| Year |
Citation |
Score |
| 2023 |
Gary EN, Tursi NJ, Warner BM, Cuismano G, Connors J, Parzych EM, Griffin BD, Bell MR, Ali AR, Frase D, Hojecki CE, Canziani GA, Chaiken I, Kannan T, Moffat E, ... ... Weiner DB, et al. Adenosine deaminase augments SARS-CoV-2 specific cellular and humoral responses in aged mouse models of immunization and challenge. Frontiers in Immunology. 14: 1138609. PMID 36999023 DOI: 10.3389/fimmu.2023.1138609 |
0.446 |
|
| 2023 |
Park DH, Liaw K, Bhojnagarwala P, Zhu X, Choi J, Ali AR, Bordoloi D, Gary EN, O'Connell RP, Kulkarni A, Guimet D, Smith T, Perales-Puchalt A, Patel A, Weiner DB. Multivalent delivery of DNA-encoded bispecific T cell engagers effectively controls heterogeneous GBM tumors and mitigates immune escape. Molecular Therapy Oncolytics. 28: 249-263. PMID 36915911 DOI: 10.1016/j.omto.2023.02.004 |
0.311 |
|
| 2023 |
Tursi NJ, Xu Z, Helble M, Walker S, Liaw K, Chokkalingam N, Kannan T, Wu Y, Tello-Ruiz E, Park DH, Zhu X, Wise MC, Smith TRF, Majumdar S, Kossenkov A, ... ... Weiner DB, et al. Engineered antibody cytokine chimera synergizes with DNA-launched nanoparticle vaccines to potentiate melanoma suppression . Frontiers in Immunology. 14: 1072810. PMID 36911698 DOI: 10.3389/fimmu.2023.1072810 |
0.373 |
|
| 2023 |
Tursi NJ, Xu Z, Kulp DW, Weiner DB. Gene-encoded nanoparticle vaccine platforms for in vivo assembly of multimeric antigen to promote adaptive immunity. Wiley Interdisciplinary Reviews. Nanomedicine and Nanobiotechnology. e1880. PMID 36807845 DOI: 10.1002/wnan.1880 |
0.449 |
|
| 2022 |
Jacobson JM, Zahrieh D, Strand CA, Cruz-Correa M, Pungpapong S, Roberts LR, Mandrekar SJ, Rodriguez LM, Boyer J, Marrero I, Kraynyak KA, Morrow MP, Sylvester AJ, Pawlicki JM, Gillespie E, ... ... Weiner DB, et al. Phase I Trial of a Therapeutic DNA Vaccine for Preventing Hepatocellular Carcinoma from Chronic Hepatitis C Virus (HCV) Infection. Cancer Prevention Research (Philadelphia, Pa.). OF1-OF11. PMID 36534786 DOI: 10.1158/1940-6207.CAPR-22-0217 |
0.723 |
|
| 2022 |
Gary EN, Tursi NJ, Warner B, Parzych EM, Ali AR, Frase D, Moffat E, Embury-Hyatt C, Smith TRF, Broderick KE, Humeau L, Kobasa D, Patel A, Kulp DW, Weiner DB. Mucosal chemokine adjuvant enhances synDNA vaccine-mediated responses to SARS-CoV-2 and provides heterologous protection in vivo. Cell Reports. Medicine. 100693. PMID 35839767 DOI: 10.1016/j.xcrm.2022.100693 |
0.518 |
|
| 2022 |
Cusimano GM, Gary EN, Bell MR, Warner BM, Connors J, Tursi NJ, Ali AR, Zhang S, Canziani G, Taramangalam B, Gordon EA, Chaiken IM, Wootton SK, Smith T, Ramos S, ... ... Weiner DB, et al. Improved Durability to SARS-CoV-2 Vaccine Immunity following Coimmunization with Molecular Adjuvant Adenosine Deaminase-1. Journal of Immunology (Baltimore, Md. : 1950). 209: 118-127. PMID 35750334 DOI: 10.4049/jimmunol.2200056 |
0.421 |
|
| 2022 |
Aisenberg LK, Rousseau KE, Cascino K, Massaccesi G, Aisenberg WH, Luo W, Muthumani K, Weiner DB, Whitehead SS, Chattergoon MA, Durbin AP, Cox AL. Cross-reactive antibodies facilitate innate sensing of dengue and Zika viruses. Jci Insight. PMID 35588060 DOI: 10.1172/jci.insight.151782 |
0.668 |
|
| 2022 |
Walters JN, Schouest B, Patel A, Reuschel EL, Schultheis K, Parzych E, Maricic I, Gary EN, Purwar M, Andrade VM, Doan A, Elwood D, Eblimit Z, Nguyen B, Frase D, ... ... Weiner DB, et al. Prime-boost vaccination regimens with INO-4800 and INO-4802 augment and broaden immune responses against SARS-CoV-2 in nonhuman primates. Vaccine. 40: 2960-2969. PMID 35428500 DOI: 10.1016/j.vaccine.2022.03.060 |
0.503 |
|
| 2022 |
Xu Z, Walker S, Wise MC, Chokkalingam N, Purwar M, Moore A, Tello-Ruiz E, Wu Y, Majumdar S, Konrath KM, Kulkarni A, Tursi NJ, Zaidi FI, Reuschel EL, Patel I, ... ... Weiner DB, et al. Induction of tier-2 neutralizing antibodies in mice with a DNA-encoded HIV envelope native like trimer. Nature Communications. 13: 695. PMID 35121758 DOI: 10.1038/s41467-022-28363-z |
0.479 |
|
| 2022 |
Konrath KM, Liaw K, Wu Y, Zhu X, Walker SN, Xu Z, Schultheis K, Chokkalingam N, Chawla H, Du J, Tursi NJ, Moore A, Adolf-Bryfogle J, Purwar M, Reuschel EL, ... ... Weiner DB, et al. Nucleic acid delivery of immune-focused SARS-CoV-2 nanoparticles drives rapid and potent immunogenicity capable of single-dose protection. Cell Reports. 110318. PMID 35090597 DOI: 10.1016/j.celrep.2022.110318 |
0.465 |
|
| 2022 |
Kraynyak KA, Blackwood E, Agnes J, Tebas P, Giffear M, Amante D, Reuschel EL, Purwar M, Christensen-Quick A, Liu N, Andrade VM, Diehl MC, Wani S, Lupicka M, Sylvester A, ... ... Weiner DB, et al. SARS-CoV-2 DNA Vaccine INO-4800 Induces Durable Immune Responses Capable of Being Boosted in a Phase 1 Open-Label Trial. The Journal of Infectious Diseases. PMID 35079784 DOI: 10.1093/infdis/jiac016 |
0.788 |
|
| 2022 |
Zhu X, Perales-Puchalt A, Wojtak K, Xu Z, Yun K, Bhojnagarwala PS, Bordoloi D, Park DH, Liaw K, Bah MA, Lieberman PM, Gary EN, Patel A, Weiner DB. DNA immunotherapy targeting BARF1 induces potent anti-tumor responses against Epstein-Barr-virus-associated carcinomas. Molecular Therapy Oncolytics. 24: 218-229. PMID 35071745 DOI: 10.1016/j.omto.2021.12.017 |
0.383 |
|
| 2022 |
Jiang S, Wu S, Zhao G, He Y, Bao L, Liu J, Qin C, Hou J, Ding Y, Cheng A, Jiang B, Wu J, Yan J, Humeau L, Patella A, ... Weiner DB, et al. Comparison of Wild Type DNA Sequence of Spike Protein from SARS-CoV-2 with Optimized Sequence on The Induction of Protective Responses Against SARS-Cov-2 Challenge in Mouse Model. Human Vaccines & Immunotherapeutics. 1-11. PMID 35061975 DOI: 10.1080/21645515.2021.2016201 |
0.521 |
|
| 2021 |
Andrade VM, Christensen-Quick A, Agnes J, Tur J, Reed C, Kalia R, Marrero I, Elwood D, Schultheis K, Purwar M, Reuschel E, McMullan T, Pezzoli P, Kraynyak K, Sylvester A, ... ... Weiner DB, et al. INO-4800 DNA vaccine induces neutralizing antibodies and T cell activity against global SARS-CoV-2 variants. Npj Vaccines. 6: 121. PMID 34650089 DOI: 10.1038/s41541-021-00384-7 |
0.52 |
|
| 2021 |
Patel A, Walters JN, Reuschel EL, Schultheis K, Parzych E, Gary EN, Maricic I, Purwar M, Eblimit Z, Walker SN, Guimet D, Bhojnagarwala P, Adeniji OS, Doan A, Xu Z, ... ... Weiner DB, et al. Intradermal-delivered DNA vaccine induces durable immunity mediating a reduction in viral load in a rhesus macaque SARS-CoV-2 challenge model. Cell Reports. Medicine. 100420. PMID 34604818 DOI: 10.1016/j.xcrm.2021.100420 |
0.501 |
|
| 2021 |
Tebas P, Roberts CC, Muthumani K, Reuschel EL, Kudchodkar SB, Zaidi FI, White S, Khan AS, Racine T, Choi H, Boyer J, Park YK, Trottier S, Remigio C, Krieger D, ... ... Weiner DB, et al. Safety and Immunogenicity of an Anti-Zika Virus DNA Vaccine. The New England Journal of Medicine. 385: e35. PMID 34525286 DOI: 10.1056/NEJMoa1708120 |
0.367 |
|
| 2021 |
Bordoloi D, Xu Z, Ho M, Purwar M, Bhojnagarwala P, Cassel J, Giron LB, Walker S, Kulkarni AJ, Ruiz ET, Choi J, Zaidi FI, Wu Y, Wang S, Patel A, ... ... Weiner DB, et al. Identification of Novel Neutralizing Monoclonal Antibodies against SARS-CoV-2 Spike Glycoprotein. Acs Pharmacology & Translational Science. 4: 1349-1361. PMID 34396059 DOI: 10.1021/acsptsci.1c00058 |
0.302 |
|
| 2021 |
Vonderheide RH, Kraynyak KA, Shields AF, McRee AJ, Johnson JM, Sun W, Chintakuntlawar AV, Pawlicki J, Sylvester AJ, McMullan T, Samuels R, Kim JJ, Weiner D, Boyer JD, Morrow MP, et al. Phase 1 study of safety, tolerability and immunogenicity of the human telomerase (hTERT)-encoded DNA plasmids INO-1400 and INO-1401 with or without IL-12 DNA plasmid INO-9012 in adult patients with solid tumors. Journal For Immunotherapy of Cancer. 9. PMID 34230114 DOI: 10.1136/jitc-2021-003019 |
0.692 |
|
| 2021 |
Reeder SM, Bah MA, Tursi NJ, Brooks RC, Patel A, Esquivel R, Eaton A, Jhun H, Chu J, Kim K, Xu Z, Zavala F, Weiner DB. Strategic variants of CSP delivered as SynDNA vaccines demonstrate heterogeneity of immunogenicity and protection from infection in a murine model. Infection and Immunity. IAI0072820. PMID 34152830 DOI: 10.1128/IAI.00728-20 |
0.507 |
|
| 2021 |
Bhojnagarwala PS, Perales-Puchalt A, Cooch N, Sardesai NY, Weiner DB. A synDNA vaccine delivering neoAg collections controls heterogenous, multifocal murine lung and ovarian tumors via robust T cell generation. Molecular Therapy Oncolytics. 21: 278-287. PMID 34141866 DOI: 10.1016/j.omto.2021.04.005 |
0.384 |
|
| 2021 |
Gary EN, Warner BM, Parzych EM, Griffin BD, Zhu X, Tailor N, Tursi NJ, Chan M, Purwar M, Vendramelli R, Choi J, Frost KL, Reeder S, Liaw K, Tello E, ... ... Weiner DB, et al. A novel mouse AAV6 hACE2 transduction model of wild-type SARS-CoV-2 infection studied using synDNA immunogens. Iscience. 102699. PMID 34124612 DOI: 10.1016/j.isci.2021.102699 |
0.342 |
|
| 2021 |
Patel A, Reuschel EL, Xu Z, Zaidi FI, Kim KY, Scott DP, Mendoza J, Ramos S, Stoltz R, Feldmann F, Okumura A, Meade-White K, Haddock E, Thomas T, Rosenke R, ... ... Weiner DB, et al. Intradermal delivery of a synthetic DNA vaccine protects macaques from Middle East respiratory syndrome coronavirus. Jci Insight. PMID 33886507 DOI: 10.1172/jci.insight.146082 |
0.416 |
|
| 2021 |
Bordoloi D, Xiao P, Choi H, Ho M, Perales-Puchalt A, Khoshnejad M, Kim JJ, Humeau L, Srinivasan A, Weiner DB, Muthumani K. Immunotherapy of prostate cancer using novel synthetic DNA vaccines targeting multiple tumor antigens. Genes & Cancer. 12: 51-64. PMID 33884106 DOI: 10.18632/genesandcancer.214 |
0.321 |
|
| 2021 |
Adeniji OS, Giron LB, Purwar M, Zilberstein NF, Kulkarni AJ, Shaikh MW, Balk RA, Moy JN, Forsyth CB, Liu Q, Dweep H, Kossenkov A, Weiner DB, Keshavarzian A, Landay A, et al. COVID-19 Severity Is Associated with Differential Antibody Fc-Mediated Innate Immune Functions. Mbio. 12. PMID 33879594 DOI: 10.1128/mBio.00281-21 |
0.314 |
|
| 2021 |
