| Year |
Citation |
Score |
| 2023 |
Thoden JB, Benin BM, Priebe A, Shin WS, Muthyala R, Sham YY, Holden HM. Characterization of a novel inhibitor for the New Delhi metallo-β-lactamase-4: implications for drug design and combating bacterial drug resistance. The Journal of Biological Chemistry. 105135. PMID 37549809 DOI: 10.1016/j.jbc.2023.105135 |
0.764 |
|
| 2023 |
Sahu BS, Razzoli M, McGonigle S, Pallais JP, Nguyen ME, Sadahiro M, Jiang C, Lin WJ, Kelley KA, Rodriguez P, Mansk R, Cero C, Caviola G, Palanza P, Rao L, ... ... Sham YY, et al. Targeted and selective knockout of the TLQP-21 neuropeptide unmasks its unique role in energy homeostasis. Molecular Metabolism. 101781. PMID 37482186 DOI: 10.1016/j.molmet.2023.101781 |
0.552 |
|
| 2023 |
Hillyer T, Benin BM, Sun C, Aguirre N, Willard B, Sham YY, Shin WS. A novel strategy to characterize the pattern of β-lactam antibiotic-induced drug resistance in Acinetobacter baumannii. Scientific Reports. 13: 9177. PMID 37280269 DOI: 10.1038/s41598-023-36475-9 |
0.757 |
|
| 2023 |
Sahu BS, Razzoli M, McGonigle S, Pallais JP, Nguyen ME, Sadahiro M, Jiang C, Lin WJ, Kelley KA, Rodriguez P, Mansk R, Cero C, Caviola G, Palanza P, Rao L, ... ... Sham YY, et al. Targeted and selective knockout of the TLQP-21 neuropeptide unmasks its unique role in energy homeostasis. Biorxiv : the Preprint Server For Biology. PMID 36993202 DOI: 10.1101/2023.03.23.532619 |
0.571 |
|
| 2023 |
Sahu BS, Nguyen ME, Rodriguez P, Pallais JP, Ghosh V, Razzoli M, Sham YY, Salton SR, Bartolomucci A. Correction: The molecular identity of the TLQP-21 peptide receptor. Cellular and Molecular Life Sciences : Cmls. 80: 66. PMID 36806028 DOI: 10.1007/s00018-023-04718-7 |
0.544 |
|
| 2023 |
Hillyer T, Benin BM, Sun C, Aguirre N, Willard B, Sham YY, Shin WS. A novel strategy to characterize the pattern of β-lactam antibiotic-induced drug resistance in Acinetobacter baumannii. Research Square. PMID 36711967 DOI: 10.21203/rs.3.rs-2359505/v1 |
0.759 |
|
| 2021 |
Sahu BS, Nguyen ME, Rodriguez P, Pallais JP, Ghosh V, Razzoli M, Sham YY, Salton SR, Bartolomucci A. The molecular identity of the TLQP-21 peptide receptor. Cellular and Molecular Life Sciences : Cmls. PMID 34626205 DOI: 10.1007/s00018-021-03944-1 |
0.567 |
|
| 2021 |
Shin WS, Nguyen ME, Bergstrom A, Jennings IR, Crowder MW, Muthyala R, Sham YY. Fragment based screening and hit-based substructure search: Rapid discovery of 8-hydroxyquinoline-7-carboxylic acid as a low-cytotoxic, nanomolar metallo β-lactamase inhibitor. Chemical Biology & Drug Design. PMID 34148302 DOI: 10.1111/cbdd.13912 |
0.764 |
|
| 2021 |
Ampudia-Mesias E, Puerta-Martinez F, Bridges M, Zellmer D, Janeiro A, Strokes M, Sham YY, Taher A, Castro MG, Moertel CL, Pluhar GE, Olin MR. Correction to: CD200 Immune-Checkpoint Peptide Elicits an Anti-glioma Response Through the DAP10 Signaling Pathway. Neurotherapeutics : the Journal of the American Society For Experimental Neurotherapeutics. PMID 33929711 DOI: 10.1007/s13311-021-01062-1 |
0.737 |
|
| 2021 |
Ramirez-Mondragon CA, Nguyen ME, Milicaj J, Hassan BA, Tucci FJ, Muthyala R, Gao J, Taylor EA, Sham YY. Conserved Conformational Hierarchy across Functionally Divergent Glycosyltransferases of the GT-B Structural Superfamily as Determined from Microsecond Molecular Dynamics. International Journal of Molecular Sciences. 22. PMID 33924837 DOI: 10.3390/ijms22094619 |
0.584 |
|
| 2021 |
