Eleftherios P. Diamandis - Publications

Affiliations: 
Laboratory Medicine and Pathobiology University of Toronto, Toronto, ON, Canada 
Area:
Molecular Biology, Biochemistry

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Year Citation  Score
2024 Chatanaka MK, Prassas I, Diamandis EP. Diagnostic and progression biomarkers in cerebrospinal fluid of Alzheimer's disease patients. Bmc Medicine. 22: 60. PMID 38331825 DOI: 10.1186/s12916-024-03270-w  0.595
2024 Vasudevan Nampoothiri R, Avery L, Pasic I, Prassas I, Diamandis E, Michelis FV. Multiplex proteomics in the identification of potential biomarkers of very severe sinusoidal obstruction syndrome/veno-occlusive disease (SOS/VOD) in allogeneic hematopoietic cell transplant patients treated with defibrotide. Acta Haematologica. PMID 38330921 DOI: 10.1159/000535706  0.626
2023 Chatanaka MK, Avery LM, Pasic MD, Sithravadivel S, Rotstein D, Demos C, Cohen R, Gorham T, Wang M, Stengelin M, Mathew A, Wohlstadter J, Prassas I, Diamandis EP. The relationship between serum astroglial and neuronal markers and AQP4 and MOG autoantibodies. Research Square. PMID 38077014 DOI: 10.21203/rs.3.rs-3659922/v1  0.592
2023 Sohaei D, Thebault S, Avery LM, Batruch I, Lam B, Xu W, Saadeh RS, Scarisbrick IA, Diamandis EP, Prassas I, Freedman MS. Cerebrospinal fluid camk2a levels at baseline predict long-term progression in multiple sclerosis. Clinical Proteomics. 20: 33. PMID 37644477 DOI: 10.1186/s12014-023-09418-9  0.588
2023 Janket SJ, Fraser DD, Baird AE, Tamimi F, Sohaei D, Conte HA, Prassas I, Diamandis EP. Tachykinins and the potential causal factors for post-COVID-19 condition. The Lancet. Microbe. PMID 37327802 DOI: 10.1016/S2666-5247(23)00111-8  0.569
2023 Crescioli S, Correa I, Ng J, Willsmore ZN, Laddach R, Chenoweth A, Chauhan J, Di Meo A, Stewart A, Kalliolia E, Alberts E, Adams R, Harris RJ, Mele S, Pellizzari G, ... ... Diamandis EP, et al. B cell profiles, antibody repertoire and reactivity reveal dysregulated responses with autoimmune features in melanoma. Nature Communications. 14: 3378. PMID 37291228 DOI: 10.1038/s41467-023-39042-y  0.598
2023 Lehto TK, Kovanen RM, Lintula S, Malén A, Stürenberg C, Erickson A, Pulkka OP, Stenman UH, Diamandis EP, Rannikko A, Mirtti T, Koistinen H. Prognostic impact of kallikrein-related peptidase transcript levels in prostate cancer. International Journal of Cancer. PMID 37139608 DOI: 10.1002/ijc.34551  0.321
2023 Ghorbani A, Avery LM, Sohaei D, Soosaipillai A, Richer M, Horbinski C, McCortney K, Xu W, Diamandis EP, Prassas I. Discovery of novel glioma serum biomarkers by proximity extension assay. Clinical Proteomics. 20: 12. PMID 36959545 DOI: 10.1186/s12014-023-09400-5  0.6
2023 Chatanaka MK, Sohaei D, Diamandis EP, Prassas I. Beyond the amyloid hypothesis: how current research implicates autoimmunity in Alzheimer's disease pathogenesis. Critical Reviews in Clinical Laboratory Sciences. 1-29. PMID 36941789 DOI: 10.1080/10408363.2023.2187342  0.59
2023 Ulndreaj A, Sohaei D, Thebault S, Pons-Belda OD, Fernandez-Uriarte A, Campbell C, Cheo D, Stengelin M, Sigal G, Freedman MS, Scarisbrick IA, Prassas I, Diamandis EP. Quantitation of neurofilament light chain protein in serum and cerebrospinal fluid from patients with multiple sclerosis using the MSD R-PLEX NfL assay. Diagnosis (Berlin, Germany). PMID 36788117 DOI: 10.1515/dx-2022-0125  0.588
2023 Khatab Z, Prassas I, Stengelin M, Diamandis EP. Prostate-Specific Antigen and Female Breast Cancer-Revisited. The Journal of Applied Laboratory Medicine. PMID 36760007 DOI: 10.1093/jalm/jfad002  0.633
2023 Pasic I, Ren AH, Nampoothiri RV, Prassas I, Lipton JH, Mattsson J, Diamandis EP, Michelis FV. Multiplex proteomics using proximity extension assay for the identification of protein biomarkers predictive of acute graft-vs.-host disease in allogeneic hematopoietic cell transplantation. Clinical Chemistry and Laboratory Medicine. PMID 36655501 DOI: 10.1515/cclm-2022-0916  0.601
2023 Koistinen H, Kovanen RM, Hollenberg MD, Dufour A, Radisky ES, Stenman UH, Batra J, Clements J, Hooper JD, Diamandis E, Schilling O, Rannikko A, Mirtti T. The roles of proteases in prostate cancer. Iubmb Life. PMID 36598826 DOI: 10.1002/iub.2700  0.307
2022 Ulndreaj A, Brinc D, Altan M, Pons-Belda OD, Fernandez-Uriarte A, Mu-Mosley H, Fattah F, von Itzstein MS, Soosaipillai A, Kulasingam V, Palaskas NL, Gerber DE, Diamandis EP, Heymach JV, Prassas I. Quantitation of cardiac troponin I in cancer patients treated with immune checkpoint inhibitors: a case-control study. Clinical Chemistry and Laboratory Medicine. PMID 36287134 DOI: 10.1515/cclm-2022-0471  0.622
2022 Sohaei D, Ulndreaj A, Mathew A, Campbell C, Stengelin M, Sigal G, Joe J, Romero D, Padmanabhan N, Ren A, Ghorbani A, Soosaipillai A, Kulasingam V, Prassas I, Diamandis EP. Sensitive Serology Measurements in the Saliva of Individuals with COVID-19 Symptoms Using a Multiplexed Immunoassay. The Journal of Applied Laboratory Medicine. PMID 36179121 DOI: 10.1093/jalm/jfac073  0.564
2022 Sohaei D, Hollenberg M, Janket SJ, Diamandis EP, Poda G, Prassas I. The therapeutic relevance of the Kallikrein-Kinin axis in SARS-cov-2-induced vascular pathology. Critical Reviews in Clinical Laboratory Sciences. 1-16. PMID 35930434 DOI: 10.1080/10408363.2022.2102578  0.594
2022 Ulndreaj A, Wang M, Misaghian S, Paone L, Sigal GB, Stengelin M, Campbell C, Van Nynatten LR, Soosaipillai A, Ghorbani A, Mathew A, Fraser DD, Diamandis EP, Prassas I. Patients with severe COVID-19 do not have elevated autoantibodies against common diagnostic autoantigens. Clinical Chemistry and Laboratory Medicine. PMID 35475723 DOI: 10.1515/cclm-2022-0239  0.601
2022 Ren A, Sohaei D, Ulndreaj A, Pons-Belda OD, Fernandez-Uriarte A, Zacharioudakis I, Sigal GB, Stengelin M, Mathew A, Campbell C, Padmanabhan N, Romero D, Joe J, Soosaipillai A, Kulasingam V, ... ... Diamandis EP, et al. Ultrasensitive assay for saliva-based SARS-CoV-2 antigen detection. Clinical Chemistry and Laboratory Medicine. PMID 35170269 DOI: 10.1515/cclm-2021-1142  0.572
2021 Miller MR, Robinson M, Fischer L, DiBattista A, Patel MA, Daley M, Bartha R, Dekaban GA, Menon RS, Shoemaker JK, Diamandis EP, Prassas I, Fraser DD. Putative Concussion Biomarkers Identified in Adolescent Male Athletes Using Targeted Plasma Proteomics. Frontiers in Neurology. 12: 787480. PMID 34987469 DOI: 10.3389/fneur.2021.787480  0.615
2021 Ren A, Prassas I, Sugumar V, Soosaipillai A, Bernardini M, Diamandis EP, Kulasingam V. Comparison of two multiplexed technologies for profiling >1,000 serum proteins that may associate with tumor burden. F1000research. 10: 509. PMID 34868557 DOI: 10.12688/f1000research.53364.1  0.639
2021 Lim B, Prassas I, Diamandis EP. From the amyloid hypothesis to the autoimmune hypothesis of Alzheimer's disease. Diagnosis (Berlin, Germany). PMID 34496166 DOI: 10.1515/dx-2021-0108  0.56
2021 Lim B, Grøntvedt GR, Bathala P, Kale SS, Campbell CT, Stengelin M, Sando SB, Prassas I, Diamandis EP, Bråthen G. CSF neurofilament light may predict progression from amnestic mild cognitive impairment to Alzheimer's disease dementia. Neurobiology of Aging. 107: 78-85. PMID 34403936 DOI: 10.1016/j.neurobiolaging.2021.07.013  0.573
2021 Aghel N, Gustafson D, Di Meo A, Music M, Prassas I, Seidman MA, Hansen AR, Thavendiranathan P, Diamandis EP, Delgado D, Fish JE. Recurrent Myocarditis Induced by Immune-Checkpoint Inhibitor Treatment Is Accompanied by Persistent Inflammatory Markers Despite Immunosuppressive Treatment. Jco Precision Oncology. 5. PMID 34337287 DOI: 10.1200/PO.20.00370  0.556
2021 Chen PJ, Pusica Y, Sohaei D, Prassas I, Diamandis EP. An overview of mental health during the COVID-19 pandemic. Diagnosis (Berlin, Germany). PMID 34214386 DOI: 10.1515/dx-2021-0046  0.535
2021 Fraser DD, Chen M, Ren A, Miller MR, Martin C, Daley M, Diamandis EP, Prassas I. Novel severe traumatic brain injury blood outcome biomarkers identified with proximity extension assay. Clinical Chemistry and Laboratory Medicine. PMID 34144643 DOI: 10.1515/cclm-2021-0103  0.587
2021 Pellizzari G, Martinez O, Crescioli S, Page R, Di Meo A, Mele S, Chiaruttini G, Hoinka J, Batruch I, Prassas I, Grandits M, López-Abente J, Bugallo-Blanco E, Ward M, Bax HJ, ... ... Diamandis EP, et al. Immunotherapy using IgE or CAR T cells for cancers expressing the tumor antigen SLC3A2. Journal For Immunotherapy of Cancer. 9. PMID 34112739 DOI: 10.1136/jitc-2020-002140  0.62
2021 Chen M, Ren AH, Prassas I, Soosaipillai A, Lim B, Fraser DD, Diamandis EP. Plasma Protein Profiling by Proximity Extension Assay Technology Reveals Novel Biomarkers of Traumatic Brain Injury-A Pilot Study. The Journal of Applied Laboratory Medicine. PMID 33778875 DOI: 10.1093/jalm/jfab004  0.605
2021 Prassas I, Fiala C, Diamandis EP. Assay requirements for COVID-19 testing: serology vs. rapid antigen tests. Clinical Chemistry and Laboratory Medicine. PMID 33730769 DOI: 10.1515/cclm-2021-0234  0.552
2020 Higgins V, Sohaei D, Diamandis EP, Prassas I. COVID-19: from3 an acute to chronic disease? Potential long-term health consequences. Critical Reviews in Clinical Laboratory Sciences. 1-23. PMID 33347790 DOI: 10.1080/10408363.2020.1860895  0.558
2020 Music M, Iafolla M, Soosaipillai A, Batruch I, Prassas I, Pintilie M, Hansen AR, Bedard PL, Lheureux S, Spreafico A, Razak AA, Siu LL, Diamandis EP. Predicting response and toxicity to PD-1 inhibition using serum autoantibodies identified from immuno-mass spectrometry. F1000research. 9: 337. PMID 33299547 DOI: 10.12688/f1000research.22715.1  0.592
2020 Ren AH, Prassas I, Soosaipillai A, Jarvi S, Gallinger S, Kulasingam V, Diamandis EP. Investigating a novel multiplex proteomics technology for detection of changes in serum protein concentrations that may correlate to tumor burden. F1000research. 9: 732. PMID 33274048 DOI: 10.12688/F1000Research.24654.1  0.676
2020 Lim B, Prassas I, Diamandis EP. Alzheimer Disease Pathogenesis: The Role of Autoimmunity. The Journal of Applied Laboratory Medicine. PMID 33241314 DOI: 10.1093/jalm/jfaa171  0.563
2020 Di Meo A, Sohaei D, Batruch I, Alexandrou P, Prassas I, Diamandis EP. Proteomic Profiling of the Human Tissue and Biological Fluid Proteome. Journal of Proteome Research. PMID 33107741 DOI: 10.1021/acs.jproteome.0c00502  0.612
2020 Ren AH, Soosaipillai A, Mathew A, Nikolenko G, Sardesai L, Stengelin M, Diamandis EP. Utility of a Fifth-Generation Ultrasensitive Prostate-Specific Antigen Assay for Monitoring Prostate Cancer Patients after Radical Prostatectomy with 3 Years of Follow-Up. Clinical Chemistry. 66: 1329-1338. PMID 33001184 DOI: 10.1093/Clinchem/Hvaa176  0.359
2020 Goldberg H, Glicksman R, Woon D, Hoffman A, Shaikh H, Chandrasekar T, Klaassen Z, Wallis CJD, Ahmad AE, Salgado N, Qu M, Moraes FY, Diamandis EP, Berlin A, Fleshner NE. Can postreatment free psa ratio be used to predict adverse outcomes in recurrent prostate cancer? Bju International. PMID 32926761 DOI: 10.1111/Bju.15236  0.36
2020 Fraser DD, Cepinskas G, Patterson EK, Slessarev M, Martin C, Daley M, Patel MA, Miller MR, O'Gorman DB, Gill SE, Pare G, Prassas I, Diamandis E. Novel Outcome Biomarkers Identified With Targeted Proteomic Analyses of Plasma From Critically Ill Coronavirus Disease 2019 Patients. Critical Care Explorations. 2: e0189. PMID 32904064 DOI: 10.1097/CCE.0000000000000189  0.611
2020 Fiala C, Diamandis EP. A multi-cancer detection test: focus on the positive predictive value. Annals of Oncology. 31: 1267-1268. PMID 32741675 DOI: 10.1016/J.Annonc.2020.05.028  0.31
2020 Di Paolo CT, Diamandis EP, Prassas I. The role of kallikreins in inflammatory skin disorders and their potential as therapeutic targets. Critical Reviews in Clinical Laboratory Sciences. 1-16. PMID 32568598 DOI: 10.1080/10408363.2020.1775171  0.608
2020 Diamandis P, Prassas I, Diamandis EP. Antibody tests for COVID-19: drawing attention to the importance of analytical specificity. Clinical Chemistry and Laboratory Medicine. PMID 32386187 DOI: 10.1515/Cclm-2020-0554  0.593
2020 Ren AH, Fiala CA, Diamandis EP, Kulasingam V. Pitfalls in cancer biomarker discovery and validation with emphasis on circulating tumor DNA. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. PMID 32277003 DOI: 10.1158/1055-9965.Epi-20-0074  0.375
2020 Fiala C, Diamandis EP. Circulating tumor DNA (ctDNA) is not a good proxy for liquid biopsies of tumor tissues for early detection. Clinical Chemistry and Laboratory Medicine. PMID 32160156 DOI: 10.1515/Cclm-2020-0083  0.345
2020 Filippou PS, Ren AH, Soosaipillai A, Safar R, Prassas I, Diamandis EP, Conner JR. Kallikrein-related peptidases protein expression in lymphoid tissues suggests potential implications in immune response. Clinical Biochemistry. PMID 31904348 DOI: 10.1016/J.Clinbiochem.2019.12.015  0.629
2020 Music M, Iafolla M, Soosaipillai A, Batruch I, Prassas I, Pintilie M, Hansen AR, Bedard PL, Lheureux S, Spreafico A, Razak AA, Siu LL, Diamandis EP. Predicting response and toxicity to PD-1 inhibition using serum autoantibodies identified from immuno-mass spectrometry F1000research. 9: 337. DOI: 10.12688/F1000Research.22715.1  0.626
2020 Music M, Iafolla M, Soosaipillai A, Batruch I, Prassas I, Siu LL, Diamandis EP. Abstract PR03: Immuno-mass spectrometric identification of serum biomarkers of response and toxicity to pembrolizumab Cancer Immunology Research. 8. DOI: 10.1158/2326-6074.Tumimm18-Pr03  0.68
2019 Lim B, Tsolaki M, Batruch I, Anastasiou A, Frontistis A, Prassas I, Diamandis EP. Putative autoantibodies in the cerebrospinal fluid of Alzheimer's disease patients. F1000research. 8: 1900. PMID 32089828 DOI: 10.12688/F1000Research.21140.1  0.648
2019 Dufresne J, Bowden P, Thavarajah T, Florentinus-Mefailoski A, Chen ZZ, Tucholska M, Norzin T, Ho MT, Phan M, Mohamed N, Ravandi A, Stanton E, Slutsky AS, Dos Santos CC, Romaschin A, ... ... Diamandis EP, et al. The plasma peptides of breast versus ovarian cancer. Clinical Proteomics. 16: 43. PMID 31889940 DOI: 10.1186/S12014-019-9262-0  0.338
2019 Di Meo A, Batruch I, Brown MD, Yang C, Finelli A, Jewett MAS, Diamandis EP, Yousef GM. Identification of Prognostic Biomarkers in the Urinary Peptidome of the Small Renal Mass. The American Journal of Pathology. 189: 2366-2376. PMID 31761032 DOI: 10.1016/J.Ajpath.2019.08.015  0.528
2019 Di Meo A, Brown MD, Finelli A, Jewett MAS, Diamandis EP, Yousef GM. Prognostic Urinary miRNAs for the Assessment of Small Renal Masses. Clinical Biochemistry. PMID 31672647 DOI: 10.1016/J.Clinbiochem.2019.10.002  0.494
2019 Di Meo A, Batruch I, Brown MD, Yang C, Finelli A, Jewett MA, Diamandis EP, Yousef GM. Searching for Prognostic Biomarkers for Small Renal Masses in the Urinary Proteome. International Journal of Cancer. PMID 31465112 DOI: 10.1002/Ijc.32650  0.545
2019 Lim B, Tsolaki M, Soosaipillai A, Brown M, Zilakaki M, Tagaraki F, Fotiou D, Koutsouraki E, Grosi E, Prassas I, Diamandis EP. Liquid biopsy of cerebrospinal fluid identifies neuronal pentraxin receptor (NPTXR) as a biomarker of progression of Alzheimer's disease. Clinical Chemistry and Laboratory Medicine. PMID 31415236 DOI: 10.1515/Cclm-2019-0428  0.58
2019 Music M, Iafolla MAJ, Ren AH, Soosaipillai A, Prassas I, Diamandis EP. Serum PD-1 is elevated after pembrolizumab treatment but has no predictive value. Molecular Cancer Therapeutics. PMID 31363009 DOI: 10.1158/1535-7163.Mct-19-0132  0.613
2019 Music M, Soosaipillai A, Batruch I, Prassas I, Bogdanos DP, Diamandis EP. Correction to: A proteome-wide immuno-mass spectrometric identification of serum autoantibodies. Clinical Proteomics. 16: 30. PMID 31346327 DOI: 10.1186/S12014-019-9250-4  0.574
2019 Music M, Soosaipillai A, Batruch I, Prassas I, Bogdanos DP, Diamandis EP. A proteome-wide immuno-mass spectrometric identification of serum autoantibodies. Clinical Proteomics. 16: 25. PMID 31249498 DOI: 10.1186/s12014-019-9246-0  0.629
2019 Drabovich AP, Saraon P, Drabovich M, Karakosta T, Dimitromanolakis A, Hyndman ME, Jarvi K, Diamandis EP. Multi-omics biomarker pipeline reveals elevated levels of protein-glutamine gamma-glutamyltransferase 4 in seminal plasma of prostate cancer patients. Molecular & Cellular Proteomics : McP. PMID 31249104 DOI: 10.1074/Mcp.Ra119.001612  0.745
2019 Di Paolo CT, Filippou PS, Yu Y, Poda G, Diamandis EP, Prassas I. Screening of chemical libraries in pursuit of kallikrein-5 specific inhibitors for the treatment of inflammatory dermatoses. Clinical Chemistry and Laboratory Medicine. PMID 31129650 DOI: 10.1515/Cclm-2019-0123  0.619
2019 Pampalakis G, Zingkou E, Sidiropoulos KG, Diamandis EP, Zoumpourlis V, Yousef GM, Sotiropoulou G. Biochemical pathways mediated by KLK6 protease in breast cancer. Molecular Oncology. PMID 30980596 DOI: 10.1002/1878-0261.12493  0.58
2019 Vasiliou SK, Diamandis EP. Androgen receptor: A promising therapeutic target in breast cancer. Critical Reviews in Clinical Laboratory Sciences. 1-24. PMID 30821186 DOI: 10.1080/10408363.2019.1575643  0.35
2019 Dimitrakopoulos L, Prassas I, Sieuwerts AM, Diamandis EP, Martens JWM, Charames GS. Proteome-wide onco-proteogenomic somatic variant identification in ER-positive breast cancer. Clinical Biochemistry. PMID 30684468 DOI: 10.1016/J.Clinbiochem.2019.01.005  0.652
