James R. Woodgett - Publications

Medical Biophysics University of Toronto, Toronto, ON, Canada 
Molecular Biology, Cell Biology

296 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Liu Y, Huang Q, Wei Z, Ma S, Woodgett JR, Li M, Li J. GSK-3 mediates nuclear translocation of p62/SQSTM1 in MPTP-induced mouse model of Parkinson's disease. Neuroscience Letters. 136177. PMID 34400288 DOI: 10.1016/j.neulet.2021.136177  1
2021 Bali SK, Bryce D, Prein C, Woodgett JR, Beier F. Glycogen synthase kinase 3 alpha/beta deletion induces precocious growth plate remodeling in mice. Journal of Molecular Medicine (Berlin, Germany). PMID 33609145 DOI: 10.1007/s00109-021-02049-3  1
2020 Sinha S, Dwivedi N, Woodgett J, Tao S, Howard C, Fields TA, Jamadar A, Rao R. Glycogen synthase kinase-3β inhibits tubular regeneration in acute kidney injury by a FoxM1-dependent mechanism. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 32813289 DOI: 10.1096/Fj.202000526Rr  1
2020 Li J, Ma S, Chen J, Hu K, Li Y, Zhang Z, Su Z, Woodgett JR, Li M, Huang Q. GSK-3β Contributes to Parkinsonian Dopaminergic Neuron Death: Evidence From Conditional Knockout Mice and Tideglusib. Frontiers in Molecular Neuroscience. 13: 81. PMID 32581704 DOI: 10.3389/Fnmol.2020.00081  1
2019 Dowling RJO, Kalinsky K, Hayes DF, Bidard FC, Cescon DW, Chandarlapaty S, Deasy JO, Dowsett M, Gray RJ, Henry NL, Meric-Bernstam F, Perlmutter J, Sledge GW, Bratman SV, Carey LA, ... ... Woodgett JR, et al. Toronto Workshop on Late Recurrence in Estrogen Receptor-Positive Breast Cancer: Part 1: Late Recurrence: Current Understanding, Clinical Considerations. Jnci Cancer Spectrum. 3: pkz050. PMID 32337479 DOI: 10.1093/Jncics/Pkz050  1
2019 Dowling RJO, Sparano JA, Goodwin PJ, Bidard FC, Cescon DW, Chandarlapaty S, Deasy JO, Dowsett M, Gray RJ, Henry NL, Meric-Bernstam F, Perlmutter J, Sledge GW, Thorat MA, Bratman SV, ... ... Woodgett JR, et al. Toronto Workshop on Late Recurrence in Estrogen Receptor-Positive Breast Cancer: Part 2: Approaches to Predict and Identify Late Recurrence, Research Directions. Jnci Cancer Spectrum. 3: pkz049. PMID 32337478 DOI: 10.1093/Jncics/Pkz049  1
2019 Woodgett JR. Who Actually Funds Cancer Research? Jnci Cancer Spectrum. 3: pkz070. PMID 32328559 DOI: 10.1093/Jncics/Pkz070  0.01
2019 Wang DY, Jiang Z, Ben-David Y, Woodgett JR, Zacksenhaus E. Molecular stratification within triple-negative breast cancer subtypes. Scientific Reports. 9: 19107. PMID 31836816 DOI: 10.1038/S41598-019-55710-W  1
2019 Hurcombe JA, Lay AC, Ni L, Barrington AF, Woodgett JR, Quaggin SE, Welsh GI, Coward RJ. Podocyte GSK3α is important for autophagy and its loss detrimental for glomerular function. Faseb Bioadvances. 1: 498-510. PMID 31825015 DOI: 10.1096/fba.2019-00011  0.01
2019 Ahmad F, Woodgett JR. Emerging roles of GSK-3α in pathophysiology: Emphasis on cardio-metabolic disorders. Biochimica Et Biophysica Acta. Molecular Cell Research. 118616. PMID 31785335 DOI: 10.1016/J.Bbamcr.2019.118616  1
2019 Kurgan N, Whitley KC, Maddalena LA, Moradi F, Stoikos J, Hamstra SI, Rubie EA, Kumar M, Roy BD, Woodgett JR, Stuart JA, Fajardo VA. A Low-Therapeutic Dose of Lithium Inhibits GSK3 and Enhances Myoblast Fusion in C2C12 Cells. Cells. 8. PMID 31671858 DOI: 10.3390/Cells8111340  1
2019 Ahmad F, Singh AP, Tomar D, Rahmani M, Zhang Q, Woodgett JR, Tilley DG, Lal H, Force T. Cardiomyocyte-GSK-3α promotes mPTP opening and heart failure in mice with chronic pressure overload. Journal of Molecular and Cellular Cardiology. PMID 30928428 DOI: 10.1016/J.Yjmcc.2019.03.020  1
2019 Wang DY, Gendoo DMA, Ben-David Y, Woodgett JR, Zacksenhaus E. A subgroup of microRNAs defines PTEN-deficient, triple-negative breast cancer patients with poorest prognosis and alterations in RB1, MYC, and Wnt signaling. Breast Cancer Research : Bcr. 21: 18. PMID 30704524 DOI: 10.1186/S13058-019-1098-Z  1
2019 Hurcombe JA, Hartley P, Lay AC, Ni L, Bedford JJ, Leader JP, Singh S, Murphy A, Scudamore CL, Marquez E, Barrington AF, Pinto V, Marchetti M, Wong LF, Uney J, ... ... Woodgett JR, et al. Podocyte GSK3 is an evolutionarily conserved critical regulator of kidney function. Nature Communications. 10: 403. PMID 30679422 DOI: 10.1038/S41467-018-08235-1  1
2018 Tao L, Xu M, Dai X, Ni T, Li D, Jin F, Wang H, Tao L, Pan B, Woodgett JR, Qian Y, Liu Y. Polypharmacological Profiles Underlying the Antitumor Property of Root (Danshen) Interfering with NOX-Dependent Neutrophil Extracellular Traps. Oxidative Medicine and Cellular Longevity. 2018: 4908328. PMID 30210653 DOI: 10.1155/2018/4908328  1
2018 Garzia L, Kijima N, Morrissy AS, De Antonellis P, Guerreiro-Stucklin A, Holgado BL, Wu X, Wang X, Parsons M, Zayne K, Manno A, Kuzan-Fischer C, Nor C, Donovan LK, Liu J, ... ... Woodgett JR, et al. A Hematogenous Route for Medulloblastoma Leptomeningeal Metastases. Cell. 173: 1549. PMID 29856958 DOI: 10.1016/J.Cell.2018.05.033  1
2018 Liu JC, Granieri L, Shrestha M, Wang DY, Vorobieva I, Rubie EA, Jones R, Ju Y, Pellecchia G, Jiang Z, Palmerini CA, Ben-David Y, Egan SE, Woodgett JR, Bader GD, et al. Identification of CDC25 as a Common Therapeutic Target for Triple-Negative Breast Cancer. Cell Reports. 23: 112-126. PMID 29617654 DOI: 10.1016/J.Celrep.2018.03.039  1
2018 Garzia L, Kijima N, Morrissy AS, De Antonellis P, Guerreiro-Stucklin A, Holgado BL, Wu X, Wang X, Parsons M, Zayne K, Manno A, Kuzan-Fischer C, Nor C, Donovan LK, Liu J, ... ... Woodgett JR, et al. A Hematogenous Route for Medulloblastoma Leptomeningeal Metastases. Cell. 172: 1050-1062.e14. PMID 29474906 DOI: 10.1016/J.Cell.2018.01.038  1
2018 Bhattacharjee R, Goswami S, Dey S, Gangoda M, Brothag C, Eisa A, Woodgett J, Phiel C, Kline D, Vijayaraghavan S. Isoform specific requirement for GSK3α in sperm for male fertility. Biology of Reproduction. PMID 29385396 DOI: 10.1093/Biolre/Ioy020  0.01
2018 Patterson AR, Endale M, Lampe K, Aksoylar HI, Flagg A, Woodgett JR, Hildeman D, Jordan MB, Singh H, Kucuk Z, Bleesing J, Hoebe K. Gimap5-dependent inactivation of GSK3β is required for CD4+ T cell homeostasis and prevention of immune pathology. Nature Communications. 9: 430. PMID 29382851 DOI: 10.1038/S41467-018-02897-7  0.01
2018 Gorman JL, Adams JR, Jones EM, Egan SE, Woodgett JR. Abstract A29: Generation of a novel transgenic mouse model with regulatable β-catenin expression to examine importance of activated β-catenin signaling to long-term maintenance of mammary tumor growth Cancer Research. 78. DOI: 10.1158/1538-7445.Mousemodels17-A29  1
2017 Wei C, Stock L, Valanejad L, Zalewski ZA, Karns R, Puymirat J, Nelson D, Witte D, Woodgett J, Timchenko NA, Timchenko L. Correction of GSK3β at young age prevents muscle pathology in mice with myotonic dystrophy type 1. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 29203592 DOI: 10.1096/Fj.201700700R  1
2017 Tran CW, Saibil SD, Le Bihan T, Hamilton SR, Lang KS, You H, Lin AE, Garza KM, Elford AR, Tai K, Parsons ME, Wigmore K, Vainberg MG, Penninger JM, Woodgett JR, et al. Glycogen Synthase Kinase-3 Modulates Cbl-b and Constrains T Cell Activation. Journal of Immunology (Baltimore, Md. : 1950). PMID 29109121 DOI: 10.4049/Jimmunol.1600396  1
2017 Tao L, Cao Y, Wei Z, Jia Q, Yu S, Zhong J, Wang A, Woodgett JR, Lu Y. Xanthatin triggers Chk1-mediated DNA damage response and destabilizes Cdc25C via lysosomal degradation in lung cancer cells. Toxicology and Applied Pharmacology. PMID 29074359 DOI: 10.1016/J.Taap.2017.10.015  1
2017 Cormier KW, Woodgett JR. Recent advances in understanding the cellular roles of GSK-3. F1000research. 6. PMID 28299185 DOI: 10.12688/F1000Research.10557.1  0.01
2017 Patel P, Woodgett JR. Glycogen Synthase Kinase 3: A Kinase for All Pathways? Current Topics in Developmental Biology. 123: 277-302. PMID 28236969 DOI: 10.1016/Bs.Ctdb.2016.11.011  0.01
2017 Jellusova J, Cato MH, Apgar JR, Ramezani-Rad P, Leung CR, Chen C, Richardson AD, Conner EM, Benschop RJ, Woodgett JR, Rickert RC. Gsk3 is a metabolic checkpoint regulator in B cells. Nature Immunology. PMID 28114292 DOI: 10.1038/Ni.3664  0.01
2017 Brethour D, Mehrabian M, Williams D, Wang X, Ghodrati F, Ehsani S, Rubie EA, Woodgett JR, Sevalle J, Xi Z, Rogaeva E, Schmitt-Ulms G. A ZIP6-ZIP10 heteromer controls NCAM1 phosphorylation and integration into focal adhesion complexes during epithelial-to-mesenchymal transition. Scientific Reports. 7: 40313. PMID 28098160 DOI: 10.1038/Srep40313  1
2016 Ruel L, Stambolic V, Ali A, Manoukian AS, Woodgett JR. Regulation of the protein kinase activity of ShaggyZeste-white3 by components of the Wingless pathway in Drosophila cells and embryos. The Journal of Biological Chemistry. 291: 23364. PMID 27825099 DOI: 10.1074/jbc.A116.121790  1
2016 Woodgett J, Loughlin DT. Enabling the Next 25 Years of Cell Biology. Trends in Cell Biology. PMID 27693132 DOI: 10.1016/J.Tcb.2016.09.009  0.01
2016 Zhou A, Lin K, Zhang S, Chen Y, Zhang N, Xue J, Wang Z, Aldape KD, Xie K, Woodgett JR, Huang S. Nuclear GSK3β promotes tumorigenesis by phosphorylating KDM1A and inducing its deubiquitylation by USP22. Nature Cell Biology. PMID 27501329 DOI: 10.1038/Ncb3396  1
2016 Tao L, Sheng X, Zhang L, Li W, Wei Z, Zhu P, Zhang F, Wang A, Woodgett JR, Lu Y. Xanthatin anti-tumor cytotoxicity is mediated via glycogen synthase kinase-3β and β-catenin. Biochemical Pharmacology. PMID 27321043 DOI: 10.1016/J.Bcp.2016.06.009  1
