Marios Giannakis, Ph.D. - Publications

Affiliations: 
2009 Washington University, Saint Louis, St. Louis, MO 
Area:
Microbiology Biology, Genetics, Cell Biology

100 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Thomas CE, Georgeson P, Qu C, Steinfelder RS, Buchanan DD, Song M, Harrison TA, Um CY, Hullar MA, Jenkins MA, Van Guelpen B, Lynch BM, Melaku YA, Huyghe JR, Aglago EK, ... ... Giannakis M, et al. Epidemiologic factors in relation to colorectal cancer risk and survival by genotoxic colibactin mutational signature. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. PMID 38252034 DOI: 10.1158/1055-9965.EPI-23-0600  0.342
2023 Zhao M, Lau MC, Haruki K, Väyrynen JP, Gurjao C, Väyrynen SA, Dias Costa A, Borowsky J, Fujiyoshi K, Arima K, Hamada T, Lennerz JK, Fuchs CS, Nishihara R, Chan AT, ... ... Giannakis M, et al. Bayesian risk prediction model for colorectal cancer mortality through integration of clinicopathologic and genomic data. Npj Precision Oncology. 7: 57. PMID 37301916 DOI: 10.1038/s41698-023-00406-8  0.301
2023 Georgeson P, Steinfelder RS, Harrison TA, Pope BJ, Zaidi SH, Qu C, Lin Y, Joo JE, Mahmood K, Clendenning M, Walker R, Aglago EK, Berndt SI, Brenner H, Campbell PT, ... ... Giannakis M, et al. Genotoxic colibactin mutational signature in colorectal cancer is associated with clinicopathological features, specific genomic alterations and better survival. Medrxiv : the Preprint Server For Health Sciences. PMID 37090539 DOI: 10.1101/2023.03.10.23287127  0.366
2023 Ugai T, Haruki K, Harrison TA, Cao Y, Qu C, Chan AT, Campbell PT, Akimoto N, Berndt S, Brenner H, Buchanan DD, Chang-Claude J, Fujiyoshi K, Gallinger SJ, Gunter MJ, ... ... Giannakis M, et al. Molecular Characteristics of Early-Onset Colorectal Cancer According to Detailed Anatomical Locations: Comparison With Later-Onset Cases. The American Journal of Gastroenterology. PMID 36707929 DOI: 10.14309/ajg.0000000000002171  0.326
2023 Tian J, Chen JH, Chao SX, Pelka K, Giannakis M, Hess J, Burke K, Jorgji V, Sindurakar P, Braverman J, Mehta A, Oka T, Huang M, Lieb D, Spurrell M, et al. Combined PD-1, BRAF and MEK inhibition in BRAF colorectal cancer: a phase 2 trial. Nature Medicine. PMID 36702949 DOI: 10.1038/s41591-022-02181-8  0.302
2023 Ugai T, Akimoto N, Haruki K, Harrison TA, Cao Y, Qu C, Chan AT, Campbell PT, Berndt SI, Buchanan DD, Cross AJ, Diergaarde B, Gallinger SJ, Gunter MJ, Harlid S, ... ... Giannakis M, et al. Prognostic role of detailed colorectal location and tumor molecular features: analyses of 13,101 colorectal cancer patients including 2994 early-onset cases. Journal of Gastroenterology. PMID 36648535 DOI: 10.1007/s00535-023-01955-2  0.363
2022 Yang K, Cao Y, Gurjao C, Liu Y, Guo CG, Lo CH, Zong X, Drew D, Geraghty C, Prezioso E, Moore M, Williams C, Riley T, Saul M, Ogino S, ... Giannakis M, et al. Clinical and Genomic Characterization of Interval Colorectal Cancer in Three Prospective Cohorts. Gastroenterology. PMID 35970241 DOI: 10.1053/j.gastro.2022.08.020  0.323
2022 Barfield R, Qu C, Steinfelder RS, Zeng C, Harrison TA, Brezina S, Buchanan DD, Campbell PT, Casey G, Gallinger S, Giannakis M, Gruber SB, Gsur A, Hsu L, Huyghe JR, et al. Association between germline variants and somatic mutations in colorectal cancer. Scientific Reports. 12: 10207. PMID 35715570 DOI: 10.1038/s41598-022-14408-2  0.336
2022 Fang L, Ford-Roshon D, Russo M, O'Brien C, Xiong X, Gurjao C, Grandclaudon M, Raghavan S, Corsello SM, Carr SA, Udeshi ND, Berstler J, Sicinska E, Ng K, Giannakis M. RNF43 G659fs is an oncogenic colorectal cancer mutation and sensitizes tumor cells to PI3K/mTOR inhibition. Nature Communications. 13: 3181. PMID 35676246 DOI: 10.1038/s41467-022-30794-7  0.324
2022 Georgeson P, Harrison TA, Pope BJ, Zaidi SH, Qu C, Steinfelder RS, Lin Y, Joo JE, Mahmood K, Clendenning M, Walker R, Amitay EL, Berndt SI, Brenner H, Campbell PT, ... ... Giannakis M, et al. Identifying colorectal cancer caused by biallelic MUTYH pathogenic variants using tumor mutational signatures. Nature Communications. 13: 3254. PMID 35668106 DOI: 10.1038/s41467-022-30916-1  0.372
2022 Akimoto N, Väyrynen JP, Zhao M, Ugai T, Fujiyoshi K, Borowsky J, Zhong R, Haruki K, Arima K, Lau MC, Kishikawa J, Twombly TS, Takashima Y, Song M, Zhang X, ... ... Giannakis M, et al. Desmoplastic Reaction, Immune Cell Response, and Prognosis in Colorectal Cancer. Frontiers in Immunology. 13: 840198. PMID 35392092 DOI: 10.3389/fimmu.2022.840198  0.33