2019 Schiza C, Korbakis D, Jarvi K, Diamandis EP, Drabovich AP. Identification of TEX101-associated Proteins Through Proteomic Measurement of Human Spermatozoa Homozygous for the Missense Variant rs35033974. Molecular & Cellular Proteomics : McP. 18: 338-351. PMID 30429210 DOI: 10.1074/Mcp.Ra118.001170  0.304
2019 Bjartell A, Paju A, Stenman UH, Väisänen V, Aumüller G, Diamandis E, Becker C, Lilja H. Studies on phenotypic expression patterns of proteases and protease inhibitors in benign compared to malignant prostate tissues. Prostate Cancer and Prostatic Diseases. 3: S7. PMID 12497117 DOI: 10.1038/Sj.Pcan.4500431  0.335
2018 Dufresne J, Bowden P, Thavarajah T, Florentinus-Mefailoski A, Chen ZZ, Tucholska M, Norzin T, Ho MT, Phan M, Mohamed N, Ravandi A, Stanton E, Slutsky AS, Dos Santos CC, Romaschin A, ... ... Diamandis EP, et al. The plasma peptides of ovarian cancer. Clinical Proteomics. 15: 41. PMID 30598658 DOI: 10.1186/S12014-018-9215-Z  0.33
2018 Fiala C, Diamandis EP. Can Grail find the trail to early cancer detection? Clinical Chemistry and Laboratory Medicine. PMID 30530899 DOI: 10.1515/Cclm-2018-1249  0.341
2018 Fiala C, Diamandis EP. Utility of circulating tumor DNA in cancer diagnostics with emphasis on early detection. Bmc Medicine. 16: 166. PMID 30285732 DOI: 10.1186/S12916-018-1157-9  0.376
2018 Music M, Prassas I, Diamandis EP. Optimizing cancer immunotherapy: Is it time for personalized predictive biomarkers? Critical Reviews in Clinical Laboratory Sciences. 1-14. PMID 30277835 DOI: 10.1080/10408363.2018.1499706  0.675
2018 Diamandis EP, Scorilas A, Prassas I, Plebani M. The International Society for Enzymology: a glorious history, a golden legacy. Clinical Chemistry and Laboratory Medicine. PMID 30157030 DOI: 10.1515/Cclm-2018-0766  0.563
2018 Schiza C, Korbakis D, Panteleli E, Jarvi K, Drabovich AP, Diamandis EP. Discovery of a human testis-specific protein complex TEX101-DPEP3 and selection of its disrupting antibodies. Molecular & Cellular Proteomics : McP. PMID 30097533 DOI: 10.1074/Mcp.Ra118.000749  0.305
2018 Filippou PS, Ren AH, Soosaipillai A, Papaioannou MD, Korbakis D, Safar R, Diamandis EP, Conner J. Expression profile of human tissue kallikrein 15 provides preliminary insights into its roles in the prostate and testis. Clinical Biochemistry. PMID 29958881 DOI: 10.1016/J.Clinbiochem.2018.06.017  0.393
2018 Filippou PS, Ren AH, Bala S, Papaioannou MD, Brinc D, Prassas I, Karakosta T, Diamandis EP. Biochemical characterization of human tissue kallikrein 15 and examination of its potential role in cancer. Clinical Biochemistry. PMID 29928903 DOI: 10.1016/J.Clinbiochem.2018.06.007  0.682
2018 Leung F, Bernardini MQ, Liang K, Batruch I, Rouzbahman M, Diamandis EP, Kulasingam V. Unraveling endometriosis-associated ovarian carcinomas using integrative proteomics. F1000research. 7: 189. PMID 29721309 DOI: 10.12688/F1000Research.13863.2  0.357
2018 Begcevic I, Brinc D, Dukic L, Simundic AM, Zavoreo I, Basic Kes V, Martínez-Morillo E, Batruch I, Drabovich AP, Diamandis EP. Targeted mass spectrometry-based assays for relative quantification of thirty brain-related proteins and their clinical applications. Journal of Proteome Research. PMID 29708756 DOI: 10.1021/Acs.Jproteome.7B00768  0.304
2018 Di Meo A, Wang C, Cheng Y, Diamandis EP, Yousef GM. The miRNA-kallikrein interaction: a mosaic of epigenetic regulation in cancer. Biological Chemistry. PMID 29604203 DOI: 10.1515/Hsz-2018-0112  0.533
2018 Reuning U, Magdolen V, Courty Y, Clements JA, Yousef GM, Scorilas A, Talieri M, Diamandis EP. Manfred Schmitt (1947-2018). Biological Chemistry. PMID 29601294 DOI: 10.1515/Hsz-2018-0184  0.434
2018 Meo AD, Saleeb R, Wala SJ, Khella HW, Ding Q, Zhai H, Krishan K, Krizova A, Gabril M, Evans A, Brimo F, Pasic MD, Finelli A, Diamandis EP, Yousef GM. A miRNA-based classification of renal cell carcinoma subtypes by PCR and in situ hybridization. Oncotarget. 9: 2092-2104. PMID 29416756 DOI: 10.18632/Oncotarget.23162  0.47
2017 Filippou P, Diamandis EP. Half-Century of Cancer Biomarkers: Lessons from the Past and Projections for the Future. The Journal of Applied Laboratory Medicine. 2: 288-290. PMID 32630979 DOI: 10.1373/Jalm.2016.021824  0.376
2017 Kulasingam V, Prassas I, Diamandis EP. Towards personalized tumor markers. Npj Precision Oncology. 1: 17. PMID 29872704 DOI: 10.1038/s41698-017-0021-2  0.67
2017 Ravipaty S, Wu W, Dalvi A, Tanna N, Andreazi J, Friss T, Klotz A, Liao C, Garren J, Schofield S, Diamandis EP, Klein EA, Dobi A, Srivastava S, Tekumalla P, et al. Clinical Validation of a Serum Protein Panel (FLNA, FLNB and KRT19) for Diagnosis of Prostate Cancer. Journal of Molecular Biomarkers & Diagnosis. 8. PMID 29682400 DOI: 10.4172/2155-9929.1000323  0.399
2017 Diamandis EP, Fiala C. Can circulating tumor DNA be used for direct and early stage cancer detection? F1000research. 6: 2129. PMID 29333251 DOI: 10.12688/F1000Research.13440.1  0.337
2017 Dimitrakopoulos L, Prassas I, Diamandis EP, Charames GS. Onco-proteogenomics: Multi-omics level data integration for accurate phenotype prediction. Critical Reviews in Clinical Laboratory Sciences. 1-19. PMID 29025326 DOI: 10.1080/10408363.2017.1384446  0.654
2017 Muytjens CMJ, Yu Y, Diamandis EP. Discovery of Antimicrobial Peptides in Cervical-vaginal Fluid from Healthy Non-pregnant Women Via an Integrated Proteome and Peptidome Analysis. Proteomics. PMID 28941238 DOI: 10.1002/Pmic.201600461  0.314
2017 Eklund E, Diamandis EP, Muytjens C, Wheeler S, Mathew A, Stengelin M, Glezer E, Nikolenko G, Brown MD, Zheng Y, Hirschberg AL. Serum complexed and free prostate specific antigen levels are lower in female elite athletes in comparison to control women. F1000research. 6: 1131. PMID 28815018 DOI: 10.12688/F1000Research.11821.1  0.329
2017 Fiala C, Diamandis EP. Circulating tumor DNA for personalized lung cancer monitoring. Bmc Medicine. 15: 157. PMID 28814291 DOI: 10.1186/S12916-017-0921-6  0.313
2017 Farkona S, Soosaipillai A, Filippou P, Korbakis D, Serra S, Rückert F, Diamandis EP, Blasutig IM. Generation of monoclonal antibodies and development of an immunofluorometric assay for the detection of CUZD1 in tissues and biological fluids. Clinical Biochemistry. PMID 28746862 DOI: 10.1016/J.Clinbiochem.2017.07.012  0.328
2017 Forse CL, Rahimi M, Diamandis EP, Assarzadegan N, Dawson H, Grin A, Kennedy E, O'Connor B, Messenger DE, Riddell RH, Kirsch R, Karagiannis GS. HtrA3 stromal expression is correlated with tumor budding in stage II colorectal cancer. Experimental and Molecular Pathology. PMID 28716573 DOI: 10.1016/J.Yexmp.2017.07.002  0.546
2017 Korbakis D, Soosaipillai A, Diamandis EP. Study of kallikrein-related peptidase 6 (KLK6) and its complex with α1-antitrypsin in biological fluids. Clinical Chemistry and Laboratory Medicine. PMID 28672746 DOI: 10.1515/Cclm-2017-0017  0.399
2017 Delaunay T, Deschamps L, Haddada M, Walker F, Soosaipillai A, Soualmia F, El Amri C, Diamandis EP, Brattsand M, Magdolen V, Darmoul D. Aberrant expression of kallikrein-related peptidase 7 is correlated to human melanoma aggressiveness by stimulating cell migration and invasion. Molecular Oncology. PMID 28636767 DOI: 10.1002/1878-0261.12103  0.382
2017 Cretu D, Gao L, Liang K, Soosaipillai A, Diamandis EP, Chandran V. Novel serum biomarkers differentiate psoriatic arthritis from psoriasis without psoriatic arthritis. Arthritis Care & Research. PMID 28586166 DOI: 10.1002/Acr.23298  0.317
2017 Filippou PS, Farkona S, Brinc D, Yu Y, Prassas I, Diamandis EP. Biochemical and Functional Characterization of the Human Tissue Kallikrein 9. The Biochemical Journal. PMID 28559305 DOI: 10.1042/Bcj20170174  0.64
2017 Nasser NJ, Thoms J, Soosaipillai A, Pintilie M, Wang R, Diamandis EP, Bristow RG. Human tissue Kallikreins: Blood levels and response to radiotherapy in intermediate risk prostate cancer. Radiotherapy and Oncology : Journal of the European Society For Therapeutic Radiology and Oncology. PMID 28427756 DOI: 10.1016/J.Radonc.2017.03.023  0.398
2017 Briollais L, Ozcelik H, Xu J, Kwiatkowski M, Lalonde E, Sendorek DH, Fleshner NE, Recker F, Kuk C, Olkhov-Mitsel E, Juvet T, Prassas I, Trachtenberg J, Toi A, Fraser M, ... ... Diamandis EP, et al. Germline Mutations in the Kallikrein 6 Region and Predisposition for Aggressive Prostate Cancer. Journal of the National Cancer Institute. 109. PMID 28376164 DOI: 10.1093/Jnci/Djw258  0.677
2017 Diamandis EP, Stanczyk FZ, Wheeler S, Mathew A, Stengelin M, Nikolenko G, Glezer EN, Brown MD, Zheng Y, Chen YH, Wu HL, Azziz R. Serum complexed and free prostate-specific antigen (PSA) for the diagnosis of the polycystic ovarian syndrome (PCOS). Clinical Chemistry and Laboratory Medicine. PMID 28361781 DOI: 10.1515/Cclm-2016-1124  0.339
2017 Korbakis D, Schiza C, Brinc D, Soosaipillai A, Karakosta TD, Légaré C, Sullivan R, Mullen B, Jarvi K, Diamandis EP, Drabovich AP. Preclinical evaluation of a TEX101 protein ELISA test for the differential diagnosis of male infertility. Bmc Medicine. 15: 60. PMID 28330469 DOI: 10.1186/S12916-017-0817-5  0.311
2017 Dimitrakopoulos L, Prassas I, Berns EM, Foekens JA, Diamandis EP, Charames GS. Variant peptide detection utilizing mass spectrometry: laying the foundations for proteogenomic identification and validation. Clinical Chemistry and Laboratory Medicine. PMID 28157690 DOI: 10.1515/Cclm-2016-0947  0.609
2017 Filippou P, Korbakis D, Farkona S, Soosaipillai A, Karakosta T, Diamandis EP. A new enzyme-linked immunosorbent assay (ELISA) for human free and bound kallikrein 9. Clinical Proteomics. 14: 4. PMID 28115917 DOI: 10.1186/S12014-017-9140-6  0.309
2017 Yu Y, Prassas I, Muytjens CM, Diamandis EP. Proteomic and peptidomic analysis of human sweat with emphasis on proteolysis. Journal of Proteomics. PMID 28095327 DOI: 10.1016/J.Jprot.2017.01.005  0.638
2017 Ravipaty S, Wu W, Dalvi A, Tanna N, Andreazi J, Friss T, Klotz A, Liao C, Garren J, Schofield S, Diamandis EP, Klein EA, Dobi A, Srivastava S, Tekumalla P, et al. Abstract 3826: Clinical validation of a serum protein panel (FLNA, FLNB and KRT19) for diagnosis and prognosis of prostate cancer Cancer Research. 77: 3826-3826. DOI: 10.1158/1538-7445.Am2017-3826  0.405
2017 Briollais L, Ozcelik H, Xu J, Kwiatkowski M, Lalonde E, Sendorek DH, Fleshner NE, Recker F, Kuk C, Olkhov-Mitsel E, Savas S, Hanna S, Juvet T, Hunter GA, Friedlander M, ... ... Diamandis EP, et al. PD65-01 GERMLINE MUTATIONS IN THE KALLIKREIN 6 REGION AND PREDISPOSITION FOR AGGRESSIVE PROSTATE CANCER Journal of Urology. 197. DOI: 10.1016/J.Juro.2017.02.2951  0.647
2016 Kulasingam V, Diamandis EP. Genomic profiling for copy number changes in plasma of ovarian cancer patients - a new era for cancer diagnostics? Bmc Medicine. 14: 186. PMID 27852253 DOI: 10.1186/S12916-016-0741-0  0.363
2016 White-Al Habeeb N, Kulasingam V, Diamandis EP, Yousef GM, Tsongalis GJ, Vermeulen L, Zhu Z, Kamel-Reid S. The Use of Targeted Therapies for Precision Medicine in Oncology. Clinical Chemistry. PMID 27679436 DOI: 10.1373/Clinchem.2015.247882  0.545
2016 Muytjens CM, Vasiliou SK, Oikonomopoulou K, Prassas I, Diamandis EP. Putative functions of tissue kallikrein-related peptidases in vaginal fluid. Nature Reviews. Urology. PMID 27603220 DOI: 10.1038/Nrurol.2016.161  0.629
2016 Ahmed N, Dorn J, Napieralski R, Drecoll E, Kotzsch M, Goettig P, Zein E, Avril S, Kiechle M, Diamandis EP, Schmitt M, Magdolen V. Clinical relevance of kallikrein-related peptidase 6 (KLK6) and 8 (KLK8) mRNA expression in advanced serous ovarian cancer. Biological Chemistry. PMID 27483364 DOI: 10.1515/Hsz-2016-0177  0.366
2016 Dragani TA, Castells A, Kulasingam V, Diamandis EP, Earl H, Iams WT, Lovly CM, Sedelaar JP, Schalken JA. Major milestones in translational oncology. Bmc Medicine. 14: 110. PMID 27469586 DOI: 10.1186/S12916-016-0654-Y  0.399
2016 Leung F, Bernardini MQ, Brown MD, Zheng Y, Molina R, Bast RC, Davis G, Serra S, Diamandis EP, Kulasingam V. Validation of a novel biomarker panel for the detection of ovarian cancer. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. PMID 27448593 DOI: 10.1158/1055-9965.Epi-15-1299  0.387
2016 Di Meo A, Batruch I, Yousef AG, Pasic MD, Diamandis EP, Yousef GM. An integrated proteomic and peptidomic assessment of the normal human urinome. Clinical Chemistry and Laboratory Medicine. PMID 27394047 DOI: 10.1515/Cclm-2016-0390  0.542
2016 Karakosta TD, Soosaipillai A, Diamandis EP, Batruch I, Drabovich AP. Quantification of Human Kallikrein-Related Peptidases in Biological Fluids by Multi-Platform Targeted Mass Spectrometry Assays. Molecular & Cellular Proteomics : McP. PMID 27371727 DOI: 10.1074/Mcp.M115.057695  0.399
2016 Leung F, Kulasingam V, Diamandis EP, Hoon DS, Kinzler K, Pantel K, Alix-Panabières C. Circulating Tumor DNA as a Cancer Biomarker: Fact or Fiction? Clinical Chemistry. PMID 27259816 DOI: 10.1373/Clinchem.2016.260331  0.34
2016 Musrap N, Diamandis EP. Prostate-Specific Antigen as a Marker of Hyperandrogenism in Women and Its Implications for Antidoping. Clinical Chemistry. PMID 27259815 DOI: 10.1373/Clinchem.2016.256198  0.347
2016 Mangé A, Dimitrakopoulos L, Soosaipillai A, Coopman P, Diamandis EP, Solassol J. An integrated cell line-based discovery strategy identified follistatin and kallikrein 6 as serum biomarker candidates of breast carcinoma. Journal of Proteomics. PMID 27168011 DOI: 10.1016/J.Jprot.2016.04.050  0.406
2016 Farkona S, Diamandis EP, Blasutig IM. Cancer immunotherapy: the beginning of the end of cancer? Bmc Medicine. 14: 73. PMID 27151159 DOI: 10.1186/S12916-016-0623-5  0.351
2016 Dorn J, Yassouridis A, Walch A, Diamandis EP, Schmitt M, Kiechle M, Wang P, Drecoll E, Schmalfeldt B, Loessner D, Kotzsch M, Magdolen V. Assessment of kallikrein-related peptidase 5 (KLK5) protein expression in tumor tissue of advanced ovarian cancer patients by immunohistochemistry and ELISA: correlation with clinical outcome. American Journal of Cancer Research. 6: 61-70. PMID 27073723  0.312
2016 Drabovich AP, Pavlou MP, Schiza C, Diamandis EP. Dynamics of protein expression reveals primary targets and secondary messengers of estrogen receptor alpha signaling in MCF-7 breast cancer cells. Molecular & Cellular Proteomics : McP. PMID 27067054 DOI: 10.1074/Mcp.M115.057257  0.342
2016 Diamandis EP. Significant increase of serum prostate-specific antigen after exercise. Clinical Chemistry and Laboratory Medicine. PMID 26910748 DOI: 10.1515/Cclm-2016-0018  0.302
2016 Filippou PS, Karagiannis GS, Musrap N, Diamandis EP. Kallikrein-related peptidases (KLKs) and the hallmarks of cancer. Critical Reviews in Clinical Laboratory Sciences. 1-58. PMID 26886390 DOI: 10.3109/10408363.2016.1154643  0.623
2016 Dimitrakopoulos L, Prassas I, Diamandis EP, Nesvizhskii A, Kislinger T, Jaffe J, Drabovich A. Proteogenomics: Opportunities and Caveats. Clinical Chemistry. 62: 551-7. PMID 26817480 DOI: 10.1373/Clinchem.2015.247858  0.633
2016 Diamandis EP. Cancer dynamics and the success of cancer screening programs. Clinical Chemistry and Laboratory Medicine. PMID 26751900 DOI: 10.1515/Cclm-2015-1201  0.32
2016 Diamandis EP, Li M. The side effects of translational omics: overtesting, overdiagnosis, overtreatment. Clinical Chemistry and Laboratory Medicine. 54: 389-96. PMID 26444364 DOI: 10.1515/Cclm-2015-0762  0.319
2016 Diamandis EP, Plebani M. Glypican-1 as a highly sensitive and specific pancreatic cancer biomarker. Clinical Chemistry and Laboratory Medicine. 54: e1-2. PMID 26389634 DOI: 10.1515/Cclm-2015-0773  0.364
2016 Leung F, Bernardini MQ, Clarke B, Rouzbahman M, Diamandis EP, Kulasingam V. Abstract B13: Discovery of novel subtype-specific ovarian cancer biomarkers via integrated tissue proteomics. Clinical Cancer Research. 22. DOI: 10.1158/1557-3265.Ovca15-B13  0.42
2016 Chandran V, Cretu D, Gao L, Liang K, Diamandis E. AB0748 Novel Biomarkers Distinguish Psoriatic Arthritis from Psoriasis Annals of the Rheumatic Diseases. 75: 1160.3-1161. DOI: 10.1136/Annrheumdis-2016-Eular.3697  0.329
2015 Drucker KL, Gianinni C, Decker PA, Diamandis EP, Scarisbrick IA. Prognostic significance of multiple kallikreins in high-grade astrocytoma. Bmc Cancer. 15: 565. PMID 26231762 DOI: 10.1186/S12885-015-1566-5  0.392
2015 Korbakis D, Dimitromanolakis A, Prassas I, Davis GJ, Barber E, Reckamp KL, Blasutig I, Diamandis EP. Serum LAMC2 enhances the prognostic value of a multi-parametric panel in non-small cell lung cancer. British Journal of Cancer. 113: 484-91. PMID 26180921 DOI: 10.1038/Bjc.2015.171  0.666
2015 Yu Y, Prassas I, Dimitromanolakis A, Diamandis EP. Novel Biological Substrates of Human Kallikrein 7 Identified through Degradomics. The Journal of Biological Chemistry. 290: 17762-75. PMID 26032414 DOI: 10.1074/Jbc.M115.643551  0.644
2015 Musrap N, Tuccitto A, Karagiannis GS, Saraon P, Batruch I, Diamandis EP. Comparative Proteomics of Ovarian Cancer Aggregate Formation Reveals an Increased Expression of Calcium-activated Chloride Channel Regulator 1 (CLCA1). The Journal of Biological Chemistry. 290: 17218-27. PMID 26004777 DOI: 10.1074/Jbc.M115.639773  0.788
