpha-ketoglutarate transport under physiologic conditions. Journal of Neuroscience Research. 79: 106-13. PMID 15558751 DOI: 10.1002/Jnr.20325 |
0.398 |
|
2004 |
Oz G, Berkich DA, Henry PG, Xu Y, LaNoue K, Hutson SM, Gruetter R. Neuroglial metabolism in the awake rat brain: CO2 fixation increases with brain activity. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 11273-9. PMID 15601933 DOI: 10.1523/Jneurosci.3564-04.2004 |
0.345 |
|
2004 |
Sweatt AJ, Garcia-Espinosa MA, Wallin R, Hutson SM. Branched-chain amino acids and neurotransmitter metabolism: expression of cytosolic branched-chain aminotransferase (BCATc) in the cerebellum and hippocampus. The Journal of Comparative Neurology. 477: 360-70. PMID 15329886 DOI: 10.1002/Cne.20200 |
0.464 |
|
2004 |
Wajih N, Borras T, Xue W, Hutson SM, Wallin R. Processing and transport of matrix gamma-carboxyglutamic acid protein and bone morphogenetic protein-2 in cultured human vascular smooth muscle cells: evidence for an uptake mechanism for serum fetuin. The Journal of Biological Chemistry. 279: 43052-60. PMID 15280384 DOI: 10.1074/Jbc.M407180200 |
0.355 |
|
2004 |
Madeddu F, Naska S, Menna E, Chiellini C, Sweatt AJ, Hutson SM, Benzi L, Maffei M, Maffei L, Bozzi Y. Intraocular delivery of BDNF following visual cortex lesion upregulates cytosolic branched chain aminotransferase (BCATc) in the rat dorsal lateral geniculate nucleus. The European Journal of Neuroscience. 20: 580-6. PMID 15233768 DOI: 10.1111/J.1460-9568.2004.03482.X |
0.33 |
|
2004 |
Conway ME, Poole LB, Hutson SM. Roles for cysteine residues in the regulatory CXXC motif of human mitochondrial branched chain aminotransferase enzyme. Biochemistry. 43: 7356-64. PMID 15182179 DOI: 10.1021/Bi0498050 |
0.358 |
|
2004 |
Wajih N, Sane DC, Hutson SM, Wallin R. The inhibitory effect of calumenin on the vitamin K-dependent gamma-carboxylation system. Characterization of the system in normal and warfarin-resistant rats. The Journal of Biological Chemistry. 279: 25276-83. PMID 15075329 DOI: 10.1074/Jbc.M401645200 |
0.335 |
|
2004 |
Sweatt AJ, Wood M, Suryawan A, Wallin R, Willingham MC, Hutson SM. Branched-chain amino acid catabolism: unique segregation of pathway enzymes in organ systems and peripheral nerves. American Journal of Physiology. Endocrinology and Metabolism. 286: E64-76. PMID 12965870 DOI: 10.1152/Ajpendo.00276.2003 |
0.473 |
|
2003 |
Sweatt A, Sane DC, Hutson SM, Wallin R. Matrix Gla protein (MGP) and bone morphogenetic protein-2 in aortic calcified lesions of aging rats. Journal of Thrombosis and Haemostasis : Jth. 1: 178-85. PMID 12871556 DOI: 10.1046/J.1538-7836.2003.00023.X |
0.307 |
|
2003 |
Lynch CJ, Halle B, Fujii H, Vary TC, Wallin R, Damuni Z, Hutson SM. Potential role of leucine metabolism in the leucine-signaling pathway involving mTOR. American Journal of Physiology. Endocrinology and Metabolism. 285: E854-63. PMID 12812918 DOI: 10.1152/Ajpendo.00153.2003 |
0.386 |
|
2003 |
Conway ME, Yennawar N, Wallin R, Poole LB, Hutson SM. Human mitochondrial branched chain aminotransferase: structural basis for substrate specificity and role of redox active cysteines. Biochimica Et Biophysica Acta. 1647: 61-5. PMID 12686109 DOI: 10.1016/S1570-9639(03)00051-7 |
0.492 |
|
2003 |
Cooper AJ, Bruschi SA, Conway M, Hutson SM. Human mitochondrial and cytosolic branched-chain aminotransferases are cysteine S-conjugate beta-lyases, but turnover leads to inactivation. Biochemical Pharmacology. 65: 181-92. PMID 12504794 DOI: 10.1016/S0006-2952(02)01513-7 |
0.368 |
|
2002 |
