| Year |
Citation |
Score |
| 2020 |
Konstantinidou M, Magari F, Sutanto F, Haupenthal J, Jumde VR, Ünver MY, Heine A, Camacho CJ, Hirsch AKH, Klebe G, Dömling A. Rapid Discovery of Aspartyl Protease Inhibitors Using an Anchoring Approach. Chemmedchem. PMID 32187447 DOI: 10.1002/Cmdc.202000024 |
0.359 |
|
| 2020 |
Vakirlis N, Acar O, Hsu B, Castilho Coelho N, Van Oss SB, Wacholder A, Medetgul-Ernar K, Bowman RW, Hines CP, Iannotta J, Parikh SB, McLysaght A, Camacho CJ, O'Donnell AF, Ideker T, et al. De novo emergence of adaptive membrane proteins from thymine-rich genomic sequences. Nature Communications. 11: 781. PMID 32034123 DOI: 10.1038/S41467-020-14500-Z |
0.306 |
|
| 2019 |
Dorman HR, Close D, Wingert BM, Camacho CJ, Johnston PA, Smithgall TE. Discovery of Non-peptide Small Molecule Allosteric Modulators of the Src-family Kinase, Hck. Frontiers in Chemistry. 7: 822. PMID 31850311 DOI: 10.3389/Fchem.2019.00822 |
0.358 |
|
| 2019 |
Wierbowski SD, Wingert BM, Zheng J, Camacho CJ. Cross-docking benchmark for automated pose and ranking prediction of ligand binding. Protein Science : a Publication of the Protein Society. PMID 31721338 DOI: 10.1002/Pro.3784 |
0.367 |
|
| 2019 |
Shao H, Wingert B, Weins A, Pollak MR, Camacho C, Wells A. Focal segmental glomerulosclerosis ACTN4 mutants binding to actin: regulation by phosphomimetic mutations. Scientific Reports. 9: 15517. PMID 31664084 DOI: 10.1038/S41598-019-51825-2 |
0.322 |
|
| 2019 |
Yeh CY, Ye Z, Moutal A, Gaur S, Henton AM, Kouvaros S, Saloman JL, Hartnett-Scott KA, Tzounopoulos T, Khanna R, Aizenman E, Camacho CJ. Defining the Kv2.1-syntaxin molecular interaction identifies a first-in-class small molecule neuroprotectant. Proceedings of the National Academy of Sciences of the United States of America. PMID 31308225 DOI: 10.1073/Pnas.1903401116 |
0.303 |
|
| 2018 |
Pabon NA, Xia Y, Estabrooks SK, Ye Z, Herbrand AK, Süß E, Biondi RM, Assimon VA, Gestwicki JE, Brodsky JL, Camacho CJ, Bar-Joseph Z. Predicting protein targets for drug-like compounds using transcriptomics. Plos Computational Biology. 14: e1006651. PMID 30532261 DOI: 10.1371/Journal.Pcbi.1006651 |
0.349 |
|
| 2018 |
Pulugulla SH, Workman R, Rutter NW, Yang Z, Adamik J, Lupish B, Macar DA, El Abdouni S, Esposito EX, Galson DL, Camacho CJ, Madura JD, Auron PE. A combined computational and experimental approach reveals the structure of a C/EBPβ:Spi-1 interaction required for gene transcription. The Journal of Biological Chemistry. PMID 30355733 DOI: 10.1074/Jbc.Ra118.005627 |
0.362 |
|
| 2018 |
Wingert BM, Camacho CJ. Improving small molecule virtual screening strategies for the next generation of therapeutics. Current Opinion in Chemical Biology. 44: 87-92. PMID 29920436 DOI: 10.1016/J.Cbpa.2018.06.006 |
0.338 |
|
| 2018 |
Skoko J, Asan A, Woodcock C, Cao J, Gaboriau D, Paulsen C, Attar M, Wingert B, Woodcock S, Schulte J, Ma H, Camacho C, Liu Y, Morrison C, Carroll K, et al. Loss of PRDX1 increases RAD51 Cys319 oxidation and decreases homologous recombination Free Radical Biology and Medicine. 128: S73-S74. DOI: 10.1016/J.Freeradbiomed.2018.10.159 |