2016 Zhou J, Ahmad F, Parikh S, Hoffman NE, Rajan S, Verma VK, Song J, Yuan A, Shanmughapriya S, Guo Y, Gao E, Koch WJ, Woodgett JR, Muniswamy M, Kishore R, et al. Loss of Adult Cardiac Myocyte GSK-3 Leads to Mitotic Catastrophe Resulting in Fatal Dilated Cardiomyopathy. Circulation Research. PMID 26976650 DOI: 10.1161/Circresaha.116.308544  1
2016 Jin J, Tian R, Pasculescu A, Dai AY, Williton K, Taylor L, Savitski MM, Bantscheff M, Woodgett JR, Colwill K, Pawson T. Mutational analysis of GSK3β protein kinase together with kinome-wide binding and stability studies suggest context-dependent recognition of kinases by the chaperone HSP90. Molecular and Cellular Biology. PMID 26755559 DOI: 10.1128/Mcb.01045-15  1
2015 Wright KL, Adams JR, Liu JC, Loch AJ, Wong RG, Jo CE, Beck LA, Santhanam DR, Weiss L, Mei X, Lane TF, Koralov SB, Done SJ, Woodgett JR, Zacksenhaus E, et al. Ras signaling is a key determinant of metastatic dissemination and poor survival of luminal breast cancer patients. Cancer Research. PMID 26400062 DOI: 10.1158/0008-5472.Can-14-2992  1
2015 Khan KA, Dô F, Marineau A, Doyon P, Clément JF, Woodgett JR, Doble BW, Servant MJ. Fine-Tuning of the RIG-I-Like Receptor/Interferon Regulatory Factor 3-Dependent Antiviral Innate Immune Response by the Glycogen Synthase Kinase 3/β-Catenin Pathway. Molecular and Cellular Biology. 35: 3029-43. PMID 26100021 DOI: 10.1128/Mcb.00344-15  1
2015 Tao S, Kakade VR, Woodgett JR, Pandey P, Suderman ED, Rajagopal M, Rao R. Glycogen synthase kinase-3β promotes cyst expansion in polycystic kidney disease. Kidney International. 87: 1164-75. PMID 25629553 DOI: 10.1038/Ki.2014.427  1
2015 Nørregaard R, Tao S, Nilsson L, Woodgett JR, Kakade V, Yu AS, Howard C, Rao R. Glycogen synthase kinase 3α regulates urine concentrating mechanism in mice. American Journal of Physiology. Renal Physiology. 308: F650-60. PMID 25608967 DOI: 10.1152/Ajprenal.00516.2014  1
2015 Dembowy J, Adissu HA, Liu JC, Zacksenhaus E, Woodgett JR. Effect of glycogen synthase kinase-3 inactivation on mouse mammary gland development and oncogenesis. Oncogene. 34: 3514-26. PMID 25195860 DOI: 10.1038/Onc.2014.279  1
2015 Gorman JL, Parsons M, Zacksenhaus E, Egan S, Chang M, Woodgett JR. Abstract P1-07-24: Modeling breast cancer metastasis in the mouse via measurement of circulating tumor cells Cancer Research. 75. DOI: 10.1158/1538-7445.Sabcs14-P1-07-24  1
2015 Gorman JL, Woodgett JR. Global Approaches to Understanding Protein Kinase Functions Kinomics: Approaches and Applications. 1-45. DOI: 10.1002/9783527683031.ch1  1
2014 Ka M, Condorelli G, Woodgett JR, Kim WY. mTOR regulates brain morphogenesis by mediating GSK3 signaling. Development (Cambridge, England). 141: 4076-86. PMID 25273085 DOI: 10.1242/Dev.108282  1
2014 Ahmad F, Lal H, Zhou J, Vagnozzi RJ, Yu JE, Shang X, Woodgett JR, Gao E, Force T. Cardiomyocyte-specific deletion of Gsk3α mitigates post-myocardial infarction remodeling, contractile dysfunction, and heart failure. Journal of the American College of Cardiology. 64: 696-706. PMID 25125302 DOI: 10.1016/J.Jacc.2014.04.068  1
2014 Liz MA, Mar FM, Santos TE, Pimentel HI, Marques AM, Morgado MM, Vieira S, Sousa VF, Pemble H, Wittmann T, Sutherland C, Woodgett JR, Sousa MM. Neuronal deletion of GSK3β increases microtubule speed in the growth cone and enhances axon regeneration via CRMP-2 and independently of MAP1B and CLASP2. Bmc Biology. 12: 47. PMID 24923837 DOI: 10.1186/1741-7007-12-47  1
2014 Lal H, Ahmad F, Zhou J, Yu JE, Vagnozzi RJ, Guo Y, Yu D, Tsai EJ, Woodgett J, Gao E, Force T. Cardiac fibroblast glycogen synthase kinase-3β regulates ventricular remodeling and dysfunction in ischemic heart. Circulation. 130: 419-30. PMID 24899689 DOI: 10.1161/Circulationaha.113.008364  1
2014 Voskas D, Ling LS, Woodgett JR. Signals controlling un-differentiated states in embryonic stem and cancer cells: role of the phosphatidylinositol 3' kinase pathway. Journal of Cellular Physiology. 229: 1312-22. PMID 24604594 DOI: 10.1002/Jcp.24603  1
2014 Woodgett J. How to Become a Control Freak Science Signaling. 7. DOI: 10.1126/Scisignal.2005802  0.01
2013 Holowacz T, Alexson TO, Coles BL, Doble BW, Kelly KF, Woodgett JR, Van Der Kooy D. The responses of neural stem cells to the level of GSK-3 depend on the tissue of origin. Biology Open. 2: 812-21. PMID 23951407 DOI: 10.1242/Bio.20131941  1
2013 Gillespie JR, Bush JR, Bell GI, Aubrey LA, Dupuis H, Ferron M, Kream B, DiMattia G, Patel S, Woodgett JR, Karsenty G, Hess DA, Beier F. GSK-3β function in bone regulates skeletal development, whole-body metabolism, and male life span. Endocrinology. 154: 3702-18. PMID 23904355 DOI: 10.1210/En.2013-1155  1
2013 Woodgett J. There's more to lithium than Nirvana. Nature Reviews Molecular Cell Biology. 14: 466-466. PMID 23839580 DOI: 10.1038/Nrm3628  0.01
2013 Beurel E, Kaidanovich-Beilin O, Yeh WI, Song L, Palomo V, Michalek SM, Woodgett JR, Harrington LE, Eldar-Finkelman H, Martinez A, Jope RS. Regulation of Th1 cells and experimental autoimmune encephalomyelitis by glycogen synthase kinase-3. Journal of Immunology (Baltimore, Md. : 1950). 190: 5000-11. PMID 23606540 DOI: 10.4049/Jimmunol.1203057  1
2013 Kurpios NA, Girgis-Gabardo A, Hallett RM, Rogers S, Gludish DW, Kockeritz L, Woodgett J, Cardiff R, Hassell JA. Single unpurified breast tumor-initiating cells from multiple mouse models efficiently elicit tumors in immune-competent hosts. Plos One. 8: e58151. PMID 23555570 DOI: 10.1371/Journal.Pone.0058151  1
2013 Zhou J, Freeman TA, Ahmad F, Shang X, Mangano E, Gao E, Farber J, Wang Y, Ma XL, Woodgett J, Vagnozzi RJ, Lal H, Force T. GSK-3α is a central regulator of age-related pathologies in mice. The Journal of Clinical Investigation. 123: 1821-32. PMID 23549082 DOI: 10.1172/Jci64398  1
2013 Ling LS, Voskas D, Woodgett JR. Activation of PDK-1 maintains mouse embryonic stem cell self-renewal in a PKB-dependent manner. Oncogene. 32: 5397-408. PMID 23455320 DOI: 10.1038/Onc.2013.44  1
2013 Ly PT, Wu Y, Zou H, Wang R, Zhou W, Kinoshita A, Zhang M, Yang Y, Cai F, Woodgett J, Song W. Inhibition of GSK3β-mediated BACE1 expression reduces Alzheimer-associated phenotypes. The Journal of Clinical Investigation. 123: 224-35. PMID 23202730 DOI: 10.1172/Jci64516  1
2013 Radulescu S, Ridgway RA, Cordero J, Athineos D, Salgueiro P, Poulsom R, Neumann J, Jung A, Patel S, Woodgett J, Barker N, Pritchard DM, Oien K, Sansom OJ. Acute WNT signalling activation perturbs differentiation within the adult stomach and rapidly leads to tumour formation. Oncogene. 32: 2048-57. PMID 22665058 DOI: 10.1038/Onc.2012.224  1
2012 Jones K, Wei C, Iakova P, Bugiardini E, Schneider-Gold C, Meola G, Woodgett J, Killian J, Timchenko NA, Timchenko LT. GSK3β mediates muscle pathology in myotonic dystrophy Journal of Clinical Investigation. 122: 4461-4472. PMID 23160194 DOI: 10.1172/Jci64081  1
2012 Gulen MF, Bulek K, Xiao H, Yu M, Gao J, Sun L, Beurel E, Kaidanovich-Beilin O, Fox PL, DiCorleto PE, Wang JA, Qin J, Wald DN, Woodgett JR, Jope RS, et al. Inactivation of the enzyme GSK3α by the kinase IKKi promotes AKT-mTOR signaling pathway that mediates interleukin-1-induced Th17 cell maintenance. Immunity. 37: 800-12. PMID 23142783 DOI: 10.1016/J.Immuni.2012.08.019  1
2012 Woodgett J. We must be open about our mistakes Nature. 489: 7-7. PMID 22962696 DOI: 10.1038/489007A  0.08
2012 Zhou W, Chen L, Paul J, Yang S, Li F, Sampson K, Woodgett JR, Beaulieu JM, Gamble KL, Li X. The effects of glycogen synthase kinase-3beta in serotonin neurons. Plos One. 7: e43262. PMID 22912839 DOI: 10.1371/Journal.Pone.0043262  1
2012 Howard C, Tao S, Yang HC, Fogo AB, Woodgett JR, Harris RC, Rao R. Specific deletion of glycogen synthase kinase-3β in the renal proximal tubule protects against acute nephrotoxic injury in mice. Kidney International. 82: 1000-9. PMID 22785175 DOI: 10.1038/Ki.2012.239  1
2012 Itoh S, Saito T, Hirata M, Ushita M, Ikeda T, Woodgett JR, Algül H, Schmid RM, Chung UI, Kawaguchi H. GSK-3α and GSK-3β proteins are involved in early stages of chondrocyte differentiation with functional redundancy through RelA protein phosphorylation. The Journal of Biological Chemistry. 287: 29227-36. PMID 22761446 DOI: 10.1074/Jbc.M112.372086  0.01
2012 Woodgett JR. Can a two-faced kinase be exploited for osteosarcoma? Journal of the National Cancer Institute. 104: 722-3. PMID 22534781 DOI: 10.1093/Jnci/Djs223  1
2012 Kaidanovich-Beilin O, Beaulieu JM, Jope RS, Woodgett JR. Neurological functions of the masterswitch protein kinase - gsk-3. Frontiers in Molecular Neuroscience. 5: 48. PMID 22509152 DOI: 10.3389/Fnmol.2012.00048  1
2012 Hicks JW, Wilson AA, Rubie EA, Woodgett JR, Houle S, Vasdev N. Towards the preparation of radiolabeled 1-aryl-3-benzyl ureas: Radiosynthesis of [(11)C-carbonyl] AR-A014418 by [(11)C]CO(2) fixation. Bioorganic & Medicinal Chemistry Letters. 22: 2099-101. PMID 22321216 DOI: 10.1016/J.Bmcl.2011.12.139  1
2012 Lal H, Zhou J, Ahmad F, Zaka R, Vagnozzi RJ, Decaul M, Woodgett J, Gao E, Force T. Glycogen synthase kinase-3α limits ischemic injury, cardiac rupture, post-myocardial infarction remodeling and death. Circulation. 125: 65-75. PMID 22086876 DOI: 10.1161/Circulationaha.111.050666  1
2012 Kaidanovich-Beilin O, Woodgett JR. Glycogen synthase kinase-3 in neurological diseases Neuromethods. 68: 153-188. DOI: 10.1007/978-1-61779-824-5_9  1
2012 Kaidanovich-Beilin O, Beaulieu JM, Jope RS, Woodgett JR. Neurological functions of the masterswitch protein kinase - Gsk-3 Frontiers in Molecular Neuroscience 1
