Periannan Kuppusamy - Publications

Affiliations: 
Biophysics Ohio State University, Columbus, Columbus, OH 
Area:
General Biophysics

269 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Mast JM, Hinds JW, Tse D, Axelrod K, Kuppusamy ML, Kmiec MM, Bognár B, Kálai T, Kuppusamy P. Selective Induction of Cellular Toxicity and Anti-tumor Efficacy by N-Methylpiperazinyl Diarylidenylpiperidone and its Pro-nitroxide Conjugate through ROS-mediated Mitochondrial Dysfunction and G2/M Cell-cycle Arrest in Human Pancreatic Cancer. Cell Biochemistry and Biophysics. PMID 32449075 DOI: 10.1007/s12013-020-00919-0  0.36
2019 Madan E, Parker TM, Pelham CJ, Palma AM, Peixoto ML, Nagane M, Chandaria A, Tomás AR, Canas-Marques R, Henriques V, Galzerano A, Cabral-Teixeira J, Selvendiran K, Kuppusamy P, Carvalho C, et al. HIF-transcribed p53 chaperones HIF-1α. Nucleic Acids Research. PMID 31538203 DOI: 10.1093/Nar/Gkz766  0.32
2019 Kmiec MM, Hou H, Kuppusamy ML, Drews TM, Prabhat AM, Petryakov SV, Demidenko E, Schaner PE, Buckey JC, Blank A, Kuppusamy P. Application of SPOT chip for transcutaneous oximetry. Magnetic Resonance in Medicine. PMID 30761605 DOI: 10.1002/Mrm.27667  0.36
2018 Prabhat AM, Kuppusamy ML, Bognár B, Kálai T, Hideg K, Kuppusamy P. Antiproliferative Effect of a Novel 4,4'-Disulfonyldiarylidenyl Piperidone in Human Colon Cancer Cells. Cell Biochemistry and Biophysics. PMID 30552554 DOI: 10.1007/s12013-018-0862-5  0.36
2018 Prabhat AM, Kuppusamy ML, Naidu SK, Meduru S, Reddy PT, Dominic A, Khan M, Rivera BK, Kuppusamy P. Supplemental Oxygen Protects Heart Against Acute Myocardial Infarction. Frontiers in Cardiovascular Medicine. 5: 114. PMID 30211171 DOI: 10.3389/fcvm.2018.00114  0.36
2018 Hou H, Khan N, Gohain S, Kuppusamy ML, Kuppusamy P. Pre-clinical evaluation of OxyChip for long-term EPR oximetry. Biomedical Microdevices. 20: 29. PMID 29549438 DOI: 10.1007/s10544-018-0272-x  0.36
2018 Nagane M, Kuppusamy ML, An J, Mast JM, Gogna R, Yasui H, Yamamori T, Inanami O, Kuppusamy P. Ataxia-Telangiectasia Mutated (ATM) Kinase Regulates eNOS Expression and Modulates Radiosensitivity in Endothelial Cells Exposed to Ionizing Radiation. Radiation Research. PMID 29474156 DOI: 10.1667/RR14781.1  0.36
2018 Madan E, Parker TM, Bauer MR, Dhiman A, Pelham CJ, Nagane M, Kuppusamy ML, Holmes M, Holmes TR, Shaik K, Shee K, Kiparoidze S, Smith SD, Park YA, Gomm J, ... ... Kuppusamy P, et al. The curcumin analog HO-3867 selectively kills cancer cells by converting mutant p53 protein to transcriptionally active wildtype p53. The Journal of Biological Chemistry. PMID 29382728 DOI: 10.1074/jbc.RA117.000950  0.36
2016 Hou H, Khan N, Nagane M, Gohain S, Chen EY, Jarvis LA, Schaner PE, Williams BB, Flood AB, Swartz HM, Kuppusamy P. Skeletal Muscle Oxygenation Measured by EPR Oximetry Using a Highly Sensitive Polymer-Encapsulated Paramagnetic Sensor. Advances in Experimental Medicine and Biology. 923: 351-357. PMID 27526163 DOI: 10.1007/978-3-319-38810-6_46  0.36
2016 Swartz HM, Williams BB, Hou H, Khan N, Jarvis LA, Chen EY, Schaner PE, Ali A, Gallez B, Kuppusamy P, Flood AB. Direct and Repeated Clinical Measurements of pO2 for Enhancing Cancer Therapy and Other Applications. Advances in Experimental Medicine and Biology. 923: 95-104. PMID 27526130 DOI: 10.1007/978-3-319-38810-6_13  0.36
2016 ElNaggar AC, Saini U, Naidu S, Wanner R, Sudhakar M, Fowler J, Nagona M, Kuppusamy P, Cohn DE, Selvendiran K. Anticancer potential of diarylidenyl piperidone derivatives, HO-4200 and H-4318, in cisplatin resistant primary ovarian cancer. Cancer Biology & Therapy. 0. PMID 27415751 DOI: 10.1080/15384047.2016.1210733  0.32
2016 Saini U, Naidu S, ElNaggar AC, Bid HK, Wallbillich JJ, Bixel K, Bolyard C, Suarez AA, Kaur B, Kuppusamy P, Hays J, Goodfellow PJ, Cohn DE, Selvendiran K. Elevated STAT3 expression in ovarian cancer ascites promotes invasion and metastasis: a potential therapeutic target. Oncogene. PMID 27292260 DOI: 10.1038/Onc.2016.197  0.32
2016 Fang D, Zhang Z, Li H, Yu Q, Douglas JT, Bratasz A, Kuppusamy P, Yan SS. Increased Electron Paramagnetic Resonance Signal Correlates with Mitochondrial Dysfunction and Oxidative Stress in an Alzheimer's disease Mouse Brain. Journal of Alzheimer's Disease : Jad. PMID 26890765 DOI: 10.3233/Jad-150917  0.36
2015 Ohanyan V, Yin L, Bardakjian R, Kolz C, Enrick M, Hakobyan T, Kmetz J, Bratz I, Luli J, Nagane M, Khan N, Hou H, Kuppusamy P, Graham J, Fu FK, et al. Requisite Role of Kv1.5 Channels in Coronary Metabolic Dilation. Circulation Research. 117: 612-21. PMID 26224794 DOI: 10.1161/Circresaha.115.306642  0.36
2015 Hashem M, Weiler-Sagie M, Kuppusamy P, Neufeld G, Neeman M, Blank A. Electron spin resonance microscopic imaging of oxygen concentration in cancer spheroids Journal of Magnetic Resonance. 256: 77-85. DOI: 10.1016/j.jmr.2015.04.012  0.36
2014 McCann GA, Naidu S, Rath KS, Bid HK, Tierney BJ, Suarez A, Varadharaj S, Zhang J, Hideg K, Houghton P, Kuppusamy P, Cohn DE, Selvendiran K. Targeting constitutively-activated STAT3 in hypoxic ovarian cancer, using a novel STAT3 inhibitor. Oncoscience. 1: 216-28. PMID 25594014 DOI: 10.18632/oncoscience.26  0.36
2014 Citro L, Naidu S, Hassan F, Kuppusamy ML, Kuppusamy P, Angelos MG, Khan M. Comparison of human induced pluripotent stem-cell derived cardiomyocytes with human mesenchymal stem cells following acute myocardial infarction. Plos One. 9: e116281. PMID 25551230 DOI: 10.1371/Journal.Pone.0116281  0.36
2014 Tierney BJ, McCann GA, Naidu S, Rath KS, Saini U, Wanner R, Kuppusamy P, Suarez A, Goodfellow PJ, Cohn DE, Selvendiran K. Aberrantly activated pSTAT3-Ser727 in human endometrial cancer is suppressed by HO-3867, a novel STAT3 inhibitor. Gynecologic Oncology. 135: 133-41. PMID 25038288 DOI: 10.1016/J.Ygyno.2014.07.087  0.36
2014 Khan N, Hou H, Hodge S, Kuppusamy M, Chen EY, Eastman A, Kuppusamy P, Swartz HM. Recurrent low-dose chemotherapy to inhibit and oxygenate head and neck tumors. Advances in Experimental Medicine and Biology. 812: 105-11. PMID 24729221 DOI: 10.1007/978-1-4939-0620-8_14  0.36
2014 Hou H, Khan N, Lariviere J, Hodge S, Chen EY, Jarvis LA, Eastman A, Williams BB, Kuppusamy P, Swartz HM. Skeletal muscle and glioma oxygenation by carbogen inhalation in rats: a longitudinal study by EPR oximetry using single-probe implantable oxygen sensors. Advances in Experimental Medicine and Biology. 812: 97-103. PMID 24729220 DOI: 10.1007/978-1-4939-0620-8_13  0.36
2014 Rivera BK, Naidu SK, Subramanian K, Joseph M, Hou H, Khan N, Swartz HM, Kuppusamy P. Real-time, in vivo determination of dynamic changes in lung and heart tissue oxygenation using EPR oximetry. Advances in Experimental Medicine and Biology. 812: 81-6. PMID 24729218 DOI: 10.1007/978-1-4939-0620-8_11  0.36
2014 Swartz HM, Hou H, Khan N, Jarvis LA, Chen EY, Williams BB, Kuppusamy P. Advances in probes and methods for clinical EPR oximetry. Advances in Experimental Medicine and Biology. 812: 73-9. PMID 24729217 DOI: 10.1007/978-1-4939-0620-8_10  0.36
2014 Reddy CA, Somepalli V, Golakoti T, Kanugula AK, Karnewar S, Rajendiran K, Vasagiri N, Prabhakar S, Kuppusamy P, Kotamraju S, Kutala VK. Mitochondrial-targeted curcuminoids: a strategy to enhance bioavailability and anticancer efficacy of curcumin. Plos One. 9: e89351. PMID 24622734 DOI: 10.1371/Journal.Pone.0089351  0.36
2014 Rath KS, Naidu SK, Lata P, Bid HK, Rivera BK, McCann GA, Tierney BJ, Elnaggar AC, Bravo V, Leone G, Houghton P, Hideg K, Kuppusamy P, Cohn DE, Selvendiran K. HO-3867, a safe STAT3 inhibitor, is selectively cytotoxic to ovarian cancer. Cancer Research. 74: 2316-27. PMID 24590057 DOI: 10.1158/0008-5472.Can-13-2433  0.36
2014 Swartz HM, Williams BB, Zaki BI, Hartford AC, Jarvis LA, Chen EY, Comi RJ, Ernstoff MS, Hou H, Khan N, Swarts SG, Flood AB, Kuppusamy P. Clinical EPR: unique opportunities and some challenges. Academic Radiology. 21: 197-206. PMID 24439333 DOI: 10.1016/J.Acra.2013.10.011  0.36
2014 Gupta K, Madan E, Sayyid M, Arias-Pulido H, Moreno E, Kuppusamy P, Gogna R. Oxygen regulates molecular mechanisms of cancer progression and metastasis. Cancer Metastasis Reviews. 33: 183-215. PMID 24338006 DOI: 10.1007/S10555-013-9464-2  0.36
2014 Wolfson H, Ahmad R, Twig Y, Kuppusamy P, Blank A. A Miniature Electron Spin Resonance Probehead for Transcutaneous Oxygen Monitoring Applied Magnetic Resonance. 45: 955-967. DOI: 10.1007/S00723-014-0593-8  0.36
2013 Sharma HS, Kutala VK, Kuppusamy P. Special issue on oxidative stress in health and disease. Cell Biochemistry and Biophysics. 67: 215-8. PMID 24142440 DOI: 10.1007/s12013-013-9774-6  0.36
2013 Gogna R, Madan E, Khan M, Pati U, Kuppusamy P. p53's choice of myocardial death or survival: Oxygen protects infarct myocardium by recruiting p53 on NOS3 promoter through regulation of p53-Lys(118) acetylation. Embo Molecular Medicine. 5: 1662-83. PMID 24096875 DOI: 10.1002/Emmm.201202055  0.36
2013 Saini U, Gumina RJ, Wolfe B, Kuppusamy ML, Kuppusamy P, Boudoulas KD. Preconditioning mesenchymal stem cells with caspase inhibition and hyperoxia prior to hypoxia exposure increases cell proliferation Journal of Cellular Biochemistry. 114: 2612-2623. PMID 23794477 DOI: 10.1002/jcb.24609  0.36
