| Year |
Citation |
Score |
| 2019 |
Bilobrov V, Sokolova V, Prylutska S, Panchuk R, Litsis O, Osetskyi V, Evstigneev M, Prylutskyy Y, Epple M, Ritter U, Rohr J. A Novel Nanoconjugate of Landomycin A with C60 Fullerene for Cancer Targeted Therapy: In Vitro Studies. Cellular and Molecular Bioengineering. 12: 41-51. PMID 31719898 DOI: 10.1007/S12195-018-0548-5 |
0.301 |
|
| 2019 |
Wheeler R, Yu X, Hou C, Mitra P, Chen JM, Herkules F, Ivanov DN, Tsodikov OV, Rohr J. Discovery of a Cryptic Intermediate in Late Steps of Mithramycin Biosynthesis. Angewandte Chemie (International Ed. in English). PMID 31702856 DOI: 10.1002/Anie.201910241 |
0.36 |
|
| 2019 |
Savi DC, Noriler SA, Ponomareva LV, Thorson JS, Rohr J, Glienke C, Shaaban KA. Dihydroisocoumarins produced by Diaporthe cf. heveae LGMF1631 inhibiting citrus pathogens. Folia Microbiologica. PMID 31401763 DOI: 10.1007/S12223-019-00746-8 |
0.319 |
|
| 2019 |
Noriler SA, Savi DC, Ponomareva LV, Rohr J, Thorson JS, Rodrigues R, Glienke C, Shaaban KA. Vochysiamides A and B: Two new bioactive carboxamides produced by the new species Diaporthe vochysiae. Fitoterapia. 104273. PMID 31344395 DOI: 10.1016/J.Fitote.2019.104273 |
0.344 |
|
| 2019 |
Hou C, Rohr J, Parkin S, Tsodikov OV. How mithramycin stereochemistry dictates its structure and DNA binding function. Medchemcomm. 10: 735-741. PMID 31191864 DOI: 10.1039/C9Md00100J |
0.3 |
|
| 2019 |
Hayden RC, Hou C, Mitra P, Mandal A, Rohr J, Thorson J, Tsodikov O, Leggas M. Abstract 2954: Mithramycin analogues disrupt ETS transcription factor DNA binding Cancer Research. 79: 2954-2954. DOI: 10.1158/1538-7445.Sabcs18-2954 |
0.301 |
|
| 2018 |
Savi DC, Shaaban KA, Gos FMW, Thorson JS, Glienke C, Rohr J. Secondary metabolites produced by Microbacterium sp. LGMB471 with antifungal activity against the phytopathogen Phyllosticta citricarpa. Folia Microbiologica. PMID 30565048 DOI: 10.1007/S12223-018-00668-X |
0.324 |
|
| 2018 |
Cui Z, Wang XC, Liu X, Lemke A, Koppermann S, Ducho C, Rohr J, Thorson JS, Van Lanen SG. Self-Resistance During Muraymycin Biosynthesis: A Complementary Nucleotidyltransferase and Phosphotransferase with Identical Modification Sites and Distinct Temporal Order. Antimicrobial Agents and Chemotherapy. PMID 29735559 DOI: 10.1128/Aac.00193-18 |
0.398 |
|
| 2018 |
de Medeiros AG, Savi DC, Mitra P, Shaaban KA, Jha AK, Thorson JS, Rohr J, Glienke C. Bioprospecting of Diaporthe terebinthifolii LGMF907 for antimicrobial compounds. Folia Microbiologica. PMID 29497981 DOI: 10.1007/S12223-018-0587-2 |
0.345 |
|
| 2018 |
Savi DC, Shaaban KA, Gos FMWR, Ponomareva LV, Thorson JS, Glienke C, Rohr J. Phaeophleospora vochysiae Savi & Glienke sp. nov. Isolated from Vochysia divergens Found in the Pantanal, Brazil, Produces Bioactive Secondary Metabolites. Scientific Reports. 8: 3122. PMID 29449610 DOI: 10.1038/S41598-018-21400-2 |
0.336 |
|
| 2017 |
Krafczyk R, Macošek J, Jagtap PKA, Gast D, Wunder S, Mitra P, Jha AK, Rohr J, Hoffmann-Röder A, Jung K, Hennig J, Lassak J. Structural Basis for EarP-Mediated Arginine Glycosylation of Translation Elongation Factor EF-P. Mbio. 8. PMID 28951478 DOI: 10.1128/Mbio.01412-17 |
0.31 |
|
| 2017 |
Gos FMWR, Savi DC, Shaaban KA, Thorson JS, Aluizio R, Possiede YM, Rohr J, Glienke C. Antibacterial Activity of Endophytic Actinomycetes Isolated from the Medicinal Plant Vochysia divergens (Pantanal, Brazil). Frontiers in Microbiology. 8: 1642. PMID 28932210 DOI: 10.3389/Fmicb.2017.01642 |
0.308 |
|
| 2017 |
Salem SM, Weidenbach S, Rohr J. Two Cooperative Glycosyltransferases are Responsible for the Sugar Diversity of Saquayamycins Isolated from Streptomyces sp. KY 40-1. Acs Chemical Biology. PMID 28892347 DOI: 10.1021/Acschembio.7B00453 |
0.407 |
|
| 2017 |
Gao G, Liu X, Xu M, Wang Y, Zhang F, Xu L, Lv J, Long Q, Kang Q, Ou HY, Wang Y, Rohr J, Deng Z, Jiang M, Lin S, et al. Formation of an Angular Aromatic Polyketide from a Linear Anthrene Precursor via Oxidative Rearrangement. Cell Chemical Biology. PMID 28712746 DOI: 10.1016/J.Chembiol.2017.06.008 |
0.374 |
|
| 2017 |
Wang X, Elshahawi SI, Cai W, Zhang Y, Ponomareva LV, Chen X, Copley GC, Hower JC, Zhan CG, Parkin S, Rohr J, Van Lanen SG, Shaaban KA, Thorson JS. Bi- and Tetracyclic Spirotetronates from the Coal Mine Fire Isolate Streptomyces sp. LC-6-2. Journal of Natural Products. PMID 28358212 DOI: 10.1021/Acs.Jnatprod.7B00108 |
0.306 |
|
| 2017 |
Panchuk RR, Lehka LV, Terenzi A, Matselyukh BP, Rohr J, Jha AK, Downey T, Kril' IJ, Herbacek I, van Schonhoven S, Heffeter P, Stoika RS, Berger W. Rapid generation of hydrogen peroxide contributes to the complex cell death induction by the angucycline antibiotic landomycin E. Free Radical Biology & Medicine. PMID 28189848 DOI: 10.1016/J.Freeradbiomed.2017.02.024 |
0.604 |
|
| 2017 |
Wang G, Chen J, Zhu H, Rohr J. One-Pot Enzymatic Total Synthesis of Presteffimycinone, an Early Intermediate of the Anthracycline Antibiotic Steffimycin Biosynthesis. Organic Letters. PMID 28102686 DOI: 10.1021/Acs.Orglett.6B03708 |
0.33 |
|
| 2017 |
Goswami A, Liu X, Cai W, Wyche TP, Bugni TS, Meurillon M, Peyrottes S, Perigaud C, Nonaka K, Rohr J, Van Lanen SG. Evidence that Oxidative Dephosphorylation by the Non-heme Fe(II), α-Ketoglutarate:UMP Oxygenase Occurs by Stereospecific Hydroxylation. Febs Letters. PMID 28074470 DOI: 10.1002/1873-3468.12554 |
