Cheryl Arrowsmith - Publications

Affiliations: 
Medical Biophysics University of Toronto, Toronto, ON, Canada 
Area:
General Biophysics, Biochemistry

162 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Münzker L, Kimani SW, Fowkes MM, Dong A, Zheng H, Li Y, Dasovich M, Zak KM, Leung AKL, Elkins JM, Kessler D, Arrowsmith CH, Halabelian L, Böttcher J. A ligand discovery toolbox for the WWE domain family of human E3 ligases. Communications Biology. 7: 901. PMID 39048679 DOI: 10.1038/s42003-024-06584-w  0.316
2021 Dilworth D, Hanley RP, Ferreira de Freitas R, Allali-Hassani A, Zhou M, Mehta N, Marunde MR, Ackloo S, Carvalho Machado RA, Khalili Yazdi A, Owens DDG, Vu V, Nie DY, Alqazzaz M, Marcon E, ... ... Arrowsmith CH, et al. A chemical probe targeting the PWWP domain alters NSD2 nucleolar localization. Nature Chemical Biology. PMID 34782742 DOI: 10.1038/s41589-021-00898-0  0.315
2021 Mann MK, Zepeda-Velázquez CA, González-Álvarez H, Dong A, Kiyota T, Aman AM, Loppnau P, Li Y, Wilson B, Arrowsmith CH, Al-Awar R, Harding RJ, Schapira M. Structure-Activity Relationship of USP5 Inhibitors. Journal of Medicinal Chemistry. PMID 34648286 DOI: 10.1021/acs.jmedchem.1c00889  0.308
2021 Dölle A, Adhikari B, Krämer A, Weckesser J, Berner N, Berger LM, Diebold M, Szewczyk MM, Barsyte-Lovejoy D, Arrowsmith CH, Gebel J, Löhr F, Dötsch V, Eilers M, Heinzlmeir S, et al. Design, Synthesis, and Evaluation of WD-Repeat-Containing Protein 5 (WDR5) Degraders. Journal of Medicinal Chemistry. PMID 33980013 DOI: 10.1021/acs.jmedchem.1c00146  0.306
2021 Ferreira de Freitas R, Liu Y, Szewczyk MM, Mehta N, Li F, McLeod D, Zepeda-Velázquez C, Dilworth D, Hanley RP, Gibson E, Brown PJ, Al-Awar R, James LI, Arrowsmith CH, Barsyte-Lovejoy D, et al. Discovery of Small-Molecule Antagonists of the PWWP Domain of NSD2. Journal of Medicinal Chemistry. PMID 33522809 DOI: 10.1021/acs.jmedchem.0c01768  0.3
2020 Tauber M, Kreuz S, Lemak A, Mandal P, Yerkesh Z, Veluchamy A, Al-Gashgari B, Aljahani A, Cortés-Medina LV, Azhibek D, Fan L, Ong MS, Duan S, Houliston S, Arrowsmith CH, et al. Alternative splicing and allosteric regulation modulate the chromatin binding of UHRF1. Nucleic Acids Research. PMID 32609811 DOI: 10.1093/nar/gkaa520  0.333
2019 Arrowsmith CH, Schapira M. Targeting non-bromodomain chromatin readers. Nature Structural & Molecular Biology. 26: 863-869. PMID 31582844 DOI: 10.1038/s41594-019-0290-2  0.308
2019 Mader P, Mendoza-Sanchez R, Iqbal A, Dong A, Dobrovetsky E, Corless VB, Liew SK, Houliston SR, De Freitas RF, Smil D, Sena CCD, Kennedy S, Diaz DB, Wu H, Dombrovski L, ... ... Arrowsmith CH, et al. Identification and characterization of the first fragment hits for SETDB1 Tudor domain. Bioorganic & Medicinal Chemistry. PMID 31327677 DOI: 10.1016/J.Bmc.2019.07.020  0.312
2019 Krug B, De Jay N, Harutyunyan AS, Deshmukh S, Marchione DM, Guilhamon P, Bertrand KC, Mikael LG, McConechy MK, Chen CCL, Khazaei S, Koncar RF, Agnihotri S, Faury D, Ellezam B, ... ... Arrowsmith C, et al. Pervasive H3K27 Acetylation Leads to ERV Expression and a Therapeutic Vulnerability in H3K27M Gliomas. Cancer Cell. 35: 782-797.e8. PMID 31085178 DOI: 10.1016/J.Ccell.2019.04.004  0.32
2018 Ivanochko D, Halabelian L, Henderson E, Savitsky P, Jain H, Marcon E, Duan S, Hutchinson A, Seitova A, Barsyte-Lovejoy D, Filippakopoulos P, Greenblatt J, Lima-Fernandes E, Arrowsmith CH. Direct interaction between the PRDM3 and PRDM16 tumor suppressors and the NuRD chromatin remodeling complex. Nucleic Acids Research. PMID 30462309 DOI: 10.1093/Nar/Gky1192  0.33
2018 Senisterra G, Zhu HY, Luo X, Zhang H, Xun G, Lu C, Xiao W, Hajian T, Loppnau P, Chau I, Li F, Allali-Hassani A, Atadja P, Oyang C, Li E, ... ... Arrowsmith CH, et al. Discovery of Small-Molecule Antagonists of the H3K9me3 Binding to UHRF1 Tandem Tudor Domain. Slas Discovery : Advancing Life Sciences R & D. 2472555218766278. PMID 29562800 DOI: 10.1177/2472555218766278  0.34
2017 Schapira M, Tyers M, Torrent M, Arrowsmith CH. WD40 repeat domain proteins: a novel target class? Nature Reviews. Drug Discovery. PMID 29026209 DOI: 10.1038/Nrd.2017.179  0.311
2017 He Y, Selvaraju S, Curtin ML, Jakob CG, Zhu H, Comess KM, Shaw B, The J, Lima-Fernandes E, Szewczyk MM, Cheng D, Klinge KL, Li HQ, Pliushchev M, Algire MA, ... ... Arrowsmith CH, et al. The EED protein-protein interaction inhibitor A-395 inactivates the PRC2 complex. Nature Chemical Biology. PMID 28135237 DOI: 10.1038/Nchembio.2306  0.322
2017 Valleau D, Houliston S, Lemak A, Anderson WF, Arrowsmith C, Savchenko A. Solution structure of the N-terminal domain of the effector NleG5-1 from Escherichia coli O157:H7 str. Sakai Journal of Back and Musculoskeletal Rehabilitation. DOI: 10.2210/Pdb6B3N/Pdb  0.332
2017 Hartung IV, Arrowsmith C, Badock V, Barak N, Berger M, Brown PJ, Christ CD, Eggert E, Egner U, Fedorov O, Fernandez-Montalvan AE, Gorjanacz M, Haegebarth A, Haendler B, Hillig RC, et al. Abstract 5239: Probing the cancer epigenome: empowering target validation by open innovation Cancer Research. 77: 5239-5239. DOI: 10.1158/1538-7445.Am2017-5239  0.357
2017 Rocklin GJ, Chidyausiku T, Goreshnik I, Ford A, Houliston S, Arrowsmith C, Baker D. High-Throughput Protein Design Reveals Quantitative Protein Stability Requirements Biophysical Journal. 112: 194a. DOI: 10.1016/J.Bpj.2016.11.1076  0.327
2016 Korzhnev DM, Neculai D, Dhe-Paganon S, Arrowsmith CH, Bezsonova I. Solution NMR structure of the HLTF HIRAN domain: a conserved module in SWI2/SNF2 DNA damage tolerance proteins. Journal of Biomolecular Nmr. PMID 27771863 DOI: 10.1007/s10858-016-0070-9  0.348
2016 Blazer LL, Lima-Fernandes E, Gibson E, Eram MS, Loppnau P, Arrowsmith CH, Schapira M, Vedadi M. PR Domain-Containing Protein 7 (PRDM7) is a Histone 3 Lysine 4 Trimethyltransferase. The Journal of Biological Chemistry. PMID 27129774 DOI: 10.1074/jbc.M116.721472  0.324
