R John Solaro - Publications

Affiliations: 
Physiology and Biophysics University of Illinois at Chicago, Chicago, IL, United States 
Area:
Biochemistry, Molecular Biology

250 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Lertwanakarn T, Suntravat M, Sanchez EE, Boonhoh W, Solaro RJ, Wolska BM, Martin JL, de Tombe PP, Tachampa K. Suppression of cardiomyocyte functions by β-CTX isolated from the Thai king cobra () venom via an alternative method. The Journal of Venomous Animals and Toxins Including Tropical Diseases. 26: e20200005. PMID 32742278 DOI: 10.1590/1678-9199-JVATITD-2020-0005  0.48
2020 Lertwanakarn T, Suntravat M, Sanchez EE, Wolska BM, Solaro RJ, de Tombe P, Tachampa K. Beta-cardiotoxin, a novel compound from king cobra venom, suppresses cardiac function via non-beta-adrenergic pathway. Toxicon : Official Journal of the International Society On Toxinology. 177: S58. PMID 32635097 DOI: 10.1016/j.toxicon.2019.12.133  0.48
2020 Chowdhury SAK, Warren CM, Simon JN, Ryba DM, Batra A, Varga P, Kranias EG, Tardiff JC, Solaro RJ, Wolska BM. Modifications of Sarcoplasmic Reticulum Function Prevent Progression of Sarcomere-Linked Hypertrophic Cardiomyopathy Despite a Persistent Increase in Myofilament Calcium Response. Frontiers in Physiology. 11: 107. PMID 32210830 DOI: 10.3389/fphys.2020.00107  0.48
2019 Moss RL, de Tombe PP, Solaro RJ. Toward an understanding of the regulation of myofibrillar function. The Journal of General Physiology. 151: 1-2. PMID 30578329 DOI: 10.1085/jgp.201812288  0.32
2017 Nagalingam RS, Sundaresan NR, Gupta MP, Geenen DL, Solaro RJ, Gupta M. A cardiac-enriched microRNA, miR-378, blocks cardiac hypertrophy by targeting Ras signaling. The Journal of Biological Chemistry. 292: 5123. PMID 28341711 DOI: 10.1074/jbc.A112.442384  0.32
2016 Li KL, Ghashghaee NB, Solaro RJ, Dong W. Sarcomere length dependent effects on the interaction between cTnC and cTnI in skinned papillary muscle strips. Archives of Biochemistry and Biophysics. PMID 26944554 DOI: 10.1016/j.abb.2016.02.030  0.56
2016 Solaro RJ. Why we need to understand the mechanics of developing cardiac sarcomeres in humans. The Journal of Physiology. 594: 255. PMID 26767884 DOI: 10.1113/JP271706  0.56
2015 Huang CL, Solaro RJ, Ke Y, Lei M. Editorial: Ca(2+) Signaling and Heart Rhythm. Frontiers in Physiology. 6: 423. PMID 26793124 DOI: 10.3389/fphys.2015.00423  0.56
2015 Warren CM, Karam CN, Wolska BM, Kobayashi T, de Tombe PP, Arteaga GM, Bos JM, Ackerman MJ, Solaro RJ. A Green Tea Catechin Normalizes the Enhanced Ca2+ Sensitivity of Myofilaments Regulated by a Hypertrophic Cardiomyopathy Associated Mutation in Human Cardiac Troponin I (K206I). Circulation. Cardiovascular Genetics. PMID 26553696 DOI: 10.1161/CIRCGENETICS.115.001234  0.56
2015 Davis RT, Simon JN, Utter M, Mungai P, Alvarez MG, Chowdhury SA, Heydemann A, Ke Y, Wolska BM, Solaro RJ. Knockout of p21-activated kinase-1 attenuates exercise-induced cardiac remodelling through altered calcineurin signalling. Cardiovascular Research. 108: 335-47. PMID 26464331 DOI: 10.1093/cvr/cvv234  0.56
2015 Wilder T, Ryba DM, Wieczorek DF, Wolska BM, Solaro RJ. N-acetylcysteine reverses diastolic dysfunction and hypertrophy in familial hypertrophic cardiomyopathy. American Journal of Physiology. Heart and Circulatory Physiology. 309: H1720-30. PMID 26432840 DOI: 10.1152/ajpheart.00339.2015  0.48
2015 Solaro RJ. A sarcomeric protein tongue-twister: post-translation, citrullination/deimination and elimination of arginine residues. Cardiovascular Research. 108: 212-4. PMID 26392345 DOI: 10.1093/cvr/cvv220  0.56
2015 Utter MS, Ryba DM, Li BH, Wolska BM, Solaro RJ. Omecamtiv mecarbil, a cardiac myosin activator, increases Ca2+-sensitivity in myofilaments with a dilated cardiomyopathy mutant tropomyosin E54K. Journal of Cardiovascular Pharmacology. PMID 26065842 DOI: 10.1097/FJC.0000000000000286  0.56
2015 Tarigopula M, Davis RT, Mungai PT, Ryba DM, Wieczorek DF, Cowan CL, Violin JD, Wolska BM, Solaro RJ. Cardiac myosin light chain phosphorylation and inotropic effects of a biased ligand, TRV120023, in a dilated cardiomyopathy model. Cardiovascular Research. 107: 226-34. PMID 26045475 DOI: 10.1093/cvr/cvv162  0.56
2015 Rosas PC, Liu Y, Abdalla MI, Thomas CM, Kidwell DT, Dusio GF, Mukhopadhyay D, Kumar R, Baker KM, Mitchell BM, Powers PA, Fitzsimons DP, Patel BG, Warren CM, Solaro RJ, et al. Phosphorylation of cardiac Myosin-binding protein-C is a critical mediator of diastolic function. Circulation. Heart Failure. 8: 582-94. PMID 25740839 DOI: 10.1161/CIRCHEARTFAILURE.114.001550  0.56
2015 Lei M, Wang X, Ke Y, Solaro RJ. Regulation of Ca(2+) transient by PP2A in normal and failing heart. Frontiers in Physiology. 6: 13. PMID 25688213 DOI: 10.3389/fphys.2015.00013  0.56
2015 Carley AN, Taglieri DM, Bi J, Solaro RJ, Lewandowski ED. Metabolic efficiency promotes protection from pressure overload in hearts expressing slow skeletal troponin I. Circulation. Heart Failure. 8: 119-27. PMID 25424393 DOI: 10.1161/CIRCHEARTFAILURE.114.001496  0.36
2014 Ke Y, Wang X, Jin XY, Solaro RJ, Lei M. PAK1 is a novel cardiac protective signaling molecule. Frontiers of Medicine. 8: 399-403. PMID 25416031 DOI: 10.1007/s11684-014-0380-9  0.56
2014 Simon JN, Chowdhury SA, Warren CM, Sadayappan S, Wieczorek DF, Solaro RJ, Wolska BM. Ceramide-mediated depression in cardiomyocyte contractility through PKC activation and modulation of myofilament protein phosphorylation. Basic Research in Cardiology. 109: 445. PMID 25280528 DOI: 10.1007/s00395-014-0445-6  0.56
2014 Wang Y, Tsui H, Ke Y, Shi Y, Li Y, Davies L, Cartwright EJ, Venetucci L, Zhang H, Terrar DA, Huang CL, Solaro RJ, Wang X, Lei M. Pak1 is required to maintain ventricular Ca²⁺ homeostasis and electrophysiological stability through SERCA2a regulation in mice. Circulation. Arrhythmia and Electrophysiology. 7: 938-48. PMID 25217043 DOI: 10.1161/CIRCEP.113.001198  0.56
2014 Briston SJ, Dibb KM, Solaro RJ, Eisner DA, Trafford AW. Balanced changes in Ca buffering by SERCA and troponin contribute to Ca handling during β-adrenergic stimulation in cardiac myocytes. Cardiovascular Research. 104: 347-54. PMID 25183792 DOI: 10.1093/cvr/cvu201  0.56
2014 Li KL, Rieck D, Solaro RJ, Dong W. In situ time-resolved FRET reveals effects of sarcomere length on cardiac thin-filament activation. Biophysical Journal. 107: 682-93. PMID 25099807 DOI: 10.1016/j.bpj.2014.05.044  0.56
2014 Burniston JG, Gramolini AO, Solaro RJ. Cardiac proteomics. Biomed Research International. 2014: 903538. PMID 25025073 DOI: 10.1155/2014/903538  0.56
2014 Koshman YE, Chu M, Kim T, Kalmanson O, Farjah M, Kumar M, Lewis W, Geenen DL, de Tombe P, Goldspink PH, Solaro RJ, Samarel AM. Cardiomyocyte-specific expression of CRNK, the C-terminal domain of PYK2, maintains ventricular function and slows ventricular remodeling in a mouse model of dilated cardiomyopathy. Journal of Molecular and Cellular Cardiology. 72: 281-91. PMID 24713463 DOI: 10.1016/j.yjmcc.2014.03.021  0.56
2014 Alegre-Cebollada J, Kosuri P, Giganti D, Eckels E, Rivas-Pardo JA, Hamdani N, Warren CM, Solaro RJ, Linke WA, Fernández JM. S-glutathionylation of cryptic cysteines enhances titin elasticity by blocking protein folding. Cell. 156: 1235-46. PMID 24630725 DOI: 10.1016/j.cell.2014.01.056  0.56
2014 Alves ML, Dias FA, Gaffin RD, Simon JN, Montminy EM, Biesiadecki BJ, Hinken AC, Warren CM, Utter MS, Davis RT, Sadayappan S, Robbins J, Wieczorek DF, Solaro RJ, Wolska BM. Desensitization of myofilaments to Ca2+ as a therapeutic target for hypertrophic cardiomyopathy with mutations in thin filament proteins. Circulation. Cardiovascular Genetics. 7: 132-43. PMID 24585742 DOI: 10.1161/CIRCGENETICS.113.000324  0.56