0.308 |
|
| 2016 |
Blundell RD, Williams SJ, Arras SD, Chitty JL, Blake KL, Ericsson DJ, Tibrewal N, Rohr J, Koh YQ, Kappler U, Robertson AA, Butler MS, Cooper MA, Kobe B, Fraser JA. Disruption of de Novo Adenosine Triphosphate (ATP) Biosynthesis Abolishes Virulence in Cryptococcus neoformans. Acs Infectious Diseases. 2: 651-663. PMID 27759389 DOI: 10.1021/Acsinfecdis.6B00121 |
0.36 |
|
| 2016 |
Pahari P, Saikia UP, Das TP, Damodaran C, Rohr J. Synthesis of Psoralidin derivatives and their anticancer activity: First synthesis of Lespeflorin I(1). Tetrahedron. 72: 3324-3334. PMID 27698514 DOI: 10.1016/J.Tet.2016.04.066 |
0.334 |
|
| 2016 |
Jackson D, Yu X, Wang G, Patel A, Barajas J, Sasaki E, Metsa-Ketala M, Liu HW, Rohr J, Tsai SS. Insights Into Complex Oxidation During BE-7585A Biosynthesis: Structural Determination and Analysis of the Polyketide Monooxygenase BexE. Acs Chemical Biology. PMID 26813028 DOI: 10.1021/Acschembio.5B00913 |
0.34 |
|
| 2015 |
Chen JM, Hou C, Wang G, Tsodikov OV, Rohr J. Structural insight into MtmC, a bifunctional ketoreductase-methyltransferase involved in the assembly of the mithramycin trisaccharide chain. Biochemistry. 54: 2481-9. PMID 25587924 DOI: 10.1021/Bi501462G |
0.358 |
|
| 2015 |
Tam HK, Härle J, Gerhardt S, Rohr J, Wang G, Thorson JS, Bigot A, Lutterbeck M, Seiche W, Breit B, Bechthold A, Einsle O. Structural characterization of O- and C-glycosylating variants of the landomycin glycosyltransferase LanGT2. Angewandte Chemie (International Ed. in English). 54: 2811-5. PMID 25581707 DOI: 10.1002/Anie.201409792 |
0.344 |
|
| 2015 |
Savi DC, Shaaban KA, Vargas N, Ponomareva LV, Possiede YM, Thorson JS, Glienke C, Rohr J. Microbispora sp. LGMB259 endophytic actinomycete isolated from Vochysia divergens (Pantanal, Brazil) producing β-carbolines and indoles with biological activity. Current Microbiology. 70: 345-54. PMID 25385358 DOI: 10.1007/S00284-014-0724-3 |
0.336 |
|
| 2014 |
Braña AF, Rodríguez M, Pahari P, Rohr J, García LA, Blanco G. Activation and silencing of secondary metabolites in Streptomyces albus and Streptomyces lividans after transformation with cosmids containing the thienamycin gene cluster from Streptomyces cattleya. Archives of Microbiology. 196: 345-55. PMID 24633227 DOI: 10.1007/S00203-014-0977-Z |
0.372 |
|
| 2014 |
Singh S, Zhang J, Huber TD, Sunkara M, Hurley K, Goff RD, Wang G, Zhang W, Liu C, Rohr J, Van Lanen SG, Morris AJ, Thorson JS. Facile chemoenzymatic strategies for the synthesis and utilization of S-adenosyl-(L)-methionine analogues. Angewandte Chemie (International Ed. in English). 53: 3965-9. PMID 24616228 DOI: 10.1002/Anie.201308272 |
0.362 |
|
| 2013 |
Bosserman MA, Downey T, Noinaj N, Buchanan SK, Rohr J. Molecular insight into substrate recognition and catalysis of Baeyer-Villiger monooxygenase MtmOIV, the key frame-modifying enzyme in the biosynthesis of anticancer agent mithramycin. Acs Chemical Biology. 8: 2466-77. PMID 23992662 DOI: 10.1021/Cb400399B |
0.665 |
|
| 2013 |
Garcia I, Vior NM, González-SabÃn J, Braña AF, Rohr J, Moris F, Méndez C, Salas JA. Engineering the biosynthesis of the polyketide-nonribosomal peptide collismycin A for generation of analogs with neuroprotective activity. Chemistry & Biology. 20: 1022-32. PMID 23911584 DOI: 10.1016/J.Chembiol.2013.06.014 |
0.348 |
|
| 2013 |
Scott D, Chen JM, Bae Y, Rohr J. Semi-synthetic mithramycin SA derivatives with improved anticancer activity. Chemical Biology & Drug Design. 81: 615-24. PMID 23331575 DOI: 10.1111/Cbdd.12107 |
0.312 |
|
| 2013 |
Chen J, Wang G, Rohr J. The Biosynthetic Pathway to TDP-D-Fucofuranose, the Sugar Donor Substrate for the C-Glycosyltranferase Involved in Gilvocarcin V Biosynthesis Planta Medica. 79. DOI: 10.1055/S-0033-1348674 |
0.343 |
|
| 2013 |
Downey T, Bosserman M, Noinaj N, Buchanan S, Rohr J. Investigating and Re-Engineering Baeyer-Villiger Monooxygenase MtmOIV for Combinatorial Biosynthesis of Novel Aureolic Acid Anticancer Drug Analogues Planta Medica. 79. DOI: 10.1055/S-0033-1348553 |
0.6 |
|
| 2012 |
Barnard-Britson S, Chi X, Nonaka K, Spork AP, Tibrewal N, Goswami A, Pahari P, Ducho C, Rohr J, Van Lanen SG. Amalgamation of nucleosides and amino acids in antibiotic biosynthesis: discovery of an L-threonine:uridine-5'-aldehyde transaldolase. Journal of the American Chemical Society. 134: 18514-7. PMID 23110675 DOI: 10.1021/Ja308185Q |
0.387 |
|
| 2012 |
Tibrewal N, Pahari P, Wang G, Kharel MK, Morris C, Downey T, Hou Y, Bugni TS, Rohr J. Baeyer-Villiger C-C bond cleavage reaction in gilvocarcin and jadomycin biosynthesis. Journal of the American Chemical Society. 134: 18181-4. PMID 23102024 DOI: 10.1021/Ja3081154 |
0.653 |
|
| 2012 |
Shaaban KA, Shepherd MD, Ahmed TA, Nybo SE, Leggas M, Rohr J. Pyramidamycins A-D and 3-hydroxyquinoline-2-carboxamide; cytotoxic benzamides from Streptomyces sp. DGC1. The Journal of Antibiotics. 65: 615-22. PMID 23047245 DOI: 10.1038/Ja.2012.81 |
0.734 |
|
| 2012 |
Wang G, Pahari P, Kharel MK, Chen J, Zhu H, Van Lanen SG, Rohr J. Cooperation of two bifunctional enzymes in the biosynthesis and attachment of deoxysugars of the antitumor antibiotic mithramycin. Angewandte Chemie (International Ed. in English). 51: 10638-42. PMID 22997042 DOI: 10.1002/Anie.201205414 |