Ampudia-Mesias E, Puerta-Martinez F, Bridges M, Zellmer D, Janeiro A, Strokes M, Sham YY, Taher A, Castro MG, Moertel CL, Pluhar GE, Olin MR. CD200 Immune-Checkpoint Peptide Elicits an Anti-glioma Response Through the DAP10 Signaling Pathway. Neurotherapeutics : the Journal of the American Society For Experimental Neurotherapeutics. PMID 33829411 DOI: 10.1007/s13311-021-01038-1 |
0.756 |
|
| 2021 |
Ortiz Cordero C, Magli A, Dhoke N, Kuebler T, Oliveira NA, Zhou H, Sham YY, Bang AG, Perlingeiro RC. NAD+ enhances ribitol and ribose rescue of α-dystroglycan functional glycosylation in human FKRP-mutant myotubes. Elife. 10. PMID 33513091 DOI: 10.7554/eLife.65443 |
0.744 |
|
| 2020 |
Cote JM, Hecht CJS, Patel KR, Ramirez-Mondragon CA, Sham YY, Taylor EA. Opposites Attract: Heptosyltransferase I Conformational Changes Induced by Interactions between Substrate and Positively Charged Residues. Biochemistry. PMID 32011131 DOI: 10.1021/Acs.Biochem.9B01005 |
0.351 |
|
| 2019 |
Sahu BS, Rodriguez P, Nguyen ME, Han R, Cero C, Razzoli M, Piaggi P, Laskowski LJ, Pavlicev M, Muglia L, Mahata SK, O'Grady S, McCorvy JD, Baier LJ, Sham YY, et al. Peptide/Receptor Co-evolution Explains the Lipolytic Function of the Neuropeptide TLQP-21. Cell Reports. 28: 2567-2580.e6. PMID 31484069 DOI: 10.1016/J.Celrep.2019.07.101 |
0.622 |
|
| 2019 |
Zafar S, Nguyen ME, Muthyala R, Jabeen I, Sham YY. Modeling and Simulation of GAT1: A Mechanistic Investigation of the GABA Transport Process. Computational and Structural Biotechnology Journal. 17: 61-69. PMID 30619541 DOI: 10.1016/J.Csbj.2018.12.003 |
0.566 |
|
| 2018 |
Seiler CL, Fernandez J, Koerperich Z, Andersen MP, Kotandeniya D, Nguyen ME, Sham YY, Tretyakova NY. Maintenance DNA methyltransferase activity in the presence of oxidized forms of 5-methylcytosine: Structural basis for TET-mediated DNA demethylation. Biochemistry. PMID 30230311 DOI: 10.1021/Acs.Biochem.8B00683 |
0.577 |
|
| 2018 |
Cong H, Zhao X, Castle BT, Pomeroy EJ, Zhou B, Lee J, Wang Y, Bian T, Miao Z, Zhang W, Sham YY, Odde DJ, Eckfeldt CE, Xing C, Zhuang C. An indole-chalcone inhibits multidrug-resistant cancer cell growth by targeting microtubules. Molecular Pharmaceutics. PMID 30048137 DOI: 10.1021/Acs.Molpharmaceut.8B00359 |
0.324 |
|
| 2018 |
Zhou Y, Wu Y, Pokholenko O, Grimsrud M, Sham Y, Papper V, Marks R, Steele T. Aptamer adaptive binding assessed by stilbene photoisomerization towards regenerating aptasensors Sensors and Actuators B: Chemical. 257: 245-255. DOI: 10.1016/J.Snb.2017.10.135 |
0.723 |
|
| 2017 |
Muthyala R, Shin WS, Sham YY, Bergstrom A, Crowder MW, Bonomo RA. Discovery of 1-hydroxypyridine-2(1H)-thione-6-carboxylic acid as a first-in-class low-cytotoxic nanomolar metallo -lactamase inhibitor. Chemmedchem. PMID 28482143 DOI: 10.1002/Cmdc.201700182 |
0.715 |
|
| 2017 |
Cote JM, Ramirez-Mondragon CA, Siegel ZS, Czyzyk DJ, Gao J, Sham YY, Mukerji I, Taylor EA. The Stories Tryptophans Tell: Exploring Protein Dynamics of Heptosyltransferase I from Escherichia coli. Biochemistry. PMID 28098447 DOI: 10.1021/Acs.Biochem.6B00850 |
0.371 |
|
| 2015 |
Muthyala R, Shin WS, Xie J, Sham YY. Discovery of 1-hydroxypyridine-2-thiones as selective histone deacetylase inhibitors and their potential application for treating leukemia. Bioorganic & Medicinal Chemistry Letters. 25: 4320-4. PMID 26264503 DOI: 10.1016/J.Bmcl.2015.07.065 |
0.696 |
|
| 2014 |