Jiang J, Ramos SJ, Bangalore P, Elwood D, Cashman KA, Kudchodkar SB, Schultheis K, Pugh H, Walters J, Tur J, Yan J, Patel A, Muthumani K, Schmaljohn CS, Weiner DB, et al. Multivalent DNA Vaccines as A Strategy to Combat Multiple Concurrent Epidemics: Mosquito-Borne and Hemorrhagic Fever Viruses. Viruses. 13. PMID 33673603 DOI: 10.3390/v13030382 |
0.509 |
|
| 2020 |
Xu Z, Patel A, Tursi NJ, Zhu X, Muthumani K, Kulp DW, Weiner DB. Harnessing Recent Advances in Synthetic DNA and Electroporation Technologies for Rapid Vaccine Development Against COVID-19 and Other Emerging Infectious Diseases. Frontiers in Medical Technology. 2: 571030. PMID 35047878 DOI: 10.3389/fmedt.2020.571030 |
0.48 |
|
| 2020 |
Tebas P, Yang S, Boyer JD, Reuschel EL, Patel A, Christensen-Quick A, Andrade VM, Morrow MP, Kraynyak K, Agnes J, Purwar M, Sylvester A, Gillespie E, Maricic I, Zaidi FI, ... ... Weiner DB, et al. Safety and immunogenicity of INO-4800 DNA vaccine against SARS-CoV-2: A preliminary report of an open-label, Phase 1 clinical trial. Eclinicalmedicine. 100689. PMID 33392485 DOI: 10.1016/j.eclinm.2020.100689 |
0.764 |
|
| 2020 |
Edupuganti S, C De Rosa S, Elizaga M, Lu Y, Han X, Huang Y, Swann E, Polakowski L, A Kalams S, Keefer M, Maenza J, C Wise M, Yan J, Morrow MP, Khan AS, ... ... Weiner DB, et al. Intramuscular and Intradermal Electroporation of HIV-1 PENNVAX-GP DNA Vaccine and IL-12 Is Safe, Tolerable, Acceptable in Healthy Adults. Vaccines. 8. PMID 33297341 DOI: 10.3390/vaccines8040741 |
0.458 |
|
| 2020 |
Choi H, Kudchodkar SB, Ho M, Reuschel EL, Reynolds E, Xu Z, Bordoloi D, Ugen KE, Tebas P, Kim J, Abdel-Mohsen M, Thangamani S, Weiner DB, Muthumani K. A novel synthetic DNA vaccine elicits protective immune responses against Powassan virus. Plos Neglected Tropical Diseases. 14: e0008788. PMID 33119599 DOI: 10.1371/journal.pntd.0008788 |
0.481 |
|
| 2020 |
Xu Z, Chokkalingam N, Tello-Ruiz E, Wise MC, Bah MA, Walker S, Tursi NJ, Fisher PD, Schultheis K, Broderick KE, Humeau L, Kulp DW, Weiner DB. A DNA-launched nanoparticle vaccine elicits CD8+ T-cell immunity to promote in vivo tumor control. Cancer Immunology Research. PMID 32913042 DOI: 10.1158/2326-6066.Cir-20-0061 |
0.585 |
|
| 2020 |
Khoshnejad M, Dia Y, Patel A, Xu Z, Zhu X, Yun K, Wojtak K, Qureshi R, Humeau L, Muthumani K, Weiner DB. DNA-Encoded Glutamine Synthetase Enzyme as Ammonia-Lowering Therapeutic for Hyperammonemia. Nucleic Acid Therapeutics. PMID 32907467 DOI: 10.1089/Nat.2020.0886 |
0.328 |
|
| 2020 |
Walker SN, Chokkalingam N, Reuschel EL, Purwar M, Xu Z, Gary EN, Kim KY, Helble M, Schultheis K, Walters J, Ramos S, Muthumani K, Smith TRF, Broderick KE, Tebas P, ... ... Weiner DB, et al. SARS-CoV-2 assays to detect functional antibody responses that block ACE2 recognition in vaccinated animals and infected patients. Journal of Clinical Microbiology. PMID 32855181 DOI: 10.1128/Jcm.01533-20 |
0.442 |
|
| 2020 |
Khoshnejad M, Perales-Puchalt A, Dia Y, Xiao P, Patel A, Xu Z, Zhu X, Yun K, Baboo I, Qureshi R, Humeau L, Muthumani K, Weiner DB. Synthetic DNA Delivery of an Engineered Arginase Enzyme Can Modulate Specific Immunity . Molecular Therapy. Methods & Clinical Development. 18: 652-663. PMID 32802913 DOI: 10.1016/J.Omtm.2020.05.025 |
0.493 |
|
| 2020 |
Guibinga GH, Sahay B, Brown H, Cooch N, Chen J, Yan J, Reed C, Mishra M, Yung B, Pugh H, Schultheis K, Esquivel RN, Weiner DB, Humeau LH, Broderick KE, et al. Protection against infection mediated by a synthetically engineered DNA vaccine. Human Vaccines & Immunotherapeutics. 1-9. PMID 32783701 DOI: 10.1080/21645515.2020.1789408 |
0.569 |
|
| 2020 |
Xu Z, Chokkalingam N, Tello-Ruiz E, Walker S, Kulp DW, Weiner DB. Incorporation of a Novel CD4+ Helper Epitope Identified from Aquifex aeolicus Enhances Humoral Responses Induced by DNA and Protein Vaccinations. Iscience. 101399. PMID 32763137 DOI: 10.1016/J.Isci.2020.101399 |
0.563 |
|
| 2020 |
McNee A, Smith TRF, Holzer B, Clark B, Bessell E, Guibinga G, Brown H, Schultheis K, Fisher P, Ramos S, Nunez A, Bernard M, Graham S, Martini V, Chrun T, ... ... Weiner DB, et al. Establishment of a Pig Influenza Challenge Model for Evaluation of Monoclonal Antibody Delivery Platforms. Journal of Immunology (Baltimore, Md. : 1950). PMID 32591390 DOI: 10.4049/Jimmunol.2000429 |
0.369 |
|
| 2020 |
Schultheis K, Pugh HM, Oh J, Nguyen J, Yung B, Reed C, Cooch N, Chen J, Yan J, Muthumani K, Humeau LM, Weiner DB, Broderick KE, Smith TRF. Active immunoprophylaxis with a synthetic DNA-encoded monoclonal anti-respiratory syncytial virus scFv-Fc fusion protein confers protection against infection and durable activity. Human Vaccines & Immunotherapeutics. 1-11. PMID 32544376 DOI: 10.1080/21645515.2020.1748979 |
0.422 |
|
| 2020 |
Zankharia US, Kudchodkar S, Khoshnejad M, Perales-Puchalt A, Choi H, Ho M, Zaidi F, Ugen KE, Kim JJ, Weiner DB, Muthumani K. Neutralization of hepatitis B virus by a novel DNA-encoded monoclonal antibody. Human Vaccines & Immunotherapeutics. 1-9. PMID 32463327 DOI: 10.1080/21645515.2020.1763686 |
0.326 |
|
| 2020 |
DeRosa S, Edupuganti S, Huang Y, Han X, Elizaga M, Swann E, Polakowski L, Kalams SA, Keefer MC, Maenza J, Lu Y, Wise MC, Yan J, Morrow MP, Khan AS, ... ... Weiner DB, et al. Robust antibody and cellular responses induced by DNA-only vaccination for HIV. Jci Insight. PMID 32437332 DOI: 10.1172/Jci.Insight.137079 |
0.528 |
|
| 2020 |
Smith TRF, Patel A, Ramos S, Elwood D, Zhu X, Yan J, Gary EN, Walker SN, Schultheis K, Purwar M, Xu Z, Walters J, Bhojnagarwala P, Yang M, Chokkalingam N, ... ... Weiner DB, et al. Immunogenicity of a DNA vaccine candidate for COVID-19. Nature Communications. 11: 2601. PMID 32433465 DOI: 10.1038/S41467-020-16505-0 |
0.559 |
|
| 2020 |
Xu Z, Wise MC, Chokkalingam N, Walker S, Tello-Ruiz E, Elliott STC, Perales-Puchalt A, Xiao P, Zhu X, Pumroy RA, Fisher PD, Schultheis K, Schade E, Menis S, Guzman S, ... ... Weiner DB, et al. In Vivo Assembly of Nanoparticles Achieved through Synergy of Structure-Based Protein Engineering and Synthetic DNA Generates Enhanced Adaptive Immunity. Advanced Science (Weinheim, Baden-Wurttemberg, Germany). 7: 1902802. PMID 32328416 DOI: 10.1002/Advs.201902802 |
0.557 |
|
| 2020 |
Gary EN, Weiner DB. DNA vaccines: prime time is now. Current Opinion in Immunology. 65: 21-27. PMID 32259744 DOI: 10.1016/J.Coi.2020.01.006 |
0.503 |
|
| 2020 |
Shore ND, Morrow MP, McMullan T, Kraynyak KA, Sylvester A, Bhatt K, Cheung J, Boyer JD, Liu L, Sacchetta B, Rosencranz S, Heath EI, Nordquist L, Cheng HH, Tagawa ST, ... ... Weiner DB, et al. CD8 T Cells Impact Rising PSA in Biochemically Relapsed Cancer Patients Using Immunotherapy Targeting Tumor-Associated Antigens. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 32208168 DOI: 10.1016/J.Ymthe.2020.02.018 |
0.691 |
|
| 2020 |
Patel A, Bah MA, Weiner DB. In Vivo Delivery of Nucleic Acid-Encoded Monoclonal Antibodies. Biodrugs : Clinical Immunotherapeutics, Biopharmaceuticals and Gene Therapy. PMID 32157600 DOI: 10.1007/S40259-020-00412-3 |
0.333 |
|
| 2020 |
Han JW, Sung PS, Hong SH, Lee H, Koh JY, Lee H, White S, Maslow JN, Weiner DB, Park SH, Jeong M, Heo J, Ahn SH, Shin EC. IFNL3-adjuvanted HCV DNA vaccine reduces regulatory T-cell frequency and increases virus-specific T-cell responses. Journal of Hepatology. PMID 32088322 DOI: 10.1016/J.Jhep.2020.02.009 |
0.435 |
|
| 2020 |
Gary EN, Kathuria N, Makurumidze G, Curatola A, Ramamurthi A, Bernui ME, Myles D, Yan J, Pankhong P, Muthumani K, Haddad E, Humeau L, Weiner DB, Kutzler MA. CCR10 expression is required for the adjuvant activity of the mucosal chemokine CCL28 when delivered in the context of an HIV-1 Env DNA vaccine. Vaccine. PMID 32057572 DOI: 10.1016/J.Vaccine.2020.01.023 |
0.518 |
|
| 2020 |
Aggarwal C, Cohen RB, Morrow MP, Kraynyak KA, Sylvester AJ, Cheung J, Dickerson K, Schulten V, Knoblock D, Gillespie E, Bauml JM, Yan J, Diehl M, Boyer J, Dallas M, ... ... Weiner DB, et al. Immune Therapy Targeting E6/E7 Oncogenes of Human Paillomavirus Type 6 (HPV-6) Reduces or Eliminates the Need for Surgical Intervention in the Treatment of HPV-6 Associated Recurrent Respiratory Papillomatosis. Vaccines. 8. PMID 32013270 DOI: 10.3390/Vaccines8010056 |
0.703 |
|
| 2020 |
Reeder SM, Reuschel EL, Bah MA, Yun K, Tursi NJ, Kim KY, Chu J, Zaidi FI, Yilmaz I, Hart RJ, Perrin B, Xu Z, Humeau L, Weiner DB, Aly ASI. Synthetic DNA Vaccines Adjuvanted with pIL-33 Drive Liver-Localized T Cells and Provide Protection from Challenge in a Mouse Model. Vaccines. 8. PMID 31936739 DOI: 10.3390/Vaccines8010021 |
0.569 |
|
| 2020 |
Xu Z, Patel A, Tursi NJ, Zhu X, Muthumani K, Kulp DW, Weiner DB. Harnessing Recent Advances in Synthetic DNA and Electroporation Technologies for Rapid Vaccine Development Against COVID-19 and Other Emerging Infectious Diseases Frontiers in Medical Technology. 2. DOI: 10.3389/fmedt.2020.571030 |
0.358 |
|
| 2020 |
Reardon DA, Brem S, Desai AS, Bagley SJ, Kurz SC, De La Fuente MI, Nagpal S, Welch MR, Hormigo A, Carroll N, Bartra SK, Campbell P, Bhatt K, Lowy I, Boyer J, ... ... Weiner DB, et al. INO-5401 and INO-9012 delivered intramuscularly (IM) with electroporation (EP) in combination with cemiplimab (REGN2810) in newly diagnosed glioblastoma (GBM): Interim results. Journal of Clinical Oncology. 38: 2514-2514. DOI: 10.1200/Jco.2020.38.15_Suppl.2514 |
0.703 |
|
| 2020 |
Duperret EK, Perales-Puchalt A, Stoltz R, Hiranjith GH, Mandloi N, Barlow J, Chaudhuri A, Sardesai NY, Weiner DB. Abstract B67: Synthetic DNA multi-neoantigen vaccine drives predominately MHC class I CD8+ T cell-mediated effector immunity impacting tumor challenge Cancer Immunology Research. 8. DOI: 10.1158/2326-6074.Tumimm18-B67 |
0.535 |
|
| 2020 |
Aggarwal C, Cohen RB, Morrow MP, Kraynyak KA, Cheung J, Dickerson K, Schulten V, Knoblock D, Gillespie E, Bauml JM, Diehl M, Boyer J, Dallas M, Weiner DB, Skolnik JM. Abstract CT126: A synthetic DNA plasmid encoding HPV6 E6 and E7 proteins in patients with HPV6-associated aerodigestive lesions Tumor Biology. DOI: 10.1158/1538-7445.Am2020-Ct126 |