Yennawar NH, Conway ME, Yennawar HP, Farber GK, Hutson SM. Crystal structures of human mitochondrial branched chain aminotransferase reaction intermediates: ketimine and pyridoxamine phosphate forms. Biochemistry. 41: 11592-601. PMID 12269802 DOI: 10.1021/Bi020221C |
0.455 |
|
2002 |
Cooper AJ, Conway M, Hutson SM. A continuous 96-well plate spectrophotometric assay for branched-chain amino acid aminotransferases. Analytical Biochemistry. 308: 100-5. PMID 12234469 DOI: 10.1016/S0003-2697(02)00243-9 |
0.437 |
|
2002 |
Lynch CJ, Hutson SM, Patson BJ, Vaval A, Vary TC. Tissue-specific effects of chronic dietary leucine and norleucine supplementation on protein synthesis in rats. American Journal of Physiology. Endocrinology and Metabolism. 283: E824-35. PMID 12217901 DOI: 10.1152/Ajpendo.00085.2002 |
0.401 |
|
2002 |
Conway ME, Yennawar N, Wallin R, Poole LB, Hutson SM. Identification of a peroxide-sensitive redox switch at the CXXC motif in the human mitochondrial branched chain aminotransferase. Biochemistry. 41: 9070-8. PMID 12119021 DOI: 10.1021/Bi020200I |
0.444 |
|
2001 |
DeSantiago S, Torres N, Hutson S, Tovar AR. Induction of expression of branched-chain aminotransferase and alpha-keto acid dehydrogenase in rat tissues during lactation Advances in Experimental Medicine and Biology. 501: 93-99. PMID 11787736 DOI: 10.1007/978-1-4615-1371-1_11 |
0.441 |
|
2001 |
LaNoue KF, Berkich DA, Conway M, Barber AJ, Hu LY, Taylor C, Hutson S. Role of specific aminotransferases in de novo glutamate synthesis and redox shuttling in the retina. Journal of Neuroscience Research. 66: 914-22. PMID 11746419 DOI: 10.1002/Jnr.10064 |
0.445 |
|
2001 |
Torres N, Vargas C, Hernández-Pando R, Orozco H, Hutson SM, Tovar AR. Ontogeny and subcellular localization of rat liver mitochondrial branched chain amino-acid aminotransferase European Journal of Biochemistry. 268: 6132-6139. PMID 11733007 DOI: 10.1046/J.0014-2956.2001.02563.X |
0.352 |
|
2001 |
Hutson S. Structure and function of branched chain aminotransferases. Progress in Nucleic Acid Research and Molecular Biology. 70: 175-206. PMID 11642362 DOI: 10.1016/S0079-6603(01)70017-7 |
0.455 |
|
2001 |
Wallin R, Hutson SM, Cain D, Sweatt A, Sane DC. A molecular mechanism for genetic warfarin resistance in the rat The Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 15: 2542-2544. PMID 11641264 DOI: 10.1096/Fj.01-0337Fje |
0.327 |
|
2001 |
Yennawar N, Dunbar J, Conway M, Hutson S, Farber G. The structure of human mitochondrial branched-chain aminotransferase. Acta Crystallographica Section D-Biological Crystallography. 57: 506-515. PMID 11264579 DOI: 10.1107/S0907444901001925 |
0.452 |
|
2001 |
Lieth E, LaNoue KF, Berkich DA, Xu B, Ratz M, Taylor C, Hutson SM. Nitrogen shuttling between neurons and glial cells during glutamate synthesis Journal of Neurochemistry. 76: 1712-1723. PMID 11259489 DOI: 10.1046/J.1471-4159.2001.00156.X |
0.418 |
|
2001 |
Hutson SM, Lieth E, Lanoue KF. Function of leucine in excitatory neurotransmitter metabolism in the central nervous system Journal of Nutrition. 131. PMID 11238772 DOI: 10.1093/Jn/131.3.846S |
0.422 |
|
2001 |
Bixel M, Shimomura Y, Hutson S, Hamprecht B. Distribution of key enzymes of branched-chain amino acid metabolism in glial and neuronal cells in culture. The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. 49: 407-18. PMID 11181743 |
0.368 |
|
2001 |
Tovar AR, Becerril E, Hernández-Pando R, López G, Suryawan A, Desantiago S, Hutson SM, Torres N. Localization and expression of BCAT during pregnancy and lactation in the rat mammary gland American Journal of Physiology - Endocrinology and Metabolism. 280. PMID 11171603 DOI: 10.1152/Ajpendo.2001.280.3.E480 |
0.335 |
|
2000 |