Zhuang C, Sheng C, Shin WS, Wu Y, Li J, Yao J, Dong G, Zhang W, Sham YY, Miao Z, Zhang W. A novel drug discovery strategy: mechanistic investigation of an enantiomeric antitumor agent targeting dual p53 and NF-κB pathways. Oncotarget. 5: 10830-9. PMID 25350970 DOI: 10.18632/Oncotarget.2521 |
0.689 |
|
| 2014 |
Thompson BR, Houang EM, Sham YY, Metzger JM. Molecular determinants of cardiac myocyte performance as conferred by isoform-specific TnI residues. Biophysical Journal. 106: 2105-14. PMID 24853739 DOI: 10.1016/J.Bpj.2014.04.017 |
0.305 |
|
| 2014 |
Muthyala R, Rastogi N, Shin WS, Peterson ML, Sham YY. Cell permeable vanX inhibitors as vancomycin re-sensitizing agents Bioorganic and Medicinal Chemistry Letters. 24: 2535-2538. PMID 24751446 DOI: 10.1016/J.Bmcl.2014.03.097 |
0.703 |
|
| 2014 |
Zhuang C, Narayanapillai S, Zhang W, Sham YY, Xing C. Rapid identification of Keap1-Nrf2 small-molecule inhibitors through structure-based virtual screening and hit-based substructure search. Journal of Medicinal Chemistry. 57: 1121-6. PMID 24417449 DOI: 10.1021/Jm4017174 |
0.31 |
|
| 2014 |
Zhou W, Chen F, Klyachkin Y, Sham YY, Geraghty RJ. Mutations in the amino terminus of herpes simplex virus type 1 gL can reduce cell-cell fusion without affecting gH/gL trafficking. Journal of Virology. 88: 739-44. PMID 24155377 DOI: 10.1128/Jvi.02383-13 |
0.313 |
|
| 2013 |
Ferreira R, Artali R, Benoit A, Gargallo R, Eritja R, Ferguson DM, Sham YY, Mazzini S. Structure and stability of human telomeric G-quadruplex with preclinical 9-amino acridines. Plos One. 8: e57701. PMID 23554865 DOI: 10.1371/Journal.Pone.0057701 |
0.318 |
|
| 2012 |
Sirivolu VR, Vernekar SK, Marchand C, Naumova A, Chergui A, Renaud A, Stephen AG, Chen F, Sham YY, Pommier Y, Wang Z. 5-Arylidenethioxothiazolidinones as inhibitors of tyrosyl-DNA phosphodiesterase I. Journal of Medicinal Chemistry. 55: 8671-84. PMID 23006064 DOI: 10.1021/Jm3008773 |
0.404 |
|
| 2012 |
Thompson BR, Houang E, Sham Y, Metzger JM. Molecular Mechanisms of A164H cTnI Biophysical Journal. 102: 560a-561a. DOI: 10.1016/J.Bpj.2011.11.3052 |
0.302 |
|
| 2010 |
Chen L, Petrelli R, Gao G, Wilson DJ, McLean GT, Jayaram HN, Sham YY, Pankiewicz KW. Dual inhibitors of inosine monophosphate dehydrogenase and histone deacetylase based on a cinnamic hydroxamic acid core structure. Bioorganic & Medicinal Chemistry. 18: 5950-64. PMID 20650640 DOI: 10.1016/J.Bmc.2010.06.081 |
0.326 |
|
| 2010 |
Chen L, Wilson DJ, Xu Y, Aldrich CC, Felczak K, Sham YY, Pankiewicz KW. Triazole-linked inhibitors of inosine monophosphate dehydrogenase from human and Mycobacterium tuberculosis. Journal of Medicinal Chemistry. 53: 4768-78. PMID 20491506 DOI: 10.1021/Jm100424M |
0.302 |
|
| 2010 |
Lu D, Sham YY, Vince R. Design, asymmetric synthesis, and evaluation of pseudosymmetric sulfoximine inhibitors against HIV-1 protease. Bioorganic & Medicinal Chemistry. 18: 2037-48. PMID 20138769 DOI: 10.1016/J.Bmc.2010.01.020 |
0.301 |
|
| 2009 |
Cohen DN, Sham YY, Haugstad GD, Xiang Y, Rossmann MG, Anderson DL, Popham DL. Shared catalysis in virus entry and bacterial cell wall depolymerization. Journal of Molecular Biology. 387: 607-18. PMID 19361422 DOI: 10.1016/J.Jmb.2009.02.001 |
0.33 |
|
| 2007 |
Xing C, Wang L, Tang X, Sham YY. Development of selective inhibitors for anti-apoptotic Bcl-2 proteins from BHI-1. Bioorganic & Medicinal Chemistry. 15: 2167-76. PMID 17227711 DOI: 10.1016/J.Bmc.2006.12.020 |
