R John Solaro - Publications

Affiliations: 
Physiology and Biophysics University of Illinois at Chicago, Chicago, IL, United States 
Area:
Biochemistry, Molecular Biology

321/451 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Shafaatalab S, Li AY, Jayousi F, Maaref Y, Dababneh S, Hamledari H, Baygi DH, Barszczewski T, Ruprai B, Jannati S, Nagalingam R, Cool AM, Langa P, Chiao M, Roston T, Solaro RJ, et al. Mechanisms of Pathogenicity of Hypertrophic Cardiomyopathy-Associated Troponin T (TNNT2) Variant R278C During Development. Biorxiv : the Preprint Server For Biology. PMID 37609317 DOI: 10.1101/2023.06.06.542948  0.393
2023 Solís C, Warren CM, Dittloff K, DiNello E, Solaro RJ, Russell B. Cardiomyocyte external mechanical unloading activates modifications of α-actinin differently from sarcomere-originated unloading. The Febs Journal. PMID 37551968 DOI: 10.1111/febs.16925  0.599
2023 Langa P, Shafaattalab S, Goldspink PH, Wolska BM, Fernandes AA, Tibbits GF, Solaro RJ. A perspective on Notch signalling in progression and arrhythmogenesis in familial hypertrophic and dilated cardiomyopathies. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 378: 20220176. PMID 37122209 DOI: 10.1098/rstb.2022.0176  0.301
2023 Rosas PC, Solaro RJ. Implications of S-glutathionylation of sarcomere proteins in cardiac disorders, therapies, and diagnosis. Frontiers in Cardiovascular Medicine. 9: 1060716. PMID 36762302 DOI: 10.3389/fcvm.2022.1060716  0.364
2022 Solís C, Thompson WC, Peña JR, McDermott-Roe C, Langa P, Warren CM, Chrzanowska M, Wolska BM, Solaro RJ, Goldspink PH. Mechano-growth factor E-domain modulates cardiac contractile function through 14-3-3 protein interactomes. Frontiers in Physiology. 13: 1028345. PMID 36467694 DOI: 10.3389/fphys.2022.1028345  0.313
2022 Warren CM, Halas M, Goldspink PH, Feng HZ, Herren AW, Wolska BM, de Tombe PP, Jin JP, Solaro RJ. Truncation of the N-terminus of cardiac troponin I initiates adaptive remodeling of the myocardial proteosome via phosphorylation of mechano-sensitive signaling pathways. Molecular and Cellular Biochemistry. PMID 35316461 DOI: 10.1007/s11010-022-04414-3  0.411
2022 Halas M, Langa P, Warren CM, Goldspink PH, Wolska BM, Solaro RJ. . Molecular Pharmacology. PMID 35236770 DOI: 10.1124/molpharm.121.000420  0.447
2021 Shafaattalab S, Li AY, Gunawan MG, Kim B, Jayousi F, Maaref Y, Song Z, Weiss JN, Solaro RJ, Qu Z, Tibbits GF. Mechanisms of Arrhythmogenicity of Hypertrophic Cardiomyopathy-Associated Troponin T () Variant I79N. Frontiers in Cell and Developmental Biology. 9: 787581. PMID 34977031 DOI: 10.3389/fcell.2021.787581  0.38
2021 Lertwanakarn T, Suntravat M, Sánchez EE, Wolska BM, Solaro RJ, de Tombe PP, Tachampa K. Negative inotropic mechanisms of β-cardiotoxin in cardiomyocytes by depression of myofilament ATPase activity without activation of the classical β-adrenergic pathway. Scientific Reports. 11: 21154. PMID 34707114 DOI: 10.1038/s41598-021-00282-x  0.724
2021 Warren CM, Halas M, Feng HZ, Wolska BM, Jin JP, Solaro RJ. NH-Terminal Cleavage of Cardiac Troponin I Signals Adaptive Response to Cardiac Stressors. Journal of Cellular Signaling. 2: 162-171. PMID 34541579  0.454
2021 Capote AE, Batra A, Warren CM, Chowdhury SAK, Wolska BM, Solaro RJ, Rosas PC. B-arrestin-2 Signaling Is Important to Preserve Cardiac Function During Aging. Frontiers in Physiology. 12: 696852. PMID 34512376 DOI: 10.3389/fphys.2021.696852  0.325
2021 Solís C, Solaro RJ. Novel insights into sarcomere regulatory systems control of cardiac thin filament activation. The Journal of General Physiology. 153. PMID 33740037 DOI: 10.1085/jgp.202012777  0.381
2020 Lertwanakarn T, Suntravat M, Sanchez EE, Boonhoh W, Solaro RJ, Wolska BM, Martin JL, de Tombe PP, Tachampa K. Suppression of cardiomyocyte functions by β-CTX isolated from the Thai king cobra () venom via an alternative method. The Journal of Venomous Animals and Toxins Including Tropical Diseases. 26: e20200005. PMID 32742278 DOI: 10.1590/1678-9199-Jvatitd-2020-0005  0.743
2020 Lertwanakarn T, Suntravat M, Sanchez EE, Wolska BM, Solaro RJ, de Tombe P, Tachampa K. Beta-cardiotoxin, a novel compound from king cobra venom, suppresses cardiac function via non-beta-adrenergic pathway. Toxicon : Official Journal of the International Society On Toxinology. 177: S58. PMID 32635097 DOI: 10.1016/J.Toxicon.2019.12.133  0.715
2020 Solaro CR, Solaro RJ. StatinImplications of the complex biology and micro-environment of cardiac sarcomeres in the use of high affinity troponin antibodies as serum biomarkers for cardiac disorders. Journal of Molecular and Cellular Cardiology. PMID 32442660 DOI: 10.1016/J.Yjmcc.2020.05.010  0.453
2020 Chowdhury SAK, Warren CM, Simon JN, Ryba DM, Batra A, Varga P, Kranias EG, Tardiff JC, Solaro RJ, Wolska BM. Modifications of Sarcoplasmic Reticulum Function Prevent Progression of Sarcomere-Linked Hypertrophic Cardiomyopathy Despite a Persistent Increase in Myofilament Calcium Response. Frontiers in Physiology. 11: 107. PMID 32210830 DOI: 10.3389/Fphys.2020.00107  0.466
2019 Rosas PC, Warren CM, Creed HA, Trzeciakowski JP, Solaro RJ, Tong CW. Cardiac Myosin Binding Protein-C Phosphorylation Mitigates Age-Related Cardiac Dysfunction: Hope for Better Aging? Jacc. Basic to Translational Science. 4: 817-830. PMID 31998850 DOI: 10.1016/J.Jacbts.2019.06.003  0.45
2019 Ryba DM, Warren CM, Karam CN, Davis RT, Chowdhury SAK, Alvarez MG, McCann M, Liew CW, Wieczorek DF, Varga P, Solaro RJ, Wolska BM. Sphingosine-1-Phosphate Receptor Modulator, FTY720, Improves Diastolic Dysfunction and Partially Reverses Atrial Remodeling in a Tm-E180G Mouse Model Linked to Hypertrophic Cardiomyopathy. Circulation. Heart Failure. 12: e005835. PMID 31684756 DOI: 10.1161/Circheartfailure.118.005835  0.345
2019 Olver TD, Edwards JC, Jurrissen TJ, Veteto AB, Jones JL, Gao C, Rau C, Warren CM, Klutho PJ, Alex L, Ferreira-Nichols SC, Ivey JR, Thorne PK, McDonald KS, Krenz M, ... ... Solaro RJ, et al. Western Diet-Fed, Aortic-Banded Ossabaw Swine: A Preclinical Model of Cardio-Metabolic Heart Failure. Jacc. Basic to Translational Science. 4: 404-421. PMID 31312763 DOI: 10.1016/J.Jacbts.2019.02.004  0.335
2019 Li KL, Methawasin M, Tanner BCW, Granzier HL, Solaro RJ, Dong WJ. Sarcomere length-dependent effects on Ca-troponin regulation in myocardium expressing compliant titin. The Journal of General Physiology. 151: 30-41. PMID 30523116 DOI: 10.1085/Jgp.201812218  0.477
2019 Rosas PC, Warren CM, Batra A, Creed H, Solaro RJ, Tong CW. Abstract 621: Cardiac Myosin Binding Protein-C Phosphorylation in Ser-273 and Ser-282 is Critical to Maintain Cardiac Function During Aging Circulation Research. 125. DOI: 10.1161/Res.125.Suppl_1.621  0.382
2018 Rajan S, Jagatheesan G, Petrashevskaya N, Biesiadecki BJ, Warren CM, Riddle T, Liggett SB, Wolska BM, Solaro RJ, Wieczorek DF. Tropomyosin pseudo-phosphorylation results in dilated cardiomyopathy. The Journal of Biological Chemistry. PMID 30567734 DOI: 10.1074/Jbc.Ra118.004879  0.509
2018 Ghashghaee NB, Li KL, Solaro RJ, Dong WJ. Role of the C-terminus mobile domain of cardiac troponin I in the regulation of thin filament activation in skinned papillary muscle strips. Archives of Biochemistry and Biophysics. PMID 29704484 DOI: 10.1016/J.Abb.2018.04.014  0.423
2018 DeSantiago J, Bare DJ, Varma D, Solaro RJ, Arora R, Banach K. The Loss of p21-Activated Kinase (Pak1) Promotes Atrial Arrhythmic Activity The Role of Pak1 in Atrial Arrhythmia. Heart Rhythm. PMID 29625277 DOI: 10.1016/J.Hrthm.2018.03.041  0.34
2017 Karam CN, Warren CM, Henze M, Banke NH, Lewandowski ED, Solaro RJ. Peroxisome proliferator-activated receptor α expression induces alterations in cardiac myofilaments in a pressure overload model of hypertrophy. American Journal of Physiology. Heart and Circulatory Physiology. ajpheart.00469.2016. PMID 28130336 DOI: 10.1152/Ajpheart.00469.2016  0.479
2017 Ryba DM, Li J, Cowan CL, Russell B, Wolska BM, Solaro RJ. Long-Term Biased β-Arrestin Signaling Improves Cardiac Structure and Function in Dilated Cardiomyopathy. Circulation. PMID 28104714 DOI: 10.1161/Circulationaha.116.024482  0.662
2016 Abraham DM, Davis RT, Warren CM, Mao L, Wolska BM, Solaro RJ, Rockman HA. β-Arrestin mediates the Frank-Starling mechanism of cardiac contractility. Proceedings of the National Academy of Sciences of the United States of America. PMID 27911784 DOI: 10.1073/Pnas.1609308113  0.475
2016 Broughton KM, Li J, Sarmah E, Warren CM, Lin YH, Henze MP, Sanchez-Freire V, Solaro RJ, Russell B. A Myosin Activator improves Actin Assembly and Sarcomere Function of Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes with a Troponin T Point Mutation. American Journal of Physiology. Heart and Circulatory Physiology. ajpheart.00162.2016. PMID 27199119 DOI: 10.1152/Ajpheart.00162.2016  0.559
2016 Li KL, Ghashghaee NB, Solaro RJ, Dong W. Sarcomere length dependent effects on the interaction between cTnC and cTnI in skinned papillary muscle strips. Archives of Biochemistry and Biophysics. PMID 26944554 DOI: 10.1016/J.Abb.2016.02.030  0.415
2016 Solaro RJ. Why we need to understand the mechanics of developing cardiac sarcomeres in humans. The Journal of Physiology. 594: 255. PMID 26767884 DOI: 10.1113/Jp271706  0.398
2016 Li K, Solaro RJ, Dong W. Sarcomere Length Dependent Effects on Ca2+-Induced Troponin Regulation within Chemically Skinned Cardiac Muscle Fibers Biophysical Journal. 110: 465a. DOI: 10.1016/J.Bpj.2015.11.2489  0.467
2015 Huang CL, Solaro RJ, Ke Y, Lei M. Editorial: Ca(2+) Signaling and Heart Rhythm. Frontiers in Physiology. 6: 423. PMID 26793124 DOI: 10.3389/Fphys.2015.00423  0.378
2015 Warren CM, Karam CN, Wolska BM, Kobayashi T, de Tombe PP, Arteaga GM, Bos JM, Ackerman MJ, Solaro RJ. A Green Tea Catechin Normalizes the Enhanced Ca2+ Sensitivity of Myofilaments Regulated by a Hypertrophic Cardiomyopathy Associated Mutation in Human Cardiac Troponin I (K206I). Circulation. Cardiovascular Genetics. PMID 26553696 DOI: 10.1161/Circgenetics.115.001234  0.427
2015 Davis RT, Simon JN, Utter M, Mungai P, Alvarez MG, Chowdhury SA, Heydemann A, Ke Y, Wolska BM, Solaro RJ. Knockout of p21-activated kinase-1 attenuates exercise-induced cardiac remodelling through altered calcineurin signalling. Cardiovascular Research. 108: 335-47. PMID 26464331 DOI: 10.1093/Cvr/Cvv234  0.453
2015 Wilder T, Ryba DM, Wieczorek DF, Wolska BM, Solaro RJ. N-acetylcysteine reverses diastolic dysfunction and hypertrophy in familial hypertrophic cardiomyopathy. American Journal of Physiology. Heart and Circulatory Physiology. 309: H1720-30. PMID 26432840 DOI: 10.1152/Ajpheart.00339.2015  0.512
2015 Solaro RJ. A sarcomeric protein tongue-twister: post-translation, citrullination/deimination and elimination of arginine residues. Cardiovascular Research. 108: 212-4. PMID 26392345 DOI: 10.1093/Cvr/Cvv220  0.507
2015 Utter MS, Ryba DM, Li BH, Wolska BM, Solaro RJ. Omecamtiv mecarbil, a cardiac myosin activator, increases Ca2+-sensitivity in myofilaments with a dilated cardiomyopathy mutant tropomyosin E54K. Journal of Cardiovascular Pharmacology. PMID 26065842 DOI: 10.1097/Fjc.0000000000000286  0.516
2015 Tarigopula M, Davis RT, Mungai PT, Ryba DM, Wieczorek DF, Cowan CL, Violin JD, Wolska BM, Solaro RJ. Cardiac myosin light chain phosphorylation and inotropic effects of a biased ligand, TRV120023, in a dilated cardiomyopathy model. Cardiovascular Research. 107: 226-34. PMID 26045475 DOI: 10.1093/Cvr/Cvv162  0.359
2015 Utter MS, Warren CM, Solaro RJ. Impact of anesthesia and storage on posttranslational modifications of cardiac myofilament proteins. Physiological Reports. 3. PMID 25952935 DOI: 10.14814/Phy2.12393  0.379
2015 Wang Y, Tsui H, Bolton EL, Wang X, Huang CL, Solaro RJ, Ke Y, Lei M. Novel insights into mechanisms for Pak1-mediated regulation of cardiac Ca(2+) homeostasis. Frontiers in Physiology. 6: 76. PMID 25852566 DOI: 10.3389/Fphys.2015.00076  0.523
2015 Rosas PC, Liu Y, Abdalla MI, Thomas CM, Kidwell DT, Dusio GF, Mukhopadhyay D, Kumar R, Baker KM, Mitchell BM, Powers PA, Fitzsimons DP, Patel BG, Warren CM, Solaro RJ, et al. Phosphorylation of cardiac Myosin-binding protein-C is a critical mediator of diastolic function. Circulation. Heart Failure. 8: 582-94. PMID 25740839 DOI: 10.1161/Circheartfailure.114.001550  0.484
2015 Lei M, Wang X, Ke Y, Solaro RJ. Regulation of Ca(2+) transient by PP2A in normal and failing heart. Frontiers in Physiology. 6: 13. PMID 25688213 DOI: 10.3389/Fphys.2015.00013  0.396
2015 Carley AN, Taglieri DM, Bi J, Solaro RJ, Lewandowski ED. Metabolic efficiency promotes protection from pressure overload in hearts expressing slow skeletal troponin I. Circulation. Heart Failure. 8: 119-27. PMID 25424393 DOI: 10.1161/Circheartfailure.114.001496  0.765
2014 Ke Y, Wang X, Jin XY, Solaro RJ, Lei M. PAK1 is a novel cardiac protective signaling molecule. Frontiers of Medicine. 8: 399-403. PMID 25416031 DOI: 10.1007/S11684-014-0380-9  0.542
2014 Cheng Y, Lindert S, Kekenes-Huskey P, Rao VS, Solaro RJ, Rosevear PR, Amaro R, McCulloch AD, McCammon JA, Regnier M. Computational studies of the effect of the S23D/S24D troponin I mutation on cardiac troponin structural dynamics. Biophysical Journal. 107: 1675-85. PMID 25296321 DOI: 10.1016/J.Bpj.2014.08.008  0.432
2014 Simon JN, Chowdhury SA, Warren CM, Sadayappan S, Wieczorek DF, Solaro RJ, Wolska BM. Ceramide-mediated depression in cardiomyocyte contractility through PKC activation and modulation of myofilament protein phosphorylation. Basic Research in Cardiology. 109: 445. PMID 25280528 DOI: 10.1007/S00395-014-0445-6  0.391
2014 Wang Y, Tsui H, Ke Y, Shi Y, Li Y, Davies L, Cartwright EJ, Venetucci L, Zhang H, Terrar DA, Huang CL, Solaro RJ, Wang X, Lei M. Pak1 is required to maintain ventricular Ca²⁺ homeostasis and electrophysiological stability through SERCA2a regulation in mice. Circulation. Arrhythmia and Electrophysiology. 7: 938-48. PMID 25217043 DOI: 10.1161/Circep.113.001198  0.361
2014 Briston SJ, Dibb KM, Solaro RJ, Eisner DA, Trafford AW. Balanced changes in Ca buffering by SERCA and troponin contribute to Ca handling during β-adrenergic stimulation in cardiac myocytes. Cardiovascular Research. 104: 347-54. PMID 25183792 DOI: 10.1093/Cvr/Cvu201  0.416
2014 Nagalingam RS, Sundaresan NR, Noor M, Gupta MP, Solaro RJ, Gupta M. Deficiency of cardiomyocyte-specific microRNA-378 contributes to the development of cardiac fibrosis involving a transforming growth factor β (TGFβ1)-dependent paracrine mechanism. The Journal of Biological Chemistry. 289: 27199-214. PMID 25104350 DOI: 10.1074/Jbc.M114.580977  0.388
2014 Li KL, Rieck D, Solaro RJ, Dong W. In situ time-resolved FRET reveals effects of sarcomere length on cardiac thin-filament activation. Biophysical Journal. 107: 682-93. PMID 25099807 DOI: 10.1016/J.Bpj.2014.05.044  0.406