2022 Harlid S, Van Guelpen B, Qu C, Gylling B, Aglago EK, Amitay EL, Brenner H, Buchanan DD, Campbell PT, Cao Y, Chan AT, Chang-Claude J, Drew DA, Figueiredo JC, French AJ, ... ... Giannakis M, et al. Diabetes mellitus in relation to colorectal tumor molecular subtypes - a pooled analysis of more than 9,000 cases. International Journal of Cancer. PMID 35383926 DOI: 10.1002/ijc.34015  0.34
2022 Ugai T, Haruki K, Väyrynen JP, Borowsky J, Fujiyoshi K, Lau MC, Akimoto N, Zhong R, Kishikawa J, Arima K, Shi SS, Zhao M, Fuchs CS, Zhang X, Giannakis M, et al. Coffee Intake of Colorectal Cancer Patients and Prognosis According to Histopathologic Lymphocytic Reaction and T-Cell Infiltrates. Mayo Clinic Proceedings. 97: 124-133. PMID 34996545 DOI: 10.1016/j.mayocp.2021.09.007  0.323
2021 Kim M, Ly SH, Xie Y, Duronio GN, Ford-Roshon D, Hwang JH, Sulahian R, Rennhack JP, So J, Gjoerup O, Talamas JA, Grandclaudon M, Long HW, Doench JG, Sethi NS, ... Giannakis M, et al. YAP1 and PRDM14 converge to promote cell survival and tumorigenesis. Developmental Cell. PMID 34990589 DOI: 10.1016/j.devcel.2021.12.006  0.307
2021 Väyrynen JP, Haruki K, Lau MC, Väyrynen SA, Ugai T, Akimoto N, Zhong R, Zhao M, Dias Costa A, Borowsky J, Bell P, Takashima Y, Fujiyoshi K, Arima K, Kishikawa J, ... ... Giannakis M, et al. Spatial organization and prognostic significance of NK and NKT-like cells via multimarker analysis of the colorectal cancer microenvironment. Cancer Immunology Research. PMID 34937729 DOI: 10.1158/2326-6066.CIR-21-0772  0.31
2021 Chen B, Scurrah CR, McKinley ET, Simmons AJ, Ramirez-Solano MA, Zhu X, Markham NO, Heiser CN, Vega PN, Rolong A, Kim H, Sheng Q, Drewes JL, Zhou Y, Southard-Smith AN, ... ... Giannakis M, et al. Differential pre-malignant programs and microenvironment chart distinct paths to malignancy in human colorectal polyps. Cell. PMID 34910928 DOI: 10.1016/j.cell.2021.11.031  0.376
2021 Pelka K, Hofree M, Chen JH, Sarkizova S, Pirl JD, Jorgji V, Bejnood A, Dionne D, Ge WH, Xu KH, Chao SX, Zollinger DR, Lieb DJ, Reeves JW, Fuhrman CA, ... ... Giannakis M, et al. Spatially organized multicellular immune hubs in human colorectal cancer. Cell. PMID 34450029 DOI: 10.1016/j.cell.2021.08.003  0.313
2021 Gurjao C, Zhong R, Haruki K, Li YY, Spurr LF, Lee-Six H, Reardon B, Ugai T, Zhang X, Cherniack AD, Song M, Van Allen EM, Meyerhardt JA, Nowak JA, Giovannucci EL, ... ... Giannakis M, et al. Discovery and features of an alkylating signature in colorectal cancer. Cancer Discovery. PMID 34140290 DOI: 10.1158/2159-8290.CD-20-1656  0.339
2021 Adib E, Nassar AH, Akl EW, Abou Alaiwi S, Nuzzo PV, Mouhieddine TH, Sonpavde G, Haddad RI, Mouw KW, Giannakis M, Hodi FS, Shukla SA, Gusev A, Braun DA, Choueiri TK, et al. Alterations and Response to Immunotherapy in Solid Tumors. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 34074656 DOI: 10.1158/1078-0432.CCR-21-0575  0.314
2021 Väyrynen JP, Haruki K, Väyrynen SA, Lau MC, Dias Costa A, Borowsky J, Zhao M, Ugai T, Kishikawa J, Akimoto N, Zhong R, Shi S, Chang TW, Fujiyoshi K, Arima K, ... ... Giannakis M, et al. Prognostic significance of myeloid immune cells and their spatial distribution in the colorectal cancer microenvironment. Journal For Immunotherapy of Cancer. 9. PMID 33931472 DOI: 10.1136/jitc-2020-002297  0.349
2020 Ugai T, Haruki K, Väyrynen JP, Zhong R, Borowsky J, Fujiyoshi K, Lau MC, Zhao M, Akimoto N, Chang TW, Kishikawa J, Arima K, Shi SS, Gu S, Fuchs CS, ... ... Giannakis M, et al. Coffee Intake and Colorectal Cancer Incidence According to T-Cell Response. Jnci Cancer Spectrum. 4: pkaa068. PMID 33409450 DOI: 10.1093/Jncics/Pkaa068  0.406
2020 Fujiyoshi K, Chen Y, Haruki K, Ugai T, Kishikawa J, Hamada T, Liu L, Arima K, Borowsky J, Väyrynen JP, Zhao M, Lau MC, Gu S, Shi S, Akimoto N, ... ... Giannakis M, et al. Smoking Status at Diagnosis and Colorectal Cancer Prognosis According to Tumor Lymphocytic Reaction. Jnci Cancer Spectrum. 4: pkaa040. PMID 32923934 DOI: 10.1093/Jncics/Pkaa040  0.423
2020 Hidaka A, Harrison TA, Cao Y, Sakoda LC, Barfield R, Giannakis M, Song M, Phipps AI, Figueiredo JC, Zaidi SH, Toland AE, Amitay EL, Berndt SI, Borozan I, Chan AT, et al. Intake of dietary fruit, vegetables, and fiber and risk of colorectal cancer according to molecular subtypes: A pooled analysis of 9 studies. Cancer Research. PMID 32816852 DOI: 10.1158/0008-5472.Can-20-0168  0.39