2014 Yar S, Monasky MM, Solaro RJ. Maladaptive modifications in myofilament proteins and triggers in the progression to heart failure and sudden death. PflüGers Archiv : European Journal of Physiology. 466: 1189-97. PMID 24488009 DOI: 10.1007/s00424-014-1457-7  0.56
2014 Puglisi JL, Goldspink PH, Gomes AV, Utter MS, Bers DM, Solaro RJ. Influence of a constitutive increase in myofilament Ca(2+)-sensitivity on Ca(2+)-fluxes and contraction of mouse heart ventricular myocytes. Archives of Biochemistry and Biophysics. 552: 50-9. PMID 24480308 DOI: 10.1016/j.abb.2014.01.019  0.56
2014 Kotlo K, Xing Y, Lather S, Grillon JM, Johnson K, Skidgel RA, Solaro RJ, Danziger RS. PR65A phosphorylation regulates PP2A complex signaling. Plos One. 9: e85000. PMID 24465463 DOI: 10.1371/journal.pone.0085000  0.56
2013 Schulz EM, Wilder T, Chowdhury SA, Sheikh HN, Wolska BM, Solaro RJ, Wieczorek DF. Decreasing tropomyosin phosphorylation rescues tropomyosin-induced familial hypertrophic cardiomyopathy. The Journal of Biological Chemistry. 288: 28925-35. PMID 23960072 DOI: 10.1074/jbc.M113.466466  0.56
2013 Rieck DC, Li KL, Ouyang Y, Solaro RJ, Dong WJ. Structural basis for the in situ Ca(2+) sensitization of cardiac troponin C by positive feedback from force-generating myosin cross-bridges. Archives of Biochemistry and Biophysics. 537: 198-209. PMID 23896515 DOI: 10.1016/j.abb.2013.07.013  0.56
2013 Monasky MM, Taglieri DM, Henze M, Warren CM, Utter MS, Soergel DG, Violin JD, Solaro RJ. The β-arrestin-biased ligand TRV120023 inhibits angiotensin II-induced cardiac hypertrophy while preserving enhanced myofilament response to calcium. American Journal of Physiology. Heart and Circulatory Physiology. 305: H856-66. PMID 23873795 DOI: 10.1152/ajpheart.00327.2013  0.76
2013 Yar S, Chowdhury SA, Davis RT, Kobayashi M, Monasky MM, Rajan S, Wolska BM, Gaponenko V, Kobayashi T, Wieczorek DF, Solaro RJ. Conserved Asp-137 is important for both structure and regulatory functions of cardiac α-tropomyosin (α-TM) in a novel transgenic mouse model expressing α-TM-D137L. The Journal of Biological Chemistry. 288: 16235-46. PMID 23609439 DOI: 10.1074/jbc.M113.458695  0.56
2013 Nagalingam RS, Sundaresan NR, Gupta MP, Geenen DL, Solaro RJ, Gupta M. A cardiac-enriched microRNA, miR-378, blocks cardiac hypertrophy by targeting Ras signaling. The Journal of Biological Chemistry. 288: 11216-32. PMID 23447532 DOI: 10.1074/jbc.M112.442384  0.32
2013 Solaro RJ, Henze M, Kobayashi T. Integration of troponin I phosphorylation with cardiac regulatory networks. Circulation Research. 112: 355-66. PMID 23329791 DOI: 10.1161/CIRCRESAHA.112.268672  0.56
2013 Jeong EM, Monasky MM, Gu L, Taglieri DM, Patel BG, Liu H, Wang Q, Greener I, Dudley SC, Solaro RJ. Tetrahydrobiopterin improves diastolic dysfunction by reversing changes in myofilament properties. Journal of Molecular and Cellular Cardiology. 56: 44-54. PMID 23247392 DOI: 10.1016/j.yjmcc.2012.12.003  0.56
2013 Monasky MM, Taglieri DM, Jacobson AK, Haizlip KM, Solaro RJ, Janssen PM. Post-translational modifications of myofilament proteins involved in length-dependent prolongation of relaxation in rabbit right ventricular myocardium. Archives of Biochemistry and Biophysics. 535: 22-9. PMID 23085150 DOI: 10.1016/j.abb.2012.10.005  0.56
2013 Henze M, Patrick SE, Hinken A, Scruggs SB, Goldspink P, de Tombe PP, Kobayashi M, Ping P, Kobayashi T, Solaro RJ. New insights into the functional significance of the acidic region of the unique N-terminal extension of cardiac troponin I. Biochimica Et Biophysica Acta. 1833: 823-32. PMID 22940544 DOI: 10.1016/j.bbamcr.2012.08.012  0.56
2012 Schulz EM, Correll RN, Sheikh HN, Lofrano-Alves MS, Engel PL, Newman G, Schultz JEJ, Molkentin JD, Wolska BM, Solaro RJ, Wieczorek DF. Tropomyosin dephosphorylation results in compensated cardiac hypertrophy Journal of Biological Chemistry. 287: 44478-44489. PMID 23148217 DOI: 10.1074/jbc.M112.402040  0.56
2012 Lai HL, Grachoff M, McGinley AL, Khan FF, Warren CM, Chowdhury SA, Wolska BM, Solaro RJ, Geenen DL, Wang QT. Maintenance of adult cardiac function requires the chromatin factor Asxl2. Journal of Molecular and Cellular Cardiology. 53: 734-41. PMID 23046516 DOI: 10.1016/j.yjmcc.2012.08.014  0.56
2012 Solaro RJ, Rao MC. Kate Bárány: a life of science, teaching, and service. Journal of Muscle Research and Cell Motility. 33: 369-71. PMID 22614738 DOI: 10.1007/s10974-012-9301-1  0.56
2012 Hinken AC, Hanft LM, Scruggs SB, Sadayappan S, Robbins J, Solaro RJ, McDonald KS. Protein kinase C depresses cardiac myocyte power output and attenuates myofilament responses induced by protein kinase A. Journal of Muscle Research and Cell Motility. 33: 439-48. PMID 22527640 DOI: 10.1007/s10974-012-9294-9  0.56
2012 Nixon BR, Thawornkaiwong A, Jin J, Brundage EA, Little SC, Davis JP, Solaro RJ, Biesiadecki BJ. AMP-activated protein kinase phosphorylates cardiac troponin I at Ser-150 to increase myofilament calcium sensitivity and blunt PKA-dependent function. The Journal of Biological Chemistry. 287: 19136-47. PMID 22493448 DOI: 10.1074/jbc.M111.323048  0.56
2012 Knezevic I, Patel A, Sundaresan NR, Gupta MP, Solaro RJ, Nagalingam RS, Gupta M. A novel cardiomyocyte-enriched microRNA, miR-378, targets insulin-like growth factor 1 receptor: implications in postnatal cardiac remodeling and cell survival. The Journal of Biological Chemistry. 287: 12913-26. PMID 22367207 DOI: 10.1074/jbc.M111.331751  0.56
2012 Lovelock JD, Monasky MM, Jeong EM, Lardin HA, Liu H, Patel BG, Taglieri DM, Gu L, Kumar P, Pokhrel N, Zeng D, Belardinelli L, Sorescu D, Solaro RJ, Dudley SC. Ranolazine improves cardiac diastolic dysfunction through modulation of myofilament calcium sensitivity. Circulation Research. 110: 841-50. PMID 22343711 DOI: 10.1161/CIRCRESAHA.111.258251  0.56
2012 Avner BS, Shioura KM, Scruggs SB, Grachoff M, Geenen DL, Helseth DL, Farjah M, Goldspink PH, Solaro RJ. Myocardial infarction in mice alters sarcomeric function via post-translational protein modification. Molecular and Cellular Biochemistry. 363: 203-15. PMID 22160857 DOI: 10.1007/s11010-011-1172-z  0.56
2012 Monasky MM, Taglieri DM, Patel BG, Chernoff J, Wolska BM, Ke Y, Solaro RJ. p21-activated kinase improves cardiac contractility during ischemia-reperfusion concomitant with changes in troponin-T and myosin light chain 2 phosphorylation. American Journal of Physiology. Heart and Circulatory Physiology. 302: H224-30. PMID 22037191 DOI: 10.1152/ajpheart.00612.2011  0.56
2012 Solaro RJ, Leinwand LA. Role of sarcomeres in cellular tension, shortening, and signaling in cardiac muscle Muscle. 1: 161-172. DOI: 10.1016/B978-0-12-381510-1.00013-2  0.56
2011 Liu W, Zi M, Naumann R, Ulm S, Jin J, Taglieri DM, Prehar S, Gui J, Tsui H, Xiao RP, Neyses L, Solaro RJ, Ke Y, Cartwright EJ, Lei M, et al. Pak1 as a novel therapeutic target for antihypertrophic treatment in the heart. Circulation. 124: 2702-15. PMID 22082674 DOI: 10.1161/CIRCULATIONAHA.111.048785  0.56
2011 Taglieri DM, Monasky MM, Knezevic I, Sheehan KA, Lei M, Wang X, Chernoff J, Wolska BM, Ke Y, Solaro RJ. Ablation of p21-activated kinase-1 in mice promotes isoproterenol-induced cardiac hypertrophy in association with activation of Erk1/2 and inhibition of protein phosphatase 2A. Journal of Molecular and Cellular Cardiology. 51: 988-96. PMID 21971074 DOI: 10.1016/j.yjmcc.2011.09.016  0.56
2011 Belin RJ, Sumandea MP, Sievert GA, Harvey LA, Geenen DL, Solaro RJ, de Tombe PP. Interventricular differences in myofilament function in experimental congestive heart failure. PflüGers Archiv : European Journal of Physiology. 462: 795-809. PMID 21927813 DOI: 10.1007/s00424-011-1024-4  0.56