2011 Jaworski T, Dewachter I, Lechat B, Gees M, Kremer A, Demedts D, Borghgraef P, Devijver H, Kügler S, Patel S, Woodgett JR, Van Leuven F. GSK-3α/β kinases and amyloid production in vivo. Nature. 480: E4-5; discussion E6. PMID 22158250 DOI: 10.1038/Nature10615  1
2011 Lee FH, Kaidanovich-Beilin O, Roder JC, Woodgett JR, Wong AH. Genetic inactivation of GSK3α rescues spine deficits in Disc1-L100P mutant mice. Schizophrenia Research. 129: 74-9. PMID 21498050 DOI: 10.1016/J.Schres.2011.03.032  1
2011 Alon LT, Pietrokovski S, Barkan S, Avrahami L, Kaidanovich-Beilin O, Woodgett JR, Barnea A, Eldar-Finkelman H. Selective loss of glycogen synthase kinase-3α in birds reveals distinct roles for GSK-3 isozymes in tau phosphorylation. Febs Letters. 585: 1158-62. PMID 21419127 DOI: 10.1016/J.Febslet.2011.03.025  1
2011 Kaidanovich-Beilin O, Lipina T, Vukobradovic I, Roder J, Woodgett JR. Assessment of social interaction behaviors Journal of Visualized Experiments : Jove. PMID 21403628 DOI: 10.3791/2473  1
2011 Gillespie JR, Ulici V, Dupuis H, Higgs A, Dimattia A, Patel S, Woodgett JR, Beier F. Deletion of glycogen synthase kinase-3β in cartilage results in up-regulation of glycogen synthase kinase-3α protein expression Endocrinology. 152: 1755-1756. PMID 21325041 DOI: 10.1210/En.2010-1412  1
2011 Patel S, Macaulay K, Woodgett JR. Tissue-specific analysis of glycogen synthase kinase-3α (GSK-3α) in glucose metabolism: effect of strain variation. Plos One. 6: e15845. PMID 21253590 DOI: 10.1371/Journal.Pone.0015845  1
2011 Ahmad I, Morton JP, Singh LB, Radulescu SM, Ridgway RA, Patel S, Woodgett J, Winton DJ, Taketo MM, Wu XR, Leung HY, Sansom OJ. β-Catenin activation synergizes with PTEN loss to cause bladder cancer formation. Oncogene. 30: 178-89. PMID 20818428 DOI: 10.1038/Onc.2010.399  1
2011 Lipina TV, Kaidanovich-Beilin O, Patel S, Wang M, Clapcote SJ, Liu F, Woodgett JR, Roder JC. Genetic and pharmacological evidence for schizophrenia-related Disc1 interaction with GSK-3. Synapse (New York, N.Y.). 65: 234-48. PMID 20687111 DOI: 10.1002/Syn.20839  1
2011 Kaidanovich-Beilin O, Woodgett JR. Generation and characterization of drug-inducible forebrain-specific mice mutant for both glycogen synthase kinase-3 alpha and beta genes F1000research. 2. DOI: 10.7490/F1000Research.2035.1  1
2011 Dembowy J, Woodgett J. Abstract LB-93: The role of GSK-3 in mammary gland development and oncogenesis Cancer Research. 71. DOI: 10.1158/1538-7445.Am2011-Lb-93  1
2010 Voskas D, Ling LS, Woodgett JR. Does GSK-3 provide a shortcut for PI3K activation of Wnt signalling? F1000 Biology Reports. 2: 82. PMID 21283602 DOI: 10.3410/B2-82  1
2010 Woodgett J. Basic research: bizarre but essential Nature. 467: 400-400. PMID 20864980 DOI: 10.1038/467400B  0.01
2010 Song B, Lai B, Zheng Z, Zhang Y, Luo J, Wang C, Chen Y, Woodgett JR, Li M. Inhibitory phosphorylation of GSK-3 by CaMKII couples depolarization to neuronal survival. The Journal of Biological Chemistry. 285: 41122-34. PMID 20841359 DOI: 10.1074/Jbc.M110.130351  1
2010 Radulescu S, Ridgway RA, Appleton P, Kroboth K, Patel S, Woodgett J, Taylor S, Nathke IS, Sansom OJ. Defining the role of APC in the mitotic spindle checkpoint in vivo: APC-deficient cells are resistant to Taxol Oncogene. 29: 6418-6427. PMID 20729907 DOI: 10.1038/Onc.2010.373  1
2010 Liang W, Oudit GY, Patel MM, Shah AM, Woodgett JR, Tsushima RG, Ward ME, Backx PH. Role of phosphoinositide 3-kinase {alpha}, protein kinase C, and L-type Ca2+ channels in mediating the complex actions of angiotensin II on mouse cardiac contractility. Hypertension. 56: 422-9. PMID 20696985 DOI: 10.1161/Hypertensionaha.109.149344  1
2010 Zhou J, Lal H, Chen X, Shang X, Song J, Li Y, Kerkela R, Doble BW, MacAulay K, DeCaul M, Koch WJ, Farber J, Woodgett J, Gao E, Force T. GSK-3α directly regulates β-adrenergic signaling and the response of the heart to hemodynamic stress in mice Journal of Clinical Investigation. 120: 2280-2291. PMID 20516643 DOI: 10.1172/Jci41407  1
2010 McNeill H, Woodgett JR. When pathways collide: collaboration and connivance among signalling proteins in development. Nature Reviews. Molecular Cell Biology. 11: 404-13. PMID 20461097 DOI: 10.1038/Nrm2902  1
2010 Woulfe KC, Gao E, Lal H, Harris D, Fan Q, Vagnozzi R, DeCaul M, Shang X, Patel S, Woodgett JR, Force T, Zhou J. Glycogen synthase kinase-3beta regulates post-myocardial infarction remodeling and stress-induced cardiomyocyte proliferation in vivo. Circulation Research. 106: 1635-45. PMID 20360256 DOI: 10.1161/Circresaha.109.211482  1
2009 Kaidanovich-Beilin O, Lipina TV, Takao K, van Eede M, Hattori S, Laliberté C, Khan M, Okamoto K, Chambers JW, Fletcher PJ, MacAulay K, Doble BW, Henkelman M, Miyakawa T, Roder J, ... Woodgett JR, et al. Abnormalities in brain structure and behavior in GSK-3alpha mutant mice. Molecular Brain. 2: 35. PMID 19925672 DOI: 10.1186/1756-6606-2-35  1
2009 Kim WY, Wang X, Wu Y, Doble BW, Patel S, Woodgett JR, Snider WD. GSK-3 is a master regulator of neural progenitor homeostasis. Nature Neuroscience. 12: 1390-7. PMID 19801986 DOI: 10.1038/Nn.2408  1
2009 Dillon RL, Marcotte R, Hennessy BT, Woodgett JR, Mills GB, Muller WJ. Akt1 and akt2 play distinct roles in the initiation and metastatic phases of mammary tumor progression. Cancer Research. 69: 5057-64. PMID 19491266 DOI: 10.1158/0008-5472.Can-08-4287  1
2009 Noh T, Gabet Y, Cogan J, Shi Y, Tank A, Sasaki T, Criswell B, Dixon A, Lee C, Tam J, Kohler T, Segev E, Kockeritz L, Woodgett J, Müller R, et al. Lef1 haploinsufficient mice display a low turnover and low bone mass phenotype in a gender- and age-specific manner. Plos One. 4: e5438. PMID 19412553 DOI: 10.1371/Journal.Pone.0005438  1
2009 Shen F, Li N, Gade P, Kalvakolanu DV, Weibley T, Doble B, Woodgett JR, Wood TD, Gaffen SL. IL-17 receptor signaling inhibits C/EBPbeta by sequential phosphorylation of the regulatory 2 domain. Science Signaling. 2: ra8. PMID 19244213 DOI: 10.1126/scisignal.2000066  1
2009 Doble BW, Woodgett JR. Exploring pluripotency with chemical genetics. Cell Stem Cell. 4: 98-100. PMID 19200796 DOI: 10.1016/J.Stem.2009.01.005  1
2009 Force T, Woodgett JR. Unique and overlapping functions of GSK-3 isoforms in cell differentiation and proliferation and cardiovascular development. The Journal of Biological Chemistry. 284: 9643-7. PMID 19064989 DOI: 10.1074/Jbc.R800077200  1
2009 Stambolic V, Woodgett JR, Fantus IG, Pritchard KI, Goodwin PJ. Utility of metformin in breast cancer treatment, is neoangiogenesis a risk factor? Breast Cancer Research and Treatment. 114: 387-9. PMID 18438706 DOI: 10.1007/S10549-008-0015-4  1
2008 Patel S, Woodgett J. Glycogen Synthase Kinase-3 and Cancer: Good Cop, Bad Cop? Cancer Cell. 14: 351-353. PMID 18977324 DOI: 10.1016/J.Ccr.2008.10.013  1
2008 Kerkela R, Kockeritz L, Macaulay K, Zhou J, Doble BW, Beahm C, Greytak S, Woulfe K, Trivedi CM, Woodgett JR, Epstein JA, Force T, Huggins GS. Deletion of GSK-3beta in mice leads to hypertrophic cardiomyopathy secondary to cardiomyoblast hyperproliferation. The Journal of Clinical Investigation. 118: 3609-18. PMID 18830417 DOI: 10.1172/Jci36245  1
2008 Kapoor M, Liu S, Shi-wen X, Huh K, McCann M, Denton CP, Woodgett JR, Abraham DJ, Leask A. GSK-3beta in mouse fibroblasts controls wound healing and fibrosis through an endothelin-1-dependent mechanism. The Journal of Clinical Investigation. 118: 3279-90. PMID 18802478 DOI: 10.1172/Jci35381  1
2008 MacAulay K, Woodgett JR. Targeting glycogen synthase kinase-3 (GSK-3) in the treatment of Type 2 diabetes. Expert Opinion On Therapeutic Targets. 12: 1265-74. PMID 18781825 DOI: 10.1517/14728222.12.10.1265  1
2008 Woodgett J. Micromanaging ideas risks impeding flow of potential benefits. Nature. 454: 939-939. PMID 18719566 DOI: 10.1038/454939B  0.04
2008 Patel S, Doble BW, MacAulay K, Sinclair EM, Drucker DJ, Woodgett JR. Tissue-specific role of glycogen synthase kinase 3beta in glucose homeostasis and insulin action. Molecular and Cellular Biology. 28: 6314-28. PMID 18694957 DOI: 10.1128/Mcb.00763-08  1
2008 Kawasaki Y, Kugimiya F, Chikuda H, Kamekura S, Ikeda T, Kawamura N, Saito T, Shinoda Y, Higashikawa A, Yano F, Ogasawara T, Ogata N, Hoshi K, Hofmann F, Woodgett JR, et al. Phosphorylation of GSK-3beta by cGMP-dependent protein kinase II promotes hypertrophic differentiation of murine chondrocytes. The Journal of Clinical Investigation. 118: 2506-15. PMID 18551195 DOI: 10.1172/Jci35243  0.01
2008 Ying QL, Wray J, Nichols J, Batlle-Morera L, Doble B, Woodgett J, Cohen P, Smith A. The ground state of embryonic stem cell self-renewal. Nature. 453: 519-23. PMID 18497825 DOI: 10.1038/Nature06968  1
2008 Bersudsky Y, Shaldubina A, Kozlovsky N, Woodgett JR, Agam G, Belmaker RH. Glycogen synthase kinase-3beta heterozygote knockout mice as a model of findings in postmortem schizophrenia brain or as a model of behaviors mimicking lithium action: negative results. Behavioural Pharmacology. 19: 217-24. PMID 18469539 DOI: 10.1097/FBP.0b013e3282feb099  1
2008 Liu S, Fang X, Hall H, Yu S, Smith D, Lu Z, Fang D, Liu J, Stephens LC, Woodgett JR, Mills GB. Homozygous deletion of glycogen synthase kinase 3beta bypasses senescence allowing Ras transformation of primary murine fibroblasts. Proceedings of the National Academy of Sciences of the United States of America. 105: 5248-53. PMID 18367674 DOI: 10.1073/Pnas.0704242105  1
2008 Vasdev N, LaRonde FJ, Woodgett JR, Garcia A, Rubie EA, Meyer JH, Houle S, Wilson AA. Rationally designed PKA inhibitors for positron emission tomography: Synthesis and cerebral biodistribution of N-(2-(4-bromocinnamylamino)ethyl)-N-[11C]methyl-isoquinoline-5-sulfonamide. Bioorganic & Medicinal Chemistry. 16: 5277-84. PMID 18346896 DOI: 10.1016/J.Bmc.2008.03.013  1