2014 Burniston JG, Gramolini AO, Solaro RJ. Cardiac proteomics. Biomed Research International. 2014: 903538. PMID 25025073 DOI: 10.1155/2014/903538  0.355
2014 Wang R, Wang Y, Lin WK, Zhang Y, Liu W, Huang K, Terrar DA, Solaro RJ, Wang X, Ke Y, Lei M. Inhibition of angiotensin II-induced cardiac hypertrophy and associated ventricular arrhythmias by a p21 activated kinase 1 bioactive peptide. Plos One. 9: e101974. PMID 25014109 DOI: 10.1371/Journal.Pone.0101974  0.462
2014 Koshman YE, Chu M, Kim T, Kalmanson O, Farjah M, Kumar M, Lewis W, Geenen DL, de Tombe P, Goldspink PH, Solaro RJ, Samarel AM. Cardiomyocyte-specific expression of CRNK, the C-terminal domain of PYK2, maintains ventricular function and slows ventricular remodeling in a mouse model of dilated cardiomyopathy. Journal of Molecular and Cellular Cardiology. 72: 281-91. PMID 24713463 DOI: 10.1016/J.Yjmcc.2014.03.021  0.423
2014 Alegre-Cebollada J, Kosuri P, Giganti D, Eckels E, Rivas-Pardo JA, Hamdani N, Warren CM, Solaro RJ, Linke WA, Fernández JM. S-glutathionylation of cryptic cysteines enhances titin elasticity by blocking protein folding. Cell. 156: 1235-46. PMID 24630725 DOI: 10.1016/J.Cell.2014.01.056  0.404
2014 Alves ML, Dias FA, Gaffin RD, Simon JN, Montminy EM, Biesiadecki BJ, Hinken AC, Warren CM, Utter MS, Davis RT, Sadayappan S, Robbins J, Wieczorek DF, Solaro RJ, Wolska BM. Desensitization of myofilaments to Ca2+ as a therapeutic target for hypertrophic cardiomyopathy with mutations in thin filament proteins. Circulation. Cardiovascular Genetics. 7: 132-43. PMID 24585742 DOI: 10.1161/Circgenetics.113.000324  0.44
2014 Yar S, Monasky MM, Solaro RJ. Maladaptive modifications in myofilament proteins and triggers in the progression to heart failure and sudden death. PflüGers Archiv : European Journal of Physiology. 466: 1189-97. PMID 24488009 DOI: 10.1007/S00424-014-1457-7  0.818
2014 Puglisi JL, Goldspink PH, Gomes AV, Utter MS, Bers DM, Solaro RJ. Influence of a constitutive increase in myofilament Ca(2+)-sensitivity on Ca(2+)-fluxes and contraction of mouse heart ventricular myocytes. Archives of Biochemistry and Biophysics. 552: 50-9. PMID 24480308 DOI: 10.1016/J.Abb.2014.01.019  0.416
2014 Kotlo K, Xing Y, Lather S, Grillon JM, Johnson K, Skidgel RA, Solaro RJ, Danziger RS. PR65A phosphorylation regulates PP2A complex signaling. Plos One. 9: e85000. PMID 24465463 DOI: 10.1371/Journal.Pone.0085000  0.461
2014 DeSantiago J, Bare DJ, Xiao L, Ke Y, Solaro RJ, Banach K. p21-Activated kinase1 (Pak1) is a negative regulator of NADPH-oxidase 2 in ventricular myocytes. Journal of Molecular and Cellular Cardiology. 67: 77-85. PMID 24380729 DOI: 10.1016/J.Yjmcc.2013.12.017  0.419
2014 Li K, Rieck DC, Solaro RJ, Dong W. Monitoring Cardiac Troponin Structural Changes using In-Situ Time-Resolved FRET: Implications on the Regulatory Roles of Cross-Bridges and Sarcomere Length Biophysical Journal. 106: 769a-770a. DOI: 10.1016/J.Bpj.2013.11.4227  0.419
2014 Rieck DC, Zhou Z, Li K, Solaro RJ, Dong W. Truncation of the Mobile Domain of Cardiac Troponin I Results in Biphasic Calcium-Dependent Thin Filament Activation Biophysical Journal. 106: 722a-723a. DOI: 10.1016/J.Bpj.2013.11.3992  0.432
2014 Broughton KM, Sanchez-Freire V, Wu JC, Wolska BM, Solaro RJ, Russell B. Cardiomyopathy Ctnt Mutation in Patient Derived Cardiomyocytes from Induced Pluripotent Stem Cells Affects Sarcomere Structure and Function Biophysical Journal. 106: 566a. DOI: 10.1016/J.Bpj.2013.11.3139  0.545
2014 DeSantiago J, Bare DJ, Ke Y, Solaro RJ, Avitall B, Arora R, Banach K. Increased Risk of Atrial Fibrillation with Attenuated Activity of P21-Activated Kinase Biophysical Journal. 106: 323a. DOI: 10.1016/J.Bpj.2013.11.1860  0.4
2013 Patel BG, Wilder T, Solaro RJ. Novel control of cardiac myofilament response to calcium by S-glutathionylation at specific sites of myosin binding protein C. Frontiers in Physiology. 4: 336. PMID 24312057 DOI: 10.3389/Fphys.2013.00336  0.443
2013 Ke Y, Lei M, Wang X, Solaro RJ. Unique catalytic activities and scaffolding of p21 activated kinase-1 in cardiovascular signaling. Frontiers in Pharmacology. 4: 116. PMID 24098283 DOI: 10.3389/Fphar.2013.00116  0.346
2013 Schulz EM, Wilder T, Chowdhury SA, Sheikh HN, Wolska BM, Solaro RJ, Wieczorek DF. Decreasing tropomyosin phosphorylation rescues tropomyosin-induced familial hypertrophic cardiomyopathy. The Journal of Biological Chemistry. 288: 28925-35. PMID 23960072 DOI: 10.1074/Jbc.M113.466466  0.465
2013 Rieck DC, Li KL, Ouyang Y, Solaro RJ, Dong WJ. Structural basis for the in situ Ca(2+) sensitization of cardiac troponin C by positive feedback from force-generating myosin cross-bridges. Archives of Biochemistry and Biophysics. 537: 198-209. PMID 23896515 DOI: 10.1016/J.Abb.2013.07.013  0.394
2013 Monasky MM, Taglieri DM, Henze M, Warren CM, Utter MS, Soergel DG, Violin JD, Solaro RJ. The β-arrestin-biased ligand TRV120023 inhibits angiotensin II-induced cardiac hypertrophy while preserving enhanced myofilament response to calcium. American Journal of Physiology. Heart and Circulatory Physiology. 305: H856-66. PMID 23873795 DOI: 10.1152/Ajpheart.00327.2013  0.76
2013 Liu W, Zi M, Tsui H, Chowdhury SK, Zeef L, Meng QJ, Travis M, Prehar S, Berry A, Hanley NA, Neyses L, Xiao RP, Oceandy D, Ke Y, Solaro RJ, et al. A novel immunomodulator, FTY-720 reverses existing cardiac hypertrophy and fibrosis from pressure overload by targeting NFAT (nuclear factor of activated T-cells) signaling and periostin. Circulation. Heart Failure. 6: 833-44. PMID 23753531 DOI: 10.1161/Circheartfailure.112.000123  0.516
2013 DeSantiago J, Bare DJ, Ke Y, Sheehan KA, Solaro RJ, Banach K. Functional integrity of the T-tubular system in cardiomyocytes depends on p21-activated kinase 1. Journal of Molecular and Cellular Cardiology. 60: 121-8. PMID 23612118 DOI: 10.1016/J.Yjmcc.2013.04.014  0.448
2013 Yar S, Chowdhury SA, Davis RT, Kobayashi M, Monasky MM, Rajan S, Wolska BM, Gaponenko V, Kobayashi T, Wieczorek DF, Solaro RJ. Conserved Asp-137 is important for both structure and regulatory functions of cardiac α-tropomyosin (α-TM) in a novel transgenic mouse model expressing α-TM-D137L. The Journal of Biological Chemistry. 288: 16235-46. PMID 23609439 DOI: 10.1074/Jbc.M113.458695  0.804
2013 Nagalingam RS, Sundaresan NR, Gupta MP, Geenen DL, Solaro RJ, Gupta M. A cardiac-enriched microRNA, miR-378, blocks cardiac hypertrophy by targeting Ras signaling. The Journal of Biological Chemistry. 288: 11216-32. PMID 23447532 DOI: 10.1074/Jbc.M112.442384  0.369
2013 Solaro RJ, Henze M, Kobayashi T. Integration of troponin I phosphorylation with cardiac regulatory networks. Circulation Research. 112: 355-66. PMID 23329791 DOI: 10.1161/Circresaha.112.268672  0.488
2013 Jeong EM, Monasky MM, Gu L, Taglieri DM, Patel BG, Liu H, Wang Q, Greener I, Dudley SC, Solaro RJ. Tetrahydrobiopterin improves diastolic dysfunction by reversing changes in myofilament properties. Journal of Molecular and Cellular Cardiology. 56: 44-54. PMID 23247392 DOI: 10.1016/J.Yjmcc.2012.12.003  0.8
2013 Nixon BR, Liu B, Scellini B, Tesi C, Piroddi N, Ogut O, Solaro RJ, Ziolo MT, Janssen PM, Davis JP, Poggesi C, Biesiadecki BJ. Tropomyosin Ser-283 pseudo-phosphorylation slows myofibril relaxation. Archives of Biochemistry and Biophysics. 535: 30-8. PMID 23232082 DOI: 10.1016/J.Abb.2012.11.010  0.383
2013 Monasky MM, Taglieri DM, Jacobson AK, Haizlip KM, Solaro RJ, Janssen PM. Post-translational modifications of myofilament proteins involved in length-dependent prolongation of relaxation in rabbit right ventricular myocardium. Archives of Biochemistry and Biophysics. 535: 22-9. PMID 23085150 DOI: 10.1016/J.Abb.2012.10.005  0.791
2013 Henze M, Patrick SE, Hinken A, Scruggs SB, Goldspink P, de Tombe PP, Kobayashi M, Ping P, Kobayashi T, Solaro RJ. New insights into the functional significance of the acidic region of the unique N-terminal extension of cardiac troponin I. Biochimica Et Biophysica Acta. 1833: 823-32. PMID 22940544 DOI: 10.1016/J.Bbamcr.2012.08.012  0.497
2013 DeSantiago J, Bare D, Ke Y, Solaro RJ, Banach K. P21-Activated Kinase (Pak1) is a Negative Regulator of ROS Generation in Ventricular Myocytes Biophysical Journal. 104: 614a. DOI: 10.1016/J.Bpj.2012.11.3401  0.361
2013 Yar S, Chowdhury SA, Turner M, Rajan S, Wolska BM, Gaponenko V, Debold EP, Kobayashi T, Wieczorek DF, Solaro RJ. Altered Flexibility affects Regulatory Functions of Cardiac α-Tropomyosin (α-Tm) in a Novel Transgenic Mouse Model Expressing α-Tm-D137L Biophysical Journal. 104: 448a. DOI: 10.1016/J.Bpj.2012.11.2485  0.818
2012 Ke Y, Lei M, Wang X, Solaro RJ. Novel roles of PAK1 in the heart. Cellular Logistics. 2: 89-94. PMID 23162741 DOI: 10.4161/cl.21497  0.416
2012 Schulz EM, Correll RN, Sheikh HN, Lofrano-Alves MS, Engel PL, Newman G, Schultz JEJ, Molkentin JD, Wolska BM, Solaro RJ, Wieczorek DF. Tropomyosin dephosphorylation results in compensated cardiac hypertrophy Journal of Biological Chemistry. 287: 44478-44489. PMID 23148217 DOI: 10.1074/Jbc.M112.402040  0.566
2012 Lai HL, Grachoff M, McGinley AL, Khan FF, Warren CM, Chowdhury SA, Wolska BM, Solaro RJ, Geenen DL, Wang QT. Maintenance of adult cardiac function requires the chromatin factor Asxl2. Journal of Molecular and Cellular Cardiology. 53: 734-41. PMID 23046516 DOI: 10.1016/J.Yjmcc.2012.08.014  0.441
2012 Hinken AC, Hanft LM, Scruggs SB, Sadayappan S, Robbins J, Solaro RJ, McDonald KS. Protein kinase C depresses cardiac myocyte power output and attenuates myofilament responses induced by protein kinase A. Journal of Muscle Research and Cell Motility. 33: 439-48. PMID 22527640 DOI: 10.1007/S10974-012-9294-9  0.493
2012 Nixon BR, Thawornkaiwong A, Jin J, Brundage EA, Little SC, Davis JP, Solaro RJ, Biesiadecki BJ. AMP-activated protein kinase phosphorylates cardiac troponin I at Ser-150 to increase myofilament calcium sensitivity and blunt PKA-dependent function. The Journal of Biological Chemistry. 287: 19136-47. PMID 22493448 DOI: 10.1074/Jbc.M111.323048  0.507
2012 Knezevic I, Patel A, Sundaresan NR, Gupta MP, Solaro RJ, Nagalingam RS, Gupta M. A novel cardiomyocyte-enriched microRNA, miR-378, targets insulin-like growth factor 1 receptor: implications in postnatal cardiac remodeling and cell survival. The Journal of Biological Chemistry. 287: 12913-26. PMID 22367207 DOI: 10.1074/Jbc.M111.331751  0.34
2012 Lovelock JD, Monasky MM, Jeong EM, Lardin HA, Liu H, Patel BG, Taglieri DM, Gu L, Kumar P, Pokhrel N, Zeng D, Belardinelli L, Sorescu D, Solaro RJ, Dudley SC. Ranolazine improves cardiac diastolic dysfunction through modulation of myofilament calcium sensitivity. Circulation Research. 110: 841-50. PMID 22343711 DOI: 10.1161/Circresaha.111.258251  0.784
2012 Avner BS, Shioura KM, Scruggs SB, Grachoff M, Geenen DL, Helseth DL, Farjah M, Goldspink PH, Solaro RJ. Myocardial infarction in mice alters sarcomeric function via post-translational protein modification. Molecular and Cellular Biochemistry. 363: 203-15. PMID 22160857 DOI: 10.1007/S11010-011-1172-Z  0.831
2012 Monasky MM, Taglieri DM, Patel BG, Chernoff J, Wolska BM, Ke Y, Solaro RJ. p21-activated kinase improves cardiac contractility during ischemia-reperfusion concomitant with changes in troponin-T and myosin light chain 2 phosphorylation. American Journal of Physiology. Heart and Circulatory Physiology. 302: H224-30. PMID 22037191 DOI: 10.1152/Ajpheart.00612.2011  0.807
2012 Jeong E, Monasky MM, Gu L, Taglieri DM, Patel BG, Wang Q, Lardin H, Greener I, Solaro RJ, Dudley SC. Tetrahydrobiopterin Improves Diastolic Heart Failure by Increasing Myofilament Calcium Sensitivity Journal of Cardiac Failure. 18. DOI: 10.1016/J.Cardfail.2012.06.022  0.763
2012 Ke Y, Taglieri DM, Monasky MM, Solaro RJ. Erratum: Inhibition of angiotensin II-induced ventricular hypertrophy and fibrosis by modulation of Pak1 activity (Biophysical Journal (2012) (556a)) Biophysical Journal. 102. DOI: 10.1016/J.Bpj.2012.02.044  0.746
2012 Warren CM, Alves MS, Montminy EM, Simon JN, Gaffin RD, Rajan S, Wieczorek DF, Solaro RJ, Wolska BM. Rescue of a Dilated Cardiomyopathy Mouse Model Caused by a Mutation in Tropomyosin (E54K) by Expression of Slow Skeletal Troponin I Biophysical Journal. 102: 560a. DOI: 10.1016/J.Bpj.2011.11.3051  0.455
2012 Ke Y, Taglieri DM, Michelle MM, Solaro RJ. Inhibition of Angiotensin II-Induced Ventricular Hypertrophy and Fibrosis by Modulation of Pak1 Activity Biophysical Journal. 102. DOI: 10.1016/J.Bpj.2011.11.3032  0.786
2012 DeSantiago J, Bare DJ, Sheehan KA, Ke Y, Solaro RJ, Banach K. P21-Activated Kinase (Pak1) is a Direct Modulator of Cardiac Excitation-Contraction Coupling (ECC) Gain Biophysical Journal. 102: 512a. DOI: 10.1016/J.Bpj.2011.11.2802  0.424
2012 Solaro RJ, Leinwand LA. Role of sarcomeres in cellular tension, shortening, and signaling in cardiac muscle Muscle. 1: 161-172. DOI: 10.1016/B978-0-12-381510-1.00013-2  0.504
2011 Liu W, Zi M, Naumann R, Ulm S, Jin J, Taglieri DM, Prehar S, Gui J, Tsui H, Xiao RP, Neyses L, Solaro RJ, Ke Y, Cartwright EJ, Lei M, et al. Pak1 as a novel therapeutic target for antihypertrophic treatment in the heart. Circulation. 124: 2702-15. PMID 22082674 DOI: 10.1161/Circulationaha.111.048785  0.802
2011 Taglieri DM, Monasky MM, Knezevic I, Sheehan KA, Lei M, Wang X, Chernoff J, Wolska BM, Ke Y, Solaro RJ. Ablation of p21-activated kinase-1 in mice promotes isoproterenol-induced cardiac hypertrophy in association with activation of Erk1/2 and inhibition of protein phosphatase 2A. Journal of Molecular and Cellular Cardiology. 51: 988-96. PMID 21971074 DOI: 10.1016/J.Yjmcc.2011.09.016  0.801
2011 Belin RJ, Sumandea MP, Sievert GA, Harvey LA, Geenen DL, Solaro RJ, de Tombe PP. Interventricular differences in myofilament function in experimental congestive heart failure. PflüGers Archiv : European Journal of Physiology. 462: 795-809. PMID 21927813 DOI: 10.1007/S00424-011-1024-4  0.519
2011 Ai X, Jiang A, Ke Y, Solaro RJ, Pogwizd SM. Enhanced activation of p21-activated kinase 1 in heart failure contributes to dephosphorylation of connexin 43. Cardiovascular Research. 92: 106-14. PMID 21727092 DOI: 10.1093/Cvr/Cvr163  0.45
2011 Egom EE, Mohamed TM, Mamas MA, Shi Y, Liu W, Chirico D, Stringer SE, Ke Y, Shaheen M, Wang T, Chacko S, Wang X, Solaro RJ, Fath-Ordoubadi F, Cartwright EJ, et al. Activation of Pak1/Akt/eNOS signaling following sphingosine-1-phosphate release as part of a mechanism protecting cardiomyocytes against ischemic cell injury. American Journal of Physiology. Heart and Circulatory Physiology. 301: H1487-95. PMID 21705677 DOI: 10.1152/Ajpheart.01003.2010  0.459