2015 Duffy MJ, Sturgeon CM, Sölétormos G, Barak V, Molina R, Hayes DF, Diamandis EP, Bossuyt PM. Validation of New Cancer Biomarkers: A Position Statement from the European Group on Tumor Markers. Clinical Chemistry. 61: 809-820. PMID 25882892 DOI: 10.1373/Clinchem.2015.239863  0.388
2015 Korbakis D, Brinc D, Schiza C, Soosaipillai A, Jarvi K, Drabovich AP, Diamandis EP. Immunocapture-Selected Reaction Monitoring Screening Facilitates the Development of ELISA for the Measurement of Native TEX101 in Biological Fluids. Molecular & Cellular Proteomics : McP. 14: 1517-26. PMID 25813379 DOI: 10.1074/Mcp.M114.047571  0.31
2015 Prassas I, Eissa A, Poda G, Diamandis EP. Unleashing the therapeutic potential of human kallikrein-related serine proteases. Nature Reviews. Drug Discovery. 14: 183-202. PMID 25698643 DOI: 10.1038/Nrd4534  0.733
2015 Schully SD, Carrick DM, Mechanic LE, Srivastava S, Anderson GL, Baron JA, Berg CD, Cullen J, Diamandis EP, Doria-Rose VP, Goddard KA, Hankinson SE, Kushi LH, Larson EB, McShane LM, et al. Leveraging biospecimen resources for discovery or validation of markers for early cancer detection. Journal of the National Cancer Institute. 107. PMID 25688116 DOI: 10.1093/Jnci/Djv012  0.367
2015 Cretu D, Liang K, Saraon P, Batruch I, Diamandis EP, Chandran V. Quantitative tandem mass-spectrometry of skin tissue reveals putative psoriatic arthritis biomarkers. Clinical Proteomics. 12: 1. PMID 25678896 DOI: 10.1186/1559-0275-12-1  0.726
2015 Diamandis EP. The Hundred Person Wellness Project and Google's Baseline Study: medical revolution or unnecessary and potentially harmful over-testing? Bmc Medicine. 13: 5. PMID 25575898 DOI: 10.1186/S12916-014-0239-6  0.301
2015 Rotondo F, Di Ieva A, Kovacs K, Cusimano MD, Syro LV, Diamandis EP, Yousef GM. Human kallikrein 10 in surgically removed human pituitary adenomas. Hormones (Athens, Greece). 14: 272-9. PMID 25553760 DOI: 10.14310/Horm.2002.1558  0.506
2015 Di Meo A, Rotondo F, Kovacs K, Cusimano MD, Syro LV, Di Ieva A, Diamandis EP, Yousef GM. Human Kallikrein 10 Expression in Surgically Removed Human Pituitary Corticotroph Adenomas: An Immunohistochemical Study. Applied Immunohistochemistry & Molecular Morphology : Aimm / Official Publication of the Society For Applied Immunohistochemistry. 23: 433-7. PMID 25517869 DOI: 10.1097/Pai.0000000000000108  0.46
2015 Korbakis D, Prassas I, Brinc D, Batruch I, Krastins B, Lopez MF, Diamandis EP. Delineating monoclonal antibody specificity by mass spectrometry. Journal of Proteomics. 114: 115-24. PMID 25462431 DOI: 10.1016/J.Jprot.2014.11.004  0.62
2015 Dorn J, Bronger H, Kates R, Slotta-Huspenina J, Schmalfeldt B, Kiechle M, Diamandis EP, Soosaipillai A, Schmitt M, Harbeck N. OVSCORE - a validated score to identify ovarian cancer patients not suitable for primary surgery. Oncology Letters. 9: 418-424. PMID 25436002 DOI: 10.3892/Ol.2014.2630  0.365
2015 Drabovich AP, Martínez-Morillo E, Diamandis EP. Toward an integrated pipeline for protein biomarker development. Biochimica Et Biophysica Acta. 1854: 677-86. PMID 25218201 DOI: 10.1016/J.Bbapap.2014.09.006  0.309
2015 Karagiannis GS, Musrap N, Saraon P, Treacy A, Schaeffer DF, Kirsch R, Riddell RH, Diamandis EP. Bone morphogenetic protein antagonist gremlin-1 regulates colon cancer progression. Biological Chemistry. 396: 163-83. PMID 25153376 DOI: 10.1515/Hsz-2014-0221  0.778
2015 Narain NR, Diers A, Ouro-Djobo R, Chan J, Rodrigues LO, Vishnudas VK, Diamandis EP, Akmaev VR, Sarangarajan R. Abstract 538: Identification and validation of novel prostate cancer biomarkers using the Berg Interrogative Biology™ platform Cancer Research. 75: 538-538. DOI: 10.1158/1538-7445.Am2015-538  0.421
2015 Skates SJ, Anderson KS, Liu T, Kulasingam V, Rabideau D, Wu C, Gillette M, Godwin AK, Urban N, Lokshin A, Marks J, Diamandis E, Zhang Z, Srivastava S, Kagan J, et al. Abstract 1570: Early Detection Research Network (EDRN) validation of circulating ovarian cancer biomarkers Cancer Research. 75: 1570-1570. DOI: 10.1158/1538-7445.Am2015-1570  0.328
2015 Korbakis D, Dimitromanolakis A, Prassas I, Davis GJ, Barber E, Reckamp KL, Blasutig I, Diamandis EP. Serum LAMC2 enhances the prognostic value of a multi-parametric panel in non-small cell lung cancer British Journal of Cancer. 113: 484-491. DOI: 10.1038/bjc.2015.171  0.62
2015 Musrap N, Tuccitto A, Karagiannis G, Saraon P, Diamandis E. Comparative proteomics of ovarian cancer spheroid formation reveals an increased expression of calcium-activated chloride channel regulator 1 Gynecologic Oncology. 137: 116. DOI: 10.1016/J.Ygyno.2015.01.288  0.758
2015 Briollais L, Ozcelik H, Kwiatkowski M, Xu J, Savas S, Olkhov-Mitsel E, Recker F, Kuk C, Hanna S, Fleshner NE, Juvet T, Friedlander M, Li H, Chadwick K, Trachtenberg J, ... ... Diamandis EP, et al. Mp61-01 Functional Role Of The Kallikrein 6 Region Of The Kallikrein Locus In Genetic Predisposition For Aggressive (Gleason ≥8) Prostate Cancer: Fine-Mapping And Methylation Study In A Canadian Cohort And The Swiss Arm Of The European Randomized Study For Prostate Cancer Screening The Journal of Urology. 193. DOI: 10.1016/J.Juro.2015.02.2182  0.358
2014 Saraon P, Drabovich AP, Jarvi KA, Diamandis EP. Mechanisms of Androgen-Independent Prostate Cancer. Ejifcc. 25: 42-54. PMID 27683456  0.735
2014 Leung F, Diamandis EP, Kulasingam V. Ovarian cancer biomarkers: current state and future implications from high-throughput technologies. Advances in Clinical Chemistry. 66: 25-77. PMID 25344985 DOI: 10.1016/B978-0-12-801401-1.00002-5  0.387
2014 Satkunasivam R, Zhang W, Trachtenberg J, Toi A, Yu C, Diamandis E, Kattan MW, Narod SA, Nam RK. Human kallikrein-2 gene and protein expression predicts prostate cancer at repeat biopsy. Springerplus. 3: 295. PMID 25279276 DOI: 10.1186/2193-1801-3-295  0.376
2014 Chan A, Prassas I, Dimitromanolakis A, Brand RE, Serra S, Diamandis EP, Blasutig IM. Validation of biomarkers that complement CA19.9 in detecting early pancreatic cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 20: 5787-95. PMID 25239611 DOI: 10.1158/1078-0432.Ccr-14-0289  0.677
2014 Diamandis EP. Towards identification of true cancer biomarkers. Bmc Medicine. 12: 156. PMID 25220599 DOI: 10.1186/S12916-014-0156-8  0.364
2014 Walker F, Nicole P, Jallane A, Soosaipillai A, Mosbach V, Oikonomopoulou K, Diamandis EP, Magdolen V, Darmoul D. Kallikrein-related peptidase 7 (KLK7) is a proliferative factor that is aberrantly expressed in human colon cancer. Biological Chemistry. 395: 1075-86. PMID 25153388 DOI: 10.1515/Hsz-2014-0142  0.399
2014 Sukumar N, Scott E, Dimitromanolakis A, Misiak A, Prassas I, Diamandis EP, Konvalinka A. Mining for single nucleotide variants (SNVs) at the kallikrein locus with predicted functional consequences. Biological Chemistry. 395: 1037-50. PMID 25153386 DOI: 10.1515/Hsz-2014-0136  0.618
2014 Yousef GM, Pasic M, Diamandis EP. Highlight: the 5th International Symposium on Kallikreins and Kallikrein-Related Peptidases. Biological Chemistry. 395: 913-4. PMID 25153379 DOI: 10.1515/Hsz-2014-0228  0.453
2014 Cretu D, Prassas I, Saraon P, Batruch I, Gandhi R, Diamandis EP, Chandran V. Identification of psoriatic arthritis mediators in synovial fluid by quantitative mass spectrometry. Clinical Proteomics. 11: 27. PMID 25097465 DOI: 10.1186/1559-0275-11-27  0.795
2014 Smith CR, Batruch I, Bauça JM, Kosanam H, Ridley J, Bernardini MQ, Leung F, Diamandis EP, Kulasingam V. Deciphering the peptidome of urine from ovarian cancer patients and healthy controls. Clinical Proteomics. 11: 23. PMID 24982608 DOI: 10.1186/1559-0275-11-23  0.381
2014 Sokratous K, Hadjisavvas A, Diamandis EP, Kyriacou K. The role of ubiquitin-binding domains in human pathophysiology. Critical Reviews in Clinical Laboratory Sciences. 51: 280-90. PMID 24901807 DOI: 10.3109/10408363.2014.915287  0.302
2014 Yu Y, Prassas I, Diamandis EP. Putative kallikrein substrates and their (patho)biological functions. Biological Chemistry. 395: 931-43. PMID 24854536 DOI: 10.1515/Hsz-2014-0129  0.625
2014 Di Meo A, Diamandis EP, Rodriguez H, Hoofnagle AN, Ioannidis J, Lopez M. What is wrong with clinical proteomics? Clinical Chemistry. 60: 1258-66. PMID 24831563 DOI: 10.1373/Clinchem.2014.225185  0.314
2014 Karagiannis GS, Treacy A, Messenger D, Grin A, Kirsch R, Riddell RH, Diamandis EP. Expression patterns of bone morphogenetic protein antagonists in colorectal cancer desmoplastic invasion fronts. Molecular Oncology. 8: 1240-52. PMID 24812030 DOI: 10.1016/J.Molonc.2014.04.004  0.592
2014 Diamandis EP. Present and future of cancer biomarkers. Clinical Chemistry and Laboratory Medicine. 52: 791-4. PMID 24803613 DOI: 10.1515/Cclm-2014-0317  0.41
2014 Pavlou MP, Dimitromanolakis A, Martinez-Morillo E, Smid M, Foekens JA, Diamandis EP. Integrating meta-analysis of microarray data and targeted proteomics for biomarker identification: application in breast cancer. Journal of Proteome Research. 13: 2897-909. PMID 24799281 DOI: 10.1021/Pr500352E  0.4
2014 Musrap N, Karagiannis GS, Saraon P, Batruch I, Smith C, Diamandis EP. Proteomic analysis of cancer and mesothelial cells reveals an increase in Mucin 5AC during ovarian cancer and peritoneal interaction. Journal of Proteomics. 103: 204-15. PMID 24726482 DOI: 10.1016/J.Jprot.2014.03.042  0.791
2014 Drabovich AP, Saraon P, Jarvi K, Diamandis EP. Seminal plasma as a diagnostic fluid for male reproductive system disorders. Nature Reviews. Urology. 11: 278-88. PMID 24709963 DOI: 10.1038/Nrurol.2014.74  0.725
2014 Bery A, Leung F, Smith CR, Diamandis EP, Kulasingam V. Deciphering the ovarian cancer ascites fluid peptidome. Clinical Proteomics. 11: 13. PMID 24694173 DOI: 10.1186/1559-0275-11-13  0.386
2014 Karagiannis GS, Pavlou MP, Saraon P, Musrap N, Xie A, Batruch I, Prassas I, Dimitromanolakis A, Petraki C, Diamandis EP. In-depth proteomic delineation of the colorectal cancer exoproteome: Mechanistic insight and identification of potential biomarkers. Journal of Proteomics. 103: 121-36. PMID 24681409 DOI: 10.1016/J.Jprot.2014.03.018  0.817
2014 Oikonomopoulou K, Brinc D, Hadjisavvas A, Christofi G, Kyriacou K, Diamandis EP. The bifacial role of helminths in cancer: involvement of immune and non-immune mechanisms. Critical Reviews in Clinical Laboratory Sciences. 51: 138-48. PMID 24588712 DOI: 10.3109/10408363.2014.886180  0.338
2014 Diamandis EP. A repository for "rare" tumor markers? Clinical Chemistry and Laboratory Medicine. 52: 795-7. PMID 24516003 DOI: 10.1515/Cclm-2014-0012  0.382
2014 Prassas I, Diamandis EP. Translational researchers beware! Unreliable commercial immunoassays (ELISAs) can jeopardize your research. Clinical Chemistry and Laboratory Medicine. 52: 765-6. PMID 24497227 DOI: 10.1515/Cclm-2013-1078  0.576
2014 Dorn J, Beaufort N, Schmitt M, Diamandis EP, Goettig P, Magdolen V. Function and clinical relevance of kallikrein-related peptidases and other serine proteases in gynecological cancers. Critical Reviews in Clinical Laboratory Sciences. 51: 63-84. PMID 24490956 DOI: 10.3109/10408363.2013.865701  0.393
2014 Saraon P, Trudel D, Kron K, Dmitromanolakis A, Trachtenberg J, Bapat B, van der Kwast T, Jarvi KA, Diamandis EP. Evaluation and prognostic significance of ACAT1 as a marker of prostate cancer progression. The Prostate. 74: 372-80. PMID 24311408 DOI: 10.1002/Pros.22758  0.759
2014 Karagiannis GS, Schaeffer DF, Cho CK, Musrap N, Saraon P, Batruch I, Grin A, Mitrovic B, Kirsch R, Riddell RH, Diamandis EP. Collective migration of cancer-associated fibroblasts is enhanced by overexpression of tight junction-associated proteins claudin-11 and occludin. Molecular Oncology. 8: 178-95. PMID 24268521 DOI: 10.1016/J.Molonc.2013.10.008  0.783
2014 Bauça JM, Martínez-Morillo E, Diamandis EP. Peptidomics of urine and other biofluids for cancer diagnostics. Clinical Chemistry. 60: 1052-61. PMID 24212086 DOI: 10.1373/Clinchem.2013.211714  0.389
2014 Diamandis EP. Tumor microenvironment-released peptides: could they form the basis for an early-diagnosis breast cancer test? Clinical Chemistry. 60: 4-6. PMID 24198244 DOI: 10.1373/Clinchem.2013.216143  0.409
2014 Karagiannis GS, Saraon P, Jarvi KA, Diamandis EP. Proteomic signatures of angiogenesis in androgen-independent prostate cancer. The Prostate. 74: 260-72. PMID 24166580 DOI: 10.1002/Pros.22747  0.785
2014 Prassas I, Brinc D, Farkona S, Leung F, Dimitromanolakis A, Chrystoja CC, Brand R, Kulasingam V, Blasutig IM, Diamandis EP. False biomarker discovery due to reactivity of a commercial ELISA for CUZD1 with cancer antigen CA125. Clinical Chemistry. 60: 381-8. PMID 24097894 DOI: 10.1373/Clinchem.2013.215236  0.68
2014 Dorn J, Gkazepis A, Kotzsch M, Kremer M, Propping C, Mayer K, Mengele K, Diamandis EP, Kiechle M, Magdolen V, Schmitt M. Clinical value of protein expression of kallikrein-related peptidase 7 (KLK7) in ovarian cancer. Biological Chemistry. 395: 95-107. PMID 23999494 DOI: 10.1515/Hsz-2013-0172  0.401
2014 Eiriksson L, Millar H, Lennox G, Reade C, Leung F, Diamandis E, Kulasingam V, Murphy K, Ferguson S, Bernardini M. The usefulness of ovarian cancer risk scoring in the discrimination of an isolated pelvic mass Gynecologic Oncology. 133: 82-83. DOI: 10.1016/J.Ygyno.2014.03.221  0.311
2014 Edwards M, Dimitromanolakis A, Lau S, Bachir B, Diamandis E, Mullen B, Jarvi K. MP16-12 CORRELATION OF PROSTATIC HISTOLOGICAL INFLAMMATION CHARACTERIZED BY TYPE AND SITE WITH PROSTATE SPECIFIC ANTIGEN VALUES IN MEN WITH BENIGN FINDINGS ON PROSTATE BIOPSY Journal of Urology. 191. DOI: 10.1016/J.Juro.2014.02.585  0.313
2014 Briollais L, Xu J, Kwiatkowski M, Friedlander M, Recker F, Kuk C, Hanna S, Fleshner NE, Bapat B, Juvet T, Li H, van der Kwast TH, Diamandis EP, Zlotta AR, Ozcelik H. MP49-20 FINE-MAPPING OF THE KALLIKREIN REGION AND ITS ROLE IN PROSTATE CANCER AGGRESSIVENESS: RESULTS FROM A CANADIAN COHORT AND THE EUROPEAN RANDOMIZED STUDY FOR PROSTATE CANCER SCREENING Journal of Urology. 191. DOI: 10.1016/J.Juro.2014.02.1121  0.373
2013 Schmitt M, Magdolen V, Yang F, Kiechle M, Bayani J, Yousef GM, Scorilas A, Diamandis EP, Dorn J. Emerging clinical importance of the cancer biomarkers kallikrein-related peptidases (KLK) in female and male reproductive organ malignancies. Radiology and Oncology. 47: 319-29. PMID 24294176 DOI: 10.2478/Raon-2013-0053  0.73
2013 Drabovich AP, Dimitromanolakis A, Saraon P, Soosaipillai A, Batruch I, Mullen B, Jarvi K, Diamandis EP. Differential diagnosis of azoospermia with proteomic biomarkers ECM1 and TEX101 quantified in seminal plasma. Science Translational Medicine. 5: 212ra160. PMID 24259048 DOI: 10.1126/Scitranslmed.3006260  0.721
2013 Makawita S, Dimitromanolakis A, Soosaipillai A, Soleas I, Chan A, Gallinger S, Haun RS, Blasutig IM, Diamandis EP. Validation of four candidate pancreatic cancer serological biomarkers that improve the performance of CA19.9. Bmc Cancer. 13: 404. PMID 24007603 DOI: 10.1186/1471-2407-13-404  0.382
2013 Konvalinka A, Zhou J, Dimitromanolakis A, Drabovich AP, Fang F, Gurley S, Coffman T, John R, Zhang SL, Diamandis EP, Scholey JW. Determination of an angiotensin II-regulated proteome in primary human kidney cells by stable isotope labeling of amino acids in cell culture (SILAC). The Journal of Biological Chemistry. 288: 24834-47. PMID 23846697 DOI: 10.1074/Jbc.M113.485326  0.313
2013 Kosanam H, Prassas I, Chrystoja CC, Soleas I, Chan A, Dimitromanolakis A, Blasutig IM, Rückert F, Gruetzmann R, Pilarsky C, Maekawa M, Brand R, Diamandis EP. Laminin, gamma 2 (LAMC2): a promising new putative pancreatic cancer biomarker identified by proteomic analysis of pancreatic adenocarcinoma tissues. Molecular & Cellular Proteomics : McP. 12: 2820-32. PMID 23798558 DOI: 10.1074/Mcp.M112.023507  0.689
2013 Dorn J, Bayani J, Yousef GM, Yang F, Magdolen V, Kiechle M, Diamandis EP, Schmitt M. Clinical utility of kallikrein-related peptidases (KLK) in urogenital malignancies. Thrombosis and Haemostasis. 110: 408-22. PMID 23765253 DOI: 10.1160/Th13-03-0206  0.74
2013 Cretu D, Diamandis EP, Chandran V. Delineating the synovial fluid proteome: recent advancements and ongoing challenges in biomarker research. Critical Reviews in Clinical Laboratory Sciences. 50: 51-63. PMID 23758541 DOI: 10.3109/10408363.2013.802408  0.319
2013 Karagiannis GS, Berk A, Dimitromanolakis A, Diamandis EP. Enrichment map profiling of the cancer invasion front suggests regulation of colorectal cancer progression by the bone morphogenetic protein antagonist, gremlin-1. Molecular Oncology. 7: 826-39. PMID 23659962 DOI: 10.1016/J.Molonc.2013.04.002  0.604
2013 Oikonomopoulou K, Brinc D, Kyriacou K, Diamandis EP. Infection and cancer: revaluation of the hygiene hypothesis. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 19: 2834-41. PMID 23536438 DOI: 10.1158/1078-0432.Ccr-12-3661  0.316
2013 Leung F, Dimitromanolakis A, Kobayashi H, Diamandis EP, Kulasingam V. Folate-receptor 1 (FOLR1) protein is elevated in the serum of ovarian cancer patients Clinical Biochemistry. 46: 1462-1468. PMID 23528302 DOI: 10.1016/J.Clinbiochem.2013.03.010  0.393
