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Priscilla L. Yang - Publications

Affiliations: 
2021- Microbiology and Immunology Stanford University School of Medicine, Palo Alto, CA, United States 
Area:
Virology Biology, Biochemistry, chemical biology
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55 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Chakravarty A, Yang PL. Targeted protein degradation as an antiviral approach. Antiviral Research. 105480. PMID 36567024 DOI: 10.1016/j.antiviral.2022.105480  0.342
2022 Boytz R, Słabicki M, Ramaswamy S, Patten JJ, Zou C, Meng C, Hurst BL, Wang J, Nowak RP, Yang PL, Sattler M, Stone RM, Griffin JD, Gray NS, Gummuluru S, et al. Anti-SARS-CoV-2 Activity of Targeted Kinase Inhibitors: Repurposing Clinically Available Drugs for COVID-19 Therapy. Journal of Medical Virology. PMID 36117402 DOI: 10.1002/jmv.28157  0.43
2021 Liu HY, Yang PL. Small-Molecule Inhibition of Viral Fusion Glycoproteins. Annual Review of Virology. PMID 34197186 DOI: 10.1146/annurev-virology-022221-063725  0.811
2021 Yang PL. Antiviral Therapeutics. Acs Infectious Diseases. PMID 34061494 DOI: 10.1021/acsinfecdis.1c00271  0.3
2020 de Wispelaere M, Carocci M, Burri DJ, Neidermyer WJ, Olson CM, Roggenbach I, Liang Y, Wang J, Whelan SPJ, Gray NS, Yang PL. A broad-spectrum antiviral molecule, QL47, selectively inhibits eukaryotic translation. The Journal of Biological Chemistry. 295: 1694-1703. PMID 33485559 DOI: 10.1074/jbc.RA119.011132  0.355
2020 Weisberg E, Parent A, Yang PL, Sattler M, Liu Q, Liu Q, Wang J, Meng C, Buhrlage SJ, Gray N, Griffin JD. Repurposing of Kinase Inhibitors for Treatment of COVID-19. Pharmaceutical Research. 37: 167. PMID 32778962 DOI: 10.1007/S11095-020-02851-7  0.514
2020 Yang PL. Call for Papers: Antiviral Therapeutics Acs Infectious Diseases. PMID 32646218 DOI: 10.1021/Acsinfecdis.0C00399  0.332
2020 Tallorin L, Villareal VA, Hsia CY, Rodgers MA, Burri DJ, Pfeil MP, Llopis PM, Lindenbach BD, Yang PL. Hepatitis C virus NS3-4A protease regulates the lipid environment for RNA replication by cleaving host enzyme 24-dehydrocholesterol reductase. The Journal of Biological Chemistry. PMID 32641492 DOI: 10.1074/Jbc.Ra120.013455  0.745
2020 Weisberg E, Sattler M, Yang PL, Parent A, Gray N, Griffin JD. Current Therapies Under Investigation for COVID-19. Canadian Journal of Physiology and Pharmacology. PMID 32640179 DOI: 10.1139/Cjpp-2020-0286  0.473
2020 Ramanathan HN, Zhang S, Douam F, Mar KB, Chang J, Yang PL, Schoggins JW, Ploss A, Lindenbach BD. A Sensitive Yellow Fever Virus Entry Reporter Identifies Valosin-Containing Protein (VCP/p97) as an Essential Host Factor for Flavivirus Uncoating. Mbio. 11. PMID 32291299 DOI: 10.1128/Mbio.00467-20  0.476
2019 de Wispelaere M, Carocci M, Burri DJ, Neidermyer WJ, Olson CM, Roggenbach I, Liang Y, Wang J, Whelan SPJ, Gray NS, Yang PL. A broad-spectrum antiviral molecule, QL47, selectively inhibits eukaryotic translation. The Journal of Biological Chemistry. PMID 31914414 DOI: 10.1074/Jbc.Ra119.011132  0.816
2019 Lian W, Jang J, Potisopon S, Li PC, Rahmeh A, Wang J, Kwiatkowski NP, Gray NS, Yang PL. Correction to Discovery of Immunologically Inspired Small Molecules That Target the Viral Envelope Protein. Acs Infectious Diseases. PMID 31675213 DOI: 10.1021/Acsinfecdis.9B00401  0.796