2011 Pound KM, Arteaga GM, Fasano M, Wilder T, Fischer SK, Warren CM, Wende AR, Farjah M, Abel ED, Solaro RJ, Lewandowski ED. Expression of slow skeletal TnI in adult mouse hearts confers metabolic protection to ischemia. Journal of Molecular and Cellular Cardiology. 51: 236-43. PMID 21640727 DOI: 10.1016/J.Yjmcc.2011.05.014  0.429
2011 Scruggs SB, Solaro RJ. The significance of regulatory light chain phosphorylation in cardiac physiology. Archives of Biochemistry and Biophysics. 510: 129-34. PMID 21345328 DOI: 10.1016/J.Abb.2011.02.013  0.483
2011 Solaro RJ, Kobayashi T. Protein phosphorylation and signal transduction in cardiac thin filaments. The Journal of Biological Chemistry. 286: 9935-40. PMID 21257760 DOI: 10.1074/Jbc.R110.197731  0.495
2011 Solaro RJ, Stull JT. Thematic minireview series on signaling in cardiac sarcomeres in health and disease. The Journal of Biological Chemistry. 286: 9895. PMID 21257756 DOI: 10.1074/Jbc.R110.214403  0.431
2011 Karam CN, Warren CM, Rajan S, de Tombe PP, Wieczorek DF, Solaro RJ. Expression of tropomyosin-κ induces dilated cardiomyopathy and depresses cardiac myofilament tension by mechanisms involving cross-bridge dependent activation and altered tropomyosin phosphorylation. Journal of Muscle Research and Cell Motility. 31: 315-22. PMID 21221740 DOI: 10.1007/S10974-010-9237-2  0.533
2011 Shioura KM, Farjah M, Geenen DL, Solaro RJ, Goldspink PH. Myofilament calcium sensitization delays decompensated hypertrophy differently between the sexes following myocardial infarction. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 300: R361-8. PMID 21106909 DOI: 10.1152/Ajpregu.00321.2010  0.447
2011 Sheehan KA, Arteaga GM, Hinken AC, Dias FA, Ribeiro C, Wieczorek DF, Solaro RJ, Wolska BM. Functional effects of a tropomyosin mutation linked to FHC contribute to maladaptation during acidosis. Journal of Molecular and Cellular Cardiology. 50: 442-50. PMID 21047515 DOI: 10.1016/J.Yjmcc.2010.10.032  0.418
2011 Sheehan KA, Ke Y, Banach K, Solaro RJ. P21-Activated Kinase-1 and Fty720 Alter Atrial Excitation-Contraction Coupling Biophysical Journal. 100: 80a. DOI: 10.1016/J.Bpj.2010.12.644  0.421
2011 Taglieri DM, Knezevic II, Chernoff J, Solaro RJ, Ke Y. Erk1-Mediated Development of Left Ventricular Cardiac Hypertrophy in a P21 Activated Kinase-1 (Pak1) Knockout Mouse Model Biophysical Journal. 100: 289a. DOI: 10.1016/J.Bpj.2010.12.1783  0.778
2011 Solaro RJ. Modulation of Cardiac Myofilament Activity by Protein Phosphorylation Comprehensive Physiology. DOI: 10.1002/Cphy.Cp020107  0.46
2010 Peña JR, Szkudlarek AC, Warren CM, Heinrich LS, Gaffin RD, Jagatheesan G, del Monte F, Hajjar RJ, Goldspink PH, Solaro RJ, Wieczorek DF, Wolska BM. Neonatal gene transfer of Serca2a delays onset of hypertrophic remodeling and improves function in familial hypertrophic cardiomyopathy. Journal of Molecular and Cellular Cardiology. 49: 993-1002. PMID 20854827 DOI: 10.1016/J.Yjmcc.2010.09.010  0.454
2010 Force T, Bonow RO, Houser SR, Solaro RJ, Hershberger RE, Adhikari B, Anderson ME, Boineau R, Byrne BJ, Cappola TP, Kalluri R, LeWinter MM, Maron MS, Molkentin JD, Ommen SR, et al. Research priorities in hypertrophic cardiomyopathy: report of a Working Group of the National Heart, Lung, and Blood Institute. Circulation. 122: 1130-3. PMID 20837938 DOI: 10.1161/Circulationaha.110.950089  0.408
2010 Jagatheesan G, Rajan S, Ahmed RP, Petrashevskaya N, Boivin G, Arteaga GM, Tae HJ, Liggett SB, Solaro RJ, Wieczorek DF. Striated muscle tropomyosin isoforms differentially regulate cardiac performance and myofilament calcium sensitivity. Journal of Muscle Research and Cell Motility. 31: 227-39. PMID 20803058 DOI: 10.1007/S10974-010-9228-3  0.443
2010 Solaro RJ, Sheehan KA, Lei M, Ke Y. The curious role of sarcomeric proteins in control of diverse processes in cardiac myocytes. The Journal of General Physiology. 136: 13-9. PMID 20584888 DOI: 10.1085/Jgp.201010462  0.433
2010 Avner BS, Hinken AC, Yuan C, Solaro RJ. H2O2 alters rat cardiac sarcomere function and protein phosphorylation through redox signaling. American Journal of Physiology. Heart and Circulatory Physiology. 299: H723-30. PMID 20562337 DOI: 10.1152/Ajpheart.00050.2010  0.81
2010 Solaro RJ, Warren CM, Scruggs SB. Why is it important to analyze the cardiac sarcomere subproteome? Expert Review of Proteomics. 7: 311-4. PMID 20536300 DOI: 10.1586/epr.10.15  0.351
2010 Solaro RJ. Sarcomere control mechanisms and the dynamics of the cardiac cycle. Journal of Biomedicine & Biotechnology. 2010: 105648. PMID 20467475 DOI: 10.1155/2010/105648  0.449
2010 Scruggs SB, Reisdorph R, Armstrong ML, Warren CM, Reisdorph N, Solaro RJ, Buttrick PM. A novel, in-solution separation of endogenous cardiac sarcomeric proteins and identification of distinct charged variants of regulatory light chain. Molecular & Cellular Proteomics : McP. 9: 1804-18. PMID 20445002 DOI: 10.1074/Mcp.M110.000075  0.426
2010 Biesiadecki BJ, Tachampa K, Yuan C, Jin JP, de Tombe PP, Solaro RJ. Removal of the cardiac troponin I N-terminal extension improves cardiac function in aged mice. The Journal of Biological Chemistry. 285: 19688-98. PMID 20410305 DOI: 10.1074/Jbc.M109.086892  0.805
2010 Warren CM, Geenen DL, Helseth DL, Xu H, Solaro RJ. Sub-proteomic fractionation, iTRAQ, and OFFGEL-LC-MS/MS approaches to cardiac proteomics. Journal of Proteomics. 73: 1551-61. PMID 20394843 DOI: 10.1016/J.Jprot.2010.03.016  0.365
2010 Solaro RJ, van der Velden J. Why does troponin I have so many phosphorylation sites? Fact and fancy. Journal of Molecular and Cellular Cardiology. 48: 810-6. PMID 20188739 DOI: 10.1016/J.Yjmcc.2010.02.014  0.51
2010 Lu QW, Hinken AC, Patrick SE, Solaro RJ, Kobayashi T. Phosphorylation of cardiac troponin I at protein kinase C site threonine 144 depresses cooperative activation of thin filaments. The Journal of Biological Chemistry. 285: 11810-7. PMID 20164197 DOI: 10.1074/Jbc.M109.055657  0.507
2010 Ke Y, Sheehan KA, Egom EE, Lei M, Solaro RJ. Novel bradykinin signaling in adult rat cardiac myocytes through activation of p21-activated kinase. American Journal of Physiology. Heart and Circulatory Physiology. 298: H1283-9. PMID 20154261 DOI: 10.1152/Ajpheart.01070.2009  0.507
2010 Lee DI, Vahebi S, Tocchetti CG, Barouch LA, Solaro RJ, Takimoto E, Kass DA. PDE5A suppression of acute beta-adrenergic activation requires modulation of myocyte beta-3 signaling coupled to PKG-mediated troponin I phosphorylation. Basic Research in Cardiology. 105: 337-47. PMID 20107996 DOI: 10.1007/S00395-010-0084-5  0.427
2010 Egom EE, Ke Y, Solaro RJ, Lei M. Cardioprotection in ischemia/reperfusion injury: spotlight on sphingosine-1-phosphate and bradykinin signalling. Progress in Biophysics and Molecular Biology. 103: 142-7. PMID 20080123 DOI: 10.1016/J.Pbiomolbio.2010.01.001  0.398
2010 Rajan S, Jagatheesan G, Karam CN, Alves ML, Bodi I, Schwartz A, Bulcao CF, D'Souza KM, Akhter SA, Boivin GP, Dube DK, Petrashevskaya N, Herr AB, Hullin R, Liggett SB, ... Solaro RJ, et al. Molecular and functional characterization of a novel cardiac-specific human tropomyosin isoform. Circulation. 121: 410-8. PMID 20065163 DOI: 10.1161/Circulationaha.109.889725  0.512
2010 Egom EE, Ke Y, Musa H, Mohamed TM, Wang T, Cartwright E, Solaro RJ, Lei M. FTY720 prevents ischemia/reperfusion injury-associated arrhythmias in an ex vivo rat heart model via activation of Pak1/Akt signaling. Journal of Molecular and Cellular Cardiology. 48: 406-14. PMID 19852968 DOI: 10.1016/J.Yjmcc.2009.10.009  0.356
2010 Warren CM, Geenen DL, Helseth DL, Solaro RJ. Sub-Proteomic Fractionation of Rat Cardiac Tissue: Comparing Ischemic Vs Normal Remote Region with In-Solution Based Proteomics Biophysical Journal. 98. DOI: 10.1016/J.Bpj.2009.12.3942  0.362
2010 Avner BS, Shioura KM, Scruggs SB, Helseth DL, Goldspink PH, Solaro RJ. Alterations to Cardiac Muscle Function and Sarcomeric Proteins Following Myocardial Infarction Biophysical Journal. 98: 543a-544a. DOI: 10.1016/J.Bpj.2009.12.2948  0.829
2010 Karam C, Alves M, Wolsa BM, Rajan S, Wieczorek DF, Solaro RJ. Tropomyosin-Kappa Alters Cardiac Dynamics in a Mouse Heart Model Biophysical Journal. 98: 358a-359a. DOI: 10.1016/J.Bpj.2009.12.1935  0.558
2010 Biesiadecki BJ, Alves ML, Jagatheesan G, Liu B, Scellini B, Tesi C, Davis JP, Poggesi C, Wieczorek DF, Wolska BM, Solaro RJ. Tropomyosin Pseudo-Phosphorylation and Muscle Kinetics Biophysical Journal. 98: 350a. DOI: 10.1016/J.Bpj.2009.12.1893  0.484
2009 Kirk JA, MacGowan GA, Evans C, Smith SH, Warren CM, Mamidi R, Chandra M, Stewart AF, Solaro RJ, Shroff SG. Left ventricular and myocardial function in mice expressing constitutively pseudophosphorylated cardiac troponin I. Circulation Research. 105: 1232-9. PMID 19850940 DOI: 10.1161/Circresaha.109.205427  0.516
2009 Jagatheesan G, Rajan S, Schulz EM, Ahmed RP, Petrashevskaya N, Schwartz A, Boivin GP, Arteaga GM, Wang T, Wang YG, Ashraf M, Liggett SB, Lorenz J, Solaro RJ, Wieczorek DF. An internal domain of beta-tropomyosin increases myofilament Ca(2+) sensitivity. American Journal of Physiology. Heart and Circulatory Physiology. 297: H181-90. PMID 19429821 DOI: 10.1152/Ajpheart.00329.2008  0.432
2009 Engel PL, Hinken A, Solaro RJ. Differential effects of phosphorylation of regions of troponin I in modifying cooperative activation of cardiac thin filaments. Journal of Molecular and Cellular Cardiology. 47: 359-64. PMID 19426736 DOI: 10.1016/J.Yjmcc.2009.04.016  0.441
2009 Solaro RJ. CK-1827452, a sarcomere-directed cardiac myosin activator for acute and chronic heart disease. Idrugs : the Investigational Drugs Journal. 12: 243-51. PMID 19350469  0.434
2009 Warren CM, Kobayashi T, Solaro RJ. Sites of intra- and intermolecular cross-linking of the N-terminal extension of troponin I in human cardiac whole troponin complex. The Journal of Biological Chemistry. 284: 14258-66. PMID 19321456 DOI: 10.1074/Jbc.M807621200  0.365
2009 Hartman TJ, Martin JL, Solaro RJ, Samarel AM, Russell B. CapZ dynamics are altered by endothelin-1 and phenylephrine via PIP2- and PKC-dependent mechanisms. American Journal of Physiology. Cell Physiology. 296: C1034-9. PMID 19295171 DOI: 10.1152/Ajpcell.00544.2008  0.606
2009 Solaro RJ. Maintaining cooperation among cardiac myofilament proteins through thick and thin. The Journal of Physiology. 587: 3. PMID 19119179 DOI: 10.1113/Jphysiol.2008.166751  0.472
2009 Scruggs SB, Hinken AC, Thawornkaiwong A, Robbins J, Walker LA, de Tombe PP, Geenen DL, Buttrick PM, Solaro RJ. Ablation of ventricular myosin regulatory light chain phosphorylation in mice causes cardiac dysfunction in situ and affects neighboring myofilament protein phosphorylation. The Journal of Biological Chemistry. 284: 5097-106. PMID 19106098 DOI: 10.1074/Jbc.M807414200  0.497
2009 Sheehan KA, Ke Y, Wolska BM, Solaro RJ. Expression of active p21-activated kinase-1 induces Ca2+ flux modification with altered regulatory protein phosphorylation in cardiac myocytes. American Journal of Physiology. Cell Physiology. 296: C47-58. PMID 18923061 DOI: 10.1152/Ajpcell.00012.2008  0.409
2009 Jagatheesan G, Schulz EM, Ahmed RP, Petrashevskaya N, Schwartz A, Boivin GP, Arteaga GM, Liggett SB, Solaro RJ, Wieczorek DF. An Internal Domain of Beta Tropomyosin Increases Myofilament Calcium Sensitivity Biophysical Journal. 96: 504a. DOI: 10.1016/J.Bpj.2008.12.2597  0.385
2009 Scruggs SB, Reisdorph R, Buttrick PM, Reisdorph N, Solaro RJ. In-Solution Proteomic Workflow for Purification of Endogenous Sarcomeric Proteins and Identification of Distinct Charged Variants of Regulatory Light Chain Biophysical Journal. 96. DOI: 10.1016/J.Bpj.2008.12.2591  0.388
2009 Wilder T, Hinken AC, Solaro RJ. Altered Myofilament Targeting with Differential PKCδ Activation Biophysical Journal. 96. DOI: 10.1016/J.Bpj.2008.12.2582  0.423
2009 Avner BS, Solaro RJ. Reactive Oxygen Species Alter Activation Of Cardiac Myofilaments And Modify Sarcomeric Proteins Biophysical Journal. 96: 497a. DOI: 10.1016/J.Bpj.2008.12.2565  0.819
2009 Biesiadecki BJ, Thawornkaiwong A, Jin J, Solaro R. Troponin I Ser-150 pseudo-phosphorylation alters cardiac contractile mechanics Biophysical Journal. 96: 227a. DOI: 10.1016/J.Bpj.2008.12.1115  0.425
2009 Warren CM, Kobayashi T, Solaro RJ. Human Cardiac Troponin Cross-Linking and the Functional Consequences Biophysical Journal. 96. DOI: 10.1016/J.Bpj.2008.12.1114  0.327
2008 Yuan C, Solaro RJ. Myofilament proteins: From cardiac disorders to proteomic changes. Proteomics. Clinical Applications. 2: 788-99. PMID 21136879 DOI: 10.1002/Prca.200780076  0.477
2008 Ke Y, Solaro RJ. Use of a decoy peptide to purify p21 activated kinase-1 in cardiac muscle and identification of ceramide-related activation. Biologics : Targets & Therapy. 2: 903-9. PMID 19707468 DOI: 10.2147/Btt.S3870  0.457
2008 Ke Y, Lei M, Solaro RJ. Regulation of cardiac excitation and contraction by p21 activated kinase-1. Progress in Biophysics and Molecular Biology. 98: 238-50. PMID 19351515 DOI: 10.1016/J.Pbiomolbio.2009.01.007  0.385
2008 Baudenbacher F, Schober T, Pinto JR, Sidorov VY, Hilliard F, Solaro RJ, Potter JD, Knollmann BC. Myofilament Ca2+ sensitization causes susceptibility to cardiac arrhythmia in mice. The Journal of Clinical Investigation. 118: 3893-903. PMID 19033660 DOI: 10.1172/Jci36642  0.456
2008 Rudy Y, Ackerman MJ, Bers DM, Clancy CE, Houser SR, London B, McCulloch AD, Przywara DA, Rasmusson RL, Solaro RJ, Trayanova NA, Van Wagoner DR, Varró A, Weiss JN, Lathrop DA. Systems approach to understanding electromechanical activity in the human heart: a national heart, lung, and blood institute workshop summary. Circulation. 118: 1202-11. PMID 18779456 DOI: 10.1161/Circulationaha.108.772715  0.41
2008 Solaro RJ. Multiplex kinase signaling modifies cardiac function at the level of sarcomeric proteins. The Journal of Biological Chemistry. 283: 26829-33. PMID 18567577 DOI: 10.1074/Jbc.R800037200  0.5
2008 Yuan C, Sheng Q, Tang H, Li Y, Zeng R, Solaro RJ. Quantitative comparison of sarcomeric phosphoproteomes of neonatal and adult rat hearts. American Journal of Physiology. Heart and Circulatory Physiology. 295: H647-56. PMID 18552161 DOI: 10.1152/Ajpheart.00357.2008  0.467
2008 Sumandea MP, Rybin VO, Hinken AC, Wang C, Kobayashi T, Harleton E, Sievert G, Balke CW, Feinmark SJ, Solaro RJ, Steinberg SF. Tyrosine phosphorylation modifies protein kinase C δ-dependent phosphorylation of cardiac troponin I Journal of Biological Chemistry. 283: 22680-22689. PMID 18550549 DOI: 10.1074/Jbc.M802396200  0.425
2008 Minami H, Wolska BM, Stojanovic MO, Solaro RJ. Reversal of effects of acidosis on contraction of rat heart myocytes by CGP-48506. Frontiers in Bioscience : a Journal and Virtual Library. 13: 5638-45. PMID 18508612 DOI: 10.2741/3106  0.33
