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Major Gooyit - Publications

Affiliations: 
Scripps Research Institute, La Jolla, La Jolla, CA, United States 
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24 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Nguyen TT, Wolter WR, Anderson B, Schroeder VA, Gao M, Gooyit M, Suckow MA, Chang M. Limitations of Knockout Mice and Other Tools in Assessment of the Involvement of Matrix Metalloproteinases in Wound Healing and the Means to Overcome Them. Acs Pharmacology & Translational Science. 3: 489-495. PMID 32566914 DOI: 10.1021/acsptsci.9b00109  0.502
2016 Gooyit MD, Miranda PO, Wenthur CJ, Ducime A, Janda KD. Influencing antibody-mediated attenuation of methamphetamine CNS distribution through vaccine linker design. Acs Chemical Neuroscience. PMID 27958709 DOI: 10.1021/Acschemneuro.6B00389  0.63
2016 Marusak C, Bayles I, Ma J, Gooyit M, Gao M, Chang M, Bedogni B. The thiirane-based selective MT1-MMP/MMP2 inhibitor ND-322 reduces melanoma tumor growth and delays metastatic dissemination. Pharmacological Research. PMID 27687955 DOI: 10.1016/J.Phrs.2016.09.033  0.556
2016 Gooyit M, Janda KD. Reprofiled anthelmintics abate hypervirulent stationary-phase Clostridium difficile. Scientific Reports. 6: 33642. PMID 27633064 DOI: 10.1038/Srep33642  0.336
2016 Gooyit MD, Janda KD. Modulation of the Surface-Layer Protein of Clostridium difficile through Cwp84 Inhibition. Acs Infectious Diseases. 2: 465-70. PMID 27626098 DOI: 10.1021/Acsinfecdis.6B00061  0.394
2016 Tsuchikama K, Gooyit M, Harris TL, Zhu J, Globisch D, Kaufmann GF, Janda KD. Glycation Reactivity of a Quorum-Sensing Signaling Molecule. Angewandte Chemie (International Ed. in English). PMID 26890076 DOI: 10.1002/Anie.201511911  0.597
2016 Gooyit M, Peng Z, Mobashery S, Chang M. Chapter 10: Thiirane class of gelatinase inhibitors as a privileged template that crosses the blood-brain barrier Rsc Drug Discovery Series. 2016: 262-286. DOI: 10.1039/9781782622246-00262  0.572
2015 Gooyit M, Harris TL, Tricoche N, Javor S, Lustigman S, Janda KD. Onchocerca volvulus Molting Inhibitors Identified through Scaffold Hopping. Acs Infectious Diseases. 1: 198-202. PMID 27622649 DOI: 10.1021/Acsinfecdis.5B00017  0.434
2015 Gao M, Nguyen TT, Suckow MA, Wolter WR, Gooyit M, Mobashery S, Chang M. Acceleration of diabetic wound healing using a novel protease-anti-protease combination therapy. Proceedings of the National Academy of Sciences of the United States of America. PMID 26598687 DOI: 10.1073/Pnas.1517847112  0.629
2015 Semple BD, Noble-Haeusslein LJ, Gooyit M, Tercovich KG, Peng Z, Nguyen TT, Schroeder VA, Suckow MA, Chang M, Raber J, Trivedi A. Early Gelatinase Activity Is Not a Determinant of Long-Term Recovery after Traumatic Brain Injury in the Immature Mouse. Plos One. 10: e0143386. PMID 26588471 DOI: 10.1371/Journal.Pone.0143386  0.55
2015 Lee M, Chen Z, Tomlinson BN, Gooyit M, Hesek D, Juarez MR, Nizam R, Boggess B, Lastochkin E, Schroeder VA, Wolter WR, Suckow MA, Cui J, Mobashery S, Gu Z, et al. Water-soluble MMP-9 inhibitor reduces lesion volume after severe traumatic brain injury. Acs Chemical Neuroscience. PMID 26241578 DOI: 10.1021/Acschemneuro.5B00140  0.665
2015 Zhu J, Cai X, Harris TL, Gooyit M, Wood M, Lardy M, Janda KD. Disarming Pseudomonas aeruginosa virulence factor LasB by leveraging a Caenorhabditis elegans infection model. Chemistry & Biology. 22: 483-91. PMID 25892201 DOI: 10.1016/J.Chembiol.2015.03.012  0.4