2013 Aune SE, Yeh ST, Kuppusamy P, Kuppusamy ML, Khan M, Angelos MG. Sivelestat attenuates myocardial reperfusion injury during brief low flow postischemic infusion. Oxidative Medicine and Cellular Longevity. 2013: 279847. PMID 23766850 DOI: 10.1155/2013/279847  0.36
2013 Rath KS, McCann GA, Cohn DE, Rivera BK, Kuppusamy P, Selvendiran K. Safe and targeted anticancer therapy for ovarian cancer using a novel class of curcumin analogs. Journal of Ovarian Research. 6: 35. PMID 23663277 DOI: 10.1186/1757-2215-6-35  0.36
2013 Fisher EM, Khan M, Salisbury R, Kuppusamy P. Noninvasive monitoring of small intestinal oxygen in a rat model of chronic mesenteric ischemia. Cell Biochemistry and Biophysics. 67: 451-9. PMID 23636684 DOI: 10.1007/S12013-013-9611-Y  0.36
2013 Ravi Y, Selvendiran K, Naidu SK, Meduru S, Citro LA, Bognár B, Khan M, Kálai T, Hideg K, Kuppusamy P, Sai-Sudhakar CB. Pulmonary hypertension secondary to left-heart failure involves peroxynitrite-induced downregulation of PTEN in the lung. Hypertension. 61: 593-601. PMID 23339168 DOI: 10.1161/Hypertensionaha.111.00514  0.36
2013 Madan E, Gogna R, Kuppusamy P, Bhatt M, Mahdi AA, Pati U. SCO2 induces p53-mediated apoptosis by Thr845 phosphorylation of ASK-1 and dissociation of the ASK-1-Trx complex. Molecular and Cellular Biology. 33: 1285-302. PMID 23319048 DOI: 10.1128/Mcb.06798-11  0.36
2013 Yan Y, Waite-Cusic JG, Kuppusamy P, Yousef AE. Intracellular free iron and its potential role in ultrahigh-pressure-induced inactivation of Escherichia coli. Applied and Environmental Microbiology. 79: 722-4. PMID 23124235 DOI: 10.1128/Aem.02202-12  0.36
2013 Damron FH, McKenney ES, Schweizer HP, Goldberg JB. Construction of a broad-host-range Tn7-based vector for single-copy P(BAD)-controlled gene expression in gram-negative bacteria. Applied and Environmental Microbiology. 79: 718-21. PMID 23124231 DOI: 10.1128/Aem.02926-12  0.36
2013 Elnakish MT, Kuppusamy P, Khan M. Stem cell transplantation as a therapy for cardiac fibrosis. The Journal of Pathology. 229: 347-54. PMID 23011894 DOI: 10.1002/path.4111  0.36
2013 Ravi Y, Selvendiran K, Meduru S, Citro L, Naidu S, Khan M, Rivera BK, Sai-Sudhakar CB, Kuppusamy P. Dysregulation of PTEN in cardiopulmonary vascular remodeling induced by pulmonary hypertension. Cell Biochemistry and Biophysics. 67: 363-72. PMID 22205501 DOI: 10.1007/S12013-011-9332-Z  0.36
2013 Khan M, Brauner ME, Plewa MC, Kutala VK, Angelos M, Kuppusamy P. Effect of pulmonary-generated reactive oxygen species on left-ventricular dysfunction associated with cardio-pulmonary ischemia-reperfusion injury. Cell Biochemistry and Biophysics. 67: 275-80. PMID 21947963 DOI: 10.1007/S12013-011-9299-9  0.32
2012 Tierney BJ, McCann GA, Cohn DE, Eisenhauer E, Sudhakar M, Kuppusamy P, Hideg K, Selvendiran K. HO-3867, a STAT3 inhibitor induces apoptosis by inactivation of STAT3 activity in BRCA1-mutated ovarian cancer cells. Cancer Biology & Therapy. 13: 766-75. PMID 22801507 DOI: 10.4161/cbt.20559  0.36
2012 Madan E, Gogna R, Kuppusamy P, Bhatt M, Pati U, Mahdi AA. TIGAR induces p53-mediated cell-cycle arrest by regulation of RB-E2F1 complex. British Journal of Cancer. 107: 516-26. PMID 22782351 DOI: 10.1038/bjc.2012.260  0.36
2012 Hassan F, Meduru S, Taguchi K, Kuppusamy ML, Mostafa M, Kuppusamy P, Khan M. Carvedilol enhances mesenchymal stem cell therapy for myocardial infarction via inhibition of caspase-3 expression. The Journal of Pharmacology and Experimental Therapeutics. 343: 62-71. PMID 22739507 DOI: 10.1124/jpet.112.196915  0.36
2012 Gogna R, Madan E, Kuppusamy P, Pati U. Re-oxygenation causes hypoxic tumor regression through restoration of p53 wild-type conformation and post-translational modifications. Cell Death & Disease. 3: e286. PMID 22419115 DOI: 10.1038/cddis.2012.15  0.36
2012 He S, Dayton A, Kuppusamy P, Werbovetz KA, Drew ME. Induction of oxidative stress in Trypanosoma brucei by the antitrypanosomal dihydroquinoline OSU-40. Antimicrobial Agents and Chemotherapy. 56: 2428-34. PMID 22314522 DOI: 10.1128/Aac.06386-11  0.36
2012 Ahmad R, Som S, Johnson DH, Zweier JL, Kuppusamy P, Potter LC. Multisite EPR oximetry from multiple quadrature harmonics. Journal of Magnetic Resonance (San Diego, Calif. : 1997). 214: 135-43. PMID 22154283 DOI: 10.1016/j.jmr.2011.10.016  0.36
2012 Gogna R, Madan E, Kuppusamy P, Pati U. Chaperoning of mutant p53 protein by wild-type p53 protein causes hypoxic tumor regression. The Journal of Biological Chemistry. 287: 2907-14. PMID 22147694 DOI: 10.1074/jbc.M111.317354  0.36
2012 Gogna R, Madan E, Kuppusamy P, Pati U. Reactive oxygen species-mediated p53 core-domain modifications determine apoptotic or necrotic death in cancer cells. Antioxidants & Redox Signaling. 16: 400-12. PMID 22145567 DOI: 10.1089/ars.2011.4103  0.36
2012 Khan M, Meduru S, Gogna R, Madan E, Citro L, Kuppusamy ML, Sayyid M, Mostafa M, Hamlin RL, Kuppusamy P. Oxygen cycling in conjunction with stem cell transplantation induces NOS3 expression leading to attenuation of fibrosis and improved cardiac function. Cardiovascular Research. 93: 89-99. PMID 22012955 DOI: 10.1093/Cvr/Cvr277  0.36
2011 Madan E, Gogna R, Bhatt M, Pati U, Kuppusamy P, Mahdi AA. Regulation of glucose metabolism by p53: emerging new roles for the tumor suppressor. Oncotarget. 2: 948-57. PMID 22248668  0.36
2011 Warwar N, Mor A, Fluhr R, Pandian RP, Kuppusamy P, Blank A. Detection and imaging of superoxide in roots by an electron spin resonance spin-probe method. Biophysical Journal. 101: 1529-38. PMID 21943435 DOI: 10.1016/j.bpj.2011.07.029  0.36
2011 Selvendiran K, Ahmed S, Dayton A, Kuppusamy ML, Rivera BK, Kálai T, Hideg K, Kuppusamy P. HO-3867, a curcumin analog, sensitizes cisplatin-resistant ovarian carcinoma, leading to therapeutic synergy through STAT3 inhibition. Cancer Biology & Therapy. 12: 837-45. PMID 21885917 DOI: 10.4161/cbt.12.9.17713  0.36
2011 Dayton A, Selvendiran K, Meduru S, Khan M, Kuppusamy ML, Naidu S, Kálai T, Hideg K, Kuppusamy P. Amelioration of doxorubicin-induced cardiotoxicity by an anticancer-antioxidant dual-function compound, HO-3867. The Journal of Pharmacology and Experimental Therapeutics. 339: 350-7. PMID 21799049 DOI: 10.1124/jpet.111.183681  0.36
2011 Naushad SM, Reddy CA, Rupasree Y, Pavani A, Digumarti RR, Gottumukkala SR, Kuppusamy P, Kutala VK. Cross-talk between one-carbon metabolism and xenobiotic metabolism: implications on oxidative DNA damage and susceptibility to breast cancer. Cell Biochemistry and Biophysics. 61: 715-23. PMID 21792634 DOI: 10.1007/s12013-011-9245-x  0.32
2011 Kálai T, Kuppusamy ML, Balog M, Selvendiran K, Rivera BK, Kuppusamy P, Hideg K. Synthesis of N-substituted 3,5-bis(arylidene)-4-piperidones with high antitumor and antioxidant activity. Journal of Medicinal Chemistry. 54: 5414-21. PMID 21702507 DOI: 10.1021/jm200353f  0.36
2011 Mundy-Bosse BL, Lesinski GB, Jaime-Ramirez AC, Benninger K, Khan M, Kuppusamy P, Guenterberg K, Kondadasula SV, Chaudhury AR, La Perle KM, Kreiner M, Young G, Guttridge DC, Carson WE. Myeloid-derived suppressor cell inhibition of the IFN response in tumor-bearing mice. Cancer Research. 71: 5101-10. PMID 21680779 DOI: 10.1158/0008-5472.CAN-10-2670  0.36
2011 Elnakish MT, Awad MM, Hassona MD, Alhaj MA, Kulkarni A, Citro LA, Sayyid M, Abouelnaga ZA, El-Sayed O, Kuppusamy P, Moldovan L, Khan M, Hassanain HH. Cardiac remodeling caused by transgenic overexpression of a corn Rac gene. American Journal of Physiology. Heart and Circulatory Physiology. 301: H868-80. PMID 21622832 DOI: 10.1152/Ajpheart.00807.2010  0.36
2011 Nishijima Y, Sridhar A, Bonilla I, Velayutham M, Khan M, Terentyeva R, Li C, Kuppusamy P, Elton TS, Terentyev D, Györke S, Zweier JL, Cardounel AJ, Carnes CA. Tetrahydrobiopterin depletion and NOS2 uncoupling contribute to heart failure-induced alterations in atrial electrophysiology. Cardiovascular Research. 91: 71-9. PMID 21460065 DOI: 10.1093/cvr/cvr087  0.36
2011 Khan M, Meduru S, Pandian RP, Rivera BK, Kuppusamy P. Effect of oxygenation on stem-cell therapy for myocardial infarction. Advances in Experimental Medicine and Biology. 701: 175-81. PMID 21445785 DOI: 10.1007/978-1-4419-7756-4_24  0.36
2011 Fisher E, Khan M, Steiner R, Kuppusamy P. Challenges to intestinal pOâ‚‚ measurement using EPR. Advances in Experimental Medicine and Biology. 701: 37-44. PMID 21445767 DOI: 10.1007/978-1-4419-7756-4_6  0.36
2011 Pandian RP, Chacko SM, Kuppusamy ML, Rivera BK, Kuppusamy P. Evaluation of lithium naphthalocyanine (LiNc) microcrystals for biological EPR oximetry. Advances in Experimental Medicine and Biology. 701: 29-36. PMID 21445766 DOI: 10.1007/978-1-4419-7756-4_5  0.36
2011 Ahmad R, Kuppusamy P. EPR Imaging: Theory and Instrumentation Multifrequency Electron Paramagnetic Resonance: Theory and Applications. 755-793. DOI: 10.1002/9783527633531.ch18  0.36
2010 Majumder S, Roy S, Kaffenberger T, Wang B, Costinean S, Frankel W, Bratasz A, Kuppusamy P, Hai T, Ghoshal K, Jacob ST. Loss of metallothionein predisposes mice to diethylnitrosamine-induced hepatocarcinogenesis by activating NF-kappaB target genes. Cancer Research. 70: 10265-76. PMID 21159647 DOI: 10.1158/0008-5472.Can-10-2839  0.36