2008 Tachampa K, Kobayashi T, Wang H, Martin AF, Biesiadecki BJ, Solaro RJ, de Tombe PP. Increased cross-bridge cycling kinetics after exchange of C-terminal truncated troponin I in skinned rat cardiac muscle. The Journal of Biological Chemistry. 283: 15114-21. PMID 18378675 DOI: 10.1074/Jbc.M801636200  0.793
2008 Solaro RJ, de Tombe PP. Review focus series: sarcomeric proteins as key elements in integrated control of cardiac function. Cardiovascular Research. 77: 616-8. PMID 18192242 DOI: 10.1093/Cvr/Cvn004  0.5
2008 Solaro RJ, Rosevear P, Kobayashi T. The unique functions of cardiac troponin I in the control of cardiac muscle contraction and relaxation. Biochemical and Biophysical Research Communications. 369: 82-7. PMID 18162178 DOI: 10.1016/J.Bbrc.2007.12.114  0.51
2008 Warren CM, Arteaga GM, Rajan S, Ahmed RP, Wieczorek DF, Solaro RJ. Use of 2-D DIGE analysis reveals altered phosphorylation in a tropomyosin mutant (Glu54Lys) linked to dilated cardiomyopathy. Proteomics. 8: 100-5. PMID 18095372 DOI: 10.1002/Pmic.200700772  0.393
2008 Urboniene QZD, Ornatowska M, Solaro RJ, Christman JW, Xiao L. Cardiac-Specific Overexpression of a Dominant Negative (DN) p67phox Mutant Shows Reduction in Mouse Heart Size Journal of Cardiac Failure. 14. DOI: 10.1016/J.Cardfail.2008.06.012  0.471
2007 Nowak G, Peña JR, Urboniene D, Geenen DL, Solaro RJ, Wolska BM. Correlations between alterations in length-dependent Ca2+ activation of cardiac myofilaments and the end-systolic pressure-volume relation. Journal of Muscle Research and Cell Motility. 28: 415-9. PMID 18365757 DOI: 10.1007/S10974-008-9136-Y  0.516
2007 Howarth JW, Meller J, Solaro RJ, Trewhella J, Rosevear PR. Phosphorylation-dependent conformational transition of the cardiac specific N-extension of troponin I in cardiac troponin. Journal of Molecular Biology. 373: 706-22. PMID 17854829 DOI: 10.1016/J.Jmb.2007.08.035  0.432
2007 Solaro RJ. Mechanisms of the Frank-Starling law of the heart: the beat goes on. Biophysical Journal. 93: 4095-6. PMID 17766360 DOI: 10.1529/Biophysj.107.117200  0.527
2007 Wu SC, Solaro RJ. Protein kinase C zeta. A novel regulator of both phosphorylation and de-phosphorylation of cardiac sarcomeric proteins. The Journal of Biological Chemistry. 282: 30691-8. PMID 17724026 DOI: 10.1074/Jbc.M703670200  0.417
2007 Solaro RJ. Translational medicine with a capital T, troponin T, that is Circulation Research. 101: 114-115. PMID 17641232 DOI: 10.1161/Circresaha.107.157420  0.405
2007 Sheehan KA, Ke Y, Solaro RJ. p21-Activated kinase-1 and its role in integrated regulation of cardiac contractility American Journal of Physiology - Regulatory Integrative and Comparative Physiology. 293. PMID 17609315 DOI: 10.1152/Ajpregu.00253.2007  0.522
2007 Belin RJ, Sumandea MP, Allen EJ, Schoenfelt K, Wang H, Solaro RJ, de Tombe PP. Augmented protein kinase C-alpha-induced myofilament protein phosphorylation contributes to myofilament dysfunction in experimental congestive heart failure. Circulation Research. 101: 195-204. PMID 17556659 DOI: 10.1161/Circresaha.107.148288  0.464
2007 Rajan S, Ahmed RP, Jagatheesan G, Petrashevskaya N, Boivin GP, Urboniene D, Arteaga GM, Wolska BM, Solaro RJ, Liggett SB, Wieczorek DF. Dilated cardiomyopathy mutant tropomyosin mice develop cardiac dysfunction with significantly decreased fractional shortening and myofilament calcium sensitivity. Circulation Research. 101: 205-14. PMID 17556658 DOI: 10.1161/Circresaha.107.148379  0.509
2007 Xiao L, Zhao Q, Du Y, Yuan C, Solaro RJ, Buttrick PM. PKCepsilon increases phosphorylation of the cardiac myosin binding protein C at serine 302 both in vitro and in vivo. Biochemistry. 46: 7054-61. PMID 17503784 DOI: 10.1021/Bi700467K  0.438
2007 Biesiadecki BJ, Kobayashi T, Walker JS, Solaro RJ, de Tombe PP. The troponin C G159D mutation blunts myofilament desensitization induced by troponin I Ser23/24 phosphorylation. Circulation Research. 100: 1486-93. PMID 17446435 DOI: 10.1161/01.Res.0000267744.92677.7F  0.5
2007 Hinken AC, Solaro RJ. A dominant role of cardiac molecular motors in the intrinsic regulation of ventricular ejection and relaxation. Physiology (Bethesda, Md.). 22: 73-80. PMID 17420299 DOI: 10.1152/Physiol.00043.2006  0.349
2007 Jagatheesan G, Rajan S, Petrashevskaya N, Schwartz A, Boivin G, Arteaga GM, Solaro RJ, Liggett SB, Wieczorek DF. Rescue of tropomyosin-induced familial hypertrophic cardiomyopathy mice by transgenesis. American Journal of Physiology. Heart and Circulatory Physiology. 293: H949-58. PMID 17416600 DOI: 10.1152/Ajpheart.01341.2006  0.415
2007 Ke Y, Lei M, Collins TP, Rakovic S, Mattick PA, Yamasaki M, Brodie MS, Terrar DA, Solaro RJ. Regulation of L-type calcium channel and delayed rectifier potassium channel activity by p21-activated kinase-1 in guinea pig sinoatrial node pacemaker cells. Circulation Research. 100: 1317-27. PMID 17413045 DOI: 10.1161/01.Res.0000266742.51389.A4  0.391
2007 Solaro RJ. Nitroxyl effects on myocardium provide new insights into the significance of altered myofilament response to calcium in the regulation of contractility Journal of Physiology. 580: 697. PMID 17347260 DOI: 10.1113/Jphysiol.2007.131649  0.449
2007 Davis JP, Norman C, Kobayashi T, Solaro RJ, Swartz DR, Tikunova SB. Effects of thin and thick filament proteins on calcium binding and exchange with cardiac troponin C. Biophysical Journal. 92: 3195-206. PMID 17293397 DOI: 10.1529/Biophysj.106.095406  0.462
2007 Solaro RJ, Arteaga GM. Heart failure, ischemia/reperfusion injury and cardiac troponin. Advances in Experimental Medicine and Biology. 592: 191-200. PMID 17278366 DOI: 10.1007/978-4-431-38453-3_17  0.391
2007 Solaro RJ, Arteaga GM. Heart failure, ischemia/reperfusion injury and cardiac troponin. Advances in Experimental Medicine and Biology. 592: 191-200. PMID 17278366 DOI: 10.1007/978-4-431-38453-3_17  0.391
2007 Vahebi S, Ota A, Li M, Warren CM, de Tombe PP, Wang Y, Solaro RJ. p38-MAPK induced dephosphorylation of alpha-tropomyosin is associated with depression of myocardial sarcomeric tension and ATPase activity. Circulation Research. 100: 408-15. PMID 17234967 DOI: 10.1161/01.Res.0000258116.60404.Ad  0.456
2007 Bupha-Intr T, Wattanapermpool J, Peña JR, Wolska BM, Solaro RJ. Myofilament response to Ca2+ and Na+/H+ exchanger activity in sex hormone-related protection of cardiac myocytes from deactivation in hypercapnic acidosis American Journal of Physiology - Regulatory Integrative and Comparative Physiology. 292. PMID 17038443 DOI: 10.1152/ajpregu.00376.2006  0.344
2006 Engel PL, Kobayashi T, Biesiadecki B, Davis J, Tikunova S, Wu S, Solaro RJ. Identification of a region of troponin I important in signaling cross-bridge-dependent activation of cardiac myofilaments. The Journal of Biological Chemistry. 282: 183-93. PMID 17099250 DOI: 10.1074/Jbc.M512337200  0.382
2006 Pyle WG, La Rotta G, de Tombe PP, Sumandea MP, Solaro RJ. Control of cardiac myofilament activation and PKC-betaII signaling through the actin capping protein, CapZ. Journal of Molecular and Cellular Cardiology. 41: 537-43. PMID 16870209 DOI: 10.1016/J.Yjmcc.2006.06.006  0.467
2006 McCall SJ, Nassar R, Malouf NN, Saunders AJ, Oakeley AE, Henderson PM, Solaro RJ, Pielak GJ, Alexander KA, Anderson PA. Development and cardiac contractility: cardiac troponin T isoforms and cytosolic calcium in rabbit. Pediatric Research. 60: 276-81. PMID 16857772 DOI: 10.1203/01.Pdr.0000233004.95404.1F  0.407
2006 Belin RJ, Sumandea MP, Kobayashi T, Walker LA, Rundell VL, Urboniene D, Yuzhakova M, Ruch SH, Geenen DL, Solaro RJ, de Tombe PP. Left ventricular myofilament dysfunction in rat experimental hypertrophy and congestive heart failure. American Journal of Physiology. Heart and Circulatory Physiology. 291: H2344-53. PMID 16815982 DOI: 10.1152/Ajpheart.00541.2006  0.496
2006 Biesiadecki BJ, Solaro RJ. When hearts fail so does skeletal muscle: breaking a vicious cycle. Circulation Research. 98: 1456-8. PMID 16794192 DOI: 10.1161/01.Res.0000231259.29646.74  0.438
2006 Kobayashi T, Solaro RJ. Increased Ca2+ affinity of cardiac thin filaments reconstituted with cardiomyopathy-related mutant cardiac troponin I Journal of Biological Chemistry. 281: 13471-13477. PMID 16531415 DOI: 10.1074/Jbc.M509561200  0.395
2006 Scruggs SB, Walker LA, Lyu T, Geenen DL, Solaro RJ, Buttrick PM, Goldspink PH. Partial replacement of cardiac troponin i with a non-phosphorylatable mutant at serines 43/45 attenuates the contractile dysfunction associated with PKCε phosphorylation Journal of Molecular and Cellular Cardiology. 40: 465-473. PMID 16445938 DOI: 10.1016/J.Yjmcc.2005.12.009  0.498
2006 Kass DA, Solaro RJ. Mechanisms and use of calcium-sensitizing agents in the failing heart Circulation. 113: 305-315. PMID 16418450 DOI: 10.1161/Circulationaha.105.542407  0.503
2006 Solaro RJ. Novel Roles of Cardiac Sarcomeric Proteins in Signaling and Signal Transduction Journal of Molecular and Cellular Cardiology. 40: 994. DOI: 10.1016/J.Yjmcc.2006.03.218  0.391
2006 Zhao Q, Xiao L, Du Y, Yuan C, Solaro RJ, Goldspink PH, Buttrick PM. Serine (Ser) 302 of Cardiac Myosin Binding Protein C (cMyBPC) Is a Unique PKCɛ Phosphorylation Site Both In Vivo and In Vitro Journal of Cardiac Failure. 12. DOI: 10.1016/J.Cardfail.2006.06.149  0.427
2005 Vahebi S, Solaro RJ. Cardiac sarcomeric function, small G-protein signaling, and heart failure Panminerva Medica. 47: 133-142. PMID 16462722  0.385
2005 Solaro RJ. Remote control of A-band cardiac thin filaments by the I-Z-I protein network of cardiac sarcomeres Trends in Cardiovascular Medicine. 15: 148-152. PMID 16099379 DOI: 10.1016/J.Tcm.2005.04.007  0.469
2005 Arteaga GM, Warren CM, Milutinovic S, Martin AF, Solaro RJ. Specific enhancement of sarcomeric response to Ca2+ protects murine myocardium against ischemia-reperfusion dysfunction American Journal of Physiology - Heart and Circulatory Physiology. 289. PMID 16024565 DOI: 10.1152/Ajpheart.00520.2005  0.502
2005 Urboniene D, Dias FAL, Peña JR, Walker LA, Solaro RJ, Wolska BM. Expression of Slow Skeletal Troponin I in Adult Mouse Heart Helps to Maintain the Left Ventricular Systolic Function During Respiratory Hypercapnia Circulation Research. 97: 70-77. PMID 15961720 DOI: 10.1161/01.Res.0000173849.68636.1E  0.439
2005 Layland J, Cave AC, Warren C, Grieve DJ, Sparks E, Kentish JC, Solaro RJ, Shah AM. Protection against endotoxemia-induced contractile dysfunction in mice with cardiac-specific expression of slow skeletal troponin I. The Faseb Journal. 19: 1137-1139. PMID 15855227 DOI: 10.1096/Fj.04-2519Fje  0.5
2005 Vahebi S, Kobayashi T, Warren CM, de Tombe PP, Solaro RJ. Functional effects of rho-kinase-dependent phosphorylation of specific sites on cardiac troponin. Circulation Research. 96: 740-7. PMID 15774859 DOI: 10.1161/01.Res.0000162457.56568.7D  0.461
2005 Layland J, Solaro RJ, Shah AM. Regulation of cardiac contractile function by troponin I phosphorylation Cardiovascular Research. 66: 12-21. PMID 15769444 DOI: 10.1016/J.Cardiores.2004.12.022  0.521
2005 Kobayashi T, Solaro RJ. Calcium, thin filaments, and the integrative biology of cardiac contractility Annual Review of Physiology. 67: 39-67. PMID 15709952 DOI: 10.1146/annurev.physiol.67.040403.114025  0.4
2005 Kobayashi T, Yang X, Walker LA, Van Breemen RB, Solaro RJ. A non-equilibrium isoelectric focusing method to determine states of phosphorylation of cardiac troponin I: Identification of Ser-23 and Ser-24 as significant sites of phosphorylation by protein kinase C Journal of Molecular and Cellular Cardiology. 38: 213-218. PMID 15623438 DOI: 10.1016/J.Yjmcc.2004.10.014  0.397
2004 Parmacek MS, Solaro RJ. Biology of the troponin complex in cardiac myocytes. Progress in Cardiovascular Diseases. 47: 159-76. PMID 15736582 DOI: 10.1016/J.Pcad.2004.07.003  0.529
2004 Sorsa T, Pollesello P, Solaro RJ. The contractile apparatus as a target for drugs against heart failure: Interaction of levosimendan, a calcium sensitiser, with cardiac troponin c Molecular and Cellular Biochemistry. 266: 87-107. PMID 15646030 DOI: 10.1023/B:Mcbi.0000049141.37823.19  0.413
2004 Gomes AV, Venkatraman G, Davis JP, Tikunova SB, Engel P, Solaro RJ, Potter JD. Cardiac troponin T isoforms affect the Ca(2+) sensitivity of force development in the presence of slow skeletal troponin I: insights into the role of troponin T isoforms in the fetal heart. The Journal of Biological Chemistry. 279: 49579-87. PMID 15358779 DOI: 10.1074/Jbc.M407340200  0.446
2004 Goldspink PH, Montgomery DE, Walker LA, Urboniene D, McKinney RD, Geenen DL, Solaro RJ, Buttrick PM. Protein kinase Cepsilon overexpression alters myofilament properties and composition during the progression of heart failure. Circulation Research. 95: 424-32. PMID 15242976 DOI: 10.1161/01.Res.0000138299.85648.92  0.527
2004 Sumandea MP, Burkart EM, Kobayashi T, De Tombe PP, Solaro RJ. Molecular and integrated biology of thin filament protein phosphorylation in heart muscle. Annals of the New York Academy of Sciences. 1015: 39-52. PMID 15201148 DOI: 10.1196/Annals.1302.004  0.461
2004 Jagatheesan G, Rajan S, Petrashevskaya N, Schwartz A, Boivin G, Arteaga G, de Tombe PP, Solaro RJ, Wieczorek DF. Physiological significance of troponin T binding domains in striated muscle tropomyosin. American Journal of Physiology. Heart and Circulatory Physiology. 287: H1484-94. PMID 15191887 DOI: 10.1152/Ajpheart.01112.2003  0.461
2004 Kobayashi T, Dong WJ, Burkart EM, Cheung HC, Solaro RJ. Effects of protein kinase C dependent phosphorylation and a familial hypertrophic cardiomyopathy-related mutation of cardiac troponin I on structural transition of troponin C and myofilament activation. Biochemistry. 43: 5996-6004. PMID 15147183 DOI: 10.1021/Bi036073N  0.404
2004 Solaro RJ. The special structure and function of troponin I in regulation of cardiac contraction and relaxation Advances in Experimental Medicine and Biology. 538: 389-402. PMID 15098685 DOI: 10.1007/978-1-4419-9029-7_36  0.493
2004 Pyle WG, Solaro RJ. At the Crossroads of Myocardial Signaling: The Role of Z-Discs in Intracellular Signaling and Cardiac Function Circulation Research. 94: 296-305. PMID 14976140 DOI: 10.1161/01.Res.0000116143.74830.A9  0.463
2004 Layland J, Grieve DJ, Cave AC, Sparks E, Solaro RJ, Shah AM. Essential role of troponin I in the positive inotropic response to isoprenaline in mouse hearts contracting auxotonically. The Journal of Physiology. 556: 835-847. PMID 14966306 DOI: 10.1113/Jphysiol.2004.061176  0.491
2004 Roman BB, Goldspink PH, Spaite E, Urboniene D, McKinney R, Geenen DL, Solaro RJ, Buttrick PM. Inhibition of PKC phosphorylation of cTnI improves cardiac performance in vivo. American Journal of Physiology. Heart and Circulatory Physiology. 286: H2089-95. PMID 14726296 DOI: 10.1152/Ajpheart.00582.2003  0.477