2008 Tanabe K, Liu Z, Patel S, Doble BW, Li L, Cras-Méneur C, Martinez SC, Welling CM, White MF, Bernal-Mizrachi E, Woodgett JR, Permutt MA. Genetic deficiency of glycogen synthase kinase-3beta corrects diabetes in mouse models of insulin resistance. Plos Biology. 6: e37. PMID 18288891 DOI: 10.1371/Journal.Pbio.0060037  1
2008 Salahshor S, Naidoo R, Serra S, Shih W, Tsao MS, Chetty R, Woodgett JR. Frequent accumulation of nuclear E-cadherin and alterations in the Wnt signaling pathway in esophageal squamous cell carcinomas. Modern Pathology : An Official Journal of the United States and Canadian Academy of Pathology, Inc. 21: 271-81. PMID 18084253 DOI: 10.1038/Modpathol.3800990  1
2008 Zeng X, Huang H, Tamai K, Zhang X, Harada Y, Yokota C, Almeida K, Wang J, Doble B, Woodgett J, Wynshaw-Boris A, Hsieh JC, He X. Initiation of Wnt signaling: control of Wnt coreceptor Lrp6 phosphorylation/activation via frizzled, dishevelled and axin functions. Development (Cambridge, England). 135: 367-75. PMID 18077588 DOI: 10.1242/Dev.013540  1
2008 Kapoor M, Liu S, Shi-wen X, Huh K, McCann M, Denton CP, Woodgett JR, Abraham DJ, Leask A. GSK-3β in mouse fibroblasts controls wound healing and fibrosis through an endothelin-1-dependent mechanism (Journal of Clinical Investigation (2008) 118, (3279-3290) DOI: 10.1172/JCI35381) Journal of Clinical Investigation. 118: 3812. DOI: 10.1172/JCI35381R1  1
2008 Scheid MP, Woodgett JR. Cell Survival Signaling through Phosphoinositide 3-kinase and Protein Kinase B Apoptosis and Cancer Therapy: From Cutting-Edge Science to Novel Therapeutic Concepts. 1: 462-489. DOI: 10.1002/9783527619665.ch17  1
2007 MacAulay K, Doble BW, Patel S, Hansotia T, Sinclair EM, Drucker DJ, Nagy A, Woodgett JR. Glycogen synthase kinase 3alpha-specific regulation of murine hepatic glycogen metabolism. Cell Metabolism. 6: 329-37. PMID 17908561 DOI: 10.1016/J.Cmet.2007.08.013  1
2007 Woodgett J. Q&A: Jim Woodgett. Current Biology. 17. PMID 17879460 DOI: 10.1016/J.Cub.2007.05.014  0.04
2007 Kugimiya F, Kawaguchi H, Ohba S, Kawamura N, Hirata M, Chikuda H, Azuma Y, Woodgett JR, Nakamura K, Chung UI. GSK-3beta controls osteogenesis through regulating Runx2 activity. Plos One. 2: e837. PMID 17786208 DOI: 10.1371/Journal.Pone.0000837  0.01
2007 Mishra R, Barthwal MK, Sondarva G, Rana B, Wong L, Chatterjee M, Woodgett JR, Rana A. Glycogen synthase kinase-3beta induces neuronal cell death via direct phosphorylation of mixed lineage kinase 3. The Journal of Biological Chemistry. 282: 30393-405. PMID 17711861 DOI: 10.1074/Jbc.M705895200  1
2007 Doble BW, Woodgett JR. Role of glycogen synthase kinase-3 in cell fate and epithelial-mesenchymal transitions. Cells, Tissues, Organs. 185: 73-84. PMID 17587811 DOI: 10.1159/000101306  1
2007 Linding R, Jensen LJ, Ostheimer GJ, van Vugt MA, Jørgensen C, Miron IM, Diella F, Colwill K, Taylor L, Elder K, Metalnikov P, Nguyen V, Pasculescu A, Jin J, Park JG, ... ... Woodgett JR, et al. Systematic discovery of in vivo phosphorylation networks. Cell. 129: 1415-26. PMID 17570479 DOI: 10.1016/J.Cell.2007.05.052  1
2007 Doble BW, Patel S, Wood GA, Kockeritz LK, Woodgett JR. Functional redundancy of GSK-3alpha and GSK-3beta in Wnt/beta-catenin signaling shown by using an allelic series of embryonic stem cell lines. Developmental Cell. 12: 957-71. PMID 17543867 DOI: 10.1016/J.Devcel.2007.04.001  1
2007 Wei Q, Yokota C, Semenov MV, Doble B, Woodgett J, He X. R-spondin1 is a high affinity ligand for LRP6 and induces LRP6 phosphorylation and beta-catenin signaling. The Journal of Biological Chemistry. 282: 15903-11. PMID 17400545 DOI: 10.1074/Jbc.M701927200  1
2007 Saibil SD, Jones RG, Deenick EK, Liadis N, Elford AR, Vainberg MG, Baerg H, Woodgett JA, Gerondakis S, Ohashi PS. CD4+ and CD8+ T cell survival is regulated differentially by protein kinase Cθ c-Rel, and protein kinase B Journal of Immunology. 178: 2932-2939. PMID 17312138 DOI: 10.4049/Jimmunol.178.5.2932  1
2007 Kaladchibachi SA, Doble B, Anthopoulos N, Woodgett JR, Manoukian AS. Glycogen synthase kinase 3, circadian rhythms, and bipolar disorder: a molecular link in the therapeutic action of lithium. Journal of Circadian Rhythms. 5: 3. PMID 17295926 DOI: 10.1186/1740-3391-5-3  1
2006 Kim WY, Zhou FQ, Zhou J, Yokota Y, Wang YM, Yoshimura T, Kaibuchi K, Woodgett JR, Anton ES, Snider WD. Essential roles for GSK-3s and GSK-3-primed substrates in neurotrophin-induced and hippocampal axon growth. Neuron. 52: 981-96. PMID 17178402 DOI: 10.1016/J.Neuron.2006.10.031  1
2006 Kockeritz L, Doble B, Patel S, Woodgett JR. Glycogen synthase kinase-3--an overview of an over-achieving protein kinase. Current Drug Targets. 7: 1377-88. PMID 17100578 DOI: 10.2174/1389450110607011377  1
2006 Stambolic V, Woodgett JR. Functional distinctions of protein kinase B/Akt isoforms defined by their influence on cell migration. Trends in Cell Biology. 16: 461-6. PMID 16870447 DOI: 10.1016/J.Tcb.2006.07.001  1
2006 Tessier M, Woodgett JR. Role of the Phox homology domain and phosphorylation in activation of serum and glucocorticoid-regulated kinase-3. The Journal of Biological Chemistry. 281: 23978-89. PMID 16790420 DOI: 10.1074/Jbc.M604333200  1
2006 Hu X, Paik PK, Chen J, Yarilina A, Kockeritz L, Lu TT, Woodgett JR, Ivashkiv LB. IFN-gamma suppresses IL-10 production and synergizes with TLR2 by regulating GSK3 and CREB/AP-1 proteins. Immunity. 24: 563-74. PMID 16713974 DOI: 10.1016/J.Immuni.2006.02.014  1
2006 Tessier M, Woodgett JR. Serum and glucocorticoid-regulated protein kinases: variations on a theme. Journal of Cellular Biochemistry. 98: 1391-407. PMID 16619268 DOI: 10.1002/Jcb.20894  1
2006 Chetty R, Serra S, Salahshor S, Alsaad K, Shih W, Blaszyk H, Woodgett JR, Tsao MS. Expression of Wnt-signaling pathway proteins in intraductal papillary mucinous neoplasms of the pancreas: a tissue microarray analysis. Human Pathology. 37: 212-7. PMID 16426922 DOI: 10.1016/J.Humpath.2005.11.002  1
2006 Batt J, Bain J, Goncalves J, Michalski B, Plant P, Fahnestock M, Woodgett J. Differential gene expression profiling of short and long term denervated muscle. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 20: 115-7. PMID 16291642 DOI: 10.1096/Fj.04-3640Fje  1
2006 Morel M, Leroy K, Doble B, Cruz J, Tsai L, Woodgett J, Brion J. P3-307: Glycogen synthase kinase-3beta and the p25 activator of cyclin-dependent kinase-5 decrease neuritogenesis and fast axoplasmic transport in differentiated PC12 cells Alzheimers & Dementia. 2. DOI: 10.1016/J.Jalz.2006.05.1577  1
2006 Woodgett JR. Glycogen Synthase Kinase 3: An Introductory Synopsis Glycogen Synthase Kinase 3 (Gsk-3) and Its Inhibitors: Drug Discovery and Development. 1-23. DOI: 10.1002/9780470052174.ch1  1
2005 Jones RG, Saibil SD, Pun JM, Elford AR, Bonnard M, Pellegrini M, Arya S, Parsons ME, Krawczyk CM, Gerondakis S, Yeh WC, Woodgett JM, Boothby MR, Ohashi PS. NF-κB couples protein kinase B/Akt signaling to distinct survival pathways and the regulation of lymphocyte homeostasis in vivo Journal of Immunology. 175: 3790-3799. PMID 16148125  1
2005 Ohashi PS, Woodgett JR. Modulating autoimmunity: pick your PI3 kinase. Nature Medicine. 11: 924-5. PMID 16145571 DOI: 10.1038/Nm0905-924  1
2005 Woodgett JR, Ohashi PS. GSK3: an in-Toll-erant protein kinase? Nature Immunology. 6: 751-2. PMID 16034428 DOI: 10.1038/Ni0805-751  1
2005 Jin J, Woodgett JR. Chronic activation of protein kinase Bbeta/Akt2 leads to multinucleation and cell fusion in human epithelial kidney cells: events associated with tumorigenesis. Oncogene. 24: 5459-70. PMID 16007218 DOI: 10.1038/Sj.Onc.1208704  1
2005 Salahshor S, Goncalves J, Chetty R, Gallinger S, Woodgett JR. Differential gene expression profile reveals deregulation of pregnancy specific beta1 glycoprotein 9 early during colorectal carcinogenesis. Bmc Cancer. 5: 66. PMID 15982419 DOI: 10.1186/1471-2407-5-66  1
2005 Tyers M, Brown E, Andrews DW, Bergeron JJ, Boone C, Bremner R, Bussey HA, Cross JC, Davies JE, Desjardins M, Dick JE, Dumont DJ, Durocher D, Ellison MJ, Golding GB, ... ... Woodgett JR, et al. Problems with co-funding in Canada. Science (New York, N.Y.). 308: 1867. PMID 15976286 DOI: 10.1126/Science.308.5730.1867B  1
2005 Heisler LE, Torti D, Boutros PC, Watson J, Chan C, Winegarden N, Takahashi M, Yau P, Huang THM, Farnham PJ, Jurisica I, Woodgett JR, Bremner R, Penn LZ, Der SD. CpG Island microarray probe sequences derived from a physical library are representative of CpG Islands annotated on the human genome Nucleic Acids Research. 33: 2952-2961. PMID 15911630 DOI: 10.1093/Nar/Gki582  1
2005 Coles JG, Boscarino C, Takahashi M, Grant D, Chang A, Ritter J, Dai X, Du C, Musso G, Yamabi H, Goncalves J, Kumar AS, Woodgett J, Lu H, Hannigan G. Cardioprotective stress response in the human fetal heart. The Journal of Thoracic and Cardiovascular Surgery. 129: 1128-36. PMID 15867790 DOI: 10.1016/J.Jtcvs.2004.11.055  1
2005 Woodgett JR. Recent advances in the protein kinase B signaling pathway. Current Opinion in Cell Biology. 17: 150-7. PMID 15780591 DOI: 10.1016/J.Ceb.2005.02.010  1
2005 Scheid MP, Parsons M, Woodgett JR. Phosphoinositide-dependent phosphorylation of PDK1 regulates nuclear translocation. Molecular and Cellular Biology. 25: 2347-63. PMID 15743829 DOI: 10.1128/Mcb.25.6.2347-2363.2005  1