2011 Ai X, Jiang A, Ke Y, Solaro RJ, Pogwizd SM. Enhanced activation of p21-activated kinase 1 in heart failure contributes to dephosphorylation of connexin 43. Cardiovascular Research. 92: 106-14. PMID 21727092 DOI: 10.1093/cvr/cvr163  0.56
2011 Egom EE, Mohamed TM, Mamas MA, Shi Y, Liu W, Chirico D, Stringer SE, Ke Y, Shaheen M, Wang T, Chacko S, Wang X, Solaro RJ, Fath-Ordoubadi F, Cartwright EJ, et al. Activation of Pak1/Akt/eNOS signaling following sphingosine-1-phosphate release as part of a mechanism protecting cardiomyocytes against ischemic cell injury. American Journal of Physiology. Heart and Circulatory Physiology. 301: H1487-95. PMID 21705677 DOI: 10.1152/ajpheart.01003.2010  0.56
2011 Pound KM, Arteaga GM, Fasano M, Wilder T, Fischer SK, Warren CM, Wende AR, Farjah M, Abel ED, Solaro RJ, Lewandowski ED. Expression of slow skeletal TnI in adult mouse hearts confers metabolic protection to ischemia. Journal of Molecular and Cellular Cardiology. 51: 236-43. PMID 21640727 DOI: 10.1016/j.yjmcc.2011.05.014  0.56
2011 Scruggs SB, Solaro RJ. The significance of regulatory light chain phosphorylation in cardiac physiology. Archives of Biochemistry and Biophysics. 510: 129-34. PMID 21345328 DOI: 10.1016/j.abb.2011.02.013  0.56
2011 Solaro RJ, Kobayashi T. Protein phosphorylation and signal transduction in cardiac thin filaments. The Journal of Biological Chemistry. 286: 9935-40. PMID 21257760 DOI: 10.1074/jbc.R110.197731  0.56
2011 Solaro RJ, Stull JT. Thematic minireview series on signaling in cardiac sarcomeres in health and disease. The Journal of Biological Chemistry. 286: 9895. PMID 21257756 DOI: 10.1074/jbc.R110.214403  0.56
2011 Karam CN, Warren CM, Rajan S, de Tombe PP, Wieczorek DF, Solaro RJ. Expression of tropomyosin-κ induces dilated cardiomyopathy and depresses cardiac myofilament tension by mechanisms involving cross-bridge dependent activation and altered tropomyosin phosphorylation. Journal of Muscle Research and Cell Motility. 31: 315-22. PMID 21221740 DOI: 10.1007/s10974-010-9237-2  0.56
2011 Shioura KM, Farjah M, Geenen DL, Solaro RJ, Goldspink PH. Myofilament calcium sensitization delays decompensated hypertrophy differently between the sexes following myocardial infarction. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 300: R361-8. PMID 21106909 DOI: 10.1152/ajpregu.00321.2010  0.56
2011 Sheehan KA, Arteaga GM, Hinken AC, Dias FA, Ribeiro C, Wieczorek DF, Solaro RJ, Wolska BM. Functional effects of a tropomyosin mutation linked to FHC contribute to maladaptation during acidosis. Journal of Molecular and Cellular Cardiology. 50: 442-50. PMID 21047515 DOI: 10.1016/j.yjmcc.2010.10.032  0.56
2010 Peña JR, Szkudlarek AC, Warren CM, Heinrich LS, Gaffin RD, Jagatheesan G, del Monte F, Hajjar RJ, Goldspink PH, Solaro RJ, Wieczorek DF, Wolska BM. Neonatal gene transfer of Serca2a delays onset of hypertrophic remodeling and improves function in familial hypertrophic cardiomyopathy. Journal of Molecular and Cellular Cardiology. 49: 993-1002. PMID 20854827 DOI: 10.1016/j.yjmcc.2010.09.010  0.56
2010 Force T, Bonow RO, Houser SR, Solaro RJ, Hershberger RE, Adhikari B, Anderson ME, Boineau R, Byrne BJ, Cappola TP, Kalluri R, LeWinter MM, Maron MS, Molkentin JD, Ommen SR, et al. Research priorities in hypertrophic cardiomyopathy: report of a Working Group of the National Heart, Lung, and Blood Institute. Circulation. 122: 1130-3. PMID 20837938 DOI: 10.1161/CIRCULATIONAHA.110.950089  0.56
2010 Solaro RJ, Sheehan KA, Lei M, Ke Y. The curious role of sarcomeric proteins in control of diverse processes in cardiac myocytes. The Journal of General Physiology. 136: 13-9. PMID 20584888 DOI: 10.1085/jgp.201010462  0.56
2010 Avner BS, Hinken AC, Yuan C, Solaro RJ. H2O2 alters rat cardiac sarcomere function and protein phosphorylation through redox signaling. American Journal of Physiology. Heart and Circulatory Physiology. 299: H723-30. PMID 20562337 DOI: 10.1152/ajpheart.00050.2010  0.56
2010 Solaro RJ, Warren CM, Scruggs SB. Why is it important to analyze the cardiac sarcomere subproteome? Expert Review of Proteomics. 7: 311-4. PMID 20536300 DOI: 10.1586/epr.10.15  0.56
2010 Solaro RJ. Sarcomere control mechanisms and the dynamics of the cardiac cycle. Journal of Biomedicine & Biotechnology. 2010: 105648. PMID 20467475 DOI: 10.1155/2010/105648  0.56
2010 Scruggs SB, Reisdorph R, Armstrong ML, Warren CM, Reisdorph N, Solaro RJ, Buttrick PM. A novel, in-solution separation of endogenous cardiac sarcomeric proteins and identification of distinct charged variants of regulatory light chain. Molecular & Cellular Proteomics : McP. 9: 1804-18. PMID 20445002 DOI: 10.1074/mcp.M110.000075  0.56
2010 Biesiadecki BJ, Tachampa K, Yuan C, Jin JP, de Tombe PP, Solaro RJ. Removal of the cardiac troponin I N-terminal extension improves cardiac function in aged mice. The Journal of Biological Chemistry. 285: 19688-98. PMID 20410305 DOI: 10.1074/jbc.M109.086892  0.56
2010 Warren CM, Geenen DL, Helseth DL, Xu H, Solaro RJ. Sub-proteomic fractionation, iTRAQ, and OFFGEL-LC-MS/MS approaches to cardiac proteomics. Journal of Proteomics. 73: 1551-61. PMID 20394843 DOI: 10.1016/j.jprot.2010.03.016  0.56
2010 Solaro RJ, van der Velden J. Why does troponin I have so many phosphorylation sites? Fact and fancy. Journal of Molecular and Cellular Cardiology. 48: 810-6. PMID 20188739 DOI: 10.1016/j.yjmcc.2010.02.014  0.56
2010 Lu QW, Hinken AC, Patrick SE, Solaro RJ, Kobayashi T. Phosphorylation of cardiac troponin I at protein kinase C site threonine 144 depresses cooperative activation of thin filaments. The Journal of Biological Chemistry. 285: 11810-7. PMID 20164197 DOI: 10.1074/jbc.M109.055657  0.56
2010 Ke Y, Sheehan KA, Egom EE, Lei M, Solaro RJ. Novel bradykinin signaling in adult rat cardiac myocytes through activation of p21-activated kinase. American Journal of Physiology. Heart and Circulatory Physiology. 298: H1283-9. PMID 20154261 DOI: 10.1152/ajpheart.01070.2009  0.56
2010 Solaro RJ. The activity of cardiac myocytes reflects a confluence of a multitude of electrical and chemical signals that promote and control the ability of the myocytes to shorten and develop force. Journal of Molecular and Cellular Cardiology. 48: 809. PMID 20152840 DOI: 10.1016/j.yjmcc.2010.02.006  0.56
2010 Egom EE, Ke Y, Solaro RJ, Lei M. Cardioprotection in ischemia/reperfusion injury: spotlight on sphingosine-1-phosphate and bradykinin signalling. Progress in Biophysics and Molecular Biology. 103: 142-7. PMID 20080123 DOI: 10.1016/j.pbiomolbio.2010.01.001  0.56
2010 Rajan S, Jagatheesan G, Karam CN, Alves ML, Bodi I, Schwartz A, Bulcao CF, D'Souza KM, Akhter SA, Boivin GP, Dube DK, Petrashevskaya N, Herr AB, Hullin R, Liggett SB, ... ... Solaro RJ, et al. Molecular and functional characterization of a novel cardiac-specific human tropomyosin isoform. Circulation. 121: 410-8. PMID 20065163 DOI: 10.1161/CIRCULATIONAHA.109.889725  0.56
2010 Solaro RJ, de Tombe PP. Reply to Smith letter: Controversy persists after over 100 years of the Frank-Starling mechanism Journal of Molecular and Cellular Cardiology. 49: 709. DOI: 10.1016/j.yjmcc.2010.07.004  0.56
2009 Kirk JA, MacGowan GA, Evans C, Smith SH, Warren CM, Mamidi R, Chandra M, Stewart AF, Solaro RJ, Shroff SG. Left ventricular and myocardial function in mice expressing constitutively pseudophosphorylated cardiac troponin I. Circulation Research. 105: 1232-9. PMID 19850940 DOI: 10.1161/CIRCRESAHA.109.205427  0.56
