Frank A. Simmen - Publications

Physiology and Biophysics University of Arkansas for Medical Sciences, United States 
Oncology, General

135 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Simmen FA, Alhallak I, Simmen RCM. Malic enzyme 1 (ME1) in the biology of cancer: it is not just intermediary metabolism. Journal of Molecular Endocrinology. 65: R77-R90. PMID 33064660 DOI: 10.1530/Jme-20-0176  0.4
2020 Pabona JMP, Burnett AF, Brown DM, Quick CM, Simmen FA, Montales MTE, Liu SJ, Rose T, Alhallak I, Siegel ER, Simmen RC. Metformin Promotes Anti-tumor Biomarkers in Human Endometrial Cancer Cells. Reproductive Sciences (Thousand Oaks, Calif.). PMID 32046384 DOI: 10.1007/S43032-019-00019-2  0.4
2018 Fernandes LM, Al-Dwairi A, Simmen RCM, Marji M, Brown DM, Jewell SW, Simmen FA. Malic Enzyme 1 (ME1) is pro-oncogenic in Apc mice. Scientific Reports. 8: 14268. PMID 30250042 DOI: 10.1038/S41598-018-32532-W  0.4
2018 Brown DM, Lee HC, Liu S, Quick CM, Fernandes LM, Simmen FA, Tsai SJ, Simmen RCM. Notch-1 Signaling Activation and Progesterone Receptor Expression in Ectopic Lesions of Women With Endometriosis. Journal of the Endocrine Society. 2: 765-778. PMID 30151432 DOI: 10.1210/Js.2018-00007  0.4
2016 Yu S, Wu X, Ferguson M, Simmen RC, Cleves MA, Simmen FA, Fang N. Diets Containing Shiitake Mushroom Reduce Serum Lipids and Serum Lipophilic Antioxidant Capacity in Rats. The Journal of Nutrition. PMID 27798348 DOI: 10.3945/Jn.116.239806  0.44
2016 Heard ME, Melnyk SB, Simmen FA, Yang Y, Pabona JM, Simmen RC. High-Fat Diet Promotion of Endometriosis in an Immunocompetent Mouse Model is Associated with Altered Peripheral and Ectopic Lesion Redox and Inflammatory Status. Endocrinology. en20161092. PMID 27175969 DOI: 10.1210/En.2016-1092  0.52
2015 Montales MT, Simmen RC, Ferreira ES, Neves VA, Simmen FA. Metformin and soybean-derived bioactive molecules attenuate the expansion of stem cell-like epithelial subpopulation and confer apoptotic sensitivity in human colon cancer cells. Genes & Nutrition. 10: 49. PMID 26506839 DOI: 10.1007/S12263-015-0499-6  0.52
2015 Brown AR, Simmen RC, Raj VR, Van TT, MacLeod SL, Simmen FA. Krüppel-like Factor 9 (KLF9) prevents colorectal cancer through inhibition of interferon-related signaling. Carcinogenesis. PMID 26210742 DOI: 10.1093/Carcin/Bgv104  0.52
2015 Heard ME, Velarde MC, Giudice LC, Simmen FA, Simmen RC. Krüppel-Like Factor 13 Deficiency in Uterine Endometrial Cells Contributes to Defective Steroid Hormone Receptor Signaling but Not Lesion Establishment in a Mouse Model of Endometriosis. Biology of Reproduction. 92: 140. PMID 25904015 DOI: 10.1095/Biolreprod.115.130260  0.52
2015 Pabona JM, Zhang D, Ginsburg DS, Simmen FA, Simmen RC. Prolonged pregnancy in women is associated with attenuated myometrial expression of progesterone receptor co-regulator Krüppel-like Factor 9. The Journal of Clinical Endocrinology and Metabolism. 100: 166-74. PMID 25313913 DOI: 10.1210/Jc.2014-2846  0.52
2015 Pabona JMP, Zhang D, Ginsburg DS, Simmen FA, Simmen RCM. Prolonged pregnancy in women is associated with attenuated myometrial expression of progesterone receptor co regulator krüppel like factor 9 Journal of Clinical Endocrinology and Metabolism. 100: 166-174. DOI: 10.1210/jc.20142846  0.52
2014 Al-Dwairi A, Brown AR, Pabona JM, Van TH, Hamdan H, Mercado CP, Quick CM, Wight PA, Simmen RC, Simmen FA. Enhanced gastrointestinal expression of cytosolic malic enzyme (ME1) induces intestinal and liver lipogenic gene expression and intestinal cell proliferation in mice. Plos One. 9: e113058. PMID 25402228 DOI: 10.1371/Journal.Pone.0113058  0.52
2014 Montales MT, Melnyk SB, Simmen FA, Simmen RC. Maternal metabolic perturbations elicited by high-fat diet promote Wnt-1-induced mammary tumor risk in adult female offspring via long-term effects on mammary and systemic phenotypes. Carcinogenesis. 35: 2102-12. PMID 24832086 DOI: 10.1093/Carcin/Bgu106  0.52
2014 Heard ME, Simmons CD, Simmen FA, Simmen RC. Krüppel-like factor 9 deficiency in uterine endometrial cells promotes ectopic lesion establishment associated with activated notch and hedgehog signaling in a mouse model of endometriosis. Endocrinology. 155: 1532-46. PMID 24476135 DOI: 10.1210/En.2013-1947  0.52
2013 Brown AR, Simmen RC, Simmen FA. The role of thyroid hormone signaling in the prevention of digestive system cancers. International Journal of Molecular Sciences. 14: 16240-57. PMID 23924944 DOI: 10.3390/Ijms140816240  0.52
2013 Rahal OM, Pabona JM, Kelly T, Huang Y, Hennings LJ, Prior RL, Al-Dwairi A, Simmen FA, Simmen RC. Suppression of Wnt1-induced mammary tumor growth and lower serum insulin in offspring exposed to maternal blueberry diet suggest early dietary influence on developmental programming. Carcinogenesis. 34: 464-74. PMID 23144318 DOI: 10.1093/Carcin/Bgs353  0.52