2013 Pasic MD, Yousef GM, Diamandis EP. The proteomic revolution in laboratory medicine. Clinical Biochemistry. 46: 397-8. PMID 23497914 DOI: 10.1016/J.Clinbiochem.2013.02.012  0.484
2013 Saraon P, Cretu D, Musrap N, Karagiannis GS, Batruch I, Drabovich AP, van der Kwast T, Mizokami A, Morrissey C, Jarvi K, Diamandis EP. Quantitative proteomics reveals that enzymes of the ketogenic pathway are associated with prostate cancer progression. Molecular & Cellular Proteomics : McP. 12: 1589-601. PMID 23443136 DOI: 10.1074/Mcp.M112.023887  0.81
2013 Kulasingam V, Diamandis EP. Fascin-1 is a novel biomarker of aggressiveness in some carcinomas. Bmc Medicine. 11: 53. PMID 23443037 DOI: 10.1186/1741-7015-11-53  0.348
2013 Cho CK, Drabovich AP, Karagiannis GS, Martínez-Morillo E, Dason S, Dimitromanolakis A, Diamandis EP. Quantitative proteomic analysis of amniocytes reveals potentially dysregulated molecular networks in Down syndrome. Clinical Proteomics. 10: 2. PMID 23394617 DOI: 10.1186/1559-0275-10-2  0.52
2013 Kuzmanov U, Kosanam H, Diamandis EP. The sweet and sour of serological glycoprotein tumor biomarker quantification. Bmc Medicine. 11: 31. PMID 23390961 DOI: 10.1186/1741-7015-11-31  0.354
2013 Pavlou MP, Dimitromanolakis A, Diamandis EP. Coupling proteomics and transcriptomics in the quest of subtype-specific proteins in breast cancer. Proteomics. 13: 1083-95. PMID 23386393 DOI: 10.1002/Pmic.201200526  0.375
2013 Kuzmanov U, Musrap N, Kosanam H, Smith CR, Batruch I, Dimitromanolakis A, Diamandis EP. Glycoproteomic identification of potential glycoprotein biomarkers in ovarian cancer proximal fluids. Clinical Chemistry and Laboratory Medicine. 51: 1467-76. PMID 23241603 DOI: 10.1515/Cclm-2012-0642  0.404
2013 Diamandis EP, Bast RC, Lopez-Otín C. Conquering cancer in our lifetime: new diagnostic and therapeutic trends. Clinical Chemistry. 59: 1-3. PMID 23204223 DOI: 10.1373/Clinchem.2012.186940  0.366
2013 Diamandis EP, Bast RC, Gold P, Chu TM, Magnani JL. Reflection on the discovery of carcinoembryonic antigen, prostate-specific antigen, and cancer antigens CA125 and CA19-9. Clinical Chemistry. 59: 22-31. PMID 23204222 DOI: 10.1373/Clinchem.2012.187047  0.398
2013 Bayani J, Kuzmanov U, Saraon P, Fung WA, Soosaipillai A, Squire JA, Diamandis EP. Copy number and expression alterations of miRNAs in the ovarian cancer cell line OVCAR-3: impact on kallikrein 6 protein expression. Clinical Chemistry. 59: 296-305. PMID 23136250 DOI: 10.1373/Clinchem.2012.193060  0.768
2013 Eissa A, Cretu D, Soosaipillai A, Thavaneswaran A, Pellett F, Diamandis A, Cevikbas F, Steinhoff M, Diamandis EP, Gladman D, Chandran V. Serum kallikrein-8 correlates with skin activity, but not psoriatic arthritis, in patients with psoriatic disease. Clinical Chemistry and Laboratory Medicine. 51: 317-25. PMID 23096109 DOI: 10.1515/Cclm-2012-0251  0.622
2013 Sölétormos G, Duffy MJ, Hayes DF, Sturgeon CM, Barak V, Bossuyt PM, Diamandis EP, Gion M, Hyltoft-Petersen P, Lamerz RM, Nielsen DL, Sibley P, Tholander B, Tuxen MK, Bonfrer JM. Design of tumor biomarker-monitoring trials: a proposal by the European Group on Tumor Markers. Clinical Chemistry. 59: 52-9. PMID 23034139 DOI: 10.1373/Clinchem.2011.180778  0.307
2013 Chan A, Diamandis EP, Blasutig IM. Strategies for discovering novel pancreatic cancer biomarkers. Journal of Proteomics. 81: 126-34. PMID 23026552 DOI: 10.1016/J.Jprot.2012.09.025  0.391
2013 Pavlou MP, Diamandis EP, Blasutig IM. The long journey of cancer biomarkers from the bench to the clinic. Clinical Chemistry. 59: 147-57. PMID 23019307 DOI: 10.1373/Clinchem.2012.184614  0.374
2013 Konforte D, Diamandis EP. Is early detection of cancer with circulating biomarkers feasible? Clinical Chemistry. 59: 35-7. PMID 22522223 DOI: 10.1373/Clinchem.2012.184903  0.389
2013 Olkhov-Mitsel E, Kwast TVd, Kron K, Ozcelik H, Briollais L, Fleshner N, Diamandis E, Zlotta A, Bapat B. Abstract B21: Epigenetic and post-transcriptional regulation of the kallikrein gene family as a novel panel of prostate cancer biomarkers Cancer Research. 73. DOI: 10.1158/1538-7445.Cec13-B21  0.377
2013 Musrap N, Karagiannis GS, Diamandis EP. Abstract B61: Proteomic profiling of ovarian cancer and mesothelial cells reveals novel mediators implicated in the metastatic progression of ovarian cancer to the peritoneum Clinical Cancer Research. 19. DOI: 10.1158/1078-0432.Ovca13-B61  0.416
2013 Leung F, Dimitromanolakis A, Diamandis EP, Kulasingam V. Abstract A20: Integrating high-throughput technologies for the identification and validation of ovarian cancer biomarkers Clinical Cancer Research. 19. DOI: 10.1158/1078-0432.Ovca13-A20  0.387
2013 Pavlou M, Drabovich A, Dimitromanolakis A, Diamandis E. Unravelling the Effect of Estrogen on Breast Cancer Cell Proteome Using Quantitative Proteomics Annals of Oncology. 24: iii25. DOI: 10.1093/Annonc/Mdt083.5  0.329
2013 Leung F, Musrap N, Diamandis EP, Kulasingam V. Advances in mass spectrometry-based technologies to direct personalized medicine in ovarian cancer Translational Proteomics. 1: 74-86. DOI: 10.1016/J.Trprot.2013.08.001  0.39
2013 Eissa A, Diamandis EP. Kallikrein-related Peptidase 14 Handbook of Proteolytic Enzymes. 3: 2809-2813. DOI: 10.1016/B978-0-12-382219-2.00618-9  0.503
2013 Eissa A, Diamandis EP. Kallikrein-Related Peptidase 8 Handbook of Proteolytic Enzymes. 3: 2792-2798. DOI: 10.1016/B978-0-12-382219-2.00614-1  0.503
2012 Darling MR, Hashem NN, Zhang I, Mohamed AB, Fung K, Kwan K, Mara TW, Daley TD, Diamandis EP. Kallikrein-related peptidase 10 expression in salivary gland tissues and tumours. The International Journal of Biological Markers. 27: e381-8. PMID 23250777 DOI: 10.5301/Jbm.2012.10373  0.349
2012 Leung F, Diamandis EP, Kulasingam V. From bench to bedside: discovery of ovarian cancer biomarkers using high-throughput technologies in the past decade. Biomarkers in Medicine. 6: 613-25. PMID 23075239 DOI: 10.2217/Bmm.12.70  0.382
2012 Sardana G, Diamandis EP. Biomarkers for the diagnosis of new and recurrent prostate cancer. Biomarkers in Medicine. 6: 587-96. PMID 23075237 DOI: 10.2217/Bmm.12.72  0.389
2012 Karagiannis GS, Poutahidis T, Erdman SE, Kirsch R, Riddell RH, Diamandis EP. Cancer-associated fibroblasts drive the progression of metastasis through both paracrine and mechanical pressure on cancer tissue. Molecular Cancer Research : McR. 10: 1403-18. PMID 23024188 DOI: 10.1158/1541-7786.Mcr-12-0307  0.585
2012 Leung F, Soosaipillai A, Kulasingam V, Diamandis EP. CUB and zona pellucida-like domain-containing protein 1 (CUZD1): A novel serological biomarker for ovarian cancer Clinical Biochemistry. 45: 1543-1546. PMID 22985796 DOI: 10.1016/J.Clinbiochem.2012.08.011  0.408
2012 Saraon P, Musrap N, Cretu D, Karagiannis GS, Batruch I, Smith C, Drabovich AP, Trudel D, van der Kwast T, Morrissey C, Jarvi KA, Diamandis EP. Proteomic profiling of androgen-independent prostate cancer cell lines reveals a role for protein S during the development of high grade and castration-resistant prostate cancer. The Journal of Biological Chemistry. 287: 34019-31. PMID 22908226 DOI: 10.1074/Jbc.M112.384438  0.794
2012 Musrap N, Diamandis EP. Revisiting the complexity of the ovarian cancer microenvironment--clinical implications for treatment strategies. Molecular Cancer Research : McR. 10: 1254-64. PMID 22896662 DOI: 10.1158/1541-7786.Mcr-12-0353  0.337
2012 Diamandis EP. The failure of protein cancer biomarkers to reach the clinic: why, and what can be done to address the problem? Bmc Medicine. 10: 87. PMID 22876833 DOI: 10.1186/1741-7015-10-87  0.379
2012 Martínez-Morillo E, Cho CK, Drabovich AP, Shaw JL, Soosaipillai A, Diamandis EP. Development of a multiplex selected reaction monitoring assay for quantification of biochemical markers of down syndrome in amniotic fluid samples. Journal of Proteome Research. 11: 3880-7. PMID 22681384 DOI: 10.1021/Pr300355A  0.301
2012 Kuzmanov U, Smith CR, Batruch I, Soosaipillai A, Diamandis A, Diamandis EP. Separation of kallikrein 6 glycoprotein subpopulations in biological fluids by anion-exchange chromatography coupled to ELISA and identification by mass spectrometry. Proteomics. 12: 799-809. PMID 22539431 DOI: 10.1002/Pmic.201100371  0.34
2012 Drabovich AP, Pavlou MP, Dimitromanolakis A, Diamandis EP. Quantitative analysis of energy metabolic pathways in MCF-7 breast cancer cells by selected reaction monitoring assay. Molecular & Cellular Proteomics : McP. 11: 422-34. PMID 22535206 DOI: 10.1074/Mcp.M111.015214  0.345
2012 Prassas I, Chrystoja CC, Makawita S, Diamandis EP. Bioinformatic identification of proteins with tissue-specific expression for biomarker discovery. Bmc Medicine. 10: 39. PMID 22515324 DOI: 10.1186/1741-7015-10-39  0.689
2012 Ramachandran R, Eissa A, Mihara K, Oikonomopoulou K, Saifeddine M, Renaux B, Diamandis E, Hollenberg MD. Proteinase-activated receptors (PARs): differential signalling by kallikrein-related peptidases KLK8 and KLK14. Biological Chemistry. 393: 421-7. PMID 22505524 DOI: 10.1515/Hsz-2011-0251  0.583
2012 Chung H, Hamza M, Oikonomopoulou K, Gratio V, Saifeddine M, Virca GD, Diamandis EP, Hollenberg MD, Darmoul D. Kallikrein-related peptidase signaling in colon carcinoma cells: targeting proteinase-activated receptors. Biological Chemistry. 393: 413-20. PMID 22505523 DOI: 10.1515/Bc-2011-231  0.338
2012 Seiz L, Dorn J, Kotzsch M, Walch A, Grebenchtchikov NI, Gkazepis A, Schmalfeldt B, Kiechle M, Bayani J, Diamandis EP, Langer R, Sweep FCGJ, Schmitt M, Magdolen V. Stromal cell-associated expression of kallikrein-related peptidase 6 (KLK6) indicates poor prognosis of ovarian cancer patients Biological Chemistry. 393: 391-401. PMID 22505521 DOI: 10.1515/Hsz-2011-0264  0.66
2012 Petraki C, Youssef YM, Dubinski W, Lichner Z, Scorilas A, Pasic MD, Komborozos V, Khalil B, Streutker C, Diamandis EP, Yousef GM. Evaluation and prognostic significance of human tissue kallikrein-related peptidase 10 (KLK10) in colorectal cancer. Tumour Biology : the Journal of the International Society For Oncodevelopmental Biology and Medicine. 33: 1209-14. PMID 22437349 DOI: 10.1007/S13277-012-0368-5  0.557
2012 Karagiannis GS, Petraki C, Prassas I, Saraon P, Musrap N, Dimitromanolakis A, Diamandis EP. Proteomic signatures of the desmoplastic invasion front reveal collagen type XII as a marker of myofibroblastic differentiation during colorectal cancer metastasis. Oncotarget. 3: 267-85. PMID 22408128 DOI: 10.18632/Oncotarget.451  0.812
2012 McDermed JE, Sanders R, Fait S, Klem RE, Sarno MJ, Adams TH, Diamandis EP. Nucleic acid detection immunoassay for prostate-specific antigen based on immuno-PCR methodology. Clinical Chemistry. 58: 732-40. PMID 22361936 DOI: 10.1373/Clinchem.2011.170290  0.344
2012 Kagedan D, Lecker I, Batruch I, Smith C, Kaploun I, Lo K, Grober E, Diamandis EP, Jarvi KA. Characterization of the seminal plasma proteome in men with prostatitis by mass spectrometry. Clinical Proteomics. 9: 2. PMID 22309592 DOI: 10.1186/1559-0275-9-2  0.328
2012 Petraki C, Dubinski W, Scorilas A, Saleh C, Pasic MD, Komborozos V, Khalil B, Gabril MY, Streutker C, Diamandis EP, Yousef GM. Evaluation and prognostic significance of human tissue kallikrein-related peptidase 6 (KLK6) in colorectal cancer. Pathology, Research and Practice. 208: 104-8. PMID 22285222 DOI: 10.1016/J.Prp.2011.12.010  0.562
2012 Batruch I, Smith CR, Mullen BJ, Grober E, Lo KC, Diamandis EP, Jarvi KA. Analysis of seminal plasma from patients with non-obstructive azoospermia and identification of candidate biomarkers of male infertility. Journal of Proteome Research. 11: 1503-11. PMID 22188163 DOI: 10.1021/Pr200812P  0.302
2012 Bayani J, Diamandis EP. The physiology and pathobiology of human kallikrein-related peptidase 6 (KLK6) Clinical Chemistry and Laboratory Medicine. 50: 211-233. PMID 22047144 DOI: 10.1515/Cclm.2011.750  0.664
2012 Konvalinka A, Scholey JW, Diamandis EP. Searching for new biomarkers of renal diseases through proteomics Clinical Chemistry. 58: 353-365. PMID 21980170 DOI: 10.1373/Clinchem.2011.165969  0.304
2012 Rückert F, Aust D, Böhme I, Werner K, Brandt A, Diamandis EP, Krautz C, Hering S, Saeger HD, Grützmann R, Pilarsky C. Five primary human pancreatic adenocarcinoma cell lines established by the outgrowth method. The Journal of Surgical Research. 172: 29-39. PMID 21683373 DOI: 10.1016/J.Jss.2011.04.021  0.323
2012 Diamandis EP. Prostate-specific Antigen: Its Usefulness in Clinical Medicine. Trends in Endocrinology and Metabolism: Tem. 9: 310-6. PMID 18406295 DOI: 10.1016/S1043-2760(98)00082-4  0.382
2012 Saraon P, Jarvi K, Diamandis EP. Abstract C47: Quantitative mass spectrometry reveals that enzymes of the ketogenic pathway are upregulated during high-grade prostate cancer Cancer Research. 72: C47-C47. DOI: 10.1158/1538-7445.Prca2012-C47  0.774
2012 Makawita S, Dimitromanolakis A, Soosaipillai A, Soleas I, Chan A, Gallinger S, Haun RS, Blasutig I, Diamandis EP. Abstract B1: Validation of a panel of candidate pancreatic cancer serum biomarkers identifies SYCN and REG1B to significantly improve the performance of CA19.9. Cancer Research. 72. DOI: 10.1158/1538-7445.Panca2012-B1  0.391
2012 Chrystoja C, Kosanam H, Prassas I, Chan A, Dimitromanolakis A, Makawita S, Soosaipillai A, Blasutig I, Diamandis EP. Abstract A3: Validation of candidate serum biomarkers demonstrates the potential of CUZD1 and LAMC2 to complement CA19.9 for pancreatic cancer diagnosis. Cancer Research. 72. DOI: 10.1158/1538-7445.Panca2012-A3  0.688
2012 Saraon P, Jarvi K, Diamandis EP. Abstract LB-293: High-throughput proteomic analysis identifies protein s as a modulator of high grade and castrate-resistant prostate cancer Cancer Research. 72. DOI: 10.1158/1538-7445.Am2012-Lb-293  0.762
2012 Sotiropoulou G, Pampalakis G, Smith C, Zoumpourlis V, Diamandis EP. Abstract 4916: Molecular basis for the concentration-dependent tumor suppressing effects of KLK6 in breast cancer Cancer Research. 72: 4916-4916. DOI: 10.1158/1538-7445.Am2012-4916  0.397
2012 Saraon P, Cretu D, Jarvi K, Diamandis EP. Abstract 4119: High-throughput proteomics reveals that enzymes of the ketogenic pathway are upregulated during prostate cancer progression Cancer Research. 72: 4119-4119. DOI: 10.1158/1538-7445.Am2012-4119  0.776
2012 Pavlou M, Drabovich A, Dimitromanolakis A, Diamandis E. Abstract P6-05-09: Unravelling the global effect of estrogen on breast cancer cell proteome using quantitative proteomics. Cancer Research. 72. DOI: 10.1158/0008-5472.Sabcs12-P6-05-09  0.372
2012 Pavlou M, Dimitromanolakis A, Diamandis E. Abstract P2-05-11: Proteomic identification and in-silico verification of subtype-specific signatures in breast cancer. Cancer Research. 72. DOI: 10.1158/0008-5472.Sabcs12-P2-05-11  0.383
2012 Olkhov E, Van Der Kwast T, Kron K, Pethe V, Ozcelik H, Briollais L, Fleshner N, Diamandis E, Zlotta A, Bapat B. 543 Methylation of Kallikrein-related peptidases as novel diagnostic and prognostic biomarkers for prostate cancer European Urology Supplements. 11: e543-e543a. DOI: 10.1016/S1569-9056(12)60540-5  0.39
2011 Saraon P, Jarvi K, Diamandis EP. Molecular alterations during progression of prostate cancer to androgen independence. Clinical Chemistry. 57: 1366-75. PMID 21956922 DOI: 10.1373/Clinchem.2011.165977  0.744
2011 Drabovich AP, Jarvi K, Diamandis EP. Verification of male infertility biomarkers in seminal plasma by multiplex selected reaction monitoring assay Molecular &Amp; Cellular Proteomics : McP. 10. PMID 21933954 DOI: 10.1074/Mcp.M110.004127  0.314
2011 Kosanam H, Makawita S, Judd B, Newman A, Diamandis EP. Mining the malignant ascites proteome for pancreatic cancer biomarkers. Proteomics. 11: 4551-8. PMID 21932441 DOI: 10.1002/Pmic.201100264  0.41
2011 Gratio V, Loriot C, Virca GD, Oikonomopoulou K, Walker F, Diamandis EP, Hollenberg MD, Darmoul D. Kallikrein-related peptidase 14 acts on proteinase-activated receptor 2 to induce signaling pathway in colon cancer cells. The American Journal of Pathology. 179: 2625-36. PMID 21907696 DOI: 10.1016/J.Ajpath.2011.07.016  0.363
2011 Prassas I, Karagiannis GS, Batruch I, Dimitromanolakis A, Datti A, Diamandis EP. Digitoxin-induced cytotoxicity in cancer cells is mediated through distinct kinase and interferon signaling networks. Molecular Cancer Therapeutics. 10: 2083-93. PMID 21859838 DOI: 10.1158/1535-7163.Mct-11-0421  0.733
2011 Nam RK, Kattan MW, Chin JL, Trachtenberg J, Singal R, Rendon R, Klotz LH, Sugar L, Sherman C, Izawa J, Bell D, Stanimirovic A, Venkateswaran V, Diamandis EP, Yu C, et al. Prospective multi-institutional study evaluating the performance of prostate cancer risk calculators. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 29: 2959-64. PMID 21690464 DOI: 10.1200/Jco.2010.32.6371  0.354
2011 Pavlou M, Diamandis EP. I detected my cancer with my smart phone Clinical Chemistry. 57: 1221-1223. PMID 21690203 DOI: 10.1373/Clinchem.2011.165761  0.316
2011 Makawita S, Smith C, Batruch I, Zheng Y, Rückert F, Grützmann R, Pilarsky C, Gallinger S, Diamandis EP. Integrated proteomic profiling of cell line conditioned media and pancreatic juice for the identification of pancreatic cancer biomarkers. Molecular & Cellular Proteomics : McP. 10: M111.008599. PMID 21653254 DOI: 10.1074/Mcp.M111.008599  0.395