2020 Hinze L, Labrosse R, Degar J, Han T, Schatoff EM, Schreek S, Karim S, McGuckin C, Sacher JR, Wagner F, Stanulla M, Yuan C, Sicinska E, Giannakis M, Ng K, et al. Exploiting the Therapeutic Interaction of WNT Pathway Activation and Asparaginase for Colorectal Cancer Therapy. Cancer Discovery. PMID 32703769 DOI: 10.1158/2159-8290.Cd-19-1472  0.359
2020 Zaidi SH, Harrison TA, Phipps AI, Steinfelder R, Trinh QM, Qu C, Banbury BL, Georgeson P, Grasso CS, Giannakis M, Adams JB, Alwers E, Amitay EL, Barfield RT, Berndt SI, et al. Landscape of somatic single nucleotide variants and indels in colorectal cancer and impact on survival. Nature Communications. 11: 3644. PMID 32686686 DOI: 10.1038/S41467-020-17386-Z  0.429
2020 Fujiyoshi K, Väyrynen JP, Borowsky J, Papke DJ, Arima K, Haruki K, Kishikawa J, Akimoto N, Ugai T, Lau MC, Gu S, Shi S, Zhao M, Da Silva AFL, Twombly TS, ... ... Giannakis M, et al. Tumour budding, poorly differentiated clusters, and T-cell response in colorectal cancer. Ebiomedicine. 57: 102860. PMID 32652320 DOI: 10.1016/J.Ebiom.2020.102860  0.363
2020 Väyrynen JP, Lau MC, Haruki K, Väyrynen SA, Dias Costa A, Borowsky J, Zhao M, Fujiyoshi K, Arima K, Twombly TS, Kishikawa J, Gu S, Aminmozaffari S, Shi S, Baba Y, ... ... Giannakis M, et al. Prognostic significance of immune cell populations identified by machine learning in colorectal cancer using routine hematoxylin & eosin stained sections. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 32439699 DOI: 10.1158/1078-0432.Ccr-20-0071  0.453
2020 Abou Alaiwi S, Nassar AH, Xie W, Bakouny Z, Berchuck JE, Braun DA, Baca SC, Nuzzo PV, Flippot R, Mouhieddine TH, Spurr LF, Li YY, Li T, Flaifel A, Steinharter JA, ... ... Giannakis M, et al. Mammalian SWI/SNF complex genomic alterations and immune checkpoint blockade in solid tumors. Cancer Immunology Research. PMID 32321774 DOI: 10.1158/2326-6066.Cir-19-0866  0.418
2020 Arima K, Lau MC, Zhao M, Haruki K, Kosumi K, Mima K, Gu M, Väyrynen JP, Twombly TS, Baba Y, Fujiyoshi K, Kishikawa J, Guo C, Baba H, Richards WG, ... ... Giannakis M, et al. Metabolic Profiling of Formalin-Fixed Paraffin-Embedded Tissues Discriminates Normal Colon from Colorectal Cancer. Molecular Cancer Research : McR. PMID 32165453 DOI: 10.1158/1541-7786.Mcr-19-1091  0.321
2020 Rendo V, Stoimenov I, Mateus A, Sjöberg E, Svensson R, Gustavsson AL, Johansson L, Ng A, OʼBrien C, Giannakis M, Artursson P, Nygren P, Cheong I, Sjöblom T. Exploiting loss of heterozygosity for allele-selective colorectal cancer chemotherapy. Nature Communications. 11: 1308. PMID 32161261 DOI: 10.1038/S41467-020-15111-4  0.447
2020 Haruki K, Kosumi K, Li P, Arima K, Väyrynen JP, Lau MC, Twombly TS, Hamada T, Glickman JN, Fujiyoshi K, Chen Y, Du C, Guo C, Väyrynen SA, Dias Costa A, ... ... Giannakis M, et al. An integrated analysis of lymphocytic reaction, tumour molecular characteristics and patient survival in colorectal cancer. British Journal of Cancer. PMID 32157241 DOI: 10.1038/S41416-020-0780-3  0.397
2020 Pleguezuelos-Manzano C, Puschhof J, Huber AR, van Hoeck A, Wood HM, Nomburg J, Gurjao C, Manders F, Dalmasso G, Stege PB, Paganelli FL, Geurts MH, Beumer J, Mizutani T, van der Linden R, ... ... Giannakis M, et al. Mutational signature in colorectal cancer caused by genotoxic pks E. coli. Nature. PMID 32106218 DOI: 10.1038/S41586-020-2080-8  0.401
2020 Wei XX, McGregor BA, Lee RJ, Gao X, Kilbridge KL, Preston MA, Mossanen M, Ingham MD, Steele GS, Klein A, Allen EMV, Severgnini M, Giannakis M, Sonpavde G. Durvalumab as neoadjuvant therapy for muscle-invasive bladder cancer: Preliminary results from the Bladder Cancer Signal Seeking Trial (BLASST)-2. Journal of Clinical Oncology. 38: 507-507. DOI: 10.1200/Jco.2020.38.6_Suppl.507  0.342
2020 Jakubowski C, Collins NB, Sugar EA, Berg M, Cao H, Giannakis M, Jaffee EM, Azad NS. A phase I/II study of PI3Kinase inhibition with copanlisib combined with the anti-PD-1 antibody nivolumab in relapsed/refractory solid tumors with expansions in MSS colorectal cancer. Journal of Clinical Oncology. 38: TPS4114-TPS4114. DOI: 10.1200/Jco.2020.38.15_Suppl.Tps4114  0.421
2019 Haruki K, Kosumi K, Hamada T, Twombly TS, Väyrynen JP, Kim SA, Masugi Y, Qian ZR, Mima K, Baba Y, da Silva A, Borowsky J, Arima K, Fujiyoshi K, Lau MC, ... ... Giannakis M, et al. Association of autophagy status with amount of Fusobacterium nucleatum in colorectal cancer. The Journal of Pathology. PMID 31880318 DOI: 10.1002/Path.5381  0.393