2012 Al-Dwairi A, Pabona JM, Simmen RC, Simmen FA. Cytosolic malic enzyme 1 (ME1) mediates high fat diet-induced adiposity, endocrine profile, and gastrointestinal tract proliferation-associated biomarkers in male mice. Plos One. 7: e46716. PMID 23056418 DOI: 10.1371/Journal.Pone.0046716  0.52
2012 Heard ME, Pabona JM, Clayberger C, Krensky AM, Simmen FA, Simmen RC. The reproductive phenotype of mice null for transcription factor Krüppel-like factor 13 suggests compensatory function of family member Krüppel-like factor 9 in the peri-implantation uterus. Biology of Reproduction. 87: 115. PMID 22993382 DOI: 10.1095/Biolreprod.112.102251  0.52
2012 Hakkak R, Al-Dwairi A, Fuchs GJ, Korourian S, Simmen FA. Dietary soy protein induces hepatic lipogenic enzyme gene expression while suppressing hepatosteatosis in obese female Zucker rats bearing DMBA-initiated mammary tumors. Genes & Nutrition. 7: 549-58. PMID 22528625 DOI: 10.1007/S12263-012-0294-6  0.52
2012 Pabona JM, Simmen FA, Nikiforov MA, Zhuang D, Shankar K, Velarde MC, Zelenko Z, Giudice LC, Simmen RC. Krüppel-like factor 9 and progesterone receptor coregulation of decidualizing endometrial stromal cells: implications for the pathogenesis of endometriosis. The Journal of Clinical Endocrinology and Metabolism. 97: E376-92. PMID 22259059 DOI: 10.1210/Jc.2011-2562  0.52
2011 Simmen FA, Simmen RC. The maternal womb: a novel target for cancer prevention in the era of the obesity pandemic? European Journal of Cancer Prevention : the Official Journal of the European Cancer Prevention Organisation (Ecp). 20: 539-48. PMID 21701386 DOI: 10.1097/Cej.0B013E328348Fc21  0.52
2011 Simmons CD, Pabona JM, Heard ME, Friedman TM, Spataro MT, Godley AL, Simmen FA, Burnett AF, Simmen RC. Krüppel-like factor 9 loss-of-expression in human endometrial carcinoma links altered expression of growth-regulatory genes with aberrant proliferative response to estrogen. Biology of Reproduction. 85: 378-85. PMID 21543766 DOI: 10.1095/Biolreprod.110.090654  0.52
2010 Pabona JM, Zeng Z, Simmen FA, Simmen RC. Functional differentiation of uterine stromal cells involves cross-regulation between bone morphogenetic protein 2 and Kruppel-like factor (KLF) family members KLF9 and KLF13. Endocrinology. 151: 3396-406. PMID 20410205 DOI: 10.1210/En.2009-1370  0.52
2010 Simmons CD, Pabona JM, Zeng Z, Velarde MC, Gaddy D, Simmen FA, Simmen RC. Response of adult mouse uterus to early disruption of estrogen receptor-alpha signaling is influenced by Krüppel-like factor 9. The Journal of Endocrinology. 205: 147-57. PMID 20164373 DOI: 10.1677/Joe-09-0474  0.52
2010 Simmen FA, Mercado CP, Zavacki AM, Huang SA, Greenway AD, Kang P, Bowman MT, Prior RL. Soy protein diet alters expression of hepatic genes regulating fatty acid and thyroid hormone metabolism in the male rat. The Journal of Nutritional Biochemistry. 21: 1106-13. PMID 19962299 DOI: 10.1016/J.Jnutbio.2009.09.008  0.52
2010 Simmen RC, Pabona JM, Velarde MC, Simmons C, Rahal O, Simmen FA. The emerging role of Krüppel-like factors in endocrine-responsive cancers of female reproductive tissues. The Journal of Endocrinology. 204: 223-31. PMID 19833720 DOI: 10.1677/Joe-09-0329  0.52
2009 Simmen FA, Frank JA, Wu X, Xiao R, Hennings LJ, Prior RL. Lack of efficacy of blueberry in nutritional prevention of azoxymethane-initiated cancers of rat small intestine and colon. Bmc Gastroenterology. 9: 67. PMID 19758446 DOI: 10.1186/1471-230X-9-67  0.52
2009 Pabona JM, Velarde MC, Zeng Z, Simmen FA, Simmen RC. Nuclear receptor co-regulator Krüppel-like factor 9 and prohibitin 2 expression in estrogen-induced epithelial cell proliferation in the mouse uterus. The Journal of Endocrinology. 200: 63-73. PMID 18835980 DOI: 10.1677/Joe-08-0383  0.52
2008 Simmen FA, Su Y, Xiao R, Zeng Z, Simmen RC. The Krüppel-like factor 9 (KLF9) network in HEC-1-A endometrial carcinoma cells suggests the carcinogenic potential of dys-regulated KLF9 expression. Reproductive Biology and Endocrinology : Rb&E. 6: 41. PMID 18783612 DOI: 10.1186/1477-7827-6-41  0.52
2008 Zeng Z, Velarde MC, Simmen FA, Simmen RC. Delayed parturition and altered myometrial progesterone receptor isoform A expression in mice null for Krüppel-like factor 9. Biology of Reproduction. 78: 1029-37. PMID 18305227 DOI: 10.1095/Biolreprod.107.065821  0.52
2008 Xiao R, Su Y, Simmen RC, Simmen FA. Dietary soy protein inhibits DNA damage and cell survival of colon epithelial cells through attenuated expression of fatty acid synthase. American Journal of Physiology. Gastrointestinal and Liver Physiology. 294: G868-76. PMID 18239060 DOI: 10.1152/Ajpgi.00515.2007  0.52
2007 Xiao R, Hennings LJ, Badger TM, Simmen FA. Fetal programming of colon cancer in adult rats: correlations with altered neonatal growth trajectory, circulating IGF-I and IGF binding proteins, and testosterone. The Journal of Endocrinology. 195: 79-87. PMID 17911399 DOI: 10.1677/Joe-07-0256  0.52