2009 Jagatheesan G, Rajan S, Schulz EM, Ahmed RP, Petrashevskaya N, Schwartz A, Boivin GP, Arteaga GM, Wang T, Wang YG, Ashraf M, Liggett SB, Lorenz J, Solaro RJ, Wieczorek DF. An internal domain of beta-tropomyosin increases myofilament Ca(2+) sensitivity. American Journal of Physiology. Heart and Circulatory Physiology. 297: H181-90. PMID 19429821 DOI: 10.1152/ajpheart.00329.2008  0.56
2009 Engel PL, Hinken A, Solaro RJ. Differential effects of phosphorylation of regions of troponin I in modifying cooperative activation of cardiac thin filaments. Journal of Molecular and Cellular Cardiology. 47: 359-64. PMID 19426736 DOI: 10.1016/j.yjmcc.2009.04.016  0.56
2009 Solaro RJ. CK-1827452, a sarcomere-directed cardiac myosin activator for acute and chronic heart disease. Idrugs : the Investigational Drugs Journal. 12: 243-51. PMID 19350469  0.56
2009 Warren CM, Kobayashi T, Solaro RJ. Sites of intra- and intermolecular cross-linking of the N-terminal extension of troponin I in human cardiac whole troponin complex. The Journal of Biological Chemistry. 284: 14258-66. PMID 19321456 DOI: 10.1074/jbc.M807621200  0.56
2009 Hartman TJ, Martin JL, Solaro RJ, Samarel AM, Russell B. CapZ dynamics are altered by endothelin-1 and phenylephrine via PIP2- and PKC-dependent mechanisms. American Journal of Physiology. Cell Physiology. 296: C1034-9. PMID 19295171 DOI: 10.1152/ajpcell.00544.2008  0.56
2009 Abraham SJ, Kobayashi T, Solaro RJ, Gaponenko V. Differences in lysine pKa values may be used to improve NMR signal dispersion in reductively methylated proteins. Journal of Biomolecular Nmr. 43: 239-46. PMID 19280122 DOI: 10.1007/s10858-009-9306-2  0.56
2009 Solaro RJ. Maintaining cooperation among cardiac myofilament proteins through thick and thin. The Journal of Physiology. 587: 3. PMID 19119179 DOI: 10.1113/jphysiol.2008.166751  0.56
2009 Scruggs SB, Hinken AC, Thawornkaiwong A, Robbins J, Walker LA, de Tombe PP, Geenen DL, Buttrick PM, Solaro RJ. Ablation of ventricular myosin regulatory light chain phosphorylation in mice causes cardiac dysfunction in situ and affects neighboring myofilament protein phosphorylation. The Journal of Biological Chemistry. 284: 5097-106. PMID 19106098 DOI: 10.1074/jbc.M807414200  0.56
2009 Sheehan KA, Ke Y, Wolska BM, Solaro RJ. Expression of active p21-activated kinase-1 induces Ca2+ flux modification with altered regulatory protein phosphorylation in cardiac myocytes. American Journal of Physiology. Cell Physiology. 296: C47-58. PMID 18923061 DOI: 10.1152/ajpcell.00012.2008  0.56
2008 Yuan C, Solaro RJ. Myofilament proteins: From cardiac disorders to proteomic changes. Proteomics. Clinical Applications. 2: 788-99. PMID 21136879 DOI: 10.1002/prca.200780076  0.56
2008 Ke Y, Lei M, Solaro RJ. Regulation of cardiac excitation and contraction by p21 activated kinase-1. Progress in Biophysics and Molecular Biology. 98: 238-50. PMID 19351515 DOI: 10.1016/j.pbiomolbio.2009.01.007  0.56
2008 Solaro RJ. Multiplex kinase signaling modifies cardiac function at the level of sarcomeric proteins. The Journal of Biological Chemistry. 283: 26829-33. PMID 18567577 DOI: 10.1074/jbc.R800037200  0.56
2008 Yuan C, Sheng Q, Tang H, Li Y, Zeng R, Solaro RJ. Quantitative comparison of sarcomeric phosphoproteomes of neonatal and adult rat hearts. American Journal of Physiology. Heart and Circulatory Physiology. 295: H647-56. PMID 18552161 DOI: 10.1152/ajpheart.00357.2008  0.36
2008 Sumandea MP, Rybin VO, Hinken AC, Wang C, Kobayashi T, Harleton E, Sievert G, Balke CW, Feinmark SJ, Solaro RJ, Steinberg SF. Tyrosine phosphorylation modifies protein kinase C δ-dependent phosphorylation of cardiac troponin I Journal of Biological Chemistry. 283: 22680-22689. PMID 18550549 DOI: 10.1074/jbc.M802396200  0.56
2008 Minami H, Wolska BM, Stojanovic MO, Solaro RJ. Reversal of effects of acidosis on contraction of rat heart myocytes by CGP-48506. Frontiers in Bioscience : a Journal and Virtual Library. 13: 5638-45. PMID 18508612 DOI: 10.2741/3106  0.56
2008 Tachampa K, Kobayashi T, Wang H, Martin AF, Biesiadecki BJ, Solaro RJ, de Tombe PP. Increased cross-bridge cycling kinetics after exchange of C-terminal truncated troponin I in skinned rat cardiac muscle. The Journal of Biological Chemistry. 283: 15114-21. PMID 18378675 DOI: 10.1074/jbc.M801636200  0.56
2008 Solaro RJ, de Tombe PP. Review focus series: sarcomeric proteins as key elements in integrated control of cardiac function. Cardiovascular Research. 77: 616-8. PMID 18192242 DOI: 10.1093/cvr/cvn004  0.56
2008 Solaro RJ, Rosevear P, Kobayashi T. The unique functions of cardiac troponin I in the control of cardiac muscle contraction and relaxation. Biochemical and Biophysical Research Communications. 369: 82-7. PMID 18162178 DOI: 10.1016/j.bbrc.2007.12.114  0.56
2008 Warren CM, Arteaga GM, Rajan S, Ahmed RP, Wieczorek DF, Solaro RJ. Use of 2-D DIGE analysis reveals altered phosphorylation in a tropomyosin mutant (Glu54Lys) linked to dilated cardiomyopathy. Proteomics. 8: 100-5. PMID 18095372 DOI: 10.1002/pmic.200700772  0.56
2007 Lei M, Ke Y, Solaro RJ. Pak1: steps towards understanding the regulatory mechanisms of pacemaker function of the heart. Future Cardiology. 3: 473-6. PMID 19804297 DOI: 10.2217/14796678.3.5.473  0.56
2007 Nowak G, Peña JR, Urboniene D, Geenen DL, Solaro RJ, Wolska BM. Correlations between alterations in length-dependent Ca2+ activation of cardiac myofilaments and the end-systolic pressure-volume relation. Journal of Muscle Research and Cell Motility. 28: 415-9. PMID 18365757 DOI: 10.1007/s10974-008-9136-y  0.48
2007 Howarth JW, Meller J, Solaro RJ, Trewhella J, Rosevear PR. Phosphorylation-dependent conformational transition of the cardiac specific N-extension of troponin I in cardiac troponin. Journal of Molecular Biology. 373: 706-22. PMID 17854829 DOI: 10.1016/j.jmb.2007.08.035  0.56
2007 Solaro RJ. Mechanisms of the Frank-Starling law of the heart: the beat goes on. Biophysical Journal. 93: 4095-6. PMID 17766360 DOI: 10.1529/biophysj.107.117200  0.56
2007 Wu SC, Solaro RJ. Protein kinase C zeta. A novel regulator of both phosphorylation and de-phosphorylation of cardiac sarcomeric proteins. The Journal of Biological Chemistry. 282: 30691-8. PMID 17724026 DOI: 10.1074/jbc.M703670200  0.56
2007 Solaro RJ. Translational medicine with a capital T, troponin T, that is Circulation Research. 101: 114-115. PMID 17641232 DOI: 10.1161/CIRCRESAHA.107.157420  0.56
2007 Ke Y, Lum H, Solaro RJ. Inhibition of endothelial barrier dysfunction by P21-activated kinase-1. Canadian Journal of Physiology and Pharmacology. 85: 281-8. PMID 17612635 DOI: 10.1139/y06-100  0.56
2007 Sheehan KA, Ke Y, Solaro RJ. p21-Activated kinase-1 and its role in integrated regulation of cardiac contractility American Journal of Physiology - Regulatory Integrative and Comparative Physiology. 293. PMID 17609315 DOI: 10.1152/ajpregu.00253.2007  0.56
2007 Hinken AC, Solaro RJ. A dominant role of cardiac molecular motors in the intrinsic regulation of ventricular ejection and relaxation. Physiology (Bethesda, Md.). 22: 73-80. PMID 17420299 DOI: 10.1152/physiol.00043.2006  0.56
2007 Solaro RJ. Nitroxyl effects on myocardium provide new insights into the significance of altered myofilament response to calcium in the regulation of contractility Journal of Physiology. 580: 697. PMID 17347260 DOI: 10.1113/jphysiol.2007.131649  0.56
2007 Bupha-Intr T, Wattanapermpool J, Peña JR, Wolska BM, Solaro RJ. Myofilament response to Ca2+ and Na+/H+ exchanger activity in sex hormone-related protection of cardiac myocytes from deactivation in hypercapnic acidosis American Journal of Physiology - Regulatory Integrative and Comparative Physiology. 292. PMID 17038443 DOI: 10.1152/ajpregu.00376.2006  0.56