2019 de Wispelaere M, Du G, Donovan KA, Zhang T, Eleuteri NA, Yuan JC, Kalabathula J, Nowak RP, Fischer ES, Gray NS, Yang PL. Small molecule degraders of the hepatitis C virus protease reduce susceptibility to resistance mutations. Nature Communications. 10: 3468. PMID 31371704 DOI: 10.1038/S41467-019-11429-W  0.626
2019 Pitts J, Hsia CY, Lian W, Wang J, Pfeil MP, Kwiatkowski N, Li Z, Jang J, Gray NS, Yang PL. Identification of small molecule inhibitors targeting the Zika virus envelope protein. Antiviral Research. PMID 30771406 DOI: 10.1016/J.Antiviral.2019.02.008  0.822
2019 Schmidt AG, Lee K, Yang PL, Harrison SC. Correction: Small-Molecule Inhibitors of Dengue-Virus Entry. Plos Pathogens. 15: e1007553. PMID 30703168 DOI: 10.1371/Journal.Ppat.1007553  0.689
2019 Li PC, Jang J, Hsia CY, Groomes P, Lian W, de Wispelaere M, Pitts JD, Wang J, Kwaitkowski N, Gray NS, Yang PL. Small molecules targeting the flavivirus E protein with broad-spectrum activity and antiviral efficacy in vivo. Acs Infectious Diseases. PMID 30608640 DOI: 10.1021/Acsinfecdis.8B00322  0.816
2018 Lian W, Jang J, Potisopon S, Li PC, Rahmeh A, Wang J, Kwiatkowski NP, Gray NS, Yang PL. Discovery of Immunologically Inspired Small Molecules that Target the Viral Envelope Protein. Acs Infectious Diseases. PMID 30027735 DOI: 10.1021/Acsinfecdis.8B00127  0.823
2018 Chao LH, Jang J, Johnson A, Nguyen A, Gray N, Yang PL, Harrison SC. How small-molecule inhibitors of dengue-virus infection interfere with viral membrane fusion. Elife. 7. PMID 29999491 DOI: 10.7554/Elife.36461  0.682
2018 de Wispelaere M, Lian W, Potisopon S, Li PC, Jang J, Ficarro SB, Clark MJ, Zhu X, Kaplan JB, Pitts JD, Wales TE, Wang J, Engen JR, Marto JA, Gray NS, ... Yang PL, et al. Inhibition of Flaviviruses by Targeting a Conserved Pocket on the Viral Envelope Protein. Cell Chemical Biology. PMID 29937406 DOI: 10.1016/J.Chembiol.2018.05.011  0.769
2018 Chao LH, Jang J, Johnson A, Nguyen A, Gray NS, Yang PL, Harrison SC. Author response: How small-molecule inhibitors of dengue-virus infection interfere with viral membrane fusion Elife. DOI: 10.7554/Elife.36461.014  0.614
2017 Pitts JD, Li PC, de Wispelaere M, Yang PL. Antiviral activity of fenretinide against Zika virus. Antiviral Research. PMID 29051080 DOI: 10.1016/J.Antiviral.2017.10.014  0.71
2017 Liang Y, de Wispelaere M, Carocci M, Liu Q, Wang J, Yang PL, Gray NS. Structure-Activity Relationship Study of QL47: A Broad-Spectrum Antiviral Agent. Acs Medicinal Chemistry Letters. 8: 344-349. PMID 28337328 DOI: 10.1021/Acsmedchemlett.7B00008  0.587
2016 de Wispelaere M, Carocci M, Liang Y, Liu Q, Sun E, Vetter ML, Wang J, Gray NS, Yang PL. Discovery of host-targeted covalent inhibitors of dengue virus. Antiviral Research. PMID 28034743 DOI: 10.1016/J.Antiviral.2016.12.017  0.647
2016 Costello DA, Villareal VA, Yang PL. Desmosterol Increases Lipid Bilayer Fluidity during Hepatitis C Virus Infection. Acs Infectious Diseases. 2: 852-862. PMID 27933788 DOI: 10.1021/Acsinfecdis.6B00086  0.806
2016 Villareal VA, Fu D, Costello DA, Xie XS, Yang PL. Hepatitis C Virus Selectively Alters the Intracellular Localization of Desmosterol. Acs Chemical Biology. PMID 27128812 DOI: 10.1021/Acschembio.6B00324  0.813
2016 Clark MJ, Miduturu C, Schmidt AG, Zhu X, Pitts JD, Wang J, Potisopon S, Zhang J, Wojciechowski A, Hann Chu JJ, Gray NS, Yang PL. GNF-2 Inhibits Dengue Virus by Targeting Abl Kinases and the Viral E Protein. Cell Chemical Biology. 23: 443-452. PMID 27105280 DOI: 10.1016/J.Chembiol.2016.03.010  0.798