2005 Salahshor S, Woodgett JR. The links between axin and carcinogenesis Journal of Clinical Pathology. 58: 225-236. PMID 15735151 DOI: 10.1136/Jcp.2003.009506  1
2004 Patel S, Doble B, Woodgett JR. Glycogen synthase kinase-3 in insulin and Wnt signalling: A double-edged sword? Biochemical Society Transactions. 32: 803-808. PMID 15494020 DOI: 10.1042/Bst0320803  1
2004 Liu S, Yu S, Hasegawa Y, Lapushin R, Xu HJ, Woodgett JR, Mills GB, Fang X. Glycogen synthase kinase 3beta is a negative regulator of growth factor-induced activation of the c-Jun N-terminal kinase. The Journal of Biological Chemistry. 279: 51075-81. PMID 15466414 DOI: 10.1074/Jbc.M408607200  1
2004 Jin J, Smith FD, Stark C, Wells CD, Fawcett JP, Kulkarni S, Metalnikov P, O'Donnell P, Taylor P, Taylor L, Zougman A, Woodgett JR, Langeberg LK, Scott JD, Pawson T. Proteomic, functional, and domain-based analysis of in vivo 14-3-3 binding proteins involved in cytoskeletal regulation and cellular organization. Current Biology : Cb. 14: 1436-50. PMID 15324660 DOI: 10.1016/J.Cub.2004.07.051  1
2004 O'Brien WT, Harper AD, Jové F, Woodgett JR, Maretto S, Piccolo S, Klein PS. Glycogen synthase kinase-3beta haploinsufficiency mimics the behavioral and molecular effects of lithium. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 6791-8. PMID 15282284 DOI: 10.1523/Jneurosci.4753-03.2004  1
2004 Hutchinson JN, Jin J, Cardiff RD, Woodgett JR, Muller WJ. Activation of Akt-1 (PKB-α) Can Accelerate ErbB-2-Mediated Mammary Tumorigenesis but Suppresses Tumor Invasion Cancer Research. 64: 3171-3178. PMID 15126356 DOI: 10.1158/0008-5472.Can-03-3465  1
2004 Beaulieu JM, Sotnikova TD, Yao WD, Kockeritz L, Woodgett JR, Gainetdinov RR, Caron MG. Lithium antagonizes dopamine-dependent behaviors mediated by an AKT/glycogen synthase kinase 3 signaling cascade. Proceedings of the National Academy of Sciences of the United States of America. 101: 5099-104. PMID 15044694 DOI: 10.1073/Pnas.0307921101  1
2004 Ma N, Szmitko P, Brade A, Chu I, Lo A, Woodgett J, Klamut H, Liu FF. Kinase-dead PKB gene therapy combined with hyperthermia for human breast cancer. Cancer Gene Therapy. 11: 52-60. PMID 14681726 DOI: 10.1038/Sj.Cgt.7700655  1
2003 Woodgett JR. Physiological roles of glycogen synthase kinase-3: potential as a therapeutic target for diabetes and other disorders Current Drug Targets. Immune, Endocrine and Metabolic Disorders. 3: 281-290. PMID 14683459 DOI: 10.2174/1568008033340153  1
2003 Scheid MP, Woodgett JR. Unravelling the activation mechanisms of protein kinase B/Akt. Febs Letters. 546: 108-12. PMID 12829245 DOI: 10.1016/S0014-5793(03)00562-3  1
2003 De Strooper B, Woodgett J. Alzheimer's disease: Mental plaque removal. Nature. 423: 392-3. PMID 12761533 DOI: 10.1038/423392A  1
2003 Preston TJ, Woodgett JR, Singh G. JNK1 activity lowers the cellular production of H2O2 and modulates the growth arrest response to scavenging of H2O2 by catalase. Experimental Cell Research. 285: 146-58. PMID 12681294 DOI: 10.1016/S0014-4827(03)00015-6  1
2003 Doble BW, Woodgett JR. GSK-3: tricks of the trade for a multi-tasking kinase. Journal of Cell Science. 116: 1175-86. PMID 12615961 DOI: 10.1242/Jcs.00384  1
2003 Barthwal MK, Sathyanarayana P, Kundu CN, Rana B, Pradeep A, Sharma C, Woodgett JR, Rana A. Negative regulation of mixed lineage kinase 3 by protein kinase B/AKT leads to cell survival. The Journal of Biological Chemistry. 278: 3897-902. PMID 12458207 DOI: 10.1074/Jbc.M211598200  1
2003 Wen HC, Huang WC, Ali A, Woodgett JR, Lin WW. Negative regulation of phosphatidylinositol 3-kinase and Akt signalling pathway by PKC. Cellular Signalling. 15: 37-45. PMID 12401518 DOI: 10.1016/S0898-6568(02)00047-5  1
2003 Woodgett JR. MAP Kinases Handbook of Cell Signaling. 1: 493-497. DOI: 10.1016/B978-012124546-7/50444-7  1
2002 Woodgett JR. Open heart surgery of PI-3 kinase signaling. Cell Cycle (Georgetown, Tex.). 1: 404-5. PMID 12548014 DOI: 10.4161/Cc.1.6.265  1
2002 Claudio JO, Masih-Khan E, Tang H, Gonçalves J, Voralia M, Li ZH, Nadeem V, Cukerman E, Francisco-Pabalan O, Liew CC, Woodgett JR, Stewart AK. A molecular compendium of genes expressed in multiple myeloma. Blood. 100: 2175-86. PMID 12200383 DOI: 10.1182/Blood-2002-01-0008  0.01
2002 Scheid MP, Marignani PA, Woodgett JR. Multiple phosphoinositide 3-kinase-dependent steps in activation of protein kinase B. Molecular and Cellular Biology. 22: 6247-60. PMID 12167717 DOI: 10.1128/Mcb.22.17.6247-6260.2002  1
2002 Jones RG, Elford AR, Parsons MJ, Wu L, Krawczyk CM, Yeh WC, Hakem R, Rottapel R, Woodgett JR, Ohashi PS. CD28-dependent activation of protein kinase B/Akt blocks Fas-mediated apoptosis by preventing death-inducing signaling complex assembly. The Journal of Experimental Medicine. 196: 335-48. PMID 12163562 DOI: 10.1084/Jem.20020307  1
2002 Fang X, Yu S, Tanyi JL, Lu Y, Woodgett JR, Mills GB. Convergence of multiple signaling cascades at glycogen synthase kinase 3: Edg receptor-mediated phosphorylation and inactivation by lysophosphatidic acid through a protein kinase C-dependent intracellular pathway. Molecular and Cellular Biology. 22: 2099-110. PMID 11884598 DOI: 10.1128/Mcb.22.7.2099-2110.2002  1
2002 Manoukian AS, Woodgett JR. Role of glycogen synthase kinase-3 in cancer: regulation by Wnts and other signaling pathways. Advances in Cancer Research. 84: 203-29. PMID 11883528 DOI: 10.1016/S0065-230X(02)84007-6  1
2002 Leroy K, Boutajangout A, Authelet M, Woodgett JR, Anderton BH, Brion JP. The active form of glycogen synthase kinase-3beta is associated with granulovacuolar degeneration in neurons in Alzheimer's disease. Acta Neuropathologica. 103: 91-9. PMID 11810173 DOI: 10.1007/S004010100435  1
2002 Cheng HY, Pitcher GM, Laviolette SR, Whishaw IQ, Tong KI, Kockeritz LK, Wada T, Joza NA, Crackower M, Goncalves J, Sarosi I, Woodgett JR, Oliveira-dos-Santos AJ, Ikura M, van der Kooy D, et al. DREAM is a critical transcriptional repressor for pain modulation. Cell. 108: 31-43. PMID 11792319 DOI: 10.1016/S0092-8674(01)00629-8  1
2001 Ali A, Hoeflich KP, Woodgett JR. Glycogen synthase kinase-3: properties, functions, and regulation. Chemical Reviews. 101: 2527-40. PMID 11749387 DOI: 10.1021/Cr000110O  1
2001 Jin J, Anthopoulos N, Wetsch B, Binari RC, Isaac DD, Andrew DJ, Woodgett JR, Manoukian AS. Regulation of Drosophila tracheal system development by protein kinase B. Developmental Cell. 1: 817-27. PMID 11740943 DOI: 10.1016/S1534-5807(01)00090-9  1
2001 Scheid MP, Woodgett JR. PKB/AKT: Functional insights from genetic models Nature Reviews Molecular Cell Biology. 2: 760-768. PMID 11584303 DOI: 10.1038/35096067  1
2001 Woodgett JR. Judging a protein by more than its name: GSK-3 Science's Stke : Signal Transduction Knowledge Environment. 2001. PMID 11579232 DOI: 10.1126/Stke.2001.100.Re12  1
2001 Scheid MP, Woodgett JR. Phosphatidylinositol 3′ Kinase Signaling in Mammary Tumorigenesis Journal of Mammary Gland Biology and Neoplasia. 6: 83-99. PMID 11467455 DOI: 10.1023/A:1009520616247  1
2001 Ma N, Jin J, Lu F, Woodgett J, Liu FF. The role of protein kinase B (PKB) in modulating heat sensitivity in a human breast cancer cell line International Journal of Radiation Oncology Biology Physics. 50: 1041-1050. PMID 11429232 DOI: 10.1016/S0360-3016(01)01596-6  1
2001 Parsons MJ, Jones RG, Tsao MS, Odermatt B, Ohashi PS, Woodgett JR. Expression of active protein kinase B in T cells perturbs both T and B cell homeostasis and promotes inflammation. Journal of Immunology (Baltimore, Md. : 1950). 167: 42-8. PMID 11418630 DOI: 10.4049/Jimmunol.167.1.42  1
2001 Yarwood SJ, Woodgett JR. Extracellular matrix composition determines the transcriptional response to epidermal growth factor receptor activation Proceedings of the National Academy of Sciences of the United States of America. 98: 4472-4477. PMID 11287658 DOI: 10.1073/Pnas.081069098  1
2001 Hutchinson J, Jin J, Cardiff RD, Woodgett JR, Muller WJ. Activation of Akt (protein kinase B) in mammary epithelium provides a critical cell survival signal required for tumor progression Molecular and Cellular Biology. 21: 2203-2212. PMID 11238953 DOI: 10.1128/Mcb.21.6.2203-2212.2001  1
2001 Ogimoto M, Arimura Y, Katagiri T, Mitomo K, Woodgett JR, Nebreda AR, Mizuno K, Yakura H. Opposing regulation of B cell receptor-induced activation of mitogen-activated protein kinases by CD45 Febs Letters. 490: 97-101. PMID 11172819 DOI: 10.1016/S0014-5793(00)02416-9  1
2001 Diao J, Khine AA, Sarangi F, Hsu E, Iorio C, Tibbles LA, Woodgett JR, Penninger J, Richardson CD. X Protein of Hepatitis B Virus Inhibits Fas-mediated Apoptosis and is Associated with Up-regulation of the SAPK/JNK Pathway Journal of Biological Chemistry. 276: 8328-8340. PMID 11099494 DOI: 10.1074/Jbc.M006026200  1
2001 Hoeflich KP, Woodgett JR. Chapter 13 Mitogen-activated protein kinases and stress Cell and Molecular Response to Stress. 2: 175-193. DOI: 10.1016/S1568-1254(01)80015-2  1
2000 Fang X, Yu SX, Lu Y, Bast RC, Woodgett JR, Mills GB. Phosphorylation and inactivation of glycogen synthase kinase 3 by protein kinase A. Proceedings of the National Academy of Sciences of the United States of America. 97: 11960-5. PMID 11035810 DOI: 10.1073/Pnas.220413597  1
2000 Scanga SE, Ruel L, Binari RC, Snow B, Stambolic V, Bouchard D, Peters M, Calvieri B, Mak TW, Woodgett JR, Manoukian AS. The conserved PI3'K/PTEN/Akt signaling pathway regulates both cell size and survival in Drosophila. Oncogene. 19: 3971-7. PMID 10962553 DOI: 10.1038/Sj.Onc.1203739  1