Drown PM, Torres N, Tovar AR, Davoodi J, Hutson SM. Use of sulfhydryl reagents to investigate branched chain alpha-keto acid transport in mitochondria. Biochimica Et Biophysica Acta. 1468: 273-84. PMID 11018671 DOI: 10.1016/S0005-2736(00)00266-2 |
0.736 |
|
2000 |
Conway ME, Hutson SM. Mammalian branched-chain aminotransferases. Methods in Enzymology. 324: 355-65. PMID 10989444 DOI: 10.1016/S0076-6879(00)24245-6 |
0.363 |
|
2000 |
Kholodilov NG, Neystat M, Oo TF, Hutson SM, Burke RE. Upregulation of cytosolic branched chain aminotransferase in substantia nigra following developmental striatal target injury. Brain Research. Molecular Brain Research. 75: 281-6. PMID 10686349 DOI: 10.1016/S0169-328X(99)00318-6 |
0.328 |
|
1999 |
Faure M, Glomot F, Bledsoe R, Hutson S, Papet I. Purification and cloning of the mitochondrial branched-chain amino acid aminotransferase from sheep placenta. European Journal of Biochemistry. 259: 104-11. PMID 9914481 DOI: 10.1046/j.1432-1327.1999.00009.x |
0.357 |
|
1998 |
Torres N, López G, De Santiago S, Hutson SM, Tovar AR. Dietary protein level regulates expression of the mitochondrial branched-chain aminotransferase in rats. The Journal of Nutrition. 128: 1368-75. PMID 9687558 DOI: 10.1093/Jn/128.8.1368 |
0.35 |
|
1998 |
Cain D, Hutson SM, Wallin R. Warfarin resistance is associated with a protein component of the vitamin K 2,3-epoxide reductase enzyme complex in rat liver Thrombosis and Haemostasis. 80: 128-133. PMID 9684798 DOI: 10.1055/S-0037-1615151 |
0.334 |
|
1998 |
Hutson SM, Berkich D, Drown P, Xu B, Aschner M, LaNoue KF. Role of branched-chain aminotransferase isoenzymes and gabapentin in neurotransmitter metabolism Journal of Neurochemistry. 71: 863-874. PMID 9681479 DOI: 10.1046/J.1471-4159.1998.71020863.X |
0.725 |
|
1998 |
Suryawan A, Hawes JW, Harris RA, Shimomura Y, Jenkins AE, Hutson SM. A molecular model of human branched-chain amino acid metabolism. The American Journal of Clinical Nutrition. 68: 72-81. PMID 9665099 DOI: 10.1093/Ajcn/68.1.72 |
0.479 |
|
1998 |
DeSantiago S, Torres N, Suryawan A, Tovar AR, Hutson SM. Regulation of branched-chain amino acid metabolism in the lactating rat Journal of Nutrition. 128: 1165-1171. PMID 9649601 DOI: 10.1093/Jn/128.7.1165 |
0.45 |
|
1998 |
Davoodi J, Drown PM, Bledsoe RK, Wallin R, Reinhart GD, Hutson SM. Overexpression and characterization of the human mitochondrial and cytosolic branched-chain aminotransferases. The Journal of Biological Chemistry. 273: 4982-9. PMID 9478945 DOI: 10.1074/Jbc.273.9.4982 |
0.728 |
|
1998 |
Suryawan A, Willingham M, Cain D, Wallin R, Hutson SM. Evidence for cell-specific compartmentation of Branched Chain Amino Acid (BCAA) metabolism Faseb Journal. 12. |
0.383 |
|
1997 |
Cain D, Hutson SM, Wallin R. Assembly of the warfarin-sensitive vitamin K 2,3-epoxide reductase enzyme complex in the endoplasmic reticulum membrane Journal of Biological Chemistry. 272: 29068-29075. PMID 9360981 DOI: 10.1074/Jbc.272.46.29068 |
0.345 |
|
1997 |
Bledsoe RK, Dawson PA, Hutson SM. Cloning of the rat and human mitochondrial branched chain aminotransferases (BCAT(m)) Biochimica Et Biophysica Acta - Protein Structure and Molecular Enzymology. 1339: 9-13. PMID 9165094 DOI: 10.1016/S0167-4838(97)00044-7 |
0.394 |
|
1997 |
Bixel MG, Hutson SM, Hamprecht B. Cellular distribution of branched-chain amino acid aminotransferase isoenzymes among rat brain glial cells in culture. The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. 45: 685-94. PMID 9154155 |
0.356 |
|
1996 |
Stanton C, Ross RP, Hutson S, Wallin R. Processing and expression of rat and human clotting factor-X-encoding cDNAs. Gene. 169: 269-73. PMID 8647460 DOI: 10.1016/0378-1119(95)00832-2 |
0.336 |
|
1995 |