0.302 |
|
| 2017 |
Koes DR, Dömling A, Camacho CJ. AnchorQuery: Rapid online virtual screening for small-molecule protein-protein interaction inhibitors. Protein Science : a Publication of the Protein Society. PMID 28921842 DOI: 10.1002/Pro.3303 |
0.374 |
|
| 2017 |
Wingert BM, Oerlemans R, Camacho CJ. Optimal affinity ranking for automated virtual screening validated in prospective D3R grand challenges. Journal of Computer-Aided Molecular Design. PMID 28918599 DOI: 10.1007/S10822-017-0065-Y |
0.33 |
|
| 2017 |
Ye Z, Needham PG, Estabrooks SK, Whitaker SK, Garcia BL, Misra S, Brodsky JL, Camacho CJ. Symmetry breaking during homodimeric assembly activates an E3 ubiquitin ligase. Scientific Reports. 7: 1789. PMID 28496195 DOI: 10.1038/S41598-017-01880-4 |
0.362 |
|
| 2017 |
Pabon NA, Camacho CJ. Probing protein flexibility reveals a mechanism for selective promiscuity. Elife. 6. PMID 28432789 DOI: 10.7554/Elife.22889 |
0.344 |
|
| 2017 |
Cascio S, Faylo J, Sriram R, Vlad A, Camacho C, Finn OJ. Abstract 4126: Validation of hypoglycosylated MUC1-CIN85 protein-protein interaction as a new therapeutic target for prevention of cancer invasion and metastasis Cancer Research. 77: 4126-4126. DOI: 10.1158/1538-7445.Am2017-4126 |
0.318 |
|
| 2016 |
Surmiak E, Neochoritis CG, Musielak B, Twarda-Clapa A, Kurpiewska K, Dubin G, Camacho C, Holak TA, Dömling A. Rational design and synthesis of 1,5-disubstituted tetrazoles as potent inhibitors of the MDM2-p53 interaction. European Journal of Medicinal Chemistry. 126: 384-407. PMID 27907876 DOI: 10.1016/J.Ejmech.2016.11.029 |
0.372 |
|
| 2016 |
Ye Z, Baumgartner MP, Wingert BM, Camacho CJ. Optimal strategies for virtual screening of induced-fit and flexible target in the 2015 D3R Grand Challenge. Journal of Computer-Aided Molecular Design. PMID 27573981 DOI: 10.1007/S10822-016-9941-0 |
0.383 |
|
| 2016 |
Travers TS, Harlow L, Rosas IO, Gochuico BR, Mikuls TR, Bhattacharya SK, Camacho CJ, Ascherman DP. Extensive Citrullination Promotes Immunogenicity of HSP90 through Protein Unfolding and Exposure of Cryptic Epitopes. Journal of Immunology (Baltimore, Md. : 1950). PMID 27448590 DOI: 10.4049/Jimmunol.1600162 |
0.336 |
|
| 2016 |
Tejero J, Kapralov AA, Baumgartner MP, Sparacino-Watkins CE, Anthonymutu TS, Vlasova II, Camacho CJ, Gladwin MT, Bayir H, Kagan VE. Peroxidase activation of cytoglobin by anionic phospholipids: Mechanisms and consequences. Biochimica Et Biophysica Acta. PMID 26928591 DOI: 10.1016/J.Bbalip.2016.02.022 |
0.324 |
|
| 2015 |
Kroon E, Schulze JO, Süß E, Camacho CJ, Biondi RM, Dömling A. Discovery of a Potent Allosteric Kinase Modulator by Combining Computational and Synthetic Methods. Angewandte Chemie (International Ed. in English). PMID 26385475 DOI: 10.1002/Anie.201506310 |
0.333 |
|
| 2015 |
Abdelraheem EM, Camacho CJ, Dömling A. Focusing on shared subpockets - new developments in fragment-based drug discovery. Expert Opinion On Drug Discovery. 1-9. PMID 26296101 DOI: 10.1517/17460441.2015.1080684 |
0.364 |
|
| 2015 |
