Dwayne Barber - Publications

Medical Biophysics University of Toronto, Toronto, ON, Canada 
Oncology, Molecular Biology, Cell Biology

49 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Huang J, Liu Y, Au BC, Barber DL, Arruda A, Schambach A, Rothe M, Minden MD, Paige CJ, Medin JA. Preclinical validation: LV/IL-12 transduction of patient leukemia cells for immunotherapy of AML. Molecular Therapy. Methods & Clinical Development. 3: 16074. PMID 27933304 DOI: 10.1038/mtm.2016.74  0.36
2015 Rotin LE, Gronda M, MacLean N, Hurren R, Wang X, Lin FH, Wrana J, Datti A, Barber DL, Minden MD, Slassi M, Schimmer AD. Ibrutinib synergizes with poly(ADP-ribose) glycohydrolase inhibitors to induce cell death in AML cells via a BTK-independent mechanism. Oncotarget. PMID 26624983 DOI: 10.18632/oncotarget.6409  0.56
2013 Anderson NM, Javadi M, Berndl E, Berberovic Z, Bailey ML, Huang K, Flenniken AM, Osborne LR, Adamson SL, Rossant J, Carter-Su C, Wang C, McNagny KM, Paulson RF, Minden MD, ... ... Barber DL, et al. Enu mutagenesis identifies a novel platelet phenotype in a loss-of-function Jak2 allele. Plos One. 8: e75472. PMID 24086539 DOI: 10.1371/Journal.Pone.0075472  0.56
2013 Javadi M, Richmond TD, Huang K, Barber DL. CBL linker region and RING finger mutations lead to enhanced granulocyte-macrophage colony-stimulating factor (GM-CSF) signaling via elevated levels of JAK2 and LYN. The Journal of Biological Chemistry. 288: 19459-70. PMID 23696637 DOI: 10.1074/jbc.M113.475087  0.56
2013 Gillis LC, Berry DM, Minden MD, McGlade CJ, Barber DL. Gads (Grb2-related adaptor downstream of Shc) is required for BCR-ABL-mediated lymphoid leukemia. Leukemia. 27: 1666-76. PMID 23399893 DOI: 10.1038/leu.2013.40  0.56
2013 Badger-Brown KM, Gillis LC, Bailey ML, Penninger JM, Barber DL. CBL-B is required for leukemogenesis mediated by BCR-ABL through negative regulation of bone marrow homing. Leukemia. 27: 1146-54. PMID 23160449 DOI: 10.1038/leu.2012.331  0.56
2012 Marit MR, Chohan M, Matthew N, Huang K, Kuntz DA, Rose DR, Barber DL. Random mutagenesis reveals residues of JAK2 critical in evading inhibition by a tyrosine kinase inhibitor. Plos One. 7: e43437. PMID 22916261 DOI: 10.1371/journal.pone.0043437  0.56
2012 Sasaki M, Knobbe CB, Munger JC, Lind EF, Brenner D, Brüstle A, Harris IS, Holmes R, Wakeham A, Haight J, You-Ten A, Li WY, Schalm S, Su SM, Virtanen C, ... ... Barber DL, et al. IDH1(R132H) mutation increases murine haematopoietic progenitors and alters epigenetics. Nature. 488: 656-9. PMID 22763442 DOI: 10.1038/Nature11323  0.56
2012 Javadi M, Hofstätter E, Stickle N, Beattie BK, Jaster R, Carter-Su C, Barber DL. The SH2B1 adaptor protein associates with a proximal region of the erythropoietin receptor. The Journal of Biological Chemistry. 287: 26223-34. PMID 22669948 DOI: 10.1074/jbc.M112.382721  0.56
2012 Barber DL. Chopped and diced: Dicer1 deletion generates myeloid dysplasia. Blood. 119: 4581-2. PMID 22596169 DOI: 10.1182/blood-2012-04-415034  0.56
2012 Barber DL. GRPling with PTEN. Blood. 119: 648-9. PMID 22262740 DOI: 10.1182/blood-2011-11-382614  0.56
2012 Anderson NM, Berberovic Z, Berndl E, Bailey ML, Flenniken AM, Osborne LR, Adamson SL, Rossant J, Wang C, Minden MD, McNagny KM, Paulson RF, Barber DL, Stanford WL. Cytopenia induction by 5-fluorouracil identifies thrombopoietic mutants in sensitized ENU mutagenesis screens. Experimental Hematology. 40: 48-60. PMID 21924221 DOI: 10.1016/J.Exphem.2011.09.007  0.56