0.36 |
|
| 2012 |
Tibrewal N, Downey TE, Van Lanen SG, Ul Sharif E, O'Doherty GA, Rohr J. Roles of the synergistic reductive O-methyltransferase GilM and of O-methyltransferase GilMT in the gilvocarcin biosynthetic pathway. Journal of the American Chemical Society. 134: 12402-5. PMID 22800463 DOI: 10.1021/Ja305113D |
0.633 |
|
| 2012 |
Shaaban KA, Ahmed TA, Leggas M, Rohr J. Saquayamycins G-K, cytotoxic angucyclines from Streptomyces sp. Including two analogues bearing the aminosugar rednose. Journal of Natural Products. 75: 1383-92. PMID 22758660 DOI: 10.1021/Np300316B |
0.34 |
|
| 2012 |
Patrikainen P, Kallio P, Fan K, Klika KD, Shaaban KA, Mäntsälä P, Rohr J, Yang K, Niemi J, Metsä-Ketelä M. Tailoring enzymes involved in the biosynthesis of angucyclines contain latent context-dependent catalytic activities. Chemistry & Biology. 19: 647-55. PMID 22633416 DOI: 10.1016/J.Chembiol.2012.04.010 |
0.358 |
|
| 2012 |
Núñez LE, Nybo SE, González-Sabín J, Pérez M, Menéndez N, Braña AF, Shaaban KA, He M, Morís F, Salas JA, Rohr J, Méndez C. A novel mithramycin analogue with high antitumor activity and less toxicity generated by combinatorial biosynthesis. Journal of Medicinal Chemistry. 55: 5813-25. PMID 22578073 DOI: 10.1021/Jm300234T |
0.74 |
|
| 2012 |
Kharel MK, Rohr J. Delineation of gilvocarcin, jadomycin, and landomycin pathways through combinatorial biosynthetic enzymology. Current Opinion in Chemical Biology. 16: 150-61. PMID 22465094 DOI: 10.1016/J.Cbpa.2012.03.007 |
0.379 |
|
| 2012 |
Kharel MK, Pahari P, Shaaban KA, Wang G, Morris C, Rohr J. Elucidation of post-PKS tailoring steps involved in landomycin biosynthesis. Organic & Biomolecular Chemistry. 10: 4256-65. PMID 22454092 DOI: 10.1039/C2Ob07171A |
0.383 |
|
| 2012 |
Garcia I, Vior NM, Braña AF, González-Sabin J, Rohr J, Moris F, Méndez C, Salas JA. Elucidating the biosynthetic pathway for the polyketide-nonribosomal peptide collismycin A: mechanism for formation of the 2,2'-bipyridyl ring. Chemistry & Biology. 19: 399-413. PMID 22444595 DOI: 10.1016/J.Chembiol.2012.01.014 |
0.338 |
|
| 2012 |
Nybo SE, Shabaan KA, Kharel MK, Sutardjo H, Salas JA, Méndez C, Rohr J. Ketoolivosyl-tetracenomycin C: a new ketosugar bearing tetracenomycin reveals new insight into the substrate flexibility of glycosyltransferase ElmGT. Bioorganic & Medicinal Chemistry Letters. 22: 2247-50. PMID 22361136 DOI: 10.1016/J.Bmcl.2012.01.094 |
0.758 |
|
| 2012 |
Pahari P, Kharel MK, Shepherd MD, van Lanen SG, Rohr J. Enzymatic total synthesis of defucogilvocarcin M and its implications for gilvocarcin biosynthesis. Angewandte Chemie (International Ed. in English). 51: 1216-20. PMID 22223167 DOI: 10.1002/Anie.201105882 |
0.415 |
|
| 2012 |
Kharel MK, Pahari P, Shepherd MD, Tibrewal N, Nybo SE, Shaaban KA, Rohr J. Angucyclines: Biosynthesis, mode-of-action, new natural products, and synthesis. Natural Product Reports. 29: 264-325. PMID 22186970 DOI: 10.1039/C1Np00068C |
0.739 |
|
| 2012 |
Tibrewal N, Downey T, Rohr J. Synergistic reductive methyltransferase GILM and its crucial role in gilvocarcin biosynthetic pathway Planta Medica. 78. DOI: 10.1055/S-0032-1320333 |
0.605 |
|
| 2012 |
Wang G, Pahari P, Kharel M, Van Lanen S, Rohr J. Two bifunctional enzymes, MTM GIV and MTM C, involved in the biosynthesis of deoxysugar moieties of the antitumor antibiotic mithramycin Planta Medica. 78. DOI: 10.1055/S-0032-1320284 |
0.354 |
|
| 2011 |
Wang G, Kharel MK, Pahari P, Rohr J. Investigating Mithramycin deoxysugar biosynthesis: enzymatic total synthesis of TDP-D-olivose. Chembiochem : a European Journal of Chemical Biology. 12: 2568-71. PMID 21960454 DOI: 10.1002/Cbic.201100540 |
0.34 |
|
| 2011 |
Sleiman SF, Langley BC, Basso M, Berlin J, Xia L, Payappilly JB, Kharel MK, Guo H, Marsh JL, Thompson LM, Mahishi L, Ahuja P, MacLellan WR, Geschwind DH, Coppola G, ... Rohr J, et al. Mithramycin is a gene-selective Sp1 inhibitor that identifies a biological intersection between cancer and neurodegeneration. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 6858-70. PMID 21543616 DOI: 10.1523/Jneurosci.0710-11.2011 |
0.311 |
|
| 2011 |
Kharel MK, Lian H, Rohr J. Characterization of the TDP-D-ravidosamine biosynthetic pathway: one-pot enzymatic synthesis of TDP-D-ravidosamine from thymidine-5-phosphate and glucose-1-phosphate. Organic & Biomolecular Chemistry. 9: 1799-808. PMID 21264378 DOI: 10.1039/C0Ob00854K |
0.345 |
|
| 2011 |
Bosserman MA, Flórez AB, Shaaban KA, Braña AF, Salas JA, Méndez C, Rohr J. Characterization of the terminal activation step catalyzed by oxygenase CmmOIV of the chromomycin biosynthetic pathway from Streptomyces griseus. Biochemistry. 50: 1421-8. PMID 21244022 DOI: 10.1021/Bi1016205 |
0.364 |
|
| 2011 |
Yang Z, Chi X, Funabashi M, Baba S, Nonaka K, Pahari P, Unrine J, Jacobsen JM, Elliott GI, Rohr J, Van Lanen SG. Characterization of LipL as a non-heme, Fe(II)-dependent α-ketoglutarate:UMP dioxygenase that generates uridine-5'-aldehyde during A-90289 biosynthesis. The Journal of Biological Chemistry. 286: 7885-92. PMID 21216959 DOI: 10.1074/Jbc.M110.203562 |
0.302 |
|
| 2011 |