Koes DR, Pabon NA, Deng X, Phillips MA, Camacho CJ. A Teach-Discover-Treat Application of ZincPharmer: An Online Interactive Pharmacophore Modeling and Virtual Screening Tool. Plos One. 10: e0134697. PMID 26258606 DOI: 10.1371/Journal.Pone.0134697 |
0.34 |
|
| 2015 |
Baumgartner MP, Camacho CJ. Choosing the Optimal Rigid Receptor for Docking and Scoring in the CSAR 2013/2014 Experiment. Journal of Chemical Information and Modeling. PMID 26222931 DOI: 10.1021/Acs.Jcim.5B00338 |
0.366 |
|
| 2015 |
Grover P, Shi H, Baumgartner M, Camacho CJ, Smithgall TE. Fluorescence Polarization Screening Assays for Small Molecule Allosteric Modulators of ABL Kinase Function. Plos One. 10: e0133590. PMID 26222440 DOI: 10.1371/Journal.Pone.0133590 |
0.356 |
|
| 2015 |
Kwun HJ, Shuda M, Camacho CJ, Gamper AM, Thant M, Chang Y, Moore PS. Restricted protein phosphatase 2A targeting by Merkel cell polyomavirus small T antigen. Journal of Virology. 89: 4191-200. PMID 25631078 DOI: 10.1128/Jvi.00157-15 |
0.368 |
|
| 2015 |
Grover P, Shi H, Baumgartner M, Close D, Johnston PA, Camacho CJ, Smithgall TE. Abstract B132: Discovery of small molecule allosteric modulators of Abl kinase activity and function Molecular Cancer Therapeutics. 14. DOI: 10.1158/1535-7163.Targ-15-B132 |
0.357 |
|
| 2014 |
Koes DR, Camacho CJ. Shape-based virtual screening with volumetric aligned molecular shapes. Journal of Computational Chemistry. 35: 1824-34. PMID 25049193 DOI: 10.1002/Jcc.23690 |
0.304 |
|
| 2014 |
Cascio S, Sciurba J, Hughey R, Camacho C, Finn O. Abstract 3151: Muc1/Cin85 complex is a new molecular target for control of cancer invasion and metastasis Cancer Research. 74: 3151-3151. DOI: 10.1158/1538-7445.Am2014-3151 |
0.34 |
|
| 2013 |
Travers T, Shao H, Wells A, Camacho CJ. Modeling the assembly of the multiple domains of α-actinin-4 and its role in actin cross-linking. Biophysical Journal. 104: 705-15. PMID 23442921 DOI: 10.1016/J.Bpj.2012.12.003 |
0.369 |
|
| 2013 |
Travers T, Shao H, Wells A, Camacho CJ. Modeling of Multi-Domain Assemblies in α-Actinin-4 Reveals How External Cues Regulate its Binding to Actin Biophysical Journal. 104: 647a. DOI: 10.1016/J.Bpj.2012.11.3573 |
0.374 |
|
| 2012 |
Koes DR, Camacho CJ. ZINCPharmer: pharmacophore search of the ZINC database. Nucleic Acids Research. 40: W409-14. PMID 22553363 DOI: 10.1093/Nar/Gks378 |
0.311 |
|
| 2012 |
Koes DR, Camacho CJ. PocketQuery: protein-protein interaction inhibitor starting points from protein-protein interaction structure. Nucleic Acids Research. 40: W387-92. PMID 22523085 DOI: 10.1093/Nar/Gks336 |
0.406 |
|
| 2012 |
Koes D, Khoury K, Huang Y, Wang W, Bista M, Popowicz GM, Wolf S, Holak TA, Dömling A, Camacho CJ. Enabling large-scale design, synthesis and validation of small molecule protein-protein antagonists. Plos One. 7: e32839. PMID 22427896 DOI: 10.1371/Journal.Pone.0032839 |
0.392 |
|
| 2012 |
Koes DR, Camacho CJ. Small-molecule inhibitor starting points learned from protein-protein interaction inhibitor structure. Bioinformatics (Oxford, England). 28: 784-91. PMID 22210869 DOI: 10.1093/Bioinformatics/Btr717 |
0.388 |
|
| 2011 |