2019 Shi Y, Liu L, Hamada T, Nowak JA, Giannakis M, Ma Y, Song M, Nevo D, Kosumi K, Gu M, Kim SA, Morikawa T, Wu K, Sui J, Papantoniou K, et al. Night-shift work duration and risk of colorectal cancer according to IRS1 and IRS2 expression. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. PMID 31666286 DOI: 10.1158/1055-9965.Epi-19-0325  0.327
2019 Li H, Bullock K, Gurjao C, Braun D, Shukla SA, Bossé D, Lalani AA, Gopal S, Jin C, Horak C, Wind-Rotolo M, Signoretti S, McDermott DF, Freeman GJ, Van Allen EM, ... ... Giannakis M, et al. Metabolomic adaptations and correlates of survival to immune checkpoint blockade. Nature Communications. 10: 4346. PMID 31554815 DOI: 10.1038/S41467-019-12361-9  0.348
2019 Gurjao C, Liu D, Hofree M, AlDubayan SH, Wakiro I, Su MJ, Felt K, Gjini E, Brais LK, Rotem A, Rosenthal MH, Rozenblatt-Rosen O, Rodig S, Ng K, Van Allen EM, ... ... Giannakis M, et al. Intrinsic Resistance to Immune Checkpoint Blockade in a Mismatch Repair Deficient Colorectal Cancer. Cancer Immunology Research. PMID 31217164 DOI: 10.1158/2326-6066.Cir-18-0683  0.474
2019 Li H, Ning S, Ghandi M, Kryukov GV, Gopal S, Deik A, Souza A, Pierce K, Keskula P, Hernandez D, Ann J, Shkoza D, Apfel V, Zou Y, Vazquez F, ... ... Giannakis M, et al. The landscape of cancer cell line metabolism. Nature Medicine. 25: 850-860. PMID 31068703 DOI: 10.1038/S41591-019-0404-8  0.423
2019 Chan EM, Shibue T, McFarland JM, Gaeta B, Ghandi M, Dumont N, Gonzalez A, McPartlan JS, Li T, Zhang Y, Bin Liu J, Lazaro JB, Gu P, Piett CG, Apffel A, ... ... Giannakis M, et al. WRN helicase is a synthetic lethal target in microsatellite unstable cancers. Nature. PMID 30971823 DOI: 10.1038/S41586-019-1102-X  0.359
2019 Hamada T, Yuan C, Yurgelun MB, Perez K, Khalaf N, Morales-Oyarvide V, Babic A, Nowak JA, Rubinson DA, Giannakis M, Ng K, Kraft P, Stampfer MJ, Giovannucci EL, Fuchs CS, et al. Family history of cancer, Ashkenazi Jewish ancestry, and pancreatic cancer risk. British Journal of Cancer. PMID 30867564 DOI: 10.1038/S41416-019-0426-5  0.383
2019 Kosumi K, Hamada T, Zhang S, Liu L, da Silva A, Koh H, Twombly TS, Mima K, Morikawa T, Song M, Nowak JA, Nishihara R, Saltz LB, Niedzwiecki D, Ou FS, ... ... Giannakis M, et al. Prognostic association of PTGS2 (COX-2) over-expression according to BRAF mutation status in colorectal cancer: Results from two prospective cohorts and CALGB 89803 (Alliance) trial. European Journal of Cancer (Oxford, England : 1990). 111: 82-93. PMID 30826660 DOI: 10.1016/J.Ejca.2019.01.022  0.406
2019 Yang W, Liu L, Keum N, Qian ZR, Nowak JA, Hamada T, Song M, Cao Y, Nosho K, Smith-Warner SA, Zhang S, Masugi Y, Ng K, Kosumi K, Ma Y, ... ... Giannakis M, et al. Calcium intake and risk of colorectal cancer according to tumor infiltrating T cells. Cancer Prevention Research (Philadelphia, Pa.). PMID 30760501 DOI: 10.1158/1940-6207.Capr-18-0279  0.386
2019 Tripathi A, Xie W, Flaifel A, Steinharter JA, Stern Gatof E, Jennings RB, Bouchard G, Fleischer J, Chanza NM, Gray C, Mantia C, Wei XX, Giannakis M, McGregor BA, Choueiri TK, et al. Prognostic significance of CD73 expression in localized renal cell carcinoma (RCC). Journal of Clinical Oncology. 37: 4582-4582. DOI: 10.1200/Jco.2019.37.15_Suppl.4582  0.313
2019 Zaidi S, Phipps A, Harrison T, Grasso C, Steinfelder R, Trinh Q, Connolly C, Banbury B, Rafikova A, Hofer P, Brezina S, Giannakis M, Mu XJ, Quist M, Fuchs C, et al. Abstract 1224: Deep targeted tumor sequencing of colorectal cancer cases to study associations of molecular subtypes with clinical, genetic, and lifestyle risk factors Cancer Research. 78: 1224-1224. DOI: 10.1158/1538-7445.Am2018-1224  0.474
2019 Keller RB, Mazor T, Giannakis M, Nowak J, Sholl L, Aguirre A, Bass A, Sethi N, Nagaraja A, Brais L, Reilly E, Cerami E, Wolpin B. Abstract C130: Precision oncology decision support within the Gastrointestinal Cancer Center at Dana-Farber Cancer Institute (GI TARGET) Molecular Cancer Therapeutics. 18. DOI: 10.1158/1535-7163.Targ-19-C130  0.402
2018 Koh H, Hamada T, Song M, Liu L, Cao Y, Nowak JA, da Silva A, Twombly T, Morikawa T, Kim SA, Masugi Y, Kosumi K, Shi Y, Gu M, Li W, ... ... Giannakis M, et al. Physical Activity and Colorectal Cancer Prognosis According to Tumor-Infiltrating T Cells. Jnci Cancer Spectrum. 2: pky058. PMID 31276098 DOI: 10.1093/Jncics/Pky058  0.417
