| Year |
Citation |
Score |
| 2023 |
Deal PE, Lee H, Mondal A, Lolicato M, de Mendonca PRF, Black H, El-Hilali X, Bryant C, Isacoff EY, Renslo AR, Minor DL. Development of covalent chemogenetic K channel activators. Biorxiv : the Preprint Server For Biology. PMID 37905049 DOI: 10.1101/2023.10.15.561774 |
0.724 |
|
| 2023 |
Gonciarz RL, Jiang H, Tram L, Hugelshofer CL, Ekpenyong O, Knemeyer I, Aron AT, Chang CJ, Flygare JA, Collisson EA, Renslo AR. In vivo bioluminescence imaging of labile iron in xenograft models and liver using FeAL-1, an iron-activatable form of D-luciferin. Cell Chemical Biology. PMID 37820725 DOI: 10.1016/j.chembiol.2023.09.006 |
0.79 |
|
| 2023 |
Togo T, Tram L, Denton LG, ElHilali-Pollard X, Gu J, Jiang J, Liu C, Zhao Y, Zhao Y, Zheng Y, Zheng Y, Yang J, Fan P, Arkin MR, Härmä H, ... ... Renslo AR, et al. Systematic Study of Heteroarene Stacking Using a Congeneric Set of Molecular Glues for Procaspase-6. Journal of Medicinal Chemistry. PMID 37406165 DOI: 10.1021/acs.jmedchem.3c00590 |
0.746 |
|
| 2023 |
Fink EA, Bardine C, Gahbauer S, Singh I, Detomasi T, White K, Gu S, Wan X, Chen J, Ary B, Glenn I, O'Connell J, O'Donnell H, Fajtová P, Lyu J, ... ... Renslo AR, et al. Large library docking for novel SARS-CoV-2 main protease non-covalent and covalent inhibitors. Protein Science : a Publication of the Protein Society. e4712. PMID 37354015 DOI: 10.1002/pro.4712 |
0.551 |
|
| 2023 |
Blank BR, Gut J, Rosenthal PJ, Renslo AR. Artefenomel Regioisomer RLA-3107 Is a Promising Lead for the Discovery of Next-Generation Endoperoxide Antimalarials. Acs Medicinal Chemistry Letters. 14: 493-498. PMID 37077383 DOI: 10.1021/acsmedchemlett.3c00039 |
0.781 |
|
| 2023 |
Admasu TD, Kim K, Rae M, Avelar R, Gonciarz RL, Rebbaa A, Pedro de Magalhães J, Renslo AR, Stolzing A, Sharma A. Selective ablation of primary and paracrine senescent cells by targeting iron dyshomeostasis. Cell Reports. 42: 112058. PMID 36753419 DOI: 10.1016/j.celrep.2023.112058 |
0.788 |
|
| 2023 |
Gonciarz RL, Sakhamuri S, Hooshdaran N, Kumar G, Kim H, Evans MJ, Renslo AR. Elevated labile iron in castration-resistant prostate cancer is targetable with ferrous iron-activatable antiandrogen therapy. European Journal of Medicinal Chemistry. 249: 115110. PMID 36708680 DOI: 10.1016/j.ejmech.2023.115110 |
0.817 |
|
| 2022 |
Sacco MD, Defrees K, Zhang X, Lawless W, Nwanochie E, Balsizer A, Darch SE, Renslo AR, Chen Y. Structure-Based Ligand Design Targeting LpxA in Lipid A Biosynthesis. Acs Infectious Diseases. PMID 35653508 DOI: 10.1021/acsinfecdis.1c00650 |
0.79 |
|
| 2022 |
Jiang H, Muir RK, Gonciarz RL, Olshen AB, Yeh I, Hann BC, Zhao N, Wang YH, Behr SC, Korkola JE, Evans MJ, Collisson EA, Renslo AR. Ferrous iron-activatable drug conjugate achieves potent MAPK blockade in KRAS-driven tumors. The Journal of Experimental Medicine. 219. PMID 35262628 DOI: 10.1084/jem.20210739 |
0.8 |
|
| 2021 |
Chen J, Gonciarz RL, Renslo AR. Correction: Expanded scope of Griesbaum co-ozonolysis for the preparation of structurally diverse sensors of ferrous iron. Rsc Advances. 11: 36625. PMID 35503277 DOI: 10.1039/d1ra90167b |
0.784 |
|
| 2021 |