2016 Ferreira de Freitas R, Eram MS, Szewczyk MM, Steuber H, Smil D, Wu H, Li F, Senisterra G, Dong A, Brown PJ, Hitchcock M, Moosmayer D, Stegmann CM, Egner U, Arrowsmith C, et al. Discovery of a Potent Class I Protein Arginine Methyltransferase Fragment Inhibitor. Journal of Medicinal Chemistry. PMID 26824386 DOI: 10.1021/Acs.Jmedchem.5B01772  0.372
2015 Perfetti MT, Baughman BM, Dickson BM, Mu Y, Cui G, Mader P, Dong A, Norris JL, Rothbart SB, Strahl BD, Brown PJ, Janzen WP, Arrowsmith CH, Mer G, McBride KM, et al. Identification of a fragment-like small molecule ligand for the methyl-lysine binding protein, 53BP1. Acs Chemical Biology. 10: 1072-81. PMID 25590533 DOI: 10.1021/Cb500956G  0.349
2015 Hong JH, Kaustov L, Coyaud E, Srikumar T, Wan J, Arrowsmith C, Raught B. KCMF1 (potassium channel modulatory factor 1) Links RAD6 to UBR4 (ubiquitin N-recognin domain-containing E3 ligase 4) and lysosome-mediated degradation. Molecular & Cellular Proteomics : McP. 14: 674-85. PMID 25582440 DOI: 10.1074/Mcp.M114.042168  0.371
2014 Gelato KA, Tauber M, Ong MS, Winter S, Hiragami-Hamada K, Sindlinger J, Lemak A, Bultsma Y, Houliston S, Schwarzer D, Divecha N, Arrowsmith CH, Fischle W. Accessibility of different histone H3-binding domains of UHRF1 is allosterically regulated by phosphatidylinositol 5-phosphate. Molecular Cell. 54: 905-19. PMID 24813945 DOI: 10.1016/J.Molcel.2014.04.004  0.329
2014 Helander S, Montecchio M, Lemak A, Farès C, Almlöf J, Li Y, Yee A, Arrowsmith CH, Dhe-Paganon S, Sunnerhagen M. Basic Tilted Helix Bundle - a new protein fold in human FKBP25/FKBP3 and HectD1. Biochemical and Biophysical Research Communications. 447: 26-31. PMID 24667607 DOI: 10.1016/j.bbrc.2014.03.068  0.378
2014 Arrowsmith C. Structural Genomics of Chromatin Regulators for Biological Discovery & Epigenetic Therapy Acta Crystallographica Section a Foundations and Advances. 70: C33-C33. DOI: 10.1107/S2053273314099665  0.437
2013 Wu H, Zeng H, Dong A, Li F, He H, Senisterra G, Seitova A, Duan S, Brown PJ, Vedadi M, Arrowsmith CH, Schapira M. Structure of the catalytic domain of EZH2 reveals conformational plasticity in cofactor and substrate binding sites and explains oncogenic mutations. Plos One. 8: e83737. PMID 24367611 DOI: 10.1371/journal.pone.0083737  0.324
2013 Lemak A, Yee A, Wu H, Yap D, Zeng H, Dombrovski L, Houliston S, Aparicio S, Arrowsmith CH. Solution NMR structure and histone binding of the PHD domain of human MLL5. Plos One. 8: e77020. PMID 24130829 DOI: 10.1371/journal.pone.0077020  0.339
2013 Rothbart SB, Dickson BM, Ong MS, Krajewski K, Houliston S, Kireev DB, Arrowsmith CH, Strahl BD. Multivalent histone engagement by the linked tandem Tudor and PHD domains of UHRF1 is required for the epigenetic inheritance of DNA methylation. Genes & Development. 27: 1288-98. PMID 23752590 DOI: 10.1101/Gad.220467.113  0.316
2013 James LI, Barsyte-Lovejoy D, Zhong N, Krichevsky L, Korboukh VK, Herold JM, MacNevin CJ, Norris JL, Sagum CA, Tempel W, Marcon E, Guo H, Gao C, Huang XP, Duan S, ... ... Arrowsmith CH, et al. Discovery of a chemical probe for the L3MBTL3 methyllysine reader domain. Nature Chemical Biology. 9: 184-91. PMID 23292653 DOI: 10.1038/Nchembio.1157  0.302
2013 Senisterra G, Wu H, Allali-Hassani A, Wasney GA, Barsyte-Lovejoy D, Dombrovski L, Dong A, Nguyen KT, Smil D, Bolshan Y, Hajian T, He H, Seitova A, Chau I, Li F, ... ... Arrowsmith CH, et al. Small-molecule inhibition of MLL activity by disruption of its interaction with WDR5. The Biochemical Journal. 449: 151-9. PMID 22989411 DOI: 10.1042/Bj20121280  0.31
2012 Rothbart SB, Krajewski K, Nady N, Tempel W, Xue S, Badeaux AI, Barsyte-Lovejoy D, Martinez JY, Bedford MT, Fuchs SM, Arrowsmith CH, Strahl BD. Association of UHRF1 with methylated H3K9 directs the maintenance of DNA methylation. Nature Structural & Molecular Biology. 19: 1155-60. PMID 23022729 DOI: 10.1038/Nsmb.2391  0.716
2012 Nady N, Krichevsky L, Zhong N, Duan S, Tempel W, Amaya MF, Ravichandran M, Arrowsmith CH. Histone recognition by human malignant brain tumor domains. Journal of Molecular Biology. 423: 702-18. PMID 22954662 DOI: 10.1016/J.Jmb.2012.08.022  0.758
2012 Yang Y, Ramelot TA, Cort JR, Garcia M, Yee A, Arrowsmith CH, Kennedy MA. Solution NMR structure of hypothetical protein CV_2116 encoded by a viral prophage element in Chromobacterium violaceum. International Journal of Molecular Sciences. 13: 7354-64. PMID 22837698 DOI: 10.3390/Ijms13067354  0.307
2012 Popovic A, Wu B, Arrowsmith CH, Edwards AM, Davidson AR, Maxwell KL. Structural and biochemical characterization of phage λ FI protein (gpFI) reveals a novel mechanism of DNA packaging chaperone activity. The Journal of Biological Chemistry. 287: 32085-95. PMID 22801427 DOI: 10.1074/jbc.M112.378349  0.393
2012 Xu C, Jin J, Bian C, Lam R, Tian R, Weist R, You L, Nie J, Bochkarev A, Tempel W, Tan CS, Wasney GA, Vedadi M, Gish GD, Arrowsmith CH, et al. Sequence-specific recognition of a PxLPxI/L motif by an ankyrin repeat tumbler lock. Science Signaling. 5: ra39. PMID 22649097 DOI: 10.1126/scisignal.2002979  0.323
2012 Brázda V, Coufal J, Liao JC, Arrowsmith CH. Preferential binding of IFI16 protein to cruciform structure and superhelical DNA. Biochemical and Biophysical Research Communications. 422: 716-20. PMID 22618232 DOI: 10.1016/j.bbrc.2012.05.065  0.592
2012 Arrowsmith CH, Bountra C, Fish PV, Lee K, Schapira M. Epigenetic protein families: A new frontier for drug discovery Nature Reviews Drug Discovery. 11: 384-400. PMID 22498752 DOI: 10.1038/nrd3674  0.308
2012 Rosato A, Aramini JM, Arrowsmith C, Bagaria A, Baker D, Cavalli A, Doreleijers JF, Eletsky A, Giachetti A, Guerry P, Gutmanas A, Güntert P, He Y, Herrmann T, Huang YJ, et al. Blind testing of routine, fully automated determination of protein structures from NMR data. Structure (London, England : 1993). 20: 227-36. PMID 22325772 DOI: 10.1016/J.Str.2012.01.002  0.385
2012 Singer AU, Wu B, Yee A, Houliston S, Xu X, Cui H, Skarina T, Garcia M, Semesi A, Arrowsmith CH, Savchenko A. Structural analysis of HopPmaL reveals the presence of a second adaptor domain common to the HopAB family of Pseudomonas syringae type III effectors. Biochemistry. 51: 1-3. PMID 22191472 DOI: 10.1021/bi2013883  0.312