Shaaban KA, Srinivasan S, Kumar R, Damodaran C, Rohr J. Landomycins P-W, cytotoxic angucyclines from Streptomyces cyanogenus S-136. Journal of Natural Products. 74: 2-11. PMID 21188999 DOI: 10.1021/Np100469Y |
0.341 |
|
| 2011 |
Shepherd MD, Liu T, Méndez C, Salas JA, Rohr J. Engineered biosynthesis of gilvocarcin analogues with altered deoxyhexopyranose moieties. Applied and Environmental Microbiology. 77: 435-41. PMID 21075894 DOI: 10.1128/Aem.01774-10 |
0.353 |
|
| 2011 |
Shaaban KA, Stamatkin C, Damodaran C, Rohr J. 11-Deoxylandomycinone and landomycins X-Z, new cytotoxic angucyclin(on)es from a Streptomyces cyanogenus K62 mutant strain. The Journal of Antibiotics. 64: 141-50. PMID 20978514 DOI: 10.1038/Ja.2010.121 |
0.317 |
|
| 2010 |
Kharel MK, Shepherd MD, Nybo SE, Smith ML, Bosserman MA, Rohr J. Isolation of Streptomyces species from soil. Current Protocols in Microbiology. Unit 10E.4. PMID 21053254 DOI: 10.1002/9780471729259.Mc10E04S19 |
0.709 |
|
| 2010 |
Nybo SE, Shepherd MD, Bosserman MA, Rohr J. Genetic manipulation of Streptomyces species. Current Protocols in Microbiology. Unit 10E.3. PMID 21053253 DOI: 10.1002/9780471729259.Mc10E03S19 |
0.716 |
|
| 2010 |
Shepherd MD, Kharel MK, Zhu LL, van Lanen SG, Rohr J. Delineating the earliest steps of gilvocarcin biosynthesis: role of GilP and GilQ in starter unit specificity. Organic & Biomolecular Chemistry. 8: 3851-6. PMID 20617244 DOI: 10.1039/C0Ob00036A |
0.309 |
|
| 2010 |
Ostash B, Ostash I, Zhu L, Kharel MK, Luzhetskiǐ A, Bechthold A, Walker S, Rohr J, Fedorenko V. Properties of lanK-based regulatory circuit involved in landomycin biosynthesis in Streptomyces cyanogenus S136 Genetika. 46: 604-609. PMID 20583594 DOI: 10.1134/S1022795410050030 |
0.322 |
|
| 2010 |
Kharel MK, Pahari P, Lian H, Rohr J. Enzymatic total synthesis of rabelomycin, an angucycline group antibiotic. Organic Letters. 12: 2814-7. PMID 20486694 DOI: 10.1021/Ol1009009 |
0.356 |
|
| 2010 |
Kharel MK, Nybo SE, Shepherd MD, Rohr J. Cloning and characterization of the ravidomycin and chrysomycin biosynthetic gene clusters. Chembiochem : a European Journal of Chemical Biology. 11: 523-32. PMID 20140934 DOI: 10.1002/Cbic.200900673 |
0.748 |
|
| 2010 |
Kharel MK, Pahari P, Lian H, Rohr J. Corrigendum: GilR, an Unusual Lactone-Forming Enzyme Involved in Gilvocarcin Biosynthesis Chembiochem. 11: 1161-1161. DOI: 10.1002/Cbic.201090040 |
0.324 |
|
| 2009 |
Kharel MK, Pahari P, Lian H, Rohr J. GilR, an unusual lactone-forming enzyme involved in gilvocarcin biosynthesis. Chembiochem : a European Journal of Chemical Biology. 10: 1305-8. PMID 19388008 DOI: 10.1002/Cbic.200900130 |
0.331 |
|
| 2009 |
Beam MP, Bosserman MA, Noinaj N, Wehenkel M, Rohr J. Crystal structure of Baeyer-Villiger monooxygenase MtmOIV, the key enzyme of the mithramycin biosynthetic pathway . Biochemistry. 48: 4476-87. PMID 19364090 DOI: 10.1021/Bi8023509 |
0.743 |
|
| 2009 |
Pahari P, Rohr J. Total synthesis of psoralidin, an anticancer natural product. The Journal of Organic Chemistry. 74: 2750-4. PMID 19254011 DOI: 10.1021/Jo8025884 |
0.32 |
|
| 2009 |
Liu T, Kharel MK, Zhu L, Bright SA, Mattingly C, Adams VR, Rohr J. Inactivation of the ketoreductase gilU gene of the gilvocarcin biosynthetic gene cluster yields new analogues with partly improved biological activity. Chembiochem : a European Journal of Chemical Biology. 10: 278-86. PMID 19067453 DOI: 10.1002/Cbic.200800348 |
0.433 |
|
| 2009 |
Lombó F, Abdelfattah MS, Braña AF, Salas JA, Rohr J, Méndez C. Elucidation of oxygenation steps during oviedomycin biosynthesis and generation of derivatives with increased antitumor activity. Chembiochem : a European Journal of Chemical Biology. 10: 296-303. PMID 18988223 DOI: 10.1002/Cbic.200800425 |
0.358 |
|
| 2008 |
Pérez M, Baig I, Braña AF, Salas JA, Rohr J, Méndez C. Generation of new derivatives of the antitumor antibiotic mithramycin by altering the glycosylation pattern through combinatorial biosynthesis. Chembiochem : a European Journal of Chemical Biology. 9: 2295-304. PMID 18756551 DOI: 10.1002/Cbic.200800299 |
0.349 |
|
| 2008 |
Abdelfattah MS, Kharel MK, Hitron JA, Baig I, Rohr J. Moromycins A and B, isolation and structure elucidation of C-glycosylangucycline-type antibiotics from Streptomyces sp. KY002. Journal of Natural Products. 71: 1569-73. PMID 18666798 DOI: 10.1021/Np800281F |
0.352 |
|
| 2008 |
Ramos A, Lombó F, Braña AF, Rohr J, Méndez C, Salas JA. Biosynthesis of elloramycin in Streptomyces olivaceus requires glycosylation by enzymes encoded outside the aglycon cluster. Microbiology (Reading, England). 154: 781-8. PMID 18310024 DOI: 10.1099/Mic.0.2007/014035-0 |
0.364 |
|
| 2008 |
Olano C, Abdelfattah MS, Gullón S, Braña AF, Rohr J, Méndez C, Salas JA. Glycosylated derivatives of steffimycin: insights into the role of the sugar moieties for the biological activity. Chembiochem : a European Journal of Chemical Biology. 9: 624-33. PMID 18224649 DOI: 10.1002/Cbic.200700610 |
0.387 |
|
| 2008 |
Baig I, Perez M, Braña AF, Gomathinayagam R, Damodaran C, Salas JA, Méndez C, Rohr J. Mithramycin analogues generated by combinatorial biosynthesis show improved bioactivity. Journal of Natural Products. 71: 199-207. PMID 18197601 DOI: 10.1021/Np0705763 |
0.365 |
|
| 2007 |