Chen J, Gonciarz RL, Renslo AR. Expanded scope of Griesbaum co-ozonolysis for the preparation of structurally diverse sensors of ferrous iron. Rsc Advances. 11: 34338-34342. PMID 35497286 DOI: 10.1039/d1ra05932g |
0.805 |
|
| 2021 |
Kemp MT, Nichols DA, Zhang X, Defrees K, Na I, Renslo AR, Chen Y. Mutation of the conserved Asp-Asp pair impairs the structure, function, and inhibition of CTX-M Class A β-lactamase. Febs Letters. PMID 34704263 DOI: 10.1002/1873-3468.14215 |
0.77 |
|
| 2021 |
Gonciarz RL, Renslo AR. Emerging role of ferrous iron in bacterial growth and host-pathogen interaction: New tools for chemical (micro)biology and antibacterial therapy. Current Opinion in Chemical Biology. 61: 170-178. PMID 33714882 DOI: 10.1016/j.cbpa.2021.01.015 |
0.806 |
|
| 2020 |
Gonciarz RL, Collisson EA, Renslo AR. Ferrous Iron-Dependent Pharmacology. Trends in Pharmacological Sciences. PMID 33261861 DOI: 10.1016/j.tips.2020.11.003 |
0.815 |
|
| 2020 |
Zhao N, Huang Y, Wang YH, Muir RK, Chen YC, Hooshdaran N, Wei J, Viswanath P, Seo Y, Ruggero D, Renslo AR, Evans MJ. Ferronostics: Measuring Tumoral Ferrous Iron with PET to Predict Sensitivity to Iron-Targeted Cancer Therapies. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. PMID 33246980 DOI: 10.2967/jnumed.120.252460 |
0.795 |
|
| 2020 |
Chen YC, Oses-Prieto JA, Pope LE, Burlingame AL, Dixon SJ, Renslo AR. Reactivity-Based Probe of the Iron(II)-Dependent Interactome Identifies New Cellular Modulators of Ferroptosis. Journal of the American Chemical Society. PMID 33124817 DOI: 10.1021/jacs.0c06709 |
0.67 |
|
| 2020 |
Blank B, Gonciarz R, Talukder P, Gut J, Legac J, Rosenthal PJ, Renslo AR. Antimalarial Trioxolanes with Superior Drug-Like Properties and In Vivo Efficacy. Acs Infectious Diseases. PMID 32369341 DOI: 10.1021/Acsinfecdis.0C00064 |
0.773 |
|
| 2020 |
Bashore C, Jaishankar P, Skelton NJ, Fuhrmann J, Hearn BR, Liu PS, Renslo AR, Dueber EC. Cyanopyrrolidine Inhibitors of Ubiquitin Specific Protease 7 Mediate Desulfhydration of the Active-Site Cysteine. Acs Chemical Biology. PMID 32302100 DOI: 10.1021/Acschembio.0C00031 |
0.33 |
|
| 2020 |
Huff TC, Camarena V, Sant DW, Wilkes Z, Van Booven D, Aron AT, Muir RK, Renslo AR, Chang CJ, Monje PV, Wang G. Oscillatory cAMP signaling rapidly alters H3K4 methylation. Life Science Alliance. 3. PMID 31882444 DOI: 10.26508/lsa.201900529 |
0.763 |
|
| 2020 |
Jiang H, Muir R, Renslo A, Collisson E. Abstract 6419: Novel ferrous iron-dependent prodrug strategy for KRAS-driven pancreatic cancer: The preclinic efficacy and safety test Cancer Research. 80: 6419-6419. DOI: 10.1158/1538-7445.Am2020-6419 |
0.801 |
|
| 2019 |
DeFrees K, Kemp MT, ElHilali-Pollard X, Zhang X, Mohamed A, Chen Y, Renslo AR. An Empirical Study of Amide-Heteroarene π-Stacking Interactions Using Reversible Inhibitors of a Bacterial Serine Hydrolase. Organic Chemistry Frontiers : An International Journal of Organic Chemistry. 6: 1749-1756. PMID 32774871 DOI: 10.1039/C9Qo00342H |
0.786 |
|
| 2019 |
Pemberton OA, Jaishankar P, Akhtar A, Adams JL, Shaw LN, Renslo AR, Chen Y. Heteroaryl phosphonates as non-covalent inhibitors of both serine and metallo-carbapenemases. Journal of Medicinal Chemistry. PMID 31483651 DOI: 10.1021/Acs.Jmedchem.9B00728 |