0.67 |
|
| 2020 |
Xu Z, Wise MC, Chokkalingam N, Walker S, Tello‐Ruiz E, Elliott STC, Perales‐Puchalt A, Xiao P, Zhu X, Pumroy RA, Fisher PD, Schultheis K, Schade E, Menis S, Guzman S, ... ... Weiner DB, et al. Nanoparticle Vaccines: In Vivo Assembly of Nanoparticles Achieved through Synergy of Structure‐Based Protein Engineering and Synthetic DNA Generates Enhanced Adaptive Immunity (Adv. Sci. 8/2020) Advanced Science. 7: 2070044. DOI: 10.1002/Advs.202070044 |
0.429 |
|
| 2019 |
Choi H, Kudchodkar SB, Reuschel EL, Asija K, Borole P, Agarwal S, Van Gorder L, Reed CC, Gulendran G, Ramos S, Broderick KE, Kim JJ, Ugen KE, Kobinger G, Siegel DL, ... Weiner DB, et al. Synthetic nucleic acid antibody prophylaxis confers rapid and durable protective immunity against Zika virus challenge. Human Vaccines & Immunotherapeutics. 1-12. PMID 31799896 DOI: 10.1080/21645515.2019.1688038 |
0.58 |
|
| 2019 |
Wise MC, Xu Z, Tello-Ruiz E, Beck C, Trautz A, Patel A, Elliott ST, Chokkalingam N, Kim S, Kerkau MG, Muthumani K, Jiang J, Fisher P, Ramos SJ, Smith TR, ... ... Weiner DB, et al. In vivo delivery of synthetic DNA-encoded antibodies induces broad HIV-1-neutralizing activity. The Journal of Clinical Investigation. PMID 31697648 DOI: 10.1172/Jci132779 |
0.381 |
|
| 2019 |
Cable J, Srikantiah P, Crowe JE, Pulendran B, Hill A, Ginsberg A, Koff W, Mathew A, Ng T, Jansen K, Glenn G, Permar S, Wilson I, Weiner DB, Weissman D, et al. Vaccine innovations for emerging infectious diseases-a symposium report. Annals of the New York Academy of Sciences. PMID 31659752 DOI: 10.1111/Nyas.14235 |
0.486 |
|
| 2019 |
Abdulhaqq SA, Martinez M, Kang G, Rodriguez IV, Nichols SM, Beaumont D, Joseph J, Azzoni L, Yin X, Wise M, Weiner D, Liu Q, Foulkes A, Münch J, Kirchhoff F, et al. Repeated semen exposure decreases cervicovaginal SIVmac251 infection in rhesus macaques. Nature Communications. 10: 3753. PMID 31434895 DOI: 10.1038/S41467-019-11814-5 |
0.339 |
|
| 2019 |
Modjarrad K, Roberts CC, Mills KT, Castellano AR, Paolino K, Muthumani K, Reuschel EL, Robb ML, Racine T, Oh MD, Lamarre C, Zaidi FI, Boyer J, Kudchodkar SB, Jeong M, ... ... Weiner DB, et al. Safety and immunogenicity of an anti-Middle East respiratory syndrome coronavirus DNA vaccine: a phase 1, open-label, single-arm, dose-escalation trial. The Lancet. Infectious Diseases. PMID 31351922 DOI: 10.1016/S1473-3099(19)30266-X |
0.482 |
|
| 2019 |
Louis L, Clark M, Wise MC, Glennie N, Wong A, Broderick K, Uzonna J, Weiner DB, Scott P. Intradermal synDNA vaccination generates Leishmania specific T cells in the skin and protection against . Infection and Immunity. PMID 31182618 DOI: 10.1128/Iai.00227-19 |
0.585 |
|
| 2019 |
Jiang J, Ramos SJ, Bangalore P, Fisher P, Germar K, Lee BK, Williamson D, Kemme A, Schade E, McCoy J, Muthumani K, Weiner DB, Humeau LM, Broderick KE. Integration of needle-free jet injection with advanced electroporation delivery enhances the magnitude, kinetics, and persistence of engineered DNA vaccine induced immune responses. Vaccine. PMID 31174938 DOI: 10.1016/J.Vaccine.2019.05.054 |
0.558 |
|
| 2019 |
Wojtak K, Perales-Puchalt A, Weiner DB. Novel Synthetic DNA Immunogens Targeting Latent Expressed Antigens of Epstein-Barr Virus Elicit Potent Cellular Responses and Inhibit Tumor Growth. Vaccines. 7. PMID 31137606 DOI: 10.3390/Vaccines7020044 |
0.557 |
|
| 2019 |
Louis L, Wise MC, Choi H, Villarreal DO, Muthumani K, Weiner DB. Designed DNA-Encoded IL-36 Gamma Acts as a Potent Molecular Adjuvant Enhancing Zika Synthetic DNA Vaccine-Induced Immunity and Protection in a Lethal Challenge Model. Vaccines. 7. PMID 31121939 DOI: 10.3390/Vaccines7020042 |
0.592 |
|
| 2019 |
Perales-Puchalt A, Duperret EK, Yang X, Hernandez P, Wojtak K, Zhu X, Jung SH, Tello-Ruiz E, Wise MC, Montaner LJ, Muthumani K, Weiner DB. DNA-encoded bispecific T cell engagers and antibodies present long-term antitumor activity. Jci Insight. 4. PMID 30996140 DOI: 10.1172/Jci.Insight.126086 |
0.381 |
|
| 2019 |
Esquivel RN, Patel A, Kudchodkar SB, Park DH, Stettler K, Beltramello M, Allen JW, Mendoza J, Ramos S, Choi H, Borole P, Asija K, Bah M, Shaheen S, Chen J, ... ... Weiner DB, et al. In Vivo Delivery of a DNA-Encoded Monoclonal Antibody Protects Non-human Primates against Zika Virus. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 30962164 DOI: 10.1016/J.Ymthe.2019.03.005 |
0.392 |
|
| 2019 |
Tebas P, Kraynyak KA, Patel A, Maslow JN, Morrow MP, Sylvester AJ, Knoblock D, Gillespie E, Amante D, Racine T, McMullan T, Jeong M, Roberts CC, Park YK, Boyer J, ... ... Weiner DB, et al. Intradermal SynCon® Ebola GP DNA Vaccine is Temperature Stable and Safely Demonstrates Cellular and Humoral Immunogenicity Advantages in Healthy Volunteers. The Journal of Infectious Diseases. PMID 30891607 DOI: 10.1093/Infdis/Jiz132 |
0.778 |
|
| 2019 |
Schommer NN, Nguyen J, Yung BS, Schultheis K, Muthumani K, Weiner D, Humeau L, Broderick KE, Smith TRF. Active immunoprophylaxis and vaccine augmentations mediated by a novel plasmid DNA formulation. Human Gene Therapy. PMID 30860399 DOI: 10.1089/Hum.2018.241 |
0.403 |
|
| 2019 |
Choi H, Kudchodkar SB, Reuschel EL, Asija K, Borole P, Ho M, Wojtak K, Reed C, Ramos S, Bopp NE, Aguilar PV, Weaver SC, Kim JJ, Humeau L, Tebas P, ... Weiner DB, et al. Protective immunity by an engineered DNA vaccine for Mayaro virus. Plos Neglected Tropical Diseases. 13: e0007042. PMID 30730897 DOI: 10.1371/Journal.Pntd.0007042 |
0.576 |
|
| 2019 |
Perales-Puchalt A, Duperret EK, Muthumani K, Weiner DB. Simplifying checkpoint inhibitor delivery through generation of synthetic DNA-encoded monoclonal antibodies (DMAbs). Oncotarget. 10: 13-16. PMID 30713599 DOI: 10.18632/Oncotarget.26535 |
0.371 |
|
| 2019 |
Duperret EK, Perales-Puchalt A, Stoltz R, G H H, Mandloi N, Barlow J, Chaudhuri A, Sardesai NY, Weiner DB. A Synthetic DNA, Multi-Neoantigen Vaccine Drives Predominately MHC Class I CD8 T-cell Responses, Impacting Tumor Challenge. Cancer Immunology Research. 7: 174-182. PMID 30679156 DOI: 10.1158/2326-6066.Cir-18-0283 |
0.553 |
|
| 2019 |
Perales-Puchalt A, Svoronos N, Villarreal DO, Zankharia U, Reuschel E, Wojtak K, Payne KK, Duperret EK, Muthumani K, Conejo-Garcia JR, Weiner DB. IL-33 delays metastatic peritoneal cancer progression inducing an allergic microenvironment. Oncoimmunology. 8: e1515058. PMID 30546956 DOI: 10.1080/2162402X.2018.1515058 |
0.333 |
|
| 2019 |
Perales-Puchalt A, Duperret EK, Muthumani K, Weiner DB, Yang X, Zhu X, Wojtak K, Tello-Ruiz E, Wise MC. Abstract 1547: DNA-encoded bispecific T-cell engagers and antibodies present long-term antitumor activity Immunology. DOI: 10.1158/1538-7445.Sabcs18-1547 |
0.354 |
|
| 2018 |
Perales-Puchalt A, Wojtak K, Duperret EK, Yang X, Slager AM, Yan J, Muthumani K, Montaner LJ, Weiner DB. Engineered DNA Vaccination against Follicle-Stimulating Hormone Receptor Delays Ovarian Cancer Progression in Animal Models. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 30554854 DOI: 10.1016/J.Ymthe.2018.11.014 |
0.536 |
|
| 2018 |
Wang Y, Esquivel R, Flingai S, Schiller ZA, Kern A, Agarwal S, Chu J, Patel A, Sullivan K, Wise MC, Broderick KE, Hu L, Weiner DB, Klempner MS. Anti-OspA DNA-Encoded Monoclonal Antibody Prevents Transmission of Spirochetes in Tick Challenge Providing Sterilizing Immunity in Mice. The Journal of Infectious Diseases. PMID 30476132 DOI: 10.1093/Infdis/Jiy627 |
0.392 |
|
| 2018 |
Patel A, Park DH, Davis CW, Smith TRF, Leung A, Tierney K, Bryan A, Davidson E, Yu X, Racine T, Reed C, Gorman ME, Wise MC, Elliott STC, Esquivel R, ... ... Weiner DB, et al. In Vivo Delivery of Synthetic Human DNA-Encoded Monoclonal Antibodies Protect against Ebolavirus Infection in a Mouse Model. Cell Reports. 25: 1982-1993.e4. PMID 30428362 DOI: 10.1016/J.Celrep.2018.10.062 |
0.379 |
|
| 2018 |
Patel A, Reuschel EL, Kraynyak KA, Racine T, Park DH, Scott VL, Audet J, Amante D, Wise MC, Keaton AA, Wong G, Villarreal DO, Walters J, Muthumani K, Shedlock DJ, ... ... Weiner DB, et al. Protective Efficacy and Long-Term Immunogenicity in Cynomolgus Macaques by Ebola Virus Glycoprotein Synthetic DNA Vaccines. The Journal of Infectious Diseases. PMID 30304515 DOI: 10.1093/Infdis/Jiy537 |
0.791 |
|
| 2018 |
Duperret EK, Trautz A, Stoltz R, Patel A, Wise MC, Perales-Puchalt A, Smith T, Broderick KE, Masteller EL, Kim JJ, Humeau L, Muthumani K, Weiner DB. Synthetic DNA-encoded monoclonal antibody delivery of anti-CTLA-4 antibodies induces tumor shrinkage in vivo. Cancer Research. PMID 30287678 DOI: 10.1158/0008-5472.Can-18-1429 |
0.397 |
|
| 2018 |
Duperret EK, Liu S, Paik MJ, Trautz A, Stoltz R, Liu X, Ze K, Perales-Puchalt A, Reed C, Yan J, Xu X, Weiner DB. A designer cross-reactive DNA immunotherapeutic vaccine that targets multiple MAGE-A family members simultaneously for cancer therapy. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 30262507 DOI: 10.1158/1078-0432.Ccr-18-1013 |
0.4 |
|
| 2018 |
Aggarwal C, Cohen RB, Morrow MP, Kraynak KA, Sylvester AJ, Knoblock DM, Bauml J, Weinstein GS, Lin A, Boyer J, Sakata L, Tan S, Anton A, Dickerson K, Mangrolia D, ... ... Weiner DB, et al. Immunotherapy targeting HPV 16/18 generates potent immune responses in HPV-Associated Head and Neck Cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 30242022 DOI: 10.1158/1078-0432.Ccr-18-1763 |
0.369 |
|
| 2018 |
Xu Z, Wise MC, Choi H, Perales-Puchalt A, Patel A, Tello-Ruiz E, Chu JD, Muthumani K, Weiner DB. Synthetic DNA delivery by electroporation promotes robust in vivo sulfation of broadly neutralizing anti-HIV immunoadhesin eCD4-Ig. Ebiomedicine. PMID 30174283 DOI: 10.1016/J.Ebiom.2018.08.027 |
0.421 |
|
| 2018 |