2007 Velarde MC, Zeng Z, McQuown JR, Simmen FA, Simmen RC. Kruppel-like factor 9 is a negative regulator of ligand-dependent estrogen receptor alpha signaling in Ishikawa endometrial adenocarcinoma cells. Molecular Endocrinology (Baltimore, Md.). 21: 2988-3001. PMID 17717078 DOI: 10.1210/Me.2007-0242  0.52
2007 He L, Marecki JC, Serrero G, Simmen FA, Ronis MJ, Badger TM. Dose-dependent effects of alcohol on insulin signaling: partial explanation for biphasic alcohol impact on human health. Molecular Endocrinology (Baltimore, Md.). 21: 2541-50. PMID 17622585 DOI: 10.1210/Me.2007-0036  0.52
2007 Simmen FA, Xiao R, Velarde MC, Nicholson RD, Bowman MT, Fujii-Kuriyama Y, Oh SP, Simmen RC. Dysregulation of intestinal crypt cell proliferation and villus cell migration in mice lacking Kruppel-like factor 9. American Journal of Physiology. Gastrointestinal and Liver Physiology. 292: G1757-69. PMID 17379758 DOI: 10.1152/Ajpgi.00013.2007  0.52
2007 Su Y, Simmen FA, Xiao R, Simmen RC. Expression profiling of rat mammary epithelial cells reveals candidate signaling pathways in dietary protection from mammary tumors. Physiological Genomics. 30: 8-16. PMID 17341692 DOI: 10.1152/Physiolgenomics.00023.2007  0.52
2006 Eason RR, Till SR, Frank JA, Badger TM, Korourian S, Simmen FA, Simmen RC. Tumor-protective and tumor-promoting actions of dietary whey proteins in an N-methyl-N-nitrosourea model of rat mammary carcinogenesis. Nutrition and Cancer. 55: 171-7. PMID 17044772 DOI: 10.1207/S15327914Nc5502_8  0.52
2006 Shankar K, Hidestrand M, Liu X, Xiao R, Skinner CM, Simmen FA, Badger TM, Ronis MJ. Physiologic and genomic analyses of nutrition-ethanol interactions during gestation: Implications for fetal ethanol toxicity. Experimental Biology and Medicine (Maywood, N.J.). 231: 1379-97. PMID 16946407 DOI: 10.1177/153537020623100812  0.52
2006 Xiao R, Carter JA, Linz AL, Ferguson M, Badger TM, Simmen FA. Dietary whey protein lowers serum C-peptide concentration and duodenal SREBP-1c mRNA abundance, and reduces occurrence of duodenal tumors and colon aberrant crypt foci in azoxymethane-treated male rats. The Journal of Nutritional Biochemistry. 17: 626-34. PMID 16504496 DOI: 10.1016/J.Jnutbio.2005.11.008  0.52
2006 Simmen FA, Simmen RC. Orchestrating the menstrual cycle: discerning the music from the noise. Endocrinology. 147: 1094-6. PMID 16481481 DOI: 10.1210/En.2005-1451  0.52
2006 He L, Simmen FA, Mehendale HM, Ronis MJ, Badger TM. Chronic ethanol intake impairs insulin signaling in rats by disrupting Akt association with the cell membrane. Role of TRB3 in inhibition of Akt/protein kinase B activation. The Journal of Biological Chemistry. 281: 11126-34. PMID 16452480 DOI: 10.1074/Jbc.M510724200  0.52
2006 Kwak I, Song S, Blum JL, Simmen RC, Simmen FA. Enhancer- and silencer-like sequences that mediate insulin-like growth factor-binding protein-2 gene expression in uterine cells of pregnancy. Dna and Cell Biology. 25: 6-18. PMID 16405396 DOI: 10.1089/Dna.2006.25.6  0.52
2006 Velarde MC, Iruthayanathan M, Eason RR, Zhang D, Simmen FA, Simmen RC. Progesterone receptor transactivation of the secretory leukocyte protease inhibitor gene in Ishikawa endometrial epithelial cells involves recruitment of Krüppel-like factor 9/basic transcription element binding protein-1. Endocrinology. 147: 1969-78. PMID 16384861 DOI: 10.1210/En.2005-1419  0.52
2006 Frank JA, Xiao R, Yu S, Ferguson M, Hennings LJ, Simpson PM, Ronis MJJ, Fang N, Badger TM, Simmen FA. Effect of Shiitake mushroom dose on colon tumorigenesis in azoxymethane-treated male Sprague-Dawley rats Nutrition Research. 26: 138-145. DOI: 10.1016/J.Nutres.2006.03.001  0.52
2005 Eason RR, Till SR, Velarde MC, Geng Y, Chatman L, Gu L, Badger TM, Simmen FA, Simmen RC. Uterine phenotype of young adult rats exposed to dietary soy or genistein during development. The Journal of Nutritional Biochemistry. 16: 625-32. PMID 16081271 DOI: 10.1016/J.Jnutbio.2005.03.005  0.52
2005 Velarde MC, Geng Y, Eason RR, Simmen FA, Simmen RC. Null mutation of Kruppel-like factor9/basic transcription element binding protein-1 alters peri-implantation uterine development in mice. Biology of Reproduction. 73: 472-81. PMID 15917344 DOI: 10.1095/Biolreprod.105.041855  0.52
2005 Badger TM, Ronis MJ, Simmen RC, Simmen FA. Soy protein isolate and protection against cancer. Journal of the American College of Nutrition. 24: 146S-149S. PMID 15798082 DOI: 10.1080/07315724.2005.10719456  0.52
2005 Xiao R, Badger TM, Simmen FA. Dietary exposure to soy or whey proteins alters colonic global gene expression profiles during rat colon tumorigenesis. Molecular Cancer. 4: 1. PMID 15644144 DOI: 10.1186/1476-4598-4-1  0.52