0.343 |
|
| 2019 |
Blank B, Talukder P, Muir R, Green E, Skaar EP, Renslo AR. Targeting Mobilization of Ferrous Iron in Pseudomonas aeruginosa Infection with an Iron(II)-Caged LpxC Inhibitor. Acs Infectious Diseases. PMID 31140267 DOI: 10.1021/Acsinfecdis.9B00057 |
0.797 |
|
| 2019 |
Muir RK, Zhao N, Wei J, Wang YH, Moroz A, Huang Y, Chen YC, Sriram R, Kurhanewicz J, Ruggero D, Renslo AR, Evans MJ. Measuring Dynamic Changes in the Labile Iron Pool in Vivo with a Reactivity-Based Probe for Positron Emission Tomography. Acs Central Science. 5: 727-736. PMID 31041393 DOI: 10.1021/Acscentsci.9B00240 |
0.806 |
|
| 2019 |
Torelli NJ, Akhtar A, DeFrees K, Jaishankar P, Pemberton OA, Zhang X, Johnson C, Renslo AR, Chen Y. Active-site druggability of carbapenemases and broad-spectrum inhibitor discovery. Acs Infectious Diseases. PMID 30942078 DOI: 10.2210/Pdb6M7I/Pdb |
0.787 |
|
| 2019 |
DeFrees K, Kemp MT, ElHilali-Pollard X, Zhang X, Mohamed A, Chen Y, Renslo AR. An empirical study of amide–heteroarene π-stacking interactions using reversible inhibitors of a bacterial serine hydrolase Organic Chemistry Frontiers. 6: 1749-1756. DOI: 10.1039/C9QO00342H |
0.768 |
|
| 2018 |
Pope L, Arrigoni C, Lou H, Bryant C, Gallardo-Godoy A, Renslo AR, Minor DL. Protein and chemical determinants of BL-1249 action and selectivity for K2P channels. Acs Chemical Neuroscience. PMID 30089357 DOI: 10.1021/Acschemneuro.8B00337 |
0.329 |
|
| 2018 |
Pemberton OA, Zhang X, Nichols DA, DeFrees K, Jaishankar P, Bonnet R, Adams J, Shaw LN, Renslo AR, Chen Y. Antibacterial spectrum of a tetrazole-based reversible inhibitor of serine β-lactamases. Antimicrobial Agents and Chemotherapy. PMID 29844038 DOI: 10.1128/Aac.02563-17 |
0.774 |
|
| 2018 |
Spangler B, Kline T, Hanson J, Li X, Zhou S, Wells JA, Sato AK, Renslo AR. Toward a Ferrous Iron-Cleavable Linker for Antibody-Drug Conjugates. Molecular Pharmaceutics. PMID 29569925 DOI: 10.1021/Acs.Molpharmaceut.8B00242 |
0.802 |
|
| 2018 |
Wertz I, Kategaya L, Lello PD, Rouge L, Pastor R, Clark KR, Drummond J, Kleinheinz T, Lin E, Upton J, Prakash S, Heideker J, McCleland M, Ritorto MS, Alessi DR, ... ... Renslo AR, et al. Abstract SY23-03: Development and mechanistic characterization of USP7 deubiquitinase inhibitors Cancer Research. 78. DOI: 10.1158/1538-7445.Am2018-Sy23-03 |
0.333 |
|
| 2017 |
Camarena V, Sant DW, Huff TC, Mustafi S, Muir RK, Aron AT, Chang CJ, Renslo AR, Monje P, Wang G. cAMP signaling regulates DNA hydroxymethylation by augmenting the intracellular labile ferrous iron pool. Elife. 6. PMID 29239726 DOI: 10.7554/Elife.29750 |
0.779 |
|
| 2017 |
Aron AT, Heffern MC, Lonergan ZR, Vander Wal MN, Blank BR, Spangler B, Zhang Y, Park HM, Stahl A, Renslo AR, Skaar EP, Chang CJ. In vivo bioluminescence imaging of labile iron accumulation in a murine model of Acinetobacter baumannii infection. Proceedings of the National Academy of Sciences of the United States of America. PMID 29138321 DOI: 10.1073/Pnas.1708747114 |
0.8 |
|
| 2017 |