2012 Lemak A, Yee A, Houliston S, Garcia M, Dhe-Paganon S, Montelione GT, Arrowsmith C. NMR solution structure of the N-terminal domain of human USP28. Northeast structural genomics consortium target HT8470A Journal of Back and Musculoskeletal Rehabilitation. DOI: 10.2210/Pdb2Lva/Pdb  0.388
2011 Hakem A, Bohgaki M, Lemmers B, Tai E, Salmena L, Matysiak-Zablocki E, Jung YS, Karaskova J, Kaustov L, Duan S, Madore J, Boutros P, Sheng Y, Chesi M, Bergsagel PL, ... ... Arrowsmith C, et al. Role of Pirh2 in mediating the regulation of p53 and c-Myc. Plos Genetics. 7: e1002360. PMID 22125490 DOI: 10.1371/Journal.Pgen.1002360  0.315
2011 Lemak A, Yee A, Bezsonova I, Dhe-Paganon S, Arrowsmith CH. Zn-binding AZUL domain of human ubiquitin protein ligase Ube3A. Journal of Biomolecular Nmr. 51: 185-90. PMID 21947926 DOI: 10.1007/s10858-011-9552-y  0.322
2011 Brázda V, Laister RC, Jagelská EB, Arrowsmith C. Cruciform structures are a common DNA feature important for regulating biological processes. Bmc Molecular Biology. 12: 33. PMID 21816114 DOI: 10.1186/1471-2199-12-33  0.478
2011 Nady N, Lemak A, Walker JR, Avvakumov GV, Kareta MS, Achour M, Xue S, Duan S, Allali-Hassani A, Zuo X, Wang YX, Bronner C, Chédin F, Arrowsmith CH, Dhe-Paganon S. Recognition of multivalent histone states associated with heterochromatin by UHRF1 protein. The Journal of Biological Chemistry. 286: 24300-11. PMID 21489993 DOI: 10.1074/Jbc.M111.234104  0.753
2011 Herold JM, Wigle TJ, Norris JL, Lam R, Korboukh VK, Gao C, Ingerman LA, Kireev DB, Senisterra G, Vedadi M, Tripathy A, Brown PJ, Arrowsmith CH, Jin J, Janzen WP, et al. Small-molecule ligands of methyl-lysine binding proteins. Journal of Medicinal Chemistry. 54: 2504-11. PMID 21417280 DOI: 10.1021/jm200045v  0.352
2011 Liao JC, Lam R, Brazda V, Duan S, Ravichandran M, Ma J, Xiao T, Tempel W, Zuo X, Wang YX, Chirgadze NY, Arrowsmith CH. Interferon-inducible protein 16: insight into the interaction with tumor suppressor p53. Structure (London, England : 1993). 19: 418-29. PMID 21397192 DOI: 10.1016/j.str.2010.12.015  0.611
2011 Kaustov L, Ouyang H, Amaya M, Lemak A, Nady N, Duan S, Wasney GA, Li Z, Vedadi M, Schapira M, Min J, Arrowsmith CH. Recognition and specificity determinants of the human cbx chromodomains. The Journal of Biological Chemistry. 286: 521-9. PMID 21047797 DOI: 10.1074/Jbc.M110.191411  0.748
2011 Lemak A, Srisailam S, Lukin J, Yee A, Montecchio M, Semesi A, Arrowsmith C. Solution NMR structure of holo acyl carrier protein NE2163 from nitrosomonas europaea. Northeast structural genomics consortium target NET1 Journal of Back and Musculoskeletal Rehabilitation. DOI: 10.2210/Pdb2Lki/Pdb  0.384
2011 Lemak A, Yee A, Houliston S, Garcia M, Chitayat S, Dhe-Paganon S, Montelione GT, Arrowsmith C. Solution NMR structure of N-terminal domain of human E3 ubiquitin-protein ligase HECW2. Northeast structural genomics consortium (NESG) target ht6306a Journal of Back and Musculoskeletal Rehabilitation. DOI: 10.2210/Pdb2Lfe/Pdb  0.42
2011 Lemak A, Yee A, Houliston S, Garcia M, Daniels C, Savchenko A, Arrowsmith C, Montelione GT. Solution NMR structure of N-terminal domain of Salmonella effector protein PipB2. Northeast structural genomics consortium (NESG) target stt318a Journal of Back and Musculoskeletal Rehabilitation. DOI: 10.2210/Pdb2Lez/Pdb  0.425
2010 Koulov AV, LaPointe P, Lu B, Razvi A, Coppinger J, Dong MQ, Matteson J, Laister R, Arrowsmith C, Yates JR, Balch WE. Biological and structural basis for Aha1 regulation of Hsp90 ATPase activity in maintaining proteostasis in the human disease cystic fibrosis. Molecular Biology of the Cell. 21: 871-84. PMID 20089831 DOI: 10.1091/Mbc.E09-12-1017  0.354
2010 Wu H, Min J, Lunin VV, Antoshenko T, Dombrovski L, Zeng H, Allali-Hassani A, Campagna-Slater V, Vedadi M, Arrowsmith CH, Plotnikov AN, Schapira M. Structural biology of human H3K9 methyltransferases. Plos One. 5: e8570. PMID 20084102 DOI: 10.1371/journal.pone.0008570  0.313
2010 Wigle TJ, Herold JM, Senisterra GA, Vedadi M, Kireev DB, Arrowsmith CH, Frye SV, Janzen WP. Screening for inhibitors of low-affinity epigenetic peptide-protein interactions: an AlphaScreen-based assay for antagonists of methyl-lysine binding proteins. Journal of Biomolecular Screening. 15: 62-71. PMID 20008125 DOI: 10.1177/1087057109352902  0.304
2010 Bezsonova I, Neculai D, Korzhnev D, Weigelt J, Bountra C, Edwards A, Arrowsmith C, Dhe-Paganon S. NMR structure of the HLTF HIRAN domain Journal of Back and Musculoskeletal Rehabilitation. DOI: 10.2210/Pdb2L1I/Pdb  0.385
2010 Kaustov L, Lemak A, Fares C, Gutmanas A, Quang H, Loppnau P, Min J, Edwards A, Arrowsmith C. Solution NMR structure of the Cbx3 in complex with H3K9me3 peptide Journal of Back and Musculoskeletal Rehabilitation. DOI: 10.2210/Pdb2L11/Pdb  0.321
2010 Bezsonova I, Lemak A, Avvakumov G, Xue S, Dhe-Paganon S, Montelione GT, Arrowsmith C. Solution NMR structure of human ubiquitin specific protease Usp7 UBL domain (residues 537-664). NESG target hr4395c/ SGC-Toronto Journal of Back and Musculoskeletal Rehabilitation. DOI: 10.2210/Pdb2Kvr/Pdb  0.399
2010 Gutmanas A, Fares C, Yee A, Lemak A, Semesi A, Arrowsmith C. Solution NMR structure of uncharacterized protein CV0863 from Chromobacterium violaceum. NESG target CvT3. OCSP target CV0863. Journal of Back and Musculoskeletal Rehabilitation. DOI: 10.13018/Bmr16790  0.354
2010 Laister R, Wu B, Lemak A, Arrowsmith C. Solution NMR structure of the Mus81 N-terminal HhH. Northeast Structural Genomics Consortium target MmT1A Journal of Back and Musculoskeletal Rehabilitation. DOI: 10.13018/Bmr16549  0.354
2009 Bezsonova I, Walker JR, Bacik JP, Duan S, Dhe-Paganon S, Arrowsmith CH. Ring1B contains a ubiquitin-like docking module for interaction with Cbx proteins Biochemistry. 48: 10542-10548. PMID 19791798 DOI: 10.1021/bi901131u  0.36