Kharel MK, Zhu L, Liu T, Rohr J. Multi-oxygenase complexes of the gilvocarcin and jadomycin biosyntheses. Journal of the American Chemical Society. 129: 3780-1. PMID 17346045 DOI: 10.1021/Ja0680515 |
0.416 |
|
| 2007 |
Zhu L, Luzhetskyy A, Luzhetska M, Mattingly C, Adams V, Bechthold A, Rohr J. Generation of new landomycins with altered saccharide patterns through over-expression of the glycosyltransferase gene lanGT3 in the biosynthetic gene cluster of landomycin A in Streptomyces cyanogenus S-136. Chembiochem : a European Journal of Chemical Biology. 8: 83-8. PMID 17139690 DOI: 10.1002/Cbic.200600360 |
0.391 |
|
| 2006 |
Rohr J. Cryptophycin anticancer drugs revisited. Acs Chemical Biology. 1: 747-50. PMID 17240971 DOI: 10.1021/Cb6004678 |
0.324 |
|
| 2006 |
Baig I, Kharel M, Kobylyanskyy A, Zhu L, Rebets Y, Ostash B, Luzhetskyy A, Bechthold A, Fedorenko VA, Rohr J. On the acceptor substrate of C-glycosyltransferase UrdGT2: three prejadomycin C-Glycosides from an engineered mutant of Streptomyces globisporus 1912 DeltalndE(urdGT2). Angewandte Chemie (International Ed. in English). 45: 7842-6. PMID 17061307 DOI: 10.1002/Anie.200603176 |
0.333 |
|
| 2006 |
Pérez M, Lombó F, Baig I, Braña AF, Rohr J, Salas JA, Méndez C. Combinatorial biosynthesis of antitumor deoxysugar pathways in Streptomyces griseus: Reconstitution of "unnatural natural gene clusters" for the biosynthesis of four 2,6-D-dideoxyhexoses. Applied and Environmental Microbiology. 72: 6644-52. PMID 17021216 DOI: 10.1128/Aem.01266-06 |
0.34 |
|
| 2006 |
Garrido LM, Lombó F, Baig I, Nur-E-Alam M, Furlan RL, Borda CC, Braña A, Méndez C, Salas JA, Rohr J, Padilla G. Insights in the glycosylation steps during biosynthesis of the antitumor anthracycline cosmomycin: characterization of two glycosyltransferase genes. Applied Microbiology and Biotechnology. 73: 122-31. PMID 16810496 DOI: 10.1007/S00253-006-0453-Z |
0.37 |
|
| 2006 |
Liu T, Kharel MK, Fischer C, McCormick A, Rohr J. Inactivation of gilGT, encoding a C-glycosyltransferase, and gilOIII, encoding a P450 enzyme, allows the details of the late biosynthetic pathway to gilvocarcin V to be delineated. Chembiochem : a European Journal of Chemical Biology. 7: 1070-7. PMID 16795121 DOI: 10.1002/Cbic.200600031 |
0.373 |
|
| 2006 |
Gullón S, Olano C, Abdelfattah MS, Braña AF, Rohr J, Méndez C, Salas JA. Isolation, characterization, and heterologous expression of the biosynthesis gene cluster for the antitumor anthracycline steffimycin. Applied and Environmental Microbiology. 72: 4172-83. PMID 16751529 DOI: 10.1128/Aem.00734-06 |
0.343 |
|
| 2006 |
Albertini V, Jain A, Vignati S, Napoli S, Rinaldi A, Kwee I, Nur-e-Alam M, Bergant J, Bertoni F, Carbone GM, Rohr J, Catapano CV. Novel GC-rich DNA-binding compound produced by a genetically engineered mutant of the mithramycin producer Streptomyces argillaceus exhibits improved transcriptional repressor activity: implications for cancer therapy. Nucleic Acids Research. 34: 1721-34. PMID 16571899 DOI: 10.1093/Nar/Gkl063 |
0.319 |
|
| 2005 |
Gibson M, Nur-e-alam M, Lipata F, Oliveira MA, Rohr J. Characterization of kinetics and products of the Baeyer-Villiger oxygenase MtmOIV, the key enzyme of the biosynthetic pathway toward the natural product anticancer drug mithramycin from Streptomyces argillaceus. Journal of the American Chemical Society. 127: 17594-5. PMID 16351075 DOI: 10.1021/Ja055750T |
0.394 |
|
| 2005 |
Salas AP, Zhu L, Sánchez C, Braña AF, Rohr J, Méndez C, Salas JA. Deciphering the late steps in the biosynthesis of the anti-tumour indolocarbazole staurosporine: sugar donor substrate flexibility of the StaG glycosyltransferase. Molecular Microbiology. 58: 17-27. PMID 16164546 DOI: 10.1111/J.1365-2958.2005.04777.X |
0.343 |
|
| 2005 |
Chen YH, Wang CC, Greenwell L, Rix U, Hoffmeister D, Vining LC, Rohr J, Yang KQ. Functional analyses of oxygenases in jadomycin biosynthesis and identification of JadH as a bifunctional oxygenase/dehydrase Journal of Biological Chemistry. 280: 22508-22514. PMID 15817470 DOI: 10.1074/Jbc.M414229200 |
0.361 |
|
| 2005 |
Luzhetskyy A, Zhu L, Gibson M, Fedoryshyn M, Dürr C, Hofmann C, Hoffmeister D, Ostash B, Mattingly C, Adams V, Fedorenko V, Rohr J, Bechthold A. Generation of novel landomycins M and O through targeted gene disruption. Chembiochem : a European Journal of Chemical Biology. 6: 675-8. PMID 15812784 DOI: 10.1002/Cbic.200400316 |
0.331 |
|
| 2005 |
Rix U, Wang C, Chen Y, Lipata FM, Rix LLR, Greenwell LM, Vining LC, Yang K, Rohr J. The oxidative ring cleavage in jadomycin biosynthesis: A multistep oxygenation cascade in a biosynthetic black box Chembiochem. 6: 838-845. PMID 15776503 DOI: 10.1002/Cbic.200400395 |
0.389 |
|
| 2005 |
Pérez M, Lombó F, Zhu L, Gibson M, Braña AF, Rohr J, Salas JA, Méndez C. Combining sugar biosynthesis genes for the generation of L- and D-amicetose and formation of two novel antitumor tetracenomycins. Chemical Communications (Cambridge, England). 1604-6. PMID 15770274 DOI: 10.1039/B417815G |
0.33 |
|
| 2005 |
Zhu L, Ostash B, Rix U, Nur-E-Alam M, Mayers A, Luzhetskyy A, Mendez C, Salas JA, Bechthold A, Fedorenko V, Rohr J. Identification of the function of gene lndM2 encoding a bifunctional oxygenase-reductase involved in the biosynthesis of the antitumor antibiotic landomycin E by Streptomyces globisporus 1912 supports the originally assigned structure for landomycinone. The Journal of Organic Chemistry. 70: 631-8. PMID 15651811 DOI: 10.1021/Jo0483623 |