Kategaya L, Di Lello P, Rougé L, Pastor R, Clark KR, Drummond J, Kleinheinz T, Lin E, Upton JP, Prakash S, Heideker J, McCleland M, Ritorto MS, Alessi DR, Trost M, ... ... Renslo AR, et al. USP7 small-molecule inhibitors interfere with ubiquitin binding. Nature. PMID 29045385 DOI: 10.1038/Nature24006 |
0.326 |
|
| 2017 |
Acker TM, Gable JE, Bohn MF, Jaishankar P, Thompson MC, Fraser JS, Renslo AR, Craik CS. Allosteric Inhibitors, Crystallography and Comparative Analysis Reveal Network of Coordinated Movement Across Human Herpesvirus Proteases. Journal of the American Chemical Society. PMID 28759216 DOI: 10.1021/Jacs.7B04030 |
0.302 |
|
| 2017 |
Blank BR, Gut J, Rosenthal PJ, Renslo AR. Enantioselective Synthesis and in Vivo Evaluation of Regioisomeric Analogues of the Antimalarial Arterolane. Journal of Medicinal Chemistry. PMID 28692297 DOI: 10.1021/Acs.Jmedchem.7B00699 |
0.793 |
|
| 2017 |
Camarena V, Sant DW, Huff TC, Mustafi S, Muir RK, Aron AT, Chang CJ, Renslo AR, Monje PV, Wang G. Author response: cAMP signaling regulates DNA hydroxymethylation by augmenting the intracellular labile ferrous iron pool Elife. DOI: 10.7554/Elife.29750.032 |
0.776 |
|
| 2016 |
Spangler B, Fontaine SD, Shi Y, Sambucetti L, Mattis AN, Hann B, Wells JA, Renslo AR. A Novel Tumor-Activated Prodrug Strategy Targeting Ferrous Iron Is Effective in Multiple Preclinical Cancer Models. Journal of Medicinal Chemistry. PMID 27936709 DOI: 10.1021/Acs.Jmedchem.6B01470 |
0.803 |
|
| 2016 |
Hallenbeck KK, Turner DM, Renslo AR, Arkin MR. Covalent Strategies in Structure-Guided Drug Discovery. Current Topics in Medicinal Chemistry. PMID 27449257 DOI: 10.2174/1568026616666160719163839 |
0.53 |
|
| 2016 |
Spangler B, Morgan CW, Fontaine SD, Vander Wal MN, Chang CJ, Wells JA, Renslo AR. A reactivity-based probe of the intracellular labile ferrous iron pool. Nature Chemical Biology. PMID 27376690 DOI: 10.1038/Nchembio.2116 |
0.804 |
|
| 2016 |
Hearn BR, Jaishankar P, Sidrauski C, Tsai JC, Vedantham P, Fontaine SD, Walter P, Renslo AR. Structure-Activity Studies of Bis-O-Arylglycolamides: Inhibitors of the Integrated Stress Response. Chemmedchem. PMID 26789650 DOI: 10.1002/Cmdc.201500483 |
0.728 |
|
| 2015 |
Lauterwasser EM, Fontaine SD, Li H, Gut J, Katneni K, Charman SA, Rosenthal PJ, Bogyo M, Renslo AR. Trioxolane-Mediated Delivery of Mefloquine Limits Brain Exposure in a Mouse Model of Malaria. Acs Medicinal Chemistry Letters. 6: 1145-1149. PMID 26617969 DOI: 10.1021/Acsmedchemlett.5B00296 |
0.782 |
|
| 2015 |
Mott BT, Eastman RT, Guha R, Sherlach KS, Siriwardana A, Shinn P, McKnight C, Michael S, Lacerda-Queiroz N, Patel PR, Khine P, Sun H, Kasbekar M, Aghdam N, Fontaine SD, ... ... Renslo AR, et al. High-throughput matrix screening identifies synergistic and antagonistic antimalarial drug combinations. Scientific Reports. 5: 13891. PMID 26403635 DOI: 10.1038/Srep13891 |
0.763 |
|
| 2015 |
Neitz RJ, Bryant C, Chen S, Gut J, Hugo Caselli E, Ponce S, Chowdhury S, Xu H, Arkin MR, Ellman JA, Renslo AR. Tetrafluorophenoxymethyl ketone cruzain inhibitors with improved pharmacokinetic properties as therapeutic leads for Chagas' disease. Bioorganic & Medicinal Chemistry Letters. 25: 4834-7. PMID 26144347 DOI: 10.1016/J.Bmcl.2015.06.066 |
0.327 |
|
| 2015 |