2018 Wasserman I, Lee LH, Ogino S, Marco MR, Wu C, Chen X, Datta J, Sadot E, Szeglin B, Guillem J, Paty PB, Weiser MR, Nash GM, Saltz L, Barlas A, ... ... Giannakis M, et al. SMAD4 loss in colorectal cancer patients correlates with recurrence, loss of immune infiltrate, and chemoresistance. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 30587545 DOI: 10.1158/1078-0432.Ccr-18-1726  0.43
2018 Grasso CS, Giannakis M. Genomic mechanisms of immune evasion in colorectal cancer: from discovery to clinical practice. Oncotarget. 9: 33743-33744. PMID 30333906 DOI: 10.18632/Oncotarget.26105  0.4
2018 Hamada T, Nowak JA, Masugi Y, Drew DA, Song M, Cao Y, Kosumi K, Mima K, Twombly TS, Liu L, Shi Y, da Silva A, Gu M, Li W, Nosho K, ... ... Giannakis M, et al. Smoking and Risk of Colorectal Cancer Sub-Classified by Tumor-Infiltrating T Cells. Journal of the National Cancer Institute. PMID 30312431 DOI: 10.1093/Jnci/Djy137  0.382
2018 Kosumi K, Hamada T, Koh H, Borowsky J, Bullman S, Twombly TS, Nevo D, Masugi Y, Liu L, da Silva A, Chen Y, Du C, Gu M, Li C, Li W, ... ... Giannakis M, et al. The Amount of Bifidobacterium Genus in Colorectal Carcinoma Tissue in Relation to Tumor Characteristics and Clinical Outcome. The American Journal of Pathology. PMID 30243655 DOI: 10.1016/J.Ajpath.2018.08.015  0.484
2018 Hamada T, Zhang X, Mima K, Bullman S, Sukawa Y, Nowak JA, Kosumi K, Masugi Y, Twombly TS, Cao Y, Song M, Liu L, da Silva A, Shi Y, Gu M, ... ... Giannakis M, et al. Fusobacterium nucleatum in Colorectal Cancer Relates to Immune Response Differentially by Tumor Microsatellite Instability Status. Cancer Immunology Research. PMID 30228205 DOI: 10.1158/2326-6066.Cir-18-0174  0.418
2018 Hamada T, Liu L, Nowak JA, Mima K, Cao Y, Ng K, Twombly TS, Song M, Jung S, Dou R, Masugi Y, Kosumi K, Shi Y, da Silva A, Gu M, ... ... Giannakis M, et al. Vitamin D status after colorectal cancer diagnosis and patient survival according to immune response to tumour. European Journal of Cancer (Oxford, England : 1990). 103: 98-107. PMID 30219720 DOI: 10.1016/J.Ejca.2018.07.130  0.329
2018 Hamada T, Soong TR, Masugi Y, Kosumi K, Nowak JA, da Silva A, Mu XJ, Twombly TS, Koh H, Yang J, Song M, Liu L, Gu M, Shi Y, Nosho K, ... ... Giannakis M, et al. TIME (Tumor Immunity in the MicroEnvironment) classification based on tumor (PD-L1) expression status and tumor-infiltrating lymphocytes in colorectal carcinomas. Oncoimmunology. 7: e1442999. PMID 29900052 DOI: 10.1080/2162402X.2018.1442999  0.458
2018 Ogino S, Giannakis M. Immunoscore for (colorectal) cancer precision medicine. Lancet (London, England). PMID 29754776 DOI: 10.1016/S0140-6736(18)30953-X  0.417
2018 Liu L, Tabung FK, Zhang X, Nowak JA, Qian ZR, Hamada T, Nevo D, Bullman S, Mima K, Kosumi K, da Silva A, Song M, Cao Y, Twombly TS, Shi Y, ... ... Giannakis M, et al. Diets That Promote Colon Inflammation Associate With Risk of Colorectal Carcinomas That Contain Fusobacterium nucleatum. Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association. PMID 29702299 DOI: 10.1016/J.Cgh.2018.04.030  0.349
2018 Grasso CS, Giannakis M, Wells DK, Hamada T, Mu XJ, Quist M, Nowak JA, Nishihara R, Qian ZR, Inamura K, Morikawa T, Nosho K, Abril-Rodriguez G, Connolly C, Escuin-Ordinas H, et al. Genetic mechanisms of immune evasion in colorectal cancer. Cancer Discovery. PMID 29510987 DOI: 10.1158/2159-8290.Cd-17-1327  0.475
2018 AlDubayan SH, Giannakis M, Moore ND, Han GC, Reardon B, Hamada T, Mu XJ, Nishihara R, Qian Z, Liu L, Yurgelun MB, Syngal S, Garraway LA, Ogino S, Fuchs CS, et al. Inherited DNA-Repair Defects in Colorectal Cancer. American Journal of Human Genetics. PMID 29478780 DOI: 10.1016/J.Ajhg.2018.01.018  0.434
2018 Ogino S, Nowak JA, Hamada T, Phipps AI, Peters U, Milner DA, Giovannucci EL, Nishihara R, Giannakis M, Garrett WS, Song M. Integrative analysis of exogenous, endogenous, tumour and immune factors for precision medicine. Gut. PMID 29437869 DOI: 10.1136/Gutjnl-2017-315537  0.372
2018 Miao D, Margolis CA, Gao W, Voss MH, Li W, Martini DJ, Norton C, Bossé D, Wankowicz SM, Cullen D, Horak C, Wind-Rotolo M, Tracy A, Giannakis M, Hodi FS, et al. Genomic correlates of response to immune checkpoint therapies in clear cell renal cell carcinoma. Science (New York, N.Y.). PMID 29301960 DOI: 10.1126/Science.Aan5951  0.385
2018 Perez K, Weekes CD, Cleary JM, Abrams TA, Blaszkowsky LS, Enzinger PC, Giannakis M, Goyal L, Meyerhardt JA, Rubinson DA, Yurgelun MB, Stonely D, Raghavan S, Bakir B, Das K, et al. Phase Ib study of gemcitabine, nab-paclitaxel, and ficlatuzumab in patients with advanced pancreatic cancer. Journal of Clinical Oncology. 36: 693-693. DOI: 10.1200/Jco.2020.38.4_Suppl.693  0.318