2011 Guillon-Munos A, Oikonomopoulou K, Michel N, Smith CR, Petit-Courty A, Canepa S, Reverdiau P, Heuzè-Vourc'h N, Diamandis EP, Courty Y. Kallikrein-related peptidase 12 hydrolyzes matricellular proteins of the CCN family and modifies interactions of CCN1 and CCN5 with growth factors Journal of Biological Chemistry. 286: 25505-25518. PMID 21628462 DOI: 10.1074/Jbc.M110.213231  0.304
2011 Cho CK, Drabovich AP, Batruch I, Diamandis EP. Verification of a biomarker discovery approach for detection of Down syndrome in amniotic fluid via multiplex selected reaction monitoring (SRM) assay. Journal of Proteomics. 74: 2052-9. PMID 21624510 DOI: 10.1016/J.Jprot.2011.05.025  0.314
2011 Diamandis EP, Pantel K, Scher HI, Terstappen L, Lianidou E. Circulating cancer cells and their clinical applications. Clinical Chemistry. 57: 1478-84. PMID 21586640 DOI: 10.1373/Clinchem.2011.166678  0.403
2011 Cramer DW, Bast RC, Berg CD, Diamandis EP, Godwin AK, Hartge P, Lokshin AE, Lu KH, McIntosh MW, Mor G, Patriotis C, Pinsky PF, Thornquist MD, Scholler N, Skates SJ, et al. Ovarian cancer biomarker performance in prostate, lung, colorectal, and ovarian cancer screening trial specimens. Cancer Prevention Research (Philadelphia, Pa.). 4: 365-74. PMID 21372036 DOI: 10.1158/1940-6207.Capr-10-0195  0.363
2011 Dorn J, Magdolen V, Gkazepis A, Gerte T, Harlozinska A, Sedlaczek P, Diamandis EP, Schuster T, Harbeck N, Kiechle M, Schmitt M. Circulating biomarker tissue kallikrein-related peptidase KLK5 impacts ovarian cancer patients' survival Annals of Oncology. 22: 1783-1790. PMID 21273346 DOI: 10.1200/Jco.2010.28.15_Suppl.5088  0.399
2011 Diamandis EP, Goodglick L, Planque C, Thornquist MD. Pentraxin-3 is a novel biomarker of lung carcinoma Clinical Cancer Research. 17: 2395-2399. PMID 21257721 DOI: 10.1158/1078-0432.Ccr-10-3024  0.332
2011 Batruch I, Lecker I, Kagedan D, Smith CR, Mullen BJ, Grober E, Lo KC, Diamandis EP, Jarvi KA. Proteomic analysis of seminal plasma from normal volunteers and post-vasectomy patients identifies over 2000 proteins and candidate biomarkers of the urogenital system. Journal of Proteome Research. 10: 941-53. PMID 21142078 DOI: 10.1021/Pr100745U  0.33
2011 Cho CK, Diamandis EP. Application of proteomics to prenatal screening and diagnosis for aneuploidies. Clinical Chemistry and Laboratory Medicine : Cclm / Fescc. 49: 33-41. PMID 20961197 DOI: 10.1515/Cclm.2011.002  0.301
2011 Eissa A, Amodeo V, Smith CR, Diamandis EP. Kallikrein-related peptidase-8 (KLK8) is an active serine protease in human epidermis and sweat and is involved in a skin barrier proteolytic cascade. The Journal of Biological Chemistry. 286: 687-706. PMID 20940292 DOI: 10.1074/Jbc.M110.125310  0.59
2011 Bayani J, Marrano P, Graham C, Zheng Y, Li L, Katsaros D, Lassus H, Butzow R, Squire JA, Diamandis EP. Genomic instability and copy-number heterogeneity of chromosome 19q, including the kallikrein locus, in ovarian carcinomas. Molecular Oncology. 5: 48-60. PMID 20800559 DOI: 10.1016/J.Molonc.2010.08.002  0.609
2011 Efthimiou I, Ferentinos G, Tsachouridis G, Sardana G, Diamandis E. Determination of the association of urine prostate specific antigen levels with anthropometric variables in children aged 5-14 years. International Braz J Urol : Official Journal of the Brazilian Society of Urology. 36: 202-7; discussion 20. PMID 20450506 DOI: 10.1590/S1677-55382010000200011  0.314
2011 Yousef G, Diamandis E. KLK5 (Kallikrein-related peptidase 5) Atlas of Genetics and Cytogenetics in Oncology and Haematology. DOI: 10.4267/2042/44470  0.503
2011 Saraon P, Jarvi K, Diamandis EP. Abstract LB-332: High-throughput proteomic analysis identifies protein S as a potential modulator of androgen-independent prostate cancer Cancer Research. 71. DOI: 10.1158/1538-7445.Am2011-Lb-332  0.765
2011 Karagiannis GS, Diamandis EP. Abstract LB-282: Cancer-specific motogenic signals induce collective migratory pattern in myofibroblasts via increased tight junction formation Cancer Research. 71. DOI: 10.1158/1538-7445.Am2011-Lb-282  0.328
2011 Makawita S, Smith C, Batruch I, Rueckert F, Diamandis EP. Abstract 5105: Towards a multiparametric biomarker panel for pancreatic cancer detection Cancer Research. 71: 5105-5105. DOI: 10.1158/1538-7445.Am2011-5105  0.353
2011 Makawita S, Kosanam H, Diamandis EP. Abstract 5103: Mining the pancreatic cancer ascites fluid proteome with mass spectrometry Cancer Research. 71: 5103-5103. DOI: 10.1158/1538-7445.Am2011-5103  0.376
2011 Prassas I, Makawita S, Diamandis E. Abstract 5075: An integratedin silicoand proteomic approach towards the identification of novel cancer biomarkers based on tissue specificity Cancer Research. 71: 5075-5075. DOI: 10.1158/1538-7445.Am2011-5075  0.731
2011 Karagiannis GS, Musrap N, Diamandis EP. Abstract 4923: Myofibroblasts induce specific epithelial-to-mesenchymal transition (EMT) patterns in colorectal cancer cells by enhanced secretion of bone morphogenic protein (BMP) inhibitors Cancer Research. 71: 4923-4923. DOI: 10.1158/1538-7445.Am2011-4923  0.38
2011 Saraon P, Batruch I, Smith C, Mizokami A, Jarvi K, Diamandis EP. Abstract 4870: High-throughput proteomics using stable isotope labelling with amino acids in cell culture (SILAC) reveals potential modulators of androgen-independent prostate cancers Cancer Research. 71: 4870-4870. DOI: 10.1158/1538-7445.Am2011-4870  0.764
2011 Kuzmanov U, Smith CR, Soosaipillai AR, Diamandis EP. Abstract 2223: ELISA coupled anion exchange methodology for separation of KLK6 glycoprotein subpopulations in biological fluids Cancer Research. 71: 2223-2223. DOI: 10.1158/1538-7445.Am2011-2223  0.409
2011 Bayani J, Kuzmanov U, Smith C, Batruch I, Presvelos J, Graham C, Squire JA, Diamandis EP. Abstract 1168: Integrated genomic, microRNA (miRNA) and proteomic profiling by stable isotope labeling with amino acids in cell culture (SILAC) of ovarian carcinoma for biomarker discovery Cancer Research. 71: 1168-1168. DOI: 10.1158/1538-7445.Am2011-1168  0.618
2011 Thoms J, Soosaipillai A, Christensen E, Sykes J, Pintilie M, Diamandis E, Bristow R. Human Tissue Kallikrein (KLK) Expression and IMRT Response in Intermediate Risk Prostate Cancer International Journal of Radiation Oncology*Biology*Physics. 81: S761-S762. DOI: 10.1016/J.Ijrobp.2011.06.1170  0.386
2010 Karagiannis GS, Pavlou MP, Diamandis EP. Cancer secretomics reveal pathophysiological pathways in cancer molecular oncology. Molecular Oncology. 4: 496-510. PMID 20934395 DOI: 10.1016/J.Molonc.2010.09.001  0.611
2010 Dorn J, Harbeck N, Kates R, Gkazepis A, Scorilas A, Soosaipillai A, Diamandis E, Kiechle M, Schmalfeldt B, Schmitt M. Impact of expression differences of kallikrein-related peptidases and of uPA and PAI-1 between primary tumor and omentum metastasis in advanced ovarian cancer. Annals of Oncology : Official Journal of the European Society For Medical Oncology. 22: 877-883. PMID 20924077 DOI: 10.1093/Annonc/Mdq462  0.347
2010 Diamandis EP. Cancer biomarkers: can we turn recent failures into success? Journal of the National Cancer Institute. 102: 1462-7. PMID 20705936 DOI: 10.1093/Jnci/Djq306  0.389
2010 Diamandis EP. Can chemoprevention reduce the risk of prostate cancer? Clinical Chemistry. 56: 1214-5. PMID 20567025 DOI: 10.1373/Clinchem.2010.147918  0.374
2010 Rabien A, Fritzsche FR, Jung M, Tölle A, Diamandis EP, Miller K, Jung K, Kristiansen G, Stephan C. KLK15 is a prognostic marker for progression-free survival in patients with radical prostatectomy. International Journal of Cancer. 127: 2386-94. PMID 20473923 DOI: 10.1002/Ijc.25435  0.404
2010 Cho CK, Smith CR, Diamandis EP. Amniotic fluid proteome analysis from Down syndrome pregnancies for biomarker discovery. Journal of Proteome Research. 9: 3574-82. PMID 20459121 DOI: 10.1021/Pr100088K  0.314
2010 Pavlou MP, Diamandis EP. The cancer cell secretome: a good source for discovering biomarkers? Journal of Proteomics. 73: 1896-906. PMID 20394844 DOI: 10.1016/J.Jprot.2010.04.003  0.419
2010 Kulasingam V, Pavlou MP, Diamandis EP. Integrating high-throughput technologies in the quest for effective biomarkers for ovarian cancer. Nature Reviews. Cancer. 10: 371-8. PMID 20383179 DOI: 10.1038/Nrc2831  0.374
2010 Oikonomopoulou K, Batruch I, Smith CR, Soosaipillai A, Diamandis EP, Hollenberg MD. Functional proteomics of kallikrein-related peptidases in ovarian cancer ascites fluid. Biological Chemistry. 391: 381-90. PMID 20180649 DOI: 10.1515/Bc.2010.045  0.383
2010 White NM, Bui A, Mejia-Guerrero S, Chao J, Soosaipillai A, Youssef Y, Mankaruos M, Honey RJ, Stewart R, Pace KT, Sugar L, Diamandis EP, Doré J, Yousef GM. Dysregulation of kallikrein-related peptidases in renal cell carcinoma: potential targets of miRNAs. Biological Chemistry. 391: 411-23. PMID 20180642 DOI: 10.1515/Bc.2010.041  0.535
2010 Oikonomopoulou K, Diamandis EP, Hollenberg MD. Kallikrein-related peptidases: proteolysis and signaling in cancer, the new frontier. Biological Chemistry. 391: 299-310. PMID 20180639 DOI: 10.1515/Bc.2010.038  0.337
2010 Diamandis EP. Early prostate cancer antigen-2: a controversial prostate cancer biomarker? Clinical Chemistry. 56: 542-4. PMID 20167690 DOI: 10.1373/Clinchem.2009.140061  0.389
2010 Diamandis EP. Prostate cancer screening with prostate-specific antigen testing: more answers or more confusion? Clinical Chemistry. 56: 345-51. PMID 20093554 DOI: 10.1373/Clinchem.2009.140046  0.39
2010 Drabovich AP, Diamandis EP. Combinatorial peptide libraries facilitate development of multiple reaction monitoring assays for low-abundance proteins. Journal of Proteome Research. 9: 1236-45. PMID 20070123 DOI: 10.1021/Pr900729G  0.334
2010 Kuk C, Gunawardana CG, Soosaipillai A, Kobayashi H, Li L, Zheng Y, Diamandis EP. Nidogen-2: a new serum biomarker for ovarian cancer. Clinical Biochemistry. 43: 355-61. PMID 19883638 DOI: 10.1016/J.Clinbiochem.2009.10.012  0.372
2010 Gunawardana CG, Kuk C, Smith CR, Batruch I, Soosaipillai A, Diamandis EP. Comprehensive analysis of conditioned media from ovarian cancer cell lines identifies novel candidate markers of epithelial ovarian cancer. Journal of Proteome Research. 8: 4705-13. PMID 19663500 DOI: 10.1021/Pr900411G  0.408
2010 Karagiannis GS, Cho CJ, Makawita S, Cretu D, Diamandis EP. A quantitative proteomic approach to identify key mediators of cancer progression in “tumor-host cell interaction” model systems F1000research. 1. DOI: 10.7490/F1000Research.544.1  0.334
2010 Hashem NN, Mara TW, Mohamed M, Zhang I, Fung K, Kwan KF, Daley TD, Diamandis EP, Darling MR. Human Kallikrein 14 (Klk14) Expression in Salivary Gland Tumors The International Journal of Biological Markers. 25: 32-37. DOI: 10.5301/Jbm.2010.4269  0.318
2010 Pavlou M, Sauter ER, Kliethermes B, Diamandis EP. Abstract 4574: Mining the proteome of breast cancer cell lines and nipple aspirate fluid in the quest for novel breast cancer biomarkers Cancer Research. 70: 4574-4574. DOI: 10.1158/1538-7445.Am10-4574  0.386
2010 Karagiannis GS, Diamandis EP. Abstract 4573: Discovery of candidate biomarkers for colorectal cancer using mass spectrometry-based proteomic analysis of cell line conditioned media Cancer Research. 70: 4573-4573. DOI: 10.1158/1538-7445.Am10-4573  0.398
2010 Makawita S, Smith C, Batruch I, Ruckert F, Diamandis EP. Abstract 4560: Integrative proteomic profiling of pancreatic cancer cell line supernatants, pancreatic juice and ascites fluid for the identification of novel pancreatic cancer biomarkers Cancer Research. 70: 4560-4560. DOI: 10.1158/1538-7445.Am10-4560  0.405
2010 Bayani J, Kuzmanov U, Batruch I, Cho C, Smith C, Marrano P, Graham C, Butzow R, Katsaros D, Lin L, Zheng Y, Squire JA, Diamandis EP. Abstract 3037: Integrated Genomic, MicroRNA (miRNA) and Proteomic Profiling of Ovarian Carcinoma for Biomarker Discovery Cancer Research. 70: 3037-3037. DOI: 10.1158/1538-7445.Am10-3037  0.612
2009 Makawita S, Diamandis EP. The bottleneck in the cancer biomarker pipeline and protein quantification through mass spectrometry-based approaches: current strategies for candidate verification. Clinical Chemistry. 56: 212-22. PMID 20007861 DOI: 10.1373/Clinchem.2009.127019  0.37
2009 Sotiropoulou G, Pampalakis G, Diamandis EP. Functional roles of human kallikrein-related peptidases. The Journal of Biological Chemistry. 284: 32989-94. PMID 19819870 DOI: 10.1074/Jbc.R109.027946  0.337
2009 Pampalakis G, Diamandis EP, Katsaros D, Sotiropoulou G. Down-regulation of dicer expression in ovarian cancer tissues. Clinical Biochemistry. 43: 324-7. PMID 19782670 DOI: 10.1016/J.Clinbiochem.2009.09.014  0.373
2009 Planque C, Kulasingam V, Smith CR, Reckamp K, Goodglick L, Diamandis EP. Identification of five candidate lung cancer biomarkers by proteomics analysis of conditioned media of four lung cancer cell lines. Molecular & Cellular Proteomics : McP. 8: 2746-58. PMID 19776420 DOI: 10.1074/Mcp.M900134-Mcp200  0.358
2009 Yousef GM, Diamandis EP. The human kallikrein gene family: new biomarkers for ovarian cancer. Cancer Treatment and Research. 149: 165-87. PMID 19763436 DOI: 10.1007/978-0-387-98094-2_8  0.541
2009 Christensen E, Pintilie M, Evans KR, Lenarduzzi M, Ménard C, Catton CN, Diamandis EP, Bristow RG. Longitudinal cytokine expression during IMRT for prostate cancer and acute treatment toxicity. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 15: 5576-83. PMID 19706801 DOI: 10.1158/1078-0432.Ccr-09-0245  0.4
2009 Oikonomopoulou K, Soosaipillai A, Diamandis EP. Evaluation of prostate-specific antigen as a novel biomarker of Hsp90 inhibition. Clinical Biochemistry. 42: 1705-12. PMID 19632215 DOI: 10.1016/J.Clinbiochem.2009.07.018  0.346
2009 Sardana G, Diamandis EP. The kallikrein family of proteins as urinary biomarkers for the detection of prostate cancer. Clinical Biochemistry. 42: 1483-6. PMID 19560453 DOI: 10.1016/J.Clinbiochem.2009.06.015  0.399
2009 Pavlou M, Diamandis EP. The search for new prostate cancer biomarkers continues. Clinical Chemistry. 55: 1277-9. PMID 19478024 DOI: 10.1373/Clinchem.2009.126870  0.395
2009 Talieri M, Li L, Zheng Y, Alexopoulou DK, Soosaipillai A, Scorilas A, Xynopoulos D, Diamandis EP. The use of kallikrein-related peptidases as adjuvant prognostic markers in colorectal cancer. British Journal of Cancer. 100: 1659-65. PMID 19367279 DOI: 10.1038/Sj.Bjc.6605033  0.372
2009 Talieri M, Mathioudaki K, Prezas P, Alexopoulou DK, Diamandis EP, Xynopoulos D, Ardavanis A, Arnogiannaki N, Scorilas A. Clinical significance of kallikrein-related peptidase 7 (KLK7) in colorectal cancer. Thrombosis and Haemostasis. 101: 741-7. PMID 19350120 DOI: 10.1160/Th08-07-0471  0.435
2009 Kulasingam V, Zheng Y, Soosaipillai A, Leon AE, Gion M, Diamandis EP. Activated leukocyte cell adhesion molecule: a novel biomarker for breast cancer. International Journal of Cancer. Journal International Du Cancer. 125: 9-14. PMID 19322904 DOI: 10.1002/Ijc.24292  0.351
2009 Shaw JL, Petraki C, Watson C, Bocking A, Diamandis EP. Role of tissue kallikrein-related peptidases in cervical mucus remodeling and host defense. Biological Chemistry. 389: 1513-22. PMID 18844451 DOI: 10.1515/Bc.2008.171  0.328
2009 Scorilas A, Markakis S, Kowalski D, Camp RL, Diamandis EP, Dimopoulos MA, Kountourakis P, Psyrri A. Expression and prognostic significance of kallikrein-related peptidase 8 protein levels in advanced ovarian cancer by using automated quantitative analysis Thrombosis and Haemostasis. 101: 541-546. DOI: 10.1160/Th08-01-0052  0.38
2009 Pavlou M, Diamandis E. Delineating the Secretome of Eleven Breast Cell Lines in the Quest for Novel Breast Cancer Biomarkers. Cancer Research. 69: 2137-2137. DOI: 10.1158/0008-5472.Sabcs-09-2137  0.361
2009 Barak V, Sherman Y, Doviner V, Edelman D, Diamandis E. New Kallikrein markers for ovarian cancers Biomedicine & Pharmacotherapy. 63: 329-330. DOI: 10.1016/J.Biopha.2009.04.027  0.367
2008 Darling MR, Tsai S, Jackson-Boeters L, Daley TD, Diamandis EP. Human kallikrein 8 expression in salivary gland tumors. Head and Neck Pathology. 2: 169-74. PMID 20614312 DOI: 10.1007/S12105-008-0068-Z  0.352
2008 Bayani J, Paliouras M, Planque C, Shan SJ, Graham C, Squire JA, Diamandis EP. Impact of cytogenetic and genomic aberrations of the kallikrein locus in ovarian cancer. Molecular Oncology. 2: 250-60. PMID 19383346 DOI: 10.1016/J.Molonc.2008.07.001  0.648
2008 Paliouras M, Diamandis EP. Androgens act synergistically to enhance estrogen-induced upregulation of human tissue kallikreins 10, 11, and 14 in breast cancer cells via a membrane bound androgen receptor. Molecular Oncology. 1: 413-24. PMID 19383315 DOI: 10.1016/J.Molonc.2008.01.001  0.369
2008 Gunawardana CG, Memari N, Diamandis EP. Identifying novel autoantibody signatures in ovarian cancer using high-density protein microarrays. Clinical Biochemistry. 42: 426-9. PMID 19094976 DOI: 10.1016/J.Clinbiochem.2008.11.008  0.381
2008 Kuzmanov U, Jiang N, Smith CR, Soosaipillai A, Diamandis EP. Differential N-glycosylation of kallikrein 6 derived from ovarian cancer cells or the central nervous system. Molecular & Cellular Proteomics : McP. 8: 791-8. PMID 19088065 DOI: 10.1074/Mcp.M800516-Mcp200  0.399