2005 Velarde MC, Parisek SI, Eason RR, Simmen FA, Simmen RC. The secretory leukocyte protease inhibitor gene is a target of epidermal growth factor receptor action in endometrial epithelial cells. The Journal of Endocrinology. 184: 141-51. PMID 15642791 DOI: 10.1677/Joe.1.05800  0.52
2004 Linz AL, Xiao R, Parker JG, Simpson PM, Badger TM, Simmen FA. Feeding of soy protein isolate to rats during pregnancy and lactation suppresses formation of aberrant crypt foci in their progeny's colons: interaction of diet with fetal alcohol exposure. Journal of Carcinogenesis. 3: 14. PMID 15488141 DOI: 10.1186/1477-3163-3-14  0.52
2004 Gaucher EA, Graddy LG, Li T, Simmen RC, Simmen FA, Schreiber DR, Liberles DA, Janis CM, Benner SA. The planetary biology of cytochrome P450 aromatases. Bmc Biology. 2: 19. PMID 15315709 DOI: 10.1186/1741-7007-2-19  0.52
2004 He L, Simmen FA, Ronis MJ, Badger TM. Post-transcriptional regulation of sterol regulatory element-binding protein-1 by ethanol induces class I alcohol dehydrogenase in rat liver. The Journal of Biological Chemistry. 279: 28113-21. PMID 15123720 DOI: 10.1074/Jbc.M400906200  0.52
2004 Simmen RC, Eason RR, McQuown JR, Linz AL, Kang TJ, Chatman L, Till SR, Fujii-Kuriyama Y, Simmen FA, Oh SP. Subfertility, uterine hypoplasia, and partial progesterone resistance in mice lacking the Kruppel-like factor 9/basic transcription element-binding protein-1 (Bteb1) gene. The Journal of Biological Chemistry. 279: 29286-94. PMID 15117941 DOI: 10.1074/Jbc.M403139200  0.52
2004 Kowalski AA, Vale-Cruz DS, Simmen FA, Simmen RC. Uterine androgen receptors: roles in estrogen-mediated gene expressionand DNA synthesis. Biology of Reproduction. 70: 1349-57. PMID 14711790 DOI: 10.1095/Biolreprod.103.024786  0.52
2003 Zhang XL, Zhang D, Michel FJ, Blum JL, Simmen FA, Simmen RC. Selective interactions of Kruppel-like factor 9/basic transcription element-binding protein with progesterone receptor isoforms A and B determine transcriptional activity of progesterone-responsive genes in endometrial epithelial cells. The Journal of Biological Chemistry. 278: 21474-82. PMID 12672823 DOI: 10.1074/Jbc.M212098200  0.52
2002 Hausman GJ, Richardson RL, Simmen FA. Secretion of insulin-like growth factor (IGF)-I and -II and IGF binding proteins (IGFBPs) in fetal stromal-vascular (S-V) cell cultures obtained before and after the onset of adipogenesis in vivo Growth, Development and Aging. 66: 11-26. PMID 2002139871  0.52
2002 Macpherson ML, Simmen RC, Simmen FA, Hernandez J, Sheerin BR, Varner DD, Loomis P, Cadario ME, Miller CD, Brinsko SP, Rigby S, Blanchard TL. Insulin-like growth factor-I and insulin-like growth factor binding protein-2 and -5 in equine seminal plasma: association with sperm characteristics and fertility. Biology of Reproduction. 67: 648-54. PMID 12135910 DOI: 10.1095/Biolreprod67.2.648  0.52
2002 Simmen RC, Simmen FA. Progesterone receptors and Sp/Krüppel-like family members in the uterine endometrium . Frontiers in Bioscience : a Journal and Virtual Library. 7: d1556-65. PMID 12045021 DOI: 10.2741/Simmen  0.52
2002 Zhang D, Simmen RC, Michel FJ, Zhao G, Vale-Cruz D, Simmen FA. Secretory leukocyte protease inhibitor mediates proliferation of human endometrial epithelial cells by positive and negative regulation of growth-associated genes. The Journal of Biological Chemistry. 277: 29999-30009. PMID 12023969 DOI: 10.1074/Jbc.M203503200  0.52
2002 Simmen RC, Zhang XL, Michel FJ, Min SH, Zhao G, Simmen FA. Molecular markers of endometrial epithelial cell mitogenesis mediated by the Sp/Krüppel-like factor BTEB1. Dna and Cell Biology. 21: 115-28. PMID 11953011 DOI: 10.1089/104454902753604998  0.52
2002 Kowalski AA, Graddy LG, Vale-Cruz DS, Choi I, Katzenellenbogen BS, Simmen FA, Simmen RC. Molecular cloning of porcine estrogen receptor-beta complementary DNAs and developmental expression in periimplantation embryos. Biology of Reproduction. 66: 760-9. PMID 11870084 DOI: 10.1095/Biolreprod66.3.760  0.52
2002 Zhang D, Zhang XL, Michel FJ, Blum JL, Simmen FA, Simmen RC. Direct interaction of the Krüppel-like family (KLF) member, BTEB1, and PR mediates progesterone-responsive gene expression in endometrial epithelial cells. Endocrinology. 143: 62-73. PMID 11751593 DOI: 10.1210/Endo.143.1.8590  0.52
2002 Min SH, Simmen RCM, Alhonen L, Halmekytö M, Porter CW, Jänne J, Simmen FA. Altered levels of growth-related and novel gene transcripts in reproductive and other tissues of female mice overexpressing spermidine/spermine N1-acetyltransferase (SSAT) Journal of Biological Chemistry. 277: 3647-3657. PMID 11709547 DOI: 10.1074/Jbc.M100751200  0.52
2001 Zhang XL, Simmen FA, Michel FJ, Simmen RCM. Increased expression of the Zn-finger transcription factor BTEB1 in human endometrial cells is correlated with distinct cell phenotype, gene expression patterns, and proliferative responsiveness to serum and TGF-β1 Molecular and Cellular Endocrinology. 181: 81-96. PMID 11476943 DOI: 10.1016/S0303-7207(01)00536-6  0.52