2004 Ke Y, Wang L, Pyle WG, de Tombe PP, Solaro RJ. Intracellular localization and functional effects of P21-activated kinase-1 (Pak1) in cardiac myocytes. Circulation Research. 94: 194-200. PMID 14670848 DOI: 10.1161/01.Res.0000111522.02730.56  0.511
2003 Burkart EM, Arteaga GM, Sumandea MP, Prabhakar R, Wieczorek DF, Solaro RJ. Altered signaling surrounding the C-lobe of cardiac troponin C in myofilaments containing an alpha-tropomyosin mutation linked to familial hypertrophic cardiomyopathy. Journal of Molecular and Cellular Cardiology. 35: 1285-93. PMID 14519438 DOI: 10.1016/S0022-2828(03)00240-2  0.487
2003 Sumandea MP, Pyle WG, Kobayashi T, de Tombe PP, Solaro RJ. Identification of a functionally critical protein kinase C phosphorylation residue of cardiac troponin T. The Journal of Biological Chemistry. 278: 35135-44. PMID 12832403 DOI: 10.1074/Jbc.M306325200  0.435
2003 Jagatheesan G, Rajan S, Petrashevskaya N, Schwartz A, Boivin G, Vahebi S, DeTombe P, Solaro RJ, Labitzke E, Hilliard G, Wieczorek DF. Functional importance of the carboxyl-terminal region of striated muscle tropomyosin. The Journal of Biological Chemistry. 278: 23204-11. PMID 12690096 DOI: 10.1074/Jbc.M303073200  0.41
2003 Konhilas JP, Irving TC, Wolska BM, Jweied EE, Martin AF, Solaro RJ, de Tombe PP. Troponin I in the murine myocardium: influence on length-dependent activation and interfilament spacing. The Journal of Physiology. 547: 951-61. PMID 12562915 DOI: 10.1113/Jphysiol.2002.038117  0.489
2003 Burkart EM, Sumandea MP, Kobayashi T, Nili M, Martin AF, Homsher E, Solaro RJ. Phosphorylation or glutamic acid substitution at protein kinase C sites on cardiac troponin I differentially depress myofilament tension and shortening velocity. The Journal of Biological Chemistry. 278: 11265-72. PMID 12551921 DOI: 10.1074/jbc.M210712200  0.373
2002 Solaro RJ, Varghese J, Marian AJ, Chandra M. Molecular mechanisms of cardiac myofilament activation: modulation by pH and a troponin T mutant R92Q. Basic Research in Cardiology. 97: I102-10. PMID 12479243 DOI: 10.1007/S003950200038  0.379
2002 Arteaga GM, Kobayashi T, Solaro RJ. Molecular actions of drugs that sensitize cardiac myofilaments to Ca2+ Annals of Medicine. 34: 248-258. PMID 12371709 DOI: 10.1080/078538902320322510  0.446
2002 Solaro RJ, Montgomery DM, Wang L, Burkart EM, Ke Y, Vahebi S, Buttrick P. Integration of pathways that signal cardiac growth with modulation of myofilament activity. Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology. 9: 523-33. PMID 12360133 DOI: 10.1067/Mnc.2002.127626  0.411
2002 Pieples K, Arteaga G, Solaro RJ, Grupp I, Lorenz JN, Boivin GP, Jagatheesan G, Labitzke E, DeTombe PP, Konhilas JP, Irving TC, Wieczorek DF. Tropomyosin 3 expression leads to hypercontractility and attenuates myofilament length-dependent Ca(2+) activation. American Journal of Physiology. Heart and Circulatory Physiology. 283: H1344-53. PMID 12234784 DOI: 10.1152/Ajpheart.00351.2002  0.471
2002 Pyle WG, Sumandea MP, Solaro RJ, De Tombe PP. Troponin I serines 43/45 and regulation of cardiac myofilament function. American Journal of Physiology. Heart and Circulatory Physiology. 283: H1215-24. PMID 12181153 DOI: 10.1152/Ajpheart.00128.2002  0.463
2002 Martin AF, Phillips RM, Kumar A, Crawford K, Abbas Z, Lessard JL, de Tombe P, Solaro RJ. Ca(2+) activation and tension cost in myofilaments from mouse hearts ectopically expressing enteric gamma-actin. American Journal of Physiology. Heart and Circulatory Physiology. 283: H642-9. PMID 12124211 DOI: 10.1152/Ajpheart.00890.2001  0.478
2002 Solaro RJ, Burkart EM. Functional Defects in Troponin and the Systems Biology of Heart Failure Journal of Molecular and Cellular Cardiology. 34: 689-693. PMID 12099706 DOI: 10.1006/Jmcc.2002.2028  0.356
2002 Pyle WG, Hart MC, Cooper JA, Sumandea MP, de Tombe PP, Solaro RJ. Actin capping protein: an essential element in protein kinase signaling to the myofilaments. Circulation Research. 90: 1299-306. PMID 12089068 DOI: 10.1161/01.Res.0000024389.03152.22  0.498
2002 Montgomery DE, Wolska BM, Pyle WG, Roman BB, Dowell JC, Buttrick PM, Koretsky AP, Del Nido P, Solaro RJ. alpha-Adrenergic response and myofilament activity in mouse hearts lacking PKC phosphorylation sites on cardiac TnI. American Journal of Physiology. Heart and Circulatory Physiology. 282: H2397-405. PMID 12003851 DOI: 10.1152/Ajpheart.00714.2001  0.51
2002 Wolska BM, Arteaga GM, Peña JR, Nowak G, Phillips RM, Sahai S, de Tombe PP, Martin AF, Kranias EG, Solaro RJ. Expression of slow skeletal troponin I in hearts of phospholamban knockout mice alters the relaxant effect of beta-adrenergic stimulation. Circulation Research. 90: 882-8. PMID 11988489 DOI: 10.1161/01.Res.0000016962.36404.04  0.394
2002 Communal C, Sumandea M, de Tombe P, Narula J, Solaro RJ, Hajjar RJ. Functional consequences of caspase activation in cardiac myocytes. Proceedings of the National Academy of Sciences of the United States of America. 99: 6252-6. PMID 11972044 DOI: 10.1073/Pnas.092022999  0.451
2002 Solaro RJ. ST-H-1 Molecular mechanisms and therapeutics of myofilament Ca2+ — Sensitization Journal of Molecular and Cellular Cardiology. 34. DOI: 10.1016/S0022-2828(02)90371-8  0.319
2002 Solaro RJ. IL-6 Integrated biology and molecular mechanisms of cardiac myofilament activation Journal of Molecular and Cellular Cardiology. 34. DOI: 10.1016/S0022-2828(02)90256-7  0.339
2001 Wolska BM, Vijayan K, Arteaga GM, Konhilas JP, Phillips RM, Kim R, Naya T, Leiden JM, Martin AF, de Tombe PP, Solaro RJ. Expression of slow skeletal troponin I in adult transgenic mouse heart muscle reduces the force decline observed during acidic conditions. The Journal of Physiology. 536: 863-70. PMID 11691878 DOI: 10.1111/J.1469-7793.2001.00863.X  0.435
2001 Prabhakar R, Boivin GP, Grupp IL, Hoit B, Arteaga G, Solaro RJ, Wieczorek DF. A familial hypertrophic cardiomyopathy alpha-tropomyosin mutation causes severe cardiac hypertrophy and death in mice. Journal of Molecular and Cellular Cardiology. 33: 1815-28. PMID 11603924 DOI: 10.1006/Jmcc.2001.1445  0.33
2001 Kentish JC, McCloskey DT, Layland J, Palmer S, Leiden JM, Martin AF, Solaro RJ. Phosphorylation of troponin I by protein kinase A accelerates relaxation and crossbridge cycle kinetics in mouse ventricular muscle. Circulation Research. 88: 1059-65. PMID 11375276 DOI: 10.1161/Hh1001.091640  0.313
2001 Wang X, Li MX, Spyracopoulos L, Beier N, Chandra M, Solaro RJ, Sykes BD. Structure of the C-domain of Human Cardiac Troponin C in Complex with the Ca2+ Sensitizing Drug EMD 57033 Journal of Biological Chemistry. 276: 25456-25466. PMID 11320096 DOI: 10.1074/Jbc.M102418200  0.371
2001 Huang L, Wolska BM, Montgomery DE, Burkart EM, Buttrick PM, Solaro RJ. Increased contractility and altered Ca2+ transients of mouse heart myocytes conditionally expressing PKCβ American Journal of Physiology-Cell Physiology. 280. PMID 11287324 DOI: 10.1152/Ajpcell.2001.280.5.C1114  0.535
2001 Keller RS, Shai SY, Babbitt CJ, Pham CG, Solaro RJ, Valencik ML, Loftus JC, Ross RS. Disruption of integrin function in the murine myocardium leads to perinatal lethality, fibrosis, and abnormal cardiac performance American Journal of Pathology. 158: 1079-1090. PMID 11238056 DOI: 10.1016/S0002-9440(10)64055-2  0.482
2001 Montgomery DE, Chandra M, Huang QQ, Jin JP, Solaro RJ. Transgenic incorporation of skeletal TnT into cardiac myofilaments blunts PKC-mediated depression of force American Journal of Physiology - Heart and Circulatory Physiology. 280: H1011-H1018. PMID 11179042 DOI: 10.1152/Ajpheart.2001.280.3.H1011  0.475
2001 MacGowan GA, Du C, Cowan DB, Stamm C, McGowan FX, Solaro RJ, Koretsky AP, Del Nido PJ. Ischemic dysfunction in transgenic mice expressing troponin I lacking protein kinase C phosphorylation sites. American Journal of Physiology. Heart and Circulatory Physiology. 280: H835-43. PMID 11158984 DOI: 10.1152/Ajpheart.2001.280.2.H835  0.4
2001 Chandra M, Rundell VLM, Tardiff JC, Leinwand LA, De Tombe PP, Solaro RJ. Ca2+ activation of myofilaments from transgenic mouse hearts expressing R92Q mutant cardiac troponin t American Journal of Physiology - Heart and Circulatory Physiology. 280: H705-H713. PMID 11158969 DOI: 10.1152/Ajpheart.2001.280.2.H705  0.379
2001 Pyle W, Half MC, Cooper JA, de Tombe PP, Solaro R. Cardiac actin capping protein is an essential element in protein kinase C signaling to the myofilament Journal of Molecular and Cellular Cardiology. 33: A97. DOI: 10.1016/S0022-2828(01)90386-4  0.425
2000 De Tombe PP, Solaro RJ. Integration of cardiac myofilament activity and regulation with pathways signaling hypertrophy and failure Annals of Biomedical Engineering. 28: 991-1001. PMID 11144684 DOI: 10.1114/1.1312189  0.427
2000 Evans CC, Pena JR, Phillips RM, Muthuchamy M, Wieczorek DF, Solaro RJ, Wolska BM. Altered hemodynamics in transgenic mice harboring mutant tropomyosin linked to hypertrophic cardiomyopathy. American Journal of Physiology. Heart and Circulatory Physiology. 279: H2414-23. PMID 11045979 DOI: 10.1152/Ajpheart.2000.279.5.H2414  0.449
2000 Solaro RJ. Myosin light chain phosphatase: A cinderella of cellular signaling Circulation Research. 87: 173-175. PMID 10926864 DOI: 10.1161/01.Res.87.3.173  0.419
2000 Arteaga GM, Palmiter KA, Leiden JM, Solaro RJ. Attenuation of length dependence of calcium activation in myofilaments of transgenic mouse hearts expressing slow skeletal troponin I. The Journal of Physiology. 526: 541-9. PMID 10922006 DOI: 10.1111/J.1469-7793.2000.T01-1-00541.X  0.464
2000 Abbott MB, Gaponenko V, Abusamhadneh E, Finley N, Li G, Dvoretsky A, Rance M, Solaro RJ, Rosevear PR. Regulatory domain conformational exchange and linker region flexibility in cardiac troponin C bound to cardiac troponin I. The Journal of Biological Chemistry. 275: 20610-7. PMID 10801883 DOI: 10.1074/Jbc.M909252199  0.326
1999 Solaro RJ. Integration of myofilament response to Ca2+ with cardiac pump regulation and pump dynamics American Journal of Physiology. 277. PMID 10644243  0.327
1999 Schwertz DW, Vizgirda V, Solaro RJ, Piano MR, Ryjewski C. Sexual dimorphism in rat left atrial function and response to adrenergic stimulation Molecular and Cellular Biochemistry. 200: 143-153. PMID 10569194 DOI: 10.1023/A:1007011807383  0.381
1999 Dong WJ, Xing J, Villain M, Hellinger M, Robinson JM, Chandra M, Solaro RJ, Umeda PK, Cheung HC. Conformation of the regulatory domain of cardiac muscle troponin C in its complex with cardiac troponin I. The Journal of Biological Chemistry. 274: 31382-90. PMID 10531339 DOI: 10.1074/Jbc.274.44.31382  0.355
1999 Chandra M, Kim JJ, Solaro RJ. An improved method for exchanging troponin subunits in detergent skinned rat cardiac fiber bundles Biochemical and Biophysical Research Communications. 263: 219-223. PMID 10486280 DOI: 10.1006/Bbrc.1999.1341  0.365
1999 Finley N, Abbott MB, Abusamhadneh E, Gaponenko V, Dong W, Gasmi-Seabrook G, Howarth JW, Rance M, Solaro RJ, Cheung HC, Rosevear PR. NMR analysis of cardiac troponin C-troponin I complexes: effects of phosphorylation. Febs Letters. 453: 107-12. PMID 10403385 DOI: 10.1016/S0014-5793(99)00693-6  0.496
1999 Muthuchamy M, Pieples K, Rethinasamy P, Hoit B, Grupp IL, Boivin GP, Wolska B, Evans C, Solaro RJ, Wieczorek DF. Mouse model of a familial hypertrophic cardiomyopathy mutation in α- tropomyosin manifests cardiac dysfunction Circulation Research. 85: 47-56. PMID 10400910 DOI: 10.1161/01.Res.85.1.47  0.441
1999 Gaponenko V, Abusamhadneh E, Abbott MB, Finley N, Gasmi-Seabrook G, Solaro RJ, Rance M, Rosevear PR. Effects of troponin I phosphorylation on conformational exchange in the regulatory domain of cardiac troponin C Journal of Biological Chemistry. 274: 16681-16684. PMID 10358006 DOI: 10.1074/jbc.274.24.16681  0.359
1999 Chandra M, Montgomery DE, Kim JJ, Solaro RJ. The N-terminal region of troponin T is essential for the maximal activation of rat cardiac myofilaments Journal of Molecular and Cellular Cardiology. 31: 867-880. PMID 10329214 DOI: 10.1006/Jmcc.1999.0928  0.481
1999 Fentzke RC, Buck SH, Patel JR, Lin H, Wolska BM, Stojanovic MO, Martin AF, Solaro RJ, Moss RL, Leiden JM. Impaired cardiomyocyte relaxation and diastolic function in transgenic mice expressing slow skeletal troponin I in the heart. The Journal of Physiology. 517: 143-57. PMID 10226156 DOI: 10.1111/J.1469-7793.1999.0143Z.X  0.513
1999 Wolska BM, Keller RS, Evans CC, Palmiter KA, Phillips RM, Muthuchamy M, Oehlenschlager J, Wieczorek DF, de Tombe PP, Solaro RJ. Correlation between myofilament response to Ca2+ and altered dynamics of contraction and relaxation in transgenic cardiac cells that express beta-tropomyosin. Circulation Research. 84: 745-51. PMID 10205142 DOI: 10.1161/01.Res.84.7.745  0.423
1999 Rarick HM, Tang Hp, Guo XD, Martin AF, Solaro RJ. Interactions at the NH2-terminal interface of cardiac troponin I modulate myofilament activation Journal of Molecular and Cellular Cardiology. 31: 363-375. PMID 10093049 DOI: 10.1006/Jmcc.1998.0870  0.476
1998 Powers FM, Fogelson B, Sturgeon C, Solaro RJ, Law WR. Depressed myofilament co-operativity associated with post-cardioplegic myocardial depression Journal of Molecular and Cellular Cardiology. 30: 1779-1787. PMID 9769234 DOI: 10.1006/Jmcc.1998.0742  0.406
1998 Solaro RJ, Rarick HM. Troponin and tropomyosin: Proteins that switch on and tune in the activity of cardiac myofilaments Circulation Research. 83: 471-480. PMID 9734469 DOI: 10.1161/01.Res.83.5.471  0.512
1998 Van Eyk JE, Powers F, Law W, Larue C, Hodges RS, Solaro RJ. Breakdown and release of myofilament proteins during ischemia and ischemia/reperfusion in rat hearts: identification of degradation products and effects on the pCa-force relation. Circulation Research. 82: 261-71. PMID 9468197 DOI: 10.1161/01.Res.82.2.261  0.445
1998 Rethinasamy P, Muthuchamy M, Hewett T, Boivin G, Wolska BM, Evans C, Solaro RJ, Wieczorek DF. Molecular and physiological effects of α-tropomyosin ablation in the mouse Circulation Research. 82: 116-123. PMID 9440710 DOI: 10.1161/01.Res.82.1.116  0.359
1998 Arteaga GM, Lap SD, Wolska BM, Kecskes S, Solaro RJ. Functional studies in human cardiac tissue obtained from endomyocardial biopsies Critical Care Medicine. 26. DOI: 10.1097/00003246-199801001-00144  0.375
1998 Kitada Y, Solaro RJ. The role of phosphorylation of troponin T and I by protein kinase a or c -dependent pathway in the myofilament Ca2+-sensitizing effects of MCI-154 and levosimendan Journal of Cardiac Failure. 4: 102. DOI: 10.1016/S1071-9164(98)90440-7  0.386
1998 Solaro RJ. Heart failure and molecular signaling in cardiac myofilaments Journal of Cardiac Failure. 4: 41-42. DOI: 10.1016/S1071-9164(98)90278-0  0.458