2000 Lee HY, Suh YA, Robinson MJ, Clifford JL, Hong WK, Woodgett JR, Cobb MH, Mangelsdorf DJ, Kurie JM. Stress pathway activation induces phosphorylation of retinoid X receptor. The Journal of Biological Chemistry. 275: 32193-9. PMID 10938283 DOI: 10.1074/Jbc.M005490200  0.01
2000 Hoeflich KP, Luo J, Rubie EA, Tsao MS, Jin O, Woodgett JR. Requirement for glycogen synthase kinase-3beta in cell survival and NF-kappaB activation. Nature. 406: 86-90. PMID 10894547 DOI: 10.1038/35017574  1
2000 Ohteki T, Parsons M, Zakarian A, Jones RG, Nguyen LT, Woodgett JR, Ohashi PS. Negative regulation of T cell proliferation and interleukin 2 production by the serine threonine kinase GSK-3. The Journal of Experimental Medicine. 192: 99-104. PMID 10880530 DOI: 10.1084/Jem.192.1.99  1
2000 Xavier IJ, Mercier PA, McLoughlin CM, Ali A, Woodgett JR, Ovsenek N. Glycogen synthase kinase 3β negatively regulates both DNA-binding and transcriptional activities of heat shock factor 1 Journal of Biological Chemistry. 275: 29147-29152. PMID 10856293 DOI: 10.1074/Jbc.M002169200  1
2000 Jones RG, Parsons M, Bonnard M, Chan VS, Yeh WC, Woodgett JR, Ohashi PS. Protein kinase B regulates T lymphocyte survival, nuclear factor kappaB activation, and Bcl-X(L) levels in vivo. The Journal of Experimental Medicine. 191: 1721-34. PMID 10811865 DOI: 10.1084/Jem.191.10.1721  1
2000 Scheid MP, Woodgett JR. Protein kinases: Six degrees of separation? Current Biology. 10. PMID 10712899 DOI: 10.1016/S0960-9822(00)00349-3  1
1999 Stambolic V, Mak TW, Woodgett JR. Modulation of cellular apoptotic potential: Contributions to oncogenesis Oncogene. 18: 6094-6103. PMID 10557100 DOI: 10.1038/Sj.Onc.1203126  1
1999 Hoeflich KP, Yeh WC, Yao Z, Mak TW, Woodgett JR. Mediation of TNF receptor-associated factor effector functions by apoptosis signal-regulating kinase-1 (ASK1). Oncogene. 18: 5814-20. PMID 10523862 DOI: 10.1038/Sj.Onc.1202975  1
1999 Tibbles LA, Woodgett JR. The stress-activated protein kinase pathways Cellular and Molecular Life Sciences. 55: 1230-1254. PMID 10487205 DOI: 10.1007/S000180050369  1
1999 Cannons JL, Hoeflich KP, Woodgett JR, Watts TH. Role of the stress kinase pathway in signaling via the T cell costimulatory receptor 4-1BB. Journal of Immunology (Baltimore, Md. : 1950). 163: 2990-8. PMID 10477561  1
1999 Ruel L, Stambolic V, Ali A, Manoukian AS, Woodgett JR. Regulation of the protein kinase activity of Shaggy(zeste-white3) by components of the Wingless pathway in Drosophila cells and embryos Journal of Biological Chemistry. 274: 21790-21796. PMID 10419494 DOI: 10.1074/Jbc.274.31.21790  1
1999 Al-Murrani SW, Woodgett JR, Damuni Z. Expression of I2PP2A, an inhibitor of protein phosphatase 2A, induces c-Jun and AP-1 activity The Biochemical Journal. 341. PMID 10393085 DOI: 10.1042/Bj3410293  1
1999 Lee ST, Hoeflich KP, Wasfy GW, Woodgett JR, Leber B, Andrews DW, Hedley DW, Penn LZ. Bcl-2 targeted to the endoplasmic reticulum can inhibit apoptosis induced by Myc but not etoposide in Rat-1 fibroblasts. Oncogene. 18: 3520-8. PMID 10376530 DOI: 10.1038/Sj.Onc.1202716  1
1999 Wang Q, Somwar R, Bilan PJ, Liu Z, Jin J, Woodgett JR, Klip A. Protein kinase B/Akt participates in GLUT4 translocation by insulin in L6 myoblasts. Molecular and Cellular Biology. 19: 4008-18. PMID 10330141 DOI: 10.1128/Mcb.19.6.4008  1
1999 Nishimura M, Yu G, Levesque G, Zhang DM, Ruel L, Chen F, Milman P, Holmes E, Liang Y, Kawarai T, Jo E, Supala A, Rogaeva E, Xu DM, Janus C, ... ... Woodgett J, et al. Presenilin mutations associated with Alzheimer disease cause defective intracellular trafficking of beta-catenin, a component of the presenilin protein complex. Nature Medicine. 5: 164-9. PMID 9930863 DOI: 10.1038/5526  1
1999 Plyte SE, O'Donovan E, Woodgett JR, Harwood AJ. Glycogen synthase kinase-3 (GSK-3) is regulated during Dictyostelium development via the serpentine receptor cAR3 Development. 126: 325-333. PMID 9847246  1
1999 Al-Murrani SWK, Woodgett JR, Damuni Z. Expression of I2(PP2A), inhibitor of protein phosphatase 2A, induces c-Jun and AP-1 activity Biochemical Journal. 341: 293-298. DOI: 10.1042/0264-6021:3410293  1
1998 Coffer PJ, Jin J, Woodgett JR. Protein kinase B (c-Akt): A multifunctional mediator of phosphatidylinositol 3-kinase activation Biochemical Journal. 335: 1-13. PMID 9742206 DOI: 10.1042/Bj3350001  1
1998 Staveley BE, Ruel L, Jin J, Stambolic V, Mastronardi FG, Heitzler P, Woodgett JR, Manoukian AS. Genetic analysis of protein kinase B (AKT) in Drosophila Current Biology. 8: 599-602. PMID 9601646 DOI: 10.1016/S0960-9822(98)70231-3  1
1998 May GH, Funk M, Black EJ, Clark W, Hussain S, Woodgett JR, Gillespie DA. An oncogenic mutation uncouples the v-Jun oncoprotein from positive regulation by the SAPK/JNK pathway in vivo. Current Biology : Cb. 8: 117-20. PMID 9427647 DOI: 10.1016/S0960-9822(98)70043-0  1
1997 Gutstein HB, Rubie EA, Mansour A, Akil H, Woodgett JR. Opioid effects on mitogen-activated protein kinase signaling cascades. Anesthesiology. 87: 1118-26. PMID 9366464 DOI: 10.1097/00000542-199711000-00016  1
1997 Brownlees J, Irving NG, Brion JP, Gibb BJ, Wagner U, Woodgett J, Miller CC. Tau phosphorylation in transgenic mice expressing glycogen synthase kinase-3beta transgenes. Neuroreport. 8: 3251-5. PMID 9351652 DOI: 10.1097/00001756-199710200-00013  1
1997 Nishina H, Bachmann M, Oliveira-dos-Santos AJ, Kozieradzki I, Fischer KD, Odermatt B, Wakeham A, Shahinian A, Takimoto H, Bernstein A, Mak TW, Woodgett JR, Ohashi PS, Penninger JM. Impaired CD28-mediated interleukin 2 production and proliferation in stress kinase SAPK/ERK1 kinase (SEK1)/mitogen-activated protein kinase kinase 4 (MKK4)-deficient T lymphocytes. The Journal of Experimental Medicine. 186: 941-53. PMID 9294148 DOI: 10.1084/Jem.186.6.941  1
1997 Hansen L, Arden KC, Rasmussen SB, Viars CS, Vestergaard H, Hansen T, Møller AM, Woodgett JR, Pedersen O. Chromosomal mapping and mutational analysis of the coding region of the glycogen synthase kinase-3α and β isoforms in patients with NIDDM Diabetologia. 40: 940-946. PMID 9267989 DOI: 10.1007/S001250050771  1
1997 Kiefer F, Tibbles LA, Lassamt N, Zanke B, Iscove N, Woodgett JR. Novel components of mammalian stress-activated protein kinase cascades Biochemical Society Transactions. 25: 491-498. PMID 9191142 DOI: 10.1042/Bst0250491  1
1997 Shrode LD, Rubie EA, Woodgett JR, Grinstein S. Cytosolic alkalinization increases stress-activated protein kinase/c- Jun NH2-terminal kinase (SAPK/JNK) activity and p38 mitogen-activated protein kinase activity by a calcium-independent mechanism Journal of Biological Chemistry. 272: 13653-13659. PMID 9153215 DOI: 10.1074/Jbc.272.21.13653  1
1997 Nishina H, Fischer KD, Radvanyi L, Shahinian A, Hakem R, Rubie EA, Bernstein A, Mak TW, Woodgett JR, Penninger JM. Stress-signalling kinase Sek1 protects thymocytes from apoptosis mediated by CD95 and CD3. Nature. 385: 350-3. PMID 9002521 DOI: 10.1038/385350A0  1
1997 Natoli G, Costanzo A, Ianni A, Templeton DJ, Woodgett JR, Balsano C, Levrero M. Activation of SAPK/JNK by TNF receptor 1 through a noncytotoxic TRAF2- dependent pathway Science. 275: 200-203. PMID 8985011 DOI: 10.1126/Science.275.5297.200  1
1996 Tibbles LA, Ing YL, Kiefer F, Chan J, Iscove N, Woodgett JR, Lassam NJ. MLK-3 activates the SAPK/JNK and p38/RK pathways via SEK1 and MKK3/6 Embo Journal. 15: 7026-7035. PMID 9003778  1
1996 Kiefer F, Tibbles LA, Anafi M, Janssen A, Zanke BW, Lassam N, Pawson T, Woodgett JR, Iscove NN. HPK1, a hematopoietic protein kinase activating the SAPK/JNK pathway Embo Journal. 15: 7013-7025. PMID 9003777 DOI: 10.1002/J.1460-2075.1996.Tb01093.X  1
1996 Stambolic V, Ruel L, Woodgett JR. Lithium inhibits glycogen synthase kinase-3 activity and mimics wingless signalling in intact cells Current Biology. 6: 1664-1668. PMID 8994831 DOI: 10.1016/S0960-9822(02)70790-2  1
1996 Zanke BW, Rubie EA, Winnett E, Chan J, Randall S, Parsons M, Boudreau K, McInnis M, Yan M, Templeton DJ, Woodgett JR. Mammalian mitogen-activated protein kinase pathways are regulated through formation of specific kinase-activator complexes. The Journal of Biological Chemistry. 271: 29876-81. PMID 8939929 DOI: 10.1074/Jbc.271.47.29876  1
1996 Woodgett JR, Avruch J, Kyriakis J. The stress activated protein kinase pathway Cancer Surveys. 27: 127-138. PMID 8909798  1
1996 Cook D, Fry MJ, Hughes K, Sumathipala R, Woodgett JR, Dale TC. Wingless inactivates glycogen synthase kinase-3 via an intracellular signalling pathway which involves a protein kinase C. The Embo Journal. 15: 4526-36. PMID 8887544  1
1996 Zanke BW, Boudreau K, Rubie E, Winnett E, Tibbles LA, Zon L, Kyriakis J, Liu FF, Woodgett JR. The stress-activated protein kinase pathway mediates cell death following injury induced by cis-platinum, UV irradiation or heat Current Biology. 6: 606-613. PMID 8805279 DOI: 10.1016/S0960-9822(02)00547-X  1
1996 Woodgett JR. Reconstitution of novel signalling cascades responding to cellular stresses Philosophical Transactions of the Royal Society B: Biological Sciences. 351: 135-142. PMID 8650259 DOI: 10.1098/Rstb.1996.0009  1
1996 Guidato S, Tsai LH, Woodgett J, Miller CC. Differential cellular phosphorylation of neurofilament heavy side-arms by glycogen synthase kinase-3 and cyclin-dependent kinase-5. Journal of Neurochemistry. 66: 1698-706. PMID 8627328 DOI: 10.1046/J.1471-4159.1996.66041698.X  0.08
1996 Nunes JA, Battifora M, Woodgett JR, Truneh A, Olive D, Cantrell DA. CD28 signal transduction pathways. A comparison of B7-1 and B7-2 regulation of the map kinases: ERK2 and Jun kinases. Molecular Immunology. 33: 63-70. PMID 8604225 DOI: 10.1016/0161-5890(95)00121-2  1
