R John Solaro - Publications

Affiliations: 
Physiology and Biophysics University of Illinois at Chicago, Chicago, IL, United States 
Area:
Biochemistry, Molecular Biology

43 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2015 Warren CM, Karam CN, Wolska BM, Kobayashi T, de Tombe PP, Arteaga GM, Bos JM, Ackerman MJ, Solaro RJ. A Green Tea Catechin Normalizes the Enhanced Ca2+ Sensitivity of Myofilaments Regulated by a Hypertrophic Cardiomyopathy Associated Mutation in Human Cardiac Troponin I (K206I). Circulation. Cardiovascular Genetics. PMID 26553696 DOI: 10.1161/CIRCGENETICS.115.001234  0.36
2015 Davis RT, Simon JN, Utter M, Mungai P, Alvarez MG, Chowdhury SA, Heydemann A, Ke Y, Wolska BM, Solaro RJ. Knockout of p21-activated kinase-1 attenuates exercise-induced cardiac remodelling through altered calcineurin signalling. Cardiovascular Research. 108: 335-47. PMID 26464331 DOI: 10.1093/cvr/cvv234  0.36
2015 Tarigopula M, Davis RT, Mungai PT, Ryba DM, Wieczorek DF, Cowan CL, Violin JD, Wolska BM, Solaro RJ. Cardiac myosin light chain phosphorylation and inotropic effects of a biased ligand, TRV120023, in a dilated cardiomyopathy model. Cardiovascular Research. 107: 226-34. PMID 26045475 DOI: 10.1093/cvr/cvv162  0.36
2015 Rosas PC, Liu Y, Abdalla MI, Thomas CM, Kidwell DT, Dusio GF, Mukhopadhyay D, Kumar R, Baker KM, Mitchell BM, Powers PA, Fitzsimons DP, Patel BG, Warren CM, Solaro RJ, et al. Phosphorylation of cardiac Myosin-binding protein-C is a critical mediator of diastolic function. Circulation. Heart Failure. 8: 582-94. PMID 25740839 DOI: 10.1161/CIRCHEARTFAILURE.114.001550  0.36
2015 Carley AN, Taglieri DM, Bi J, Solaro RJ, Lewandowski ED. Metabolic efficiency promotes protection from pressure overload in hearts expressing slow skeletal troponin I. Circulation. Heart Failure. 8: 119-27. PMID 25424393 DOI: 10.1161/CIRCHEARTFAILURE.114.001496  0.36
2014 Cheng Y, Lindert S, Kekenes-Huskey P, Rao VS, Solaro RJ, Rosevear PR, Amaro R, McCulloch AD, McCammon JA, Regnier M. Computational studies of the effect of the S23D/S24D troponin I mutation on cardiac troponin structural dynamics. Biophysical Journal. 107: 1675-85. PMID 25296321 DOI: 10.1016/j.bpj.2014.08.008  0.36
2014 Wang Y, Tsui H, Ke Y, Shi Y, Li Y, Davies L, Cartwright EJ, Venetucci L, Zhang H, Terrar DA, Huang CL, Solaro RJ, Wang X, Lei M. Pak1 is required to maintain ventricular Ca²⁺ homeostasis and electrophysiological stability through SERCA2a regulation in mice. Circulation. Arrhythmia and Electrophysiology. 7: 938-48. PMID 25217043 DOI: 10.1161/CIRCEP.113.001198  0.36
2014 Briston SJ, Dibb KM, Solaro RJ, Eisner DA, Trafford AW. Balanced changes in Ca buffering by SERCA and troponin contribute to Ca handling during β-adrenergic stimulation in cardiac myocytes. Cardiovascular Research. 104: 347-54. PMID 25183792 DOI: 10.1093/cvr/cvu201  0.36
2014 Koshman YE, Chu M, Kim T, Kalmanson O, Farjah M, Kumar M, Lewis W, Geenen DL, de Tombe P, Goldspink PH, Solaro RJ, Samarel AM. Cardiomyocyte-specific expression of CRNK, the C-terminal domain of PYK2, maintains ventricular function and slows ventricular remodeling in a mouse model of dilated cardiomyopathy. Journal of Molecular and Cellular Cardiology. 72: 281-91. PMID 24713463 DOI: 10.1016/j.yjmcc.2014.03.021  0.36
2014 Alegre-Cebollada J, Kosuri P, Giganti D, Eckels E, Rivas-Pardo JA, Hamdani N, Warren CM, Solaro RJ, Linke WA, Fernández JM. S-glutathionylation of cryptic cysteines enhances titin elasticity by blocking protein folding. Cell. 156: 1235-46. PMID 24630725 DOI: 10.1016/j.cell.2014.01.056  0.36