Nichols DA, Hargis JC, Sanishvili R, Jaishankar P, Defrees K, Smith EW, Wang KK, Prati F, Renslo AR, Woodcock HL, Chen Y. Ligand-Induced Proton Transfer and Low-Barrier Hydrogen Bond Revealed by X-ray Crystallography. Journal of the American Chemical Society. 137: 8086-95. PMID 26057252 DOI: 10.1021/Jacs.5B00749 |
0.772 |
|
| 2015 |
Sidrauski C, Tsai JC, Kampmann M, Hearn BR, Vedantham P, Jaishankar P, Sokabe M, Mendez AS, Newton BW, Tang EL, Verschueren E, Johnson JR, Krogan NJ, Fraser CS, Weissman JS, ... Renslo AR, et al. Pharmacological dimerization and activation of the exchange factor eIF2B antagonizes the integrated stress response. Elife. 4: e07314. PMID 25875391 DOI: 10.7554/Elife.07314 |
0.308 |
|
| 2015 |
Chimenti MS, Bulfer SL, Neitz RJ, Renslo AR, Jacobson MP, James TL, Arkin MR, Kelly MJ. A Fragment-Based Ligand Screen Against Part of a Large Protein Machine: The ND1 Domains of the AAA+ ATPase p97/VCP. Journal of Biomolecular Screening. 20: 788-800. PMID 25690569 DOI: 10.1177/1087057115570550 |
0.316 |
|
| 2015 |
Zhou Y, Vedantham P, Lu K, Agudelo J, Carrion R, Nunneley JW, Barnard D, Pöhlmann S, McKerrow JH, Renslo AR, Simmons G. Protease inhibitors targeting coronavirus and filovirus entry. Antiviral Research. 116: 76-84. PMID 25666761 DOI: 10.1016/J.Antiviral.2015.01.011 |
0.312 |
|
| 2015 |
Fontaine SD, Spangler B, Gut J, Lauterwasser EM, Rosenthal PJ, Renslo AR. Drug delivery to the malaria parasite using an arterolane-like scaffold. Chemmedchem. 10: 47-51. PMID 25314098 DOI: 10.1002/Cmdc.201402362 |
0.78 |
|
| 2015 |
Neitz RJ, Chen S, Supek F, Yeh V, Kellar D, Gut J, Bryant C, Gallardo-Godoy A, Molteni V, Roach SL, Khare S, Stinson M, Chatterjee AK, Robertson S, Renslo AR, et al. Lead identification to clinical candidate selection: drugs for Chagas disease. Journal of Biomolecular Screening. 20: 101-11. PMID 25281737 DOI: 10.1177/1087057114553103 |
0.314 |
|
| 2014 |
Turner DM, Tom CT, Renslo AR. Simple plate-based, parallel synthesis of disulfide fragments using the CuAAC click reaction. Acs Combinatorial Science. 16: 661-4. PMID 25353066 DOI: 10.1021/Co500132Q |
0.452 |
|
| 2014 |
Fontaine SD, DiPasquale AG, Renslo AR. Efficient and stereocontrolled synthesis of 1,2,4-trioxolanes useful for ferrous iron-dependent drug delivery. Organic Letters. 16: 5776-9. PMID 25331549 DOI: 10.1021/Ol5028392 |
0.795 |
|
| 2014 |
Gable JE, Lee GM, Jaishankar P, Hearn BR, Waddling CA, Renslo AR, Craik CS. Broad-spectrum allosteric inhibition of herpesvirus proteases. Biochemistry. 53: 4648-60. PMID 24977643 DOI: 10.1021/Bi5003234 |
0.314 |
|
| 2014 |
Debnath A, Shahinas D, Bryant C, Hirata K, Miyamoto Y, Hwang G, Gut J, Renslo AR, Pillai DR, Eckmann L, Reed SL, McKerrow JH. Hsp90 inhibitors as new leads to target parasitic diarrheal diseases. Antimicrobial Agents and Chemotherapy. 58: 4138-44. PMID 24820073 DOI: 10.1128/Aac.02576-14 |
0.346 |
|
| 2014 |
Arkin MR, Ang KK, Chen S, Davies J, Merron C, Tang Y, Wilson CG, Renslo AR. UCSF Small Molecule Discovery Center: innovation, collaboration and chemical biology in the Bay Area. Combinatorial Chemistry & High Throughput Screening. 17: 333-42. PMID 24661212 DOI: 10.2174/1386207317666140323133841 |
0.321 |
|
| 2014 |