2008 Kuk C, Kulasingam V, Gunawardana CG, Smith CR, Batruch I, Diamandis EP. Mining the ovarian cancer ascites proteome for potential ovarian cancer biomarkers. Molecular & Cellular Proteomics : McP. 8: 661-9. PMID 19047685 DOI: 10.1074/Mcp.M800313-Mcp200  0.397
2008 Sturgeon CM, Duffy MJ, Stenman UH, Lilja H, Brünner N, Chan DW, Babaian R, Bast RC, Dowell B, Esteva FJ, Haglund C, Harbeck N, Hayes DF, Holten-Andersen M, Klee GG, ... ... Diamandis EP, et al. National Academy of Clinical Biochemistry laboratory medicine practice guidelines for use of tumor markers in testicular, prostate, colorectal, breast, and ovarian cancers. Clinical Chemistry. 54: e11-79. PMID 19042984 DOI: 10.1373/Clinchem.2008.105601  0.325
2008 Shaw JL, Diamandis EP. Regulation of human tissue kallikrein-related peptidase expression by steroid hormones in 32 cell lines. Biological Chemistry. 389: 1409-19. PMID 19031603 DOI: 10.1515/Bc.2008.158  0.395
2008 Kountourakis P, Psyrri A, Scorilas A, Camp R, Markakis S, Kowalski D, Diamandis EP, Dimopoulos MA. Prognostic value of kallikrein-related peptidase 6 protein expression levels in advanced ovarian cancer evaluated by automated quantitative analysis (AQUA). Cancer Science. 99: 2224-9. PMID 18957059 DOI: 10.1111/J.1349-7006.2008.00942.X  0.407
2008 Prassas I, Diamandis EP. Novel therapeutic applications of cardiac glycosides. Nature Reviews. Drug Discovery. 7: 926-35. PMID 18948999 DOI: 10.1038/Nrd2682  0.63
2008 Sardana G, Dowell B, Diamandis EP. Emerging biomarkers for the diagnosis and prognosis of prostate cancer. Clinical Chemistry. 54: 1951-60. PMID 18927246 DOI: 10.1373/Clinchem.2008.110668  0.394
2008 Prassas I, Paliouras M, Datti A, Diamandis EP. High-throughput screening identifies cardiac glycosides as potent inhibitors of human tissue kallikrein expression: implications for cancer therapies. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 14: 5778-84. PMID 18794087 DOI: 10.1158/1078-0432.Ccr-08-0706  0.694
2008 Oikonomopoulou K, Li L, Zheng Y, Simon I, Wolfert RL, Valik D, Nekulova M, Simickova M, Frgala T, Diamandis EP. Prediction of ovarian cancer prognosis and response to chemotherapy by a serum-based multiparametric biomarker panel. British Journal of Cancer. 99: 1103-13. PMID 18766180 DOI: 10.1038/Sj.Bjc.6604630  0.336
2008 Kulasingam V, Diamandis EP. Tissue culture-based breast cancer biomarker discovery platform. International Journal of Cancer. 123: 2007-12. PMID 18712711 DOI: 10.1002/Ijc.23844  0.421
2008 Kulasingam V, Diamandis EP. Strategies for discovering novel cancer biomarkers through utilization of emerging technologies. Nature Clinical Practice. Oncology. 5: 588-99. PMID 18695711 DOI: 10.1038/Ncponc1187  0.37
2008 Emami N, Diamandis EP. Utility of kallikrein-related peptidases (KLKs) as cancer biomarkers. Clinical Chemistry. 54: 1600-7. PMID 18687738 DOI: 10.1373/Clinchem.2008.105189  0.438
2008 Paliouras M, Diamandis EP. An AKT activity threshold regulates androgen-dependent and androgen-independent PSA expression in prostate cancer cell lines. Biological Chemistry. 389: 773-80. PMID 18627304 DOI: 10.1515/Bc.2008.072  0.393
2008 Planque C, Bléchet C, Ayadi-Kaddour A, Heuzé-Vourc'h N, Dumont P, Guyétant S, Diamandis EP, El Mezni F, Courty Y. Quantitative RT-PCR analysis and immunohistochemical localization of the kallikrein-related peptidases 13 and 14 in lung. Biological Chemistry. 389: 781-6. PMID 18627302 DOI: 10.1515/Bc.2008.089  0.33
2008 Eissa A, Diamandis EP. Human tissue kallikreins as promiscuous modulators of homeostatic skin barrier functions. Biological Chemistry. 389: 669-80. PMID 18627299 DOI: 10.1515/Bc.2008.079  0.586
2008 Shaw JL, Diamandis EP. A potential role for tissue kallikrein-related peptidases in human cervico-vaginal physiology. Biological Chemistry. 389: 681-8. PMID 18627298 DOI: 10.1515/Bc.2008.069  0.338
2008 Hollenberg MD, Oikonomopoulou K, Hansen KK, Saifeddine M, Ramachandran R, Diamandis EP. Kallikreins and proteinase-mediated signaling: proteinase-activated receptors (PARs) and the pathophysiology of inflammatory diseases and cancer. Biological Chemistry. 389: 643-51. PMID 18627296 DOI: 10.1515/Bc.2008.077  0.316
2008 Oikonomopoulou K, Hansen KK, Baruch A, Hollenberg MD, Diamandis EP. Immunofluorometric activity-based probe analysis of active KLK6 in biological fluids. Biological Chemistry. 389: 747-56. PMID 18627291 DOI: 10.1515/Bc.2008.086  0.385
2008 Chow TF, Crow M, Earle T, El-Said H, Diamandis EP, Yousef GM. Kallikreins as microRNA targets: an in silico and experimental-based analysis. Biological Chemistry. 389: 731-8. PMID 18627289 DOI: 10.1515/Bc.2008.071  0.504
2008 Sardana G, Jung K, Stephan C, Diamandis EP. Proteomic analysis of conditioned media from the PC3, LNCaP, and 22Rv1 prostate cancer cell lines: discovery and validation of candidate prostate cancer biomarkers. Journal of Proteome Research. 7: 3329-38. PMID 18578523 DOI: 10.1021/Pr8003216  0.426
2008 Paliouras M, Diamandis EP. Intracellular signaling pathways regulate hormone-dependent kallikrein gene expression. Tumour Biology : the Journal of the International Society For Oncodevelopmental Biology and Medicine. 29: 63-75. PMID 18515984 DOI: 10.1159/000135686  0.322
2008 Rabien A, Fritzsche F, Jung M, Diamandis EP, Loening SA, Dietel M, Jung K, Stephan C, Kristiansen G. High expression of KLK14 in prostatic adenocarcinoma is associated with elevated risk of prostate-specific antigen relapse. Tumour Biology : the Journal of the International Society For Oncodevelopmental Biology and Medicine. 29: 1-8. PMID 18497543 DOI: 10.1159/000132565  0.399
2008 Emami N, Deperthes D, Malm J, Diamandis EP. Major role of human KLK14 in seminal clot liquefaction. The Journal of Biological Chemistry. 283: 19561-9. PMID 18482984 DOI: 10.1074/Jbc.M801194200  0.329
2008 Psyrri A, Kountourakis P, Scorilas A, Markakis S, Camp R, Diamandis EP, Dimopoulos MA, Kowalski D. Human tissue kallikrein 7, a novel biomarker for advanced ovarian carcinoma using a novel in situ quantitative method of protein expression. Annals of Oncology : Official Journal of the European Society For Medical Oncology. 19: 1271-1277. PMID 18325919 DOI: 10.1093/Annonc/Mdn035  0.412
2008 Planque C, Li L, Zheng Y, Soosaipillai A, Reckamp K, Chia D, Diamandis EP, Goodglick L. A multiparametric serum kallikrein panel for diagnosis of non-small cell lung carcinoma. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 14: 1355-62. PMID 18316555 DOI: 10.1158/1078-0432.Ccr-07-4117  0.347
2008 Kulasingam V, Smith CR, Batruch I, Buckler A, Jeffery DA, Diamandis EP. "Product ion monitoring" assay for prostate-specific antigen in serum using a linear ion-trap. Journal of Proteome Research. 7: 640-7. PMID 18186600 DOI: 10.1021/Pr7005999  0.321
2008 Maki J, Robinson K, Reguly B, Alexander J, Wittock R, Aguirre A, Diamandis EP, Escott N, Skehan A, Prowse O, Thayer RE, Froberg MK, Wilson MJ, Maragh S, Jakupciak JP, et al. Mitochondrial genome deletion aids in the identification of false- and true-negative prostate needle core biopsy specimens. American Journal of Clinical Pathology. 129: 57-66. PMID 18089489 DOI: 10.1309/Ujjth4Hfepwaq78Q  0.344
2008 Rabien A, Kristiansen G, Diamandis EP, Jung K, Stephan C. [Human kallikreins as tumor markers. Validation of potential marker of prostate cancer in serum and tissue]. Der Urologe. Ausg. A. 46: 1070-1. PMID 17605120 DOI: 10.1007/S00120-007-1420-8  0.408
2007 Forrester S, Qiu J, Mangold L, Partin A, Misek D, Phinney B, Whitten D, Andrews P, Diamandis E, Omenn GS, Hanash S, Haab BB. An experimental strategy for quantitative analysis of the humoral immune response to prostate cancer antigens using natural protein microarrays. Proteomics. Clinical Applications. 1: 494-505. PMID 21136701 DOI: 10.1002/Prca.200600802  0.424
2007 Emami N, Diamandis EP. New insights into the functional mechanisms and clinical applications of the kallikrein-related peptidase family. Molecular Oncology. 1: 269-87. PMID 19383303 DOI: 10.1016/J.Molonc.2007.09.003  0.305
2007 Yousef GM, Denic N, Wadhwa J, Chandracanth SA, Smith T, Elms F, Diamandis EP. Intravagal ectopic parathyroid presenting as vocal cord paralysis: case report and review of the literature. The Journal of Otolaryngology. 36: E93-5. PMID 18076837  0.378
2007 Zheng Y, Katsaros D, Shan SJ, de la Longrais IR, Porpiglia M, Scorilas A, Kim NW, Wolfert RL, Simon I, Li L, Feng Z, Diamandis EP. A multiparametric panel for ovarian cancer diagnosis, prognosis, and response to chemotherapy. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 13: 6984-92. PMID 18056174 DOI: 10.1158/1078-0432.Ccr-07-1409  0.355
2007 Diamandis EP. POINT: EPCA-2: a promising new serum biomarker for prostatic carcinoma? Clinical Biochemistry. 40: 1437-9. PMID 17945209 DOI: 10.1016/J.Clinbiochem.2007.09.003  0.328
2007 Stephan C, Jung K, Lein M, Diamandis EP. PSA and other tissue kallikreins for prostate cancer detection. European Journal of Cancer (Oxford, England : 1990). 43: 1918-26. PMID 17689069 DOI: 10.1016/J.Ejca.2007.06.006  0.39
2007 McIntosh MW, Liu Y, Drescher C, Urban N, Diamandis EP. Validation and characterization of human kallikrein 11 as a serum marker for diagnosis of ovarian carcinoma Clinical Cancer Research. 13: 4422-4428. PMID 17671125 DOI: 10.1158/1078-0432.Ccr-06-2224  0.345
2007 Kulasingam V, Diamandis EP. Proteomics analysis of conditioned media from three breast cancer cell lines: a mine for biomarkers and therapeutic targets. Molecular & Cellular Proteomics : McP. 6: 1997-2011. PMID 17656355 DOI: 10.1074/Mcp.M600465-Mcp200  0.376
2007 Memari N, Diamandis EP, Earle T, Campbell A, Van Dekken H, Van der Kwast TH. Human kallikrein-related peptidase 12: antibody generation and immunohistochemical localization in prostatic tissues. The Prostate. 67: 1465-74. PMID 17654496 DOI: 10.1002/Pros.20596  0.396
2007 Shaw JL, Diamandis EP. Distribution of 15 human kallikreins in tissues and biological fluids. Clinical Chemistry. 53: 1423-32. PMID 17573418 DOI: 10.1373/Clinchem.2007.088104  0.359
2007 Shaw JL, Smith CR, Diamandis EP. Proteomic analysis of human cervico-vaginal fluid. Journal of Proteome Research. 6: 2859-65. PMID 17567164 DOI: 10.1021/Pr0701658  0.326
2007 Komatsu N, Saijoh K, Kuk C, Liu AC, Khan S, Shirasaki F, Takehara K, Diamandis EP. Human tissue kallikrein expression in the stratum corneum and serum of atopic dermatitis patients. Experimental Dermatology. 16: 513-9. PMID 17518992 DOI: 10.1111/J.1600-0625.2007.00562.X  0.305
2007 Diamandis EP. Oncopeptidomics: a useful approach for cancer diagnosis? Clinical Chemistry. 53: 1004-6. PMID 17517585 DOI: 10.1373/Clinchem.2006.082552  0.395
2007 Simon I, Katsaros D, Rigault de la Longrais I, Massobrio M, Scorilas A, Kim NW, Sarno MJ, Wolfert RL, Diamandis EP. B7-H4 is over-expressed in early-stage ovarian cancer and is independent of CA125 expression. Gynecologic Oncology. 106: 334-41. PMID 17498784 DOI: 10.1016/J.Ygyno.2007.03.035  0.336
2007 Cho CK, Shan SJ, Winsor EJ, Diamandis EP. Proteomics analysis of human amniotic fluid. Molecular & Cellular Proteomics : McP. 6: 1406-15. PMID 17495049 DOI: 10.1074/Mcp.M700090-Mcp200  0.301
2007 Komatsu N, Saijoh K, Kuk C, Shirasaki F, Takehara K, Diamandis EP. Aberrant human tissue kallikrein levels in the stratum corneum and serum of patients with psoriasis: dependence on phenotype, severity and therapy. The British Journal of Dermatology. 156: 875-83. PMID 17459012 DOI: 10.1111/J.1365-2133.2006.07743.X  0.33
2007 Memari N, Jiang W, Diamandis EP, Luo LY. Enzymatic properties of human kallikrein-related peptidase 12 (KLK12). Biological Chemistry. 388: 427-35. PMID 17391064 DOI: 10.1515/Bc.2007.049  0.345
2007 Emami N, Diamandis EP. Human tissue kallikreins: a road under construction. Clinica Chimica Acta; International Journal of Clinical Chemistry. 381: 78-84. PMID 17382920 DOI: 10.1016/J.Cca.2007.02.023  0.325
2007 Dorn J, Schmitt M, Kates R, Schmalfeldt B, Kiechle M, Scorilas A, Diamandis EP, Harbeck N. Primary tumor levels of human tissue kallikreins affect surgical success and survival in ovarian cancer patients. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 13: 1742-8. PMID 17363527 DOI: 10.1158/1078-0432.Ccr-06-2482  0.365
2007 Stephan C, Xu C, Cammann H, Graefen M, Haese A, Huland H, Semjonow A, Diamandis EP, Remzi M, Djavan B, Wildhagen MF, Blijenberg BG, Finne P, Stenman UH, Jung K, et al. Assay-specific artificial neural networks for five different PSA assays and populations with PSA 2-10 ng/ml in 4,480 men. World Journal of Urology. 25: 95-103. PMID 17333205 DOI: 10.1007/S00345-006-0132-9  0.314
2007 Gunawardana CG, Diamandis EP. High throughput proteomic strategies for identifying tumour-associated antigens. Cancer Letters. 249: 110-9. PMID 17306453 DOI: 10.1016/J.Canlet.2007.01.002  0.339
2007 Shih IeM, Salani R, Fiegl M, Wang TL, Soosaipillai A, Marth C, Müller-Holzner E, Gastl G, Zhang Z, Diamandis EP. Ovarian cancer specific kallikrein profile in effusions. Gynecologic Oncology. 105: 501-7. PMID 17303231 DOI: 10.1016/J.Ygyno.2007.01.018  0.391
2007 Paliouras M, Borgono C, Diamandis EP. Human tissue kallikreins: the cancer biomarker family. Cancer Letters. 249: 61-79. PMID 17275179 DOI: 10.1016/J.Canlet.2006.12.018  0.464
2007 Sardana G, Marshall J, Diamandis EP. Discovery of candidate tumor markers for prostate cancer via proteomic analysis of cell culture-conditioned medium. Clinical Chemistry. 53: 429-37. PMID 17259234 DOI: 10.1373/Clinchem.2006.077370  0.392
2007 Shan SJ, Scorilas A, Katsaros D, Diamandis EP. Transcriptional upregulation of human tissue kallikrein 6 in ovarian cancer: clinical and mechanistic aspects. British Journal of Cancer. 96: 362-72. PMID 17242704 DOI: 10.1038/Sj.Bjc.6603556  0.402
2007 Darling MR, Tsai S, Jackson-Boeters L, Daley TD, Diamandis EP. Human kallikrein 3 (prostate specific antigen) and human kallikrein 5 expression in salivary gland tumors. The International Journal of Biological Markers. 21: 201-5. PMID 17177156 DOI: 10.5301/Jbm.2008.2048  0.387
2007 van der Merwe DE, Oikonomopoulou K, Marshall J, Diamandis EP. Mass spectrometry: uncovering the cancer proteome for diagnostics. Advances in Cancer Research. 96: 23-50. PMID 17161675 DOI: 10.1016/S0065-230X(06)96002-3  0.384
2007 Borgoño CA, Michael IP, Shaw JL, Luo LY, Ghosh MC, Soosaipillai A, Grass L, Katsaros D, Diamandis EP. Expression and functional characterization of the cancer-related serine protease, human tissue kallikrein 14. The Journal of Biological Chemistry. 282: 2405-22. PMID 17110383 DOI: 10.1074/Jbc.M608348200  0.426
2007 Kountourakis P, Psyrri A, Scorilas A, Markakis S, Kowalski D, Camp RL, Diamandis EP, Dimopoulos MA. Evaluation of the prognostic significance of human kallikrein 8 protein expression levels in advanced ovarian cancer by using automated quantitative protein analysis Journal of Clinical Oncology. 25: 5581-5581. DOI: 10.1200/Jco.2007.25.18_Suppl.5581  0.404
2007 Rabien A, Fritzsche F, Jung M, Diamandis E, Loening S, Jung K, Kristiansen G, Stephan C. 105 HIGH EXPRESSION LEVELS OF THE HUMAN KALLIKREIN-LIKE PEPTIDASES KLK14 AND KLK 15 IN PROSTATIC ADENOCARCINOMA ARE ASSOCIATED WITH ELEVATED RISK OF PROSTATE-SPECIFIC ANTIGEN RELAPSE European Urology Supplements. 6: 49. DOI: 10.1016/S1569-9056(07)60104-3  0.343
2006 Prezas P, Scorilas A, Yfanti C, Viktorov P, Agnanti N, Diamandis E, Talieri M. The role of human tissue kallikreins 7 and 8 in intracranial malignancies. Biological Chemistry. 387: 1607-12. PMID 17132107 DOI: 10.1515/Bc.2006.200  0.397
2006 Shaw JL, Grass L, Sotiropoulou G, Diamandis EP. Development of an immunofluorometric assay for human kallikrein 15 (KLK15) and identification of KLK15 in tissues and biological fluids. Clinical Biochemistry. 40: 104-10. PMID 17045982 DOI: 10.1016/J.Clinbiochem.2006.07.011  0.413
2006 Diamandis EP. Peptidomics for cancer diagnosis: present and future. Journal of Proteome Research. 5: 2079-82. PMID 16944917 DOI: 10.1021/Pr060225U  0.358
2006 Shan SJ, Scorilas A, Katsaros D, Rigault de la Longrais I, Massobrio M, Diamandis EP. Unfavorable prognostic value of human kallikrein 7 quantified by ELISA in ovarian cancer cytosols. Clinical Chemistry. 52: 1879-86. PMID 16916986 DOI: 10.1373/Clinchem.2006.071456  0.418
2006 Paliouras M, Diamandis EP. Coordinated steroid hormone-dependent and independent expression of multiple kallikreins in breast cancer cell lines. Breast Cancer Research and Treatment. 102: 7-18. PMID 16897430 DOI: 10.1007/S10549-006-9312-Y  0.381
2006 Dorn J, Harbeck N, Kates R, Magdolen V, Grass L, Soosaipillai A, Schmalfeldt B, Diamandis EP, Schmitt M. Disease processes may be reflected by correlations among tissue kallikrein proteases but not with proteolytic factors uPA and PAI-1 in primary ovarian carcinoma. Biological Chemistry. 387: 1121-8. PMID 16895483 DOI: 10.1515/Bc.2006.138  0.374
2006 Luo LY, Soosaipillai A, Grass L, Diamandis EP. Characterization of human kallikreins 6 and 10 in ascites fluid from ovarian cancer patients. Tumour Biology : the Journal of the International Society For Oncodevelopmental Biology and Medicine. 27: 227-34. PMID 16864975 DOI: 10.1159/000094693  0.397