Fleishman SJ, Whitehead TA, Strauch EM, Corn JE, Qin S, Zhou HX, Mitchell JC, Demerdash ON, Takeda-Shitaka M, Terashi G, Moal IH, Li X, Bates PA, Zacharias M, Park H, ... ... Camacho CJ, et al. Community-wide assessment of protein-interface modeling suggests improvements to design methodology. Journal of Molecular Biology. 414: 289-302. PMID 22001016 DOI: 10.1016/J.Jmb.2011.09.031 |
0.549 |
|
| 2011 |
Camacho CJ. Novel Polarizable Empirical Code for Accurate Prediction of Protein-DNA Interactions Biophysical Journal. 100: 70a. DOI: 10.1016/J.Bpj.2010.12.580 |
0.42 |
|
| 2010 |
Bueno M, Temiz NA, Camacho CJ. Novel modulation factor quantifies the role of water molecules in protein interactions. Proteins. 78: 3226-34. PMID 20665475 DOI: 10.1002/Prot.22805 |
0.662 |
|
| 2010 |
Meireles LM, Dömling AS, Camacho CJ. ANCHOR: a web server and database for analysis of protein-protein interaction binding pockets for drug discovery. Nucleic Acids Research. 38: W407-11. PMID 20525787 DOI: 10.1093/Nar/Gkq502 |
0.423 |
|
| 2010 |
Temiz AN, Benos PV, Camacho CJ. Electrostatic hot spot on DNA-binding domains mediates phosphate desolvation and the pre-organization of specificity determinant side chains. Nucleic Acids Research. 38: 2134-44. PMID 20047959 DOI: 10.1093/Nar/Gkp1132 |
0.361 |
|
| 2010 |
Temiz NA, Trapp A, Prokopyev OA, Camacho CJ. Optimization of minimum set of protein-DNA interactions: a quasi exact solution with minimum over-fitting. Bioinformatics (Oxford, England). 26: 319-25. PMID 19965883 DOI: 10.1093/Bioinformatics/Btp664 |
0.657 |
|
| 2010 |
Zhang W, Camacho CJ, Eyal E. Predicting the Interactions between PDZ Adapter Domains and Disordered Peptides Biophysical Journal. 98: 429a. DOI: 10.1016/J.Bpj.2009.12.2324 |
0.389 |
|
| 2010 |
Liu J, James FR, Camacho CJ. On the Origins of Intrinsically Disordered Proteins Biophysical Journal. 98: 257a. DOI: 10.1016/J.Bpj.2009.12.1399 |
0.402 |
|
| 2009 |
Liu J, Faeder JR, Camacho CJ. Toward a quantitative theory of intrinsically disordered proteins and their function. Proceedings of the National Academy of Sciences of the United States of America. 106: 19819-23. PMID 19903882 DOI: 10.1073/Pnas.0907710106 |
0.395 |
|
| 2009 |
Temiz NA, Camacho CJ. Experimentally based contact energies decode interactions responsible for protein-DNA affinity and the role of molecular waters at the binding interface. Nucleic Acids Research. 37: 4076-88. PMID 19429892 DOI: 10.1093/Nar/Gkp289 |
0.688 |
|
| 2007 |
Bueno M, Camacho CJ. Acidic groups docked to well defined wetted pockets at the core of the binding interface: a tale of scoring and missing protein interactions in CAPRI. Proteins. 69: 786-92. PMID 17803211 DOI: 10.1002/Prot.21722 |
0.387 |
|
| 2007 |
Champ PC, Camacho CJ. FastContact: a free energy scoring tool for protein-protein complex structures. Nucleic Acids Research. 35: W556-60. PMID 17537824 DOI: 10.1093/Nar/Gkm326 |
0.409 |
|
| 2007 |
Bueno M, Camacho CJ, Sancho J. SIMPLE estimate of the free energy change due to aliphatic mutations: superior predictions based on first principles. Proteins. 68: 850-62. PMID 17523191 DOI: 10.1002/Prot.21453 |
0.359 |
|
| 2007 |