2016 Chou YY, Cuevas C, Carocci M, Stubbs SH, Ma M, Cureton DK, Chao L, Evesson F, He K, Yang PL, Whelan SP, Ross SR, Kirchhausen T, Gaudin R. Identification and characterization of a novel broad spectrum virus entry inhibitor. Journal of Virology. PMID 26912630 DOI: 10.1128/Jvi.00103-16  0.506
2016 Carocci M, Yang PL. Lactimidomycin is a broad-spectrum inhibitor of dengue and other RNA viruses. Antiviral Research. PMID 26872864 DOI: 10.1016/J.Antiviral.2016.02.005  0.512
2015 Villareal VA, Rodgers MA, Costello DA, Yang PL. Targeting host lipid synthesis and metabolism to inhibit dengue and hepatitis C viruses. Antiviral Research. PMID 26526588 DOI: 10.1016/J.Antiviral.2015.10.013  0.818
2015 Carocci M, Hinshaw SM, Rodgers MA, Villareal VA, Burri DJ, Pilankatta R, Maharaj NP, Gack MU, Stavale EJ, Warfield KL, Yang PL. The bioactive lipid 4-hydroxyphenyl retinamide inhibits flavivirus replication. Antimicrobial Agents and Chemotherapy. 59: 85-95. PMID 25313218 DOI: 10.1128/Aac.04177-14  0.795
2015 Carocci M, Yang PL, Kuhn JH. Flaviviruses: Introduction to dengue viruses Global Virology I-Identifying and Investigating Viral Diseases. 403-424. DOI: 10.1007/978-1-4939-2410-3_15  0.333
2014 Vetter ML, Zhang Z, Liu S, Wang J, Cho H, Zhang J, Zhang W, Gray NS, Yang PL. Fluorescent visualization of Src by using dasatinib-BODIPY. Chembiochem : a European Journal of Chemical Biology. 15: 1317-24. PMID 24828915 DOI: 10.1002/Cbic.201402010  0.457
2013 de Wispelaere M, LaCroix AJ, Yang PL. The small molecules AZD0530 and dasatinib inhibit dengue virus RNA replication via Fyn kinase. Journal of Virology. 87: 7367-81. PMID 23616652 DOI: 10.1128/Jvi.00632-13  0.476
2012 Vetter ML, Rodgers MA, Patricelli MP, Yang PL. Chemoproteomic profiling identifies changes in DNA-PK as markers of early dengue virus infection. Acs Chemical Biology. 7: 2019-26. PMID 22999307 DOI: 10.1021/Cb300420Z  0.643
2012 Zhang Z, Kwiatkowski N, Zeng H, Lim SM, Gray NS, Zhang W, Yang PL. Leveraging kinase inhibitors to develop small molecule tools for imaging kinases by fluorescence microscopy. Molecular Biosystems. 8: 2523-6. PMID 22673640 DOI: 10.1039/C2Mb25099C  0.458
2012 de Wispelaere M, Yang PL. Mutagenesis of the DI/DIII linker in dengue virus envelope protein impairs viral particle assembly. Journal of Virology. 86: 7072-83. PMID 22532681 DOI: 10.1128/Jvi.00224-12  0.443
2012 Schmidt AG, Lee K, Yang PL, Harrison SC. Small-molecule inhibitors of dengue-virus entry. Plos Pathogens. 8: e1002627. PMID 22496653 DOI: 10.1371/Journal.Ppat.1002627  0.716
2012 Rodgers MA, Villareal VA, Schaefer EA, Peng LF, Corey KE, Chung RT, Yang PL. Lipid metabolite profiling identifies desmosterol metabolism as a new antiviral target for hepatitis C virus. Journal of the American Chemical Society. 134: 6896-9. PMID 22480142 DOI: 10.1021/Ja207391Q  0.818
2011 Yang PL, Gao M, Lin K, Liu Q, Villareal VA. Anti-HCV drugs in the pipeline. Current Opinion in Virology. 1: 607-16. PMID 22440918 DOI: 10.1016/J.Coviro.2011.10.019  0.78
2010 Schmidt AG, Yang PL, Harrison SC. Peptide inhibitors of flavivirus entry derived from the E protein stem. Journal of Virology. 84: 12549-54. PMID 20881042 DOI: 10.1128/Jvi.01440-10  0.669
2010 Schmidt AG, Yang PL, Harrison SC. Peptide inhibitors of dengue-virus entry target a late-stage fusion intermediate. Plos Pathogens. 6: e1000851. PMID 20386713 DOI: 10.1371/Journal.Ppat.1000851  0.701