2006 Parr RL, Dakubo GD, Crandall KA, Maki J, Reguly B, Aguirre A, Wittock R, Robinson K, Alexander JS, Birch-Machin MA, Abdel-Malak M, Froberg MK, Diamandis EP, Thayer RE. Somatic mitochondrial DNA mutations in prostate cancer and normal appearing adjacent glands in comparison to age-matched prostate samples without malignant histology. The Journal of Molecular Diagnostics : Jmd. 8: 312-9. PMID 16825503 DOI: 10.2353/Jmoldx.2006.050112  0.332
2006 Prezas P, Arlt MJ, Viktorov P, Soosaipillai A, Holzscheiter L, Schmitt M, Talieri M, Diamandis EP, Krüger A, Magdolen V. Overexpression of the human tissue kallikrein genes KLK4, 5, 6, and 7 increases the malignant phenotype of ovarian cancer cells. Biological Chemistry. 387: 807-11. PMID 16800744 DOI: 10.1515/Bc.2006.102  0.405
2006 Stephan C, Meyer HA, Cammann H, Nakamura T, Diamandis EP, Jung K. Improved prostate cancer detection with a human kallikrein 11 and percentage free PSA-based artificial neural network. Biological Chemistry. 387: 801-5. PMID 16800743 DOI: 10.1515/Bc.2006.101  0.356
2006 Pampalakis G, Diamandis EP, Sotiropoulou G. The epigenetic basis for the aberrant expression of kallikreins in human cancers. Biological Chemistry. 387: 795-9. PMID 16800742 DOI: 10.1515/Bc.2006.100  0.415
2006 Obiezu CV, Michael IP, Levesque MA, Diamandis EP. Human kallikrein 4: enzymatic activity, inhibition, and degradation of extracellular matrix proteins. Biological Chemistry. 387: 749-59. PMID 16800736 DOI: 10.1515/Bc.2006.094  0.342
2006 Memari N, Grass L, Nakamura T, Karakucuk I, Diamandis EP. Human tissue kallikrein 9: production of recombinant proteins and specific antibodies. Biological Chemistry. 387: 733-40. PMID 16800734 DOI: 10.1515/Bc.2006.092  0.406
2006 Petraki CD, Papanastasiou PA, Karavana VN, Diamandis EP. Cellular distribution of human tissue kallikreins: immunohistochemical localization. Biological Chemistry. 387: 653-63. PMID 16800726 DOI: 10.1515/Bc.2006.084  0.327
2006 Paliouras M, Diamandis EP. The kallikrein world: an update on the human tissue kallikreins. Biological Chemistry. 387: 643-52. PMID 16800725 DOI: 10.1515/Bc.2006.083  0.375
2006 Lundwall A, Band V, Blaber M, Clements JA, Courty Y, Diamandis EP, Fritz H, Lilja H, Malm J, Maltais LJ, Olsson AY, Petraki C, Scorilas A, Sotiropoulou G, Stenman UH, et al. A comprehensive nomenclature for serine proteases with homology to tissue kallikreins. Biological Chemistry. 387: 637-41. PMID 16800724 DOI: 10.1515/Bc.2006.082  0.533
2006 Slagter MH, Scorilas A, Gooren LJ, de Ronde W, Soosaipillai A, Giltay EJ, Paliouras M, Diamandis EP. Effect of testosterone administration on serum and urine kallikrein concentrations in female-to-male transsexuals. Clinical Chemistry. 52: 1546-51. PMID 16777918 DOI: 10.1373/Clinchem.2006.067041  0.306
2006 Felber LM, Kündig C, Borgoño CA, Chagas JR, Tasinato A, Jichlinski P, Gygi CM, Leisinger HJ, Diamandis EP, Deperthes D, Cloutier SM. Mutant recombinant serpins as highly specific inhibitors of human kallikrein 14. The Febs Journal. 273: 2505-14. PMID 16704423 DOI: 10.1111/J.1742-4658.2006.05257.X  0.327
2006 Slagter MH, Gooren LJ, de Ronde W, Soosaipillai A, Scorilas A, Giltay EJ, Paliouras M, Diamandis EP. Serum and urine tissue kallikrein concentrations in male-to-female transsexuals treated with antiandrogens and estrogens. Clinical Chemistry. 52: 1356-65. PMID 16644872 DOI: 10.1373/Clinchem.2006.068932  0.322
2006 Stephan C, Jung K, Nakamura T, Yousef GM, Kristiansen G, Diamandis EP. Serum human glandular kallikrein 2 (hK2) for distinguishing stage and grade of prostate cancer. International Journal of Urology : Official Journal of the Japanese Urological Association. 13: 238-43. PMID 16643616 DOI: 10.1111/J.1442-2042.2006.01276.X  0.586
2006 Diamandis EP. Validation of breast cancer biomarkers identified by mass spectrometry. Clinical Chemistry. 52: 771-2; author reply . PMID 16595832 DOI: 10.1373/Clinchem.2005.064972  0.347
2006 Oikonomopoulou K, Scorilas A, Michael IP, Grass L, Soosaipillai A, Rosen B, Murphy J, Diamandis EP. Kallikreins as markers of disseminated tumour cells in ovarian cancer-- a pilot study. Tumour Biology : the Journal of the International Society For Oncodevelopmental Biology and Medicine. 27: 104-14. PMID 16557045 DOI: 10.1159/000092325  0.399
2006 Borgoño CA, Kishi T, Scorilas A, Harbeck N, Dorn J, Schmalfeldt B, Schmitt M, Diamandis EP. Human kallikrein 8 protein is a favorable prognostic marker in ovarian cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 12: 1487-93. PMID 16533772 DOI: 10.1158/1078-0432.Ccr-05-2106  0.368
2006 Michael IP, Pampalakis G, Mikolajczyk SD, Malm J, Sotiropoulou G, Diamandis EP. Human tissue kallikrein 5 is a member of a proteolytic cascade pathway involved in seminal clot liquefaction and potentially in prostate cancer progression. The Journal of Biological Chemistry. 281: 12743-50. PMID 16517595 DOI: 10.1074/Jbc.M600326200  0.387
2006 Luo LY, Shan SJ, Elliott MB, Soosaipillai A, Diamandis EP. Purification and characterization of human kallikrein 11, a candidate prostate and ovarian cancer biomarker, from seminal plasma. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 12: 742-50. PMID 16467084 DOI: 10.1158/1078-0432.Ccr-05-1696  0.406
2006 Simon I, Zhuo S, Corral L, Diamandis EP, Sarno MJ, Wolfert RL, Kim NW. B7-h4 is a novel membrane-bound protein and a candidate serum and tissue biomarker for ovarian cancer. Cancer Research. 66: 1570-5. PMID 16452214 DOI: 10.1158/0008-5472.Can-04-3550  0.363
2006 Brown DA, Stephan C, Ward RL, Law M, Hunter M, Bauskin AR, Amin J, Jung K, Diamandis EP, Hampton GM, Russell PJ, Giles GG, Breit SN. Measurement of serum levels of macrophage inhibitory cytokine 1 combined with prostate-specific antigen improves prostate cancer diagnosis. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 12: 89-96. PMID 16397029 DOI: 10.1158/1078-0432.Ccr-05-1331  0.391
2006 Stephan C, Xu C, Brown DA, Breit SN, Michael A, Nakamura T, Diamandis EP, Meyer H, Cammann H, Jung K. Three new serum markers for prostate cancer detection within a percent free PSA-based artificial neural network. The Prostate. 66: 651-9. PMID 16388506 DOI: 10.1002/Pros.20381  0.361
2006 Petraki CD, Gregorakis AK, Vaslamatzis MM, Papanastasiou PA, Yousef GM, Levesque MA, Diamandis EP. Prognostic implications of the immunohistochemical expression of human kallikreins 5, 6, 10 and 11 in renal cell carcinoma. Tumour Biology : the Journal of the International Society For Oncodevelopmental Biology and Medicine. 27: 1-7. PMID 16340244 DOI: 10.1159/000090150  0.532
2006 Darling M, Jackson-Boeters L, Daley T, Diamandis E. Human kallikrein 13 expression in salivary gland tumors The International Journal of Biological Markers. 21: 106-110. DOI: 10.5301/Jbm.2008.1948  0.313
2006 Magdolen V, Viktorov P, Holzscheiter L, Arlt M, Soosaipillai A, Talieri M, Diamandis E, Schmitt M, Krüger A, Prezas P. ID: 119 Effects of overexpression of the human tissue kallikrein genes KLK4, 5, 6, and 7 on the malignant phenotype of ovarian cancer cells Journal of Thrombosis and Haemostasis. 4: 71-71. DOI: 10.1111/J.1538-7836.2006.00119.X  0.387
2006 Zhu P, Bowden P, Pendrak V, Thiele H, Zhang D, Siu M, Diamandis EP, Marshall J. Comparison of protein expression lists from mass spectrometry of human blood fluids using exact peptide sequences versus BLAST Clinical Proteomics. 2: 185-203. DOI: 10.1007/Bf02752500  0.308
2005 Darling MR, Jackson-Boeters L, Daley TD, Diamandis EP. Human kallikrein 6 expression in salivary gland tumors. The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. 54: 337-42. PMID 16286664 DOI: 10.1369/Jhc.5A6803.2005  0.311
2005 Yousef GM, Ejeckam GC, Best LM, Diamandis EP. Collecting duct carcinoma associated with oncocytoma. International Braz J Urol : Official Journal of the Brazilian Society of Urology. 31: 465-7; discussion 46. PMID 16255793 DOI: 10.1590/S1677-55382005000500008  0.489
2005 Sidiropoulos M, Pampalakis G, Sotiropoulou G, Katsaros D, Diamandis EP. Downregulation of human kallikrein 10 (KLK10/NES1) by CpG island hypermethylation in breast, ovarian and prostate cancers. Tumour Biology : the Journal of the International Society For Oncodevelopmental Biology and Medicine. 26: 324-36. PMID 16254462 DOI: 10.1159/000089290  0.42
2005 Stephan C, Jung K, Soosaipillai A, Yousef GM, Cammann H, Meyer H, Xu C, Diamandis EP. Clinical utility of human glandular kallikrein 2 within a neural network for prostate cancer detection. Bju International. 96: 521-7. PMID 16104903 DOI: 10.1111/J.1464-410X.2005.05677.X  0.56
2005 Yousef GM, White NM, Michael IP, Cho JC, Robb JD, Kurlender L, Khan S, Diamandis EP. Identification of new splice variants and differential expression of the human kallikrein 10 gene, a candidate cancer biomarker. Tumour Biology : the Journal of the International Society For Oncodevelopmental Biology and Medicine. 26: 227-35. PMID 16103744 DOI: 10.1159/000087377  0.61
2005 Komatsu N, Saijoh K, Toyama T, Ohka R, Otsuki N, Hussack G, Takehara K, Diamandis EP. Multiple tissue kallikrein mRNA and protein expression in normal skin and skin diseases British Journal of Dermatology. 153: 274-281. PMID 16086736 DOI: 10.1111/J.1365-2133.2005.06754.X  0.305
2005 Rosen DG, Wang L, Atkinson JN, Yu Y, Lu KH, Diamandis EP, Hellstrom I, Mok SC, Liu J, Bast RC. Potential markers that complement expression of CA125 in epithelial ovarian cancer. Gynecologic Oncology. 99: 267-77. PMID 16061277 DOI: 10.1016/J.Ygyno.2005.06.040  0.351
2005 Yousef GM, Obiezu CV, Luo LY, Magklara A, Borgoño CA, Kishi T, Memari N, Michael lP, Sidiropoulos M, Kurlender L, Economopolou K, Kapadia C, Komatsu N, Petraki C, Elliott M, ... ... Diamandis EP, et al. Human tissue kallikreins: from gene structure to function and clinical applications. Advances in Clinical Chemistry. 39: 11-79. PMID 16013667 DOI: 10.1016/S0065-2423(04)39002-5  0.609
2005 Obiezu CV, Shan SJ, Soosaipillai A, Luo LY, Grass L, Sotiropoulou G, Petraki CD, Papanastasiou PA, Levesque MA, Diamandis EP. Human kallikrein 4: quantitative study in tissues and evidence for its secretion into biological fluids. Clinical Chemistry. 51: 1432-42. PMID 15961548 DOI: 10.1373/Clinchem.2005.049692  0.357
2005 Obiezu CV, Diamandis EP. Human tissue kallikrein gene family: applications in cancer. Cancer Letters. 224: 1-22. PMID 15911097 DOI: 10.1016/J.Canlet.2004.09.024  0.463
2005 Kurlender L, Borgono C, Michael IP, Obiezu C, Elliott MB, Yousef GM, Diamandis EP. A survey of alternative transcripts of human tissue kallikrein genes. Biochimica Et Biophysica Acta. 1755: 1-14. PMID 15878240 DOI: 10.1016/J.Bbcan.2005.02.001  0.544
2005 Santin AD, Diamandis EP, Bellone S, Soosaipillai A, Cane S, Palmieri M, Burnett A, Roman JJ, Pecorelli S. Human kallikrein 6: a new potential serum biomarker for uterine serous papillary cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 11: 3320-5. PMID 15867230 DOI: 10.1158/1078-0432.Ccr-04-2528  0.375
2005 Felber LM, Borgoño CA, Cloutier SM, Kündig C, Kishi T, Ribeiro Chagas J, Jichlinski P, Gygi CM, Leisinger HJ, Diamandis EP, Deperthes D. Enzymatic profiling of human kallikrein 14 using phage-display substrate technology. Biological Chemistry. 386: 291-8. PMID 15843175 DOI: 10.1515/Bc.2005.035  0.404
2005 Michael IP, Sotiropoulou G, Pampalakis G, Magklara A, Ghosh M, Wasney G, Diamandis EP. Biochemical and enzymatic characterization of human kallikrein 5 (hK5), a novel serine protease potentially involved in cancer progression. The Journal of Biological Chemistry. 280: 14628-35. PMID 15713679 DOI: 10.1074/Jbc.M408132200  0.325
2005 Michael IP, Kurlender L, Memari N, Yousef GM, Du D, Grass L, Stephan C, Jung K, Diamandis EP. Intron retention: a common splicing event within the human kallikrein gene family. Clinical Chemistry. 51: 506-15. PMID 15650036 DOI: 10.1373/Clinchem.2004.042341  0.549
2005 Ghosh MC, Grass L, Soosaipillai A, Sotiropoulou G, Diamandis EP. Human kallikrein 6 degrades extracellular matrix proteins and may enhance the metastatic potential of tumour cells. Tumour Biology : the Journal of the International Society For Oncodevelopmental Biology and Medicine. 25: 193-9. PMID 15557757 DOI: 10.1159/000081102  0.349
2005 Diamandis EP, Borgoño CA, Scorilas A, Harbeck N, Dorn J, Schmitt M. Human kallikrein 11: an indicator of favorable prognosis in ovarian cancer patients. Clinical Biochemistry. 37: 823-9. PMID 15329323 DOI: 10.1016/J.Clinbiochem.2004.04.009  0.438
2005 Hoffman BR, Diamandis EP. Recent advances in cancer biomarkers. Clinical Biochemistry. 37: 503-4. PMID 15234230 DOI: 10.1016/J.Clinbiochem.2004.05.021  0.376
2005 Schmalfeldt B, Kates R, Dorn J, Scorilas A, Grass L, Soosaipillai A, Diamandis E, Kiechle M, Schmitt M, Harbeck N. Impact of proteolytic factors on surgical success and survival in ovarian cancer Journal of Clinical Oncology. 23: 5068-5068. DOI: 10.1200/Jco.2005.23.16_Suppl.5068  0.365
2004 Yousef GM, Borgoño CA, White NM, Robb JD, Michael IP, Oikonomopoulou K, Khan S, Diamandis EP. In silico analysis of the human kallikrein gene 6. Tumour Biology : the Journal of the International Society For Oncodevelopmental Biology and Medicine. 25: 282-9. PMID 15627893 DOI: 10.1159/000081393  0.588
2004 Yousef GM, White NM, Kurlender L, Michael I, Memari N, Robb JD, Katsaros D, Stephan C, Jung K, Diamandis EP. The kallikrein gene 5 splice variant 2 is a new biomarker for breast and ovarian cancer. Tumour Biology : the Journal of the International Society For Oncodevelopmental Biology and Medicine. 25: 221-7. PMID 15627884 DOI: 10.1159/000081384  0.602
2004 Borgoño CA, Diamandis EP. The emerging roles of human tissue kallikreins in cancer. Nature Reviews. Cancer. 4: 876-90. PMID 15516960 DOI: 10.1038/Nrc1474  0.405
2004 Yousef GM, Borgono CA, Michael IP, Diamandis EP. Cloning of a kallikrein pseudogene. Clinical Biochemistry. 37: 961-7. PMID 15498522 DOI: 10.1016/J.Clinbiochem.2004.07.012  0.56
2004 Kapadia C, Ghosh MC, Grass L, Diamandis EP. Human kallikrein 13 involvement in extracellular matrix degradation. Biochemical and Biophysical Research Communications. 323: 1084-90. PMID 15381110 DOI: 10.1016/J.Bbrc.2004.08.206  0.389
2004 Kurlender L, Yousef GM, Memari N, Robb JD, Michael IP, Borgoño C, Katsaros D, Stephan C, Jung K, Diamandis EP. Differential expression of a human kallikrein 5 (KLK5) splice variant in ovarian and prostate cancer. Tumour Biology : the Journal of the International Society For Oncodevelopmental Biology and Medicine. 25: 149-56. PMID 15361712 DOI: 10.1159/000079147  0.613
2004 Yousef GM, Borgoño CA, Michael IP, Davidian C, Stephan C, Jung K, Diamandis EP. Molecular cloning of a new gene which is differentially expressed in breast and prostate cancers. Tumour Biology : the Journal of the International Society For Oncodevelopmental Biology and Medicine. 25: 122-33. PMID 15361709 DOI: 10.1159/000079144  0.571
2004 Diamandis EP. Proteomic patterns to identify ovarian cancer: 3 years on. Expert Review of Molecular Diagnostics. 4: 575-7. PMID 15347249 DOI: 10.1586/14737159.4.5.575  0.342
2004 Pampalakis G, Kurlender L, Diamandis EP, Sotiropoulou G. Cloning and characterization of novel isoforms of the human kallikrein 6 gene. Biochemical and Biophysical Research Communications. 320: 54-61. PMID 15207701 DOI: 10.1016/J.Bbrc.2004.04.205  0.349
2004 Borgoño CA, Michael IP, Diamandis EP. Human tissue kallikreins: physiologic roles and applications in cancer. Molecular Cancer Research : McR. 2: 257-80. PMID 15192120  0.313
2004 Diamandis EP. How are we going to discover new cancer biomarkers? A proteomic approach for bladder cancer. Clinical Chemistry. 50: 793-5. PMID 15105344 DOI: 10.1373/Clinchem.2004.032177  0.419
2004 Yousef GM, Elliott MB, Kopolovic AD, Serry E, Diamandis EP. Sequence and evolutionary analysis of the human trypsin subfamily of serine peptidases. Biochimica Et Biophysica Acta. 1698: 77-86. PMID 15063317 DOI: 10.1016/J.Bbapap.2003.10.008  0.512
2004 Antoniou A, Papanastasiou P, Stephanidis A, Diamandis E, Androulakakis PA. Assessment of serum prostate specific antigen in childhood. Bju International. 93: 838-40. PMID 15050001 DOI: 10.1111/J.1464-410X.2003.04740.X  0.323
2004 Sauter ER, Klein G, Wagner-Mann C, Diamandis EP. Prostate-specific antigen expression in nipple aspirate fluid is associated with advanced breast cancer. Cancer Detection and Prevention. 28: 27-31. PMID 15041074 DOI: 10.1016/J.Cdp.2003.11.003  0.375
2004 Yousef GM, Borgoño CA, Popalis C, Yacoub GM, Polymeris ME, Soosaipillai A, Diamandis EP. In-silico analysis of kallikrein gene expression in pancreatic and colon cancers. Anticancer Research. 24: 43-51. PMID 15015574  0.545
2004 Diamandis EP, Yousef GM, Olsson AY. An update on human and mouse glandular kallikreins. Clinical Biochemistry. 37: 258-60. PMID 15003726 DOI: 10.1016/J.Clinbiochem.2003.12.013  0.509
2004 Diamandis EP. Analysis of serum proteomic patterns for early cancer diagnosis: drawing attention to potential problems. Journal of the National Cancer Institute. 96: 353-6. PMID 14996856 DOI: 10.1093/Jnci/Djh056  0.442