1997 Fraker LD, Eyk VJ, Solaro RJ. Reversal of phosphate induced decreases in force by the benzimidazole pyridazinone, UD-CG 212 CL, in myofilaments from human ventricle Molecular and Cellular Biochemistry. 176: 83-88. PMID 9406148 DOI: 10.1023/A:1006827012495  0.346
1997 Wolska BM, Averyhart-Fullard V, Omachi A, Stojanović MO, Kallen RG, Solaro RJ. Changes in Thyroid State Affect pHiand Nai+Homeostasis in Rat Ventricular Myocytes Journal of Molecular and Cellular Cardiology. 29: 2653-2663. PMID 9344760 DOI: 10.1006/Jmcc.1997.0495  0.437
1997 Chandra M, Dong WJ, Pan BS, Cheung HC, Solaro RJ. Effects of protein kinase A phosphorylation on signaling between cardiac troponin I and the N-terminal domain of cardiac troponin C. Biochemistry. 36: 13305-11. PMID 9341222 DOI: 10.1021/Bi9710129  0.381
1997 Rarick HM, Tu XH, Solaro RJ, Martin AF. The C terminus of cardiac troponin I is essential for full inhibitory activity and Ca2+ sensitivity of rat myofibrils Journal of Biological Chemistry. 272: 26887-26892. PMID 9341121 DOI: 10.1074/jbc.272.43.26887  0.363
1997 Spyracopoulos L, Li MX, Sia SK, Gagné SM, Chandra M, Solaro RJ, Sykes BD. Calcium-induced structural transition in the regulatory domain of human cardiac troponin C. Biochemistry. 36: 12138-46. PMID 9315850 DOI: 10.1021/Bi971223D  0.358
1997 Dong WJ, Chandra M, Xing J, She M, Solaro RJ, Cheung HC. Phosphorylation-induced distance change in a cardiac muscle troponin I mutant. Biochemistry. 36: 6754-61. PMID 9184157 DOI: 10.1021/bi9622276  0.308
1996 Powers FM, Palmiter KA, Solaro RJ. E-1020, a water soluble imidazopyridine, has direct effects on Ca2+-dependent force and ATP hydrolysis of canine and bovine cardiac myofilaments Molecular and Cellular Biochemistry. 160: 33-39. PMID 8901452  0.311
1996 Rarick HM, Opgenorth TJ, Von Geldern TW, Wu-Wong JR, Solaro RJ. An essential myosin light chain peptide induces supramaximal stimulation of cardiac myofibrillar ATPase activity Journal of Biological Chemistry. 271: 27039-27043. PMID 8900193 DOI: 10.1074/Jbc.271.43.27039  0.402
1996 Babu A, Sonnenblick EH, Gulati J, Solaro RJ, Van Eyk J. Altered interactions among thin filament proteins modulate cardiac function: A clarification [1] Journal of Molecular and Cellular Cardiology. 28: 1829-1831. PMID 8877793 DOI: 10.1006/jmcc.1996.0173  0.326
1996 Wolska BM, Solaro RJ. Method for isolation of adult mouse cardiac myocytes for studies of contraction and microfluorimetry. The American Journal of Physiology. 271: H1250-5. PMID 8853365 DOI: 10.1152/ajpheart.1996.271.3.H1250  0.305
1996 Wolska BM, Kitada Y, Palmiter KA, Westfall MV, Johnson MD, Solaro RJ. CGP-48506 increases contractility of ventricular myocytes and myofilaments by effects on actin-myosin reaction. The American Journal of Physiology. 270: H24-32. PMID 8769730 DOI: 10.1152/ajpheart.1996.270.1.H24  0.315
1996 Wolska BM, Stojanovic MO, Luo W, Kranias EG, Solaro RJ. Effect of ablation of phospholamban on dynamics of cardiac myocyte contraction and intracellular Ca2+ American Journal of Physiology - Cell Physiology. 271. PMID 8760070 DOI: 10.1152/Ajpcell.1996.271.1.C391  0.326
1996 Solaro RJ, Van Eyk J. Altered interactions among thin filament proteins modulate cardiac function Journal of Molecular and Cellular Cardiology. 28: 217-230. PMID 8729055 DOI: 10.1006/jmcc.1996.0021  0.324
1996 Palmiter KA, Kitada Y, Muthuchamy M, Wieczorek DF, Solaro RJ. Exchange of β- for α-tropomyosin in hearts of transgenic mice induces changes in thin filament response to Ca2+, strong cross-bridge binding, and protein phosphorylation Journal of Biological Chemistry. 271: 11611-11614. PMID 8662805 DOI: 10.1074/Jbc.271.20.11611  0.493
1996 Luo W, Wolska BM, Grupp IL, Harrer JM, Haghighi K, Ferguson DG, Slack JP, Grupp G, Doetschman T, Solaro RJ, Kranias EG. Phospholamban gene dosage effects in the mammalian heart. Circulation Research. 78: 839-47. PMID 8620604 DOI: 10.1161/01.Res.78.5.839  0.531
1996 Solaro RJ. Troponin C - troponin I interactions and molecular signalling in cardiac myofilaments. Advances in Experimental Medicine and Biology. 382: 109-15. PMID 8540387 DOI: 10.1007/978-1-4615-1893-8_12  0.346
1996 Powers FM, Palmiter KA, Solaro RJ. E-1020, A Water Soluble Imidazopyridine, Has Direct Effects On Ca2+-Dependent Force And Atp Hydrolysis Of Canine And Bovine Cardiac Myofilaments Molecular and Cellular Biochemistry. 160: 33-39. DOI: 10.1007/978-1-4613-1279-6_4  0.424
1996 Wolska BM, Solaro RJ. Method for isolation of adult mouse cardiac myocytes for studies of contraction and microfluorimetry American Journal of Physiology - Heart and Circulatory Physiology. 40.  0.303
1995 Edes I, Kiss E, Kitada Y, Powers FM, Papp JG, Kranias EG, Solaro RJ. Effects of Levosimendan, a cardiotonic agent targeted to troponin C, on cardiac function and on phosphorylation and Ca2+ sensitivity of cardiac myofibrils and sarcoplasmic reticulum in guinea pig heart. Circulation Research. 77: 107-13. PMID 7788868 DOI: 10.1161/01.Res.77.1.107  0.498
1995 Noland TA, Guo X, Raynor RL, Jideama NM, Averyhart-Fullard V, Solaro RJ, Kuo JF. Cardiac troponin I mutants. Phosphorylation by protein kinases C and A and regulation of Ca(2+)-stimulated MgATPase of reconstituted actomyosin S-1. The Journal of Biological Chemistry. 270: 25445-54. PMID 7592712 DOI: 10.1074/jbc.270.43.25445  0.314
1995 Wattanapermpool J, Guo X, Solaro RJ. The unique amino-terminal peptide of cardiac troponin I regulates myofibrillar activity only when it is phosphorylated Journal of Molecular and Cellular Cardiology. 27: 1383-1391. PMID 7473784 DOI: 10.1006/jmcc.1995.0131  0.34
1994 Guo X, Wattanapermpool J, Palmiter KA, Murphy AM, Solaro RJ. Mutagenesis of Cardiac Troponin I: Role of the Unique NH2-Terminal Peptide in Myofilament Activation Journal of Biological Chemistry. 269: 15210-15216. PMID 8195157  0.332
1994 Ball KL, Solaro RJ. Discoordinate Regulation of Contractile Protein Gene Expression in the Senescent Rat Myocardium Journal of Molecular and Cellular Cardiology. 26: 519-525. PMID 8072007 DOI: 10.1006/jmcc.1994.1062  0.351
1994 Solaro RJ. Heart failure and the response of cardiac myofilaments to Ca2+ Heart Failure. 10: 150-155.  0.411
1993 Solaro RJ, Gambassi G, Warshaw DM, Keller MR, Spurgeon HA, Beier N, Lakatta EG. Stereoselective actions of thiadiazinones on canine cardiac myocytes and myofilaments. Circulation Research. 73: 981-90. PMID 8222092 DOI: 10.1161/01.res.73.6.981  0.349
1993 Solaro RJ, Powers FM, Gao L, Gwathmey JK. Control of myofilament activation in heart failure Circulation. 87.  0.338
1992 Solaro RJ. Myosin and why hearts fail Circulation. 85: 1945-1947. PMID 1572051  0.331
1992 Solaro RJ. Modulation of the response of cardiac myofilaments to Ca2 Journal of Molecular and Cellular Cardiology. 24: 12. DOI: 10.1016/0022-2828(92)90067-A  0.437
1991 Solaro RJ. Functional significance of differences in isoform population of thin filament proteins in developing heart Journal of Molecular and Cellular Cardiology. 23. DOI: 10.1016/0022-2828(91)91369-3  0.397
1990 Murphy AM, Solaro RJ. Developmental difference in the stimulation of cardiac myofibrillar Mg<sup>2+</sup>-ATPase activity by calmidazolium Pediatric Research. 28: 46-47. PMID 2143010  0.332
1990 McAuliffe JJ, Gao L, Solaro RJ. Changes in myofibrillar activation and troponin C Ca2+ binding associated with troponin T isoform switching in developing rabbit heart Circulation Research. 66: 1204-1216. PMID 2139820  0.35
1990 Westfall MV, Solaro RJ. Alterations in myofibrillar function and protein profiles after complete global ischemia in rat hearts Circulation Research. 70: 302-313. PMID 1531186  0.367
1989 Herzig JW, Botelho LH, Solaro RJ. Myofibrillar Ca++ activation and heart failure - Ca++ sensitization by the cardiotonic agent APP 201-533 Basic Research in Cardiology. 84: 117-124. PMID 2818453 DOI: 10.1007/BF02650351  0.374
1989 Fujino K, Sperelakis N, Solaro RJ. Direct effects of pimobendan on cardiac myofilaments Progress in Clinical and Biological Research. 315: 602-603. PMID 2798516  0.339
1989 Edes I, Solaro RJ, Kranias EG. Changes in phosphoinositide turnover in isolated guinea pig hearts stimulated with isoproterenol Circulation Research. 65: 989-996. PMID 2551534 DOI: 10.1161/01.Res.65.4.989  0.336
1989 Rapundalo ST, Solaro RJ, Kranias EG. Inotropic responses to isoproterenol and phosphodiesterase inhibitors in intact guinea pig hearts: Comparison of cyclic AMP levels and phosphorylation of sarcoplasmic reticulum and myofibrillar proteins Circulation Research. 64: 104-111. PMID 2535795 DOI: 10.1161/01.Res.64.1.104  0.301
1989 Solaro RJ, El-Salehl SC, Kentish JC. Ca2+, pH and the regulation of cardiac myofilament force and ATPase activity Molecular and Cellular Biochemistry. 89: 163-167. PMID 2530435 DOI: 10.1007/Bf00220770  0.383
1989 Solaro RJ, Fujino K, Sperelakis N. The positive inotropic effect of pimobendan involves stereospecific increases in the calcium sensitivity of cardiac myofilaments Journal of Cardiovascular Pharmacology. 14: S7-S12. PMID 2478795  0.308
1988 Jakab G, Rapundalo ST, Solaro RJ, Kranias EG. Phosphorylation of phospholipids in isolated guinea pig hearts stimulated with isoprenaline Biochemical Journal. 251: 189-194. PMID 3390153 DOI: 10.1042/Bj2510189  0.351
1988 Garvey JL, Kranias EG, Solaro RJ. Phosphorylation of C-protein, troponin I and phospholamban in isolated rabbit hearts Biochemical Journal. 249: 709-714. PMID 2895634 DOI: 10.1042/Bj2490709  0.366
1988 Fujino K, Sperelakis N, Solaro RJ. Sensitization of dog and guinea pig heart myofilaments to Ca2+ activation and the inotropic effect of pimobendan: Comparison with milrinone Circulation Research. 63: 911-922. PMID 2846200  0.321
1987 El-Saleh SC, Solaro RJ. Calmidazolium, a calmodulin antagonist, stimulates calcium-troponin C and calcium-calmodulin-dependent activation of striated muscle myofilaments Journal of Biological Chemistry. 262: 17240-17246. PMID 2960681  0.374
1986 Solaro RJ, Bousquet P, Johnson JD. Stimulation of cardiac myofilament force, ATPase activity and troponin C Ca++ binding by bepridil Journal of Pharmacology and Experimental Therapeutics. 238: 502-507. PMID 2942677  0.329
1986 Rapundalo ST, Grupp I, Grupp G, Abdul Matlib M, Solaro RJ, Schwartz A. Myocardial actions of milrinone: characterization of its mechanism of action. Circulation. 73: III134-44. PMID 2417746  0.323
1985 Kranias EG, Garvey JL, Srivastava RD, Solaro RJ. Phosphorylation and functional modifications of sarcoplasmic reticulum and myofibrils in isolated rabbit hearts stimulated with isoprenaline Biochemical Journal. 226: 113-121. PMID 3156585 DOI: 10.1042/Bj2260113  0.379
1984 Imai K, Wang T, Millard RW, Ashraf M, Kranias EG, Asano G, Grassi de Gende AO, Nagao T, Solaro RJ, Schwartz A. Ischaemia-induced changes in canine cardiac sarcoplasmic reticulum. Cardiovascular Research. 17: 696-709. PMID 6228297 DOI: 10.1093/Cvr/17.11.696  0.369
1983 Kranias EG, Solaro RJ. Coordination of cardiac sarcoplasmic reticulum and myofibrillar function by protein phosphorylation Federation Proceedings. 42: 33-38. PMID 6293880  0.44
1983 Pagani ED, Solaro RJ. Swimming exercise, thyroid state, and the distribution of myosin isoenzymes in rat heart. The American Journal of Physiology. 245: H713-20. PMID 6139025 DOI: 10.1152/ajpheart.1983.245.5.H713  0.329
1983 Pagani ED, Solaro RJ. Swimming exercise, thyroid state, and the distribution of myosin isoenzymes in rat heart American Journal of Physiology - Heart and Circulatory Physiology. 14.  0.329
1982 Robertson SP, Johnson JD, Holroyde MJ, Kranias EG, Potter JD, Solaro RJ. The effect of troponin I phosphorylation on the Ca2+-binding properties of the Ca2+-regulatory site of bovine cardiac troponin Journal of Biological Chemistry. 257: 260-263. PMID 7053370  0.311
1982 Herzig JW, Peterson JW, Solaro RJ, Rüegg JC. Phosphate and vanadate reduce the efficiency of the chemo-mechanical energy transformation in cardiac muscle. Advances in Experimental Medicine and Biology. 151: 267-281. PMID 6217726  0.335
1982 Kranias EG, Solaro RJ. Phosphorylation of troponin I and phospholamban during catecholamine stimulation of rabbit heart Nature. 298: 182-184. PMID 6211626 DOI: 10.1038/298182A0  0.434
1981 Litten RZ, Martin BJ, Howe ER, Alpert NR, Solaro RJ. Phosphorylation and adenosine triphosphatase activity of myofibrils from thyrotoxic rabbit hearts Circulation Research. 48: 498-501. PMID 6450650  0.329
1980 Moir AJG, Solaro RJ, Perry SV. The site of phosphorylation of troponin I in the perfused rabbit heart. The effect of adrenaline Biochemical Journal. 185: 505-513. PMID 7396829  0.352
1980 Schwartz A, Adams RJ, Grupp I, Grupp G, Holroyde MJ, Millard RW, Solaro RJ, Wallick ET. Effects of vanadate on myocardial function Basic Research in Cardiology. 75: 444-451. PMID 6449925 DOI: 10.1007/Bf01908409  0.334
1980 Solaro RJ, Holroyde MJ, Wang T, Matlib MA, Grupp I, Grupp G, Schwartz A. Effects of vanadate on biochemical and contractile properties of rabbit hearts. Journal of Cardiovascular Pharmacology. 2: 445-52. PMID 6156342 DOI: 10.1097/00005344-198007000-00011  0.31
1980 Wang T, Tsai LI, Solaro RJ, Grassi de Gende AO, Schwartz A. Effects of potassium on vanadate inhibition of sarcoplasmic reticulum Ca2+-ATPase from dog cardiac and rabbit skeletal muscle. Biochemical and Biophysical Research Communications. 91: 356-61. PMID 160227 DOI: 10.1016/0006-291X(79)90626-0  0.309
1980 Kranias EG, Bilezikjian LM, Solaro RJ. Regulation of cardiac sarcoplasmic reticulum in vitro and in vivo Circulation. 62.  0.364
1976 Solaro RJ, Moir AJG, Perry SV. Phosphorylation of troponin I and the inotropic effect of adrenaline in the perfused rabbit heart Nature. 262: 615-617. PMID 958429 DOI: 10.1038/262615a0  0.363
1976 Cole HA, Frearson N, Moir AJ, Perry SV, Solaro RJ. Phosphorylation of cardiac myofibrillar proteins. Recent Advances in Studies On Cardiac Structure and Metabolism. 11: 111-120. PMID 145626  0.394
1975 Solaro RJ. Calcium regulation of cardiac myofibrillar activation: Effects of MgATP Journal of Supramolecular and Cellular Biochemistry. 3: 368-375. PMID 127891  0.306
Low-probability matches (unlikely to be authored by this person)
1980 Solaro RJ, Holroyde MJ, Herzig JW, Peterson J. Cardiac relaxation and myofibrillar interactions with phosphate and vanadate. European Heart Journal. 21-7. PMID 6912115  0.299
1994 Ball KL, Johnson MD, Solaro RJ. Isoform specific interactions of troponin I and troponin C determine pH sensitivity of myofibrillar Ca2+ activation Biochemistry. 33: 8464-8471. PMID 8031779  0.298
2023 Langa P, Marszalek RJ, Warren CM, Chowdhury SK, Halas M, Batra A, Rafael-Clyke K, Bacon A, Goldspink PH, Solaro RJ, Wolska BM. Altered coronary artery function, arteriogenesis and endothelial YAP signaling in postnatal hypertrophic cardiomyopathy. Frontiers in Physiology. 14: 1136852. PMID 37064918 DOI: 10.3389/fphys.2023.1136852  0.298