2014 Alves ML, Dias FA, Gaffin RD, Simon JN, Montminy EM, Biesiadecki BJ, Hinken AC, Warren CM, Utter MS, Davis RT, Sadayappan S, Robbins J, Wieczorek DF, Solaro RJ, Wolska BM. Desensitization of myofilaments to Ca2+ as a therapeutic target for hypertrophic cardiomyopathy with mutations in thin filament proteins. Circulation. Cardiovascular Genetics. 7: 132-43. PMID 24585742 DOI: 10.1161/CIRCGENETICS.113.000324  0.36
2014 Yar S, Monasky MM, Solaro RJ. Maladaptive modifications in myofilament proteins and triggers in the progression to heart failure and sudden death. PflüGers Archiv : European Journal of Physiology. 466: 1189-97. PMID 24488009 DOI: 10.1007/s00424-014-1457-7  0.76
2014 Puglisi JL, Goldspink PH, Gomes AV, Utter MS, Bers DM, Solaro RJ. Influence of a constitutive increase in myofilament Ca(2+)-sensitivity on Ca(2+)-fluxes and contraction of mouse heart ventricular myocytes. Archives of Biochemistry and Biophysics. 552: 50-9. PMID 24480308 DOI: 10.1016/j.abb.2014.01.019  0.36
2014 Kotlo K, Xing Y, Lather S, Grillon JM, Johnson K, Skidgel RA, Solaro RJ, Danziger RS. PR65A phosphorylation regulates PP2A complex signaling. Plos One. 9: e85000. PMID 24465463 DOI: 10.1371/journal.pone.0085000  0.36
2013 Patel BG, Wilder T, Solaro RJ. Novel control of cardiac myofilament response to calcium by S-glutathionylation at specific sites of myosin binding protein C. Frontiers in Physiology. 4: 336. PMID 24312057 DOI: 10.3389/fphys.2013.00336  0.36
2013 Monasky MM, Taglieri DM, Henze M, Warren CM, Utter MS, Soergel DG, Violin JD, Solaro RJ. The β-arrestin-biased ligand TRV120023 inhibits angiotensin II-induced cardiac hypertrophy while preserving enhanced myofilament response to calcium. American Journal of Physiology. Heart and Circulatory Physiology. 305: H856-66. PMID 23873795 DOI: 10.1152/ajpheart.00327.2013  0.76
2013 Yar S, Chowdhury SA, Davis RT, Kobayashi M, Monasky MM, Rajan S, Wolska BM, Gaponenko V, Kobayashi T, Wieczorek DF, Solaro RJ. Conserved Asp-137 is important for both structure and regulatory functions of cardiac α-tropomyosin (α-TM) in a novel transgenic mouse model expressing α-TM-D137L. The Journal of Biological Chemistry. 288: 16235-46. PMID 23609439 DOI: 10.1074/jbc.M113.458695  0.36
2013 Jeong EM, Monasky MM, Gu L, Taglieri DM, Patel BG, Liu H, Wang Q, Greener I, Dudley SC, Solaro RJ. Tetrahydrobiopterin improves diastolic dysfunction by reversing changes in myofilament properties. Journal of Molecular and Cellular Cardiology. 56: 44-54. PMID 23247392 DOI: 10.1016/j.yjmcc.2012.12.003  0.36
2013 Monasky MM, Taglieri DM, Jacobson AK, Haizlip KM, Solaro RJ, Janssen PM. Post-translational modifications of myofilament proteins involved in length-dependent prolongation of relaxation in rabbit right ventricular myocardium. Archives of Biochemistry and Biophysics. 535: 22-9. PMID 23085150 DOI: 10.1016/j.abb.2012.10.005  0.76
2013 Henze M, Patrick SE, Hinken A, Scruggs SB, Goldspink P, de Tombe PP, Kobayashi M, Ping P, Kobayashi T, Solaro RJ. New insights into the functional significance of the acidic region of the unique N-terminal extension of cardiac troponin I. Biochimica Et Biophysica Acta. 1833: 823-32. PMID 22940544 DOI: 10.1016/j.bbamcr.2012.08.012  0.36
2012 Schulz EM, Correll RN, Sheikh HN, Lofrano-Alves MS, Engel PL, Newman G, Schultz JEJ, Molkentin JD, Wolska BM, Solaro RJ, Wieczorek DF. Tropomyosin dephosphorylation results in compensated cardiac hypertrophy Journal of Biological Chemistry. 287: 44478-44489. PMID 23148217 DOI: 10.1074/jbc.M112.402040  0.36