2011 Kim H, Gillis LC, Jarvis JD, Yang S, Huang K, Der S, Barber DL. Tyrosine kinase chromosomal translocations mediate distinct and overlapping gene regulation events. Bmc Cancer. 11: 528. PMID 22204395 DOI: 10.1186/1471-2407-11-528  0.56
2011 Russell RC, Sufan RI, Zhou B, Heir P, Bunda S, Sybingco SS, Greer SN, Roche O, Heathcote SA, Chow VW, Boba LM, Richmond TD, Hickey MM, Barber DL, Cheresh DA, et al. Loss of JAK2 regulation via a heterodimeric VHL-SOCS1 E3 ubiquitin ligase underlies Chuvash polycythemia. Nature Medicine. 17: 845-53. PMID 21685897 DOI: 10.1038/nm.2370  0.56
2011 Hughes MR, Anderson N, Maltby S, Wong J, Berberovic Z, Birkenmeier CS, Haddon DJ, Garcha K, Flenniken A, Osborne LR, Adamson SL, Rossant J, Peters LL, Minden MD, Paulson RF, ... ... Barber DL, et al. A novel ENU-generated truncation mutation lacking the spectrin-binding and C-terminal regulatory domains of Ank1 models severe hemolytic hereditary spherocytosis. Experimental Hematology. 39: 305-20, 320.e1-2. PMID 21193012 DOI: 10.1016/J.Exphem.2010.12.009  0.56
2010 Lakhanpal GK, Vecchiarelli-Federico LM, Li YJ, Cui JW, Bailey ML, Spaner DE, Dumont DJ, Barber DL, Ben-David Y. The inositol phosphatase SHIP-1 is negatively regulated by Fli-1 and its loss accelerates leukemogenesis. Blood. 116: 428-36. PMID 20445019 DOI: 10.1182/blood-2009-10-250217  0.56
2010 Javed MJ, Richmond TD, Barber DL. Cytokine receptor signaling Handbook of Cell Signaling, 2/E. 2: 451-466. DOI: 10.1016/B978-0-12-374145-5.00063-2  0.56
2009 Barber DL. Truth or dare: role of Liar in EPO-dependent signaling. Blood. 113: 3650-1. PMID 19372263 DOI: 10.1182/blood-2009-01-198861  0.56
2009 Hirschler-Laszkiewicz I, Tong Q, Conrad K, Zhang W, Flint WW, Barber AJ, Barber DL, Cheung JY, Miller BA. TRPC3 activation by erythropoietin is modulated by TRPC6. The Journal of Biological Chemistry. 284: 4567-81. PMID 19074769 DOI: 10.1074/Jbc.M804734200  0.56
2008 Tong Q, Hirschler-Laszkiewicz I, Zhang W, Conrad K, Neagley DW, Barber DL, Cheung JY, Miller BA. TRPC3 is the erythropoietin-regulated calcium channel in human erythroid cells. The Journal of Biological Chemistry. 283: 10385-95. PMID 18276585 DOI: 10.1074/jbc.M710231200  0.56
2007 Huang Z, Richmond TD, Muntean AG, Barber DL, Weiss MJ, Crispino JD. STAT1 promotes megakaryopoiesis downstream of GATA-1 in mice. The Journal of Clinical Investigation. 117: 3890-9. PMID 18060035 DOI: 10.1172/Jci33010  0.56
2007 Mao X, Stewart AK, Hurren R, Datti A, Zhu X, Zhu Y, Shi C, Lee K, Tiedemann R, Eberhard Y, Trudel S, Liang S, Corey SJ, Gillis LC, Barber DL, et al. A chemical biology screen identifies glucocorticoids that regulate c-maf expression by increasing its proteasomal degradation through up-regulation of ubiquitin. Blood. 110: 4047-54. PMID 17875808 DOI: 10.1182/blood-2007-05-088666  0.56
2007 Corey SJ, Minden MD, Barber DL, Kantarjian H, Wang JC, Schimmer AD. Myelodysplastic syndromes: the complexity of stem-cell diseases. Nature Reviews. Cancer. 7: 118-29. PMID 17251918 DOI: 10.1038/nrc2047  0.56
2007 Oh SY, Zheng T, Bailey ML, Barber DL, Schroeder JT, Kim YK, Zhu Z. Src homology 2 domain-containing inositol 5-phosphatase 1 deficiency leads to a spontaneous allergic inflammation in the murine lung. The Journal of Allergy and Clinical Immunology. 119: 123-31. PMID 17208593 DOI: 10.1016/j.jaci.2006.08.029  0.56