2018 Tripathi A, Johnston SE, Zhao YD, Hassan O, Thompson LF, Lalani AA, Wei XX, Giannakis M, Signoretti S, Choueiri TK, Harshman LC. CD73 expression in primary and metastatic renal cell carcinoma (RCC). Journal of Clinical Oncology. 36: 643-643. DOI: 10.1200/Jco.2018.36.6_Suppl.643  0.313
2018 Giannakis M, Grasso C, Wells D, Hamada T, Mu XJ, Quist M, Nowak J, Nishihara R, Connolly CM, Shukla S, Grady WM, Wheeler D, Wu CJ, Zaretsky J, Garraway L, et al. Abstract PR03: Genetic mechanisms of immune evasion in colorectal cancer Cancer Immunology Research. 6. DOI: 10.1158/2326-6074.Tumimm17-Pr03  0.507
2018 Rodon J, Argilés G, Connolly RM, Vaishampayan U, Jonge Md, Garralda E, Giannakis M, Smith DC, Dobson JR, McLaughlin M, Seroutou A, Ji Y, Dolan S, Morawiak J, Moody S, et al. Abstract CT175: Biomarker analyses from a phase I study of WNT974, a first-in-class Porcupine inhibitor, in patients (pts) with advanced solid tumors Cancer Research. 78. DOI: 10.1158/1538-7445.Am2018-Ct175  0.44
2018 Yang W, Liu L, Keum N, Qian ZR, Nowak JA, Hamada T, Song M, Cao Y, Nosho K, Smith-Warner SA, Zhang S, Masugi Y, Ng K, Kosumi K, Ma Y, ... ... Giannakis M, et al. Abstract 693: Calcium intake and risk of colorectal cancer according to tumor-infiltrating T cells: Results from two large U.S. prospective cohorts Cancer Research. 78: 693-693. DOI: 10.1158/1538-7445.Am2018-693  0.422
2018 Luo J, Giannakis M, Colditz G, Wang J, Chapman W, Toriola AT, Mito Y, Nishihara R, Nowak J, Fuchs C, Giovannucci E, Chan AT, Bass A, Ogino S, Fields R, et al. Abstract 1228: Comparative genomic analysis of young-onset and late-onset colorectal cancer Cancer Research. 78: 1228-1228. DOI: 10.1158/1538-7445.Am2018-1228  0.387
2018 Grasso C, Giannakis M, Wells D, Wheeler D, Shinbrot E, Zaidi S, Huyghe J, Geybels M, Salipante S, Abril-Rodriguez G, Escuin-Ordinas H, Puig-Saus C, Shin DS, Ogino S, Ribas A, et al. Abstract B011: Immunoediting in untreated mismatch repair deficient colorectal cancer Molecular Cancer Therapeutics. 17. DOI: 10.1158/1535-7163.Targ-17-B011  0.487
2017 Gu M, Nishihara R, Chen Y, Li W, Shi Y, Masugi Y, Hamada T, Kosumi K, Liu L, da Silva A, Nowak JA, Twombly T, Du C, Koh H, Li W, ... ... Giannakis M, et al. Aspirin exerts high anti-cancer activity in PIK3CA-mutant colon cancer cells. Oncotarget. 8: 87379-87389. PMID 29152088 DOI: 10.18632/Oncotarget.20972  0.403
2017 Masugi Y, Nishihara R, Hamada T, Song M, da Silva A, Kosumi K, Gu M, Shi Y, Li W, Liu L, Nevo D, Inamura K, Cao Y, Liao X, Nosho K, ... ... Giannakis M, et al. Tumor PDCD1LG2 (PD-L2) expression and the lymphocytic reaction to colorectal cancer. Cancer Immunology Research. PMID 29038297 DOI: 10.1158/2326-6066.Cir-17-0122  0.414
2017 Zhang X, Choi PS, Francis JM, Gao GF, Campbell JD, Ramachandran A, Mitsuishi Y, Ha G, Shih J, Vazquez F, Tsherniak A, Taylor AM, Zhou J, Wu Z, Berger AC, ... Giannakis M, et al. Somatic super-enhancer duplications and hotspot mutations lead to oncogenic activation of the KLF5 transcription factor. Cancer Discovery. PMID 28963353 DOI: 10.1158/2159-8290.Cd-17-0532  0.456
2017 Hamada T, Cao Y, Qian ZR, Masugi Y, Nowak JA, Yang J, Song M, Mima K, Kosumi K, Liu L, Shi Y, da Silva A, Gu M, Li W, Keum N, ... ... Giannakis M, et al. Aspirin Use and Colorectal Cancer Survival According to Tumor CD274 (Programmed Cell Death 1 Ligand 1) Expression Status. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. JCO2016707547. PMID 28406723 DOI: 10.1200/Jco.2016.70.7547  0.444
2017 Giannakis M, Ng K. To Treat or Not to Treat: Adjuvant Therapy for Stage II Colon Cancer in the Era of Precision Oncology. Journal of Oncology Practice. 13: 242-244. PMID 28399380 DOI: 10.1200/Jop.2017.022103  0.317
2017 Spira A, Yurgelun MB, Alexandrov L, Rao A, Bejar R, Polyak K, Giannakis M, Shilatifard A, Finn OJ, Dhodapkar M, Kay NE, Braggio E, Vilar E, Mazzilli SA, Rebbeck TR, et al. Precancer Atlas to Drive Precision Prevention Trials. Cancer Research. 77: 1510-1541. PMID 28373404 DOI: 10.1158/0008-5472.Can-16-2346  0.435
2017 Ghazani AA, Oliver NM, St Pierre JP, Garofalo A, Rainville IR, Hiller E, Treacy DJ, Rojas-Rudilla V, Wood S, Bair E, Parello M, Huang F, Giannakis M, Wilson FH, Stover EH, et al. Assigning clinical meaning to somatic and germ-line whole-exome sequencing data in a prospective cancer precision medicine study. Genetics in Medicine : Official Journal of the American College of Medical Genetics. PMID 28125075 DOI: 10.1038/Gim.2016.191  0.345