2010 Chacko SM, Ahmed S, Selvendiran K, Kuppusamy ML, Khan M, Kuppusamy P. Hypoxic preconditioning induces the expression of prosurvival and proangiogenic markers in mesenchymal stem cells. American Journal of Physiology. Cell Physiology. 299: C1562-70. PMID 20861473 DOI: 10.1152/Ajpcell.00221.2010  0.36
2010 Dayton A, Selvendiran K, Kuppusamy ML, Rivera BK, Meduru S, Kálai T, Hideg K, Kuppusamy P. Cellular uptake, retention and bioabsorption of HO-3867, a fluorinated curcumin analog with potential antitumor properties. Cancer Biology & Therapy. 10: 1027-32. PMID 20798598 DOI: 10.4161/cbt.10.10.13250  0.36
2010 Jayachandran KS, Khan M, Selvendiran K, Devaraj SN, Kuppusamy P. Crataegus oxycantha extract attenuates apoptotic incidence in myocardial ischemia-reperfusion injury by regulating Akt and HIF-1 signaling pathways. Journal of Cardiovascular Pharmacology. 56: 526-31. PMID 20729753 DOI: 10.1097/FJC.0b013e3181f64c51  0.36
2010 Selvendiran K, Ahmed S, Dayton A, Ravi Y, Kuppusamy ML, Bratasz A, Rivera BK, Kálai T, Hideg K, Kuppusamy P. HO-3867, a synthetic compound, inhibits the migration and invasion of ovarian carcinoma cells through downregulation of fatty acid synthase and focal adhesion kinase. Molecular Cancer Research : McR. 8: 1188-97. PMID 20713491 DOI: 10.1158/1541-7786.MCR-10-0201  0.36
2010 Khan M, Kwiatkowski P, Rivera BK, Kuppusamy P. Oxygen and oxygenation in stem-cell therapy for myocardial infarction. Life Sciences. 87: 269-74. PMID 20600148 DOI: 10.1016/j.lfs.2010.06.013  0.36
2010 Selvendiran K, Kuppusamy ML, Ahmed S, Bratasz A, Meenakshisundaram G, Rivera BK, Khan M, Kuppusamy P. Oxygenation inhibits ovarian tumor growth by downregulating STAT3 and cyclin-D1 expressions. Cancer Biology & Therapy. 10: 386-90. PMID 20562529 DOI: 10.4161/cbt.10.4.12448  0.36
2010 Selvendiran K, Tong L, Bratasz A, Kuppusamy ML, Ahmed S, Ravi Y, Trigg NJ, Rivera BK, Kálai T, Hideg K, Kuppusamy P. Anticancer efficacy of a difluorodiarylidenyl piperidone (HO-3867) in human ovarian cancer cells and tumor xenografts. Molecular Cancer Therapeutics. 9: 1169-79. PMID 20442315 DOI: 10.1158/1535-7163.MCT-09-1207  0.36
2010 Meenakshisundaram G, Eteshola E, Blank A, Lee SC, Kuppusamy P. A molecular paramagnetic spin-doped biopolymeric oxygen sensor. Biosensors & Bioelectronics. 25: 2283-9. PMID 20371170 DOI: 10.1016/j.bios.2010.03.011  0.36
2010 Bognár B, Ahmed S, Kuppusamy ML, Selvendiran K, Khan M, Jeko J, Hankovszky OH, Kálai T, Kuppusamy P, Hideg K. Synthesis and study of new paramagnetic and diamagnetic verapamil derivatives. Bioorganic & Medicinal Chemistry. 18: 2954-63. PMID 20347319 DOI: 10.1016/j.bmc.2010.02.040  0.36
2010 Biswas S, Roy S, Banerjee J, Hussain SR, Khanna S, Meenakshisundaram G, Kuppusamy P, Friedman A, Sen CK. Hypoxia inducible microRNA 210 attenuates keratinocyte proliferation and impairs closure in a murine model of ischemic wounds. Proceedings of the National Academy of Sciences of the United States of America. 107: 6976-81. PMID 20308562 DOI: 10.1073/pnas.1001653107  0.36
2010 Ahmad R, Kuppusamy P. Theory, instrumentation, and applications of electron paramagnetic resonance oximetry. Chemical Reviews. 110: 3212-36. PMID 20218670 DOI: 10.1021/cr900396q  0.36
2010 Khan M, Meduru S, Mostafa M, Khan S, Hideg K, Kuppusamy P. Trimetazidine, administered at the onset of reperfusion, ameliorates myocardial dysfunction and injury by activation of p38 mitogen-activated protein kinase and Akt signaling. The Journal of Pharmacology and Experimental Therapeutics. 333: 421-9. PMID 20167841 DOI: 10.1124/jpet.109.165175  0.32
2010 Selvendiran K, Ahmed S, Dayton A, Kuppusamy ML, Tazi M, Bratasz A, Tong L, Rivera BK, Kálai T, Hideg K, Kuppusamy P. Safe and targeted anticancer efficacy of a novel class of antioxidant-conjugated difluorodiarylidenyl piperidones: differential cytotoxicity in healthy and cancer cells. Free Radical Biology & Medicine. 48: 1228-35. PMID 20156552 DOI: 10.1016/j.freeradbiomed.2010.02.009  0.36
2010 Rink C, Roy S, Khan M, Ananth P, Kuppusamy P, Sen CK, Khanna S. Oxygen-sensitive outcomes and gene expression in acute ischemic stroke. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 30: 1275-87. PMID 20145654 DOI: 10.1038/jcbfm.2010.7  0.36
2010 Pandian RP, Meenakshisundaram G, Bratasz A, Eteshola E, Lee SC, Kuppusamy P. An implantable Teflon chip holding lithium naphthalocyanine microcrystals for secure, safe, and repeated measurements of pO2 in tissues. Biomedical Microdevices. 12: 381-7. PMID 20058084 DOI: 10.1007/s10544-009-9394-5  0.36
2010 Blank A, Halevy R, Shklyar M, Shtirberg L, Kuppusamy P. ESR micro-imaging of LiNc-BuO crystals in PDMS: spatial and spectral grain distribution. Journal of Magnetic Resonance (San Diego, Calif. : 1997). 203: 150-5. PMID 20045659 DOI: 10.1016/j.jmr.2009.12.011  0.36
2010 Vikram DS, Rivera BK, Kuppusamy P. In vivo imaging of free radicals and oxygen. Methods in Molecular Biology (Clifton, N.J.). 610: 3-27. PMID 20013169 DOI: 10.1007/978-1-60327-029-8_1  0.36
2010 Meenakshisundaram G, Pandian RP, Eteshola E, Lee SC, Kuppusamy P. A paramagnetic implant containing lithium naphthalocyanine microcrystals for high-resolution biological oximetry. Journal of Magnetic Resonance (San Diego, Calif. : 1997). 203: 185-9. PMID 20006529 DOI: 10.1016/j.jmr.2009.11.016  0.36
2010 Wang F, Li Z, Khan M, Tamama K, Kuppusamy P, Wagner WR, Sen CK, Guan J. Injectable, rapid gelling and highly flexible hydrogel composites as growth factor and cell carriers. Acta Biomaterialia. 6: 1978-91. PMID 20004745 DOI: 10.1016/J.Actbio.2009.12.011  0.32
2010 Wang J, Dang V, Zhao W, Lu D, Rivera BK, Villamena FA, Wang PG, Kuppusamy P. Perchlorotrityl radical-fluorophore conjugates as dual fluorescence and EPR probes for superoxide radical anion. Bioorganic & Medicinal Chemistry. 18: 922-9. PMID 19963389 DOI: 10.1016/j.bmc.2009.11.034  0.36
2010 Sliman SM, Eubank TD, Kotha SR, Kuppusamy ML, Sherwani SI, Butler ES, Kuppusamy P, Roy S, Marsh CB, Stern DM, Parinandi NL. Hyperglycemic oxoaldehyde, glyoxal, causes barrier dysfunction, cytoskeletal alterations, and inhibition of angiogenesis in vascular endothelial cells: aminoguanidine protection. Molecular and Cellular Biochemistry. 333: 9-26. PMID 19585224 DOI: 10.1007/s11010-009-0199-x  0.36
2010 Ahmad R, Kuppusamy P, Potter LC. Nested uniform sampling for multiresolution 3-D tomography Icassp, Ieee International Conference On Acoustics, Speech and Signal Processing - Proceedings. 461-464. DOI: 10.1109/ICASSP.2010.5495713  0.36
2010 Pandian RP, Raju NP, Gallucci JC, Woodward PM, Epstein AJ, Kuppusamy P. A new tetragonal crystalline polymorph of lithium octa-n-butoxy- naphthalocyanine (LiNc-BuO) radical: Structural, magnetic and oxygen-sensing properties Chemistry of Materials. 22: 6254-6262. DOI: 10.1021/Cm101733H  0.36
2009 Lakshmi SV, Padmaja G, Kuppusamy P, Kutala VK. Oxidative stress in cardiovascular disease. Indian Journal of Biochemistry & Biophysics. 46: 421-40. PMID 20361706  0.36
2009 Pandian RP, Dolgos M, Marginean C, Woodward PM, Hammel PC, Manoharan PT, Kuppusamy P. Molecular packing and magnetic properties of lithium naphthalocyanine crystals: hollow channels enabling permeability and paramagnetic sensitivity to molecular oxygen. Journal of Materials Chemistry. 19: 4138-4147. PMID 19809598 DOI: 10.1039/B901886G  0.36
2009 Das H, George JC, Joseph M, Das M, Abdulhameed N, Blitz A, Khan M, Sakthivel R, Mao HQ, Hoit BD, Kuppusamy P, Pompili VJ. Stem cell therapy with overexpressed VEGF and PDGF genes improves cardiac function in a rat infarct model. Plos One. 4: e7325. PMID 19809493 DOI: 10.1371/journal.pone.0007325  0.32
2009 Selvendiran K, Bratasz A, Kuppusamy ML, Tazi MF, Rivera BK, Kuppusamy P. Hypoxia induces chemoresistance in ovarian cancer cells by activation of signal transducer and activator of transcription 3. International Journal of Cancer. 125: 2198-204. PMID 19623660 DOI: 10.1002/ijc.24601  0.36
2009 Peltz A, Sherwani SI, Kotha SR, Mazerik JN, O'Connor Butler ES, Kuppusamy ML, Hagele T, Magalang UJ, Kuppusamy P, Marsh CB, Parinandi NL. Calcium and calmodulin regulate mercury-induced phospholipase D activation in vascular endothelial cells. International Journal of Toxicology. 28: 190-206. PMID 19546257 DOI: 10.1177/1091581809338077  0.36
2009 Khan M, Meduru S, Mohan IK, Kuppusamy ML, Wisel S, Kulkarni A, Rivera BK, Hamlin RL, Kuppusamy P. Hyperbaric oxygenation enhances transplanted cell graft and functional recovery in the infarct heart. Journal of Molecular and Cellular Cardiology. 47: 275-87. PMID 19376124 DOI: 10.1016/J.Yjmcc.2009.04.005  0.36
2009 Meenakshisundaram G, Eteshola E, Pandian RP, Bratasz A, Selvendiran K, Lee SC, Krishna MC, Swartz HM, Kuppusamy P. Oxygen sensitivity and biocompatibility of an implantable paramagnetic probe for repeated measurements of tissue oxygenation. Biomedical Microdevices. 11: 817-26. PMID 19319683 DOI: 10.1007/S10544-009-9298-4  0.36
2009 Meenakshisundaram G, Eteshola E, Pandian RP, Bratasz A, Lee SC, Kuppusamy P. Fabrication and physical evaluation of a polymer-encapsulated paramagnetic probe for biomedical oximetry. Biomedical Microdevices. 11: 773-82. PMID 19291409 DOI: 10.1007/s10544-009-9292-x  0.36