Nichols DA, Renslo AR, Chen Y. Fragment-based inhibitor discovery against β-lactamase. Future Medicinal Chemistry. 6: 413-27. PMID 24635522 DOI: 10.4155/Fmc.14.10 |
0.322 |
|
| 2014 |
Murray J, Giannetti AM, Steffek M, Gibbons P, Hearn BR, Cohen F, Tam C, Pozniak C, Bravo B, Lewcock J, Jaishankar P, Ly CQ, Zhao X, Tang Y, Chugha P, ... ... Renslo AR, et al. Tailoring small molecules for an allosteric site on procaspase-6. Chemmedchem. 9: 73-7, 2. PMID 24259468 DOI: 10.1002/Cmdc.201300424 |
0.332 |
|
| 2014 |
Peniche AG, Osorio Y, Renslo AR, Frantz DE, Melby PC, Travi BL. Development of an ex vivo lymph node explant model for identification of novel molecules active against Leishmania major. Antimicrobial Agents and Chemotherapy. 58: 78-87. PMID 24126577 DOI: 10.1128/Aac.00887-13 |
0.327 |
|
| 2013 |
Renslo AR. Antimalarial Drug Discovery: From Quinine to the Dream of Eradication. Acs Medicinal Chemistry Letters. 4: 1126-1128. PMID 24790706 DOI: 10.1021/Ml4004414 |
0.336 |
|
| 2013 |
Deu E, Chen IT, Lauterwasser EM, Valderramos J, Li H, Edgington LE, Renslo AR, Bogyo M. Ferrous iron-dependent drug delivery enables controlled and selective release of therapeutic agents in vivo. Proceedings of the National Academy of Sciences of the United States of America. 110: 18244-9. PMID 24145449 DOI: 10.1073/Pnas.1312782110 |
0.819 |
|
| 2013 |
Nishino M, Choy JW, Gushwa NN, Oses-Prieto JA, Koupparis K, Burlingame AL, Renslo AR, McKerrow JH, Taunton J. Hypothemicin, a fungal natural product, identifies therapeutic targets in Trypanosoma brucei Elife. 2013. PMID 23853713 DOI: 10.7554/Elife.00712 |
0.75 |
|
| 2013 |
Choy JW, Bryant C, Calvet CM, Doyle PS, Gunatilleke SS, Leung SS, Ang KK, Chen S, Gut J, Oses-Prieto JA, Johnston JB, Arkin MR, Burlingame AL, Taunton J, Jacobson MP, ... ... Renslo AR, et al. Chemical-biological characterization of a cruzain inhibitor reveals a second target and a mammalian off-target. Beilstein Journal of Organic Chemistry. 9: 15-25. PMID 23400640 DOI: 10.3762/Bjoc.9.3 |
0.77 |
|
| 2013 |
Nishino M, Choy JW, Gushwa NN, Oses-Prieto JA, Koupparis K, Burlingame AL, Renslo AR, McKerrow JH, Taunton J. Correction: Hypothemycin, a fungal natural product, identifies therapeutic targets in Trypanosoma brucei Elife. 2. DOI: 10.7554/Elife.01214 |
0.742 |
|
| 2013 |
Nishino M, Choy JW, Gushwa NN, Oses-Prieto JA, Koupparis K, Burlingame AL, Renslo AR, McKerrow JH, Taunton J. Author response: Hypothemycin, a fungal natural product, identifies therapeutic targets in Trypanosoma brucei Elife. DOI: 10.7554/Elife.00712.010 |
0.74 |
|
| 2012 |
Mahajan SS, Gut J, Rosenthal PJ, Renslo AR. Ferrous iron-dependent delivery of therapeutic agents to the malaria parasite. Future Medicinal Chemistry. 4: 2241-9. PMID 23234548 DOI: 10.4155/Fmc.12.174 |
0.776 |
|
| 2012 |
Nichols DA, Jaishankar P, Larson W, Smith E, Liu G, Beyrouthy R, Bonnet R, Renslo AR, Chen Y. Structure-based design of potent and ligand-efficient inhibitors of CTX-M class A β-lactamase. Journal of Medicinal Chemistry. 55: 2163-72. PMID 22296601 DOI: 10.1021/Jm2014138 |
0.303 |
|
| 2011 |