2001 Rodriguez-Sallaberry C, Simmen FA, Simmen RCM. Polyamine- and insulin-like growth factor-I-mediated proliferation of porcine uterine endometrial cells: A potential role for spermidine/spermine N1-acetyltransferase during peri-implantation Biology of Reproduction. 65: 587-594. PMID 11466230 DOI: 10.1095/Biolreprod65.2.587  0.52
2001 Smith TPL, Fahrenkrug SC, Rohrer GA, Simmen FA, Rexroad CE, Keele JW. Mapping of expressed sequence tags from a porcine early embryonic cDNA library Animal Genetics. 32: 66-72. PMID 11421940 DOI: 10.1046/J.1365-2052.2001.00739.X  0.52
2001 Lee CY, Kwak I, Chung CS, Choi WS, Simmen RC, Simmen FA. Molecular cloning of the porcine acid-labile subunit (ALS) of the insulin-like growth factor-binding protein complex and detection of ALS gene expression in hepatic and non-hepatic tissues. Journal of Molecular Endocrinology. 26: 135-44. PMID 11241165 DOI: 10.1677/Jme.0.0260135  0.52
2001 Smith TPL, Simmen FA, Zhao G, Vallet JL. Rapid communication: Nucleotide sequences of two informs of porcine micromolar calcium-activated neutral protease 1 cDNA Journal of Animal Science. 79: 552-553. PMID 11219468 DOI: 10.2527/2001.792552X  0.52
2000 Kao YC, Higashiyama T, Sun X, Okubo T, Yarborough C, Choi I, Osawa Y, Simmen FA, Chen S. Catalytic differences between porcine blastocyst and placental aromatase isozymes. European Journal of Biochemistry / Febs. 267: 6134-9. PMID 11012665 DOI: 10.1046/J.1432-1327.2000.01705.X  0.52
2000 Hausman GJ, Richardson RL, Simmen FA. Expression of insulin-like growth factor binding proteins (IGFBPs) before and during the hormone sensitive period of adipose tissue development in the fetal pig Growth, Development and Aging. 64: 51-67. PMID 10969885  0.52
2000 Wandji SA, Gadsby JE, Simmen FA, Barber JA, Hammond JM. Porcine ovarian cells express messenger ribonucleic acids for the acid-labile subunit and insulin-like growth factor binding protein-3 during follicular and luteal phases of the estrous cycle Endocrinology. 141: 2638-2647. PMID 10875269 DOI: 10.1210/Endo.141.7.7563  0.52
2000 Modric T, Kowalski AA, Green ML, Simmen RC, Simmen FA. Pregnancy-dependent expression of leukaemia inhibitory factor (LIF), LIF receptor-beta and interleukin-6 (IL-6) messenger ribonucleic acids in the porcine female reproductive tract. Placenta. 21: 345-53. PMID 10833369 DOI: 10.1053/Plac.1999.0493  0.52
2000 Graddy LG, Kowalski AA, Simmen FA, Davis SLF, Baumgartner WW, Simmen RCM. Multiple isoforms of porcine aromatase are encoded by three distinct genes Journal of Steroid Biochemistry and Molecular Biology. 73: 49-57. PMID 10822024 DOI: 10.1016/S0960-0760(00)00054-6  0.52
2000 Simmen RCM, Zhang XL, Zhang D, Wang Y, Michel FJ, Simmen FA. Expression and regulatory function of the transcription factor Sp1 in the uterine endometrium at early pregnancy: Implications for epithelial phenotype Molecular and Cellular Endocrinology. 159: 159-170. PMID 10687861 DOI: 10.1016/S0303-7207(99)00191-4  0.52
1999 Badinga L, Song S, Simmen RCM, Clarke JB, Clemmons DR, Simmen FA. Complex mediation of uterine endometrial epithelial cell growth by insulin-like growth factor-II (IGF-II) and IGF-binding protein-2 Journal of Molecular Endocrinology. 23: 277-285. PMID 10601973 DOI: 10.1677/Jme.0.0230277  0.52
1999 Simmen RCM, Chung TE, Imataka H, Michel FJ, Badinga L, Simmen FA. Trans-activation functions of the Sp-related nuclear factor, basic transcription element-binding protein, and progesterone receptor in endometrial epithelial cells Endocrinology. 140: 2517-2525. PMID 10342837 DOI: 10.1210/Endo.140.6.6625  0.52
1999 Severgnini S, Lowenthal DT, Millard WJ, Simmen FA, Pollock BH, Borst SE. Altered IGF-I and IGFBPs in senescent male and female rats. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. 54: B111-5. PMID 10191834 DOI: 10.1093/Gerona/54.3.B111  0.52
1998 Green ML, Chung TE, Reed KL, Modric T, Badinga L, Yang J, Simmen FA, Simmen RCM. Paracrine inducers of uterine endometrial spermidine/spermine N1- acetyltransferase gene expression during early pregnancy in the pig Biology of Reproduction. 59: 1251-1258. PMID 9780334 DOI: 10.1095/Biolreprod59.5.1251  0.52
1998 Badinga L, Song S, Simmen RCM, Simmen FA. A distal regulatory region of the insulin-like growth factor binding protein-2 (IGFBP-2) gene interacts with the basic helix-loop-helix transcription factor, AP-4 Endocrine. 8: 281-289. PMID 9741833 DOI: 10.1385/Endo:8:3:281  0.52
1998 Lee CY, Green ML, Simmen RCM, Simmen FA. Proteolysis of insulin-like growth factor-binding proteins (IGFBPs) within the pig uterine lumen associated with peri-implantation conceptus development Journal of Reproduction and Fertility. 112: 369-377. PMID 9640276 DOI: 10.1530/Jrf.0.1120369  0.52