2012 Hinken AC, Hanft LM, Scruggs SB, Sadayappan S, Robbins J, Solaro RJ, McDonald KS. Protein kinase C depresses cardiac myocyte power output and attenuates myofilament responses induced by protein kinase A. Journal of Muscle Research and Cell Motility. 33: 439-48. PMID 22527640 DOI: 10.1007/s10974-012-9294-9  0.4
2012 Nixon BR, Thawornkaiwong A, Jin J, Brundage EA, Little SC, Davis JP, Solaro RJ, Biesiadecki BJ. AMP-activated protein kinase phosphorylates cardiac troponin I at Ser-150 to increase myofilament calcium sensitivity and blunt PKA-dependent function. The Journal of Biological Chemistry. 287: 19136-47. PMID 22493448 DOI: 10.1074/jbc.M111.323048  0.36
2012 Lovelock JD, Monasky MM, Jeong EM, Lardin HA, Liu H, Patel BG, Taglieri DM, Gu L, Kumar P, Pokhrel N, Zeng D, Belardinelli L, Sorescu D, Solaro RJ, Dudley SC. Ranolazine improves cardiac diastolic dysfunction through modulation of myofilament calcium sensitivity. Circulation Research. 110: 841-50. PMID 22343711 DOI: 10.1161/CIRCRESAHA.111.258251  0.36
2012 Avner BS, Shioura KM, Scruggs SB, Grachoff M, Geenen DL, Helseth DL, Farjah M, Goldspink PH, Solaro RJ. Myocardial infarction in mice alters sarcomeric function via post-translational protein modification. Molecular and Cellular Biochemistry. 363: 203-15. PMID 22160857 DOI: 10.1007/s11010-011-1172-z  0.4
2012 Monasky MM, Taglieri DM, Patel BG, Chernoff J, Wolska BM, Ke Y, Solaro RJ. p21-activated kinase improves cardiac contractility during ischemia-reperfusion concomitant with changes in troponin-T and myosin light chain 2 phosphorylation. American Journal of Physiology. Heart and Circulatory Physiology. 302: H224-30. PMID 22037191 DOI: 10.1152/ajpheart.00612.2011  0.76
2011 Liu W, Zi M, Naumann R, Ulm S, Jin J, Taglieri DM, Prehar S, Gui J, Tsui H, Xiao RP, Neyses L, Solaro RJ, Ke Y, Cartwright EJ, Lei M, et al. Pak1 as a novel therapeutic target for antihypertrophic treatment in the heart. Circulation. 124: 2702-15. PMID 22082674 DOI: 10.1161/CIRCULATIONAHA.111.048785  0.36
2011 Taglieri DM, Monasky MM, Knezevic I, Sheehan KA, Lei M, Wang X, Chernoff J, Wolska BM, Ke Y, Solaro RJ. Ablation of p21-activated kinase-1 in mice promotes isoproterenol-induced cardiac hypertrophy in association with activation of Erk1/2 and inhibition of protein phosphatase 2A. Journal of Molecular and Cellular Cardiology. 51: 988-96. PMID 21971074 DOI: 10.1016/j.yjmcc.2011.09.016  0.76
2011 Egom EE, Mohamed TM, Mamas MA, Shi Y, Liu W, Chirico D, Stringer SE, Ke Y, Shaheen M, Wang T, Chacko S, Wang X, Solaro RJ, Fath-Ordoubadi F, Cartwright EJ, et al. Activation of Pak1/Akt/eNOS signaling following sphingosine-1-phosphate release as part of a mechanism protecting cardiomyocytes against ischemic cell injury. American Journal of Physiology. Heart and Circulatory Physiology. 301: H1487-95. PMID 21705677 DOI: 10.1152/ajpheart.01003.2010  0.36
2011 Karam CN, Warren CM, Rajan S, de Tombe PP, Wieczorek DF, Solaro RJ. Expression of tropomyosin-κ induces dilated cardiomyopathy and depresses cardiac myofilament tension by mechanisms involving cross-bridge dependent activation and altered tropomyosin phosphorylation. Journal of Muscle Research and Cell Motility. 31: 315-22. PMID 21221740 DOI: 10.1007/s10974-010-9237-2  0.36
2011 Sheehan KA, Arteaga GM, Hinken AC, Dias FA, Ribeiro C, Wieczorek DF, Solaro RJ, Wolska BM. Functional effects of a tropomyosin mutation linked to FHC contribute to maladaptation during acidosis. Journal of Molecular and Cellular Cardiology. 50: 442-50. PMID 21047515 DOI: 10.1016/j.yjmcc.2010.10.032  0.4
2010 Force T, Bonow RO, Houser SR, Solaro RJ, Hershberger RE, Adhikari B, Anderson ME, Boineau R, Byrne BJ, Cappola TP, Kalluri R, LeWinter MM, Maron MS, Molkentin JD, Ommen SR, et al. Research priorities in hypertrophic cardiomyopathy: report of a Working Group of the National Heart, Lung, and Blood Institute. Circulation. 122: 1130-3. PMID 20837938 DOI: 10.1161/CIRCULATIONAHA.110.950089  0.36