2009 Chacko SM, Khan M, Kuppusamy ML, Pandian RP, Varadharaj S, Selvendiran K, Bratasz A, Rivera BK, Kuppusamy P. Myocardial oxygenation and functional recovery in infarct rat hearts transplanted with mesenchymal stem cells. American Journal of Physiology. Heart and Circulatory Physiology. 296: H1263-73. PMID 19286938 DOI: 10.1152/Ajpheart.01311.2008  0.36
2009 Selvendiran K, Kuppusamy ML, Bratasz A, Tong L, Rivera BK, Rink C, Sen CK, Kálai T, Hideg K, Kuppusamy P. Inhibition of vascular smooth-muscle cell proliferation and arterial restenosis by HO-3867, a novel synthetic curcuminoid, through up-regulation of PTEN expression. The Journal of Pharmacology and Experimental Therapeutics. 329: 959-66. PMID 19276401 DOI: 10.1124/jpet.108.150367  0.36
2009 Eubank TD, Roberts RD, Khan M, Curry JM, Nuovo GJ, Kuppusamy P, Marsh CB. Granulocyte macrophage colony-stimulating factor inhibits breast cancer growth and metastasis by invoking an anti-angiogenic program in tumor-educated macrophages. Cancer Research. 69: 2133-40. PMID 19223554 DOI: 10.1158/0008-5472.CAN-08-1405  0.36
2009 Wisel S, Khan M, Kuppusamy ML, Mohan IK, Chacko SM, Rivera BK, Sun BC, Hideg K, Kuppusamy P. Pharmacological preconditioning of mesenchymal stem cells with trimetazidine (1-[2,3,4-trimethoxybenzyl]piperazine) protects hypoxic cells against oxidative stress and enhances recovery of myocardial function in infarcted heart through Bcl-2 expression. The Journal of Pharmacology and Experimental Therapeutics. 329: 543-50. PMID 19218529 DOI: 10.1124/Jpet.109.150839  0.36
2009 Carsillo M, Kutala VK, Puschel K, Blanco J, Kuppusamy P, Niewiesk S. Nitric oxide production and nitric oxide synthase type 2 expression by cotton rat (Sigmodon hispidus) macrophages reflect the same pattern as human macrophages. Developmental and Comparative Immunology. 33: 718-24. PMID 19154756 DOI: 10.1016/j.dci.2008.12.004  0.32
2009 Eteshola E, Pandian RP, Lee SC, Kuppusamy P. Polymer coating of paramagnetic particulates for in vivo oxygen-sensing applications. Biomedical Microdevices. 11: 379-87. PMID 19083100 DOI: 10.1007/s10544-008-9244-x  0.36
2009 Mohan IK, Khan M, Wisel S, Selvendiran K, Sridhar A, Carnes CA, Bognar B, Kálai T, Hideg K, Kuppusamy P. Cardioprotection by HO-4038, a novel verapamil derivative, targeted against ischemia and reperfusion-mediated acute myocardial infarction. American Journal of Physiology. Heart and Circulatory Physiology. 296: H140-51. PMID 18978191 DOI: 10.1152/ajpheart.00687.2008  0.32
2009 Khan M, Mohan IK, Kutala VK, Kotha SR, Parinandi NL, Hamlin RL, Kuppusamy P. Sulfaphenazole protects heart against ischemia-reperfusion injury and cardiac dysfunction by overexpression of iNOS, leading to enhancement of nitric oxide bioavailability and tissue oxygenation. Antioxidants & Redox Signaling. 11: 725-38. PMID 18855521 DOI: 10.1089/Ars.2008.2155  0.36
2008 Som S, Potter LC, Ahmad R, Vikram DS, Kuppusamy P. EPR oximetry in three spatial dimensions using sparse spin distribution. Journal of Magnetic Resonance (San Diego, Calif. : 1997). 193: 210-7. PMID 18538600 DOI: 10.1016/J.Jmr.2008.05.004  0.36
2008 Vikram DS, Ahmad R, Pandian RP, Petryakov S, Kuppusamy P. Evaluation of oxygen-response times of phthalocyanine-based crystalline paramagnetic spin probes for EPR oximetry. Journal of Magnetic Resonance (San Diego, Calif. : 1997). 193: 127-32. PMID 18479953 DOI: 10.1016/J.Jmr.2008.04.034  0.36
2008 Roshchupkina GI, Bobko AA, Bratasz A, Reznikov VA, Kuppusamy P, Khramtsov VV. In vivo EPR measurement of glutathione in tumor-bearing mice using improved disulfide biradical probe. Free Radical Biology & Medicine. 45: 312-20. PMID 18468522 DOI: 10.1016/j.freeradbiomed.2008.04.019  0.36
2008 Ahmad R, Vikram DS, Potter LC, Kuppusamy P. Estimation of mean and median pO2 values for a composite EPR spectrum. Journal of Magnetic Resonance (San Diego, Calif. : 1997). 192: 269-74. PMID 18362081 DOI: 10.1016/J.Jmr.2008.03.002  0.36
2008 Bratasz A, Selvendiran K, Wasowicz T, Bobko A, Khramtsov VV, Ignarro LJ, Kuppusamy P. NCX-4040, a nitric oxide-releasing aspirin, sensitizes drug-resistant human ovarian xenograft tumors to cisplatin by depletion of cellular thiols. Journal of Translational Medicine. 6: 9. PMID 18302761 DOI: 10.1186/1479-5876-6-9  0.36
2008 Khan M, Kutala VK, Wisel S, Chacko SM, Kuppusamy ML, Kwiatkowski P, Kuppusamy P. Measurement of oxygenation at the site of stem cell therapy in a murine model of myocardial infarction. Advances in Experimental Medicine and Biology. 614: 45-52. PMID 18290313 DOI: 10.1007/978-0-387-74911-2_6  0.36
2008 Selvendiran K, Bratasz A, Tong L, Ignarro LJ, Kuppusamy P. NCX-4016, a nitro-derivative of aspirin, inhibits EGFR and STAT3 signaling and modulates Bcl-2 proteins in cisplatin-resistant human ovarian cancer cells and xenografts Cell Cycle. 7: 81-88. PMID 18196976 DOI: 10.4161/Cc.7.1.5103  0.36
2008 Hussain SR, Lucas DM, Johnson AJ, Lin TS, Bakaletz AP, Dang VX, Viatchenko-Karpinski S, Ruppert AS, Byrd JC, Kuppusamy P, Crouser ED, Grever MR. Flavopiridol causes early mitochondrial damage in chronic lymphocytic leukemia cells with impaired oxygen consumption and mobilization of intracellular calcium. Blood. 111: 3190-9. PMID 18192508 DOI: 10.1182/blood-2007-10-115733  0.36
2008 Kutala VK, Villamena FA, Ilangovan G, Maspoch D, Roques N, Veciana J, Rovira C, Kuppusamy P. Reactivity of superoxide anion radical with a perchlorotriphenylmethyl (trityl) radical. The Journal of Physical Chemistry. B. 112: 158-67. PMID 18081340 DOI: 10.1021/jp076656x  0.32
2008 Kuppusamy P, Blank A. Foreword by the guest editors Israel Journal of Chemistry. 48. DOI: 10.1560/IJC.48.1.i  0.36
2008 Vikram DS, Ahmad R, Rivera BK, Kuppusamy P. Mapping of oxygen concentration in biological samples using EPR imaging Israel Journal of Chemistry. 48: 39-43. DOI: 10.1560/IJC.48.1.39  0.36
2008 Savla M, Pandian RP, Kuppusamy P, Agarwal G. Magnetic force microscopy of an oxygen-sensing spin-probe Israel Journal of Chemistry. 48: 33-38. DOI: 10.1560/Ijc.48.1.33  0.36
2008 Kulkarni AC, Bratasz A, Rivera B, Krishna MC, Kuppusamy P. Redox mapping of biological samples using EPR imaging Israel Journal of Chemistry. 48: 27-31. DOI: 10.1560/IJC.48.1.27  0.36
2007 Mazerik JN, Hagele T, Sherwani S, Ciapala V, Butler S, Kuppusamy ML, Hunter M, Kuppusamy P, Marsh CB, Parinandi NL. Phospholipase A2 activation regulates cytotoxicity of methylmercury in vascular endothelial cells. International Journal of Toxicology. 26: 553-69. PMID 18066971 DOI: 10.1080/10915810701707759  0.36
2007 Khan M, Mohan IK, Kutala VK, Kumbala D, Kuppusamy P. Cardioprotection by sulfaphenazole, a cytochrome p450 inhibitor: mitigation of ischemia-reperfusion injury by scavenging of reactive oxygen species. The Journal of Pharmacology and Experimental Therapeutics. 323: 813-21. PMID 17873104 DOI: 10.1124/jpet.107.129486  0.36
2007 Kulkarni AC, Kuppusamy P, Parinandi N. Oxygen, the lead actor in the pathophysiologic drama: enactment of the trinity of normoxia, hypoxia, and hyperoxia in disease and therapy. Antioxidants & Redox Signaling. 9: 1717-30. PMID 17822371 DOI: 10.1089/Ars.2007.1724  0.36
2007 Parinandi NL, Sharma A, Eubank TD, Kaufman BF, Kutala VK, Marsh CB, Ignarro LJ, Kuppusamy P. Nitroaspirin (NCX-4016), an NO donor, is antiangiogenic through induction of loss of redox-dependent viability and cytoskeletal reorganization in endothelial cells Antioxidants and Redox Signaling. 9: 1837-1849. PMID 17760507 DOI: 10.1089/Ars.2007.1603  0.36
2007 Vikram DS, Bratasz A, Ahmad R, Kuppusamy P. A comparative evaluation of EPR and OxyLite oximetry using a random sampling of pO(2) in a murine tumor. Radiation Research. 168: 308-15. PMID 17705635 DOI: 10.1667/Rr0854.1  0.36
2007 Vikram DS, Zweier JL, Kuppusamy P. Methods for noninvasive imaging of tissue hypoxia Antioxidants and Redox Signaling. 9: 1745-1756. PMID 17663644 DOI: 10.1089/Ars.2007.1717  0.36
2007 Khan M, Kutala VK, Vikram DS, Wisel S, Chacko SM, Kuppusamy ML, Mohan IK, Zweier JL, Kwiatkowski P, Kuppusamy P. Skeletal myoblasts transplanted in the ischemic myocardium enhance in situ oxygenation and recovery of contractile function. American Journal of Physiology. Heart and Circulatory Physiology. 293: H2129-39. PMID 17660391 DOI: 10.1152/Ajpheart.00677.2007  0.36
2007 Kutala VK, Khan M, Angelos MG, Kuppusamy P. Role of oxygen in postischemic myocardial injury. Antioxidants & Redox Signaling. 9: 1193-206. PMID 17571958 DOI: 10.1089/Ars.2007.1636  0.36
2007 Ahmad R, Vikram DS, Clymer B, Potter LC, Deng Y, Srinivasan P, Zweier JL, Kuppusamy P. Uniform distribution of projection data for improved reconstruction quality of 4D EPR imaging. Journal of Magnetic Resonance (San Diego, Calif. : 1997). 187: 277-87. PMID 17562375 DOI: 10.1016/J.Jmr.2007.05.012  0.36
2007 Butt OI, Carruth R, Kutala VK, Kuppusamy P, Moldovan NI. Stimulation of peri-implant vascularization with bone marrow-derived progenitor cells: monitoring by in vivo EPR oximetry. Tissue Engineering. 13: 2053-61. PMID 17518714 DOI: 10.1089/ten.2006.0225  0.36
2007 Falk JA, Aune SE, Kutala VK, Kuppusamy P, Angelos MG. Inhibition of peroxynitrite precursors, NO and O2, at the onset of reperfusion improves myocardial recovery. Resuscitation. 74: 508-15. PMID 17418932 DOI: 10.1016/J.Resuscitation.2007.01.026  0.36