0.384 |
|
| 2005 |
Sánchez C, Zhu L, Braña AF, Salas AP, Rohr J, Méndez C, Salas JA. Combinatorial biosynthesis of antitumor indolocarbazole compounds. Proceedings of the National Academy of Sciences of the United States of America. 102: 461-6. PMID 15625109 DOI: 10.1073/Pnas.0407809102 |
0.377 |
|
| 2004 |
Lombó F, Gibson M, Greenwell L, Braña AF, Rohr J, Salas JA, Méndez C. Engineering biosynthetic pathways for deoxysugars: branched-chain sugar pathways and derivatives from the antitumor tetracenomycin. Chemistry & Biology. 11: 1709-18. PMID 15610855 DOI: 10.1016/J.Chembiol.2004.10.007 |
0.356 |
|
| 2004 |
Luzhetskyy A, Liu T, Fedoryshyn M, Ostash B, Fedorenko V, Rohr J, Bechthold A. Function of lanGT3, a glycosyltransferase gene involved in landomycin A biosynthesis. Chembiochem : a European Journal of Chemical Biology. 5: 1567-70. PMID 15515090 DOI: 10.1002/Cbic.200400123 |
0.328 |
|
| 2004 |
Liu T, Fischer C, Beninga C, Rohr J. Oxidative rearrangement processes in the biosynthesis of gilvocarcin V. Journal of the American Chemical Society. 126: 12262-3. PMID 15453748 DOI: 10.1021/Ja0467521 |
0.371 |
|
| 2004 |
Menéndez N, Nur-E-Alam M, Braña AF, Rohr J, Salas JA, Méndez C. Tailoring modification of deoxysugars during biosynthesis of the antitumour drug chromomycin A by Streptomyces griseus ssp. griseus. Molecular Microbiology. 53: 903-15. PMID 15255901 DOI: 10.1111/J.1365-2958.2004.04166.X |
0.361 |
|
| 2004 |
Pérez-Zúñiga FJ, Seco EM, Cuesta T, Degenhardt F, Rohr J, Vallín C, Iznaga Y, Pérez ME, González L, Malpartida F. CE-108, a new macrolide tetraene antibiotic. The Journal of Antibiotics. 57: 197-204. PMID 15152805 DOI: 10.7164/Antibiotics.57.197 |
0.323 |
|
| 2004 |
Ostash B, Rix U, Rix LL, Liu T, Lombo F, Luzhetskyy A, Gromyko O, Wang C, Braña AF, Méndez C, Salas JA, Fedorenko V, Rohr J. Generation of new landomycins by combinatorial biosynthetic manipulation of the LndGT4 gene of the landomycin E cluster in S. globisporus. Chemistry & Biology. 11: 547-55. PMID 15123249 DOI: 10.1016/J.Chembiol.2004.03.011 |
0.377 |
|
| 2004 |
Menéndez N, Nur-e-Alam M, Braña AF, Rohr J, Salas JA, Méndez C. Biosynthesis of the antitumor chromomycin A3 in Streptomyces griseus: analysis of the gene cluster and rational design of novel chromomycin analogs. Chemistry & Biology. 11: 21-32. PMID 15112992 DOI: 10.1016/J.Chembiol.2003.12.011 |
0.318 |
|
| 2003 |
Remsing LL, Bahadori HR, Carbone GM, McGuffie EM, Catapano CV, Rohr J. Inhibition of c-src transcription by mithramycin: structure-activity relationships of biosynthetically produced mithramycin analogues using the c-src promoter as target. Biochemistry. 42: 8313-24. PMID 12846580 DOI: 10.1021/Bi034091Z |
0.332 |
|
| 2003 |
Fischer C, Lipata F, Rohr J. The complete gene cluster of the antitumor agent gilvocarcin V and its implication for the biosynthesis of the gilvocarcins. Journal of the American Chemical Society. 125: 7818-9. PMID 12822997 DOI: 10.1021/Ja034781Q |
0.389 |
|
| 2003 |
Remsing LL, González AM, Nur-e-Alam M, Fernández-Lozano MJ, Braña AF, Rix U, Oliveira MA, Méndez C, Salas JA, Rohr J. Mithramycin SK, a novel antitumor drug with improved therapeutic index, mithramycin SA, and demycarosyl-mithramycin SK: three new products generated in the mithramycin producer Streptomyces argillaceus through combinatorial biosynthesis. Journal of the American Chemical Society. 125: 5745-53. PMID 12733914 DOI: 10.1021/Ja034162H |
0.378 |
|
| 2003 |
Hoffmeister D, Dräger G, Ichinose K, Rohr J, Bechthold A. The C-Glycosyltransferase UrdGT2 is unselective toward d- and l-configured nucleotide-bound rhodinoses. Journal of the American Chemical Society. 125: 4678-9. PMID 12696864 DOI: 10.1021/Ja029645K |
0.351 |
|
| 2003 |
Rix U, Remsing LL, Hoffmeister D, Bechthold A, Rohr J. Urdamycin L: a novel metabolic shunt product that provides evidence for the role of the urdM gene in the urdamycin A biosynthetic pathway of Streptomyces fradiae TU 2717. Chembiochem : a European Journal of Chemical Biology. 4: 109-11. PMID 12512084 DOI: 10.1002/Cbic.200390002 |
0.321 |
|
| 2002 |
Fischer C, Rodríguez L, Patallo EP, Lipata F, Braña AF, Méndez C, Salas JA, Rohr J. Digitoxosyltetracenomycin C and glucosyltetracenomycin C, two novel elloramycin analogues obtained by exploring the sugar donor substrate specificity of glycosyltransferase ElmGT. Journal of Natural Products. 65: 1685-9. PMID 12444703 DOI: 10.1021/Np020112Z |
0.355 |
|
| 2002 |
Méndez C, Künzel E, Lipata F, Lombó F, Cotham W, Walla M, Bearden DW, Braña AF, Salas JA, Rohr J. Oviedomycin, an unusual angucyclinone encoded by genes of the oleandomycin-producer Streptomyces antibioticus ATCC11891. Journal of Natural Products. 65: 779-82. PMID 12027768 DOI: 10.1021/Np010555N |
0.345 |
|
| 2002 |
Trefzer A, Blanco G, Remsing L, Künzel E, Rix U, Lipata F, Braña AF, Méndez C, Rohr J, Bechthold A, Salas JA. Rationally designed glycosylated premithramycins: hybrid aromatic polyketides using genes from three different biosynthetic pathways. Journal of the American Chemical Society. 124: 6056-62. PMID 12022840 DOI: 10.1021/Ja017385L |
0.39 |
|
| 2002 |