1998 Simmen FA, Badinga L, Green ML, Kwak I, Song S, Simmen RCM. The porcine insulin-like growth factor system: At the interface of nutrition, growth and reproduction Journal of Nutrition. 128. PMID 9478014 DOI: 10.1093/Jn/128.2.315S  0.52
1998 Richardson RL, Hausman GJ, Simmen FA. Neutralization of Insulin-like Growth Factor-Binding Protein-2 (IGFBP-2) in serum-free cultures of porcine stromal-vascular cells increases adipocyte differentiation Faseb Journal. 12.  0.52
1997 Wang Y, Michel FJ, Wing A, Simmen FA, Simmen RCM. Cell-type expression, immunolocalization, and deoxyribonucleic acid- binding activity of basic transcription element binding transcription factor, an Sp-related family member, in porcine endometrium of pregnancy Biology of Reproduction. 57: 707-714. PMID 9314570 DOI: 10.1095/Biolreprod57.4.707  0.52
1997 Choi I, Collante WR, Simmen RCM, Simmen FA. A developmental switch in expression from blastocyst to endometrial/placental-type cytochrome P450 aromatase genes in the pig and horse Biology of Reproduction. 56: 688-696. PMID 9047015 DOI: 10.1095/Biolreprod56.3.688  0.52
1996 Buhi WC, Alvarez IM, Choi I, Cleaver BD, Simmen FA. Molecular cloning and characterization of an estrogen-dependent porcine oviductal secretory glycoprotein Biology of Reproduction. 55: 1305-1314. PMID 8949888 DOI: 10.1095/Biolreprod55.6.1305  0.52
1996 Green ML, Blaeser LL, Simmen FA, Simmen RCM. Molecular Cloning of Spermidine/Spermine N1-Acetyltransferase from the Periimplantation Porcine Uterus by Messenger Ribonucleic Acid Differential Display: Temporal and Conceptus-Modulated Gene Expression Endocrinology. 137: 5447-5455. PMID 8940370 DOI: 10.1210/Endo.137.12.8940370  0.52
1996 Kirby CJ, Thatcher WW, Collier RJ, Simmen FA, Lucy MC. Effects of growth hormone and pregnancy on expression of growth hormone receptor, insulin-like growth factor-I, and insulin-like growth factor binding protein-2 and -3 genes in bovine uterus, ovary, and oviduct. Biology of Reproduction. 55: 996-1002. PMID 8902209 DOI: 10.1095/Biolreprod55.5.996  0.52
1996 Samaras SE, Canning SF, Barber JA, Simmen FA, Hammond JM. Regulation of insulin-like growth factor I biosynthesis in porcine granulosa cells Endocrinology. 137: 4657-4664. PMID 8895330 DOI: 10.1210/Endo.137.11.8895330  0.52
1996 De La Sota RL, Simmen FA, Diaz T, Thatcher WW. Insulin-like growth factor system in bovine first-wave dominant and subordinate follicles Biology of Reproduction. 55: 803-812. PMID 8879493 DOI: 10.1095/Biolreprod55.4.803  0.52
1996 Song S, Young Lee C, Green ML, Chung CS, Simmen RCM, Simmen FA. The unique endometrial expression and genomic organization of the porcine ICFBP-2 gene Molecular and Cellular Endocrinology. 120: 193-202. PMID 8832579 DOI: 10.1016/0303-7207(96)03837-3  0.52
1996 Choi I, Simmen RCM, Simmen FA. Molecular Cloning of Cytochrome P450 Aromatase Complementary Deoxyribonucleic Acid from Periimplantation Porcine and Equine Blastocysts Identifies Multiple Novel 5′-Untranslated Exons Expressed in Embryos, Endometrium, and Placenta Endocrinology. 137: 1457-1467. PMID 8625924 DOI: 10.1210/Endo.137.4.8625924  0.52
1995 Green ML, Simmen RCM, Simmen FA. Developmental regulation of steroidogenic enzyme gene expression in the periimplantation porcine conceptus: A paracrine role for insulin-like growth factor-I Endocrinology. 136: 3961-3970. PMID 7649105 DOI: 10.1210/Endo.136.9.7649105  0.52
1995 Lucy MC, Thatcher WW, Collier RJ, Simmen FA, Ko Y, Savio JD, Badinga L. Effects of somatotropin on the conceptus, uterus, and ovary during maternal recognition of pregnancy in cattle. Domestic Animal Endocrinology. 12: 73-82. PMID 7542581 DOI: 10.1016/0739-7240(94)00010-X  0.52
1995 Jaworski DC, Simmen FA, Lamoreaux W, Coons LB, Muller MT, Needham GR. A secreted calreticulin protein in ixodid tick (Amblyomma americanum) saliva Journal of Insect Physiology. 41: 369-375. DOI: 10.1016/0022-1910(94)00107-R  0.52
1994 Ko Y, Choi I, Green ML, Simmen FA, Simmen RCM. Transient expression of the cytochrome P450 aromatase gene in elongating porcine blastocysts is correlated with uterine insulin-like growth factor levels during peri-implantation development Molecular Reproduction and Development. 37: 1-11. PMID 8129925 DOI: 10.1002/Mrd.1080370102  0.52
1994 Ko Yong, Simmen RCM, Lee CY, Simmen FA. Reversion to the nontransformed phenotype of tsSV40-transformed uterine endometrial epithelial cells is accompanied by decreased mitogenic responsiveness to IGFs and by enhanced secretion of at least five different IGF binding proteins Endocrine. 2: 495-504.  0.52
1993 Reinhart GA, Mahan DC, Lepine AJ, Simmen FA, Moore BE. Dietary clofibric acid increases intestinal fatty acid binding protein activity and apparent lipid digestibility in weanling swine. Journal of Animal Science. 71: 2693-9. PMID 8226370 DOI: 10.2527/1993.71102693X  0.52