1996 Berberich I, Shu G, Siebelt F, Woodgett JR, Kyriakis JM, Clark EA. Cross-linking CD40 on B cells preferentially induces stress-activated protein kinases rather than mitogen-activated protein kinases Embo Journal. 15: 92-101. PMID 8598210 DOI: 10.1002/J.1460-2075.1996.Tb00337.X  1
1996 Plyte SE, Feoktistova A, Burke JD, Woodgett JR, Gould KL. Schizosaccharomyces pombe skp1+ encodes a protein kinase related to mammalian glycogen synthase kinase 3 and complements a cdc14 cytokinesis mutant Molecular and Cellular Biology. 16: 179-191. PMID 8524294 DOI: 10.1128/mcb.16.1.179  1
1996 Tibbles LA, Ing YL, Kiefer F, Chan J, Iscove N, Woodgett JR, Lassam NJ. Mlk-3 Activates The Sapk/Jnk And P38/Rk Pathways Via Sek1 And Mkk3/6 The Embo Journal. 15: 7026-7035. DOI: 10.1002/J.1460-2075.1996.Tb01094.X  1
1995 Baum L, Seger R, Woodgett JR, Kawabata S, Maruyama K, Koyama M, Silver J, Saitoh T. Overexpressed tau protein in cultured cells is phosphorylated without formation of PHF: implication of phosphoprotein phosphatase involvement Molecular Brain Research. 34: 1-17. PMID 8750856 DOI: 10.1016/0169-328X(95)00111-5  1
1995 Dai T, Rubie E, Franklin CC, Kraft A, Gillespie DAF, Avruch J, Kyriakis JM, Woodgett JR. Stress-activated protein kinases bind directly to the δ domain of c-Jun in resting cells: Implications for repression of c-Jun function Oncogene. 10: 849-855. PMID 7898927  1
1995 Coso OA, Chiariello M, Kalinec G, Kyriakis JM, Woodgett J, Gutkind JS. Transforming G protein-coupled receptors potently activate JNK (SAPK): Evidence for a divergence from the tyrosine kinase signaling pathway Journal of Biological Chemistry. 270: 5620-5624. PMID 7890682 DOI: 10.1074/Jbc.270.10.5620  1
1995 Harwood AJ, Plyte SE, Woodgett J, Strutt H, Kay RR. Glycogen synthase kinase 3 regulates cell fate in Dictyostelium. Cell. 80: 139-48. PMID 7813009 DOI: 10.1016/0092-8674(95)90458-1  1
1995 Latimer DA, Gallo JM, Lovestone S, Miller CC, Reynolds CH, Marquardt B, Stabel S, Woodgett JR, Anderton BH. Stimulation of MAP kinase by v-raf transformation of fibroblasts fails to induce hyperphosphorylation of transfected tau. Febs Letters. 365: 42-6. PMID 7774712 DOI: 10.1016/0014-5793(95)00434-B  1
1995 Mulot SF, Hughes K, Woodgett JR, Anderton BH, Hanger DP. Phosphorylation of tau by glycogen synthase kinase-3 beta in vitro produces species with similar electrophoretic and immunogenic properties to PHF-tau from Alzheimer's disease brain. Biochemical Society Transactions. 23: 45S. PMID 7758758 DOI: 10.1042/Bst023045S  1
1995 He X, Saint-Jeannet JP, Woodgett JR, Varmus HE, Dawid IB. Glycogen synthase kinase-3 and dorsoventral patterning in Xenopus embryos. Nature. 374: 617-22. PMID 7715701 DOI: 10.1038/374617A0  1
1995 Woodgett JR, Avruch J, Kyriakis JM. Regulation of nuclear transcription factors by stress signals Clinical and Experimental Pharmacology and Physiology. 22: 281-283. PMID 7671441 DOI: 10.1111/J.1440-1681.1995.Tb01995.X  1
1995 Kyriakis JM, Woodgett JR, Avruch J. The stress-activated protein kinases. A novel ERK subfamily responsive to cellular stress and inflammatory cytokines Annals of the New York Academy of Sciences. 766: 303-319. PMID 7486678 DOI: 10.1111/J.1749-6632.1995.Tb26683.X  1
1995 Pombo CM, Kehrl JH, Sánchez I, Katz P, Avruch J, Zon LI, Woodgett JR, Force T, Kyriakis JM. Activation of the SAPK pathway by the human STE20 homologue germinal centre kinase Nature. 377: 750-754. PMID 7477268 DOI: 10.1038/377750A0  1
1994 Pulverer BJ, Fisher C, Vousden K, Littlewood T, Evan G, Woodgett JR. Site-specific modulation of c-Myc cotransformation by residues phosphorylated in vivo Oncogene. 9: 59-70. PMID 8302604  1
1994 Coffer PJ, Woodgett JR. Differential Subcellular Localization of Two Isoforms of p70 S6 Protein Kinase Biochemical and Biophysical Research Communications. 198: 780-786. PMID 8297390 DOI: 10.1006/Bbrc.1994.1112  1
1994 Kyriakis JM, Banerjee P, Nikolakaki E, Dai T, Rubie EA, Ahmad MF, Avruch J, Woodgett JR. The stress-activated protein kinase subfamily of c-Jun kinases Nature. 369: 156-160. PMID 8177321 DOI: 10.1038/369156A0  1
1994 Woodgett JR, Pulverer BJ, Plyte S, Hughes K, Nikolakaki E. Nuclear onco-protein targets of signal transduction pathways Pigment Cell Research / Sponsored by the European Society For Pigment Cell Research and the International Pigment Cell Society. 7: 96-100. PMID 8066026 DOI: 10.1111/J.1600-0749.1994.Tb00027.X  1
1994 Mulot SF, Hughes K, Woodgett JR, Anderton BH, Hanger DP. PHF-tau from Alzheimer's brain comprises four species on SDS-PAGE which can be mimicked by in vitro phosphorylation of human brain tau by glycogen synthase kinase-3 beta. Febs Letters. 349: 359-64. PMID 8050597 DOI: 10.1016/0014-5793(94)00702-0  1
1994 Black EJ, Catling AD, Woodgett JR, Kilbey A, Gillespie DA. Transcriptional activation by the v-Jun oncoprotein is independent of positive regulatory phosphorylation. Oncogene. 9: 2363-8. PMID 8036019  1
1994 Yan M, Dai T, Deak JC, Kyriakis JM, Zon LI, Woodgett JR, Templeton DJ. Activation of stress-activated protein kinase by MEKK1 phosphorylation of its activator SEK1 Nature. 372: 798-800. PMID 7997270 DOI: 10.1038/372798A0  1
1994 Sánchez I, Hughes RT, Mayer BJ, Yee K, Woodgett JR, Avruch J, Kyriakis JM, Zon LI. Role of SAPK/ERK kinase-1 in the stress-activated pathway regulating transcription factor c-Jun. Nature. 372: 794-8. PMID 7997269 DOI: 10.1038/372794A0  1
1994 Stambolic V, Woodgett JR. Mitogen inactivation of glycogen synthase kinase-3β in intact cells via serine 9 phosphorylation Biochemical Journal. 303: 701-704. PMID 7980435 DOI: 10.1042/Bj3030701  1
1994 Pombo CM, Bonventre JV, Avruch J, Woodgett JR, Kyriakis JM, Force T. The stress-activated protein kinases are major c-Jun amino-terminal kinases activated by ischemia and reperfusion Journal of Biological Chemistry. 269: 26546-26551. PMID 7929379  1
1994 Benjamin WB, Pentyala SN, Woodgett JR, Hod Y, Marshak D. ATP citrate-lyase and glycogen synthase kinase-3β in 3T3-L1 cells during differentiation into adipocytes Biochemical Journal. 300: 477-482. PMID 7911658 DOI: 10.1042/Bj3000477  1
1994 Woodgett JR. Regulation and functions of the glycogen synthase kinase-3 subfamily Seminars in Cancer Biology. 5: 269-275. PMID 7803763  1
1994 Lovestone S, Reynolds CH, Latimer D, Davis DR, Anderton BH, Gallo JM, Hanger D, Mulot S, Marquardt B, Stabel S. Alzheimer's disease-like phosphorylation of the microtubule-associated protein tau by glycogen synthase kinase-3 in transfected mammalian cells. Current Biology : Cb. 4: 1077-86. PMID 7704571 DOI: 10.1016/S0960-9822(00)00246-3  1
1994 Bianchi MW, Guivarc'h D, Thomas M, Woodgett JR, Kreis M. Arabidopsis homologs of the shaggy and GSK-3 protein kinases: molecular cloning and functional expression in Escherichia coli Mgg Molecular &Amp; General Genetics. 242: 337-345. PMID 7509023 DOI: 10.1007/Bf00280424  1
1993 Pulverer BJ, Hughes K, Franklin CC, Kraft AS, Leevers SJ, Woodgett JR. Co-purification of mitogen-activated protein kinases with phorbol ester-induced c-Jun kinase activity in U937 leukaemic cells Oncogene. 8: 407-415. PMID 8426747  1
1993 Woodgett JR, Pulverer BJ, Nikolakaki E, Plyte S, Hughes K, Franklin CC, Kraft AS. Regulation of jun/AP-1 oncoproteins by protein phosphorylation Advances in Second Messenger and Phosphoprotein Research. 28: 261-269. PMID 8398412  1
1993 Nikolakaki E, Coffer PJ, Hemelsoet R, Woodgett JR, Defize LHK. Glycogen synthase kinase 3 phosphorylates Jun family members in vitro and negatively regulates their transactivating potential in intact cells Oncogene. 8: 833-840. PMID 8384354  1
1993 Hughes K, Nikolakaki E, Plyte SE, Totty NF, Woodgett JR. Modulation of the glycogen synthase kinase-3 family by tyrosine phosphorylation Embo Journal. 12: 803-808. PMID 8382613 DOI: 10.1002/J.1460-2075.1993.Tb05715.X  1
1993 Bianchi MW, Plyte SE, Kreis M, Woodgett JR. A Saccharomyces cerevisiae protein-serine kinase related to mammalian glycogen synthase kinase-3 and the Drosophila melanogaster gene shaggy product Gene. 134: 51-56. PMID 8244030 DOI: 10.1016/0378-1119(93)90173-Z  1
1993 Woodgett JR, Plyte SE, Pulverer BJ, Mitchell JA, Hughes K. Roles of glycogen synthase kinase-3 in signal transduction Biochemical Society Transactions. 21: 905-907. PMID 8147970 DOI: 10.1042/Bst0210905  1
1993 Woodgett JR. A kinase with Ku-dos Current Biology. 3: 450. DOI: 10.1016/0960-9822(93)90353-P  1
1992 Prigent C, Lasko DD, Kodama KI, Woodgett JR, Lindahl T. Activation of mammalian DNA ligase I through phosphorylation by casein kinase II Embo Journal. 11: 2925-2933. PMID 1639065 DOI: 10.1002/J.1460-2075.1992.Tb05362.X  1
1992 Coffer PJ, Woodgett JR. Molecular cloning and characterisation of a novel putative protein-serine kinase related to the cAMP-dependent and protein kinase C families. European Journal of Biochemistry. 205: 1217. PMID 1533586  1
1992 Franklin CC, Sanchez V, Wagner F, Woodgett JR, Kraft AS. Phorbol ester-induced amino-terminal phosphorylation of human JUN but not JUNB regulates transcriptional activation Proceedings of the National Academy of Sciences of the United States of America. 89: 7247-7251. PMID 1496019 DOI: 10.1073/Pnas.89.15.7247  1
1992 Hughes K, Pulverer BJ, Theocharous P, Woodgett JR. Baculovirus-mediated expression and characterisation of rat glycogen synthase kinase-3β, the mammalian homologue of the Drosophila melanogaster zeste-white3(sgg) homeotic gene product European Journal of Biochemistry. 203: 305-311. PMID 1346104 DOI: 10.1111/J.1432-1033.1992.Tb19860.X  1