Sánchez C, Butovich IA, Braña AF, Rohr J, Méndez C, Salas JA. The biosynthetic gene cluster for the antitumor rebeccamycin: characterization and generation of indolocarbazole derivatives. Chemistry & Biology. 9: 519-31. PMID 11983340 DOI: 10.1016/S1074-5521(02)00126-6 |
0.344 |
|
| 2002 |
Macky TA, Oelkers C, Rix U, Heredia ML, Künzel E, Wimberly M, Rohrer B, Crosson CE, Rohr J. Synthesis, pharmacokinetics, efficacy, and rat retinal toxicity of a novel mitomycin C-triamcinolone acetonide conjugate. Journal of Medicinal Chemistry. 45: 1122-7. PMID 11855992 DOI: 10.1021/Jm010511B |
0.31 |
|
| 2002 |
Remsing LL, Garcia-Bernardo J, Gonzalez A, Künzel E, Rix U, Braña AF, Bearden DW, Méndez C, Salas JA, Rohr J. Ketopremithramycins and ketomithramycins, four new aureolic acid-type compounds obtained upon inactivation of two genes involved in the biosynthesis of the deoxysugar moieties of the antitumor drug mithramycin by Streptomyces argillaceus, reveal novel insights into post-PKS tailoring steps of the mithramycin biosynthetic pathway. Journal of the American Chemical Society. 124: 1606-14. PMID 11853433 DOI: 10.1021/Ja0105156 |
0.432 |
|
| 2002 |
Trefzer A, Fischer C, Stockert S, Westrich L, Künzel E, Girreser U, Rohr J, Bechthold A. Elucidation of the function of two glycosyltransferase genes (lanGT1 and lanGT4) involved in landomycin biosynthesis and generation of new oligosaccharide antibiotics. Chemistry & Biology. 8: 1239-52. PMID 11755402 DOI: 10.1016/S1074-5521(01)00091-6 |
0.383 |
|
| 2001 |
Patallo EP, Blanco G, Fischer C, Brana AF, Rohr J, Mendez C, Salas JA. Deoxysugar methylation during biosynthesis of the antitumor polyketide elloramycin by Streptomyces olivaceus. Characterization of three methyltransferase genes. The Journal of Biological Chemistry. 276: 18765-74. PMID 11376004 DOI: 10.1074/Jbc.M101225200 |
0.373 |
|
| 2001 |
Blanco G, Patallo EP, Braña AF, Trefzer A, Bechthold A, Rohr J, Méndez C, Salas JA. Identification of a sugar flexible glycosyltransferase from Streptomyces olivaceus, the producer of the antitumor polyketide elloramycin. Chemistry & Biology. 8: 253-63. PMID 11306350 DOI: 10.1016/S1074-5521(01)00010-2 |
0.392 |
|
| 2001 |
González A, Remsing LL, Lombó F, Fernández MJ, Prado L, Braña AF, Künzel E, Rohr J, Méndez C, Salas JA. The mtmVUC genes of the mithramycin gene cluster in Streptomyces argillaceus are involved in the biosynthesis of the sugar moieties. Molecular & General Genetics : Mgg. 264: 827-35. PMID 11254130 DOI: 10.1007/S004380000372 |
0.366 |
|
| 2000 |
Hoffmeister D, Ichinose K, Domann S, Faust B, Trefzer A, Dräger G, Kirschning A, Fischer C, Künzel E, Bearden DW, Rohr J, Bechthold A. The NDP-sugar co-substrate concentration and the enzyme expression level influence the substrate specificity of glycosyltransferases: Cloning and characterization of deoxysugar biosynthetic genes of the urdamycin biosynthetic gene cluster Chemistry and Biology. 7: 821-831. PMID 11094336 DOI: 10.1016/S1074-5521(00)00029-6 |
0.367 |
|
| 2000 |
Trefzer A, Hoffmeister D, Künzel E, Stockert S, Weitnauer G, Westrich L, Rix U, Fuchser J, Bindseil KU, Rohr J, Bechthold A. Function of glycosyltransferase genes involved in urdamycin A biosynthesis. Chemistry & Biology. 7: 133-42. PMID 10662691 DOI: 10.1016/S1074-5521(00)00079-X |
0.327 |
|
| 2000 |
Blanco G, Fernández E, Fernández MJ, Braña AF, Weissbach U, Künzel E, Rohr J, Méndez C, Salas JA. Characterization of two glycosyltransferases involved in early glycosylation steps during biosynthesis of the antitumor polyketide mithramycin by Streptomyces argillaceus. Molecular & General Genetics : Mgg. 262: 991-1000. PMID 10660060 DOI: 10.1007/Pl00008667 |
0.366 |
|
| 2000 |
Faust B, Hoffmeister D, Weitnauer G, Westrich L, Haag S, Schneider P, Decker H, Künzel E, Rohr J, Bechthold A. Two new tailoring enzymes, a glycosyltransferase and an oxygenase, involved in biosynthesis of the angucycline antibiotic urdamycin A in Streptomyces fradiae Tü2717. Microbiology (Reading, England). 146: 147-54. PMID 10658661 DOI: 10.1099/00221287-146-1-147 |
0.392 |
|
| 2000 |
Lozano MJ, Remsing LL, Quirós LM, Braña AF, Fernández E, Sánchez C, Méndez C, Rohr J, Salas JA. Characterization of two polyketide methyltransferases involved in the biosynthesis of the antitumor drug mithramycin by Streptomyces argillaceus. The Journal of Biological Chemistry. 275: 3065-74. PMID 10652287 DOI: 10.1074/Jbc.275.5.3065 |
0.349 |
|
| 1999 |
Prado L, Lombó F, Braña AF, Méndez C, Rohr J, Salas JA. Analysis of two chromosomal regions adjacent to genes for a type II polyketide synthase involved in the biosynthesis of the antitumor polyketide mithramycin in Streptomyces argillaceus. Molecular & General Genetics : Mgg. 261: 216-25. PMID 10102355 DOI: 10.1007/S004380050960 |
0.345 |
|
| 1999 |
Prado L, Fernández E, Weissbach U, Blanco G, Quirós LM, Braña AF, Méndez C, Rohr J, Salas JA. Oxidative cleavage of premithramycin B is one of the last steps in the biosynthesis of the antitumor drug mithramycin. Chemistry & Biology. 6: 19-30. PMID 9889148 DOI: 10.1016/S1074-5521(99)80017-9 |
0.301 |
|
| 1999 |