Iyer AK, Tran KT, Borysenko CW, Cascio M, Camacho CJ, Blair HC, Bahar I, Wells A. Tenascin cytotactin epidermal growth factor-like repeat binds epidermal growth factor receptor with low affinity. Journal of Cellular Physiology. 211: 748-58. PMID 17311283 DOI: 10.1002/Jcp.20986 |
0.31 |
|
| 2006 |
Camacho CJ, Ma H, Champ PC. Scoring a diverse set of high-quality docked conformations: a metascore based on electrostatic and desolvation interactions. Proteins. 63: 868-77. PMID 16506242 DOI: 10.1002/Prot.20932 |
0.434 |
|
| 2005 |
Comeau SR, Vajda S, Camacho CJ. Performance of the first protein docking server ClusPro in CAPRI rounds 3-5. Proteins. 60: 239-44. PMID 15981265 DOI: 10.1002/Prot.20564 |
0.425 |
|
| 2005 |
Camacho CJ. Modeling side-chains using molecular dynamics improve recognition of binding region in CAPRI targets. Proteins. 60: 245-51. PMID 15981253 DOI: 10.1002/Prot.20565 |
0.428 |
|
| 2005 |
Kozakov D, Clodfelter KH, Vajda S, Camacho CJ. Optimal clustering for detecting near-native conformations in protein docking. Biophysical Journal. 89: 867-75. PMID 15908573 DOI: 10.1529/Biophysj.104.058768 |
0.327 |
|
| 2005 |
Comeau SR, Camacho CJ. Predicting oligomeric assemblies: N-mers a primer. Journal of Structural Biology. 150: 233-44. PMID 15890272 DOI: 10.1016/J.Jsb.2005.03.006 |
0.401 |
|
| 2005 |
Camacho CJ, Zhang C. FastContact: rapid estimate of contact and binding free energies. Bioinformatics (Oxford, England). 21: 2534-6. PMID 15713734 DOI: 10.1093/Bioinformatics/Bti322 |
0.443 |
|
| 2004 |
Rajamani D, Thiel S, Vajda S, Camacho CJ. Anchor residues in protein-protein interactions. Proceedings of the National Academy of Sciences of the United States of America. 101: 11287-92. PMID 15269345 DOI: 10.1073/Pnas.0401942101 |
0.436 |
|
| 2004 |
Comeau SR, Gatchell DW, Vajda S, Camacho CJ. ClusPro: a fully automated algorithm for protein-protein docking. Nucleic Acids Research. 32: W96-9. PMID 15215358 DOI: 10.1093/Nar/Gkh354 |
0.34 |
|
| 2004 |
Prasad JC, Vajda S, Camacho CJ. Consensus alignment server for reliable comparative modeling with distant templates. Nucleic Acids Research. 32: W50-4. PMID 15215349 DOI: 10.1093/Nar/Gkh456 |
0.338 |
|
| 2004 |
Vajda S, Camacho CJ. Protein-protein docking: is the glass half-full or half-empty? Trends in Biotechnology. 22: 110-6. PMID 15036860 DOI: 10.1016/J.Tibtech.2004.01.006 |
0.395 |
|
| 2004 |
Comeau SR, Gatchell DW, Vajda S, Camacho CJ. ClusPro: an automated docking and discrimination method for the prediction of protein complexes. Bioinformatics (Oxford, England). 20: 45-50. PMID 14693807 DOI: 10.1093/Bioinformatics/Btg371 |
0.397 |
|
| 2003 |
Prasad JC, Comeau SR, Vajda S, Camacho CJ. Consensus alignment for reliable framework prediction in homology modeling. Bioinformatics (Oxford, England). 19: 1682-91. PMID 12967965 DOI: 10.1093/Bioinformatics/Btg211 |
0.303 |
|
| 2003 |
Camacho CJ, Gatchell DW. Successful discrimination of protein interactions. Proteins. 52: 92-7. PMID 12784373 DOI: 10.1002/Prot.10394 |
0.369 |
|
| 2002 |
Camacho CJ, Vajda S. Protein-protein association kinetics and protein docking. Current Opinion in Structural Biology. 12: 36-40. PMID 11839487 DOI: 10.1016/S0959-440X(02)00286-5 |