2006 Braude I, Vukovic B, Prasad M, Marrano P, Turley S, Barber D, Zielenska M, Squire JA. Large scale copy number variation (CNV) at 14q12 is associated with the presence of genomic abnormalities in neoplasia Bmc Genomics. 7. PMID 16756668 DOI: 10.1186/1471-2164-7-138  0.56
2006 Zhang W, Hirschler-Laszkiewicz I, Tong Q, Conrad K, Sun SC, Penn L, Barber DL, Stahl R, Carey DJ, Cheung JY, Miller BA. TRPM2 is an ion channel that modulates hematopoietic cell death through activation of caspases and PARP cleavage. American Journal of Physiology. Cell Physiology. 290: C1146-59. PMID 16306129 DOI: 10.1152/ajpcell.00205.2005  0.56
2005 Halupa A, Chohan M, Stickle NH, Beattie BK, Miller BA, Barber DL. Erythropoietin receptor Y479 couples to ERK1/2 activation via recruitment of phospholipase Cgamma. Experimental Cell Research. 309: 1-11. PMID 15953601 DOI: 10.1016/j.yexcr.2005.04.030  0.56
2005 Richmond TD, Chohan M, Barber DL. Turning cells red: signal transduction mediated by erythropoietin. Trends in Cell Biology. 15: 146-55. PMID 15752978 DOI: 10.1016/j.tcb.2005.01.007  0.56
2005 Chu X, Tong Q, Wozney J, Zhang W, Cheung JY, Conrad K, Mazack V, Stahl R, Barber DL, Miller BA. Identification of an N-terminal TRPC2 splice variant which inhibits calcium influx. Cell Calcium. 37: 173-82. PMID 15589997 DOI: 10.1016/j.ceca.2004.08.005  0.32
2005 Halupa A, Bailey ML, Huang K, Iscove NN, Levy DE, Barber DL. A novel role for STAT1 in regulating murine erythropoiesis: deletion of STAT1 results in overall reduction of erythroid progenitors and alters their distribution. Blood. 105: 552-61. PMID 15213094 DOI: 10.1182/blood-2003-09-3237  0.56
2004 Tong Q, Chu X, Cheung JY, Conrad K, Stahl R, Barber DL, Mignery G, Miller BA. Erythropoietin-modulated calcium influx through TRPC2 is mediated by phospholipase Cgamma and IP3R. American Journal of Physiology. Cell Physiology. 287: C1667-78. PMID 15329338 DOI: 10.1152/ajpcell.00265.2004  0.56
2004 Chen J, Jacobs-Helber SM, Barber DL, Sawyer ST. Erythropoietin-dependent autocrine secretion of tumor necrosis factor-alpha in hematopoietic cells modulates proliferation via MAP kinase--ERK-1/2 and does not require tyrosine docking sites in the EPO receptor. Experimental Cell Research. 298: 155-66. PMID 15242770 DOI: 10.1016/j.yexcr.2004.04.009  0.56
2004 Song H, Sondak VK, Barber DL, Reid TJ, Lin J. Modulation of Janus kinase 2 by cisplatin in cancer cells. International Journal of Oncology. 24: 1017-26. PMID 15010843  0.56
2004 Chu X, Tong Q, Cheung JY, Wozney J, Conrad K, Mazack V, Zhang W, Stahl R, Barber DL, Miller BA. Interaction of TRPC2 and TRPC6 in erythropoietin modulation of calcium influx. The Journal of Biological Chemistry. 279: 10514-22. PMID 14699131 DOI: 10.1074/jbc.M308478200  0.32
2003 Jacobs-Helber SM, Roh KH, Bailey D, Dessypris EN, Ryan JJ, Chen J, Wickrema A, Barber DL, Dent P, Sawyer ST. Tumor necrosis factor-alpha expressed constitutively in erythroid cells or induced by erythropoietin has negative and stimulatory roles in normal erythropoiesis and erythroleukemia. Blood. 101: 524-31. PMID 12393629 DOI: 10.1182/blood-2001-11-0084  0.56
2002 Lin Y, Brown L, Hedley DW, Barber DL, Benchimol S. The death-promoting activity of p53 can be inhibited by distinct signaling pathways. Blood. 100: 3990-4000. PMID 12393587 DOI: 10.1182/blood-2002-02-0504  0.56