2007 Hagele TJ, Mazerik JN, Gregory A, Kaufman B, Magalang U, Kuppusamy ML, Marsh CB, Kuppusamy P, Parinandi NL. Mercury activates vascular endothelial cell phospholipase D through thiols and oxidative stress. International Journal of Toxicology. 26: 57-69. PMID 17365148 DOI: 10.1080/10915810601120509  0.36
2007 Som S, Potter LC, Ahmad R, Kuppusamy P. A parametric approach to spectral-spatial EPR imaging. Journal of Magnetic Resonance (San Diego, Calif. : 1997). 186: 1-10. PMID 17276111 DOI: 10.1016/j.jmr.2006.12.018  0.36
2007 Bratasz A, Kulkarni AC, Kuppusamy P. A highly sensitive biocompatible spin probe for imaging of oxygen concentration in tissues Biophysical Journal. 92: 2918-2925. PMID 17259268 DOI: 10.1529/Biophysj.106.099135  0.36
2007 Weir NM, Selvendiran K, Kutala VK, Tong L, Vishwanath S, Rajaram M, Tridandapani S, Anant S, Kuppusamy P. Curcumin induces G2/M arrest and apoptosis in cisplatin-resistant human ovarian cancer cells by modulating Akt and p38 MAPK Cancer Biology and Therapy. 6: 178-184. PMID 17218783 DOI: 10.4161/cbt.6.2.3577  0.36
2007 Wisel S, Chacko SM, Kuppusamy ML, Pandian RP, Khan M, Kutala VK, Burry RW, Sun B, Kwiatkowski P, Kuppusamy P. Labeling of skeletal myoblasts with a novel oxygen-sensing spin probe for noninvasive monitoring of in situ oxygenation and cell therapy in heart. American Journal of Physiology. Heart and Circulatory Physiology. 292: H1254-61. PMID 17142337 DOI: 10.1152/Ajpheart.01058.2006  0.36
2007 Ahmad R, Clymer B, Vikram DS, Deng Y, Hirata H, Zweier JL, Kuppusamy P. Enhanced resolution for EPR imaging by two-step deblurring. Journal of Magnetic Resonance (San Diego, Calif. : 1997). 184: 246-57. PMID 17113800 DOI: 10.1016/J.Jmr.2006.10.007  0.36
2007 Ahmad R, Deng Y, Vikram DS, Clymer B, Srinivasan P, Zweier JL, Kuppusamy P. Quasi Monte Carlo-based isotropic distribution of gradient directions for improved reconstruction quality of 3D EPR imaging. Journal of Magnetic Resonance (San Diego, Calif. : 1997). 184: 236-45. PMID 17095271 DOI: 10.1016/J.Jmr.2006.10.008  0.36
2007 Sostaric JZ, Pandian RP, Bratasz A, Kuppusamy P. Encapsulation of a highly sensitive EPR active oxygen probe into sonochemically prepared microspheres Journal of Physical Chemistry B. 111: 3298-3303. DOI: 10.1021/jp0682356  0.36
2007 Pandian RP, Dolgos M, Dang V, Sostaric JZ, Woodward PM, Kuppusamy P. Structure and oxygen-sensing paramagnetic properties of a new lithium 1,8,15,22-tetraphenoxyphthalocyanine radical probe for biological oximetry Chemistry of Materials. 19: 3545-3552. DOI: 10.1021/Cm070622K  0.36
2006 Magalang UJ, Rajappan R, Hunter MG, Kutala VK, Kuppusamy P, Wewers MD, Marsh CB, Parinandi NL. Adiponectin inhibits superoxide generation by human neutrophils. Antioxidants & Redox Signaling. 8: 2179-86. PMID 17034361 DOI: 10.1089/ars.2006.8.2179  0.32
2006 Kutala VK, Khan M, Mandal R, Potaraju V, Colantuono G, Kumbala D, Kuppusamy P. Prevention of postischemic myocardial reperfusion injury by the combined treatment of NCX-4016 and Tempol. Journal of Cardiovascular Pharmacology. 48: 79-87. PMID 17031260 DOI: 10.1097/01.fjc.0000242050.16790.65  0.36
2006 Presley T, Kuppusamy P, Zweier JL, Ilangovan G. Electron paramagnetic resonance oximetry as a quantitative method to measure cellular respiration: A consideration of oxygen diffusion interference Biophysical Journal. 91: 4623-4631. PMID 17012319 DOI: 10.1529/Biophysj.106.090175  0.36
2006 Xia S, Villamena FA, Hadad CM, Kuppusamy P, Li Y, Zhu H, Zweier JL. Reactivity of molecular oxygen with ethoxycarbonyl derivatives of tetrathiatriarylmethyl radicals. The Journal of Organic Chemistry. 71: 7268-79. PMID 16958520 DOI: 10.1021/Jo0610560  0.36
2006 Bratasz A, Pandian RP, Ilangovan G, Kuppusamy P. Monitoring oxygenation during the growth of a transplanted tumor Advances in Experimental Medicine and Biology. 578: 375-380. PMID 16927719 DOI: 10.1007/0-387-29540-2_58  0.36
2006 Parinandi NL, Sen CK, Kuppusamy P. Joint International Conference on EPR Spectroscopy and Wound Healing Antioxidants and Redox Signaling. 8: 1385-1387. PMID 16910786 DOI: 10.1089/ars.2006.8.1385  0.36
2006 Ahmad R, Vikram DS, Petryakov S, Deng Y, Zweier JL, Kuppusamy P, Clymer B. Automated on-the-fly detection and correction procedure for EPR imaging data acquisition. Magnetic Resonance in Medicine. 56: 644-53. PMID 16878301 DOI: 10.1002/Mrm.20967  0.36
2006 Deng Y, Pandian RP, Ahmad R, Kuppusamy P, Zweier JL. Application of magnetic field over-modulation for improved EPR linewidth measurements using probes with Lorentzian lineshape. Journal of Magnetic Resonance (San Diego, Calif. : 1997). 181: 254-61. PMID 16759891 DOI: 10.1016/j.jmr.2006.05.010  0.36
2006 Pandian RP, Dang V, Manoharan PT, Zweier JL, Kuppusamy P. Effect of nitrogen dioxide on the EPR property of lithium octa-n-butoxy 2,3-naphthalocyanine (LiNc-BuO) microcrystals. Journal of Magnetic Resonance (San Diego, Calif. : 1997). 181: 154-61. PMID 16690337 DOI: 10.1016/j.jmr.2006.04.004  0.36
2006 Deng Y, Shet K, Li H, Kuppusamy P, Zweier JL. Real-time calculation and visualization of spectra in field-cycled dynamic nuclear polarization spectroscopy. Computer Methods and Programs in Biomedicine. 82: 67-72. PMID 16563554 DOI: 10.1016/J.Cmpb.2006.02.002  0.36
2006 Ganesan LP, Joshi T, Fang H, Kutala VK, Roda J, Trotta R, Lehman A, Kuppusamy P, Byrd JC, Carson WE, Caligiuri MA, Tridandapani S. FcgammaR-induced production of superoxide and inflammatory cytokines is differentially regulated by SHIP through its influence on PI3K and/or Ras/Erk pathways. Blood. 108: 718-25. PMID 16543474 DOI: 10.1182/Blood-2005-09-3889  0.32
2006 Bratasz A, Weir NM, Parinandi NL, Zweier JL, Sridhar R, Ignarro LJ, Kuppusamy P. Reversal to cisplatin sensitivity in recurrent human ovarian cancer cells by NCX-4016, a nitro derivative of aspirin Proceedings of the National Academy of Sciences of the United States of America. 103: 3914-3919. PMID 16497833 DOI: 10.1073/Pnas.0511250103  0.36
2006 Kutala VK, Khan M, Mandal R, Ganesan LP, Tridandapani S, Kalai T, Hideg K, Kuppusamy P. Attenuation of myocardial ischemia-reperfusion injury by trimetazidine derivatives functionalized with antioxidant properties. The Journal of Pharmacology and Experimental Therapeutics. 317: 921-8. PMID 16467453 DOI: 10.1124/jpet.105.100834  0.32
2006 Li H, He G, Deng Y, Kuppusamy P, Zweier JL. In vivo proton electron double resonance imaging of the distribution and clearance of nitroxide radicals in mice. Magnetic Resonance in Medicine. 55: 669-75. PMID 16463344 DOI: 10.1002/Mrm.20804  0.36
2006 Ahmad R, Clymer B, Deng Y, He G, Vikram D, Kuppusamy P, Zweier JL. Optimization of data acquisition for EPR imaging. Journal of Magnetic Resonance (San Diego, Calif. : 1997). 179: 263-72. PMID 16458030 DOI: 10.1016/J.Jmr.2005.12.013  0.36
2006 Varadharaj S, Steinhour E, Hunter MG, Watkins T, Baran CP, Magalang U, Kuppusamy P, Zweier JL, Marsh CB, Natarajan V, Parinandi NL. Vitamin C-induced activation of phospholipase D in lung microvascular endothelial cells: regulation by MAP kinases. Cellular Signalling. 18: 1396-407. PMID 16376521 DOI: 10.1016/j.cellsig.2005.10.019  0.32
2006 Khan M, Varadharaj S, Ganesan LP, Shobha JC, Naidu MU, Parinandi NL, Tridandapani S, Kutala VK, Kuppusamy P. C-phycocyanin protects against ischemia-reperfusion injury of heart through involvement of p38 MAPK and ERK signaling. American Journal of Physiology. Heart and Circulatory Physiology. 290: H2136-45. PMID 16373583 DOI: 10.1152/ajpheart.01072.2005  0.32
2006 Ilangovan G, Venkatakrishnan CD, Bratasz A, Osinbowale S, Cardounel AJ, Zweier JL, Kuppusamy P. Heat shock-induced attenuation of hydroxyl radical generation and mitochondrial aconitase activity in cardiac H9c2 cells. American Journal of Physiology. Cell Physiology. 290: C313-24. PMID 16162655 DOI: 10.1152/ajpcell.00362.2005  0.32
2006 Angelos MG, Kutala VK, Torres CA, He G, Stoner JD, Mohammad M, Kuppusamy P. Hypoxic reperfusion of the ischemic heart and oxygen radical generation. American Journal of Physiology. Heart and Circulatory Physiology. 290: H341-7. PMID 16126819 DOI: 10.1152/Ajpheart.00223.2005  0.36
2006 Pandian RP, Kim YI, Woodward PM, Zweier JL, Manoharan PT, Kuppusamy P. The open molecular framework of paramagnetic lithium octabutoxy-naphthalocyanine: Implications for the detection of oxygen and nitric oxide using EPR spectroscopy Journal of Materials Chemistry. 16: 3609-3618. DOI: 10.1039/B517976A  0.36
2006 Sostaric JZ, Pandian RP, Weavers LK, Kuppusamy P. Formation of lithium phthalocyanine nanotubes by size reduction using low- and high-frequency ultrasound Chemistry of Materials. 18: 4183-4189. DOI: 10.1021/cm060751l  0.36
2005 Ilangovan G, Bratasz A, Kuppusamy P. Non-invasive measurement of tumor oxygenation using embedded microparticulate EPR spin probe Advances in Experimental Medicine and Biology. 566: 67-73. PMID 16594136 DOI: 10.1007/0-387-26206-7_10  0.36
2005 Pandian RP, Kutala VK, Liaugminas A, Parinandi NL, Kuppusamy P. Lipopolysaccharide-induced alterations in oxygen consumption and radical generation in endothelial cells Molecular and Cellular Biochemistry. 278: 119-127. PMID 16180097 DOI: 10.1007/s11010-005-6936-x  0.36