1981 Martin AF, Pagani ED, Solaro RJ. Thyroxine induced redistribution of isoenzymes of rabbit ventricular myosin Federation Proceedings. 40: 1424.  0.296
1991 Solaro RJ. Regulation of Ca<sup>2+</sup>-signaling in cardiac myofilaments Medicine and Science in Sports and Exercise. 23: 1145-1148. PMID 1758291  0.294
1984 Pagani ED, Solaro RJ. Coordination of cardiac myofibrillar and sarcotubular activities in rats exercised by swimming American Journal of Physiology - Heart and Circulatory Physiology. 16.  0.292
1981 Silver PJ, Holroyde MJ, Solaro RJ, Disalvo J. Ca2+, calmodulin and cycic AMP-dependent modulation of actin-myosin interactions in aorta Bba - General Subjects. 674: 65-70. PMID 6263347 DOI: 10.1016/0304-4165(81)90347-0  0.292
2009 Abraham SJ, Kobayashi T, Solaro RJ, Gaponenko V. Differences in lysine pKa values may be used to improve NMR signal dispersion in reductively methylated proteins. Journal of Biomolecular Nmr. 43: 239-46. PMID 19280122 DOI: 10.1007/S10858-009-9306-2  0.291
1985 Pagani ED, Solaro RJ. Coordination of cardiac myofibrillar and sarcotubular activities in rats exercised by swimming. The American Journal of Physiology. 247: H909-15. PMID 6239553 DOI: 10.1152/ajpheart.1984.247.6.H909  0.291
1997 Dong WJ, Chandra M, Xing J, Solaro RJ, Cheung HC. Conformation of the N-terminal segment of a monocysteine mutant of troponin I from cardiac muscle. Biochemistry. 36: 6745-53. PMID 9184156 DOI: 10.1021/bi962226d  0.29
2010 Solaro RJ. The activity of cardiac myocytes reflects a confluence of a multitude of electrical and chemical signals that promote and control the ability of the myocytes to shorten and develop force. Journal of Molecular and Cellular Cardiology. 48: 809. PMID 20152840 DOI: 10.1016/j.yjmcc.2010.02.006  0.289
1991 Martin AF, Ball K, Gao L, Kumar P, Solaro RJ. Identification and functional significance of troponin I isoforms in neonatal rat heart myofibrils Circulation Research. 69: 1244-1252. PMID 1934354  0.289
2019 Moss RL, Solaro RJ. The enduring relationship between myosin enzymatic activity and the speed of muscle contraction. The Journal of General Physiology. PMID 30890556 DOI: 10.1085/Jgp.201912323  0.289
2004 Yang X, Wu H, Kobayashi T, Solaro RJ, van Breemen RB. Enhanced ionization of phosphorylated peptides during MALDI TOF mass spectrometry. Analytical Chemistry. 76: 1532-6. PMID 14987115 DOI: 10.1021/Ac035203V  0.288
1985 Li T, Sperelakis N, Teneick RE, Solaro RJ. Effects of diacetyl monoxime on cardiac excitation-contraction coupling Journal of Pharmacology and Experimental Therapeutics. 232: 688-695. PMID 3156242  0.287
1976 Solaro RJ, Shiner JS. Modulation of Ca2+ control of dog and rabbit cardiac myofibrils by Mg2+. Comparison with rabbit skeletal myofibrils. Circulation Research. 39: 8-14. PMID 132310  0.286
1987 Pan BS, Solaro RJ. Calcium-binding properties of troponin C in detergent-skinned heart muscle fibers Journal of Biological Chemistry. 262: 7839-7849. PMID 3584144  0.285
1975 Shiner JS, Solaro RJ. Mg2+ effects on cardiac myofibrillar activation Biophysical Journal. 15: 153A.  0.283
2021 Rayani K, Seffernick J, Li AY, Davis JP, Spuches AM, Van Petegem F, Solaro RJ, Lindert S, Tibbits GF. Binding of calcium and magnesium to human cardiac Troponin C. The Journal of Biological Chemistry. 100350. PMID 33548225 DOI: 10.1016/j.jbc.2021.100350  0.283
1997 Fogelson BG, Powers FM, Sturgeon C, Solaro RJ, Law WR. Cellular basis for post-cardioplegic cardiac dysfunction Faseb Journal. 11.  0.282
1998 Powers FM, Farias S, Minami H, Martin AF, Solaro RJ, Law WR. Cardiac myofilament protein function is altered during sepsis. Journal of Molecular and Cellular Cardiology. 30: 967-78. PMID 9618237 DOI: 10.1006/jmcc.1998.0661  0.281
1999 Solaro RJ. Troponin I, stunning, hypertrophy, and failure of the heart Circulation Research. 84: 122-124. PMID 9915781  0.28
1979 Holroyde MJ, Potter JD, Solaro RJ. The calcium binding properties of phosphorylated and unphosphorylated cardiac and skeletal myosins Journal of Biological Chemistry. 254: 6478-6482. PMID 447729  0.28
1983 Solaro RJ, DiSalvo J, Paul RJ. Coordination of metabolism and contractility by phosphorylation in cardiac, skeletal, and smooth muscle. Introduction Federation Proceedings. 42: 7-8. PMID 6848380  0.279
2020 Rosas PC, Batra A, Capote A, Warren C, Halas M, Bello YB, Solaro R. DELETION OF P21-ACTIVATED KINASE-1 WORSENS AGE RELATED CARDIAC DYSFUNCTION IN FEMALES Journal of the American College of Cardiology. 75: 683. DOI: 10.1016/s0735-1097(20)31310-3  0.279
1995 Wattanapermpool J, Reiser PJ, Solaro RJ. Troponin I isoforms and differential effects of acidic pH on soleus and cardiac myofilaments American Journal of Physiology - Cell Physiology. 268. PMID 7864071  0.279
1990 Pan BS, Palmiter KA, Plonczynski M, Solaro RJ. Slowly exchanging calcium binding sites unique to cardiac/slow muscle troponin C Journal of Molecular and Cellular Cardiology. 22: 1117-1124. PMID 2095435 DOI: 10.1016/0022-2828(90)90075-D  0.279
1995 Powers FM, Solaro RJ. Caffeine alters cardiac myofilament activity and regulation independently of Ca2+ binding to troponin C American Journal of Physiology - Cell Physiology. 268. PMID 7611352  0.278
2020 Yan J, Bare DJ, DeSantiago J, Zhao W, Mei Y, Chen Z, Ginsburg KS, Solaro RJ, Wolska BM, Bers DM, Chen SW, Ai X. JNK2, A Newly-Identified SERCA2 Enhancer, Augments an Arrhythmic [Ca] Leak-Load Relationship. Circulation Research. PMID 33334123 DOI: 10.1161/CIRCRESAHA.120.318409  0.277
1986 Solaro RJ, Kumar P, Blanchard EM, Martin AF. Differential effects of pH on calcium activation of myofilaments of adult and perinatal dog hearts. Evidence for developmental differences in thin filament regulation. Circulation Research. 58: 721-9. PMID 2940029  0.274
2021 Batra A, Warren CM, Ke Y, McCann M, Halas M, Capote AE, Liew CW, Solaro RJ, Rosas PC. Deletion of P21-activated kinase-1 induces age-dependent increased visceral adiposity and cardiac dysfunction in female mice. Molecular and Cellular Biochemistry. PMID 33389497 DOI: 10.1007/s11010-020-03993-3  0.272
2019 Moss RL, de Tombe PP, Solaro RJ. Toward an understanding of the regulation of myofibrillar function. The Journal of General Physiology. 151: 1-2. PMID 30578329 DOI: 10.1085/Jgp.201812288  0.271
2019 Capote AE, Ryba DM, Chowdhury S, Rosas PC, Solaro RJ, Dias FA, Wolska BM. Abstract 460: Sex-Related Changes in Physiological Cardiac Hypertrophy in Beta Arrestin-2 KO mice Circulation Research. 125. DOI: 10.1161/res.125.suppl_1.460  0.271
1980 Holroyde MJ, Robertson SP, Johnson JD, Solaro RJ, Potter JD. The calcium and magnesium binding sites on cardiac troponin and their role in the regulation of myofibrillar adenosine triphosphatase Journal of Biological Chemistry. 255: 11688-11693. PMID 6449512  0.27
1982 Solaro RJ, Ruegg JC. Stimulation of Ca++ binding and ATPase activity of dog cardiac myofibrils by AR-L 115BS, a novel cardiotonic agent Circulation Research. 51: 290-294. PMID 6214330  0.27
2023 Phillips EH, Bindokas VP, Jung D, Teamer J, Kitajewski JK, Solaro RJ, Wolska BM, Lee SS. Three-dimensional spatial quantitative analysis of cardiac lymphatics in the mouse heart. Biorxiv : the Preprint Server For Biology. PMID 36778334 DOI: 10.1101/2023.02.01.526338  0.269
2002 Li X, Misik AJ, Rieder CV, Solaro RJ, Lowen A, Fliegel L. Thyroid hormone receptor alpha 1 regulates expression of the Na+/H+ exchanger (NHE1) Journal of Biological Chemistry. 277: 28656-28662. PMID 12039959 DOI: 10.1074/Jbc.M203221200  0.266
1976 Frearson N, Solaro RJ, Perry SV. Changes in phosphorylation of P light chain of myosin in perfused rabbit heart Nature. 264: 801-802. PMID 1012327 DOI: 10.1038/264801a0  0.265
1974 Solaro RJ, Wise RM, Shiner JS, Briggs FN. Calcium requirements for cardiac myofibrillar activation. Circulation Research. 34: 525-30. PMID 4275030  0.265
2023 Phillips EH, Bindokas VP, Jung D, Teamer J, Kitajewski JK, Solaro RJ, Wolska BM, Lee SS. Three-dimensional spatial quantitative analysis of cardiac lymphatics in the mouse heart. Microcirculation (New York, N.Y. : 1994). e12826. PMID 37605603 DOI: 10.1111/micc.12826  0.265
2022 Rayani K, Hantz ER, Haji-Ghassemi O, Li AY, Spuches AM, Van Petegem F, Solaro RJ, Lindert S, Tibbits GF. The effect of Mg on Ca binding to cardiac troponin C in hypertrophic cardiomyopathy associated TNNC1 variants. The Febs Journal. PMID 35838319 DOI: 10.1111/febs.16578  0.265
2021 Solaro RJ, Rosas PC, Langa P, Warren CM, Wolska BM, Goldspink PH. Mechanisms of troponin release into serum in cardiac injury associated with COVID-19 patients. International Journal of Cardiology and Cardiovascular Diseases. 1: 41-47. PMID 34734211 DOI: 10.46439/cardiology.1.006  0.264
1989 Solaro RJ, el-Saleh SC, Kentish J, Meyer A, Martin A. Transitions in isoform populations of thick and thin filament proteins and calcium activation of force and ATP hydrolysis by cardiac myofilaments. Progress in Clinical and Biological Research. 315: 487-502. PMID 2529568  0.263
2020 Goldspink PH, Warren CM, Kitajewski J, Wolska BM, Solaro RJ. A Perspective on Personalized Therapies in Hypertrophic Cardiomyopathy. Journal of Cardiovascular Pharmacology. PMID 33298734 DOI: 10.1097/FJC.0000000000000968  0.261
1993 Westfall MV, Wahler GM, Solaro RJ. A highly specific benzimidazole pyridazinone reverses phosphate-induced changes in cardiac myofilament activation Biochemistry. 32: 10464-10470. PMID 8399192  0.261
1979 Holroyde MJ, Small DAP, Howe E, Solaro RJ. Isolation of cardiac myofibrils and myosin light chains with in vivo levels of light chain phosphorylation Bba - General Subjects. 587: 628-637. PMID 228754 DOI: 10.1016/0304-4165(79)90014-X  0.261
1971 Solaro RJ, Pang DC, Briggs FN. The purification of cardiac myofibrils with Triton X-100. Biochimica Et Biophysica Acta. 245: 259-62. PMID 4332100 DOI: 10.1016/0005-2728(71)90033-8  0.261
1984 Li T, Sperelakin N, Pan BS, Solaro RJ. Excitation-contraction uncoupling by diacetyl monoximes in cardiac muscle Federation Proceedings. 43.  0.257
1997 Li MX, Gagné SM, Spyracopoulos L, Kloks CP, Audette G, Chandra M, Solaro RJ, Smillie LB, Sykes BD. NMR studies of Ca2+ binding to the regulatory domains of cardiac and E41A skeletal muscle troponin C reveal the importance of site I to energetics of the induced structural changes. Biochemistry. 36: 12519-25. PMID 9376356 DOI: 10.1021/Bi971222L  0.256
2001 Prabhakar R, Boivin GP, grupp I, Artega G, Aronow B, Solaro R, Wieczorek DF. A mouse model for α-tropomyosin mutation that causes familial hypertrophic cardiomyopathy Journal of Molecular and Cellular Cardiology. 33: A96. DOI: 10.1016/S0022-2828(01)90381-5  0.256
1999 Gasmi-Seabrook GM, Howarth JW, Finley N, Abusamhadneh E, Gaponenko V, Brito RM, Solaro RJ, Rosevear PR. Solution structures of the C-terminal domain of cardiac troponin C free and bound to the N-terminal domain of cardiac troponin I. Biochemistry. 38: 8313-22. PMID 10387077 DOI: 10.1021/Bi9902642  0.253
1999 Meehan J, Piano MR, Solaro RJ, Kennedy JM. Heavy long-term ethanol consumption induces an alpha- to beta-myosin heavy chain isoform transition in rat Basic Research in Cardiology. 94: 481-488. PMID 10651160 DOI: 10.1007/s003950050164  0.251
1980 Herzig JW, Peterson JW, Solaro RJ. Vanadate and phosphate alter cross-bridge kinetics in skinned cardiac muscle Journal of Muscle Research and Cell Motility. 1: 226-227.  0.247
1974 Solaro RJ, Briggs FN. Estimating the functional capabilities of sarcoplasmic reticulum in cardiac muscle. Calcium binding. Circulation Research. 34: 531-40. PMID 4826929  0.245
1988 Whitmer JT, Kumar P, Solaro RJ. Calcium transport properties of cardiac sarcoplasmic reticulum from cardiomyopathic Syrian hamsters (BIO 53.58 and 14.6): Evidence for a quantitative defect in dilated myopathic hearts not evident in hypertrophic hearts Circulation Research. 62: 81-85. PMID 2961480  0.244
2017 Nagalingam RS, Sundaresan NR, Noor M, Gupta MP, Solaro RJ, Gupta M. Deficiency of cardiomyocyte-specific microRNA-378 contributes to the development of cardiac fibrosis involving a transforming growth factor β (TGFβ1)-dependent paracrine mechanism. The Journal of Biological Chemistry. 292: 5124. PMID 28341712 DOI: 10.1074/jbc.A114.580977  0.244
1989 Just H, Solaro RJ. Pharmacotherapy of congestive heart failure Journal of Cardiovascular Pharmacology. 14.  0.242
1974 Hess ML, Solaro RJ, Briggs FN. Polyhydroxyl and temperature antagonism of the inhibitory effects of gram-negative endotoxin on the calcium-uptake activity of cardiac sarcoplasmic reticulum. Recent Advances in Studies On Cardiac Structure and Metabolism. 4: 451-60. PMID 4283217  0.242
1982 Martin AF, Pagani ED, Solaro RJ. Thyroxine-induced redistribution of isoenzymes of rabbit ventricular myosin Circulation Research. 50: 117-124. PMID 6459193  0.241
1996 Noland TA, Raynor RL, Jideama NM, Guo X, Kazanietz MG, Blumberg PM, Solaro RJ, Kuo JF. Differential regulation of cardiac actomyosin S-1 MgATPase by protein kinase C isozyme-specific phosphorylation of specific sites in cardiac troponin I and its phosphorylation site mutants. Biochemistry. 35: 14923-31. PMID 8942657 DOI: 10.1021/bi9616357  0.241
2017 Nagalingam RS, Sundaresan NR, Gupta MP, Geenen DL, Solaro RJ, Gupta M. A cardiac-enriched microRNA, miR-378, blocks cardiac hypertrophy by targeting Ras signaling. The Journal of Biological Chemistry. 292: 5123. PMID 28341711 DOI: 10.1074/jbc.A112.442384  0.238
1994 Averyhart-Fullard V, Fraker LD, Murphy AM, Solaro RJ. Differential Regulation of Slow-skeletal and Cardiac Troponin I mRNA during Development and by Thyroid Hormone in Rat Heart Journal of Molecular and Cellular Cardiology. 26: 609-616. PMID 8072015 DOI: 10.1006/jmcc.1994.1073  0.238
1979 Holroyde MJ, Howe E, Solaro RJ. Modification of calcium requirement for activation of cardiac myofibrillar ATPase by cyclic AMP dependent phosphorylation Bba - General Subjects. 586: 63-69. DOI: 10.1016/0304-4165(79)90405-7  0.236
2004 Maughan D, Alpert N, Lewinter M, Solaro RJ, Holubarsch C, Yamada K, Warshaw D. Conference report: fifth international conference on muscle energetics, July 2001. Journal of Muscle Research and Cell Motility. 25: 667-670. PMID 15750851 DOI: 10.1007/S10974-002-7989-Z  0.236
1991 Gwathmey JK, Hajjar RJ, Solaro RJ. Contractile deactivation and uncoupling of crossbridges. Effects of 2,3-butanedione monoxime on mammalian myocardium Circulation Research. 69: 1280-1292. PMID 1934358  0.236
2007 Lei M, Ke Y, Solaro RJ. Pak1: steps towards understanding the regulatory mechanisms of pacemaker function of the heart. Future Cardiology. 3: 473-6. PMID 19804297 DOI: 10.2217/14796678.3.5.473  0.235