2009 Brázda V, Jagelska EB, Liao JC, Arrowsmith CH. The central region of BRCA1 binds preferentially to supercoiled DNA. Journal of Biomolecular Structure & Dynamics. 27: 97-104. PMID 19492866 DOI: 10.1080/07391102.2009.10507299  0.543
2009 Montelione GT, Arrowsmith C, Girvin ME, Kennedy MA, Markley JL, Powers R, Prestegard JH, Szyperski T. Unique opportunities for NMR methods in structural genomics. Journal of Structural and Functional Genomics. 10: 101-6. PMID 19288278 DOI: 10.1007/S10969-009-9064-0  0.37
2009 Guo Y, Nady N, Qi C, Allali-Hassani A, Zhu H, Pan P, Adams-Cioaba MA, Amaya MF, Dong A, Vedadi M, Schapira M, Read RJ, Arrowsmith CH, Min J. Methylation-state-specific recognition of histones by the MBT repeat protein L3MBTL2. Nucleic Acids Research. 37: 2204-10. PMID 19233876 DOI: 10.1093/Nar/Gkp086  0.752
2009 Lemak A, Yee A, Lee H, Semesi A, Prestegard J, Montelione GT, Arrowsmith C. Solution structure of protein CV0426 from Chromobacterium violaceum, Northeast structural genomics consortium (NESG) target CVT2 Journal of Back and Musculoskeletal Rehabilitation. DOI: 10.2210/Pdb2Kp6/Pdb  0.376
2009 Lemak A, Yee A, Wu B, Karra M, Ramelot T, Fares C, Semesi A, Kennedy M, Montelione GT, Arrowsmith C. Solution NMR structure of protein AF2094 from Archaeoglobus fulgidus. Northeast Structural Genomics Consotium (NESG) target GT2 Journal of Back and Musculoskeletal Rehabilitation. DOI: 10.2210/Pdb2Kk4/Pdb  0.382
2009 Wu B, Yee A, Fares C, Lemak A, Semest A, Arrowsmith C. Solution structure of DnaK suppressor protein from Agrobacterium tumefaciens C58. Northeast Structural Genomics Consortium target AtT12/Ontario Center for Structural Proteomics Target atc0888 Journal of Back and Musculoskeletal Rehabilitation. DOI: 10.13018/Bmr16594  0.377
2009 Gutmanas A, Yee A, Lemak A, Fares C, Semesi A, Arrowsmith C. Solution structure of protein Atu0922 from A. tumefaciens. Northeast Structural Genomics Consortium target AtT13. Ontario Center for Structural Proteomics target ATC0905. Journal of Back and Musculoskeletal Rehabilitation. DOI: 10.13018/Bmr16476  0.372
2009 Wu B, Yee A, Fares C, Lemak A, Semest A, Claude M, Singer A, Edwards A, Savchenko A, Arrowsmith C. Solution Structure of C-terminal domain of oxidized NleG2-3 (residue 90-191) from Pathogenic E. coli O157:H7. Northeast Structural Genomics Consortium and Midwest Center for Structural Genomics target ET109A Journal of Back and Musculoskeletal Rehabilitation. DOI: 10.13018/Bmr16374  0.362
2009 Eletsky A, Wu Y, Yee A, Fares C, Lee H, Prestegard J, Arrowsmith C, Szyperski T. Solution NMR structure of tungsten formylmethanofuran dehydrogenase subunit D from Archaeoglobus fulgidus, Northeast Structural Genomics Consortium target AtT7 Journal of Back and Musculoskeletal Rehabilitation. DOI: 10.13018/Bmr16267  0.334
2009 Lemak A, Gutmanas A, Fares C, Quyang H, Dhe-Paganon S, Montelione G, Arrowsmith C. Solution NMR structure of protein HS00059 from Homo Sapiens. Northeast Structural Genomics Consortium (NESG) target HT98A. Journal of Back and Musculoskeletal Rehabilitation. DOI: 10.13018/Bmr16155  0.386
2009 Buchko G, Yee A, Semesi A, Hui R, Arrowsmith C. Solution structure of PFE0790c, a putative bolA-like protein from the protozoan parasite Plasmodium falciparum: A Structural Genomics Center for Infectious Disease (SSGCID) community request. Journal of Back and Musculoskeletal Rehabilitation. DOI: 10.13018/Bmr16118  0.341
2009 Wu B, Yee A, Lemak A, Cort J, Semest A, Kenney M, Arrowsmith C. Solution NMR Structure of protein hp1203 from Helicobacter pylori 26695 Journal of Back and Musculoskeletal Rehabilitation. DOI: 10.13018/Bmr15661  0.355
2009 Wu B, Yee A, Lemak A, Cort J, Bansal S, Semest A, Guido V, Kennedy M, Prestegard J, Arrowsmith C. A novel domain-swapped solution NMR structure of protein RPA2121 from Rhodopseudomonas palustris Journal of Back and Musculoskeletal Rehabilitation. DOI: 10.13018/Bmr15324  0.429
2009 Cerchietti LC, Ghetu A, Zhu X, Silva GD, Zhong S, Matthews M, Polo J, Farès C, Arrowsmith C, Bunting K, Coop A, MacKerell A, Privè G, Melnick A. Abstract B236: A small molecule disrupts the BCL6 transcriptional repressor complex and kills lymphoma cells in vitro and in vivo Molecular Cancer Therapeutics. 8. DOI: 10.1158/1535-7163.Targ-09-B236  0.332
2008 Sheng Y, Laister RC, Lemak A, Wu B, Tai E, Duan S, Lukin J, Sunnerhagen M, Srisailam S, Karra M, Benchimol S, Arrowsmith CH. Molecular basis of Pirh2-mediated p53 ubiquitylation. Nature Structural & Molecular Biology. 15: 1334-42. PMID 19043414 DOI: 10.1038/Nsmb.1521  0.301
2008 Nady N, Min J, Kareta MS, Chédin F, Arrowsmith CH. A SPOT on the chromatin landscape? Histone peptide arrays as a tool for epigenetic research. Trends in Biochemical Sciences. 33: 305-13. PMID 18538573 DOI: 10.1016/J.Tibs.2008.04.014  0.717
2008 Schuetz A, Min J, Allali-Hassani A, Schapira M, Shuen M, Loppnau P, Mazitschek R, Kwiatkowski NP, Lewis TA, Maglathin RL, McLean TH, Bochkarev A, Plotnikov AN, Vedadi M, Arrowsmith CH. Human HDAC7 harbors a class IIa histone deacetylase-specific zinc binding motif and cryptic deacetylase activity. The Journal of Biological Chemistry. 283: 11355-63. PMID 18285338 DOI: 10.1074/Jbc.M707362200  0.3
2008 Wu B, Yee A, Huang YJ, Ramelot TA, Cort JR, Semesi A, Jung JW, Lee W, Montelione GT, Kennedy MA, Arrowsmith CH. The solution structure of ribosomal protein S17E from Methanobacterium thermoautotrophicum: a structural homolog of the FF domain. Protein Science : a Publication of the Protein Society. 17: 583-8. PMID 18218711 DOI: 10.1110/Ps.073272208  0.344
2008 Ai X, Semesi A, Yee A, Arrowsmith CH, Choy WY, Li SS. The hypothetical protein Atu4866 from Agrobacterium tumefaciens adopts a streptavidin-like fold. Protein Science : a Publication of the Protein Society. 17: 154-8. PMID 18042676 DOI: 10.1110/ps.073167408  0.333
2008 Lemak A, Srisailam S, Yee A, Bansal S, Semesi A, Prestegard J, Montelione GT, Arrowsmith C. Solution NMR structure of protein ATU0232 from AGROBACTERIUM TUMEFACIENS. Northeast Structural Genomics Consortium (NESG) target AtT3. Ontario Center for Structural Proteomics target ATC0223. Journal of Back and Musculoskeletal Rehabilitation. DOI: 10.2210/Pdb2K7I/Pdb  0.381