1993 Lee CY, Bazer FW, Simmen FA. Expression of components of the insulin-like growth factor system in pig mammary glands and serum during pregnancy and pseudopregnancy: Effects of oestrogen Journal of Endocrinology. 137: 473-483. PMID 7690391 DOI: 10.1677/Joe.0.1370473  0.52
1993 Lee CY, Chung CS, Simmen FA. Ontogeny of the porcine insulin-like growth factor system Molecular and Cellular Endocrinology. 93: 71-80. PMID 7686518 DOI: 10.1016/0303-7207(93)90141-6  0.52
1993 Simmen RCM, Ko Y, Simmen FA. Insulin-like growth factors and blastocyst development Theriogenology. 39: 163-175. DOI: 10.1016/0093-691X(93)90031-Y  0.52
1992 Simmen FA, Simmen RCM, Geisert RD, Martinat-Botte F, Bazer FW, Terqui M. Differential expression, during the estrous cycle and pre- and postimplantation conceptus development, of messenger ribonucleic acids encoding components of the pig uterine insulin-like growth factor system Endocrinology. 130: 1547-1556. PMID 1537304 DOI: 10.1210/Endo.130.3.1537304  0.52
1992 Reinhart GA, Simmen FA, Mahan DC, Simmen RCM, White ME, Trulzsch DV. Perinatal ontogeny of fatty acid binding protein activity in porcine small intestine Nutrition Research. 12: 1345-1356. DOI: 10.1016/S0271-5317(05)80533-0  0.52
1991 Simmen FA. Expression of the insulin-like growth factor-I gene and its products: complex regulation by tissue specific and hormonal factors Domestic Animal Endocrinology. 8: 165-178. PMID 2070595 DOI: 10.1016/0739-7240(91)90053-M  0.52
1991 Bazer FW, Simmen RCM, Simmen FA. Comparative aspects of conceptus signals for maternal recognition of pregnancy Annals of the New York Academy of Sciences. 622: 202-211. PMID 2064181 DOI: 10.1111/J.1749-6632.1991.Tb37863.X  0.52
1991 Simmen RCM, Simmen FA, Bazer FW. Regulation of synthesis of uterine secretory proteins: Evidence for differential induction of porcine uteroferrin and antileukoproteinase gene expression Biology of Reproduction. 44: 191-200. PMID 2015349 DOI: 10.1095/Biolreprod44.1.191  0.52
1991 Simmen FA, Simmen RCM. Peptide growth factors and proto-oncogenes in mammalian conceptus development Biology of Reproduction. 44: 1-5. PMID 2015340 DOI: 10.1095/Biolreprod44.1.1  0.52
1991 Ko Y, Lee CY, Ott TL, Davis MA, Simmen RCM, Bazer FW, Simmen FA. Insulin-like growth factors in sheep uterine fluids: Concentrations and relationship to ovine trophoblast protein-1 production during early pregnancy Biology of Reproduction. 45: 135-142. PMID 1878428 DOI: 10.1095/Biolreprod45.1.135  0.52
1991 Hofig A, Simmen FA, Bazer FW, Simmen RCM. Effects of insulin-like growth factor-1 on aromatase cytochrome P450 activity and oestradiol biosynthesis in preimplantation porcine conceptuses in vitro Journal of Endocrinology. 130: 245-250. PMID 1833500 DOI: 10.1677/Joe.0.1300245  0.52
1991 Geisert RD, Lee CY, Simmen FA, Zavy MT, Fliss AE, Bazer FW, Simmen RC. Expression of messenger RNAs encoding insulin-like growth factor-I, -II, and insulin-like growth factor binding protein-2 in bovine endometrium during the estrous cycle and early pregnancy. Biology of Reproduction. 45: 975-83. PMID 1725270 DOI: 10.1095/Biolreprod45.6.975  0.52
1991 Lee CY, Bazer FW, Etherton TD, Simmen FA. Ontogeny of insulin-like growth factors (IGF-I and IGF-II) and IGF-binding proteins in porcine serum during fetal and postnatal development Endocrinology. 128: 2336-2344. PMID 1708333 DOI: 10.1210/Endo-128-5-2336  0.52
1991 Bishop MD, Tavakkol A, Threadgill DW, Simmen FA, Simmen RC, Davis ME, Womack JE. Somatic cell mapping and restriction fragment length polymorphism analysis of bovine insulin-like growth factor I Journal of Animal Science. 69: 4306-4311. PMID 1684360 DOI: 10.2527/1991.69114306X  0.52
1991 Hofig A, Michel FJ, Simmen FA, Simmen RCM. Constitutive expression of uterine receptors for insulin-like growth factor-I during the peri-implantation period in the pig Biology of Reproduction. 45: 533-539. PMID 1661183 DOI: 10.1095/Biolreprod45.4.533  0.52
1990 Simmen FA, Whang KY, Simmen RC, Peterson GA, Bishop MD, Irvin KM. Lactational variation and relationship to postnatal growth of insulin-like growth factor-I in mammary secretions from genetically diverse sows. Domestic Animal Endocrinology. 7: 199-206. PMID 2369820 DOI: 10.1016/0739-7240(90)90026-V  0.52
1990 Tan TJ, Schober DA, Simmen FA. Fibroblast mitogens in swine milk include an epidermal growth factor-related peptide Regulatory Peptides. 27: 61-74. PMID 2309048 DOI: 10.1016/0167-0115(90)90205-B  0.52
1990 Jaworski DC, Muller MT, Simmen FA, Needham GR. Amblyomma americanum: Identification of tick salivary gland antigens from unfed and early feeding females with comparisons to Ixodes dammini and Dermacentor variabilis Experimental Parasitology. 70: 217-226. PMID 2298277 DOI: 10.1016/0014-4894(90)90102-I  0.52