2017 Rohanizadegan M, Aldubayan SH, Giannakis M, Mu XJ, Nishihara R, Qian ZR, Nowak J, Cao Y, Liu L, Song M, Chan AT, Garraway LA, Ogino S, Fuchs CS, Van Allen EM. Clinical actionability of germline testing in patients with limited colorectal polyps. Journal of Clinical Oncology. 35: e13027-e13027. DOI: 10.1200/Jco.2017.35.15_Suppl.E13027  0.409
2017 Giannakis M, Li H, Jin C, Gopal S, Desai K, Horak C, Wind-Rotolo M, Van Allen EM, Clish C, Hodi FS, Garraway LA, Choueiri TK. Metabolomic correlates of response in nivolumab-treated renal cell carcinoma and melanoma patients. Journal of Clinical Oncology. 35: 3036-3036. DOI: 10.1200/Jco.2017.35.15_Suppl.3036  0.315
2017 Aldubayan SH, Giannakis M, Moore N, Mu XJ, Han GC, Nishihara R, Qian ZR, Liu L, Ogino S, Garraway LA, Fuchs CS, Van Allen EM. Enrichment of germline DNA-repair gene mutations in patients with colorectal cancer. Journal of Clinical Oncology. 35: 1500-1500. DOI: 10.1200/Jco.2017.35.15_Suppl.1500  0.407
2017 Nishihara R, Chan AT, Mu JX, Giannakis M, Mima K, Qian ZR, Bullman S, Kostic AD, Huttenhower C, Garrett W, Giovannucci EL, Meyerson M, Garraway LA, Fuchs CS, Ogino S. Abstract PR01:Fusobacterium nucleatumand mutational landscape of colorectal cancer in whole-exome sequencing analysis Cancer Research. 77. DOI: 10.1158/1538-7445.Crc16-Pr01  0.426
2017 Mima K, Hamada T, Nishihara R, Nowak J, Qian ZR, Kosumi K, Giannakis M, Bullman S, Baba H, Huttenhower C, Garrett W, Chan A, Meyerson M, Fuchs C, Ogino S. Abstract 4560: Fusobacterium nucleatum and tumor immunity status according to microsatellite instability in colorectal cancer Cancer Research. 77: 4560-4560. DOI: 10.1158/1538-7445.Am2017-4560  0.461
2017 Zaidi SH, Sun W, Huyghe J, Grasso CS, Trinh Q, Connolly C, French A, Mu J, Giannakis M, Shinbrot E, Borozan I, Quist MJ, Brenner H, Buchanan D, Campbell P, et al. Abstract 1286: Targeted deep sequencing of colorectal tumor tissues to study associations of tumor subtypes with germline genetic, lifestyle, and environmental risk factors Epidemiology. 77: 1286-1286. DOI: 10.1158/1538-7445.Am2017-1286  0.358
2016 Mima K, Cao Y, Chan AT, Qian ZR, Nowak JA, Masugi Y, Shi Y, Song M, da Silva A, Gu M, Li W, Hamada T, Kosumi K, Hanyuda A, Liu L, ... ... Giannakis M, et al. Fusobacterium nucleatum in Colorectal Carcinoma Tissue According to Tumor Location. Clinical and Translational Gastroenterology. 7: e200. PMID 27811909 DOI: 10.1038/Ctg.2016.53  0.378
2016 Giannakis M, Mu XJ, Shukla SA, Qian ZR, Cohen O, Nishihara R, Bahl S, Cao Y, Amin-Mansour A, Yamauchi M, Sukawa Y, Stewart C, Rosenberg M, Mima K, Inamura K, et al. Genomic Correlates of Immune-Cell Infiltrates in Colorectal Carcinoma. Cell Reports. 17: 1206. PMID 27760322 DOI: 10.1016/J.Celrep.2016.10.009  0.362
2016 Garofalo A, Sholl L, Reardon B, Taylor-Weiner A, Amin-Mansour A, Miao D, Liu D, Oliver N, MacConaill L, Ducar M, Rojas-Rudilla V, Giannakis M, Ghazani A, Gray S, Janne P, et al. The impact of tumor profiling approaches and genomic data strategies for cancer precision medicine. Genome Medicine. 8: 79. PMID 27460824 DOI: 10.1186/S13073-016-0333-9  0.376
2016 Gibson WJ, Hoivik EA, Halle MK, Taylor-Weiner A, Cherniack AD, Berg A, Holst F, Zack TI, Werner HM, Staby KM, Rosenberg M, Stefansson IM, Kusonmano K, Chevalier A, Mauland KK, ... ... Giannakis M, et al. The genomic landscape and evolution of endometrial carcinoma progression and abdominopelvic metastasis. Nature Genetics. PMID 27348297 DOI: 10.1038/Ng.3602  0.453
2016 Masugi Y, Nishihara R, Yang J, Mima K, da Silva A, Shi Y, Inamura K, Cao Y, Song M, Nowak JA, Liao X, Nosho K, Chan AT, Giannakis M, Bass AJ, et al. Tumour CD274 (PD-L1) expression and T cells in colorectal cancer. Gut. PMID 27196573 DOI: 10.1136/Gutjnl-2016-311421  0.346
2016 Giannakis M, Mu XJ, Shukla SA, Qian ZR, Cohen O, Nishihara R, Bahl S, Cao Y, Amin-Mansour A, Yamauchi M, Sukawa Y, Stewart C, Rosenberg M, Mima K, Inamura K, et al. Genomic Correlates of Immune-Cell Infiltrates in Colorectal Carcinoma. Cell Reports. PMID 27149842 DOI: 10.1016/J.Celrep.2016.03.075  0.489
2016 Giannakis M, Mu JX, Shukla S, Qian ZR, Cohen O, Nishihara R, Cao Y, Yamauchi M, Sukawa Y, Nosho K, Ng K, Meyerhardt JA, Lawrence M, Gabriel SB, Lander E, et al. Novel driver genes and genomic predictors of immune infiltrates in colorectal cancer. Journal of Clinical Oncology. 34: 557-557. DOI: 10.1200/Jco.2016.34.4_Suppl.557  0.47