2008 Wu Y, Singarapu K, Semesi A, Yee A, Bansal S, Prestegard J, Arrowsmith C, Szyperski T, Montelione GT. Solution structure of protein yiiF from Shigella flexneri serotype 5b (strain 8401) . Northeast Structural Genomics Consortium target sft1 Journal of Back and Musculoskeletal Rehabilitation. DOI: 10.2210/Pdb2K5J/Pdb  0.341
2008 Wu Y, Singarapu K, Semesi A, Sukumaran D, Yee A, Garcia M, Arrowsmith C, Szyperski T, Montelione GT. Solution NMR structure of protein encoded by MTH693 from Methanobacterium thermoautotrophicum: Northeast Structural Genomics Consortium target tt824a Journal of Back and Musculoskeletal Rehabilitation. DOI: 10.2210/Pdb2K5H/Pdb  0.391
2008 Lemak A, Sheng Y, Karra M, Srisailam S, Laister R, Duan S, Arrowsmith C. solution struture of human C-terminal domain of pirh2/Northeast Structural Genomics Consortium (NESG) target HT2C Journal of Back and Musculoskeletal Rehabilitation. DOI: 10.13018/Bmr15701  0.36
2008 Ramelot T, Cort J, Semesi A, Garcia M, Yee A, Arrowsmith C, Kennedy M. NMR solution structure of TnpE protein from Shigella flexneri.Northeast Structural Genomics Target SfR125. Journal of Back and Musculoskeletal Rehabilitation. DOI: 10.13018/Bmr11017  0.387
2008 Dong A, Xu X, Bochkarev A, Savchenko A, Joachimiak A, Arrowsmith C, Edwards A. In situproteolysis for protein crystallization and structure determination Acta Crystallographica Section a Foundations of Crystallography. 64: C580-C580. DOI: 10.1107/S010876730808135X  0.338
2008 Min J, Allali-Hassani A, Nady N, Qi C, Ouyang H, Liu Y, MacKenzie F, Vedadi M, Arrowsmith CH. Erratum: L3MBTL1 recognition of mono- and dimethylated histones Nature Structural & Molecular Biology. 15: 114-114. DOI: 10.1038/Nsmb0108-114  0.703
2007 Min J, Allali-Hassani A, Nady N, Qi C, Ouyang H, Liu Y, MacKenzie F, Vedadi M, Arrowsmith CH. L3MBTL1 recognition of mono- and dimethylated histones. Nature Structural & Molecular Biology. 14: 1229-30. PMID 18026117 DOI: 10.1038/Nsmb1340  0.722
2007 Dong A, Xu X, Edwards AM, Chang C, Chruszcz M, Cuff M, Cymborowski M, Di Leo R, Egorova O, Evdokimova E, Filippova E, Gu J, Guthrie J, ... ... Arrowsmith C, et al. In situ proteolysis for protein crystallization and structure determination. Nature Methods. 4: 1019-21. PMID 17982461 DOI: 10.1038/Nmeth1118  0.362
2007 Wang X, Srisailam S, Yee AA, Lemak A, Arrowsmith C, Prestegard JH, Tian F. Domain-domain motions in proteins from time-modulated pseudocontact shifts. Journal of Biomolecular Nmr. 39: 53-61. PMID 17657568 DOI: 10.1007/S10858-007-9174-6  0.364
2007 Monleón D, Yee A, Arrowsmith C, Celda B. NMR structure of hypothetical protein TA0938 from Thermoplasma acidophilum. Proteins. 67: 1185-8. PMID 17377985 DOI: 10.1002/Prot.21143  0.406
2007 Kaustov L, Lukin J, Lemak A, Duan S, Ho M, Doherty R, Penn LZ, Arrowsmith CH. The conserved CPH domains of Cul7 and PARC are protein-protein interaction modules that bind the tetramerization domain of p53. The Journal of Biological Chemistry. 282: 11300-7. PMID 17298945 DOI: 10.1074/Jbc.M611297200  0.312
2007 Najmanovich RJ, Allali-Hassani A, Morris RJ, Dombrovsky L, Pan PW, Vedadi M, Plotnikov AN, Edwards A, Arrowsmith C, Thornton JM. Analysis of binding site similarity, small-molecule similarity and experimental binding profiles in the human cytosolic sulfotransferase family. Bioinformatics (Oxford, England). 23: e104-9. PMID 17237076 DOI: 10.1093/Bioinformatics/Btl292  0.336
2007 Vedadi M, Lew J, Artz J, Amani M, Zhao Y, Dong A, Wasney GA, Gao M, Hills T, Brokx S, Qiu W, Sharma S, Diassiti A, Alam Z, Melone M, ... ... Arrowsmith C, et al. Genome-scale protein expression and structural biology of Plasmodium falciparum and related Apicomplexan organisms. Molecular and Biochemical Parasitology. 151: 100-10. PMID 17125854 DOI: 10.1016/J.Molbiopara.2006.10.011  0.344
2007 Ramelot TA, Yee A, Cort JR, Semesi A, Arrowsmith CH, Kennedy MA. NMR structure and binding studies confirm that PA4608 from Pseudomonas aeruginosa is a PilZ domain and a c-di-GMP binding protein. Proteins. 66: 266-71. PMID 17096419 DOI: 10.1002/Prot.21199  0.325
2007 Ignatchenko A, Gutmanas A, Lemak A, Yee A, Karra M, Srisailam S, Arrowsmith C. Solution Structure of protein RPA3401, Northeast Structural Genomics Consortium Target RpT7, Ontario Center for Structural Proteomics Target RP3384 Journal of Back and Musculoskeletal Rehabilitation. DOI: 10.2210/Pdb2Jtv/Pdb  0.374
2007 Singarapu KK, Wu Y, Yee A, Semesi A, Arrowsmith C, Szyperski T. NMR Structure of 50S Ribosomal Protein L14e from Sulfolobus Solfataricus: Northeast Structural Genomics Consortium Target SSR105 Journal of Back and Musculoskeletal Rehabilitation. DOI: 10.2210/Pdb2Joy/Pdb  0.386
2007 Ramelot T, Cort J, Yee A, Semesi A, Johnathan L, Arrowsmith C, Kennedy M. NMR structure of E.coli YfgJ protein modelled with two Zn+2 bound. Northeast Structural Genomics Consortium Target ER317. Journal of Back and Musculoskeletal Rehabilitation. DOI: 10.2210/Pdb2Jne/Pdb  0.363
2007 Higman VA, Leidert M, Bray J, Elkins J, Soundararajan M, Doyle DA, Gileadi C, Phillips C, Schoch G, Yang X, Brockmann C, Schmieder P, Diehl A, Sundstrom M, Arrowsmith C, et al. Solution structure of the RGS domain of human RGS14 Journal of Back and Musculoskeletal Rehabilitation. DOI: 10.2210/Pdb2Jm5/Pdb  0.352
2007 Doherty R, Dhe-Paganon S, Fares C, Lemak A, Butler C, Srisailam S, Karra M, Yee A, Edwards A, Weigelt J, Arrowsmith C. Ubiquitin-like domain of NFATC2IP. Northeast Structural Genomics Consortium Target hr5627. Journal of Back and Musculoskeletal Rehabilitation. DOI: 10.13018/Bmr15576  0.358
2007 Cort J, Yee A, Arrowsmith C, Kennedy M. Chemical Shift Assignments for protein NE0084 from Nitrosomonas europea: Northeast Structural Genomics Target NeT6 Journal of Back and Musculoskeletal Rehabilitation. DOI: 10.13018/Bmr15347  0.363