2005 Xu KY, Kuppusamy P. Dual effects of copper-zinc superoxide dismutase Biochemical and Biophysical Research Communications. 336: 1190-1193. PMID 16169521 DOI: 10.1016/j.bbrc.2005.08.249  0.36
2005 Fries RB, Wallace WA, Roy S, Kuppusamy P, Bergdall V, Gordillo GM, Melvin WS, Sen CK. Dermal excisional wound healing in pigs following treatment with topically applied pure oxygen. Mutation Research. 579: 172-81. PMID 16105672 DOI: 10.1016/j.mrfmmm.2005.02.023  0.36
2005 Deng Y, Kuppusamy P, Zweier JL. Progressive EPR imaging with adaptive projection acquisition Journal of Magnetic Resonance. 174: 177-187. PMID 15862233 DOI: 10.1016/j.jmr.2005.01.019  0.36
2005 Varadharaj S, Watkins T, Cardounel AJ, Garcia JG, Zweier JL, Kuppusamy P, Natarajan V, Parinandi NL. Vitamin C-induced loss of redox-dependent viability in lung microvascular endothelial cells. Antioxidants & Redox Signaling. 7: 287-300. PMID 15650416 DOI: 10.1089/ars.2005.7.287  0.32
2004 Ilangovan G, Osinbowale S, Bratasz A, Bonar M, Cardounel AJ, Zweier JL, Kuppusamy P. Heat shock regulates the respiration of cardiac H9c2 cells through upregulation of nitric oxide synthase. American Journal of Physiology. Cell Physiology. 287: C1472-81. PMID 15475520 DOI: 10.1152/ajpcell.00103.2004  0.32
2004 Samouilov A, Roubaud V, Kuppusamy P, Zweier JL. Kinetic analysis-based quantitation of free radical generation in EPR spin trapping Analytical Biochemistry. 334: 145-154. PMID 15464963 DOI: 10.1016/j.ab.2004.07.026  0.36
2004 Kuppusamy P, Zweier JL. Cardiac applications of EPR imaging Nmr in Biomedicine. 17: 226-239. PMID 15366025 DOI: 10.1002/nbm.912  0.36
2004 Ilangovan G, Bratasz A, Li H, Schmalbrock P, Zweier JL, Kuppusamy P. In vivo measurement and imaging of tumor oxygenation using coembedded paramagnetic particulates. Magnetic Resonance in Medicine. 52: 650-7. PMID 15334586 DOI: 10.1002/Mrm.20188  0.36
2004 Ilangovan G, Zweier JL, Kuppusamy P. Mechanism of oxygen-induced EPR line broadening in lithium phthalocyanine microcrystals Journal of Magnetic Resonance. 170: 42-48. PMID 15324756 DOI: 10.1016/j.jmr.2004.05.018  0.36
2004 Crowther JE, Kutala VK, Kuppusamy P, Ferguson JS, Beharka AA, Zweier JL, McCormack FX, Schlesinger LS. Pulmonary surfactant protein a inhibits macrophage reactive oxygen intermediate production in response to stimuli by reducing NADPH oxidase activity. Journal of Immunology (Baltimore, Md. : 1950). 172: 6866-74. PMID 15153505  0.36
2004 Deng Y, He G, Petryakov S, Kuppusamy P, Zweier JL. Fast EPR imaging at 300 MHz using spinning magnetic field gradients Journal of Magnetic Resonance. 168: 220-227. PMID 15140431 DOI: 10.1016/j.jmr.2004.02.012  0.36
2004 Kutala VK, Parinandi NL, Pandian RP, Kuppusamy P. Simultaneous Measurement of Oxygenation in Intracellular and Extracellular Compartments of Lung Microvascular Endothelial Cells Antioxidants and Redox Signaling. 6: 597-603. PMID 15130286  0.36
2004 Kuppusamy P. EPR Spectroscopy in Biology and Medicine Antioxidants and Redox Signaling. 6: 583-585. PMID 15130284  0.36
2004 Ilangovan G, Zweier JL, Kuppusamy P. Microximetry: Simultaneous Determination of Oxygen Consumption and Free Radical Production Using Electron Paramagnetic Resonance Spectroscopy Methods in Enzymology. 381: 747-762. PMID 15063710 DOI: 10.1016/S0076-6879(04)81048-6  0.36
2004 Kutala VK, Parinandi NL, Zweier JL, Kuppusamy P. Reaction of superoxide with trityl radical: Implications for the determination of superoxide by spectrophotometry Archives of Biochemistry and Biophysics. 424: 81-88. PMID 15019839 DOI: 10.1016/j.abb.2004.01.020  0.36
2004 He G, Kutala VK, Kuppusamy P, Zweier JL. In vivo measurement and mapping of skin redox stress induced by ultraviolet light exposure Free Radical Biology and Medicine. 36: 665-672. PMID 14980709 DOI: 10.1016/j.freeradbiomed.2003.11.024  0.36
2003 Pandian RP, Kutala VK, Parinandi NL, Zweier JL, Kuppusamy P. Measurement of oxygen consumption in mouse aortic endothelial cells using a microparticulate oximetry probe Archives of Biochemistry and Biophysics. 420: 169-175. PMID 14622987 DOI: 10.1016/j.abb.2003.09.008  0.36
2003 Pandian RP, Parinandi NL, Ilangovan G, Zweier JL, Kuppusamy P. Novel particulate spin probe for targeted determination of oxygen in cells and tissues Free Radical Biology and Medicine. 35: 1138-1148. PMID 14572616 DOI: 10.1016/S0891-5849(03)00496-9  0.36
2003 Zweier JL, He G, Samouilov A, Kuppusamy P. EPR spectroscopy and imaging of oxygen: Applications to the gastrointestinal tract Advances in Experimental Medicine and Biology. 530: 123-131. PMID 14562710 DOI: 10.1007/978-1-4615-0075-9_12  0.36
2003 Xu KY, Kuppusamy SP, Wang JQ, Li H, Cui H, Dawson TM, Huang PL, Burnett AL, Kuppusamy P, Becker LC. Nitric oxide protects cardiac sarcolemmal membrane enzyme function and ion active transport against ischemia-induced inactivation. The Journal of Biological Chemistry. 278: 41798-803. PMID 12904295 DOI: 10.1074/Jbc.M306865200  0.36
2003 Deng Y, He G, Kuppusamy P, Zweier JL. Deconvolution algorithm based on automatic cutoff frequency selection for EPR imaging Magnetic Resonance in Medicine. 50: 444-448. PMID 12876725 DOI: 10.1002/mrm.10533  0.36
2003 Velayutham M, Li H, Kuppusamy P, Zweier JL. Mapping ischemic risk region and necrosis in the isolated heart using EPR imaging Magnetic Resonance in Medicine. 49: 1181-1187. PMID 12768597 DOI: 10.1002/mrm.10473  0.36
2003 Liu JQ, Sham JSK, Shimoda LA, Kuppusamy P, Sylvester JT. Hypoxic constriction and reactive oxygen species in porcine distal pulmonary arteries American Journal of Physiology - Lung Cellular and Molecular Physiology. 285. PMID 12665465  0.36
2003 Ilangovan G, Li H, Zweier JL, Kuppusamy P. Effect of carbogen-breathing on redox status of the RIF-1 tumor Advances in Experimental Medicine and Biology. 510: 13-17. PMID 12580398  0.36
2002 Li H, Deng Y, He G, Kuppusamy P, Lurie DJ, Zweier JL. Proton electron double resonance imaging of the in vivo distribution and clearance of a triaryl methyl radical in mice. Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine. 48: 530-4. PMID 12210919 DOI: 10.1002/mrm.10222  0.36
2002 Ilangovan G, Li H, Zweier JL, Kuppusamy P. In vivo measurement of tumor redox environment using EPR spectroscopy Molecular and Cellular Biochemistry. 234: 393-398. PMID 12162459 DOI: 10.1023/A:1015967305659  0.36
2002 He G, Samouilov A, Kuppusamy P, Zweier JL. In vivo imaging of free radicals: Applications from mouse to man Molecular and Cellular Biochemistry. 234: 359-367. PMID 12162454 DOI: 10.1023/A:1015994629341  0.36
2002 Li Y, Seacat A, Kuppusamy P, Zweier JL, Yager JD, Trush MA. Copper redox-dependent activation of 2-tert-butyl(1,4)hydroquinone: formation of reactive oxygen species and induction of oxidative DNA damage in isolated DNA and cultured rat hepatocytes. Mutation Research. 518: 123-33. PMID 12113763  0.36
2002 Li H, Ma L, Hsia CJC, Zweier JL, Kuppusamy P. Polynitroxyl-albumin (PNA) enhances myocardial infarction therapeutic effect of Tempol in rat hearts subjected to regional ischemia-reperfusion Free Radical Biology and Medicine. 32: 712-719. PMID 11937297 DOI: 10.1016/S0891-5849(02)00762-1  0.36
2002 He G, Deng Y, Li H, Kuppusamy P, Zweier JL. EPR/NMR co-imaging for anatomic registration of free-radical images. Magnetic Resonance in Medicine. 47: 571-8. PMID 11870845 DOI: 10.1002/mrm.10077  0.36
2002 Souza HP, Liu X, Samouilov A, Kuppusamy P, Laurindo FRM, Zweier JL. Quantitation of superoxide generation and substrate utilization by vascular NAD(P)H oxidase American Journal of Physiology - Heart and Circulatory Physiology. 282. PMID 11788393  0.36
2002 Ilangovan G, Pal R, Zweier JL, Kuppusamy P. Electrochemical preparation and EPR studies of lithium phthalocyanine. 4. Effect of nitric oxide Journal of Physical Chemistry B. 106: 11929-11935. DOI: 10.1021/jp026360l  0.36
2001 Petryakov S, Chzhan M, Samouilov A, He G, Kuppusamy P, Zweier JL. A bridged loop-gap S-band surface resonator for topical EPR spectroscopy Journal of Magnetic Resonance. 151: 124-128. PMID 11444946 DOI: 10.1006/jmre.2001.2349  0.36
2001 Mitchell JB, Krishna MC, Kuppusamy P, Cook JA, Russo A. Protection against oxidative stress by nitroxides. Experimental Biology and Medicine (Maywood, N.J.). 226: 620-1. PMID 11444094  0.36
2001 Krishna MC, Devasahayam N, Cook JA, Subramanian S, Kuppusamy P, Mitchell JB. Electron paramagnetic resonance for small animal imaging applications. Ilar Journal / National Research Council, Institute of Laboratory Animal Resources. 42: 209-18. PMID 11406720  0.36
2001 He G, Petryakov S, Samouilov A, Chzhan M, Kuppusamy P, Zweier JL. Development of a resonator with automatic tuning and coupling capability to minimize sample motion noise for in vivo EPR spectroscopy Journal of Magnetic Resonance. 149: 218-227. PMID 11318620 DOI: 10.1006/jmre.2001.2293  0.36
2001 Kuppusamy P, Shankar RA, Roubaud VM, Zweier JL. Whole body detection and imaging of nitric oxide generation in mice following cardiopulmonary arrest: Detection of intrinsic nitrosoheme complexes0 Magnetic Resonance in Medicine. 45: 700-707. PMID 11283999 DOI: 10.1002/mrm.1093  0.36