Elliott S, Keaton AA, Chu JD, Reed CC, Garman B, Patel A, Yan J, Broderick KE, Weiner D. A Synthetic Micro-Consensus DNA Vaccine Generates Comprehensive Influenza-A H3N2 Immunity and Protects Mice Against Lethal Challenge by Multiple H3N2 Viruses. Human Gene Therapy. PMID 30062926 DOI: 10.1089/Hum.2018.102 |
0.547 |
|
| 2018 |
de La Vega MA, Piret J, Griffin BD, Rhéaume C, Venable MC, Carbonneau J, Couture C, das Neves Almeida R, Tremblay RR, Magalhães KG, Park YK, Roberts CC, Maslow JN, Sardesai NY, Kim JJ, ... ... Weiner DB, et al. Zika-Induced Male Infertility in Mice Is Potentially Reversible and Preventable by Deoxyribonucleic Acid Immunization. The Journal of Infectious Diseases. PMID 30053014 DOI: 10.1093/Infdis/Jiy336 |
0.341 |
|
| 2018 |
Kudchodkar SB, Choi H, Reuschel EL, Esquivel R, Jin-Ah Kwon J, Jeong M, Maslow JN, Reed CC, White S, Kim JJ, Kobinger GP, Tebas P, Weiner DB, Muthumani K. Rapid response to an emerging infectious disease - Lessons learned from development of a synthetic DNA vaccine targeting Zika virus. Microbes and Infection. PMID 29555345 DOI: 10.1016/J.Micinf.2018.03.001 |
0.49 |
|
| 2018 |
Elliott ST, Weiner DB. Herd immunity: hyperimmune globulins for the 21st century. The Lancet. Infectious Diseases. PMID 29329956 DOI: 10.1016/S1473-3099(18)30003-3 |
0.4 |
|
| 2018 |
Duperret EK, Trautz A, Paik M, Reed C, Yan J, Weiner DB. Abstract B113: Development of a novel synthetic consensus DNA vaccine that targets multiple MAGE-A family members for anticancer immune therapy Molecular Cancer Therapeutics. 17. DOI: 10.1158/1535-7163.Targ-17-B113 |
0.467 |
|
| 2018 |
Duperret E, Trautz A, Patel A, Kim J, Muthumani K, Weiner DB. Abstract B036: Synthetic DNA-encoded monoclonal antibody delivery (DMAbTM) of anti-CTLA4 antibodies induces tumor shrinkage in vivo Molecular Cancer Therapeutics. 17. DOI: 10.1158/1535-7163.Targ-17-B036 |
0.437 |
|
| 2017 |
Duperret EK, Trautz A, Ammons D, Perales-Puchalt A, Wise MC, Yan J, Reed C, Weiner DB. Alteration of the tumor stroma using a consensus DNA vaccine targeting Fibroblast Activation Protein (FAP) synergizes with anti-tumor vaccine therapy in mice. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 29269377 DOI: 10.1158/1078-0432.Ccr-17-2033 |
0.489 |
|
| 2017 |
Elliott STC, Kallewaard NL, Benjamin E, Wachter-Rosati L, McAuliffe JM, Patel A, Smith TRF, Schultheis K, Park DH, Flingai S, Wise MC, Mendoza J, Ramos S, Broderick KE, Yan J, ... ... Weiner DB, et al. DMAb inoculation of synthetic cross reactive antibodies protects against lethal influenza A and B infections. Npj Vaccines. 2: 18. PMID 29263874 DOI: 10.1038/s41541-017-0020-x |
0.337 |
|
| 2017 |
Duperret EK, Wise MC, Trautz A, Villarreal DO, Ferraro B, Walters J, Yan J, Khan A, Masteller E, Humeau L, Weiner DB. Synergy of Immune Checkpoint Blockade with a Novel Synthetic Consensus DNA Vaccine Targeting TERT. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 29249395 DOI: 10.1016/J.Ymthe.2017.11.010 |
0.589 |
|
| 2017 |
Veglia F, Tyurin VA, Mohammadyani D, Blasi M, Duperret EK, Donthireddy L, Hashimoto A, Kapralov A, Amoscato A, Angelini R, Patel S, Alicea-Torres K, Weiner D, Murphy ME, Klein-Seetharaman J, et al. Lipid bodies containing oxidatively truncated lipids block antigen cross-presentation by dendritic cells in cancer. Nature Communications. 8: 2122. PMID 29242535 DOI: 10.1038/S41467-017-02186-9 |
0.338 |
|
| 2017 |
Yan J, Morrow MP, Chu JS, Racine T, Reed CC, Khan AS, Broderick KE, Kim JJ, Kobinger GP, Sardesai NY, Weiner DB. Broad cross-protective anti-hemagglutination responses elicited by influenza microconsensus DNA vaccine. Vaccine. PMID 29100705 DOI: 10.1016/J.Vaccine.2017.09.086 |
0.542 |
|
| 2017 |
Morrow MP, Kraynyak K, Sylvester AJ, Dallas M, Knoblock D, Boyer J, Yan J, Vang R, Khan AS, Humeau L, Sardesai NY, Kim JJ, Plotkin S, Weiner D, Trimble CL, et al. Clinical and Immunological Biomarkers for Histologic Regression of High Grade Cervical Dysplasia and Clearance of HPV16 and HPV18 after Immunotherapy. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 29084917 DOI: 10.1158/1078-0432.Ccr-17-2335 |
0.66 |
|
| 2017 |
Tebas P, Roberts CC, Muthumani K, Reuschel EL, Kudchodkar SB, Zaidi FI, White S, Khan AS, Racine T, Choi H, Boyer J, Park YK, Trottier S, Remigio C, Krieger D, ... ... Weiner DB, et al. Safety and Immunogenicity of an Anti-Zika Virus DNA Vaccine - Preliminary Report. The New England Journal of Medicine. PMID 28976850 DOI: 10.1056/Nejmoa1708120 |
0.54 |
|
| 2017 |
Ake JA, Schuetz A, Pegu P, Wieczorek L, Eller MA, Kibuuka H, Sawe F, Maboko L, Polonis V, Karasavva N, Weiner D, Sekiziyivu A, Kosgei J, Missanga M, Kroidl A, et al. Safety and Immunogenicity of PENNVAX®-G DNA Prime Administered by Biojector® 2000 or CELLECTRA® Electroporation Device with Modified Vaccinia Ankara-CMDR Boost. The Journal of Infectious Diseases. PMID 28968759 DOI: 10.1093/Infdis/Jix456 |
0.445 |
|
| 2017 |
Patel A, DiGiandomenico A, Keller AE, Smith TRF, Park DH, Ramos S, Schultheis K, Elliott STC, Mendoza J, Broderick KE, Wise MC, Yan J, Jiang J, Flingai S, Khan AS, ... ... Weiner DB, et al. An engineered bispecific DNA-encoded IgG antibody protects against Pseudomonas aeruginosa in a pneumonia challenge model. Nature Communications. 8: 637. PMID 28935938 DOI: 10.1038/S41467-017-00576-7 |
0.396 |
|
| 2017 |
Muthumani K, Marnin L, Kudchodkar SB, Perales-Puchalt A, Choi H, Agarwal S, Scott VL, Reuschel EL, Zaidi FI, Duperret EK, Wise MC, Kraynyak KA, Ugen KE, Sardesai NY, Joseph Kim J, ... Weiner DB, et al. Novel prostate cancer immunotherapy with a DNA-encoded anti-prostate-specific membrane antigen monoclonal antibody. Cancer Immunology, Immunotherapy : Cii. PMID 28819703 DOI: 10.1007/S00262-017-2042-7 |
0.712 |
|
| 2017 |
Griffin BD, Muthumani K, Warner BM, Majer A, Hagan M, Audet J, Stein DR, Ranadheera C, Racine T, De La Vega MA, Piret J, Kucas S, Tran KN, Frost KL, De Graff C, ... ... Weiner DB, et al. DNA vaccination protects mice against Zika virus-induced damage to the testes. Nature Communications. 8: 15743. PMID 28589934 DOI: 10.1038/Ncomms15743 |
0.51 |
|
| 2017 |
Smith TRF, Schultheis K, Morrow MP, Kraynyak KA, McCoy JR, Yim KC, Muthumani K, Humeau L, Weiner DB, Sardesai NY, Broderick KE. Development of an intradermal DNA vaccine delivery strategy to achieve single-dose immunity against respiratory syncytial virus. Vaccine. PMID 28413132 DOI: 10.1016/J.Vaccine.2017.04.008 |
0.796 |
|
| 2017 |
Lee H, Jeong M, Oh J, Cho Y, Shen X, Stone J, Yan J, Rothkopf Z, Khan AS, Cho BM, Park YK, Weiner DB, Son WC, Maslow JN. Preclinical evaluation of multi antigenic HCV DNA vaccine for the prevention of Hepatitis C virus infection. Scientific Reports. 7: 43531. PMID 28266565 DOI: 10.1038/Srep43531 |
0.48 |
|
| 2017 |
Walters JN, Ferraro B, Duperret EK, Kraynyak KA, Chu J, Saint-Fleur A, Yan J, Levitsky H, Khan AS, Sardesai NY, Weiner DB. A Novel DNA Vaccine Platform Enhances Neo-antigen-like T Cell Responses against WT1 to Break Tolerance and Induce Anti-tumor Immunity. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 28237837 DOI: 10.1016/J.Ymthe.2017.01.022 |
0.819 |
|
| 2017 |
Aggarwal C, Cohen RB, Morrow MP, Kraynyak K, Bauml J, Weinstein GS, Boyer J, Yan J, Mangrolia D, Oyola S, Duff S, Weiner DB, Csiki I, Bagarazzi ML. Immunogenicity results using human papillomavirus (HPV) specific DNA vaccine, INO-3112 (HPV16/HPV18 plasmids + IL-12) in HPV+ head and neck squamous cell carcinoma (HNSCCa). Journal of Clinical Oncology. 35: 6073-6073. DOI: 10.1200/Jco.2017.35.15_Suppl.6073 |
0.708 |
|
| 2017 |
Tebas P, Roberts CC, Muthumani K, Reuschel E, White S, Khan AS, Racine T, Choi H, Zaidi F, Boyer J, Kudchodkar S, Park YK, Trottier S, Remigio C, Krieger D, ... ... Weiner D, et al. ZIKA-001: Safety and Immunogenicity of an Engineered DNA Vaccine Against ZIKA virus infection Open Forum Infectious Diseases. 4: S300-S301. DOI: 10.1093/Ofid/Ofx163.693 |
0.479 |
|
| 2016 |
Muthumani K, Griffin BD, Agarwal S, Kudchodkar SB, Reuschel EL, Choi H, Kraynyak KA, Duperret EK, Keaton AA, Chung C, Kim YK, Booth SA, Racine T, Yan J, Morrow MP, ... ... Weiner DB, et al. In vivo protection against ZIKV infection and pathogenesis through passive antibody transfer and active immunisation with a prMEnv DNA vaccine. Npj Vaccines. 1: 16021. PMID 29263859 DOI: 10.1038/npjvaccines.2016.21 |
0.78 |
|
| 2016 |
Morrow MP, Kraynyak KA, Sylvester AJ, Shen X, Amante D, Sakata L, Parker L, Yan J, Boyer J, Roh C, Humeau L, Khan AS, Broderick K, Marcozzi-Pierce K, Giffear M, ... ... Weiner DB, et al. Augmentation of cellular and humoral immune responses to HPV16 and HPV18 E6 and E7 antigens by VGX-3100. Molecular Therapy Oncolytics. 3: 16025. PMID 28054033 DOI: 10.1038/Mto.2016.25 |
0.743 |
|
| 2016 |
Griffiths KL, Villarreal DO, Weiner DB, Khader SA. A novel multivalent tuberculosis vaccine confers protection in a mouse model of tuberculosis. Human Vaccines & Immunotherapeutics. 0. PMID 27322875 DOI: 10.1080/21645515.2016.1197454 |
0.5 |
|
| 2016 |
Chung C, Ugen KE, Sardesai NY, Weiner DB, Muthumani K. Protocols for Developing Novel Chikungunya Virus DNA Vaccines. Methods in Molecular Biology (Clifton, N.J.). 1426: 311-32. PMID 27233283 DOI: 10.1007/978-1-4939-3618-2_28 |
0.492 |
|
| 2016 |
Chu JS, Villarreal DO, Weiner DB. DNA Vaccines: A Strategy for Developing Novel Multivalent TB Vaccines. Methods in Molecular Biology (Clifton, N.J.). 1403: 355-61. PMID 27076140 DOI: 10.1007/978-1-4939-3387-7_18 |
0.562 |
|
| 2016 |
Muthumani K, Block P, Flingai S, Muruganantham N, Chaaithanya IK, Tingey C, Wise M, Reuschel EL, Chung C, Muthumani A, Sarangan G, Srikanth P, Khan AS, Vijayachari P, Sardesai NY, ... ... Weiner DB, et al. Rapid and long-term immunity elicited by DNA encoded antibody prophylaxis and DNA vaccination against Chikungunya virus. The Journal of Infectious Diseases. PMID 27001960 DOI: 10.1093/Infdis/Jiw111 |
