| Year |
Citation |
Score |
| 2018 |
Sadeghi M, Carstens BB, Callaghan BP, Daniel JT, Tae HS, O'Donnell T, Castro J, Brierley SM, Adams DJ, Craik DJ, Clark RJ. Structure-activity studies reveal the molecular basis for GABAB-receptor mediated inhibition of high voltage-activated calcium channels by α-conotoxin Vc1.1. Acs Chemical Biology. PMID 29746088 DOI: 10.1021/Acschembio.8B00190 |
0.785 |
|
| 2014 |
Chhabra S, Belgi A, Bartels P, van Lierop BJ, Robinson SD, Kompella SN, Hung A, Callaghan BP, Adams DJ, Robinson AJ, Norton RS. Dicarba analogues of α-conotoxin RgIA. Structure, stability, and activity at potential pain targets. Journal of Medicinal Chemistry. 57: 9933-44. PMID 25393758 DOI: 10.1021/Jm501126U |
0.759 |
|
| 2013 |
Kompella S, van Lierop B, Robinson S, Belgi A, Callaghan B, Hung A, MacRaild C, Norton R, Robinson A, Adams D. Dicarba modification of α-conotoxin RgIA conferring selectivity towards α9α10 nicotinic acetylcholine receptors Biochemical Pharmacology. 86: 1230. DOI: 10.1016/J.Bcp.2013.08.043 |
0.733 |
|
| 2012 |
Adams DJ, Callaghan B, Berecki G. Analgesic conotoxins: Block and G protein-coupled receptor modulation of N-type (Ca V2.2) calcium channels British Journal of Pharmacology. 166: 486-500. PMID 22091786 DOI: 10.1111/J.1476-5381.2011.01781.X |
0.564 |
|
| 2011 |
Halai R, Callaghan B, Daly NL, Clark RJ, Adams DJ, Craik DJ. Effects of cyclization on stability, structure, and activity of α-conotoxin RgIA at the α9α10 nicotinic acetylcholine receptor and GABA B receptor Journal of Medicinal Chemistry. 54: 6984-6992. PMID 21888386 DOI: 10.1021/Jm201060R |
0.493 |
|
| 2011 |
de Araujo AD, Callaghan B, Nevin ST, Daly NL, Craik DJ, Moretta M, Hopping G, Christie MJ, Adams DJ, Alewood PF. Total synthesis of the analgesic conotoxin MrVIB through selenocysteine-assisted folding. Angewandte Chemie (International Ed. in English). 50: 6527-9. PMID 21630402 DOI: 10.1002/Anie.201101642 |
0.678 |
|
| 2011 |
Safavi-Hemami H, Siero WA, Kuang Z, Williamson NA, Karas JA, Page LR, MacMillan D, Callaghan B, Kompella SN, Adams DJ, Norton RS, Purcell AW. Embryonic toxin expression in the cone snail Conus victoriae: primed to kill or divergent function? The Journal of Biological Chemistry. 286: 22546-57. PMID 21504902 DOI: 10.1074/Jbc.M110.217703 |
0.725 |
|
| 2011 |
Daly NL, Callaghan B, Clark RJ, Nevin ST, Adams DJ, Craik DJ. Structure and activity of α-conotoxin PeIA at nicotinic acetylcholine receptor subtypes and GABAB receptor-coupled N-type calcium channels Journal of Biological Chemistry. 286: 10233-10237. PMID 21252227 DOI: 10.1074/Jbc.M110.196170 |
0.751 |
|
| 2011 |
Klimis H, Adams DJ, Callaghan B, Nevin S, Alewood PF, Vaughan CW, Mozar CA, Christie MJ. A novel mechanism of inhibition of high-voltage activated calcium channels by α-conotoxins contributes to relief of nerve injury-induced neuropathic pain. Pain. 152: 259-66. PMID 20889259 DOI: 10.1016/J.Pain.2010.09.007 |
0.751 |
|
| 2010 |
Clark RJ, Jensen J, Nevin ST, Callaghan BP, Adams DJ, Craik DJ. The engineering of an orally active conotoxin for the treatment of neuropathic pain Angewandte Chemie - International Edition. 49: 6545-6548. PMID 20533477 DOI: 10.1002/Anie.201000620 |
0.693 |
|
| 2010 |
Callaghan B, Adams DJ. Analgesic alpha-conotoxins Vc1.1 and RgIA inhibit N-type calcium channels in sensory neurons of alpha9 nicotinic receptor knockout mice Channels (Austin, Tex.). 4: 51-54. PMID 20368690 DOI: 10.4161/Chan.4.1.10281 |
0.505 |
|
| 2010 |
Clark R, Guille V, Callaghan B, Adams D, Craik D. 167 DEVELOPMENT OF AN ORALLY ACTIVE PEPTIDE FOR THE TREATMENT OF NEUROPATHIC PAIN European Journal of Pain Supplements. 4: 50-50. DOI: 10.1016/S1754-3207(10)70172-3 |
0.474 |
|
| 2008 |
Callaghan B, Haythornthwaite A, Berecki G, Clark RJ, Craik DJ, Adams DJ. Analgesic α-conotoxins Vc1.1 and Rg1A inhibit N-type calcium channels in rat sensory neurons via GABAB receptor activation Journal of Neuroscience. 28: 10943-10951. PMID 18945902 DOI: 10.1523/Jneurosci.3594-08.2008 |
0.776 |
|
| 2007 |
Cobine CA, Callaghan BP, Keef KD. Role of L-type calcium channels and PKC in active tone development in rabbit coronary artery. American Journal of Physiology. Heart and Circulatory Physiology. 292: H3079-88. PMID 17277031 DOI: 10.1152/Ajpheart.01261.2006 |
0.739 |
|
| 2006 |
Callaghan B, Zhong J, Keef KD. Signaling pathway underlying stimulation of L-type Ca2+ channels in rabbit portal vein myocytes by recombinant Gbetagamma subunits. American Journal of Physiology. Heart and Circulatory Physiology. 291: H2541-6. PMID 16877561 DOI: 10.1152/Ajpheart.00420.2006 |
0.635 |
|
| 2004 |
Callaghan B, Koh SD, Keef KD. Muscarinic M2 receptor stimulation of Cav1.2b requires phosphatidylinositol 3-kinase, protein kinase C, and c-Src. Circulation Research. 94: 626-33. PMID 14739158 DOI: 10.1161/01.Res.0000118248.17466.B7 |
0.604 |
|
| 2003 |
Farrelly AM, Ro S, Callaghan BP, Khoyi MA, Fleming N, Horowitz B, Sanders KM, Keef KD. Expression and function of KCNH2 (HERG) in the human jejunum. American Journal of Physiology. Gastrointestinal and Liver Physiology. 284: G883-95. PMID 12736144 DOI: 10.1152/Ajpgi.00394.2002 |
0.717 |
|
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