Künzel E, Faust B, Oelkers C, Weissbach U, Bearden DW, Weitnauer G, Westrich L, Bechthold A, Rohr J. Inactivation of the urdGT2 gene, which encodes a glycosyltransferase responsible for the C-glycosyltransfer of activated D-olivose, leads to formation of the novel urdamycins I, J, and K Journal of the American Chemical Society. 121: 11058-11062. DOI: 10.1021/Ja9915347 |
0.384 |
|
| 1999 |
Rohr J, Méndez C, Salas JA. The biosynthesis of aureolic acid group antibiotics Bioorganic Chemistry. 27: 41-54. DOI: 10.1006/Bioo.1998.1110 |
0.332 |
|
| 1998 |
Fernández E, Weissbach U, Sánchez Reillo C, Braña AF, Méndez C, Rohr J, Salas JA. Identification of two genes from Streptomyces argillaceus encoding glycosyltransferases involved in transfer of a disaccharide during biosynthesis of the antitumor drug mithramycin. Journal of Bacteriology. 180: 4929-37. PMID 9733697 DOI: 10.1128/Jb.180.18.4929-4937.1998 |
0.389 |
|
| 1997 |
Rohr J, Wohlert S, Oelkers C, Kirschning A, Ries M. Biosynthetic short activation of the 2,3,6-trideoxysugarl-rhodinose Chemical Communications. 973-974. DOI: 10.1039/A702125I |
0.305 |
|
| 1997 |
Krohn K, Rohr J. Angucyclines : Total Syntheses, New Structures, And Biosynthetic Studies Of An Emerging New Class Of Antibiotics Topics in Current Chemistry. 188: 127-195. DOI: 10.1007/Bfb0119236 |
0.331 |
|
| 1997 |
Kirschning A, Bechthold AFW, Rohr J. Chemical and biochemical aspects of deoxysugars and deoxysugar oligosaccharides Topics in Current Chemistry. 188: 1-84. DOI: 10.1007/Bfb0119234 |
0.355 |
|
| 1997 |
Künzel E, Wohlert SE, Beninga C, Haag S, Decker H, Hutchinson CR, Blanco G, Mendez C, Salas JA, Rohr J. Tetracenomycin M, a novel genetically engineered tetracenomycin resulting from a combination of mithramycin and tetracenomycin biosynthetic genes Chemistry - a European Journal. 3: 1675-1678. DOI: 10.1002/Chem.19970031017 |
0.386 |
|
| 1997 |
Rohr J. Biosynthesis of Taxol Angewandte Chemie (International Edition in English). 36: 2190-2195. DOI: 10.1002/Anie.199721901 |
0.328 |
|
| 1996 |
Blum S, Groth I, Rohr J, Fielder HP. Biosynthetic capacities of actinomycetes. 5. Dioxolides, novel secondary metabolites from Streptomyces tendae. Journal of Basic Microbiology. 36: 19-25. PMID 8819841 DOI: 10.1002/Jobm.3620360105 |
0.309 |
|
| 1995 |
Decker H, Rohr J, Motamedi H, Zähner H, Hutchinson CR. Identification of Streptomyces olivaceus Tü 2353 genes involved in the production of the polyketide elloramycin. Gene. 166: 121-6. PMID 8529875 DOI: 10.1016/0378-1119(95)00573-7 |
0.33 |
|
| 1995 |
Rohr J. Combinatorial Biosynthesis–An Approach in the Near Future? Angewandte Chemie International Edition in English. 34: 881-885. DOI: 10.1002/Anie.199508811 |
0.34 |
|
| 1990 |
Henkel T, Rohr J, Beale JM, Schwenen L. Landomycins, new angucycline antibiotics from Streptomyces SP. I. Structural studies on landomycins A~D Journal of Antibiotics. 43: 492-503. PMID 2358402 DOI: 10.7164/Antibiotics.43.492 |
0.351 |
|
| 1990 |
Rohr J, Zeeck A. Structure-activity relationships of elloramycin and tetracenomycin C Journal of Antibiotics. 43: 1169-1178. PMID 2211379 DOI: 10.7164/Antibiotics.43.1169 |
0.35 |
|
| 1989 |
Henkel T, Ciesiolka T, Rohr J, Zeeck A. Urdamycins, new angucycline antibiotics from streptomyces fradiae. V. Derivatives of urdamycin A Journal of Antibiotics. 42: 299-311. PMID 2925521 DOI: 10.7164/Antibiotics.42.299 |
0.329 |
|
| 1989 |
Rohr J. Urdamycins, new angucycline antibiotics from Streptomyces fradiae. VI. Structure elucidation and biosynthetic investigations on urdamycin H Journal of Antibiotics. 42: 1482-1488. PMID 2808135 DOI: 10.7164/Antibiotics.42.1482 |
0.383 |
|
| 1989 |
Rohr J, Beale JM, Floss HG. Urdamycins, new angucycline antibiotics from Streptomyces fradiae. IV. Biosynthetic studies of urdamycins A-D. The Journal of Antibiotics. 42: 1151-7. PMID 2753820 DOI: 10.7164/Antibiotics.42.1151 |
0.335 |
|
| 1988 |
Rohr J, Zeeck A, Floss HG. Urdamycins, new angucycline antibiotics from Streptomyces fradiae. III. The structures of urdamycins C and D. The Journal of Antibiotics. 41: 126-9. PMID 3346183 DOI: 10.7164/Antibiotics.41.126 |
0.329 |
|
| 1988 |
Rohr J, Eick S, Zeeck A, Reuschenbach P, Zähner H, Fiedler H. Metabolic products of microorganisms. 249. Tetracenomycins B3 and D3, key intermediates of the elloramycin and tetracenomycin C biosynthesis. The Journal of Antibiotics. 41: 1066-1073. PMID 3170342 DOI: 10.7164/Antibiotics.41.1066 |
0.348 |
|
| 1987 |
Rohr J, Zeeck A. Metabolic products of microorganisms. Urdamycins, new angucycline antibiotics from Streptomyces fradiae. II. Structural studies of urdamycins B to F Journal of Antibiotics. 40: 459-467. PMID 3583915 DOI: 10.7164/Antibiotics.40.459 |
0.344 |
|
| 1986 |
Drautz H, Zahner H, Rohr J, Zeeck A. Metabolic products of microorganisms. 234. Urdamycins, new angucycline antibiotics from Streptomyces fradiae. I. Isolation, characterization and biological properties Journal of Antibiotics. 39: 1657-1669. PMID 3818439 DOI: 10.7164/Antibiotics.39.1657 |
0.377 |
|
| 1985 |
Drautz H, Reuschenbach P, Zahner H, Rohr J, Zeeck A. Metabolic products of microorganisms. 225 Elloramycin, a new anthracycline-like antibiotic from Streptomyces olivaceus. Isolation, characterization, structure and biological properties Journal of Antibiotics. 38: 1291-1301. PMID 3840789 DOI: 10.7164/Antibiotics.38.1291 |
0.384 |
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