2007 Solaro RJ, Arteaga GM. Heart failure, ischemia/reperfusion injury and cardiac troponin Advances in Experimental Medicine and Biology. 592: 191-200. DOI: 10.1007/978-4-431-38453-3_17  0.56
2006 Biesiadecki BJ, Solaro RJ. When hearts fail so does skeletal muscle: breaking a vicious cycle. Circulation Research. 98: 1456-8. PMID 16794192 DOI: 10.1161/01.RES.0000231259.29646.74  0.56
2006 Kobayashi T, Solaro RJ. Increased Ca2+ affinity of cardiac thin filaments reconstituted with cardiomyopathy-related mutant cardiac troponin I Journal of Biological Chemistry. 281: 13471-13477. PMID 16531415 DOI: 10.1074/jbc.M509561200  0.56
2006 Kass DA, Solaro RJ. Mechanisms and use of calcium-sensitizing agents in the failing heart Circulation. 113: 305-315. PMID 16418450 DOI: 10.1161/CIRCULATIONAHA.105.542407  0.56
2005 Vahebi S, Solaro RJ. Cardiac sarcomeric function, small G-protein signaling, and heart failure Panminerva Medica. 47: 133-142. PMID 16462722  0.56
2005 Solaro RJ. Remote control of A-band cardiac thin filaments by the I-Z-I protein network of cardiac sarcomeres Trends in Cardiovascular Medicine. 15: 148-152. PMID 16099379 DOI: 10.1016/j.tcm.2005.04.007  0.56
2005 Arteaga GM, Warren CM, Milutinovic S, Martin AF, Solaro RJ. Specific enhancement of sarcomeric response to Ca2+ protects murine myocardium against ischemia-reperfusion dysfunction American Journal of Physiology - Heart and Circulatory Physiology. 289. PMID 16024565 DOI: 10.1152/ajpheart.00520.2005  0.56
2005 Layland J, Solaro RJ, Shah AM. Regulation of cardiac contractile function by troponin I phosphorylation Cardiovascular Research. 66: 12-21. PMID 15769444 DOI: 10.1016/j.cardiores.2004.12.022  0.56
2005 Kobayashi T, Solaro RJ. Calcium, thin filaments, and the integrative biology of cardiac contractility Annual Review of Physiology. 67: 39-67. PMID 15709952 DOI: 10.1146/annurev.physiol.67.040403.114025  0.56
2004 Parmacek MS, Solaro RJ. Biology of the troponin complex in cardiac myocytes. Progress in Cardiovascular Diseases. 47: 159-76. PMID 15736582 DOI: 10.1016/j.pcad.2004.07.003  0.56
2004 Sorsa T, Pollesello P, Solaro RJ. The contractile apparatus as a target for drugs against heart failure: Interaction of levosimendan, a calcium sensitiser, with cardiac troponin c Molecular and Cellular Biochemistry. 266: 87-107. PMID 15646030 DOI: 10.1023/B:MCBI.0000049141.37823.19  0.56
2004 Towbin JA, Solaro RJ. Genetics of dilated cardiomyopathy: More genes that kill Journal of the American College of Cardiology. 44: 2041-2043. PMID 15542289 DOI: 10.1016/j.jacc.2004.08.028  0.56
2004 Kobayashi T, Dong WJ, Burkart EM, Cheung HC, Solaro RJ. Effects of protein kinase C dependent phosphorylation and a familial hypertrophic cardiomyopathy-related mutation of cardiac troponin I on structural transition of troponin C and myofilament activation. Biochemistry. 43: 5996-6004. PMID 15147183 DOI: 10.1021/bi036073n  0.56
2004 Solaro RJ. The special structure and function of troponin I in regulation of cardiac contraction and relaxation Advances in Experimental Medicine and Biology. 538: 389-402. PMID 15098685  0.56
2004 Pyle WG, Solaro RJ. At the Crossroads of Myocardial Signaling: The Role of Z-Discs in Intracellular Signaling and Cardiac Function Circulation Research. 94: 296-305. PMID 14976140 DOI: 10.1161/01.RES.0000116143.74830.A9  0.56
2002 Solaro RJ, Varghese J, Marian AJ, Chandra M. Molecular mechanisms of cardiac myofilament activation: modulation by pH and a troponin T mutant R92Q. Basic Research in Cardiology. 97: I102-10. PMID 12479243  0.56
2002 Arteaga GM, Kobayashi T, Solaro RJ. Molecular actions of drugs that sensitize cardiac myofilaments to Ca2+ Annals of Medicine. 34: 248-258. PMID 12371709 DOI: 10.1080/078538902320322510  0.56
2002 Pyle WG, Sumandea MP, Solaro RJ, De Tombe PP. Troponin I serines 43/45 and regulation of cardiac myofilament function. American Journal of Physiology. Heart and Circulatory Physiology. 283: H1215-24. PMID 12181153 DOI: 10.1152/ajpheart.00128.2002  0.56
2002 Martin AF, Phillips RM, Kumar A, Crawford K, Abbas Z, Lessard JL, de Tombe P, Solaro RJ. Ca(2+) activation and tension cost in myofilaments from mouse hearts ectopically expressing enteric gamma-actin. American Journal of Physiology. Heart and Circulatory Physiology. 283: H642-9. PMID 12124211 DOI: 10.1152/ajpheart.00890.2001  0.48
2001 Montgomery DE, Chandra M, Huang QQ, Jin JP, Solaro RJ. Transgenic incorporation of skeletal TnT into cardiac myofilaments blunts PKC-mediated depression of force American Journal of Physiology - Heart and Circulatory Physiology. 280: H1011-H1018. PMID 11179042  0.56
2001 Chandra M, Rundell VLM, Tardiff JC, Leinwand LA, De Tombe PP, Solaro RJ. Ca2+ activation of myofilaments from transgenic mouse hearts expressing R92Q mutant cardiac troponin t American Journal of Physiology - Heart and Circulatory Physiology. 280: H705-H713. PMID 11158969  0.56
2000 De Tombe PP, Solaro RJ. Integration of cardiac myofilament activity and regulation with pathways signaling hypertrophy and failure Annals of Biomedical Engineering. 28: 991-1001. PMID 11144684 DOI: 10.1114/1.1312189  0.56
2000 Solaro RJ. Myosin light chain phosphatase: A cinderella of cellular signaling Circulation Research. 87: 173-175. PMID 10926864  0.56
2000 Arteaga GM, Palmiter KA, Leiden JM, Solaro RJ. Attenuation of length dependence of calcium activation in myofilaments of transgenic mouse hearts expressing slow skeletal troponin I. The Journal of Physiology. 526: 541-9. PMID 10922006  0.56
1999 Meehan J, Piano MR, Solaro RJ, Kennedy JM. Heavy long-term ethanol consumption induces an alpha- to beta-myosin heavy chain isoform transition in rat Basic Research in Cardiology. 94: 481-488. PMID 10651160 DOI: 10.1007/s003950050164  0.56
1999 Solaro RJ. Integration of myofilament response to Ca2+ with cardiac pump regulation and pump dynamics American Journal of Physiology. 277. PMID 10644243  0.56
1999 Solaro RJ. Is calcium the 'cure' for dilated cardiomyopathy? Nature Medicine. 5: 1353-1354. PMID 10581071 DOI: 10.1038/70916  0.56
1999 Schwertz DW, Vizgirda V, Solaro RJ, Piano MR, Ryjewski C. Sexual dimorphism in rat left atrial function and response to adrenergic stimulation Molecular and Cellular Biochemistry. 200: 143-153. PMID 10569194 DOI: 10.1023/A:1007011807383  0.56
1999 Chandra M, Kim JJ, Solaro RJ. An improved method for exchanging troponin subunits in detergent skinned rat cardiac fiber bundles Biochemical and Biophysical Research Communications. 263: 219-223. PMID 10486280 DOI: 10.1006/bbrc.1999.1341  0.56
1999 Chandra M, Montgomery DE, Kim JJ, Solaro RJ. The N-terminal region of troponin T is essential for the maximal activation of rat cardiac myofilaments Journal of Molecular and Cellular Cardiology. 31: 867-880. PMID 10329214 DOI: 10.1006/jmcc.1999.0928  0.56
1999 Rarick HM, Tang Hp, Guo XD, Martin AF, Solaro RJ. Interactions at the NH2-terminal interface of cardiac troponin I modulate myofilament activation Journal of Molecular and Cellular Cardiology. 31: 363-375. PMID 10093049 DOI: 10.1006/jmcc.1998.0870  0.56
1999 Piano MR, Rosenblum C, Solaro RJ, Schwertz D. Calcium sensitivity and the effect of the calcium sensitizing drug pimobendan in the alcoholic isolated rat atrium Journal of Cardiovascular Pharmacology. 33: 237-242. PMID 10028931 DOI: 10.1097/00005344-199902000-00009  0.56
1999 Solaro RJ. Troponin I, stunning, hypertrophy, and failure of the heart Circulation Research. 84: 122-124. PMID 9915781  0.56