2006 Vedadi M, Niesen FH, Allali-Hassani A, Fedorov OY, Finerty PJ, Wasney GA, Yeung R, Arrowsmith C, Ball LJ, Berglund H, Hui R, Marsden BD, Nordlund P, Sundstrom M, Weigelt J, et al. Chemical screening methods to identify ligands that promote protein stability, protein crystallization, and structure determination. Proceedings of the National Academy of Sciences of the United States of America. 103: 15835-40. PMID 17035505 DOI: 10.1073/Pnas.0605224103  0.371
2006 Schuetz A, Allali-Hassani A, Martín F, Loppnau P, Vedadi M, Bochkarev A, Plotnikov AN, Arrowsmith CH, Min J. Structural basis for molecular recognition and presentation of histone H3 by WDR5. The Embo Journal. 25: 4245-52. PMID 16946699 DOI: 10.1038/sj.emboj.7601316  0.301
2006 Monleón D, Nunes S, Esteve V, Yee A, Arrowsmith C, Celda B. Resonance assignments for the hypothetical protein TA0938 from Thermoplasma acidophilum. Journal of Biomolecular Nmr. 36: 36. PMID 16703419 DOI: 10.1007/S10858-006-5968-1  0.31
2006 Kaustov L, Yi GS, Ayed A, Bochkareva E, Bochkarev A, Arrowsmith CH. p53 transcriptional activation domain: A molecular chameleon? Cell Cycle. 5: 489-494. PMID 16481746  0.365
2006 Kim B, Jung J, Hong E, Yee A, Arrowsmith CH, Lee W. NMR structure of the conserved novel-fold protein TA0743 from Thermoplasma acidophilum. Proteins. 62: 819-21. PMID 16374782 DOI: 10.1002/prot.20832  0.312
2006 Eletsky A, Atreya H, Liu G, Sukumaran D, Garcia M, Yee A, Arrowsmith C, Szyperski T. 1H, 13C, and 15N Chemical Shift Assignments for Pseudomonas aeruginosa Hypothetical Protein RPA1041: Northeast Structural Genomics Consortium target Pat90 Journal of Back and Musculoskeletal Rehabilitation. DOI: 10.13018/Bmr7191  0.361
2006 Higman V, Leidert M, Elkins J, Soundararajan M, Brockmann C, Schmieder P, Sundstrom M, Arrowsmith C, Weigelt J, Edwards A, Diehl A, Oschkinat H, Ball L. NMR Assignment of human RGS18 (regulator of G-protein signalling) Journal of Back and Musculoskeletal Rehabilitation. DOI: 10.13018/Bmr7106  0.308
2005 Bochkareva E, Kaustov L, Ayed A, Yi GS, Lu Y, Pineda-Lucena A, Liao JC, Okorokov AL, Milner J, Arrowsmith CH, Bochkarev A. Single-stranded DNA mimicry in the p53 transactivation domain interaction with replication protein A. Proceedings of the National Academy of Sciences of the United States of America. 102: 15412-7. PMID 16234232 DOI: 10.1073/pnas.0504614102  0.621
2005 Grishaev A, Steren CA, Wu B, Pineda-Lucena A, Arrowsmith C, Llinás M. ABACUS, a direct method for protein NMR structure computation via assembly of fragments. Proteins. 61: 36-43. PMID 16080153 DOI: 10.1002/Prot.20457  0.355
2005 Saridakis V, Sheng Y, Sarkari F, Holowaty MN, Shire K, Nguyen T, Zhang RG, Liao J, Lee W, Edwards AM, Arrowsmith CH, Frappier L. Structure of the p53 binding domain of HAUSP/USP7 bound to Epstein-Barr nuclear antigen 1 implications for EBV-mediated immortalization. Molecular Cell. 18: 25-36. PMID 15808506 DOI: 10.1016/J.Molcel.2005.02.029  0.581
2005 Huang YJ, Moseley HN, Baran MC, Arrowsmith C, Powers R, Tejero R, Szyperski T, Montelione GT. An integrated platform for automated analysis of protein NMR structures. Methods in Enzymology. 394: 111-41. PMID 15808219 DOI: 10.1016/S0076-6879(05)94005-6  0.37
2005 Savchenko A, Krogan N, Cort JR, Evdokimova E, Lew JM, Yee AA, Sánchez-Pulido L, Andrade MA, Bochkarev A, Watson JD, Kennedy MA, Greenblatt J, Hughes T, Arrowsmith CH, Rommens JM, et al. The Shwachman-Bodian-Diamond syndrome protein family is involved in RNA metabolism. The Journal of Biological Chemistry. 280: 19213-20. PMID 15701634 DOI: 10.1074/Jbc.M414421200  0.325
2005 Gaspar JA, Liu C, Vassall KA, Meglei G, Stephen R, Stathopulos PB, Pineda-Lucena A, Wu B, Yee A, Arrowsmith CH, Meiering EM. A novel member of the YchN-like fold: solution structure of the hypothetical protein Tm0979 from Thermotoga maritima. Protein Science : a Publication of the Protein Society. 14: 216-23. PMID 15608123 DOI: 10.1110/ps.041068605  0.301
2005 Mark WY, Liao JC, Lu Y, Ayed A, Laister R, Szymczyna B, Chakrabartty A, Arrowsmith CH. Characterization of segments from the central region of BRCA1: an intrinsically disordered scaffold for multiple protein-protein and protein-DNA interactions? Journal of Molecular Biology. 345: 275-87. PMID 15571721 DOI: 10.1016/J.Jmb.2004.10.045  0.782
2005 Ramelot T, Yee A, Arrowsmith C, Kennedy M. 1H, 13C, and 15N Chemical Shift Assignments for Psuedomonas Aeruginosa protein PA4608 Journal of Back and Musculoskeletal Rehabilitation. DOI: 10.13018/Bmr6514  0.304
2005 Ramelot T, Cort J, Yee A, Guido V, Lukin J, Arrowsmith C, Kennedy M. NMR structure of the E.coli protein NirD, Northeast Structural Genomics target ET100 Journal of Back and Musculoskeletal Rehabilitation. DOI: 10.13018/Bmr15139  0.362
2004 Gutiérrez P, Osborne MJ, Siddiqui N, Trempe JF, Arrowsmith C, Gehring K. Structure of the archaeal translation initiation factor aIF2 beta from Methanobacterium thermoautotrophicum: implications for translation initiation. Protein Science : a Publication of the Protein Society. 13: 659-67. PMID 14978306 DOI: 10.1110/Ps.03506604  0.325
2004 Monleón D, Yee A, Liu CS, Arrowsmith C, Celda B. Solution structure of hypothetical protein TA1414 from Thermoplasma acidophilum. Journal of Biomolecular Nmr. 28: 81-4. PMID 14739641 DOI: 10.1023/B:Jnmr.0000012862.33577.74  0.367
2004 Wu B, Yee A, Ramelot T, Cort J, Kennedy M, Arrowsmith C. Northeast Structural Genomics Consortium Target TT802 Ontario Center for Structural Proteomics Target Mth0803 assignment of ribosomal protein S17E Journal of Back and Musculoskeletal Rehabilitation. DOI: 10.13018/Bmr6028  0.36
2003 Wu B, Yee A, Pineda-Lucena A, Semesi A, Ramelot TA, Cort JR, Jung JW, Edwards A, Lee W, Kennedy M, Arrowsmith CH. Solution structure of ribosomal protein S28E from Methanobacterium thermoautotrophicum. Protein Science : a Publication of the Protein Society. 12: 2831-7. PMID 14627743 DOI: 10.1110/Ps.03358203  0.315