Hutson SM, Bledsoe RK, Hall TR, Dawson PA. Cloning and expression of the mammalian cytosolic branched chain aminotransferase isoenzyme. The Journal of Biological Chemistry. 270: 30344-52. PMID 8530459 DOI: 10.1074/Jbc.270.51.30344 |
0.454 |
|
1993 |
Wallin R, Stanton C, Hutson SM. Intracellular maturation of the γ-carboxyglutamic acid (Gla) region in prothrombin coincides with release of the propeptide Biochemical Journal. 291: 723-727. PMID 8489500 DOI: 10.1042/Bj2910723 |
0.345 |
|
1993 |
Hutson SM, Hall TR. Identification of the mitochondrial branched chain aminotransferase as a branched chain alpha-keto acid transport protein. The Journal of Biological Chemistry. 268: 3084-91. PMID 8428987 |
0.331 |
|
1993 |
Hall TR, Wallin R, Reinhart GD, Hutson SM. Branched chain aminotransferase isoenzymes. Purification and characterization of the rat brain isoenzyme. The Journal of Biological Chemistry. 268: 3092-8. PMID 8381418 |
0.397 |
|
1992 |
Hutson SM, Williams GD, Berkich DA, LaNoue KF, Briggs RW. A 31P NMR study of mitochondrial inorganic phosphate visibility: effects of Ca2+, Mn2+, and the pH gradient. Biochemistry. 31: 1322-30. PMID 1736991 DOI: 10.1021/Bi00120A007 |
0.32 |
|
1992 |
Hutson SM, Wallin R, Hall TR. Identification of mitochondrial branched chain aminotransferase and its isoforms in rat tissues Journal of Biological Chemistry. 267: 15681-15686. PMID 1639805 |
0.334 |
|
1990 |
Hutson SM, Roten S, Kaplan RS. Solubilization and functional reconstitution of the branched-chain α-keto acid transporter from rat heart mitochondria Proceedings of the National Academy of Sciences of the United States of America. 87: 1028-1031. PMID 2300569 DOI: 10.1073/Pnas.87.3.1028 |
0.388 |
|
1990 |
Wallin R, Hall TR, Hutson SM. Purification of branched chain aminotransferase from rat heart mitochondria Journal of Biological Chemistry. 265: 6019-6024. PMID 2156837 |
0.328 |
|
1989 |
Hutson SM. Regulation of substrate availability for the branched-chain α-keto acid dehydrogenase enzyme complex Annals of the New York Academy of Sciences. 573: 230-239. PMID 2634347 DOI: 10.1111/J.1749-6632.1989.Tb15000.X |
0.503 |
|
1989 |
Hutson SM, Berkich D, Williams GD, LaNoue KF, Briggs RW. 31P NMR visibility and characterization of rat liver mitochondrial matrix adenine nucleotides. Biochemistry. 28: 4325-32. PMID 2569890 DOI: 10.1021/Bi00436A030 |
0.377 |
|
1989 |
Hutson SM. Transport regulation of branched-chain amino acid oxidation Annals of the New York Academy of Sciences. 573: 405-406. DOI: 10.1111/J.1749-6632.1989.Tb15020.X |
0.415 |
|
1988 |
Hutson SM, Fenstermacher D, Mahar C. Role of mitochondrial transamination in branched chain amino acid metabolism. The Journal of Biological Chemistry. 263: 3618-25. PMID 3346211 |
0.366 |
|
1988 |
Hutson SM. Subcellular distribution of branched-chain aminotransferase activity in rat tissues Journal of Nutrition. 118: 1475-1481. PMID 3210076 DOI: 10.1093/Jn/118.12.1475 |
0.423 |
|
1981 |
Hutson SM, Harper AE. Blood and tissue branched-chain amino and α-keto acid concentrations: Effect of diet, starvation, and disease American Journal of Clinical Nutrition. 34: 173-183. PMID 7211722 DOI: 10.1093/Ajcn/34.2.173 |
0.349 |
|
1977 |
Van Dop C, Hutson SM, Lardy HA. Pyruvate metabolism in bovine epididymal spermatozoa. The Journal of Biological Chemistry. 252: 1303-8. PMID 838718 |
0.336 |
|
1976 |
Pfeiffer DR, Hutson SM, Kauffman RF, Lardy HA. Some effects of ionophore A23187 on energy utilization and the distribution of cations and anions in mitochondria. Biochemistry. 15: 2690-7. PMID 820370 DOI: 10.1021/Bi00657A032 |
0.3 |
|
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