Hartwig CL, Lauterwasser EM, Mahajan SS, Hoke JM, Cooper RA, Renslo AR. Investigating the antimalarial action of 1,2,4-trioxolanes with fluorescent chemical probes. Journal of Medicinal Chemistry. 54: 8207-13. PMID 22023506 DOI: 10.1021/Jm2012003 |
0.778 |
|
| 2011 |
Robertson SA, Renslo AR. Drug discovery for neglected tropical diseases at the Sandler Center. Future Medicinal Chemistry. 3: 1279-88. PMID 21859302 DOI: 10.4155/Fmc.11.85 |
0.357 |
|
| 2011 |
Ang KK, Ratnam J, Gut J, Legac J, Hansell E, Mackey ZB, Skrzypczynska KM, Debnath A, Engel JC, Rosenthal PJ, McKerrow JH, Arkin MR, Renslo AR. Mining a cathepsin inhibitor library for new antiparasitic drug leads. Plos Neglected Tropical Diseases. 5: e1023. PMID 21572521 DOI: 10.1371/Journal.Pntd.0001023 |
0.339 |
|
| 2011 |
Mahajan SS, Deu E, Lauterwasser EM, Leyva MJ, Ellman JA, Bogyo M, Renslo AR. A fragmenting hybrid approach for targeted delivery of multiple therapeutic agents to the malaria parasite. Chemmedchem. 6: 415-9. PMID 21360816 DOI: 10.1002/Cmdc.201100002 |
0.806 |
|
| 2011 |
Osorio Y, Travi BL, Renslo AR, Peniche AG, Melby PC. Identification of small molecule lead compounds for visceral leishmaniasis using a novel ex vivo splenic explant model system. Plos Neglected Tropical Diseases. 5: e962. PMID 21358812 DOI: 10.1371/Journal.Pntd.0000962 |
0.36 |
|
| 2011 |
Gallardo-Godoy A, Gever J, Fife KL, Silber BM, Prusiner SB, Renslo AR. 2-Aminothiazoles as therapeutic leads for prion diseases. Journal of Medicinal Chemistry. 54: 1010-21. PMID 21247166 DOI: 10.1021/Jm101250Y |
0.327 |
|
| 2011 |
Mahajan SS, Deu E, Lauterwasser EMW, Leyva MJ, Ellman JA, Bogyo M, Renslo AR. Inside Cover: A Fragmenting Hybrid Approach for Targeted Delivery of Multiple Therapeutic Agents to the Malaria Parasite (ChemMedChem 3/2011) Chemmedchem. 6: 382-382. DOI: 10.1002/Cmdc.201190006 |
0.713 |
|
| 2010 |
Renslo AR. Antibacterial oxazolidinones: Emerging structure-toxicity relationships Expert Review of Anti-Infective Therapy. 8: 565-574. PMID 20455685 DOI: 10.1586/Eri.10.26 |
0.303 |
|
| 2010 |
Ghaemmaghami S, May BC, Renslo AR, Prusiner SB. Discovery of 2-aminothiazoles as potent antiprion compounds. Journal of Virology. 84: 3408-12. PMID 20032192 DOI: 10.1128/Jvi.02145-09 |
0.329 |
|
| 2009 |
Abdulla MH, Ruelas DS, Wolff B, Snedecor J, Lim KC, Xu F, Renslo AR, Williams J, McKerrow JH, Caffrey CR. Drug discovery for schistosomiasis: hit and lead compounds identified in a library of known drugs by medium-throughput phenotypic screening. Plos Neglected Tropical Diseases. 3: e478. PMID 19597541 DOI: 10.1371/Journal.Pntd.0000478 |
0.335 |
|
| 2006 |
Renslo AR, McKerrow JH. Drug discovery and development for neglected parasitic diseases Nature Chemical Biology. 2: 701-710. PMID 17108988 DOI: 10.1038/Nchembio837 |
0.328 |
|
| 2006 |
Renslo AR, Luehr GW, Gordeev MF. Recent developments in the identification of novel oxazolidinone antibacterial agents Bioorganic and Medicinal Chemistry. 14: 4227-4240. PMID 16527486 DOI: 10.1016/J.Bmc.2006.01.068 |
0.301 |
|
| 2005 |
Renslo AR, Jaishankar P, Venkatachalam R, Hackbarth C, Lopez S, Patel DV, Gordeev MF. Conformational constraint in oxazolidinone antibacterials. Synthesis and structure-activity studies of (azabicyclo[3.1.0]hexylphenyl)oxazolidinones Journal of Medicinal Chemistry. 48: 5009-5024. PMID 16033280 DOI: 10.1021/Jm058204J |