2010 Yang PL, Althage A, Chung J, Maier H, Wieland S, Isogawa M, Chisari FV. Immune effectors required for hepatitis B virus clearance. Proceedings of the National Academy of Sciences of the United States of America. 107: 798-802. PMID 20080755 DOI: 10.1073/Pnas.0913498107  0.561
2010 Schmidt AG, Yang PL, Harrison SC. Peptide inhibitors of dengue-virus entry target a late- stage fusion intermediate Plos Pathogens. 6: 1-11.  0.669
2009 Sessions OM, Barrows NJ, Souza-Neto JA, Robinson TJ, Hershey CL, Rodgers MA, Ramirez JL, Dimopoulos G, Yang PL, Pearson JL, Garcia-Blanco MA. Discovery of insect and human dengue virus host factors. Nature. 458: 1047-50. PMID 19396146 DOI: 10.1038/Nature07967  0.669
2009 Rodgers MA, Saghatelian A, Yang PL. Identification of an overabundant cholesterol precursor in hepatitis B virus replicating cells by untargeted lipid metabolite profiling. Journal of the American Chemical Society. 131: 5030-1. PMID 19301856 DOI: 10.1021/Ja809949R  0.695
2009 Zhang J, Yang PL, Gray NS. Targeting cancer with small molecule kinase inhibitors. Nature Reviews. Cancer. 9: 28-39. PMID 19104514 DOI: 10.1038/Nrc2559  0.476
2008 Hwang YC, Chu JJ, Yang PL, Chen W, Yates MV. Rapid identification of inhibitors that interfere with poliovirus replication using a cell-based assay. Antiviral Research. 77: 232-6. PMID 18243348 DOI: 10.1016/J.Antiviral.2007.12.009  0.605
2007 Chu JJ, Yang PL. c-Src protein kinase inhibitors block assembly and maturation of dengue virus. Proceedings of the National Academy of Sciences of the United States of America. 104: 3520-5. PMID 17360676 DOI: 10.1073/Pnas.0611681104  0.681
2002 Yang PL, Althage A, Chung J, Chisari FV. Hydrodynamic injection of viral DNA: a mouse model of acute hepatitis B virus infection. Proceedings of the National Academy of Sciences of the United States of America. 99: 13825-30. PMID 12374864 DOI: 10.1073/Pnas.202398599  0.614
2002 Gildersleeve J, Janes J, Ulrich H, Yang P, Barbas C, Schultz PG. Development of a genetic selection for catalytic antibodies. Bioorganic & Medicinal Chemistry Letters. 12: 1691-4. PMID 12039592 DOI: 10.1016/S0960-894X(02)00198-1  0.75
2002 Gildersleeve J, Janes J, Ulrich H, Yang P, Barbas C, Schultz PG. Corrigendum to “Development of a Genetic Selection for Catalytic Antibodies” [Bioorg. Med. Chem. Lett. 12 (2002) 1691]† Bioorganic & Medicinal Chemistry Letters. 12: 2789. DOI: 10.1016/S0960-894X(02)00562-0  0.743
2001 Yin J, Mundorff EC, Yang PL, Wendt KU, Hanway D, Stevens RC, Schultz PG. A comparative analysis of the immunological evolution of antibody 28B4. Biochemistry. 40: 10764-73. PMID 11535051 DOI: 10.1021/Bi010536C  0.669
1999 Yang PL, Schultz PG. Mutational analysis of the affinity maturation of antibody 48G7. Journal of Molecular Biology. 294: 1191-201. PMID 10600377 DOI: 10.1006/Jmbi.1999.3197  0.667
1996 Patten PA, Gray NS, Yang PL, Marks CB, Wedemayer GJ, Boniface JJ, Stevens RC, Schultz PG. The immunological evolution of catalysis. Science (New York, N.Y.). 271: 1086-91. PMID 8599084 DOI: 10.1126/Science.271.5252.1086  0.752
1995 Ulrich HD, Patten PA, Yang PL, Romesberg FE, Schultz PG. Expression studies of catalytic antibodies. Proceedings of the National Academy of Sciences of the United States of America. 92: 11907-11. PMID 8524873 DOI: 10.1073/Pnas.92.25.11907  0.748
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