1998 Powers FM, Fogelson B, Sturgeon C, Solaro RJ, Law WR. Depressed myofilament co-operativity associated with post-cardioplegic myocardial depression Journal of Molecular and Cellular Cardiology. 30: 1779-1787. PMID 9769234 DOI: 10.1006/jmcc.1998.0742  0.56
1998 Solaro RJ, Rarick HM. Troponin and tropomyosin: Proteins that switch on and tune in the activity of cardiac myofilaments Circulation Research. 83: 471-480. PMID 9734469  0.56
1998 Rethinasamy P, Muthuchamy M, Hewett T, Boivin G, Wolska BM, Evans C, Solaro RJ, Wieczorek DF. Molecular and physiological effects of α-tropomyosin ablation in the mouse Circulation Research. 82: 116-123. PMID 9440710 DOI: 10.1161/01.RES.82.1.116  0.56
1997 Fraker LD, Eyk VJ, Solaro RJ. Reversal of phosphate induced decreases in force by the benzimidazole pyridazinone, UD-CG 212 CL, in myofilaments from human ventricle Molecular and Cellular Biochemistry. 176: 83-88. PMID 9406148 DOI: 10.1023/A:1006827012495  0.56
1997 Chandra M, Dong WJ, Pan BS, Cheung HC, Solaro RJ. Effects of protein kinase A phosphorylation on signaling between cardiac troponin I and the N-terminal domain of cardiac troponin C. Biochemistry. 36: 13305-11. PMID 9341222 DOI: 10.1021/bi9710129  0.56
1997 Rarick HM, Tu XH, Solaro RJ, Martin AF. The C terminus of cardiac troponin I is essential for full inhibitory activity and Ca2+ sensitivity of rat myofibrils Journal of Biological Chemistry. 272: 26887-26892. PMID 9341121 DOI: 10.1074/jbc.272.43.26887  0.56
1997 Palmiter KA, Solaro RJ. Molecular mechanisms regulating the myofilament response to Ca2+: Implications of mutations causal for familial hypertrophic cardiomyopathy Basic Research in Cardiology, Supplement. 92: 63-74. PMID 9202846  0.56
1997 Dong WJ, Chandra M, Xing J, Solaro RJ, Cheung HC. Conformation of the N-terminal segment of a monocysteine mutant of troponin I from cardiac muscle. Biochemistry. 36: 6745-53. PMID 9184156 DOI: 10.1021/bi962226d  0.56
1997 Fogelson BG, Powers FM, Sturgeon C, Solaro RJ, Law WR. Cellular basis for post-cardioplegic cardiac dysfunction Faseb Journal. 11.  0.56
1996 Wernberg G, Gentry JM, Solaro RJ. Association of Chairmen of Departments of Physiology 1995 survey results The Physiologist.. 39: 83-89. PMID 16764117  0.56
1996 Powers FM, Palmiter KA, Solaro RJ. E-1020, a water soluble imidazopyridine, has direct effects on Ca2+-dependent force and ATP hydrolysis of canine and bovine cardiac myofilaments Molecular and Cellular Biochemistry. 160: 33-39. PMID 8901452  0.56
1996 Rarick HM, Opgenorth TJ, Von Geldern TW, Wu-Wong JR, Solaro RJ. An essential myosin light chain peptide induces supramaximal stimulation of cardiac myofibrillar ATPase activity Journal of Biological Chemistry. 271: 27039-27043. PMID 8900193 DOI: 10.1074/jbc.271.43.27039  0.56
1996 Babu A, Sonnenblick EH, Gulati J, Solaro RJ, Van Eyk J. Altered interactions among thin filament proteins modulate cardiac function: A clarification [1] Journal of Molecular and Cellular Cardiology. 28: 1829-1831. PMID 8877793 DOI: 10.1006/jmcc.1996.0173  0.56
1996 Wolska BM, Stojanovic MO, Luo W, Kranias EG, Solaro RJ. Effect of ablation of phospholamban on dynamics of cardiac myocyte contraction and intracellular Ca2+ American Journal of Physiology - Cell Physiology. 271. PMID 8760070  0.56
1996 Solaro RJ, Van Eyk J. Altered interactions among thin filament proteins modulate cardiac function Journal of Molecular and Cellular Cardiology. 28: 217-230. PMID 8729055 DOI: 10.1006/jmcc.1996.0021  0.56
1996 Palmiter KA, Kitada Y, Muthuchamy M, Wieczorek DF, Solaro RJ. Exchange of β- for α-tropomyosin in hearts of transgenic mice induces changes in thin filament response to Ca2+, strong cross-bridge binding, and protein phosphorylation Journal of Biological Chemistry. 271: 11611-11614. PMID 8662805 DOI: 10.1074/jbc.271.20.11611  0.56
1996 Wolska BM, Solaro RJ. Method for isolation of adult mouse cardiac myocytes for studies of contraction and microfluorimetry American Journal of Physiology - Heart and Circulatory Physiology. 40.  0.56
1995 Wattanapermpool J, Reiser PJ, Solaro RJ. Troponin I isoforms and differential effects of acidic pH on soleus and cardiac myofilaments American Journal of Physiology - Cell Physiology. 268. PMID 7864071  0.56
1995 Powers FM, Solaro RJ. Caffeine alters cardiac myofilament activity and regulation independently of Ca2+ binding to troponin C American Journal of Physiology - Cell Physiology. 268. PMID 7611352  0.56
1995 Kleerekoper Q, Howarth JW, Guo X, Solaro RJ, Rosevear PR. Cardiac troponin I induced conformational changes in cardiac troponin C as monitored by NMR using site-directed spin and isotope labeling Biochemistry. 34: 13343-13352. PMID 7577919 DOI: 10.1021/bi00041a010  0.56
1995 Wattanapermpool J, Guo X, Solaro RJ. The unique amino-terminal peptide of cardiac troponin I regulates myofibrillar activity only when it is phosphorylated Journal of Molecular and Cellular Cardiology. 27: 1383-1391. PMID 7473784 DOI: 10.1006/jmcc.1995.0131  0.56
1994 Guo X, Wattanapermpool J, Palmiter KA, Murphy AM, Solaro RJ. Mutagenesis of Cardiac Troponin I: Role of the Unique NH2-Terminal Peptide in Myofilament Activation Journal of Biological Chemistry. 269: 15210-15216. PMID 8195157  0.56
1994 Averyhart-Fullard V, Fraker LD, Murphy AM, Solaro RJ. Differential Regulation of Slow-skeletal and Cardiac Troponin I mRNA during Development and by Thyroid Hormone in Rat Heart Journal of Molecular and Cellular Cardiology. 26: 609-616. PMID 8072015 DOI: 10.1006/jmcc.1994.1073  0.56
1994 Ball KL, Solaro RJ. Discoordinate Regulation of Contractile Protein Gene Expression in the Senescent Rat Myocardium Journal of Molecular and Cellular Cardiology. 26: 519-525. PMID 8072007 DOI: 10.1006/jmcc.1994.1062  0.56
1994 Ball KL, Johnson MD, Solaro RJ. Isoform specific interactions of troponin I and troponin C determine pH sensitivity of myofibrillar Ca2+ activation Biochemistry. 33: 8464-8471. PMID 8031779  0.56
1994 Reiser PJ, Westfall MV, Schiaffino S, Solaro RJ. Tension production and thin-filament protein isoforms in developing rat myocardium American Journal of Physiology - Heart and Circulatory Physiology. 267. PMID 7943406  0.56
1994 Solaro RJ. Heart failure and the response of cardiac myofilaments to Ca2+ Heart Failure. 10: 150-155.  0.56
1993 Westfall MV, Wahler GM, Solaro RJ. A highly specific benzimidazole pyridazinone reverses phosphate-induced changes in cardiac myofilament activation Biochemistry. 32: 10464-10470. PMID 8399192  0.56
1993 Kawamura A, Wahler GM, Solaro RJ. Rwj-24517, a positive inotropic agent, has novel effects on action potentials in guinea pig myocardium Journal of Cardiovascular Pharmacology. 22: 519-525. PMID 7505352  0.56
1993 Solaro RJ, Powers FM, Gao L, Gwathmey JK. Control of myofilament activation in heart failure Circulation. 87.  0.56
1992 Solaro RJ. Myosin and why hearts fail Circulation. 85: 1945-1947. PMID 1572051  0.56
1992 Westfall MV, Wahler GM, Fujino K, Solaro RJ. Electrophysiological actions of the pimobendan metabolite, UD-CG 212 Cl, in guinea pig myocardium Journal of Pharmacology and Experimental Therapeutics. 260: 58-63. PMID 1346167  0.56
1991 Gwathmey JK, Hajjar RJ, Solaro RJ. Contractile deactivation and uncoupling of crossbridges. Effects of 2,3-butanedione monoxime on mammalian myocardium Circulation Research. 69: 1280-1292. PMID 1934358  0.56
1991 Martin AF, Ball K, Gao L, Kumar P, Solaro RJ. Identification and functional significance of troponin I isoforms in neonatal rat heart myofibrils Circulation Research. 69: 1244-1252. PMID 1934354  0.56
1991 Solaro RJ. Regulation of Ca<sup>2+</sup>-signaling in cardiac myofilaments Medicine and Science in Sports and Exercise. 23: 1145-1148. PMID 1758291  0.56