2001 Krishna MC, Subramanian S, Kuppusamy P, Mitchell JB. Magnetic resonance imaging for in vivo assessment of tissue oxygen concentration. Seminars in Radiation Oncology. 11: 58-69. PMID 11146043  0.36
2001 He G, Samouilov A, Kuppusamy P, Zweier JL. In vivo EPR imaging of the distribution and metabolism of nitroxide radicals in human skin Journal of Magnetic Resonance. 148: 155-164. PMID 11133289 DOI: 10.1006/jmre.2000.2226  0.36
2001 Ilangovan G, Li H, Zweier JL, Kuppusamy P. Electrochemical preparation and EPR studies of lithium phthalocyanine. 3. Measurements of oxygen concentration in tissues and biochemical reactions Journal of Physical Chemistry B. 105: 5323-5330. DOI: 10.1021/jp010130+  0.36
2001 Manivannan A, Yanagi H, Ilangovan G, Kuppusamy P. Lithium naphthalocyanine as a new molecular radical probe for electron paramagnetic resonance oximetry Journal of Magnetism and Magnetic Materials. 233.  0.36
2000 Mitchell JB, Russo A, Kuppusamy P, Krishna MC. Radiation, radicals, and images. Annals of the New York Academy of Sciences. 899: 28-43. PMID 10863527  0.36
2000 Velan SS, Spencer RGS, Zweier JL, Kuppusamy P. Electron paramagnetic resonance oxygen mapping (EPROM): Direct visualization of oxygen concentration in tissue Magnetic Resonance in Medicine. 43: 804-809. PMID 10861874 DOI: 10.1002/1522-2594(200006)43:6<804::AID-MRM5>3.0.CO;2-B  0.36
2000 Shankar RA, Hideg K, Zweier JL, Kuppusamy P. Targeted antioxidant properties of N-[(tetramethyl-3-pyrroline-3- carboxamido)propyl]phthalimide and its nitroxide metabolite in preventing postischemic myocardial injury Journal of Pharmacology and Experimental Therapeutics. 292: 838-845. PMID 10688595  0.36
2000 Ilangovan G, Zweier JL, Kuppusamy P. Electrochemical preparation and epr studies of lithium phthalocyanine. Part 2: Particle-size-dependent line broadening by molecular oxygen and its implications as an oximetry probe Journal of Physical Chemistry B. 104: 9404-9410.  0.36
2000 Ilangovan G, Zweier JL, Kuppusamy P. Electrochemical Preparation and EPR Studies of Lithium Phthalocyanine: Evaluation of the Nucleation and Growth Mechanism and Evidence for Potential-Dependent Phase Formation Journal of Physical Chemistry B. 104: 4047-4059.  0.36
1999 Zweier JL, Samouilov A, Kuppusamy P. Non-enzymatic nitric oxide synthesis in biological systems Biochimica Et Biophysica Acta - Bioenergetics. 1411: 250-262. PMID 10320661 DOI: 10.1016/S0005-2728(99)00018-3  0.36
1999 Chzhan M, Kuppusamy P, Samouilov A, He G, Zweier JL. A Tunable Reentrant Resonator with Transverse Orientation of Electric Field for in Vivo EPR Spectroscopy Journal of Magnetic Resonance. 137: 373-378. PMID 10089171 DOI: 10.1006/jmre.1998.1689  0.36
1998 Ha HC, Sirisoma NS, Kuppusamy P, Zweier JL, Woster PM, Casero RA. The natural polyamine spermine functions directly as a free radical scavenger Proceedings of the National Academy of Sciences of the United States of America. 95: 11140-11145. PMID 9736703 DOI: 10.1073/Pnas.95.19.11140  0.36
1998 Samouilov A, Kuppusamy P, Zweier JL. Evaluation of the magnitude and rate of nitric oxide production from nitrite in biological systems Archives of Biochemistry and Biophysics. 357: 1-7. PMID 9721176 DOI: 10.1006/abbi.1998.0785  0.36
1998 Kuppusamy P, Shankar RA, Zweier JL. In vivo measurement of arterial and venous oxygenation in the rat using 3D spectral-spatial electron paramagnetic resonance imaging Physics in Medicine and Biology. 43: 1837-1844. PMID 9703045 DOI: 10.1088/0031-9155/43/7/003  0.36
1998 Zweier JL, Chzhan M, Samouilov A, Kuppusamy P. Electron paramagnetic resonance imaging of the rat heart Physics in Medicine and Biology. 43: 1823-1835. PMID 9703044 DOI: 10.1088/0031-9155/43/7/002  0.36
1998 Roubaud V, Sankarapandi S, Kuppusamy P, Tordo P, Zweier JL. Quantitative measurement of superoxide generation and oxygen consumption from leukocytes using electron paramagnetic resonance spectroscopy Analytical Biochemistry. 257: 210-217. PMID 9514781 DOI: 10.1006/abio.1997.2542  0.36
1997 Seacat AM, Kuppusamy P, Zweier JL, Yager JD. ESR identification of free radicals formed from the oxidation of catechol estrogens by Cu2+ Archives of Biochemistry and Biophysics. 347: 45-52. PMID 9344463 DOI: 10.1006/abbi.1997.0323  0.36
1997 Roubaud V, Sankarapandi S, Kuppusamy P, Tordo P, Zweier JL. Quantitative measurement of superoxide generation using the spin trap 5- (diethoxyphosphoryl)-5-methyl-1-pyrroline-N-oxide Analytical Biochemistry. 247: 404-411. PMID 9177705 DOI: 10.1006/abio.1997.2067  0.36
1997 Kuppusamy P, Wang P, Chzhan M, Zweier JL. High resolution electron paramagnetic resonance imaging of biological samples with a single line paramagnetic label Magnetic Resonance in Medicine. 37: 479-483. PMID 9094068 DOI: 10.1002/mrm.1910370402  0.36
1997 Vallyathan V, Leonard S, Kuppusamy P, Pack D, Chzhan M, Sanders SP, Zweir JL. Oxidative stress in silicosis: Evidence for the enhanced clearance of free radicals from whole lungs Molecular and Cellular Biochemistry. 168: 125-132. PMID 9062901 DOI: 10.1023/A:1006850920080  0.36
1996 Schauer DA, Desrosiers MF, Kuppusamy P, Zweier JL. Radiation dosimetry of an accidental overexposure using EPR spectrometry and imaging of human bone Applied Radiation and Isotopes. 47: 1345-1350. PMID 9022195 DOI: 10.1016/S0969-8043(96)00203-5  0.36
1996 Primiano T, Kensler TW, Kuppusamy P, Zweier JL, Sutter TR. Induction of hepatic heme oxygenase-1 and ferritin in rats by cancer chemopreventive dithiolethiones Carcinogenesis. 17: 2291-2296. PMID 8968040 DOI: 10.1093/Carcin/17.11.2291  0.36
1996 Kuppusamy P, Wang P, Samouilov A, Zweier JL. Spatial mapping of nitric oxide generation in the ischemic heart using electron paramagnetic resonance imaging Magnetic Resonance in Medicine. 36: 212-218. PMID 8843374  0.36
1996 Serrano CV, Mikhail EA, Wang P, Noble B, Kuppusamy P, ZweierJay JL. Superoxide and hydrogen peroxide induce CD18-mediated adhesion in the postischemic heart Biochimica Et Biophysica Acta - Molecular Basis of Disease. 1316: 191-202. PMID 8781538 DOI: 10.1016/0925-4439(96)00025-7  0.36
1996 Kuppusamy P, Chzhan M, Wang P, Zweier JL. Three-dimensional gated EPR imaging of the beating heart: Time-resolved measurements of free radical distribution during the cardiac contractile cycle Magnetic Resonance in Medicine. 35: 323-328. PMID 8699943  0.36
1996 Kuppusamy P, Zweier JL. A forward-subtraction procedure for removing hyperfine artifacts in electron paramagnetic resonance imaging Magnetic Resonance in Medicine. 35: 316-322. PMID 8699942  0.36
1996 Li Y, Kuppusamy P, Zweier JL, Trush MA. Role of Cu/Zn-superoxide dismutase in xenobiotic activation. II. Biological effects resulting from the Cu/Zn-superoxide dismutase-accelerated oxidation of the benzene metabolite 1,4-hydroquinone Molecular Pharmacology. 49: 412-421. PMID 8643080  0.36
1996 Li Y, Kuppusamy P, Zweier JL, Trush MA. Role of Cu/Zn-superoxide dismutase in xenobiotic activation. I. Chemical reactions involved in the Cu/Zn-superoxide dismutase-accelerated oxidation of the benzene metabolite 1,4-hydroquinone Molecular Pharmacology. 49: 404-411. PMID 8643079  0.36
1996 Kuppusamy P, Ohnishi ST, Numagami Y, Ohnishi T, Zweier JL. Imaging of nitric oxide generation in the rat brain Research On Chemical Intermediates. 22: 605-613. DOI: 10.1163/156856796X00232  0.36
1996 Kuppusamy P, Zweier JL. Hyperfine artifacts in electron paramagnetic resonance imaging Research On Chemical Intermediates. 22: 593-604. DOI: 10.1163/156856796X00223  0.36
1996 Xu KY, Kuppusamy P, Zweier JL, C.becker L. ATP protects against free radical induced inhibition of the cardiac Na+,K+-ATPase Faseb Journal. 10.  0.36
1995 Kuppusamy P, Chzhan M, Zweier JL. Development and Optimization of Three-Dimensional Spatial EPR Imaging for Biological Organs and Tissues Journal of Magnetic Resonance, Series B. 106: 122-130. PMID 7850182 DOI: 10.1006/jmrb.1995.1022  0.36
1995 Li Y, Kuppusamy P, Zweier JL, Trush MA. ESR evidence for the generation of reactive oxygen species from the copper-mediated oxidation of the benzene metabolite, hydroquinone: role in DNA damage Chemico-Biological Interactions. 94: 101-120. PMID 7828218 DOI: 10.1016/0009-2797(94)03326-4  0.36
1995 Zweier JL, Wang P, Kuppusamy P. Direct measurement of nitric oxide generation in the ischemic heart using electron paramagnetic resonance spectroscopy Journal of Biological Chemistry. 270: 304-307. PMID 7814391 DOI: 10.1074/jbc.270.1.304  0.36
1995 Kuppusamy P, Wang P, Zweier JL. Three‐dimensional spatial EPR imaging of the rat heart Magnetic Resonance in Medicine. 34: 99-105. PMID 7674904 DOI: 10.1002/mrm.1910340115  0.36
1995 Chzhan M, Kuppusamy P, Zweier JL. Development of an Electronically Tunable L-Band Resonator for EPR Spectroscopy and Imaging of Biological Samples Journal of Magnetic Resonance, Series B. 108: 67-72. PMID 7627435 DOI: 10.1006/jmrb.1995.1103  0.36
1995 Kuppusamy P, Chzhan M, Samouilov A, Wang PH, Zweier JL. Mapping the Spin-Density and Lineshape Distribution of Free Radicals Using 4D Spectral-Spatial EPR Imaging Journal of Magnetic Resonance, Series B. 107: 116-125. PMID 7599947 DOI: 10.1006/jmrb.1995.1067  0.36