2004 Diamandis EP. Mass spectrometry as a diagnostic and a cancer biomarker discovery tool: opportunities and potential limitations. Molecular & Cellular Proteomics : McP. 3: 367-78. PMID 14990683 DOI: 10.1074/Mcp.R400007-Mcp200  0.408
2004 Scorilas A, Borgoño CA, Harbeck N, Dorn J, Schmalfeldt B, Schmitt M, Diamandis EP. Human kallikrein 13 protein in ovarian cancer cytosols: a new favorable prognostic marker. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 22: 678-85. PMID 14966091 DOI: 10.1200/Jco.2004.05.144  0.436
2004 Diamandis EP. Re: diagnostic potential of serum proteomic patterns in prostate cancer. The Journal of Urology. 171: 1244-5; author reply. PMID 14767317 DOI: 10.1097/01.Ju.0000112784.51142.Bd  0.393
2004 Yousef GM, Yacoub GM, Polymeris ME, Popalis C, Soosaipillai A, Diamandis EP. Kallikrein gene downregulation in breast cancer British Journal of Cancer. 90: 167-172. PMID 14710225 DOI: 10.1038/sj.bjc.6601451  0.519
2004 Sauter ER, Lininger J, Magklara A, Hewett JE, Diamandis EP. Association of kallikrein expression in nipple aspirate fluid with breast cancer risk. International Journal of Cancer. Journal International Du Cancer. 108: 588-91. PMID 14696124 DOI: 10.1002/Ijc.11607  0.38
2004 Talieri M, Diamandis EP, Gourgiotis D, Mathioudaki K, Scorilas A. Expression analysis of the human kallikrein 7 (KLK7) in breast tumors: a new potential biomarker for prognosis of breast carcinoma. Thrombosis and Haemostasis. 91: 180-6. PMID 14691584 DOI: 10.1160/Th03-05-0261  0.376
2004 Kapadia C, Yousef GM, Mellati AA, Magklara A, Wasney GA, Diamandis EP. Complex formation between human kallikrein 13 and serum protease inhibitors. Clinica Chimica Acta; International Journal of Clinical Chemistry. 339: 157-67. PMID 14687906 DOI: 10.1016/J.Cccn.2003.10.009  0.518
2004 Stephan C, Yousef GM, Scorilas A, Jung K, Jung M, Kristiansen G, Hauptmann S, Kishi T, Nakamura T, Loening SA, Diamandis EP. Hepsin is highly over expressed in and a new candidate for a prognostic indicator in prostate cancer. The Journal of Urology. 171: 187-91. PMID 14665873 DOI: 10.1097/01.Ju.0000101622.74236.94  0.594
2004 Yousef GM, White NMA, Golmakani N, Louhimo J, Song L, Yan W, Deng M, Song S, Zhang J, Zhao T, Omidfar K, Rasaee MJ, Modjtahedi H, Forouzandeh M, Taghikhani M, ... ... Diamandis EP, et al. Contents Vol. 25, 2004 Tumor Biology. 25: 341-342. DOI: 10.1159/000083075  0.437
2004 Yousef GM, White NMA, Golmakani N, Louhimo J, Song L, Yan W, Deng M, Song S, Zhang J, Zhao T, Omidfar K, Rasaee MJ, Modjtahedi H, Forouzandeh M, Taghikhani M, ... ... Diamandis EP, et al. Subject Index Vol. 25, 2004 Tumor Biology. 25: 339-340. DOI: 10.1159/000083074  0.446
2003 Diamandis EP, Borgoño CA, Scorilas A, Yousef GM, Harbeck N, Dorn J, Schmalfeldt B, Schmitt M. Immunofluorometric quantification of human kallikrein 5 expression in ovarian cancer cytosols and its association with unfavorable patient prognosis. Tumour Biology : the Journal of the International Society For Oncodevelopmental Biology and Medicine. 24: 299-309. PMID 15004490 DOI: 10.1159/000076462  0.569
2003 Borgoño CA, Grass L, Soosaipillai A, Yousef GM, Petraki CD, Howarth DH, Fracchioli S, Katsaros D, Diamandis EP. Human kallikrein 14: a new potential biomarker for ovarian and breast cancer. Cancer Research. 63: 9032-41. PMID 14695222  0.578
2003 Luo LY, Grass L, Diamandis EP. Steroid hormone regulation of the human kallikrein 10 (KLK10) gene in cancer cell lines and functional characterization of the KLK10 gene promoter. Clinica Chimica Acta; International Journal of Clinical Chemistry. 337: 115-26. PMID 14568187 DOI: 10.1016/J.Cccn.2003.07.008  0.363
2003 Yousef GM, Diamandis EP. An overview of the kallikrein gene families in humans and other species: emerging candidate tumour markers. Clinical Biochemistry. 36: 443-52. PMID 12951170 DOI: 10.1016/S0009-9120(03)00055-9  0.561
2003 Yousef GM, Scorilas A, Katsaros D, Fracchioli S, Iskander L, Borgono C, Rigault de la Longrais IA, Puopolo M, Massobrio M, Diamandis EP. Prognostic value of the human kallikrein gene 15 expression in ovarian cancer. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 21: 3119-26. PMID 12915603 DOI: 10.1200/Jco.2003.09.111  0.604
2003 Yousef GM, Kapadia C, Polymeris ME, Borgono C, Hutchinson S, Wasney GA, Soosaipillai A, Diamandis EP. The human kallikrein protein 5 (hK5) is enzymatically active, glycosylated and forms complexes with two protease inhibitors in ovarian cancer fluids. Biochimica Et Biophysica Acta. 1628: 88-96. PMID 12890555 DOI: 10.1016/S0167-4781(03)00116-7  0.563
2003 Diamandis EP. Point: Proteomic patterns in biological fluids: do they represent the future of cancer diagnostics? Clinical Chemistry. 49: 1272-5. PMID 12881441 DOI: 10.1373/49.8.1272  0.421
2003 Magklara A, Mellati AA, Wasney GA, Little SP, Sotiropoulou G, Becker GW, Diamandis EP. Characterization of the enzymatic activity of human kallikrein 6: Autoactivation, substrate specificity, and regulation by inhibitors. Biochemical and Biophysical Research Communications. 307: 948-55. PMID 12878203 DOI: 10.1016/S0006-291X(03)01271-3  0.369
2003 Yousef GM, Diamandis EP. Tissue kallikreins: new players in normal and abnormal cell growth? Thrombosis and Haemostasis. 90: 7-16. PMID 12876620 DOI: 10.1267/THRO03010007  0.534
2003 Yousef GM, Polymeris ME, Grass L, Soosaipillai A, Chan PC, Scorilas A, Borgoño C, Harbeck N, Schmalfeldt B, Dorn J, Schmitt M, Diamandis EP. Human kallikrein 5: a potential novel serum biomarker for breast and ovarian cancer. Cancer Research. 63: 3958-65. PMID 12873991  0.562
2003 Yousef GM, Stephan C, Scorilas A, Ellatif MA, Jung K, Kristiansen G, Jung M, Polymeris ME, Diamandis EP. Differential expression of the human kallikrein gene 14 (KLK14) in normal and cancerous prostatic tissues. The Prostate. 56: 287-92. PMID 12858357 DOI: 10.1002/Pros.10263  0.616
2003 Borgoño CA, Fracchioli S, Yousef GM, Rigault de la Longrais IA, Luo LY, Soosaipillai A, Puopolo M, Grass L, Scorilas A, Diamandis EP, Katsaros D. Favorable prognostic value of tissue human kallikrein 11 (hK11) in patients with ovarian carcinoma. International Journal of Cancer. Journal International Du Cancer. 106: 605-10. PMID 12845660 DOI: 10.1002/Ijc.11296  0.585
2003 Nam RK, Zhang WW, Trachtenberg J, Diamandis E, Toi A, Emami M, Ho M, Sweet J, Evans A, Jewett MA, Narod SA. Single nucleotide polymorphism of the human kallikrein-2 gene highly correlates with serum human kallikrein-2 levels and in combination enhances prostate cancer detection. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 21: 2312-9. PMID 12805332 DOI: 10.1200/Jco.2003.11.007  0.392
2003 Scorilas A, Chiang PM, Katsaros D, Yousef GM, Diamandis EP. Molecular characterization of a new gene, CEAL1, encoding for a carcinoembryonic antigen-like protein with a highly conserved domain of eukaryotic translation initiation factors. Gene. 310: 79-89. PMID 12801635 DOI: 10.1016/S0378-1119(03)00499-2  0.594
2003 Kollara A, Diamandis EP, Brown TJ. Secretion of endogenous kallikreins 2 and 3 by androgen receptor-transfected PC-3 prostate cancer cells Journal of Steroid Biochemistry and Molecular Biology. 84: 493-502. PMID 12767274 DOI: 10.1016/S0960-0760(03)00069-4  0.317
2003 Luo LY, Yousef G, Diamandis EP. Human tissue kallikreins and testicular cancer. Apmis : Acta Pathologica, Microbiologica, Et Immunologica Scandinavica. 111: 225-32; discussion 2. PMID 12752266 DOI: 10.1034/J.1600-0463.2003.11101261.X  0.614
2003 Nakamura T, Stephan C, Scorilas A, Yousef GM, Jung K, Diamandis EP. Quantitative analysis of hippostasin/KLK11 gene expression in cancerous and noncancerous prostatic tissues. Urology. 61: 1042-6. PMID 12736044 DOI: 10.1016/S0090-4295(02)02443-3  0.585
2003 Yousef GM, Kopolovic AD, Elliott MB, Diamandis EP. Genomic overview of serine proteases. Biochemical and Biophysical Research Communications. 305: 28-36. PMID 12732192 DOI: 10.1016/S0006-291X(03)00638-7  0.495
2003 Yousef GM, Polymeris ME, Yacoub GM, Scorilas A, Soosaipillai A, Popalis C, Fracchioli S, Katsaros D, Diamandis EP. Parallel overexpression of seven kallikrein genes in ovarian cancer. Cancer Research. 63: 2223-7. PMID 12727843  0.565
2003 Sotiropoulou G, Rogakos V, Tsetsenis T, Pampalakis G, Zafiropoulos N, Simillides G, Yiotakis A, Diamandis EP. Emerging interest in the kallikrein gene family for understanding and diagnosing cancer. Oncology Research. 13: 381-91. PMID 12725528 DOI: 10.3727/096504003108748393  0.414
2003 Yousef GM, Scorilas A, Nakamura T, Ellatif MA, Ponzone R, Biglia N, Maggiorotto F, Roagna R, Sismondi P, Diamandis EP. The prognostic value of the human kallikrein gene 9 (KLK9) in breast cancer. Breast Cancer Research and Treatment. 78: 149-58. PMID 12725415 DOI: 10.1023/A:1022931403825  0.591
2003 Hutchinson S, Luo LY, Yousef GM, Soosaipillai A, Diamandis EP. Purification of human kallikrein 6 from biological fluids and identification of its complex with alpha(1)-antichymotrypsin. Clinical Chemistry. 49: 746-51. PMID 12709365 DOI: 10.1373/49.5.746  0.551
2003 Nakamura T, Scorilas A, Stephan C, Yousef GM, Kristiansen G, Jung K, Diamandis EP. Quantitative analysis of macrophage inhibitory cytokine-1 (MIC-1) gene expression in human prostatic tissues British Journal of Cancer. 88: 1101-1104. PMID 12671711 DOI: 10.1038/Sj.Bjc.6600869  0.603
2003 Yousef GM, Fracchioli S, Scorilas A, Borgoño CA, Iskander L, Puopolo M, Massobrio M, Diamandis EP, Katsaros D. Steroid hormone regulation and prognostic value of the human kallikrein gene 14 in ovarian cancer. American Journal of Clinical Pathology. 119: 346-55. PMID 12645335 DOI: 10.1309/0Ua57Mnayv0Mce9U  0.596
2003 Diamandis EP. Re: Serum proteomic patterns for detection of prostate cancer. Journal of the National Cancer Institute. 95: 489-90; author reply. PMID 12644546 DOI: 10.1093/Jnci/95.6.489  0.386
2003 Petraki CD, Karavana VN, Diamandis EP. Human kallikrein 13 expression in normal tissues: an immunohistochemical study. The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. 51: 493-501. PMID 12642628 DOI: 10.1177/002215540305100411  0.327
2003 Diamandis EP, Scorilas A, Fracchioli S, Van Gramberen M, De Bruijn H, Henrik A, Soosaipillai A, Grass L, Yousef GM, Stenman UH, Massobrio M, Van Der Zee AGJ, Vergote I, Katsaros D. Human kallikrein 6 (hK6): A new potential serum biomarker for diagnosis and prognosis of ovarian carcinoma Journal of Clinical Oncology. 21: 1035-1043. PMID 12637468 DOI: 10.1200/Jco.2003.02.022  0.549
2003 Kyriakopoulou LG, Yousef GM, Scorilas A, Katsaros D, Massobrio M, Fracchioli S, Diamandis EP. Prognostic value of quantitatively assessed KLK7 expression in ovarian cancer Clinical Biochemistry. 36: 135-143. PMID 12633763 DOI: 10.1016/S0009-9120(02)00446-0  0.595
2003 Yousef GM, Kishi T, Diamandis EP. Role of kallikrein enzymes in the central nervous system Clinica Chimica Acta. 329: 1-8. PMID 12589961 DOI: 10.1016/S0009-8981(03)00004-4  0.535
2003 Scorilas A, Plebani M, Mazza S, Basso D, Soosaipillai AR, Katsaros N, Pagano F, Diamandis EP. Serum human glandular kallikrein (hK2) and insulin-like growth factor 1 (IGF-1) improve the discrimination between prostate cancer and benign prostatic hyperplasia in combination with total and %free PSA. The Prostate. 54: 220-9. PMID 12518327 DOI: 10.1002/Pros.10186  0.365
2003 Kishi T, Grass L, Soosaipillai A, Shimizu-Okabe C, Diamandis EP. Human kallikrein 8: immunoassay development and identification in tissue extracts and biological fluids. Clinical Chemistry. 49: 87-96. PMID 12507964 DOI: 10.1373/49.1.87  0.305
2003 Kapadia C, Chang A, Sotiropoulou G, Yousef GM, Grass L, Soosaipillai A, Xing X, Howarth DHC, Diamandis EP. Human kallikrein 13: Production and purification of recombinant protein and monoclonal and polyclonal antibodies, and development of a sensitive and specific immunofluorometric assay Clinical Chemistry. 49: 77-86. PMID 12507963 DOI: 10.1373/49.1.77  0.614
2003 Stephan C, Yousef GM, Scorilas A, Jung K, Jung M, Kristiansen G, Hauptmann S, Bharaj BS, Nakamura T, Loening SA, Diamandis EP. Quantitative analysis of kallikrein 15 gene expression in prostate tissue Journal of Urology. 169: 361-364. PMID 12478190  0.561
2003 Yousef GM, Diamandis EP. Human kallikreins: Common structural features, sequence analysis and evolution Current Genomics. 4: 147-165. DOI: 10.2174/1389202033350074  0.565
2003 Okano K, Fukui M, Suehiro Y, Hamanaka Y, Imai K, Hinoda Y, Yousef GM, Harbeck N, Dorn J, Schmalfeldt B, Schmitt M, Yang H, Liu VWS, Tsang PCK, Yip AMW, ... ... Diamandis EP, et al. Contents Vol. 24, 2003 Tumor Biology. 24: 329-330. DOI: 10.1159/000077138  0.437
2003 Okano K, Fukui M, Suehiro Y, Hamanaka Y, Imai K, Hinoda Y, Yousef GM, Harbeck N, Dorn J, Schmalfeldt B, Schmitt M, Yang H, Liu VWS, Tsang PCK, Yip AMW, ... ... Diamandis EP, et al. Subject Index Vol. 24, 2003 Tumor Biology. 24: 327-328. DOI: 10.1159/000077137  0.446
2003 Katsaros D, Fracchioli S, de la Longrais IAR, Puopolo M, Yousef GM, Vergote I, van der Zee AG, Diamandis E. HUMAN KALLIKREINS (HKS) AS NOVEL SERUM BIOMARKERS IN OVARIAN CANCER International Journal of Gynecologic Cancer. 13: 19.2-20. DOI: 10.1136/Ijgc-00009577-200303001-00066  0.581
2003 Fracchioli S, Yousef GM, de la Longrais IAR, Puopolo M, Richiardi G, Danese S, Diamandis E, Katsaros D. HUMAN KALLIKREIN GENE 15 (KLK15) EXPRESSION International Journal of Gynecologic Cancer. 13: 19.1-19. DOI: 10.1136/Ijgc-00009577-200303001-00065  0.518
2003 Yousef G, Diamandis E. Tissue kallikreins: new players in normal and abnormal cell growth? Thrombosis and Haemostasis. 90: 7-16. DOI: 10.1055/S-0037-1613593  0.583
2003 Talieri M, Diamandis E, Katsaros N, Gourgiotis D, Scorilas A. Expression of BCL2L12, a new member of apoptosis-related genes, in breast tumors Thrombosis and Haemostasis. 89: 1081-1088. DOI: 10.1055/S-0037-1613411  0.367
2003 STEPHAN C, YOUSEF GM, SCORILAS A, JUNG K, JUNG M, KRISTIANSEN G, HAUPTMANN S, BHARAJ BS, NAKAMURA T, LOENING SA, DIAMANDIS EP. Quantitative Analysis of Kallikrein 15 Gene Expression in Prostate Tissue Journal of Urology. 169: 361-364. DOI: 10.1016/S0022-5347(05)64127-4  0.605
2002 Yousef GM, Scorilas A, Magklara A, Memari N, Ponzone R, Sismondi P, Biglia N, Abd Ellatif M, Diamandis EP. The androgen-regulated gene human kallikrein 15 (KLK15) is an independent and favourable prognostic marker for breast cancer British Journal of Cancer. 87: 1294-1300. PMID 12439720 DOI: 10.1038/Sj.Bjc.6600590  0.607
2002 Yousef GM, Borgoño CA, Scorilas A, Ponzone R, Biglia N, Iskander L, Polymeris ME, Roagna R, Sismondi P, Diamandis EP. Quantitative analysis of human kallikrein gene 14 expression in breast tumours indicates association with poor prognosis British Journal of Cancer. 87: 1287-1293. PMID 12439719 DOI: 10.1038/sj.bjc.6600623  0.538
2002 Yousef GM, Diamandis EP. Human tissue kallikreins: A new enzymatic cascade pathway? Biological Chemistry. 383: 1045-1057. PMID 12437087 DOI: 10.1515/Bc.2002.113  0.582
2002 Yousef GM, Obiezu CV, Jung K, Stephan C, Scorilas A, Diamandis EP. Differential expression of kallikrein gene 5 in cancerous and normal testicular tissues Urology. 60: 714-718. PMID 12385949 DOI: 10.1016/S0090-4295(02)01811-3  0.583
2002 Rosenberg Zand RS, Jenkins DJ, Diamandis EP. Flavonoids and steroid hormone-dependent cancers. Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences. 777: 219-32. PMID 12270215 DOI: 10.1016/S1570-0232(02)00213-1  0.371
2002 Hoffman BR, Katsaros D, Scorilas A, Diamandis P, Fracchioli S, Rigault de la Longrais IA, Colgan T, Puopolo M, Giardina G, Massobrio M, Diamandis EP. Immunofluorometric quantitation and histochemical localisation of kallikrein 6 protein in ovarian cancer tissue: a new independent unfavourable prognostic biomarker. British Journal of Cancer. 87: 763-71. PMID 12232761 DOI: 10.1038/Sj.Bjc.6600533  0.349
2002 Yousef GM, Diamandis EP. Expanded human tissue kallikrein family - A novel panel of cancer biomarkers Tumor Biology. 23: 185-192. PMID 12218299 DOI: 10.1159/000064027  0.639
2002 Sauter ER, Welch T, Magklara A, Klein G, Diamandis EP. Ethnic variation in kallikrein expression in nipple aspirate fluid. International Journal of Cancer. 100: 678-82. PMID 12209605 DOI: 10.1002/Ijc.10556  0.357
2002 Petraki CD, Karavana VN, Luo LY, Diamandis EP. Human kallikrein 10 expression in normal tissues by immunohistochemistry. The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. 50: 1247-61. PMID 12185203 DOI: 10.1177/002215540205000912  0.37
2002 Yousef GM, Scorilas A, Kyriakopoulou LG, Rendl L, Diamandis M, Ponzone R, Biglia N, Giai M, Roagna R, Sismondi P, Diamandis EP. Human kallikrein gene 5 (KLK5) expression by quantitative PCR: An independent indicator of poor prognosis in breast cancer Clinical Chemistry. 48: 1241-1250. PMID 12142380  0.528
2002 Obiezu CV, Soosaipillai A, Jung K, Stephan C, Scorilas A, Howarth DH, Diamandis EP. Detection of human kallikrein 4 in healthy and cancerous prostatic tissues by immunofluorometry and immunohistochemistry. Clinical Chemistry. 48: 1232-40. PMID 12142379  0.322
2002 Diamandis EP, Yousef GM. Human tissue kallikreins: A family of new cancer biomarkers Clinical Chemistry. 48: 1198-1205. PMID 12142373  0.592
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