0.575 |
|
| 2016 |
Wise MC, Duperret EK, Villarreal DO, Louis L, Yan J, Morrow MP, Humeau LM, Sardesai NY, Weiner DB. Abstract A020: A novel synthetic CD40L plasmid adjuvant generates unique anti-HPV DNA vaccine induced responses that impact tumor growth Cancer Immunology Research. 4. DOI: 10.1158/2326-6066.Imm2016-A020 |
0.605 |
|
| 2016 |
Duperret E, Ammons D, Wise MC, Yan J, Humeau LM, Weiner DB. Abstract A010: A novel DNA vaccine targeting fibroblast activation protein (FAP) breaks tolerance and synergizes with anticancer immune therapy in mice Cancer Immunology Research. 4. DOI: 10.1158/2326-6066.Imm2016-A010 |
0.567 |
|
| 2016 |
Ferraro B, Walters JN, Reuschel EL, Balakrishnan A, Morrow MP, Khan AS, Sardesai NY, Humeau LM, Weiner DB. Abstract LB-253: Control of tumor growth in vivo by a synthetic multi-antigen DNA immune therapy for prostate cancer Cancer Research. 76. DOI: 10.1158/1538-7445.Am2016-Lb-253 |
0.519 |
|
| 2016 |
Elliott ST, Patel A, Fllingai S, Wise MC, Muthumani K, Weiner DB. 644. In Vivo Expression of Functional DNA Monoclonal Antibodies Targeting IL-6 and CD126 Molecular Therapy. 24: S255. DOI: 10.1016/S1525-0016(16)33452-9 |
0.382 |
|
| 2016 |
Wise M, Villarreal D, Louis L, Yan J, Morrow M, Sardesai N, Weiner D. 643. Various Forms of CD40L Encoded as an Immune Plasmid Adjuvant Generate Unique Anti-Cancer DNA Vaccine Induced Responses Molecular Therapy. 24: S255. DOI: 10.1016/S1525-0016(16)33451-7 |
0.627 |
|
| 2016 |
Morrow M, Trimble C, Shen X, Dallas M, Weiner D, Boyer J, Yan J, Kraynyak K, Sylester A, Giffear M, Marcozzi-Pierce K, Shah D, Broderick K, Khan A, Lee J, et al. 505. VGX-3100 Drives Regression of HPV16/18 CIN2/3 and Robust Cellular Immune Responses in Blood and Cervical Tissue in a Blinded, Randomized, Placebo-Controlled Phase 2B Study Molecular Therapy. 24: S201. DOI: 10.1016/S1525-0016(16)33314-7 |
0.71 |
|
| 2016 |
Patel A, Reuschel EL, Kraynyak KA, Racine T, Park DH, Keaton AA, Karuppiah M, Shedlock D, Yan J, Khan A, Tierney K, Sardesai N, Kobinger GP, Weiner DB. 479. An Optimized DNA Vaccine Formulation Protects Against Lethal Ebola Makona Virus Challenge in Non-Human Primates and Elicits Robust Immune Responses Molecular Therapy. 24: S189-S190. DOI: 10.1016/S1525-0016(16)33288-9 |
0.804 |
|
| 2016 |
Wise M, Muthumani K, Mendoza J, Yan J, Slager A, Kraynyak K, Montefiori D, LaBranche C, Broderick K, Morrow M, Sardesai N, Weiner D. 440. Extreme Polyvalency Induces Potent Cross-Clade Cellular and Humoral Responses in Rabbits and Non-Human Primates Molecular Therapy. 24: S174. DOI: 10.1016/S1525-0016(16)33249-X |
0.577 |
|
| 2016 |
Reuschel EL, Muthumani K, Kraynyak K, Tingey C, Kudchodkar SB, Khan AS, Sardesai NY, Kim JJ, Maslow J, Park YK, Kobinger G, Falzarano D, Feldman H, Weiner DB. 436. Developing a Synthetic DNA Vaccine for an Emerging Pathogen - Middle East Respiratory Syndrome Molecular Therapy. 24: S172-S173. DOI: 10.1016/S1525-0016(16)33245-2 |
0.615 |
|
| 2016 |
Elliott ST, Patel A, Wise MC, Flingai S, Keaton A, Yan J, Broderick KE, Smith T, Sardesai NY, Muthumani K, Weiner DB. 433. DNA Monoclonal Antibodies Target Influenza Virus In Vivo Molecular Therapy. 24: S171-S172. DOI: 10.1016/S1525-0016(16)33242-7 |
0.435 |
|
| 2016 |
Flingai S, Plummer E, Patel A, Mendoza J, Wang Y, Riemann K, Klempner M, Broderick K, Sardesai N, Muthumani K, Weiner D. 428. Generation of DNA Plasmid-Encoded Neutralizing Monoclonal Antibodies In Vivo Molecular Therapy. 24: S169-S170. DOI: 10.1016/S1525-0016(16)33237-3 |
0.365 |
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| 2016 |
Muthumani K, Chung C, Agarwal S, Plyler R, Kudchodkar S, Flingai S, Ugen K, Kim J, Sardesai N, Weiner DB. 401. In Vivo Expression of Plasmid Encoded IgG for PD-1 or LAG3 by Synthetic DNA as a New Tool for Cancer Immunotherapy Molecular Therapy. 24: S159. DOI: 10.1016/S1525-0016(16)33210-5 |
0.468 |
|
| 2016 |
Patel A, Flingai S, Elliott ST, Smith T, Wise MC, Ramos S, Yan J, Schultheis K, Keaton AA, Park DH, Broderick KE, Sardesai N, Karuppiah M, Weiner DB. 264. In Vivo DNA-Monoclonal Antibody (DMAb) Gene Delivery Protects Against Lethal Bacterial and Viral Challenges in Mice Molecular Therapy. 24: S105. DOI: 10.1016/S1525-0016(16)33073-8 |
0.382 |
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| 2016 |
Muthumani K, Block P, Flingai S, Muruganantham N, Chaaithanya I, Sarangan G, Srikanth P, Vijayachari P, Sardesai N, Kim J, Ugen K, Weiner D. Synthetic DNA encoded antibody prophylaxis confers rapid protective immunity in vivo against Chikungunya virus infection International Journal of Infectious Diseases. 45: 185. DOI: 10.1016/J.Ijid.2016.02.432 |
0.461 |
|
| 2015 |
Trimble CL, Morrow MP, Kraynyak KA, Shen X, Dallas M, Yan J, Edwards L, Parker RL, Denny L, Giffear M, Brown AS, Marcozzi-Pierce K, Shah D, Slager AM, Sylvester AJ, ... ... Weiner DB, et al. Safety, efficacy, and immunogenicity of VGX-3100, a therapeutic synthetic DNA vaccine targeting human papillomavirus 16 and 18 E6 and E7 proteins for cervical intraepithelial neoplasia 2/3: a randomised, double-blind, placebo-controlled phase 2b trial. Lancet (London, England). PMID 26386540 DOI: 10.1016/S0140-6736(15)00239-1 |
0.712 |
|
| 2015 |
Reuschel EL, Wang J, Shivers DK, Muthumani K, Weiner DB, Ma Z, Finkel TH. REDD1 Is Essential for Optimal T Cell Proliferation and Survival. Plos One. 10: e0136323. PMID 26301899 DOI: 10.1371/Journal.Pone.0136323 |
0.324 |
|
| 2015 |
Muthumani K, Falzarano D, Reuschel EL, Tingey C, Flingai S, Villarreal DO, Wise M, Patel A, Izmirly A, Aljuaid A, Seliga AM, Soule G, Morrow M, Kraynyak KA, Khan AS, ... ... Weiner DB, et al. A synthetic consensus anti-spike protein DNA vaccine induces protective immunity against Middle East respiratory syndrome coronavirus in nonhuman primates. Science Translational Medicine. 7: 301ra132. PMID 26290414 DOI: 10.1016/J.Ijid.2016.02.083 |
0.799 |
|
| 2015 |
Flingai S, Plummer EM, Patel A, Shresta S, Mendoza JM, Broderick KE, Sardesai NY, Muthumani K, Weiner DB. Protection against dengue disease by synthetic nucleic acid antibody prophylaxis/immunotherapy. Scientific Reports. 5: 12616. PMID 26220099 DOI: 10.1038/Srep12616 |
0.402 |
|
| 2015 |
Ugen KE, Weiner DB. DNA vaccines 2014 meeting: Highlights and overview. Human Vaccines & Immunotherapeutics. 11: 1887-8. PMID 26158530 DOI: 10.1080/21645515.2015.1066947 |
0.607 |
|
| 2015 |
Scott VL, Villarreal DO, Hutnick NA, Walters JN, Ragwan E, Bdeir K, Yan J, Sardesai NY, Finnefrock AC, Casimiro DR, Weiner DB. DNA vaccines targeting heavy chain C-terminal fragments of Clostridium botulinum neurotoxin serotypes A, B, and E induce potent humoral and cellular immunity and provide protection from lethal toxin challenge. Human Vaccines & Immunotherapeutics. 11: 1961-71. PMID 26158319 DOI: 10.1080/21645515.2015.1066051 |
0.588 |
|
| 2015 |
Villarreal DO, Wise MC, Siefert RJ, Yan J, Wood LM, Weiner DB. Ubiquitin-like molecule ISG15 acts as an immune adjuvant to enhance antigen-specific CD8 T cell tumor immunity. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 26122932 DOI: 10.1038/Mt.2015.120 |
0.543 |
|
| 2015 |
Scott VL, Patel A, Villarreal DO, Hensley SE, Ragwan E, Yan J, Sardesai NY, Rothwell PJ, Extance JP, Caproni LJ, Weiner DB. Novel synthetic plasmid and doggybone™ DNA vaccines induce neutralizing antibodies and provide protection from lethal influenza challenge in mice. Human Vaccines & Immunotherapeutics. 0. PMID 26091432 DOI: 10.1080/21645515.2015.1022008 |
0.579 |
|
| 2015 |
Villarreal DO, Siefert RJ, Weiner DB. Alarmin IL-33 elicits potent TB-specific cell-mediated responses. Human Vaccines & Immunotherapeutics. 11: 1954-60. PMID 26091147 DOI: 10.1080/21645515.2015.1026499 |
0.53 |
|
| 2015 |
Wise MC, Hutnick NA, Pollara J, Myles DJ, Williams C, Yan J, LaBranche CC, Khan AS, Sardesai NY, Montefiori D, Barnett SW, Zolla-Pazner S, Ferrari G, Weiner DB. An enhanced synthetic multi-clade DNA prime induces improved cross-clade reactive functional antibodies when combined with an adjuvanted protein boost in non-human primates. Journal of Virology. PMID 26085155 DOI: 10.1128/Jvi.00652-15 |
0.594 |
|
| 2015 |
Vijayachari P, Vedhagiri K, Mallilankaraman K, Mathur PP, Sardesai NY, Weiner DB, Ugen KE, Muthumani K. Immunogenicity of a novel enhanced consensus DNA vaccine encoding the leptospiral protein LipL45. Human Vaccines & Immunotherapeutics. 11: 1945-53. PMID 26020621 DOI: 10.1080/21645515.2015.1047117 |
0.597 |
|
| 2015 |
Kutzler MA, Wise MC, Hutnick NA, Moldoveanu Z, Hunter M, Reuter MA, Yuan S, Yan J, Ginsberg AA, Sylvester A, Pahar B, Carnathan DG, Kathuria N, Khan AS, Montefiori D, ... ... Weiner DB, et al. Chemokine-adjuvanted electroporated DNA vaccine induces substantial protection from simian immunodeficiency virus vaginal challenge. Mucosal Immunology. PMID 25943275 DOI: 10.1038/Mi.2015.31 |
0.616 |
|
| 2015 |
Villarreal DO, Svoronos N, Wise MC, Shedlock DJ, Morrow MP, Conejo-Garcia JR, Weiner DB. Molecular adjuvant IL-33 enhances the potency of a DNA vaccine in a lethal challenge model. Vaccine. PMID 25887087 DOI: 10.1016/J.Vaccine.2015.03.086 |
0.53 |
|
| 2015 |
Wu SJ, Villarreal DO, Shedlock DJ, Weiner DB. Synthetic DNA approach to cytomegalovirus vaccine/immune therapy. Advances in Experimental Medicine and Biology. 848: 131-48. PMID 25757619 DOI: 10.1007/978-1-4939-2432-5_7 |
0.5 |
|
| 2015 |
Villarreal DO, Weiner DB. IL-33 isoforms: their future as vaccine adjuvants? Expert Review of Vaccines. 14: 489-92. PMID 25656504 DOI: 10.1586/14760584.2015.1011135 |
0.469 |
|
| 2015 |
Carnathan DG, Wetzel KS, Yu J, Lee ST, Johnson BA, Paiardini M, Yan J, Morrow MP, Sardesai NY, Weiner DB, Ertl HC, Silvestri G. Activated CD4+CCR5+ T cells in the rectum predict increased SIV acquisition in SIVGag/Tat-vaccinated rhesus macaques. Proceedings of the National Academy of Sciences of the United States of America. 112: 518-23. PMID 25550504 DOI: 10.1073/Pnas.1407466112 |