2010 Avner BS, Hinken AC, Yuan C, Solaro RJ. H2O2 alters rat cardiac sarcomere function and protein phosphorylation through redox signaling. American Journal of Physiology. Heart and Circulatory Physiology. 299: H723-30. PMID 20562337 DOI: 10.1152/ajpheart.00050.2010  0.4
2010 Scruggs SB, Reisdorph R, Armstrong ML, Warren CM, Reisdorph N, Solaro RJ, Buttrick PM. A novel, in-solution separation of endogenous cardiac sarcomeric proteins and identification of distinct charged variants of regulatory light chain. Molecular & Cellular Proteomics : McP. 9: 1804-18. PMID 20445002 DOI: 10.1074/mcp.M110.000075  0.36
2010 Biesiadecki BJ, Tachampa K, Yuan C, Jin JP, de Tombe PP, Solaro RJ. Removal of the cardiac troponin I N-terminal extension improves cardiac function in aged mice. The Journal of Biological Chemistry. 285: 19688-98. PMID 20410305 DOI: 10.1074/jbc.M109.086892  0.4
2010 Lu QW, Hinken AC, Patrick SE, Solaro RJ, Kobayashi T. Phosphorylation of cardiac troponin I at protein kinase C site threonine 144 depresses cooperative activation of thin filaments. The Journal of Biological Chemistry. 285: 11810-7. PMID 20164197 DOI: 10.1074/jbc.M109.055657  0.4
2010 Rajan S, Jagatheesan G, Karam CN, Alves ML, Bodi I, Schwartz A, Bulcao CF, D'Souza KM, Akhter SA, Boivin GP, Dube DK, Petrashevskaya N, Herr AB, Hullin R, Liggett SB, ... ... Solaro RJ, et al. Molecular and functional characterization of a novel cardiac-specific human tropomyosin isoform. Circulation. 121: 410-8. PMID 20065163 DOI: 10.1161/CIRCULATIONAHA.109.889725  0.36
2009 Jagatheesan G, Rajan S, Schulz EM, Ahmed RP, Petrashevskaya N, Schwartz A, Boivin GP, Arteaga GM, Wang T, Wang YG, Ashraf M, Liggett SB, Lorenz J, Solaro RJ, Wieczorek DF. An internal domain of beta-tropomyosin increases myofilament Ca(2+) sensitivity. American Journal of Physiology. Heart and Circulatory Physiology. 297: H181-90. PMID 19429821 DOI: 10.1152/ajpheart.00329.2008  0.36
2009 Scruggs SB, Hinken AC, Thawornkaiwong A, Robbins J, Walker LA, de Tombe PP, Geenen DL, Buttrick PM, Solaro RJ. Ablation of ventricular myosin regulatory light chain phosphorylation in mice causes cardiac dysfunction in situ and affects neighboring myofilament protein phosphorylation. The Journal of Biological Chemistry. 284: 5097-106. PMID 19106098 DOI: 10.1074/jbc.M807414200  0.4
2008 Yuan C, Solaro RJ. Myofilament proteins: From cardiac disorders to proteomic changes. Proteomics. Clinical Applications. 2: 788-99. PMID 21136879 DOI: 10.1002/prca.200780076  0.4
2008 Yuan C, Sheng Q, Tang H, Li Y, Zeng R, Solaro RJ. Quantitative comparison of sarcomeric phosphoproteomes of neonatal and adult rat hearts. American Journal of Physiology. Heart and Circulatory Physiology. 295: H647-56. PMID 18552161 DOI: 10.1152/ajpheart.00357.2008  0.4
2008 Sumandea MP, Rybin VO, Hinken AC, Wang C, Kobayashi T, Harleton E, Sievert G, Balke CW, Feinmark SJ, Solaro RJ, Steinberg SF. Tyrosine phosphorylation modifies protein kinase C δ-dependent phosphorylation of cardiac troponin I Journal of Biological Chemistry. 283: 22680-22689. PMID 18550549 DOI: 10.1074/jbc.M802396200  0.36
2007 Howarth JW, Meller J, Solaro RJ, Trewhella J, Rosevear PR. Phosphorylation-dependent conformational transition of the cardiac specific N-extension of troponin I in cardiac troponin. Journal of Molecular Biology. 373: 706-22. PMID 17854829 DOI: 10.1016/j.jmb.2007.08.035  0.36
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