1990 Murphy AM, Solaro RJ. Developmental difference in the stimulation of cardiac myofibrillar Mg<sup>2+</sup>-ATPase activity by calmidazolium Pediatric Research. 28: 46-47. PMID 2143010  0.56
1990 Dieckman LJ, Solaro RJ. Effect of thyroid status on thin-filament Ca2+ regulation and expression of troponin I in perinatal and adult rat hearts Circulation Research. 67: 344-351. PMID 2142896  0.56
1990 McAuliffe JJ, Gao L, Solaro RJ. Changes in myofibrillar activation and troponin C Ca2+ binding associated with troponin T isoform switching in developing rabbit heart Circulation Research. 66: 1204-1216. PMID 2139820  0.56
1990 Pan BS, Palmiter KA, Plonczynski M, Solaro RJ. Slowly exchanging calcium binding sites unique to cardiac/slow muscle troponin C Journal of Molecular and Cellular Cardiology. 22: 1117-1124. PMID 2095435 DOI: 10.1016/0022-2828(90)90075-D  0.56
1990 Westfall MV, Solaro RJ. Alterations in myofibrillar function and protein profiles after complete global ischemia in rat hearts Circulation Research. 70: 302-313. PMID 1531186  0.56
1989 Herzig JW, Botelho LH, Solaro RJ. Myofibrillar Ca++ activation and heart failure - Ca++ sensitization by the cardiotonic agent APP 201-533 Basic Research in Cardiology. 84: 117-124. PMID 2818453 DOI: 10.1007/BF02650351  0.56
1989 Fujino K, Sperelakis N, Solaro RJ. Direct effects of pimobendan on cardiac myofilaments Progress in Clinical and Biological Research. 315: 602-603. PMID 2798516  0.56
1989 Edes I, Solaro RJ, Kranias EG. Changes in phosphoinositide turnover in isolated guinea pig hearts stimulated with isoproterenol Circulation Research. 65: 989-996. PMID 2551534  0.56
1989 Rapundalo ST, Solaro RJ, Kranias EG. Inotropic responses to isoproterenol and phosphodiesterase inhibitors in intact guinea pig hearts: Comparison of cyclic AMP levels and phosphorylation of sarcoplasmic reticulum and myofibrillar proteins Circulation Research. 64: 104-111. PMID 2535795  0.56
1989 Solaro RJ, El-Salehl SC, Kentish JC. Ca2+, pH and the regulation of cardiac myofilament force and ATPase activity Molecular and Cellular Biochemistry. 89: 163-167. PMID 2530435 DOI: 10.1007/BF00220770  0.56
1989 Solaro RJ, Fujino K, Sperelakis N. The positive inotropic effect of pimobendan involves stereospecific increases in the calcium sensitivity of cardiac myofilaments Journal of Cardiovascular Pharmacology. 14: S7-S12. PMID 2478795  0.56
1989 Just H, Solaro RJ. Introduction Journal of Cardiovascular Pharmacology. 14: v-vii.  0.56
1989 Just H, Solaro RJ. Pharmacotherapy of congestive heart failure Journal of Cardiovascular Pharmacology. 14.  0.56
1988 Jakab G, Rapundalo ST, Solaro RJ, Kranias EG. Phosphorylation of phospholipids in isolated guinea pig hearts stimulated with isoprenaline Biochemical Journal. 251: 189-194. PMID 3390153  0.56
1988 Fujino K, Sperelakis N, Solaro RJ. Differential effects of d- and l-pimobendan on cardiac myofilament calcium sensitivity Journal of Pharmacology and Experimental Therapeutics. 247: 519-523. PMID 3183951  0.56
1988 Solaro RJ, Lee JA, Kentish JC, Allen DG. Effects of acidosis on ventricular muscle from adult and neonatal rats Circulation Research. 63: 779-787. PMID 3168178  0.56
1988 Whitmer JT, Kumar P, Solaro RJ. Calcium transport properties of cardiac sarcoplasmic reticulum from cardiomyopathic Syrian hamsters (BIO 53.58 and 14.6): Evidence for a quantitative defect in dilated myopathic hearts not evident in hypertrophic hearts Circulation Research. 62: 81-85. PMID 2961480  0.56
1988 Garvey JL, Kranias EG, Solaro RJ. Phosphorylation of C-protein, troponin I and phospholamban in isolated rabbit hearts Biochemical Journal. 249: 709-714. PMID 2895634  0.56
1988 Fujino K, Sperelakis N, Solaro RJ. Sensitization of dog and guinea pig heart myofilaments to Ca2+ activation and the inotropic effect of pimobendan: Comparison with milrinone Circulation Research. 63: 911-922. PMID 2846200  0.56
1988 El-Saleh SC, Solaro RJ. Troponin I enhances acidic pH-induced depression of Ca2+ binding to the regulatory sites in skeletal troponin C Journal of Biological Chemistry. 263: 3274-3278. PMID 2830278  0.56
1987 Pan BS, Solaro RJ. Calcium-binding properties of troponin C in detergent-skinned heart muscle fibers Journal of Biological Chemistry. 262: 7839-7849. PMID 3584144  0.56
1987 El-Saleh SC, Solaro RJ. Calmidazolium, a calmodulin antagonist, stimulates calcium-troponin C and calcium-calmodulin-dependent activation of striated muscle myofilaments Journal of Biological Chemistry. 262: 17240-17246. PMID 2960681  0.56
1986 El-Saleh SC, Potter JD, Solaro RJ. Alteration of actin-tropomyosin interaction in 2,4-pentanedione-treated rabbit skeletal myofibrils Journal of Biological Chemistry. 261: 14646-14650. PMID 2945819  0.56
1986 Solaro RJ, Bousquet P, Johnson JD. Stimulation of cardiac myofilament force, ATPase activity and troponin C Ca++ binding by bepridil Journal of Pharmacology and Experimental Therapeutics. 238: 502-507. PMID 2942677  0.56
1986 Solaro RJ, Kumar P, Blanchard EM, Martin AF. Differential effects of pH on calcium activation of myofilaments of adult and perinatal dog hearts. Evidence for developmental differences in thin filament regulation. Circulation Research. 58: 721-9. PMID 2940029  0.56
1986 Rouslin W, Erickson JL, Solaro RJ. Effects of oligomycin and acidosis on rates of ATP depletion in ischemic heart muscle American Journal of Physiology - Heart and Circulatory Physiology. 250. PMID 2937313  0.56
1985 Kranias EG, Garvey JL, Srivastava RD, Solaro RJ. Phosphorylation and functional modifications of sarcoplasmic reticulum and myofibrils in isolated rabbit hearts stimulated with isoprenaline Biochemical Journal. 226: 113-121. PMID 3156585  0.56
1985 Li T, Sperelakis N, Teneick RE, Solaro RJ. Effects of diacetyl monoxime on cardiac excitation-contraction coupling Journal of Pharmacology and Experimental Therapeutics. 232: 688-695. PMID 3156242  0.56
1985 Pan B, Solaro RJ. Effects of sarcomere length on the force-pCa relation and troponin C calcium binding of chemically skinned fibers of canine ventricular muscle Federation Proceedings. 44.  0.56
1985 Godt RE, Fender KJ, Pan BS, Solaro RJ. Myosin light chain phosphorylation hastens relaxation of skinned skeletal muscle fibers Federation Proceedings. 44.  0.56
1984 Shiner JS, Solaro RJ. The hill coefficient for the Ca2+-activation of striated muscle contraction. Biophysical Journal. 46: 541-3. PMID 6498270 DOI: 10.1016/S0006-3495(84)84051-5  0.56
1984 Blanchard EM, Solaro RJ. Inhibition of the activation and troponin calcium binding of dog cardiac myofibrils by acidic pH. Circulation Research. 55: 382-91. PMID 6235979  0.56
1984 Blanchard EM, Pan BS, Solaro RJ. The effect of acidic pH on the ATPase activity and troponin Ca2+ binding of rabbit skeletal myofilaments. The Journal of Biological Chemistry. 259: 3181-6. PMID 6142051  0.56
1984 Pagani ED, Solaro RJ. Coordination of cardiac myofibrillar and sarcotubular activities in rats exercised by swimming American Journal of Physiology - Heart and Circulatory Physiology. 16.  0.56
1984 Li T, Sperelakin N, Pan BS, Solaro RJ. Excitation-contraction uncoupling by diacetyl monoximes in cardiac muscle Federation Proceedings. 43.  0.56
1983 Solaro RJ, DiSalvo J, Paul RJ. Coordination of metabolism and contractility by phosphorylation in cardiac, skeletal, and smooth muscle. Introduction Federation Proceedings. 42: 7-8. PMID 6848380  0.56
1983 Kranias EG, Solaro RJ. Coordination of cardiac sarcoplasmic reticulum and myofibrillar function by protein phosphorylation Federation Proceedings. 42: 33-38. PMID 6293880  0.56