0.541 |
|
| 2015 |
Morrow MP, Tebas P, Yan J, Ramirez L, Slager A, Kraynyak K, Diehl M, Shah D, Khan A, Lee J, Boyer J, Kim JJ, Sardesai NY, Weiner DB, Bagarazzi ML. Synthetic consensus HIV-1 DNA induces potent cellular immune responses and synthesis of granzyme B, perforin in HIV infected individuals. Molecular Therapy : the Journal of the American Society of Gene Therapy. 23: 591-601. PMID 25531694 DOI: 10.1038/Mt.2014.245 |
0.722 |
|
| 2015 |
Vonderheide RH, Aggarwal C, Bajor DL, Goldenberg J, Loch C, Lee JC, Yan J, Morrow MP, DeMichele A, Langer CJ, O'Dwyer PJ, Weiner DB, Yang Z, Bagarazzi ML. Study of hTERT and IL-12 DNA immunotherapy using electroporation in patients with solid tumors after definitive surgery and adjuvant therapy. Journal of Clinical Oncology. 33: TPS3104-TPS3104. DOI: 10.1200/Jco.2015.33.15_Suppl.Tps3104 |
0.472 |
|
| 2015 |
Aggarwal C, Cohen R, Morrow MP, Bauml J, Weinstein G, Boyer J, Shen X, Yan J, Goldenberg J, Nashit D, Oyola S, Lee J, Humeau LM, Weiner DB, Yang Z, ... ... Weiner D, et al. Immunotherapy with VGX-3100 (HPV16 and HPV18 plasmids) + INO-9012 (DNA encoding IL-12) in human papillomavirus (HPV) associated head and neck squamous cell carcinoma (HNSCCa): interim safety and immunogenicity results Journal For Immunotherapy of Cancer. 3. DOI: 10.1186/2051-1426-3-S2-P426 |
0.309 |
|
| 2015 |
Morrow M, Trimble C, Shen X, Dallas M, Weiner D, Boyer J, Yan J, Kraynyak K, Sylvester A, Giffear M, Marcozzi-Pierce K, Shah D, Broderick K, Khan A, Lee J, et al. Abstract CT131: HPV specific immunotherapy for cervical intraepithelial neoplasia using VGX-3100 induces regression of cervical lesions and potent T-cell responses: Results from a randomized, double-blind, placebo-controlled phase II study Cancer Research. 75. DOI: 10.1158/1538-7445.Am2015-Ct131 |
0.709 |
|
| 2015 |
Flingai SF, Plummer EM, Patel A, Shresta S, Mendoza JM, Broderick KE, Sardesai NY, Muthumani K, Weiner DB. 453. Protection Against Lethal Dengue Challenge By IM Delivery of Synthetic, EP-Delivered DNA Encoding Designed Anti-Dengue Neutralizing Antibodies Molecular Therapy. 23: S180. DOI: 10.1016/S1525-0016(16)34062-X |
0.389 |
|
| 2015 |
Patel A, Reuschel EL, Scott VL, Kraynyak KA, Wong G, Villarreal DO, Karuppiah M, Shedlock D, Yan J, Broderick KE, Khan A, Tierney K, Kobinger GP, Sardesai N, Weiner DB. 450. A Single Immunization With Optimized DNA Vaccines Protects Against Lethal Ebola Virus Challenge in Mice and Induces Seroconversion in Non-Human Primates Following a DNA Prime–DNA Boost Approach Molecular Therapy. 23: S178-S179. DOI: 10.1016/S1525-0016(16)34059-X |
0.819 |
|
| 2015 |
Yan J, Chu JS, Obeng-Adjei N, Morrow MP, Kraynyak K, Slager AM, Yang M, Khan AS, Broderick KE, Sardesai NY, Weiner DB. 417. Induction of Potent Cytotoxic and Antitumor Activity By a Highly Optimized hTERT DNA Vaccine Molecular Therapy. 23: S165. DOI: 10.1016/S1525-0016(16)34026-6 |
0.856 |
|
| 2015 |
Yan J, Choi M, Chu JS, Villarreal DO, Morrow MP, Yang M, Khan AS, Broderick KE, Sardesai NY, Weiner DB. 218. Enhanced Antitumor Immunity Induced By HPV16 and 18 E6/E7 DNA Vaccine in Combination with IL-12 as an Immuno-Adjuvant Molecular Therapy. 23: S85-S86. DOI: 10.1016/S1525-0016(16)33823-0 |
0.527 |
|
| 2015 |
Ferraro B, Walters JN, Reuschel EL, Balakrishnan A, Morrow MP, Yan J, Khan AS, Sardesai NY, Humeau LM, Weiner DB. 210. Complete Control of Tumor Growth In Vivo By a Synthetic Consensus Multi-Antigen DNA Immune Therapy for Prostate Cancer Molecular Therapy. 23: S83. DOI: 10.1016/S1525-0016(16)33815-1 |
0.535 |
|
| 2014 |
Shedlock DJ, Tingey C, Mahadevan L, Hutnick N, Reuschel EL, Kudchodkar S, Flingai S, Yan J, Kim JJ, Ugen KE, Weiner DB, Muthumani K. Co-Administration of Molecular Adjuvants Expressing NF-Kappa B Subunit p65/RelA or Type-1 Transactivator T-bet Enhance Antigen Specific DNA Vaccine-Induced Immunity. Vaccines. 2: 196-215. PMID 26344618 DOI: 10.3390/Vaccines2020196 |
0.612 |
|
| 2014 |
Latimer B, Toporovski R, Yan J, Pankhong P, Morrow MP, Khan AS, Sardesai NY, Welles SL, Jacobson JM, Weiner DB, Kutzler MA. Strong HCV NS3/4a, NS4b, NS5a, NS5b-specific cellular immune responses induced in Rhesus macaques by a novel HCV genotype 1a/1b consensus DNA vaccine. Human Vaccines & Immunotherapeutics. 10: 2357-65. PMID 25424943 DOI: 10.4161/Hv.29590 |
0.493 |
|
| 2014 |
Villarreal DO, Walters J, Laddy DJ, Yan J, Weiner DB. Multivalent TB vaccines targeting the esx gene family generate potent and broad cell-mediated immune responses superior to BCG. Human Vaccines & Immunotherapeutics. 10: 2188-98. PMID 25424922 DOI: 10.4161/Hv.29574 |
0.828 |
|
| 2014 |
Yan J, Tingey C, Lyde R, Gorham TC, Choo DK, Muthumani A, Myles D, Weiner LP, Kraynyak KA, Reuschel EL, Finkel TH, Kim JJ, Sardesai NY, Ugen KE, Muthumani K, ... Weiner DB, et al. Novel and enhanced anti-melanoma DNA vaccine targeting the tyrosinase protein inhibits myeloid-derived suppressor cells and tumor growth in a syngeneic prophylactic and therapeutic murine model. Cancer Gene Therapy. 21: 507-17. PMID 25394503 DOI: 10.1038/Cgt.2014.56 |
0.779 |
|
| 2014 |
Choi JH, Jonsson-Schmunk K, Qiu X, Shedlock DJ, Strong J, Xu JX, Michie KL, Audet J, Fernando L, Myers MJ, Weiner D, Bajrovic I, Tran LQ, Wong G, Bello A, et al. A Single Dose Respiratory Recombinant Adenovirus-Based Vaccine Provides Long-Term Protection for Non-Human Primates from Lethal Ebola Infection. Molecular Pharmaceutics. PMID 25363619 DOI: 10.1021/Mp500646D |
0.562 |
|
| 2014 |
Baliban SM, Michael A, Shammassian B, Mudakha S, Khan AS, Cocklin S, Zentner I, Latimer BP, Bouillaut L, Hunter M, Marx P, Sardesai NY, Welles SL, Jacobson JM, Weiner DB, et al. An optimized, synthetic DNA vaccine encoding the toxin A and toxin B receptor binding domains of Clostridium difficile induces protective antibody responses in vivo. Infection and Immunity. 82: 4080-91. PMID 25024365 DOI: 10.1128/Iai.01950-14 |
0.562 |
|
| 2014 |
Villarreal DO, Weiner DB. Interleukin 33: a switch-hitting cytokine. Current Opinion in Immunology. 28: 102-6. PMID 24762410 DOI: 10.1016/J.Coi.2014.03.004 |
0.434 |
|
| 2014 |
Yan J, Villarreal DO, Racine T, Chu JS, Walters JN, Morrow MP, Khan AS, Sardesai NY, Kim JJ, Kobinger GP, Weiner DB. Protective immunity to H7N9 influenza viruses elicited by synthetic DNA vaccine. Vaccine. 32: 2833-42. PMID 24631084 DOI: 10.1016/J.Vaccine.2014.02.038 |
0.536 |
|
| 2014 |
Weiner DB, Buckland B. Vaccine Technology IV: an ECI Conference held in Albufeira, Portugal from May 20 to 24, 2012. Vaccine. 32: 2763-6. PMID 24583001 DOI: 10.1016/J.Vaccine.2014.02.015 |
0.443 |
|
| 2014 |
Fagone P, Muthumani K, Mangano K, Magro G, Meroni PL, Kim JJ, Sardesai NY, Weiner DB, Nicoletti F. VGX-1027 modulates genes involved in lipopolysaccharide-induced Toll-like receptor 4 activation and in a murine model of systemic lupus erythematosus. Immunology. 142: 594-602. PMID 24527796 DOI: 10.1111/Imm.12267 |
0.382 |
|
| 2014 |
Villarreal DO, Wise MC, Walters JN, Reuschel EL, Choi MJ, Obeng-Adjei N, Yan J, Morrow MP, Weiner DB. Alarmin IL-33 acts as an immunoadjuvant to enhance antigen-specific tumor immunity. Cancer Research. 74: 1789-800. PMID 24448242 DOI: 10.1158/0008-5472.Can-13-2729 |
0.839 |
|
| 2014 |
Morrow MP, Kraynyak K, Shen X, Knott C, Yan J, Broderick K, Khan A, Giffear M, Lee J, Boyer J, Weiner D, Sardesai N, Bagarazzi M. Boosting of cellular and humoral immune responses to HPV16/18 antigens by VGX-3100: A follow-on phase I trial. Journal of Clinical Oncology. 32: 3101-3101. DOI: 10.1200/Jco.2014.32.15_Suppl.3101 |
0.731 |
|
| 2014 |
Villarreal D, Wise M, Walters J, Yan J, Morrow MP, Bagarazzi M, Sardesai N, Weiner D. Synthetic IL-33 DNA as anti-tumor adjuvant in vivo. Journal of Clinical Oncology. 32: 3098-3098. DOI: 10.1200/Jco.2014.32.15_Suppl.3098 |
0.461 |
|
| 2014 |
Humeau L, Trimble C, Morrow M, Shen X, Dallas M, Weiner D, Boyer J, Yan J, Kraynyak K, Sylvester A, Giffear M, Marcozzi-Pierce K, Shah D, Broderick K, Khan A, et al. DNA vaccine VGX-3100 with electroporation induces regression of cervical intraepithelial neoplasia 2/3 and clears HPV infection with robust T cell responses: results of a randomized, double-blind, placebo-controlled Phase II trial Journal For Immunotherapy of Cancer. 2: 1-1. DOI: 10.1186/2051-1426-2-S3-O17 |
0.719 |
|
| 2014 |
Villarreal D, Wise MC, Yang J, Weiner DB. Abstract LB-257: Immunoadjuvant ISG15 enhances human papillomavirus 16 antigen-specific cell-mediated antitumor immunity Cancer Research. 74. DOI: 10.1158/1538-7445.Am2014-Lb-257 |
0.539 |
|
| 2014 |
Villarreal DO, Svoronos N, Wise MC, Walters JN, Morrow M, Weiner DB. 192 Cytokine. 70: 74. DOI: 10.1016/J.Cyto.2014.07.199 |
0.541 |
|
| 2013 |
Yan J, Pankhong P, Shin TH, Obeng-Adjei N, Morrow MP, Walters JN, Khan AS, Sardesai NY, Weiner DB. Highly optimized DNA vaccine targeting human telomerase reverse transcriptase stimulates potent antitumor immunity. Cancer Immunology Research. 1: 179-89. PMID 24777680 DOI: 10.1158/2326-6066.Cir-13-0001 |
0.858 |
|
| 2013 |
Muthumani K, Wise MC, Broderick KE, Hutnick N, Goodman J, Flingai S, Yan J, Bian CB, Mendoza J, Tingey C, Wilson C, Wojtak K, Sardesai NY, Weiner DB. HIV-1 Env DNA vaccine plus protein boost delivered by EP expands B- and T-cell responses and neutralizing phenotype in vivo. Plos One. 8: e84234. PMID 24391921 DOI: 10.1371/Journal.Pone.0084234 |
0.544 |
|
| 2013 |
Obeng-Adjei N, Hutnick NA, Yan J, Chu JS, Myles DJ, Morrow MP, Sardesai NY, Weiner DB. DNA vaccine cocktail expressing genotype A and C HBV surface and consensus core antigens generates robust cytotoxic and antibody responses in mice and Rhesus macaques. Cancer Gene Therapy. 20: 652-62. PMID 24310062 DOI: 10.1038/Cgt.2013.65 |
0.854 |
|
| 2013 |