1992 Hanger DP, Hughes K, Woodgett JR, Brion JP, Anderton BH. Glycogen synthase kinase-3 induces Alzheimer's disease-like phosphorylation of tau: generation of paired helical filament epitopes and neuronal localisation of the kinase. Neuroscience Letters. 147: 58-62. PMID 1336152 DOI: 10.1016/0304-3940(92)90774-2  1
1992 Plyte SE, Hughes K, Nikolakaki E, Pulverer BJ, Woodgett JR. Glycogen synthase kinase-3: functions in oncogenesis and development Bba - Reviews On Cancer. 1114: 147-162. PMID 1333807 DOI: 10.1016/0304-419X(92)90012-N  1
1992 Hughes K, Ramakrishna S, Benjamin WB, Woodgett JR. Identification of multifunctional ATP-citrate lyase kinase as the α-isoform of glycogen synthase kinase-3 Biochemical Journal. 288: 309-314. PMID 1332698 DOI: 10.1042/Bj2880309  1
1992 Goode N, Hughes K, Woodgett JR, Parker PJ. Differential regulation of glycogen synthase kinase-3β by protein kinase C isotypes Journal of Biological Chemistry. 267: 16878-16882. PMID 1324914  1
1992 Saksela K, Mäkelä TP, Hughes K, Woodgett JR, Alitalo K. Activation of protein kinase C increases phosphorylation of the L-myc trans-activator domain at a GSK-3 target site Oncogene. 7: 347-353. PMID 1312697  1
1992 Woodgett JR. Finding the stepping stones downstream of ras Current Biology. 2: 357-358. DOI: 10.1016/0960-9822(92)90060-N  1
1991 Pulverer BJ, Kyriakis JM, Avruch J, Nikolakaki E, Woodgett JR. Phosphorylation of c-jun mediated by MAP kinases Nature. 353: 670-674. PMID 1922387 DOI: 10.1038/353670A0  1
1991 Grove JR, Banerjee P, Balasubramanyam A, Coffer PJ, Price DJ, Avruch J, Woodgett JR. Cloning and expression of two human p70 S6 kinase polypeptides differing only at their amino termini. Molecular and Cellular Biology. 11: 5541-50. PMID 1922062 DOI: 10.1128/mcb.11.11.5541-5550.1991  1
1991 Ragsdale C, Woodgett J. Neurobiology. trking neurotrophic receptors. Nature. 350: 660-1. PMID 1850820 DOI: 10.1038/350660A0  1
1991 Boyle WJ, Smeal T, Defize LHK, Angel P, Woodgett JR, Karin M, Hunter T. Activation of protein kinase C decreases phosphorylation of c-Jun at sites that negatively regulate its DNA-binding activity Cell. 64: 573-584. PMID 1846781 DOI: 10.1016/0092-8674(91)90241-P  1
1991 Coffer PJ, Woodgett JR. Molecular cloning and characterisation of a novel putative protein-serine kinase related to the cAMP-dependent and protein kinase C families European Journal of Biochemistry. 201: 475-481. PMID 1718748 DOI: 10.1111/J.1432-1033.1991.Tb16305.X  1
1991 Woodgett JR. cDNA cloning and properties of glycogen synthase kinase-3 Methods in Enzymology. 200: 564-577. PMID 1659660 DOI: 10.1016/0076-6879(91)00172-S  1
1991 Woodgett JR. Use of synthetic peptides mimicking phosphorylation sites for affinity purification of protein-serine kinases Methods in Enzymology. 200: 169-178. PMID 1659651 DOI: 10.1016/0076-6879(91)00137-L  1
1991 Jang Kl, Pulverer B, Woodgett JR, Latchman DS. Activation of the cellular transcription factor AP-1 in herpes simplex virus infected cells is dependent on the viral immediate-early protein ICPO Nucleic Acids Research. 19: 4879-4883. PMID 1656381 DOI: 10.1093/Nar/19.18.4879  1
1991 Woodgett JR. A common denominator linking glycogen metabolism, nuclear oncogenes and development Trends in Biochemical Sciences. 16: 177-181. PMID 1652801 DOI: 10.1016/0968-0004(91)90071-3  1
1991 Woodgett JR. Powering the cell cycle Current Biology. 1: 106-107. DOI: 10.1016/0960-9822(91)90293-6  1
1990 Woodgett JR. Path-ology: The cartography of life New Biologist. 2: 244-248. PMID 2279028  1
1990 Woodgett JR. Molecular cloning expression of glycogen synthase kinase-3/Factor A Embo Journal. 9: 2431-2438. PMID 2164470  1
1990 Woodgett JR. Fos and jun: Two into one will go Seminars in Cancer Biology. 1: 389-397. PMID 2129427  1
1990 Marais RM, Nguyen O, Woodgett JR, Parker PJ. Studies on the primary sequence requirements for PKC-α, -β1 and -γ peptide substrates Febs Letters. 277: 151-155. PMID 1702730 DOI: 10.1016/0014-5793(90)80831-3  1
1989 Woodgett JR. Early gene induction by growh factors British Medical Bulletin. 45: 529-540. PMID 2688816 DOI: 10.1093/Oxfordjournals.Bmb.A072340  1
1989 Woodgett JR. Telling the players without a scorecard. Gene Cascades and Second Messengers in Cancer Sponsored by the Research Institute of Molecular Pathology, Vienna, Austria, May 20-22, 1989 The New Biologist. 1: 24-27. PMID 2577343  1
1989 Woodgett JR. Use of peptide substrates for affinity purification of protein-serine kinases Analytical Biochemistry. 180: 237-241. PMID 2554753 DOI: 10.1016/0003-2697(89)90423-5  1
1987 Woodgett JR, Hunter T. Regulation of protein kinase C by activators, Ca2+, and phosphorylation Progress in Clinical and Biological Research. 249: 237-247. PMID 3671427  1
1987 Woodgett JR, Hunter T. Immunological evidence for two physiological forms of protein kinase C Molecular and Cellular Biology. 7: 85-96. PMID 3561403 DOI: 10.1128/Mcb.7.1.85  1
1987 Woodgett JR, Hunter T. Isolation and characterization of two distinct forms of protein kinase C Journal of Biological Chemistry. 262: 4836-4843. PMID 3558373  1
1987 Bilezikjian LM, Woodgett JR, Hunter T, Vale WW. Phorbol ester-induced down-regulation of protein kinase C abolishes vasopressin-mediated responses in rat anterior pituitary cells Molecular Endocrinology (Baltimore, Md.). 1: 555-560. PMID 3153477 DOI: 10.1210/Mend-1-8-555  1
1986 Woodgett JR, Gould KL, Hunter T. Substrate specificity of protein kinase C - Use of synthetic peptides corresponding to physiological sites as probes for substrate recognition requirements European Journal of Biochemistry. 161: 177-184. PMID 3023081 DOI: 10.1111/J.1432-1033.1986.Tb10139.X  1
1986 Gould KL, Woodgett JR, Isacke CM, Hunter T. The protein-tyrosine kinase substrate p36 is also a substrate for protein kinase C in vitro and in vivo Molecular and Cellular Biology. 6: 2738-2744. PMID 2946940 DOI: 10.1128/Mcb.6.7.2738  1
1985 Pearson RB, Woodgett JR, Cohen P, Kemp BE. Substrate specificity of a multifunctional calmodulin-dependent protein kinase. The Journal of Biological Chemistry. 260: 14471-6. PMID 4055784  1
1985 Kuret J, Woodgett JR, Cohen P. Multisite phosphorylation of glycogen synthase from rabbit skeletal muscle. Identification of the sites phosphorylated by casein kinase-I. European Journal of Biochemistry / Febs. 151: 39-48. PMID 3928373 DOI: 10.1111/J.1432-1033.1985.Tb09066.X  1
1985 Gould KL, Woodgett JR, Cooper JA, Buss JE, Shalloway D, Hunter T. Protein kinase C phosphorylates pp60src at a novel site Cell. 42: 849-857. PMID 2996780 DOI: 10.1016/0092-8674(85)90281-8  1
1985 Vulliet PR, Woodgett JR, Ferrari S, Hardie DG. Characterization of the sites phosphorylated on tyrosine hydroxylase by Ca2+ and phospholipid-dependent protein kinase, calmodulin-dependent multiprotein kinase and cyclic AMP-dependent protein kinase. Febs Letters. 182: 335-9. PMID 2858405 DOI: 10.1016/0014-5793(85)80328-8  1
1984 Woodgett JR, Cohen P, Yamauchi T, Fujisawa H. Comparison of calmodulin-dependent glycogen synthase kinase from skeletal muscle and calmodulin-dependent protein kinase-II from brain. Febs Letters. 170: 49-54. PMID 6327377 DOI: 10.1016/0014-5793(84)81366-6  1
1984 Vulliet PR, Woodgett JR, Cohen P. Phosphorylation of tyrosine hydroxylase by calmodulin-dependent multiprotein kinase. The Journal of Biological Chemistry. 259: 13680-3. PMID 6150037  1
1984 Woodgett JR, Cohen P. Multisite phosphorylation of glycogen synthase. Molecular basis for the substrate specificity of glycogen synthase kinase-3 and casein kinase-II (glycogen synthase kinase-5). Biochimica Et Biophysica Acta. 788: 339-47. PMID 6087911 DOI: 10.1016/0167-4838(84)90047-5  1
1983 McGuinness TL, Lai Y, Greengard P, Woodgett JR, Cohen P. A multifunctional calmodulin-dependent protein kinase. Similarities between skeletal muscle glycogen synthase kinase and a brain synapsin I kinase. Febs Letters. 163: 329-34. PMID 6315492 DOI: 10.1016/0014-5793(83)80846-1  1
1983 Woodgett JR, Davison MT, Cohen P. The calmodulin-dependent glycogen synthase kinase from rabbit skeletal muscle. Purification, subunit structure and substrate specificity. European Journal of Biochemistry / Febs. 136: 481-7. PMID 6315430 DOI: 10.1111/J.1432-1033.1983.Tb07766.X  1
1983 Holland R, Woodgett JR, Hardie DG. Evidence that amiloride antagonises insulin-stimulated protein phosphorylation by inhibiting protein kinase activity Febs Letters. 154: 269-273. PMID 6299802 DOI: 10.1016/0014-5793(83)80163-X  1
1982 Picton C, Woodgett J, Hemmings B, Cohen P. Multisite phosphorylation of glycogen synthase from rabbit skeletal muscle. Phosphorylation of site 5 by glycogen synthase kinase-5 (casein kinase-II) is a prerequisite for phosphorylation of sites 3 by glycogen synthase kinase-3. Febs Letters. 150: 191-196. PMID 6819160 DOI: 10.1016/0014-5793(82)81332-X  1
1982 Picton C, Aitken A, Bilham T, Cohen P. Multisite phosphorylation of glycogen synthase from rabbit skeletal muscle. Organisation of the seven sites in the polypeptide chain. European Journal of Biochemistry. 124: 37-45. PMID 6806097 DOI: 10.1111/J.1432-1033.1982.Tb05903.X  0.44
1982 Woodgett JR, Tonks NK, Cohen P. Identification of a calmodulin-dependent glycogen synthase kinase in rabbit skeletal muscle, distinct from phosphorylase kinase. Febs Letters. 148: 5-11. PMID 6293876 DOI: 10.1016/0014-5793(82)81231-3  1
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