0.309 |
|
| 2007 |
Ma L, Sham YY, Walters KJ, Towle HC. A critical role for the loop region of the basic helix-loop-helix/leucine zipper protein Mlx in DNA binding and glucose-regulated transcription. Nucleic Acids Research. 35: 35-44. PMID 17148476 DOI: 10.1093/Nar/Gkl987 |
0.303 |
|
| 2002 |
Sham YY, Ma B, Tsai CJ, Nussinov R. Thermal unfolding molecular dynamics simulation of Escherichia coli dihydrofolate reductase: Thermal stability of protein domains and unfolding pathway Proteins: Structure, Function and Genetics. 46: 308-320. PMID 11835506 DOI: 10.1002/Prot.10040 |
0.469 |
|
| 2001 |
Tsai CJ, Buyong M, Sham YY, Kumar S, Nussinov R. Structured disorder and conformational selection Proteins: Structure, Function and Genetics. 44: 418-427. PMID 11484219 DOI: 10.1002/Prot.1107 |
0.442 |
|
| 2001 |
Kumar S, Sham YY, Tsai CJ, Nussinov R. Protein folding and function: The N-terminal fragment in adenylate kinase Biophysical Journal. 80: 2439-2454. PMID 11325743 DOI: 10.1016/S0006-3495(01)76213-3 |
0.466 |
|
| 2001 |
Sham YY, Ma B, Tsai CJ, Nussinov R. Molecular dynamics simulation of Escherichia coli dihydrofolate reductase and its protein fragments: relative stabilities in experiment and simulations. Protein Science : a Publication of the Protein Society. 10: 135-48. PMID 11266602 DOI: 10.1110/Ps.33301 |
0.441 |
|
| 2001 |
Tsai CJ, Ma B, Sham YY, Kumar S, Wolfson HJ, Nussinov R. A hierarchical, building-block-based computational scheme for protein structure prediction Ibm Journal of Research and Development. 45: 513-523. DOI: 10.1147/Rd.453.0513 |
0.426 |
|
| 2000 |
Villa J, Strajbl M, Glennon TM, Sham YY, Chu ZT, Warshel A. How important are entropic contributions to enzyme catalysis? Proceedings of the National Academy of Sciences of the United States of America. 97: 11899-904. PMID 11050223 DOI: 10.1073/Pnas.97.22.11899 |
0.585 |
|
| 2000 |
Sham YY, Chu ZT, Tao H, Warshel A. Examining methods for calculations of binding free energies: LRA, LIE, PDLD-LRA, and PDLD/S-LRA calculations of ligands binding to an HIV protease. Proteins. 39: 393-407. PMID 10813821 DOI: 10.1002/(Sici)1097-0134(20000601)39:4<393::Aid-Prot120>3.0.Co;2-H |
0.602 |
|
| 2000 |
Strajbl M, Sham YY, Villà J, Chu ZT, Warshel A. Calculations of Activation Entropies of Chemical Reactions in Solution Journal of Physical Chemistry B. 104: 4578-4584. DOI: 10.1021/Jp0003095 |
0.574 |
|
| 1999 |
Sham YY, Muegge I, Warshel A. Simulating proton translocations in proteins: probing proton transfer pathways in the Rhodobacter sphaeroides reaction center. Proteins. 36: 484-500. PMID 10450091 DOI: 10.1002/(Sici)1097-0134(19990901)36:4<484::Aid-Prot13>3.0.Co;2-R |
0.585 |
|
| 1998 |
Sham YY, Muegge I, Warshel A. The effect of protein relaxation on charge-charge interactions and dielectric constants of proteins. Biophysical Journal. 74: 1744-53. PMID 9545037 DOI: 10.1016/S0006-3495(98)77885-3 |
0.579 |
|
| 1998 |
Sham YY, Warshel A. The surface constraint all atom model provides size independent results in calculations of hydration free energies Journal of Chemical Physics. 109: 7940-7944. DOI: 10.1063/1.477441 |
0.572 |
|
| 1997 |
Sham YY, Chu ZT, Warshel A. Consistent Calculations of pKa's of Ionizable Residues in Proteins: Semi-microscopic and Microscopic Approaches The Journal of Physical Chemistry B. 101: 4458-4472. DOI: 10.1021/Jp963412W |
0.583 |
|
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