Flingai S, Czerwonko M, Goodman J, Kudchodkar SB, Muthumani K, Weiner DB. Synthetic DNA vaccines: improved vaccine potency by electroporation and co-delivered genetic adjuvants. Frontiers in Immunology. 4: 354. PMID 24204366 DOI: 10.3389/Fimmu.2013.00354 |
0.575 |
|
| 2013 |
Ugen K, Weiner DB. DNA vaccines onward and upward! 20 years and counting! Highlights of the DNA vaccines 2012 meeting. Human Vaccines & Immunotherapeutics. 9: 2038-40. PMID 24131943 DOI: 10.4161/Hv.26628 |
0.517 |
|
| 2013 |
Muthumani K, Flingai S, Wise M, Tingey C, Ugen KE, Weiner DB. Optimized and enhanced DNA plasmid vector based in vivo construction of a neutralizing anti-HIV-1 envelope glycoprotein Fab. Human Vaccines & Immunotherapeutics. 9: 2253-62. PMID 24045230 DOI: 10.4161/Hv.26498 |
0.418 |
|
| 2013 |
Obeng-Adjei N, Choo DK, Weiner DB. Hydrodynamic immunization leads to poor CD8 T-cell expansion, low frequency of memory CTLs and ineffective antiviral protection. Cancer Gene Therapy. 20: 552-63. PMID 23969886 DOI: 10.1038/Cgt.2013.52 |
0.803 |
|
| 2013 |
Ferraro B, Talbott KT, Balakrishnan A, Cisper N, Morrow MP, Hutnick NA, Myles DJ, Shedlock DJ, Obeng-Adjei N, Yan J, Kayatani AK, Richie N, Cabrera W, Shiver R, Khan AS, ... ... Weiner DB, et al. Inducing humoral and cellular responses to multiple sporozoite and liver-stage malaria antigens using exogenous plasmid DNA. Infection and Immunity. 81: 3709-20. PMID 23897618 DOI: 10.1128/Iai.00180-13 |
0.849 |
|
| 2013 |
Kalams SA, Parker SD, Elizaga M, Metch B, Edupuganti S, Hural J, De Rosa S, Carter DK, Rybczyk K, Frank I, Fuchs J, Koblin B, Kim DH, Joseph P, Keefer MC, ... ... Weiner DB, et al. Safety and comparative immunogenicity of an HIV-1 DNA vaccine in combination with plasmid interleukin 12 and impact of intramuscular electroporation for delivery. The Journal of Infectious Diseases. 208: 818-29. PMID 23840043 DOI: 10.1093/Infdis/Jit236 |
0.595 |
|
| 2013 |
Shedlock DJ, Aviles J, Talbott KT, Wong G, Wu SJ, Villarreal DO, Myles DJ, Croyle MA, Yan J, Kobinger GP, Weiner DB. Induction of broad cytotoxic T cells by protective DNA vaccination against Marburg and Ebola. Molecular Therapy : the Journal of the American Society of Gene Therapy. 21: 1432-44. PMID 23670573 DOI: 10.1038/Mt.2013.61 |
0.574 |
|
| 2013 |
Villarreal DO, Talbott KT, Choo DK, Shedlock DJ, Weiner DB. Synthetic DNA vaccine strategies against persistent viral infections. Expert Review of Vaccines. 12: 537-54. PMID 23659301 DOI: 10.1586/Erv.13.33 |
0.578 |
|
| 2013 |
Kulkarni V, Rosati M, Valentin A, Ganneru B, Singh AK, Yan J, Rolland M, Alicea C, Beach RK, Zhang GM, Le Gall S, Broderick KE, Sardesai NY, Heckerman D, Mothe B, ... ... Weiner DB, et al. HIV-1 p24(gag) derived conserved element DNA vaccine increases the breadth of immune response in mice. Plos One. 8: e60245. PMID 23555935 DOI: 10.1371/Journal.Pone.0060245 |
0.581 |
|
| 2013 |
Weiner DB. RNA-based vaccination: sending a strong message. Molecular Therapy : the Journal of the American Society of Gene Therapy. 21: 506-8. PMID 23449108 DOI: 10.1038/Mt.2013.26 |
0.531 |
|
| 2013 |
Bao H, Ramanathan AA, Kawalakar O, Sundaram SG, Tingey C, Bian CB, Muruganandam N, Vijayachari P, Sardesai NY, Weiner DB, Ugen KE, Muthumani K. Nonstructural protein 2 (nsP2) of Chikungunya virus (CHIKV) enhances protective immunity mediated by a CHIKV envelope protein expressing DNA Vaccine. Viral Immunology. 26: 75-83. PMID 23409931 DOI: 10.1089/Vim.2012.0061 |
0.596 |
|
| 2012 |
Lang Kuhs KA, Ginsberg AA, Yan J, Wiseman RW, Khan AS, Sardesai NY, O'Connor DH, Weiner DB. Hepatitis C Virus NS3/NS4A DNA Vaccine Induces Multiepitope T Cell Responses in Rhesus Macaques Mimicking Human Immune Responses. Molecular Therapy : the Journal of the American Society of Gene Therapy. 20: 669-678. PMID 28160634 DOI: 10.1038/mt.2011.188 |
0.413 |
|
| 2012 |
Lang Kuhs KA, Toporovski R, Yan J, Ginsberg AA, Shedlock DJ, Weiner DB. Induction of intrahepatic HCV NS4B, NS5A and NS5B-specific cellular immune responses following peripheral immunization. Plos One. 7: e52165. PMID 23284919 DOI: 10.1371/Journal.Pone.0052165 |
0.405 |
|
| 2012 |
Kathuria N, Kraynyak KA, Carnathan D, Betts M, Weiner DB, Kutzler MA. Generation of antigen-specific immunity following systemic immunization with DNA vaccine encoding CCL25 chemokine immunoadjuvant. Human Vaccines & Immunotherapeutics. 8: 1607-19. PMID 23151454 DOI: 10.4161/Hv.22574 |
0.82 |
|
| 2012 |
Shedlock DJ, Talbott KT, Wu SJ, Wilson CM, Muthumani K, Boyer JD, Sardesai NY, Awasthi S, Weiner DB. Vaccination with synthetic constructs expressing cytomegalovirus immunogens is highly T cell immunogenic in mice. Human Vaccines & Immunotherapeutics. 8: 1668-81. PMID 23151448 DOI: 10.4161/Hv.22447 |
0.555 |
|
| 2012 |
Reuter MA, Yuan S, Marx PA, Kutzler MA, Weiner DB, Betts MR. DNA-based HIV vaccines do not induce generalized activation in mucosal tissue T cells. Human Vaccines & Immunotherapeutics. 8: 1648-53. PMID 23111167 DOI: 10.4161/Hv.22247 |
0.546 |
|
| 2012 |
Bagarazzi ML, Yan J, Morrow MP, Shen X, Parker RL, Lee JC, Giffear M, Pankhong P, Khan AS, Broderick KE, Knott C, Lin F, Boyer JD, Draghia-Akli R, White CJ, ... ... Weiner DB, et al. Immunotherapy against HPV16/18 generates potent TH1 and cytotoxic cellular immune responses. Science Translational Medicine. 4: 155ra138. PMID 23052295 DOI: 10.1126/Scitranslmed.3004414 |
0.392 |
|
| 2012 |
Obeng-Adjei N, Choo DK, Saini J, Yan J, Pankhong P, Parikh A, Chu JS, Weiner DB. Synthetic DNA immunogen encoding hepatitis B core antigen drives immune response in liver. Cancer Gene Therapy. 19: 779-87. PMID 23037809 DOI: 10.1038/Cgt.2012.61 |
0.842 |
|
| 2012 |
Sonnenberg GF, Monticelli LA, Alenghat T, Fung TC, Hutnick NA, Kunisawa J, Shibata N, Grunberg S, Sinha R, Zahm AM, Tardif MR, Sathaliyawala T, Kubota M, Farber DL, Collman RG, ... ... Weiner DB, et al. Innate lymphoid cells promote anatomical containment of lymphoid-resident commensal bacteria. Science (New York, N.Y.). 336: 1321-5. PMID 22674331 DOI: 10.1126/Science.1222551 |
0.333 |
|
| 2012 |
Hutnick NA, Myles DJ, Ferraro B, Lucke C, Lin F, Yan J, Broderick KE, Khan AS, Sardesai NY, Weiner DB. Intradermal DNA vaccination enhanced by low-current electroporation improves antigen expression and induces robust cellular and humoral immune responses. Human Gene Therapy. 23: 943-50. PMID 22650607 DOI: 10.1089/Hum.2012.055 |
0.596 |
|
| 2012 |
Feng C, Jin J, Zou Q, Chen X, Zhou C, Wu B, Weiner DB, Wang B. Interleukin-21 inhibits humoral response to an HIV DNA vaccine by enhancing Bcl-6 and Pax-5 expression. Viral Immunology. 25: 131-40. PMID 22486304 DOI: 10.1089/Vim.2011.0073 |
0.555 |
|
| 2012 |
Hutnick NA, Myles DJ, Hirao L, Scott VL, Ferraro B, Khan AS, Lewis MG, Miller CJ, Bett AJ, Casimiro D, Sardesai NY, Kim JJ, Shiver J, Weiner DB. An optimized SIV DNA vaccine can serve as a boost for Ad5 and provide partial protection from a high-dose SIVmac251 challenge. Vaccine. 30: 3202-8. PMID 22406458 DOI: 10.1016/J.Vaccine.2012.02.069 |
0.823 |
|
| 2012 |
Shin TH, Pankhong P, Yan J, Khan AS, Sardesai NY, Weiner DB. Induction of robust cellular immunity against HPV6 and HPV11 in mice by DNA vaccine encoding for E6/E7 antigen. Human Vaccines & Immunotherapeutics. 8: 470-8. PMID 22336879 DOI: 10.4161/Hv.19180 |
0.426 |
|
| 2012 |
Kalams SA, Parker S, Jin X, Elizaga M, Metch B, Wang M, Hural J, Lubeck M, Eldridge J, Cardinali M, Blattner WA, Sobieszczyk M, Suriyanon V, Kalichman A, Weiner DB, et al. Safety and immunogenicity of an HIV-1 gag DNA vaccine with or without IL-12 and/or IL-15 plasmid cytokine adjuvant in healthy, HIV-1 uninfected adults. Plos One. 7: e29231. PMID 22242162 DOI: 10.1371/Journal.Pone.0029231 |
0.527 |
|
| 2012 |
Mothe B, Llano A, Ibarrondo J, Zamarreño J, Schiaulini M, Miranda C, Ruiz-Riol M, Berger CT, Herrero MJ, Palou E, Plana M, Rolland M, Khatri A, Heckerman D, Pereyra F, ... ... Weiner D, et al. CTL responses of high functional avidity and broad variant cross-reactivity are associated with HIV control. Plos One. 7: e29717. PMID 22238642 DOI: 10.1371/Journal.Pone.0029717 |
0.412 |
|
| 2012 |
Cox JH, Ferrari MG, Earl P, Lane JR, Jagodzinski LL, Polonis VR, Kuta EG, Boyer JD, Ratto-Kim S, Eller LA, Pham DT, Hart L, Montefiori D, Ferrari G, Parrish S, ... Weiner DB, et al. Inclusion of a CRF01_AE HIV envelope protein boost with a DNA/MVA prime-boost vaccine: Impact on humoral and cellular immunogenicity and viral load reduction after SHIV-E challenge. Vaccine. 30: 1830-40. PMID 22234262 DOI: 10.1016/J.Vaccine.2011.12.131 |
0.54 |
|
| 2012 |
Lang Kuhs KA, Ginsberg AA, Yan J, Wiseman RW, Khan AS, Sardesai NY, O'Connor DH, Weiner DB. Hepatitis C virus NS3/NS4A DNA vaccine induces multiepitope T cell responses in rhesus macaques mimicking human immune responses [corrected]. Molecular Therapy : the Journal of the American Society of Gene Therapy. 20: 669-78. PMID 21952169 DOI: 10.1038/Mt.2011.188 |
0.51 |
|
| 2012 |
Ugen KE, Weiner DB. Highlights of the DNA Vaccines 2011 Meeting Human Vaccines and Immunotherapeutics. 8: 1554. DOI: 10.4161/Hv.22752 |
0.565 |
|
| 2012 |
Hutnick N, Karuppiah M, Pollara J, Yan J, Myles D, Broderick K, Morrow M, Sardasai N, Montefiori D, Barnett S, Ferrari G, Weiner D. E-DNA IM or ID delivery prime enhances antibody and T cell responses following recombinant gp120 env boost Retrovirology. 9: 364. DOI: 10.1186/1742-4690-9-S2-P364 |
0.605 |
|
| 2012 |
Yan J, Pankhong P, Khan A, Sardesai N, Weiner D. Comparison of cellular and humoral immune responses induced by primary, consensus or mosaic HIV-1 Env DNA vaccines Retrovirology. 9: 333. DOI: 10.1186/1742-4690-9-S2-P333 |
0.582 |
|
| 2012 |
Tebas P, Ramirez L, Morrow M, Yan J, Shah D, Lee J, Weiner D, Boyer J, Bagarazzi M, Sardesai N. Potent cellular immune responses after therapeutic immunization of HIV-positive patients with the PENNVAX®-B DNA vaccine in a Phase I Trial. Retrovirology. 9: 276. DOI: 10.1186/1742-4690-9-S2-P276 |