2015 Gooyit M, Tricoche N, Javor S, Lustigman S, Janda KD. Exploiting the Polypharmacology of ß-Carbolines to Disrupt O. volvulus Molting. Acs Medicinal Chemistry Letters. 6: 339-43. PMID 25815157 DOI: 10.1021/Ml500516R  0.399
2015 Gao M, Nguyen TT, Suckow MA, Wolter WR, Gooyit M, Mobashery S, Chang M. Acceleration of diabetic wound healing using a novel proteaseanti-protease combination therapy Proceedings of the National Academy of Sciences of the United States of America. 112: 15226-15231. DOI: 10.1073/pnas.1517847112/-/DCSupplemental  0.532
2015 Pippione AC, Dosio F, Ducime A, Federico A, Martina K, Sainas S, Frølund B, Gooyit M, Janda KD, Boschi D, Lolli ML. Substituted 4-hydroxy-1,2,3-triazoles: synthesis, characterization and first drug design applications through bioisosteric modulation and scaffold hopping approaches Medchemcomm. 6: 1285-1292. DOI: 10.1039/C5Md00182J  0.382
2015 Gooyit M, Harris TL, Tricoche N, Javor S, Lustigman S, Janda KD. Onchocerca volvulus Molting Inhibitors Identified through Scaffold Hopping Acs Infectious Diseases. 1: 198-202. DOI: 10.1021/acsinfecdis.5b00017  0.426
2014 Gooyit M, Tricoche N, Lustigman S, Janda KD. Dual protonophore-chitinase inhibitors dramatically affect O. volvulus molting. Journal of Medicinal Chemistry. 57: 5792-9. PMID 24918716 DOI: 10.1021/Jm5006435  0.437
2014 Gooyit M, Peng Z, Wolter WR, Pi H, Ding D, Hesek D, Lee M, Boggess B, Champion MM, Suckow MA, Mobashery S, Chang M. A chemical biological strategy to facilitate diabetic wound healing. Acs Chemical Biology. 9: 105-10. PMID 24053680 DOI: 10.1021/Cb4005468  0.638
2013 Hadass O, Tomlinson BN, Gooyit M, Chen S, Purdy JJ, Walker JM, Zhang C, Giritharan AB, Purnell W, Robinson CR, Shin D, Schroeder VA, Suckow MA, Simonyi A, Sun GY, et al. Selective inhibition of matrix metalloproteinase-9 attenuates secondary damage resulting from severe traumatic brain injury. Plos One. 8: e76904. PMID 24194849 DOI: 10.1371/Journal.Pone.0076904  0.641
2013 Gooyit M, Song W, Mahasenan KV, Lichtenwalter K, Suckow MA, Schroeder VA, Wolter WR, Mobashery S, Chang M. O-phenyl carbamate and phenyl urea thiiranes as selective matrix metalloproteinase-2 inhibitors that cross the blood-brain barrier. Journal of Medicinal Chemistry. 56: 8139-50. PMID 24028490 DOI: 10.1021/Jm401217D  0.655
2013 Song W, Peng Z, Gooyit M, Suckow MA, Schroeder VA, Wolter WR, Lee M, Ikejiri M, Cui J, Gu Z, Chang M. Water-soluble mmp-9 inhibitor prodrug generates active metabolites that cross the blood-brain barrier. Acs Chemical Neuroscience. 4: 1168-73. PMID 23687970 DOI: 10.1021/Cn400077D  0.559
2012 Gooyit M, Suckow MA, Schroeder VA, Wolter WR, Mobashery S, Chang M. Selective gelatinase inhibitor neuroprotective agents cross the blood-brain barrier. Acs Chemical Neuroscience. 3: 730-6. PMID 23077716 DOI: 10.1021/Cn300062W  0.64
2011 Gooyit M, Lee M, Schroeder VA, Ikejiri M, Suckow MA, Mobashery S, Chang M. Selective water-soluble gelatinase inhibitor prodrugs. Journal of Medicinal Chemistry. 54: 6676-90. PMID 21866961 DOI: 10.1021/Jm200566E  0.598
2009 Gooyit M, Lee M, Hesek D, Boggess B, Oliver AG, Fridman R, Mobashery S, Chang M. Synthesis, kinetic characterization and metabolism of diastereomeric 2-(1-(4-phenoxyphenylsulfonyl)ethyl)thiiranes as potent gelatinase and MT1-MMP inhibitors. Chemical Biology & Drug Design. 74: 535-46. PMID 19824893 DOI: 10.1111/J.1747-0285.2009.00898.X  0.645
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