1983 Pagani ED, Solaro RJ. Swimming exercise, thyroid state, and the distribution of myosin isoenzymes in rat heart American Journal of Physiology - Heart and Circulatory Physiology. 14.  0.56
1982 Shiner JS, Solaro RJ. Activation of thin-filament-regulated muscle by calcium ion: considerations based on nearest-neighbor lattice statistics. Proceedings of the National Academy of Sciences of the United States of America. 79: 4637-41. PMID 6956882  0.56
1982 Martin AF, Pagani ED, Solaro RJ. Thyroxine-induced redistribution of isoenzymes of rabbit ventricular myosin Circulation Research. 50: 117-124. PMID 6459193  0.56
1982 Herzig JW, Peterson JW, Solaro RJ, Rüegg JC. Phosphate and vanadate reduce the efficiency of the chemo-mechanical energy transformation in cardiac muscle. Advances in Experimental Medicine and Biology. 151: 267-281. PMID 6217726  0.56
1982 Solaro RJ, Ruegg JC. Stimulation of Ca++ binding and ATPase activity of dog cardiac myofibrils by AR-L 115BS, a novel cardiotonic agent Circulation Research. 51: 290-294. PMID 6214330  0.56
1982 Kranias EG, Solaro RJ. Phosphorylation of troponin I and phospholamban during catecholamine stimulation of rabbit heart Nature. 298: 182-184. PMID 6211626 DOI: 10.1038/298182a0  0.56
1981 Shiner JS, Solaro RJ. The effects of modifiers on enzyme catalysis: a non-classical nearest neighbor approach. Biophysical Chemistry. 13: 291-306. PMID 7284559 DOI: 10.1016/0301-4622(81)85003-X  0.56
1981 Herzig JW, Peterson JW, Rüegg JC, Solaro RJ. Vanadate and phosphate ions reduce tension and increase cross-bridge kinetics in chemically skinned heart muscle. Biochimica Et Biophysica Acta. 672: 191-6. PMID 6908844 DOI: 10.1016/0304-4165(81)90392-5  0.56
1981 Crouch TH, Holroyde MJ, Collins JH, Solaro RJ, Potter JD. Interaction of calmodulin with skeletal muscle myosin light chain kinase Biochemistry. 20: 6318-6325. PMID 6895471 DOI: 10.1021/bi00525a006  0.56
1981 Johnson JD, Holroyde MJ, Crouch TH, Solaro RJ, Potter JD. Fluorescence studies of the interaction of calmodulin with myosin light chain kinase Journal of Biological Chemistry. 256: 12194-12198. PMID 6895374  0.56
1981 Litten RZ, Martin BJ, Howe ER, Alpert NR, Solaro RJ. Phosphorylation and adenosine triphosphatase activity of myofibrils from thyrotoxic rabbit hearts Circulation Research. 48: 498-501. PMID 6450650  0.56
1981 Silver PJ, Holroyde MJ, Solaro RJ, Disalvo J. Ca2+, calmodulin and cycic AMP-dependent modulation of actin-myosin interactions in aorta Bba - General Subjects. 674: 65-70. PMID 6263347 DOI: 10.1016/0304-4165(81)90347-0  0.56
1981 Martin AF, Pagani ED, Solaro RJ. Thyroxine induced redistribution of isoenzymes of rabbit ventricular myosin Federation Proceedings. 40: 1424.  0.56
1980 Moir AJG, Solaro RJ, Perry SV. The site of phosphorylation of troponin I in the perfused rabbit heart. The effect of adrenaline Biochemical Journal. 185: 505-513. PMID 7396829  0.56
1980 Solaro RJ, Holroyde MJ, Herzig JW, Peterson J. Cardiac relaxation and myofibrillar interactions with phosphate and vanadate. European Heart Journal. 21-7. PMID 6912115  0.56
1980 Holroyde MJ, Robertson SP, Johnson JD, Solaro RJ, Potter JD. The calcium and magnesium binding sites on cardiac troponin and their role in the regulation of myofibrillar adenosine triphosphatase Journal of Biological Chemistry. 255: 11688-11693. PMID 6449512  0.56
1980 Herzig JW, Peterson JW, Solaro RJ. Vanadate and phosphate alter cross-bridge kinetics in skinned cardiac muscle Journal of Muscle Research and Cell Motility. 1: 226-227.  0.56
1980 Kranias EG, Bilezikjian LM, Solaro RJ. Regulation of cardiac sarcoplasmic reticulum in vitro and in vivo Circulation. 62.  0.56
1979 Holroyde MJ, Potter JD, Solaro RJ. The calcium binding properties of phosphorylated and unphosphorylated cardiac and skeletal myosins Journal of Biological Chemistry. 254: 6478-6482. PMID 447729  0.56
1979 Holroyde MJ, Small DAP, Howe E, Solaro RJ. Isolation of cardiac myofibrils and myosin light chains with in vivo levels of light chain phosphorylation Bba - General Subjects. 587: 628-637. PMID 228754 DOI: 10.1016/0304-4165(79)90014-X  0.56
1979 Litten RZ, Solaro RJ, Ford GD. Nature of the calcium regulatory system of bovine arterial actomyosin Journal of Vascular Research. 16: 26-34. DOI: 10.1159/000158187  0.56
1979 Holroyde MJ, Howe E, Solaro RJ. Modification of calcium requirement for activation of cardiac myofibrillar ATPase by cyclic AMP dependent phosphorylation Bba - General Subjects. 586: 63-69. DOI: 10.1016/0304-4165(79)90405-7  0.56
1978 Solaro RJ, Gleason EN. Effect of cross bridge connections on cation selectivity of myofibrillar troponin C Circulation. 58.  0.56
1977 Briggs FN, Poland JL, Solaro RJ. Relative capabilities of sarcoplasmic reticulum in fast and slow mammalian skeletal muscles. The Journal of Physiology. 266: 587-94. PMID 864615 DOI: 10.1113/jphysiol.1977.sp011783  0.56
1977 Litten RZ, Solaro RJ, Ford GD. Properties of the calcium-sensitive components of bovine arterial actomyosin Archives of Biochemistry and Biophysics. 182: 24-32. PMID 142445 DOI: 10.1016/0003-9861(77)90279-X  0.56
1976 Frearson N, Solaro RJ, Perry SV. Changes in phosphorylation of P light chain of myosin in perfused rabbit heart Nature. 264: 801-802. PMID 1012327 DOI: 10.1038/264801a0  0.56
1976 Solaro RJ, Bruni FD, Gleason EN. Effects of ionic strength on calcium binding to rabbit skeletal myofibrils, thin filaments and myosin Bba - Bioenergetics. 449: 304-309. PMID 990297 DOI: 10.1016/0005-2728(76)90142-0  0.56
1976 Solaro RJ, Moir AJG, Perry SV. Phosphorylation of troponin I and the inotropic effect of adrenaline in the perfused rabbit heart Nature. 262: 615-617. PMID 958429 DOI: 10.1038/262615a0  0.56
1976 Cole HA, Frearson N, Moir AJ, Perry SV, Solaro RJ. Phosphorylation of cardiac myofibrillar proteins. Recent Advances in Studies On Cardiac Structure and Metabolism. 11: 111-120. PMID 145626  0.56
1976 Solaro RJ, Shiner JS. Modulation of Ca2+ control of dog and rabbit cardiac myofibrils by Mg2+. Comparison with rabbit skeletal myofibrils. Circulation Research. 39: 8-14. PMID 132310  0.56
1975 Solaro RJ. Calcium regulation of cardiac myofibrillar activation: Effects of MgATP Journal of Supramolecular and Cellular Biochemistry. 3: 368-375. PMID 127891  0.56
1975 Shiner JS, Solaro RJ. Mg2+ effects on cardiac myofibrillar activation Biophysical Journal. 15: 153A.  0.56
1974 Solaro RJ, Briggs FN. Estimating the functional capabilities of sarcoplasmic reticulum in cardiac muscle. Calcium binding. Circulation Research. 34: 531-40. PMID 4826929  0.56
1974 Hess ML, Solaro RJ, Briggs FN. Polyhydroxyl and temperature antagonism of the inhibitory effects of gram-negative endotoxin on the calcium-uptake activity of cardiac sarcoplasmic reticulum. Recent Advances in Studies On Cardiac Structure and Metabolism. 4: 451-60. PMID 4283217  0.56
1974 Solaro RJ, Briggs FN. Calcium conservation and the regulation of myocardial contraction. Recent Advances in Studies On Cardiac Structure and Metabolism. 4: 359-74. PMID 4283215  0.56
1974 Solaro RJ, Wise RM, Shiner JS, Briggs FN. Calcium requirements for cardiac myofibrillar activation. Circulation Research. 34: 525-30. PMID 4275030  0.56
1974 Poland JL, Solaro RJ. Calcium accumulation by sarcoplasmic reticulum of fast and slow twitch muscles Federation Proceedings. 33.  0.56
1971 Solaro RJ, Pang DC, Briggs FN. The purification of cardiac myofibrils with Triton X-100. Biochimica Et Biophysica Acta. 245: 259-62. PMID 4332100 DOI: 10.1016/0005-2728(71)90033-8  0.56
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