0.4 |
|
| 2001 |
Camacho CJ, Vajda S. Protein docking along smooth association pathways. Proceedings of the National Academy of Sciences of the United States of America. 98: 10636-41. PMID 11517309 DOI: 10.1073/Pnas.181147798 |
0.41 |
|
| 2001 |
Kimura SR, Brower RC, Vajda S, Camacho CJ. Dynamical view of the positions of key side chains in protein-protein recognition Biophysical Journal. 80: 635-642. PMID 11159432 DOI: 10.1016/S0006-3495(01)76044-4 |
0.453 |
|
| 2000 |
Yanai I, Camacho CJ, DeLisi C. Predictions of gene family distributions in microbial genomes: evolution by gene duplication and modification. Physical Review Letters. 85: 2641-4. PMID 10978127 DOI: 10.1103/Physrevlett.85.2641 |
0.627 |
|
| 2000 |
Camacho CJ, Gatchell DW, Kimura SR, Vajda S. Scoring docked conformations generated by rigid-body protein-protein docking. Proteins. 40: 525-37. PMID 10861944 DOI: 10.1002/1097-0134(20000815)40:3<525::Aid-Prot190>3.0.Co;2-F |
0.437 |
|
| 2000 |
Camacho CJ, Kimura SR, DeLisi C, Vajda S. Kinetics of desolvation-mediated protein-protein binding. Biophysical Journal. 78: 1094-105. PMID 10692300 DOI: 10.1016/S0006-3495(00)76668-9 |
0.618 |
|
| 2000 |
Dennis S, Camacho CJ, Vajda S. Continuum electrostatic analysis of preferred solvation sites around proteins in solution. Proteins. 38: 176-88. PMID 10656264 DOI: 10.1002/(Sici)1097-0134(20000201)38:2<176::Aid-Prot6>3.0.Co;2-O |
0.341 |
|
| 1999 |
Camacho CJ, Weng Z, Vajda S, DeLisi C. Free energy landscapes of encounter complexes in protein-protein association. Biophysical Journal. 76: 1166-78. PMID 10049302 DOI: 10.1016/S0006-3495(99)77281-4 |
0.655 |
|
| 1996 |
Camacho CJ. Entropic Barriers, Frustration, and Order: Basic Ingredients in Protein Folding. Physical Review Letters. 77: 2324-2327. PMID 10061915 DOI: 10.1103/Physrevlett.77.2324 |
0.34 |
|
| 1996 |
Camacho CJ, Thirumalai D. Denaturants can accelerate folding rates in a class of globular proteins. Protein Science : a Publication of the Protein Society. 5: 1826-32. PMID 8880906 DOI: 10.1002/Pro.5560050908 |
0.342 |
|
| 1996 |
Camacho CJ, Thirumalai D. A criterion that determines fast folding of proteins: A model study Europhysics Letters. 35: 627-632. DOI: 10.1209/Epl/I1996-00162-1 |
0.369 |
|
| 1995 |
Camacho CJ, Thirumalai D. Modeling the role of disulfide bonds in protein folding: entropic barriers and pathways. Proteins. 22: 27-40. PMID 7675784 DOI: 10.1002/Prot.340220105 |
0.343 |
|
| 1995 |
Camacho CJ, Thirumalai D. Theoretical predictions of folding pathways by using the proximity rule, with applications to bovine pancreatic trypsin inhibitor. Proceedings of the National Academy of Sciences of the United States of America. 92: 1277-81. PMID 7533290 DOI: 10.1073/Pnas.92.5.1277 |
0.304 |
|
| 1993 |
Camacho CJ, Thirumalai D. Kinetics and thermodynamics of folding in model proteins. Proceedings of the National Academy of Sciences of the United States of America. 90: 6369-72. PMID 8327519 DOI: 10.1073/Pnas.90.13.6369 |
0.32 |
|
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