1990 Simmen FA, Cera KR, Mahan DC. Stimulation by colostrum or mature milk of gastrointestinal tissue development in newborn pigs Journal of Animal Science. 68: 3596-3603. PMID 2262412 DOI: 10.2527/1990.68113596X  0.52
1990 Simmen RC, Simmen FA. Regulation of uterine and conceptus secretory activity in the pig Journal of Reproduction and Fertility. Supplement. 40: 279-292. PMID 2192044  0.52
1990 Leaman DW, Simmen FA, Ramsay TG, White ME. Insulin-like growth factor-I and -II messenger RNA expression in muscle, heart, and liver of streptozotocin-diabetic swine Endocrinology. 126: 2850-2857. PMID 2190798 DOI: 10.1210/Endo-126-6-2850  0.52
1990 Simmen RCM, Simmen FA, Hofig A, Farmer SJ, Bazer FW. Hormonal regulation of insulin-like growth factor gene expression in pig uterus Endocrinology. 127: 2166-2174. PMID 2171908 DOI: 10.1210/Endo-127-5-2166  0.52
1990 Schober DA, Simmen FA, Hadsell DL, Baumrucker CR. Perinatal expression of type I IGF receptors in porcine small intestine Endocrinology. 126: 1125-1132. PMID 2153520 DOI: 10.1210/Endo-126-2-1125  0.52
1990 Reinhart GA, Simmen FA, Mahan DC, Simmen RCM, White ME. Isolation, characterization, and developmental expression of pig intestinal fatty acid-binding proteins The Journal of Nutritional Biochemistry. 1: 592-598. DOI: 10.1016/0955-2863(90)90049-Q  0.52
1989 Simmen RC, Simmen FA, Ko Y, Bazer FW. Differential growth factor content of uterine luminal fluids from large white and prolific Meishan pigs during the estrous cycle and early pregnancy Journal of Animal Science. 67: 1538-1545. PMID 2768111 DOI: 10.2527/Jas1989.6761538X  0.52
1989 Needham GR, Jaworski DC, Simmen FA, Sherif N, Muller MT. Characterization of ixodid tick salivary-gland gene products, using recombinant DNA technology Experimental &Amp; Applied Acarology. 7: 21-32. PMID 2758938 DOI: 10.1007/Bf01200450  0.52
1989 Bishop MD, Simmen RC, Simmen FA, Davis ME. The relationship of insulin-like growth factor-I with postweaning performance in Angus beef cattle Journal of Animal Science. 67: 2872-2880. PMID 2592275 DOI: 10.2527/Jas1989.67112872X  0.52
1989 Letcher R, Simmen RCM, Bazer FW, Simmen FA. Insulin-like growth factor-I expression during early conceptus development in the pig Biology of Reproduction. 41: 1143-1151. PMID 2483128 DOI: 10.1095/Biolreprod41.6.1143  0.52
1988 Simmen RC, Ko Y, Liu XH, Wilde MH, Pope WF, Simmen FA. A uterine cell mitogen distinct from epidermal growth factor in porcine uterine luminal fluids: characterization and partial purification. Biology of Reproduction. 38: 551-61. PMID 3259897 DOI: 10.1095/Biolreprod38.3.551  0.52
1988 Tavakkol A, Simmen FA, Simmen RCM. Porcine insulin-like growth factor-I (pIGF-I): Complementary deoxyribonucleic acid cloning and uterine expression of messenger ribonucleic acid encoding evolutionarily conserved IGF-I peptides Molecular Endocrinology. 2: 674-681. PMID 3211153 DOI: 10.1210/Mend-2-8-674  0.52
1988 Simmen FA, Simmen RCM, Reinhart G. Maternal and neonatal somatomedin C/insulin-like growth factor-I (IGF-I) and IGF binding proteins during early lactation in the pig Developmental Biology. 130: 16-27. PMID 2460388 DOI: 10.1016/0012-1606(88)90409-5  0.52
1987 Simmen FA. Expression of the avian c-erb B (EGF receptor) protooncogene during estrogen-promoted oviduct growth Bba - Gene Structure and Expression. 910: 182-188. PMID 3676321 DOI: 10.1016/0167-4781(87)90071-6  0.52
1987 Cera K, Mahan DC, Simmen FA. In vitro growth-promoting activity of porcine mammary secretions: initial characterization and relationship to known peptide growth factors Journal of Animal Science. 65: 1149-1159. PMID 3667456 DOI: 10.2527/Jas1987.6541149X  0.52
1986 Simmen FA, Mandel M, Humphreys T. Length and sequence polymorphisms in the ribosomal gene spacer of the Hawaiian sea urchin, T. gratilla Biochemical and Biophysical Research Communications. 137: 834-840. PMID 3729940 DOI: 10.1016/0006-291X(86)91155-1  0.52
1985 Simmen FA, Dolecki GJ, Carlos R, Mandel M, Humphreys T. Structural analysis of ribosomal RNA genes from the Hawaiian sea urchin species, Tripneustes gratilla Dna. 4: 385-393. PMID 4075956  0.52
1985 Simmen FA, Schulz TZ, O'Malley BW. Expression of the chick cellular erb B locus is regulated by steroid hormones Federation Proceedings. 44.  0.52
1984 Simmen FA, Schulz TZ, Headon DR, Wright DA, Carpenter G, O'Malley BW. Translation in Xenopus oocytes of messenger RNA from A431 cells for human epidermal growth factor receptor proteins Dna. 3: 393-399. PMID 6096098  0.52
1984 Simmen FA, Gope ML, Schulz TZ, Wright DA, Carpenter G, O'Malley BW. Isolation of an evolutionarily conserved epidermal growth factor receptor cDNA from human A431 carcinoma cells Biochemical and Biophysical Research Communications. 124: 125-132. PMID 6093780 DOI: 10.1016/0006-291X(84)90926-4  0.52
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