1995 Kuppusamy P, Ohnishi ST, Numagami Y, Ohnishi T, Zweier JL. Three-dimensional imaging of nitric oxide production in the rat brain subjected to ischemia-hypoxia Journal of Cerebral Blood Flow and Metabolism. 15: 899-903. PMID 7593349 DOI: 10.1038/Jcbfm.1995.114  0.36
1995 Zweier JL, Wang P, Samouilov A, Kuppusamy P. Enzyme-independent formation of nitric oxide in biological tissues Nature Medicine. 1: 804-809. PMID 7585184 DOI: 10.1038/nm0895-804  0.36
1995 Meyer DJ. Enzymatic/non-enzymatic formation of nitric oxide. Nature Medicine. 1: 1103-4. PMID 7584968 DOI: 10.1038/nm1195-1103b  0.36
1994 Zweier JL, Kuppusamy P, Thompson-Gorman S, Klunk D, Lutty GA. Measurement and characterization of free radical generation in reoxygenated human endothelial cells American Journal of Physiology - Cell Physiology. 266. PMID 8166233  0.36
1994 Sanders SP, Harrison SJ, Kuppusamy P, Sylvester JT, Zweier JL. A comparative study of EPR spin trapping and cytochrome c reduction techniques for the measurement of superoxide anions Free Radical Biology and Medicine. 16: 753-761. PMID 8070678 DOI: 10.1016/0891-5849(94)90190-2  0.36
1994 Chen K, Ng CE, Zweier JL, Kuppusamy P, Glickson JD, Swartz HM. Measurement of the intracellular concentration of oxygen in a cell perfusion system. Magnetic Resonance in Medicine. 31: 668-72. PMID 8057819 DOI: 10.1002/Mrm.1910310613  0.36
1994 Zweier JL, Broderick R, Kuppusamy P, Thompson-Gorman S, Lutty GA. Determination of the mechanism of free radical generation in human aortic endothelial cells exposed to anoxia and reoxygenation Journal of Biological Chemistry. 269: 24156-24162. PMID 7929072  0.36
1994 Zweier JL, Chzhan M, Ewert U, Schneider G, Kuppusamy P. Development of a Highly Sensitive Probe for Measuring Oxygen in Biological Tissues Journal of Magnetic Resonance, Series B. 105: 52-57. PMID 7921671 DOI: 10.1006/jmrb.1994.1099  0.36
1994 Zweier JL, Kuppusamy P. In vivo EPR spectroscopy of free radicals in the heart Environmental Health Perspectives. 102: 45-51. PMID 7705304  0.36
1993 Shandelya SML, Kuppusamy P, Weisfeldt ML, Zweier JL. Evaluation of the role of polymorphonuclear leukocytes on contractile function in myocardial reperfusion injury: Evidence for plasma-mediated leukocyte activation Circulation. 87: 536-546. PMID 8381059  0.36
1993 Sanders SP, Zweier JL, Kuppusamy P, Harrison SJ, Bessert DJP, Gabrielson EW, Sylvester JT. Hyperoxic sheep pulmonary microvascular endothelial cells generate free radicals via mitochondrial electron transport Journal of Clinical Investigation. 91: 46-52. PMID 8380815 DOI: 10.1172/JCI116198  0.36
1993 Shandelya SML, Kuppusamy P, Herskowitz A, Weisfeldt ML, Zweier JL. Soluble complement receptor type 1 inhibits the complement pathway and prevents contractile failure in the postischemic heart: Evidence that complement activation is required for neutrophil-mediated reperfusion injury Circulation. 88: 2812-2826. PMID 8252695  0.36
1993 Kuppusamy P, Zweier JL. Identification and quantitation of free radicals and paramagnetic centers from complex multi-component EPR spectra Applied Radiation and Isotopes. 44: 367-372. DOI: 10.1016/0969-8043(93)90249-A  0.36
1993 Chzhan M, Shteynbuk M, Kuppusamy P, Zweier JL. An Optimized L-Band Ceramic Resonator for EPR Imaging of Biological Samples Journal of Magnetic Resonance, Series A. 105: 49-53. DOI: 10.1006/jmra.1993.1246  0.36
1992 Gabrielson EW, Kuppusamy P, Povey AC, Zweier JL, Harris CC. Measurement of neutrophil activation and epidermal cell toxicity by palytoxin and 12-o-tetradecanoylphorbol-13-acetate Carcinogenesis. 13: 1671-1674. PMID 1356652 DOI: 10.1093/carcin/13.9.1671  0.36
1992 Grill HP, Zweier JL, Kuppusamy P, Weisfeldt ML, Flaherty JT. Direct measurement of myocardial free radical generation in an in vivo model: Effects of postischemic reperfusion and treatment with human recombinant superoxide dismutase Journal of the American College of Cardiology. 20: 1604-1611. PMID 1333498 DOI: 10.1016/0735-1097(92)90457-X  0.36
1991 Guyton KZ, Bhan P, Kuppusamy P, Zweier JL, Trush MA, Kensler TW. Free radical-derived quinone methide mediates skin tumor promotion by butylated hydroxytoluene hydroperoxide: Expanded role for electrophiles in multistage carcinogenesis Proceedings of the National Academy of Sciences of the United States of America. 88: 946-950. PMID 1846971  0.36
1991 Swauger JE, Dolan PM, Zweier JL, Kuppusamy P, Kensler TW. Role of the benzoyloxyl radical in DNA damage mediated by benzoyl peroxide Chemical Research in Toxicology. 4: 223-228. PMID 1782351  0.36
1991 Zweier JL, Thompson-Gorman S, Kuppusamy P. Measurement of oxygen concentrations in the intact beating heart using electron paramagnetic resonance spectroscopy: A technique for measuring oxygen concentrations in situ Journal of Bioenergetics and Biomembranes. 23: 855-871. PMID 1663949 DOI: 10.1007/BF00786005  0.36
1991 Kukreja RC, Kearns AA, Zweier JL, Kuppusamy P, Hess ML. Singlet oxygen interaction with Ca2+-ATPase of cardiac sarcoplasmic reticulum Circulation Research. 69: 1003-1014. PMID 1657435 DOI: 10.1161/01.Res.69.4.1003  0.36
1991 Zweier JL, Kuppusamy P. Study of free radicals in the intact beating heart using low frequency electron paramagnetic resonance spectroscopy Physica Medica. 7: 29-37.  0.36
1990 Levy A, Kuppusamy P, Rifkind JM. Multiple heme pocket subconformations of methemoglobin associated with distal histidine interactions Biochemistry. 29: 9311-9316. PMID 2174256  0.36
1989 Zweier JL, Duke SS, Kuppusamy P, Sylvester JT, Gabrielson EW. Electron paramagnetic resonance evidence that cellular oxygen toxicity is caused by the generation of superoxide and hydroxyl free radicals Febs Letters. 252: 12-16. PMID 2547649 DOI: 10.1016/0014-5793(89)80881-6  0.36
1989 Kuppusamy P, Zweier JL. Characterization of free radical generation by xanthine oxidase. Evidence for hydroxyl radical generation Journal of Biological Chemistry. 264: 9880-9884. PMID 2542334  0.36
1989 Rajalakshmi A, Radha A, Seshasayee M, Kuppusamy P, Manoharan PT. Crystal and molecular structure of tetraethyl-ammonium bis (stilbene 1,2-dithiolato) nickelate(III) Zeitschrift Fur Kristallographie - New Crystal Structures. 187: 159-164. DOI: 10.1524/zkri.1989.187.1-2.159  0.36
1989 Zweier JL, Kuppusamy P. Electron paramagnetic resonance studies of free radicals in the perfused heart Physica Medica. 5: 289-296.  0.36
1988 Zweier JL, Kuppusamy P. Electron paramagnetic resonance measurements of free radicals in the intact beating heart: A technique for detection and characterization of free radicals in whole biological tissues Proceedings of the National Academy of Sciences of the United States of America. 85: 5703-5707. PMID 2840672  0.36
1988 Zweier JL, Kuppusamy P, Lutty GA. Measurement of endothelial cell free radical generation: Evidence for a central mechanism of free radical injury in postischemic tissues Proceedings of the National Academy of Sciences of the United States of America. 85: 4046-4050. PMID 2836868  0.36
1987 Kuppusamy P, Manoharan PT. Magnetic properties of some exchange coupled [Ni(mnt)2]- dimers Proceedings of the Indian Academy of Sciences - Chemical Sciences. 98: 115-129. DOI: 10.1007/BF02886285  0.36
1985 Kuppusamy P, Manoharan PT. Anisotropic exchange interaction in tetrabutylammonium bis(stilbene-1,2-dithiolato)nickelate(III), [NBu4][Ni(sdt)2] Chemical Physics Letters. 118: 159-163. DOI: 10.1016/0009-2614(85)85289-1  0.36
1985 Kuppusamy P, Venkatalakshmi N, Manoharan PT. Crystal and molecular structure of N-methylphenazinium bis(maleonitriledithiolato)gold(III), [NMP]+[Au(mnt)2]- Journal of Crystallographic and Spectroscopic Research. 15: 629-641. DOI: 10.1007/BF01164776  0.36
1985 Kuppusamy P, Manoharan PT, Mahadevan C, Seshasayee M. Crystal and molecular structure of N-methylphenazinium bis(maleodinitriledithiolato)nickelate(III), [NMP]+ [Ni(mnt)2]- Journal of Crystallographic and Spectroscopic Research. 15: 359-376. DOI: 10.1007/BF01160728  0.36
1985 Mahadevan C, Seshasayee M, Kuppusamy P, Manoharan PT. Crystal and molecular structure of N-methylphenazinium bis(benzene-1,2-dithiolato)nickelate(III). Structure of (C13H11N2)[Ni(S2C6H4)2] Journal of Crystallographic and Spectroscopic Research. 15: 305-316. DOI: 10.1007/BF01160724  0.36
1985 Kuppusamy P, Manoharan PT. Exchange interactions in bis(tetramethylammonium) bis(maleonitriledithiolato)cuprate(II), [NMe4]2[Cu(mnt)2]: A quasi-1-D weak-exchange system Inorganic Chemistry. 24: 3053-3057.  0.36
1984 Kuppusamy P, Ramakrishna BL, Manoharan PT. Exchange interactions in some low-dimensional metal dithiolene complexes Proceedings of the Indian Academy of Sciences - Chemical Sciences. 93: 977-1001. DOI: 10.1007/BF02840341  0.36
1984 Mahadevan C, Seshasayee M, Kuppusamy P, Manoharan PT. Crystal and molecular structure of tetra-n-butylammoniumbis(stilbenedithiolato)-nickelate(III) Journal of Crystallographic and Spectroscopic Research. 14: 179-191. DOI: 10.1007/BF01189559  0.36
1984 Kuppusamy P, Ramakrishna BL, Manoharan PT. EPR, magnetic, and structural investigations on the weak-exchange Heisenberg linear chain bis(N-methylphenazinium) bis(dicyanoethenedithiolato)cuprate(II), [(NMP)2][Cu(mnt)2] Inorganic Chemistry. 23: 3886-3892.  0.36
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