2003 Abraham J, Lemmers B, Hande MP, Moynahan ME, Chahwan C, Ciccia A, Essers J, Hanada K, Chahwan R, Khaw AK, McPherson P, Shehabeldin A, Laister R, Arrowsmith C, Kanaar R, et al. Eme1 is involved in DNA damage processing and maintenance of genomic stability in mammalian cells. The Embo Journal. 22: 6137-47. PMID 14609959 DOI: 10.1093/Emboj/Cdg580  0.356
2003 Holowaty MN, Sheng Y, Nguyen T, Arrowsmith C, Frappier L. Protein interaction domains of the ubiquitin-specific protease, USP7/HAUSP. The Journal of Biological Chemistry. 278: 47753-61. PMID 14506283 DOI: 10.1074/Jbc.M307200200  0.43
2003 Daughdrill GW, Buchko GW, Botuyan MV, Arrowsmith C, Wold MS, Kennedy MA, Lowry DF. Chemical shift changes provide evidence for overlapping single-stranded DNA- and XPA-binding sites on the 70 kDa subunit of human replication protein A. Nucleic Acids Research. 31: 4176-83. PMID 12853635 DOI: 10.1093/Nar/Gkg451  0.426
2003 Pineda-Lucena A, Liao JC, Cort JR, Yee A, Kennedy MA, Edwards AM, Arrowsmith CH. A novel member of the split betaalphabeta fold: Solution structure of the hypothetical protein YML108W from Saccharomyces cerevisiae. Protein Science : a Publication of the Protein Society. 12: 1136-40. PMID 12717036 DOI: 10.1110/Ps.0240903  0.545
2003 Szymczyna BR, Bowman J, McCracken S, Pineda-Lucena A, Lu Y, Cox B, Lambermon M, Graveley BR, Arrowsmith CH, Blencowe BJ. Structure and function of the PWI motif: a novel nucleic acid-binding domain that facilitates pre-mRNA processing. Genes & Development. 17: 461-75. PMID 12600940 DOI: 10.1101/Gad.1060403  0.739
2003 Yang Z, Savchenko A, Yakunin A, Zhang R, Edwards A, Arrowsmith C, Tong L. Aspartate dehydrogenase, a novel enzyme identified from structural and functional studies of TM1643. The Journal of Biological Chemistry. 278: 8804-8. PMID 12496312 DOI: 10.1074/Jbc.M211892200  0.368
2003 Zarembinski TI, Kim Y, Peterson K, Christendat D, Dharamsi A, Arrowsmith CH, Edwards AM, Joachimiak A. Deep trefoil knot implicated in RNA binding found in an archaebacterial protein. Proteins. 50: 177-83. PMID 12486711 DOI: 10.1002/Prot.10311  0.324
2003 Blanco F, Campos-Olivas R, Yee A, Arrowsmith C, Rico M. 1H, 13C, and 15N assignment of mth677 protein from Methanobacterium Thermoautotrophicum Journal of Back and Musculoskeletal Rehabilitation. DOI: 10.13018/Bmr5704  0.304
2003 Cort J, Yee A, Arrowsmith C, Kennedy M. Solution Structure of the Product of the S. Cerevisiae YHR087W Gene, Northeast Structural Genomics Consortium target YTYst425 Journal of Back and Musculoskeletal Rehabilitation. DOI: 10.13018/Bmr5695  0.322
2002 Ramelot TA, Cort JR, Yee AA, Semesi A, Edwards AM, Arrowsmith CH, Kennedy MA. NMR structure of the Escherichia coli protein YacG: a novel sequence motif in the zinc-finger family of proteins. Proteins. 49: 289-93. PMID 12211008 DOI: 10.1002/Prot.10214  0.324
2002 Maxwell KL, Yee AA, Arrowsmith CH, Gold M, Davidson AR. The solution structure of the bacteriophage lambda head-tail joining protein, gpFII. Journal of Molecular Biology. 318: 1395-404. PMID 12083526 DOI: 10.1016/S0022-2836(02)00276-0  0.331
2002 Gutiérrez P, Coillet-Matillon S, Arrowsmith C, Gehring K. Zinc is required for structural stability of the C-terminus of archaeal translation initiation factor aIF2β Febs Letters. 517: 155-158. PMID 12062427 DOI: 10.1016/S0014-5793(02)02610-8  0.324
2002 Pineda-Lucena A, Liao J, Wu B, Yee A, Cort JR, Kennedy MA, Edwards AM, Arrowsmith CH. NMR structure of the hypothetical protein encoded by the YjbJ gene from Escherichia coli. Proteins. 47: 572-4. PMID 12001238 DOI: 10.1002/Prot.10120  0.577
2002 Szymczyna BR, Pineda-Lucena A, Mills JL, Szyperski T, Arrowsmith CH. 1H, 13C, and 15N resonance assignments and secondary structure of the PWI domain from SRm160 using reduced dimensionality NMR. Journal of Biomolecular Nmr. 22: 299-300. PMID 11991360 DOI: 10.1023/A:1014904502424  0.726
2002 Bhattacharyya S, Habibi-Nazhad B, Amegbey G, Slupsky CM, Yee A, Arrowsmith C, Wishart DS. Identification of a novel archaebacterial thioredoxin: Determination of function through structure Biochemistry. 41: 4760-4770. PMID 11939770 DOI: 10.1021/Bi0115176  0.438
2002 Zhang RG, Kim Y, Skarina T, Beasley S, Laskowski R, Arrowsmith C, Edwards A, Joachimiak A, Savchenko A. Crystal structure of Thermotoga maritima 0065, a member of the IclR transcriptional factor family. The Journal of Biological Chemistry. 277: 19183-90. PMID 11877432 DOI: 10.1074/Jbc.M112171200  0.421
2002 Yee A, Chang X, Pineda-Lucena A, Wu B, Semesi A, Le B, Ramelot T, Lee GM, Bhattacharyya S, Gutierrez P, Denisov A, Lee CH, Cort JR, Kozlov G, Liao J, ... ... Arrowsmith CH, et al. An NMR approach to structural proteomics. Proceedings of the National Academy of Sciences of the United States of America. 99: 1825-30. PMID 11854485 DOI: 10.1073/Pnas.042684599  0.564
2002 Korolev S, Ikeguchi Y, Skarina T, Beasley S, Arrowsmith C, Edwards A, Joachimiak A, Pegg AE, Savchenko A. The crystal structure of spermidine synthase with a multisubstrate adduct inhibitor. Nature Structural Biology. 9: 27-31. PMID 11731804 DOI: 10.1038/Nsb737  0.399
2002 Wu B, Yee A, Arrowsmith C. Assignment for ribosomal protein S28E Journal of Back and Musculoskeletal Rehabilitation. DOI: 10.13018/Bmr5620  0.332
2002 Ramelot T, Cort J, Yee A, Furong L, Goshe M, Edwards A, Smith R, Arrowsmith C, Dever T, Kennedy M. 1H, 15N, 13C NMR Assignments of M156R Protein from myxoma virus, NESG target OP2 Journal of Back and Musculoskeletal Rehabilitation. DOI: 10.13018/Bmr5077  0.31
2001 Daughdrill GW, Ackerman J, Isern NG, Botuyan MV, Arrowsmith C, Wold MS, Lowry DF. The weak interdomain coupling observed in the 70 kDa subunit of human replication protein A is unaffected by ssDNA binding. Nucleic Acids Research. 29: 3270-6. PMID 11470885 DOI: 10.1093/Nar/29.15.3270  0.329
2001 Maxwell KL, Yee AA, Booth V, Arrowsmith CH, Gold M, Davidson AR. The solution structure of bacteriophage lambda protein W, a small morphogenetic protein possessing a novel fold. Journal of Molecular Biology. 308: 9-14. PMID 11302702 DOI: 10.1006/Jmbi.2001.4582  0.672