1988 Fujino K, Sperelakis N, Solaro RJ. Differential effects of d- and l-pimobendan on cardiac myofilament calcium sensitivity Journal of Pharmacology and Experimental Therapeutics. 247: 519-523. PMID 3183951  0.235
1984 Shiner JS, Solaro RJ. The hill coefficient for the Ca2+-activation of striated muscle contraction. Biophysical Journal. 46: 541-3. PMID 6498270 DOI: 10.1016/S0006-3495(84)84051-5  0.229
1988 Solaro RJ, Lee JA, Kentish JC, Allen DG. Effects of acidosis on ventricular muscle from adult and neonatal rats Circulation Research. 63: 779-787. PMID 3168178 DOI: 10.1161/01.RES.63.4.779  0.228
1994 Krudy GA, Kleerekoper Q, Guo X, Howarth JW, Solaro RJ, Rosevear PR. NMR studies delineating spatial relationships within the cardiac troponin I-troponin C complex. The Journal of Biological Chemistry. 269: 23731-5. PMID 8089144  0.225
1972 Solaro RJ, Gertz EW, Briggs FN. Sucrose antagonism of drug and temperature effects on cardiac sarcoplasmic reticulum. Biochimica Et Biophysica Acta. 255: 751-6. PMID 5020223  0.224
1997 Palmiter KA, Solaro RJ. Molecular mechanisms regulating the myofilament response to Ca2+: Implications of mutations causal for familial hypertrophic cardiomyopathy Basic Research in Cardiology, Supplement. 92: 63-74. PMID 9202846  0.219
1992 Westfall MV, Wahler GM, Fujino K, Solaro RJ. Electrophysiological actions of the pimobendan metabolite, UD-CG 212 Cl, in guinea pig myocardium Journal of Pharmacology and Experimental Therapeutics. 260: 58-63. PMID 1346167  0.218
1999 Solaro RJ. Is calcium the 'cure' for dilated cardiomyopathy? Nature Medicine. 5: 1353-1354. PMID 10581071 DOI: 10.1038/70916  0.209
2007 Ke Y, Lum H, Solaro RJ. Inhibition of endothelial barrier dysfunction by P21-activated kinase-1. Canadian Journal of Physiology and Pharmacology. 85: 281-8. PMID 17612635 DOI: 10.1139/y06-100  0.209
2012 Solaro RJ, Rao MC. Kate Bárány: a life of science, teaching, and service. Journal of Muscle Research and Cell Motility. 33: 369-71. PMID 22614738 DOI: 10.1007/S10974-012-9301-1  0.206
1986 Rouslin W, Erickson JL, Solaro RJ. Effects of oligomycin and acidosis on rates of ATP depletion in ischemic heart muscle American Journal of Physiology - Heart and Circulatory Physiology. 250. PMID 2937313  0.205
2023 Perike S, Gonzalez-Gonzalez FJ, Abu-Taha I, Damen FW, Lizama KS, Aboonabi A, Capote AE, Aguilar-Sanchez Y, Levin B, Han Z, Sridhar A, Grand J, Martin J, Akar JG, Warren CM, ... Solaro RJ, et al. Myosin Light Chain Dephosphorylation by PPP1R12C Promotes Atrial Hypocontractility in Atrial Fibrillation. Biorxiv : the Preprint Server For Biology. PMID 37131731 DOI: 10.1101/2023.04.19.537590  0.204
2010 Solaro RJ, de Tombe PP. Reply to Smith letter: Controversy persists after over 100 years of the Frank-Starling mechanism Journal of Molecular and Cellular Cardiology. 49: 709. DOI: 10.1016/J.Yjmcc.2010.07.004  0.203
1990 Dieckman LJ, Solaro RJ. Effect of thyroid status on thin-filament Ca2+ regulation and expression of troponin I in perinatal and adult rat hearts Circulation Research. 67: 344-351. PMID 2142896  0.2
1994 Reiser PJ, Westfall MV, Schiaffino S, Solaro RJ. Tension production and thin-filament protein isoforms in developing rat myocardium American Journal of Physiology - Heart and Circulatory Physiology. 267. PMID 7943406  0.198
1981 Herzig JW, Peterson JW, Rüegg JC, Solaro RJ. Vanadate and phosphate ions reduce tension and increase cross-bridge kinetics in chemically skinned heart muscle. Biochimica Et Biophysica Acta. 672: 191-6. PMID 6908844 DOI: 10.1016/0304-4165(81)90392-5  0.197
1988 El-Saleh SC, Solaro RJ. Troponin I enhances acidic pH-induced depression of Ca2+ binding to the regulatory sites in skeletal troponin C Journal of Biological Chemistry. 263: 3274-3278. PMID 2830278  0.196
1981 Crouch TH, Holroyde MJ, Collins JH, Solaro RJ, Potter JD. Interaction of calmodulin with skeletal muscle myosin light chain kinase Biochemistry. 20: 6318-6325. PMID 6895471 DOI: 10.1021/Bi00525A006  0.193
1999 Piano MR, Rosenblum C, Solaro RJ, Schwertz D. Calcium sensitivity and the effect of the calcium sensitizing drug pimobendan in the alcoholic isolated rat atrium Journal of Cardiovascular Pharmacology. 33: 237-242. PMID 10028931 DOI: 10.1097/00005344-199902000-00009  0.193
1984 Blanchard EM, Pan BS, Solaro RJ. The effect of acidic pH on the ATPase activity and troponin Ca2+ binding of rabbit skeletal myofilaments. The Journal of Biological Chemistry. 259: 3181-6. PMID 6142051  0.193
1993 Kawamura A, Wahler GM, Solaro RJ. Rwj-24517, a positive inotropic agent, has novel effects on action potentials in guinea pig myocardium Journal of Cardiovascular Pharmacology. 22: 519-525. PMID 7505352  0.189
2022 Solaro RJ. Widely cited publications of Michael Bárány in 1964 and 1967 as tipping points in understanding myosin molecular motors. Archives of Biochemistry and Biophysics. 727: 109319. PMID 35709967 DOI: 10.1016/j.abb.2022.109319  0.187
1984 Blanchard EM, Solaro RJ. Inhibition of the activation and troponin calcium binding of dog cardiac myofibrils by acidic pH. Circulation Research. 55: 382-91. PMID 6235979  0.182
1986 El-Saleh SC, Potter JD, Solaro RJ. Alteration of actin-tropomyosin interaction in 2,4-pentanedione-treated rabbit skeletal myofibrils Journal of Biological Chemistry. 261: 14646-14650. PMID 2945819  0.178
2022 Solaro RJ. On 'Comparative studies of rabit cardiac and skeletal myosins' by M.Bárány, E.Gaetjens, K.Bárány, E.Karp. Archives of Biochemistry and Biophysics. 726: 109300. PMID 35709968 DOI: 10.1016/j.abb.2022.109300  0.177
1985 Pan B, Solaro RJ. Effects of sarcomere length on the force-pCa relation and troponin C calcium binding of chemically skinned fibers of canine ventricular muscle Federation Proceedings. 44.  0.175
1974 Solaro RJ, Briggs FN. Calcium conservation and the regulation of myocardial contraction. Recent Advances in Studies On Cardiac Structure and Metabolism. 4: 359-74. PMID 4283215  0.172
1995 Kleerekoper Q, Howarth JW, Guo X, Solaro RJ, Rosevear PR. Cardiac troponin I induced conformational changes in cardiac troponin C as monitored by NMR using site-directed spin and isotope labeling Biochemistry. 34: 13343-13352. PMID 7577919 DOI: 10.1021/Bi00041A010  0.169
1977 Briggs FN, Poland JL, Solaro RJ. Relative capabilities of sarcoplasmic reticulum in fast and slow mammalian skeletal muscles. The Journal of Physiology. 266: 587-94. PMID 864615 DOI: 10.1113/jphysiol.1977.sp011783  0.152
1976 Solaro RJ, Bruni FD, Gleason EN. Effects of ionic strength on calcium binding to rabbit skeletal myofibrils, thin filaments and myosin Bba - Bioenergetics. 449: 304-309. PMID 990297 DOI: 10.1016/0005-2728(76)90142-0  0.147
2020 Marszalek R, Chowdhury SA, Hałas M, Batra A, Warren C, Tardiff J, Solaro R, Wolska B. CORONARY INSUFFICIENCY UNDERLIES FIBROTIC HCM PROGRESSION Journal of the American College of Cardiology. 75: 1045. DOI: 10.1016/S0735-1097(20)31672-7  0.147
1985 Godt RE, Fender KJ, Pan BS, Solaro RJ. Myosin light chain phosphorylation hastens relaxation of skinned skeletal muscle fibers Federation Proceedings. 44.  0.146
1982 Shiner JS, Solaro RJ. Activation of thin-filament-regulated muscle by calcium ion: considerations based on nearest-neighbor lattice statistics. Proceedings of the National Academy of Sciences of the United States of America. 79: 4637-41. PMID 6956882  0.13
1981 Johnson JD, Holroyde MJ, Crouch TH, Solaro RJ, Potter JD. Fluorescence studies of the interaction of calmodulin with myosin light chain kinase Journal of Biological Chemistry. 256: 12194-12198. PMID 6895374  0.123
1974 Poland JL, Solaro RJ. Calcium accumulation by sarcoplasmic reticulum of fast and slow twitch muscles Federation Proceedings. 33.  0.116
1977 Litten RZ, Solaro RJ, Ford GD. Properties of the calcium-sensitive components of bovine arterial actomyosin Archives of Biochemistry and Biophysics. 182: 24-32. PMID 142445 DOI: 10.1016/0003-9861(77)90279-X  0.107
2022 Solaro RJ. Advances in understanding the state of titin truncation variants in dilated cardiomyopathy. Pflugers Archiv : European Journal of Physiology. 474: 265-266. PMID 35020065 DOI: 10.1007/s00424-022-02664-0  0.105
1981 Shiner JS, Solaro RJ. The effects of modifiers on enzyme catalysis: a non-classical nearest neighbor approach. Biophysical Chemistry. 13: 291-306. PMID 7284559 DOI: 10.1016/0301-4622(81)85003-X  0.1
2018 Felice F, Piras AM, Rocchiccioli S, Barsotti MC, Santoni T, Pucci A, Burchielli S, Chiellini F, Ucciferri N, Solaro R, Altomare A, Cecchettini A, Di Stefano R. Endothelial progenitor cell secretome delivered by novel polymeric nanoparticles in ischemic hindlimb. International Journal of Pharmaceutics. 542: 82-89. PMID 29526620 DOI: 10.1016/j.ijpharm.2018.03.015  0.092
1979 Litten RZ, Solaro RJ, Ford GD. Nature of the calcium regulatory system of bovine arterial actomyosin Journal of Vascular Research. 16: 26-34. DOI: 10.1159/000158187  0.089
1979 Litten RZ, Solaro RJ, Ford GD. Nature of the calcium regulatory system of bovine arterial actomyosin. Blood Vessels. 16: 26-34. PMID 153774 DOI: 10.1159/000158187  0.086
1969 Buckley JP, Solaro RJ, Barry H. Effects of phenformin HC1 on rats subjected to simulated high altitude Journal of Pharmaceutical Sciences. 58: 348-351. PMID 5782030 DOI: 10.1002/Jps.2600580313  0.085
1978 Solaro RJ, Gleason EN. Effect of cross bridge connections on cation selectivity of myofibrillar troponin C Circulation. 58.  0.077
1997 Miertus S, Tomasi J, Mazzanti G, Chiellini EE, Solaro R, Chiellini E. Modelling of the 3-D structure of IFN-alpha-k and characterization of its surface molecular properties. International Journal of Biological Macromolecules. 20: 85-95. PMID 9184940 DOI: 10.1016/s0141-8130(96)01143-9  0.077
1996 Chiellini E, Solaro R, Bemporad L, D'Antone S, Giannasi D, Leonardi G. New hydrophilic polyesters and related polymers as bioerodible polymeric matrices. Journal of Biomaterials Science. Polymer Edition. 7: 307-28. PMID 7495762 DOI: 10.1163/156856295x00346  0.076
2008 Bertinetto C, Duce C, Micheli A, Solaro R, Starita A, Tiné MR. Evaluation of hierarchical structured representations for QSPR studies of small molecules and polymers by recursive neural networks. Journal of Molecular Graphics & Modelling. 27: 797-802. PMID 19150251 DOI: 10.1016/j.jmgm.2008.12.001  0.074
2007 Duce C, Monti S, Solaro R, Tiné MR. Ionic peptide aggregation: exploration of conformational dynamics in aqueous solution by computational techniques. The Journal of Physical Chemistry. B. 111: 1165-75. PMID 17266271 DOI: 10.1021/jp066307n  0.071
2003 Bizzarri R, Cerbai B, Signori F, Solaro R, Bergamini E, Tamburini I, Chiellini E. New perspectives for (S)-dolichol and (S)- nor dolichol synthesis and biological functions. Biogerontology. 4: 353-63. PMID 14739706 DOI: 10.1023/B:BGEN.0000006555.87407.04  0.067
2004 Towbin JA, Solaro RJ. Genetics of dilated cardiomyopathy: More genes that kill Journal of the American College of Cardiology. 44: 2041-2043. PMID 15542289 DOI: 10.1016/j.jacc.2004.08.028  0.063
2008 Alderighi M, Ierardi V, Allegrini M, Fuso F, Solaro R. An atomic force microscopy tip model for investigating the mechanical properties of materials at the nanoscale. Journal of Nanoscience and Nanotechnology. 8: 2479-82. PMID 18572668 DOI: 10.1166/jnn.2008.360  0.063
2011 Barsotti MC, Magera A, Armani C, Chiellini F, Felice F, Dinucci D, Piras AM, Minnocci A, Solaro R, Soldani G, Balbarini A, Di Stefano R. Fibrin acts as biomimetic niche inducing both differentiation and stem cell marker expression of early human endothelial progenitor cells. Cell Proliferation. 44: 33-48. PMID 21199008 DOI: 10.1111/j.1365-2184.2010.00715.x  0.063
2009 Alderighi M, Ierardi V, Fuso F, Allegrini M, Solaro R. Size effects in nanoindentation of hard and soft surfaces. Nanotechnology. 20: 235703. PMID 19451684 DOI: 10.1088/0957-4484/20/23/235703  0.062
2012 Bartolozzi I, Solaro R, Mari G, Bonaguidi P, Chiellini E. Removal of viruscide agents by using styrenic resins. Journal of Applied Biomaterials & Biomechanics : Jabb. 2: 105-11. PMID 20803444  0.062
2010 Ankola DD, Battisti A, Solaro R, Kumar MN. Nanoparticles made of multi-block copolymer of lactic acid and ethylene glycol containing periodic side-chain carboxyl groups for oral delivery of cyclosporine A. Journal of the Royal Society, Interface. S475-81. PMID 20504806 DOI: 10.1098/rsif.2010.0046.focus  0.061
2009 Ierardi V, Niccolini A, Alderighi M, Gazzano A, Martelli F, Solaro R. AFM characterization of rabbit spermatozoa. Microscopy Research and Technique. 71: 529-35. PMID 18393303 DOI: 10.1002/jemt.20584  0.055
1996 Wernberg G, Gentry JM, Solaro RJ. Association of Chairmen of Departments of Physiology 1995 survey results The Physiologist.. 39: 83-89. PMID 16764117  0.052
2010 Bertinetto CG, Duce C, Micheli A, Solaro R, Tiné MR. QSPR Analysis of Copolymers by Recursive Neural Networks: Prediction of the Glass Transition Temperature of (Meth)acrylic Random Copolymers. Molecular Informatics. 29: 635-43. PMID 27463457 DOI: 10.1002/minf.201000079  0.05
2005 Corti A, Frassinetti S, Vallini G, D'Antone S, Fichi C, Solaro R. Biodegradation of nonionic surfactants. I. Biotransformation of 4-(1-nonyl)phenol by a Candida maltosa isolate. Environmental Pollution (Barking, Essex : 1987). 90: 83-7. PMID 15091504 DOI: 10.1016/0269-7491(94)00080-w  0.049
2005 Solaro R, Chiellini F, Signori F, Fiumi C, Bizzarri R, Chiellini E. Nanoparticle systems for the targeted release of active principles of proteic nature. Journal of Materials Science. Materials in Medicine. 14: 705-11. PMID 15348412 DOI: 10.1023/a:1024963700223  0.041
2006 Chiellini EE, Chiellini F, Solaro R. Bioerodible polymeric nanoparticles for targeted delivery of proteic drugs. Journal of Nanoscience and Nanotechnology. 6: 3040-7. PMID 17048516 DOI: 10.1166/jnn.2006.412  0.039
2005 Signori F, Solaro R, Chiellini E. Micelles from new biodegradable amphiphilic block copolymers containing PEG AND PCL. Journal of Controlled Release : Official Journal of the Controlled Release Society. 101: 379-81. PMID 15822224  0.024
1989 Just H, Solaro RJ. Introduction Journal of Cardiovascular Pharmacology. 14: v-vii.  0.02
2014 Tzvetanov I, West-Thielke P, D'Amico G, Johnsen M, Ladik A, Hachaj G, Grazman M, Heller RU, Fernhall B, Daviglus ML, Solaro RJ, Oberholzer J, Gallon L, Benedetti E. A novel and personalized rehabilitation program for obese kidney transplant recipients. Transplantation Proceedings. 46: 3431-7. PMID 25498067 DOI: 10.1016/j.transproceed.2014.05.085  0.016
2007 Bartolozzi I, Solaro R, Chiellini E, Schacht EH, Ranucci E. Amphiphilic block copolymers containing poly(vinylpyrrolidone) and poly(caprolactone). Journal of Controlled Release : Official Journal of the Controlled Release Society. 116: e15-7. PMID 17718946 DOI: 10.1016/J.JCONREL.2006.09.026  0.011
Hide low-probability matches.