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Gaelen T. Hess, Ph.D. - Publications

Affiliations: 
2012 Biophysics Harvard University, Cambridge, MA, United States 
Area:
General Biophysics, Molecular Biology
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19 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Tsedev U, Lin CW, Hess GT, Sarkaria JN, Lam FC, Belcher AM. Phage Particles of Controlled Length and Genome for Targeted Glioblastoma Imaging and Therapeutic Delivery. Acs Nano. PMID 35830573 DOI: 10.1021/acsnano.1c08720  0.556
2020 Ferraro NM, Strober BJ, Einson J, Abell NS, Aguet F, Barbeira AN, Brandt M, Bucan M, Castel SE, Davis JR, Greenwald E, Hess GT, Hilliard AT, Kember RL, Kotis B, et al. Transcriptomic signatures across human tissues identify functional rare genetic variation. Science (New York, N.Y.). 369. PMID 32913073 DOI: 10.1126/Science.Aaz5900  0.328
2019 Morgens DW, Chan C, Kane AJ, Weir NR, Li A, Dubreuil MM, Tsui CK, Hess GT, Lavertu A, Han K, Polyakov N, Zhou J, Handy EL, Alabi P, Dombroski A, et al. Retro-2 protects cells from ricin toxicity by inhibiting ASNA1-mediated ER targeting and insertion of tail-anchored proteins. Elife. 8. PMID 31674906 DOI: 10.7554/Elife.48434  0.389
2019 Tycko J, Wainberg M, Marinov GK, Ursu O, Hess GT, Ego BK, Aradhana, Li A, Truong A, Trevino AE, Spees K, Yao D, Kaplow IM, Greenside PG, Morgens DW, et al. Mitigation of off-target toxicity in CRISPR-Cas9 screens for essential non-coding elements. Nature Communications. 10: 4063. PMID 31492858 DOI: 10.1038/S41467-019-11955-7  0.371
2019 Ritchie C, Cordova AF, Hess GT, Bassik MC, Li L. SLC19A1 Is an Importer of the Immunotransmitter cGAMP. Molecular Cell. PMID 31126740 DOI: 10.1016/J.Molcel.2019.05.006  0.344
2019 Morgens DW, Chan C, Kane AJ, Weir NR, Li A, Dubreuil MM, Tsui CK, Hess GT, Lavertu A, Han K, Polyakov N, Zhou J, Handy EL, Alabi P, Dombroski A, et al. Author response: Retro-2 protects cells from ricin toxicity by inhibiting ASNA1-mediated ER targeting and insertion of tail-anchored proteins Elife. DOI: 10.7554/Elife.48434.022  0.331
2018 Breslow DK, Hoogendoorn S, Kopp AR, Morgens DW, Vu BK, Kennedy MC, Han K, Li A, Hess GT, Bassik MC, Chen JK, Nachury MV. A CRISPR-based screen for Hedgehog signaling provides insights into ciliary function and ciliopathies. Nature Genetics. PMID 29459677 DOI: 10.1038/S41588-018-0054-7  0.32
2017 Li X, Kim Y, Tsang EK, Davis JR, Damani FN, Chiang C, Hess GT, Zappala Z, Strober BJ, Scott AJ, Li A, Ganna A, Bassik MC, Merker JD, et al. The impact of rare variation on gene expression across tissues. Nature. 550: 239-243. PMID 29022581 DOI: 10.1038/Nature24267  0.314
2017 Hess GT, Tycko J, Yao D, Bassik MC. Methods and Applications of CRISPR-Mediated Base Editing in Eukaryotic Genomes. Molecular Cell. 68: 26-43. PMID 28985508 DOI: 10.1016/J.Molcel.2017.09.029  0.373
2017 Phanstiel DH, Van Bortle K, Spacek D, Hess GT, Shamim MS, Machol I, Love MI, Aiden EL, Bassik MC, Snyder MP. Static and Dynamic DNA Loops form AP-1-Bound Activation Hubs during Macrophage Development. Molecular Cell. PMID 28890333 DOI: 10.1016/J.Molcel.2017.08.006  0.301
2017 Morgens DW, Wainberg M, Boyle EA, Ursu O, Araya CL, Tsui CK, Haney MS, Hess GT, Han K, Jeng EE, Li A, Snyder MP, Greenleaf WJ, Kundaje A, Bassik MC. Genome-scale measurement of off-target activity using Cas9 toxicity in high-throughput screens. Nature Communications. 8: 15178. PMID 28474669 DOI: 10.1038/Ncomms15178  0.394
2017 Pala M, Zappala Z, Marongiu M, Li X, Davis JR, Cusano R, Crobu F, Kukurba KR, Gloudemans MJ, Reinier F, Berutti R, Piras MG, Mulas A, Zoledziewska M, Marongiu M, ... ... Hess GT, et al. Population- and individual-specific regulatory variation in Sardinia. Nature Genetics. PMID 28394350 DOI: 10.1038/Ng.3840  0.302
2017 Han K, Jeng EE, Hess GT, Morgens DW, Li A, Bassik MC. Synergistic drug combinations for cancer identified in a CRISPR screen for pairwise genetic interactions. Nature Biotechnology. PMID 28319085 DOI: 10.1038/Nbt.3834  0.337
2017 Han K, Jeng E, Hess G, Morgens D, Li A, Bassik M. Abstract PR04: A CRISPR-based genetic interaction map identifies synergistic drug combinations for cancer Molecular Cancer Therapeutics. 16. DOI: 10.1158/1538-8514.Synthleth-Pr04  0.336
2016 Hess GT, Frésard L, Han K, Lee CH, Li A, Cimprich KA, Montgomery SB, Bassik MC. Directed evolution using dCas9-targeted somatic hypermutation in mammalian cells. Nature Methods. PMID 27798611 DOI: 10.1038/Nmeth.4038  0.41
2016 Arribere JA, Cenik ES, Jain N, Hess GT, Lee CH, Bassik MC, Fire AZ. Translation readthrough mitigation. Nature. PMID 27281202 DOI: 10.1038/Nature18308  0.325
2013 Hess GT, Guimaraes CP, Spooner E, Ploegh HL, Belcher AM. Orthogonal labeling of M13 minor capsid proteins with DNA to self-assemble end-to-end multiphage structures. Acs Synthetic Biology. 2: 490-6. PMID 23713956 DOI: 10.1021/Sb400019S  0.538
2012 Hess GT, Cragnolini JJ, Popp MW, Allen MA, Dougan SK, Spooner E, Ploegh HL, Belcher AM, Guimaraes CP. M13 bacteriophage display framework that allows sortase-mediated modification of surface-accessible phage proteins. Bioconjugate Chemistry. 23: 1478-87. PMID 22759232 DOI: 10.1021/Bc300130Z  0.561
2007 Hess GT, Humphries WH, Fay NC, Payne CK. Cellular binding, motion, and internalization of synthetic gene delivery polymers. Biochimica Et Biophysica Acta. 1773: 1583-8. PMID 17888530 DOI: 10.1016/J.Bbamcr.2007.07.009  0.314
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