2001 Davison TS, Nie X, Ma W, Lin Y, Kay C, Benchimol S, Arrowsmith CH. Structure and functionality of a designed p53 dimer. Journal of Molecular Biology. 307: 605-17. PMID 11254385 DOI: 10.1006/Jmbi.2001.4450  0.736
2001 Yee A, Chang X, Pineda-Lucena A, Wu B, Semesi A, Le B, Ramelot T, Lee G, Bhattacharyya S, Gutierrez P, Denisov A, Lee C, Cort J, Kozlov G, Liao J, ... ... Arrowsmith C, et al. Solution structure of hemolysin expression modulating protein Hha Journal of Back and Musculoskeletal Rehabilitation. DOI: 10.13018/Bmr5166  0.348
2000 Cort JR, Yee A, Edwards AM, Arrowsmith CH, Kennedy MA. NMR structure determination and structure-based functional characterization of conserved hypothetical protein MTH1175 from Methanobacterium thermoautotrophicum. Journal of Structural and Functional Genomics. 1: 15-25. PMID 12836677 DOI: 10.1023/A:1011348803324  0.323
2000 Mulder FAA, Ayed A, Yang D, Arrowsmith CH, Kay LE. Assignment of 1H(N), 15N, 13C(α), 13CO and 13C(β) resonances in a 67 kDa p53 dimer using 4D-TROSY NMR spectroscopy Journal of Biomolecular Nmr. 18: 173-176. PMID 11101222 DOI: 10.1023/A:1008317825976  0.313
2000 Christendat D, Yee A, Dharamsi A, Kluger Y, Savchenko A, Cort JR, Booth V, Mackereth CD, Saridakis V, Ekiel I, Kozlov G, Maxwell KL, Wu N, McIntosh LP, Gehring K, ... ... Arrowsmith CH, et al. Structural proteomics of an archaeon. Nature Structural Biology. 7: 903-9. PMID 11017201 DOI: 10.1038/82823  0.637
2000 Cort JR, Yee A, Edwards AM, Arrowsmith CH, Kennedy MA. Structure-based functional classification of hypothetical protein MTH538 from Methanobacterium thermoautotrophicum Journal of Molecular Biology. 302: 189-203. PMID 10964569 DOI: 10.1006/Jmbi.2000.4052  0.324
2000 Noolandi J, Davison TS, Volkel AR, Nie X, Kay C, Arrowsmith CH. A meanfield approach to the thermodynamics of a protein-solvent system with application to the oligomerization of the tumor suppressor p53. Proceedings of the National Academy of Sciences of the United States of America. 97: 9955-60. PMID 10944184 DOI: 10.1073/Pnas.160075697  0.712
2000 Szymczyna BR, Arrowsmith CH. DNA binding specificity studies of four ETS proteins support an indirect read-out mechanism of protein-DNA recognition. The Journal of Biological Chemistry. 275: 28363-70. PMID 10867009 DOI: 10.1074/Jbc.M004294200  0.737
2000 Yee A, Booth V, Dharamsi A, Engel A, Edwards AM, Arrowsmith CH. Solution structure of the RNA polymerase subunit RPB5 from Methanobacterium thermoautotrophicum Proceedings of the National Academy of Sciences of the United States of America. 97: 6311-6315. PMID 10841538 DOI: 10.1073/Pnas.97.12.6311  0.639
2000 Booth V, Koth CM, Edwards AM, Arrowsmith CH. Structure of a conserved domain common to the transcription factors TFIIS, Elongin A, and CRSP70 Journal of Biological Chemistry. 275: 31266-31268. PMID 10811649 DOI: 10.1074/Jbc.M002595200  0.64
1999 Chi SW, Ayed A, Arrowsmith CH. Solution structure of a conserved C-terminal domain of p73 with structural homology to the SAM domain. The Embo Journal. 18: 4438-45. PMID 10449409 DOI: 10.1093/emboj/18.16.4438  0.354
1999 Botuyan MV, Koth CM, Mer G, Chakrabartty A, Conaway JW, Conaway RC, Edwards AM, Arrowsmith CH, Chazin WJ. Binding of elongin A or a von Hippel-Lindau peptide stabilizes the structure of yeast elongin C Proceedings of the National Academy of Sciences of the United States of America. 96: 9033-9038. PMID 10430890 DOI: 10.1073/Pnas.96.16.9033  0.314
1999 Davison TS, Vagner C, Kaghad M, Ayed A, Caput D, Arrowsmith CH. p73 and p63 are homotetramers capable of weak heterotypic interactions with each other but not with p53. The Journal of Biological Chemistry. 274: 18709-14. PMID 10373484 DOI: 10.1074/Jbc.274.26.18709  0.694
1998 Davison TS, Yin P, Nie E, Kay C, Arrowsmith CH. Characterization of the oligomerization defects of two p53 mutants found in families with Li-Fraumeni and Li-Fraumeni-like syndrome. Oncogene. 17: 651-6. PMID 9704931 DOI: 10.1038/Sj.Onc.1202062  0.714
1998 Shan X, Gardner KH, Muhandiram DR, Kay LE, Arrowsmith CH. Subunit-specific backbone NMR assignments of a 64 kDa trp repressor/DNA complex: a role for N-terminal residues in tandem binding. Journal of Biomolecular Nmr. 11: 307-18. PMID 9691278 DOI: 10.1023/A:1008257803130  0.321
1998 Yee AA, Yin P, Siderovski DP, Mak TW, Litchfield DW, Arrowsmith CH. Cooperative interaction between the DNA-binding domains of PU.1 and IRF4 Journal of Molecular Biology. 279: 1075-1083. PMID 9642085 DOI: 10.1006/Jmbi.1998.1838  0.308
1997 Vaziri H, West MD, Allsopp RC, Davison TS, Wu YS, Arrowsmith CH, Poirier GG, Benchimol S. ATM-dependent telomere loss in aging human diploid fibroblasts and DNA damage lead to the post-translational activation of p53 protein involving poly(ADP-ribose) polymerase. The Embo Journal. 16: 6018-33. PMID 9312059 DOI: 10.1093/Emboj/16.19.6018  0.705
1994 Zhang H, Zhao D, Revington M, Lee W, Jia X, Arrowsmith C, Jardetzky O. The solution structures of the trp repressor-operator DNA complex. Journal of Molecular Biology. 238: 592-614. PMID 8176748 DOI: 10.1006/Jmbi.1994.1317  0.376
1994 Lee W, Harvey TS, Yin Y, Yau P, Litchfield D, Arrowsmith CH. Solution structure of the tetrameric minimum transforming domain of p53 Nature Structural Biology. 1: 877-890. PMID 7773777 DOI: 10.1038/Nsb1294-877  0.31
1991 Arrowsmith C, Pachter R, Altman R, Jardetzky O. The solution structures of Escherichia coli trp repressor and trp aporepressor at an intermediate resolution. European Journal of Biochemistry / Febs. 202: 53-66. PMID 1935980 DOI: 10.1111/J.1432-1033.1991.Tb16344.X  0.417
1991 Czaplicki J, Arrowsmith C, Jardetzky O. Segmental differences in the stability of the trp-repressor peptide backbone. Journal of Biomolecular Nmr. 1: 349-61. PMID 1841704 DOI: 10.1007/Bf02192859  0.333
1989 Arrowsmith CH, Carey J, Treat-Clemons L, Jardetzky O. NMR assignments for the amino-terminal residues of trp repressor and their role in DNA binding. Biochemistry. 28: 3875-9. PMID 2665811 DOI: 10.1021/Bi00435A037  0.317
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