2016 Zaidi SH, Grasso C, Mu J, Shinbrot E, Giannakis M, Connolly C, Borozan I, Brenner H, Campbell P, Chan A, Chang-Claude J, Du M, Ferretti V, French A, Fuchs C, et al. Abstract 5221: Linking the molecular profile of colorectal tumors to germline genetic and environmental risk factors Cancer Research. 76: 5221-5221. DOI: 10.1158/1538-7445.Am2016-5221  0.453
2016 Grasso CS, Shinbrot E, Yu M, Liesersen M, Chaisson M, Chan A, Connolly C, Dai J, Du M, Fuchs C, Garraway L, Giannakis M, Harrison T, Hsu L, Huyghe J, et al. Abstract 136: Refining the molecular profile of colorectal tumors to expand prevention and treatment opportunities Cancer Research. 76: 136-136. DOI: 10.1158/1538-7445.Am2016-136  0.444
2015 Mima K, Nishihara R, Nowak J, Kim SA, Song M, Inamura K, Sukawa Y, Masuda A, Yang J, Dou R, Nosho K, Baba H, Giovannucci EL, Bowden M, Loda M, ... Giannakis M, et al. MicroRNA MIR21 and T-cells in Colorectal Cancer. Cancer Immunology Research. PMID 26419959 DOI: 10.1158/2326-6066.Cir-15-0084  0.361
2015 Mima K, Nishihara R, Qian ZR, Cao Y, Sukawa Y, Nowak JA, Yang J, Dou R, Masugi Y, Song M, Kostic AD, Giannakis M, Bullman S, Milner DA, Baba H, et al. Fusobacterium nucleatum in colorectal carcinoma tissue and patient prognosis. Gut. PMID 26311717 DOI: 10.1136/Gutjnl-2015-310101  0.401
2015 Mima K, Sukawa Y, Nishihara R, Qian ZR, Yamauchi M, Inamura K, Kim SA, Masuda A, Nowak JA, Nosho K, Kostic AD, Giannakis M, Watanabe H, Bullman S, Milner DA, et al. Fusobacterium nucleatum and T Cells in Colorectal Carcinoma. Jama Oncology. PMID 26181352 DOI: 10.1001/Jamaoncol.2015.1377  0.421
2015 Van Allen EM, Golay HG, Liu Y, Koyama S, Wong K, Taylor-Weiner A, Giannakis M, Harden M, Rojas-Rudilla V, Chevalier A, Thai T, Lydon C, Mach S, Avila AG, Wong JA, et al. Long-term Benefit of PD-L1 Blockade in Lung Cancer Associated with JAK3 Activation. Cancer Immunology Research. PMID 26014096 DOI: 10.1158/2326-6066.Cir-15-0024  0.349
2015 Giannakis M, Shukla S, Mu JX, Nishihara R, Yamauchi M, Sukawa Y, Qian ZR, Nosho K, Inamura K, Bahl S, Ng K, Chan AT, Meyerhardt JA, Gabriel SB, Lander E, et al. Comprehensive molecular characterization of colorectal cancer reveals genomic predictors of immune cell infiltrates. Journal of Clinical Oncology. 33: 3505-3505. DOI: 10.1200/Jco.2015.33.15_Suppl.3505  0.466
2014 Giannakis M, Hodis E, Jasmine Mu X, Yamauchi M, Rosenbluh J, Cibulskis K, Saksena G, Lawrence MS, Qian ZR, Nishihara R, Van Allen EM, Hahn WC, Gabriel SB, Lander ES, Getz G, et al. RNF43 is frequently mutated in colorectal and endometrial cancers. Nature Genetics. 46: 1264-6. PMID 25344691 DOI: 10.1038/Ng.3127  0.416
2009 Giannakis M, Bäckhed HK, Chen SL, Faith JJ, Wu M, Guruge JL, Engstrand L, Gordon JI. Response of gastric epithelial progenitors to Helicobacter pylori Isolates obtained from Swedish patients with chronic atrophic gastritis. The Journal of Biological Chemistry. 284: 30383-94. PMID 19723631 DOI: 10.1074/Jbc.M109.052738  0.478
2008 Giannakis M, Chen SL, Karam SM, Engstrand L, Gordon JI. Helicobacter pylori evolution during progression from chronic atrophic gastritis to gastric cancer and its impact on gastric stem cells. Proceedings of the National Academy of Sciences of the United States of America. 105: 4358-63. PMID 18332421 DOI: 10.1073/Pnas.0800668105  0.536
2006 Oh JD, Kling-Bäckhed H, Giannakis M, Xu J, Fulton RS, Fulton LA, Cordum HS, Wang C, Elliott G, Edwards J, Mardis ER, Engstrand LG, Gordon JI. The complete genome sequence of a chronic atrophic gastritis Helicobacter pylori strain: evolution during disease progression. Proceedings of the National Academy of Sciences of the United States of America. 103: 9999-10004. PMID 16788065 DOI: 10.1073/Pnas.0603784103  0.517
2006 Giannakis M, Stappenbeck TS, Mills JC, Leip DG, Lovett M, Clifton SW, Ippolito JE, Glasscock JI, Arumugam M, Brent MR, Gordon JI. Molecular properties of adult mouse gastric and intestinal epithelial progenitors in their niches. The Journal of Biological Chemistry. 281: 11292-300. PMID 16464855 DOI: 10.1074/Jbc.M512118200  0.662
2006 Oh JD, Kling-Bäckhed H, Giannakis M, Engstrand LG, Gordon JI. Interactions between gastric epithelial stem cells and Helicobacter pylori in the setting of chronic atrophic gastritis. Current Opinion in Microbiology. 9: 21-7. PMID 16406776 DOI: 10.1016/J.Mib.2005.12.013  0.494
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