2002 Chu X, Cheung JY, Barber DL, Birnbaumer L, Rothblum LI, Conrad K, Abrasonis V, Chan YM, Stahl R, Carey DJ, Miller BA. Erythropoietin modulates calcium influx through TRPC2. The Journal of Biological Chemistry. 277: 34375-82. PMID 12167663 DOI: 10.1074/jbc.M205541200  0.56
2002 Ho JM, Nguyen MH, Dierov JK, Badger KM, Beattie BK, Tartaro P, Haq R, Zanke BW, Carroll MP, Barber DL. TEL-JAK2 constitutively activates the extracellular signal-regulated kinase (ERK), stress-activated protein/Jun kinase (SAPK/JNK), and p38 signaling pathways. Blood. 100: 1438-48. PMID 12149229  0.56
2002 Rottapel R, Ilangumaran S, Neale C, La Rose J, Ho JM, Nguyen MH, Barber D, Dubreuil P, de Sepulveda P. The tumor suppressor activity of SOCS-1. Oncogene. 21: 4351-62. PMID 12080466 DOI: 10.1038/sj.onc.1205537  0.56
2002 Simoncic PD, Lee-Loy A, Barber DL, Tremblay ML, McGlade CJ. The T cell protein tyrosine phosphatase is a negative regulator of janus family kinases 1 and 3. Current Biology : Cb. 12: 446-53. PMID 11909529 DOI: 10.1016/S0960-9822(02)00697-8  0.56
2002 Haq R, Halupa A, Beattie BK, Mason JM, Zanke BW, Barber DL. Regulation of erythropoietin-induced STAT serine phosphorylation by distinct mitogen-activated protein kinases. The Journal of Biological Chemistry. 277: 17359-66. PMID 11875080 DOI: 10.1074/jbc.M201842200  0.56
2001 Nguyen MH, Ho JM, Beattie BK, Barber DL. TEL-JAK2 mediates constitutive activation of the phosphatidylinositol 3'-kinase/protein kinase B signaling pathway. The Journal of Biological Chemistry. 276: 32704-13. PMID 11435425 DOI: 10.1074/jbc.M103100200  0.56
2001 Zhang MY, Barber DL, Alessi DR, Bell LL, Stine C, Nguyen MH, Beattie BK, Cheung JY, Miller BA. A minimal cytoplasmic subdomain of the erythropoietin receptor mediates p70 S6 kinase phosphorylation. Experimental Hematology. 29: 432-40. PMID 11301183 DOI: 10.1016/S0301-472X(00)00681-0  0.56
2001 Barber DL, Beattie BK, Mason JM, Nguyen MHH, Yoakim M, Neel BG, D'Andrea AD, Frank DA. A common epitope is shared by activated signal transducer and activator of transcription-5 (STAT5) and the phosphorylated erythropoietin receptor: Implications for the docking model of STAT activation Blood. 97: 2230-2237. PMID 11290583 DOI: 10.1182/blood.V97.8.2230  0.56
2000 Mason JM, Beattie BK, Liu Q, Dumont DJ, Barber DL. The SH2 inositol 5-phosphatase Ship1 is recruited in an SH2-dependent manner to the erythropoietin receptor Journal of Biological Chemistry. 275: 4398-4406. PMID 10660611 DOI: 10.1074/jbc.275.6.4398  0.56
1999 Miller BA, Barber DL, Bell LL, Beattie BK, Zhang MY, Neel BG, Yoakim M, Rothblum LI, Cheung JY. Identification of the erythropoietin receptor domain required for calcium channel activation Journal of Biological Chemistry. 274: 20465-20472. PMID 10400674 DOI: 10.1074/jbc.274.29.20465  0.56
1997 Barber DL, Mason JM, Fukazawa T, Reedquist KA, Druker BJ, Band H, D'Andrea AD. Erythropoietin and interleukin-3 activate tyrosine phosphorylation of CBL and association with CRK adaptor proteins. Blood. 89: 3166-74. PMID 9129019  0.56
1994 Barber DL, Demartino JC, Showers MO, D'Andrea AD. A dominant negative erythropoietin (EPO) receptor inhibits EPO-dependent growth and blocks F-gp55-dependent transformation Molecular and Cellular Biology. 14: 2257-2265. PMID 8139531 DOI: 10.1128/MCB.14.4.2257  0.56
1994 Barber DL, D'Andrea AD. Erythropoietin and interleukin-2 activate distinct JAK kinase family members Molecular and Cellular Biology. 14: 6506-6514. PMID 7935373 DOI: 10.1128/MCB.14.10.6506  0.56
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