0.315 |
|
| 2003 |
Amos DT, Renslo AR, Danheiser RL. Intramolecular [4 + 2] cycloadditions of iminoacetonitriles: a new class of azadienophiles for hetero Diels-Alder reactions. Journal of the American Chemical Society. 125: 4970-1. PMID 12708834 DOI: 10.1021/ja034629o |
0.465 |
|
| 2003 |
Danheiser RL, Renslo AR, Amos DT, Wright GT. Preparation of Substituted Pyridines Via Regiocontrolled [4 + 2] Cycloadditions of Oximinosulfonates: Methyl 5‐Methylpyridine‐2‐Carboxylate Organic Syntheses. 80: 133-143. DOI: 10.1002/0471264180.Os080.16 |
0.512 |
|
| 2003 |
Danheiser RL, Renslo AR, Amos DT, Wright GT. Preparation of substituted pyridines via regiocontrolled [4 + 2] cycloadditions of oximinosulfonates: Methyl 5-methylpyridine-2-carboxylate. (2-Pyridinecarboxylic acid, 5-methyl-, methyl ester) Organic Syntheses. 80: 133-143. |
0.443 |
|
| 2000 |
Tucci FC, Renslo AR, Rudkevich DM, Rebek Jr. Nanoscale Container Structures and Their Host - Guest Properties We are grateful for financial support from the Skaggs Research Foundation and the National Institutes of Health. Dr. Laura Pasternack and Dr. Takeharu Haino are sincerely acknowledged for assistance with the 2D NMR experiments and experimental advise, respectively. Angewandte Chemie (International Ed. in English). 39: 1076-1079. PMID 10760927 DOI: 10.1002/(Sici)1521-3773(20000317)39:6<1076::Aid-Anie1076>3.0.Co;2-E |
0.568 |
|
| 2000 |
Renslo AR, Tucci FC, Rudkevich DM, Rebek J. Synthesis and assembly of self-complementary cavitands Journal of the American Chemical Society. 122: 4573-4582. DOI: 10.1021/Ja993922E |
0.573 |
|
| 2000 |
Tucci FC, Renslo AR, Rudkevich DM, Rebek J. Nanoscale-container structures and their host - Guest properties Angewandte Chemie - International Edition. 39: 1076-1079. DOI: 10.1002/(SICI)1521-3773(20000317)39:6<1076::AID-ANIE1076>3.0.CO;2-E |
0.539 |
|
| 1999 |
Weinstein RD, Renslo AR, Danheiser RL, Tester JW. Silica-Promoted Diels-Alder Reactions in Carbon Dioxide from Gaseous to Supercritical Conditions Journal of Physical Chemistry B. 103: 2878-2887. DOI: 10.1021/Jp984227G |
0.504 |
|
| 1999 |
Lützen A, Renslo AR, Schalley CA, O'Leary BM, Rebek J. Encapsulation of ion-molecule complexes: Second-sphere supramolecular chemistry [26] Journal of the American Chemical Society. 121: 7455-7456. DOI: 10.1021/Ja991747W |
0.613 |
|
| 1998 |
Renslo AR, Danheiser RL. Synthesis of substituted pyridines via regiocontrolled [4 + 2] cycloadditions of oximinosulfonates Journal of Organic Chemistry. 63: 7840-7850. DOI: 10.1021/Jo981014E |
0.532 |
|
| 1997 |
Renslo AR, Weinstein RD, Tester JW, Danheiser RL. Concerning the Regiochemical Course of the Diels-Alder Reaction in Supercritical Carbon Dioxide. The Journal of Organic Chemistry. 62: 4530-4533. PMID 11671790 DOI: 10.1021/Jo9704523 |
0.496 |
|
| 1996 |
Weinstein RD, Renslo AR, Danheiser RL, Harris JG, Tester JW. Inetic correlation of Diels-Alder reactions in supercritical carbon dioxide The Journal of Physical Chemistry. 100: 12337-12341. DOI: 10.1021/Jp960180S |
0.509 |
|
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