0.457 |
|
| 2012 |
Hutnick N, Myles D, Ginsberg A, Khan A, Yan J, Moldoveanu Z, Mestecky J, Marx P, Kutzler M, Weiner D. Improved systemic and mucosal antibody responses with a CCR10 ligand adjuvant Retrovirology. 9: 203. DOI: 10.1186/1742-4690-9-S2-P203 |
0.558 |
|
| 2012 |
Hutnick N, Myles D, Muthumani K, Morrow M, Yan J, Khan A, Sardasai N, Weiner D. Robust antibody and cellular responses with an improved DNA vaccine alone Retrovirology. 9: 15. DOI: 10.1186/1742-4690-9-S2-P15 |
0.597 |
|
| 2012 |
Sardesai N, Khan A, McCoy J, Lin F, Mendoza J, Yang M, Yan J, Hutnick N, Muthumani K, Weiner D, Broderick K. Minimally invasive and surface electroporation delivery of DNA vaccines for the induction of robust humoral immune responses against HIV antigens Retrovirology. 9: 1-1. DOI: 10.1186/1742-4690-9-S2-O9 |
0.595 |
|
| 2012 |
Pavlakis G, Kulkarni V, Valentin A, Rosati M, Sardesai N, Mothe B, Brander C, LeGall S, Weiner D, Rolland M, Mullins J, Felber B. DNA vaccines expressing conserved elements provide potent and broad immune responses Retrovirology. 9: 1-1. DOI: 10.1186/1742-4690-9-S2-O67 |
0.568 |
|
| 2012 |
Ginsberg AA, Shen X, Hutnick NA, Weiner DB. Improvement of DNA vaccines by electroporation Gene Vaccines. 2147483647: 145-162. DOI: 10.1007/978-3-7091-0439-2_7 |
0.422 |
|
| 2011 |
Hutnick NA, Myles DJ, Bian CB, Muthumani K, Weiner DB. Selected approaches for increasing HIV DNA vaccine immunogenicity in vivo. Current Opinion in Virology. 1: 233-40. PMID 22440782 DOI: 10.1016/J.Coviro.2011.08.003 |
0.558 |
|
| 2011 |
Lang Kuhs KA, Toporovski R, Ginsberg AA, Olsen AL, Shedlock DJ, Morrow MP, Yan J, Wells RG, Weiner DB. Peripheral immunization induces functional intrahepatic hepatitis C specific immunity following selective retention of vaccine-specific CD8 T cells by the liver. Human Vaccines. 7: 1326-35. PMID 22108033 DOI: 10.4161/Hv.7.12.18279 |
0.426 |
|
| 2011 |
Hirao LA, Hokey DA, Morrow MP, Jure-Kunkel MN, Weiner DB. Immune modulation through 4-1BB enhances SIV vaccine protection in non-human primates against SIVmac251 challenge. Plos One. 6: e24250. PMID 21935390 DOI: 10.1371/Journal.Pone.0024250 |
0.83 |
|
| 2011 |
Muthumani K, Shedlock DJ, Choo DK, Fagone P, Kawalekar OU, Goodman J, Bian CB, Ramanathan AA, Atman P, Tebas P, Chattergoon MA, Choo AY, Weiner DB. HIV-mediated phosphatidylinositol 3-kinase/serine-threonine kinase activation in APCs leads to programmed death-1 ligand upregulation and suppression of HIV-specific CD8 T cells. Journal of Immunology (Baltimore, Md. : 1950). 187: 2932-43. PMID 21856939 DOI: 10.4049/Jimmunol.1100594 |
0.688 |
|
| 2011 |
Ferraro B, Morrow MP, Hutnick NA, Shin TH, Lucke CE, Weiner DB. Clinical applications of DNA vaccines: current progress. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. 53: 296-302. PMID 21765081 DOI: 10.1093/Cid/Cir334 |
0.591 |
|
| 2011 |
Ugen KE, Sardesai N, Weiner DB. DNA vaccines 2010: a gumbo of accomplishment and excitement in New Orleans. Vaccine. 29: 6721-2. PMID 21763382 DOI: 10.1016/J.Vaccine.2011.07.026 |
0.492 |
|
| 2011 |
Belisle SE, Yin J, Shedlock DJ, Dai A, Yan J, Hirao L, Kutzler MA, Lewis MG, Andersen H, Lank SM, Karl JA, O'Connor DH, Khan A, Sardesai N, Chang J, ... ... Weiner DB, et al. Long-term programming of antigen-specific immunity from gene expression signatures in the PBMC of rhesus macaques immunized with an SIV DNA vaccine. Plos One. 6: e19681. PMID 21701683 DOI: 10.1371/Journal.Pone.0019681 |
0.834 |
|
| 2011 |
Buckland BC, Aunins JG, Jansen K, Alves PM, Weiner D. Vaccine Technology III: An ECI Conference held in Puerto Vallarta, Mexico from June 6-11, 2010 Vaccine. 29: 7115-7116. PMID 21689708 DOI: 10.1016/J.Vaccine.2011.06.058 |
0.437 |
|
| 2011 |
Yan J, Corbitt N, Pankhong P, Shin T, Khan A, Sardesai NY, Weiner DB. Immunogenicity of a novel engineered HIV-1 clade C synthetic consensus-based envelope DNA vaccine. Vaccine. 29: 7173-81. PMID 21651948 DOI: 10.1016/J.Vaccine.2011.05.076 |
0.517 |
|
| 2011 |
Fagone P, Shedlock DJ, Bao H, Kawalekar OU, Yan J, Gupta D, Morrow MP, Patel A, Kobinger GP, Muthumani K, Weiner DB. Molecular adjuvant HMGB1 enhances anti-influenza immunity during DNA vaccination. Gene Therapy. 18: 1070-7. PMID 21544096 DOI: 10.1038/Gt.2011.59 |
0.599 |
|
| 2011 |
Sardesai NY, Weiner DB. Electroporation delivery of DNA vaccines: prospects for success. Current Opinion in Immunology. 23: 421-9. PMID 21530212 DOI: 10.1016/J.Coi.2011.03.008 |
0.591 |
|
| 2011 |
Ferraro B, Cisper NJ, Talbott KT, Philipson-Weiner L, Lucke CE, Khan AS, Sardesai NY, Weiner DB. Co-delivery of PSA and PSMA DNA vaccines with electroporation induces potent immune responses. Human Vaccines. 7: 120-7. PMID 21266849 DOI: 10.4161/Hv.7.0.14574 |
0.561 |
|
| 2011 |
Mallilankaraman K, Shedlock DJ, Bao H, Kawalekar OU, Fagone P, Ramanathan AA, Ferraro B, Stabenow J, Vijayachari P, Sundaram SG, Muruganandam N, Sarangan G, Srikanth P, Khan AS, Lewis MG, ... ... Weiner DB, et al. A DNA vaccine against chikungunya virus is protective in mice and induces neutralizing antibodies in mice and nonhuman primates. Plos Neglected Tropical Diseases. 5: e928. PMID 21264351 DOI: 10.1371/Journal.Pntd.0000928 |
0.587 |
|
| 2011 |
Shedlock DJ, Talbott KT, Cress C, Ferraro B, Tuyishme S, Mallilankaraman K, Cisper NJ, Morrow MP, Wu SJ, Kawalekar OU, Khan AS, Sardesai NY, Muthumani K, Shen H, Weiner DB. A highly optimized DNA vaccine confers complete protective immunity against high-dose lethal lymphocytic choriomeningitis virus challenge. Vaccine. 29: 6755-62. PMID 21238574 DOI: 10.1016/J.Vaccine.2010.12.064 |
0.596 |
|
| 2011 |
Pillet S, Kobasa D, Meunier I, Gray M, Laddy D, Weiner DB, von Messling V, Kobinger GP. Cellular immune response in the presence of protective antibody levels correlates with protection against 1918 influenza in ferrets. Vaccine. 29: 6793-801. PMID 21211587 DOI: 10.1016/J.Vaccine.2010.12.059 |
0.833 |
|
| 2011 |
Lin F, Shen X, McCoy JR, Mendoza JM, Yan J, Kemmerrer SV, Khan AS, Weiner DB, Broderick KE, Sardesai NY. A novel prototype device for electroporation-enhanced DNA vaccine delivery simultaneously to both skin and muscle. Vaccine. 29: 6771-80. PMID 21199706 DOI: 10.1016/J.Vaccine.2010.12.057 |
0.53 |
|
| 2011 |
Yin J, Dai A, Lecureux J, Arango T, Kutzler MA, Yan J, Lewis MG, Khan A, Sardesai NY, Montefiore D, Ruprecht R, Weiner DB, Boyer JD. High antibody and cellular responses induced to HIV-1 clade C envelope following DNA vaccines delivered by electroporation. Vaccine. 29: 6763-70. PMID 21195801 DOI: 10.1016/J.Vaccine.2010.12.055 |
0.617 |
|
| 2011 |
Hirao LA, Draghia-Akli R, Prigge JT, Yang M, Satishchandran A, Wu L, Hammarlund E, Khan AS, Babas T, Rhodes L, Silvera P, Slifka M, Sardesai NY, Weiner DB. Multivalent smallpox DNA vaccine delivered by intradermal electroporation drives protective immunity in nonhuman primates against lethal monkeypox challenge. The Journal of Infectious Diseases. 203: 95-102. PMID 21148501 DOI: 10.1093/Infdis/Jiq017 |
0.83 |
|
| 2011 |
Moise L, Buller RM, Schriewer J, Lee J, Frey SE, Weiner DB, Martin W, De Groot AS. VennVax, a DNA-prime, peptide-boost multi-T-cell epitope poxvirus vaccine, induces protective immunity against vaccinia infection by T cell response alone. Vaccine. 29: 501-11. PMID 21055490 DOI: 10.1016/J.Vaccine.2010.10.064 |
0.582 |
|
| 2011 |
Broderick KE, Shen X, Soderholm J, Lin F, McCoy J, Khan AS, Yan J, Morrow MP, Patel A, Kobinger GP, Kemmerrer S, Weiner DB, Sardesai NY. Prototype development and preclinical immunogenicity analysis of a novel minimally invasive electroporation device. Gene Therapy. 18: 258-65. PMID 20962869 DOI: 10.1038/Gt.2010.137 |
0.511 |
|
| 2010 |
Morrow MP, Yan J, Pankhong P, Shedlock DJ, Lewis MG, Talbott K, Toporovski R, Khan AS, Sardesai NY, Weiner DB. IL-28B/IFN-λ3 Drives Granzyme B Loading and Significantly Increases CTL Killing Activity in Macaques. Molecular Therapy : the Journal of the American Society of Gene Therapy. 18: 1714-1723. PMID 28178468 DOI: 10.1038/mt.2010.118 |
0.336 |
|
| 2010 |
Toporovski R, Morrow MP, Weiner DB. Interferons as potential adjuvants in prophylactic vaccines. Expert Opinion On Biological Therapy. 10: 1489-500. PMID 20836750 DOI: 10.1517/14712598.2010.521495 |
0.548 |
|
| 2010 |
Morrow MP, Yan J, Pankhong P, Ferraro B, Lewis MG, Khan AS, Sardesai NY, Weiner DB. Unique Th1/Th2 phenotypes induced during priming and memory phases by use of interleukin-12 (IL-12) or IL-28B vaccine adjuvants in rhesus macaques. Clinical and Vaccine Immunology : Cvi. 17: 1493-9. PMID 20685940 DOI: 10.1128/Cvi.00181-10 |
0.52 |
|
| 2010 |
Ingolotti M, Kawalekar O, Shedlock DJ, Muthumani K, Weiner DB. DNA vaccines for targeting bacterial infections. Expert Review of Vaccines. 9: 747-63. PMID 20624048 DOI: 10.1586/Erv.10.57 |
0.549 |
|
| 2010 |
Morrow MP, Weiner DB. DNA drugs come of age. Scientific American. 303: 48-53. PMID 20583666 DOI: 10.1038/Scientificamerican0710-48 |
0.428 |
|
| 2010 |
Morrow MP, Yan J, Pankhong P, Shedlock DJ, Lewis MG, Talbott K, Toporovski R, Khan AS, Sardesai NY, Weiner DB. IL-28B/IFN-lambda 3 drives granzyme B loading and significantly increases CTL killing activity in macaques. Molecular Therapy : the Journal of the American Society of Gene Therapy. 18: 1714-23. PMID 20571540 DOI: 10.1038/Mt.2010.118 |
0.445 |
|
| 2010 |
Hirao LA, Wu L, Satishchandran A, Khan AS, Draghia-Akli R, Finnefrock AC, Bett AJ, Betts MR, Casimiro DR, Sardesai NY, Kim JJ, Shiver JW, Weiner DB. Comparative analysis of immune responses induced by vaccination with SIV antigens by recombinant Ad5 vector or plasmid DNA in rhesus macaques. Molecular Therapy : the Journal of the American Society of Gene Therapy. 18: 1568-76. PMID 20551910 DOI: 10.1038/Mt.2010.112 |
0.832 |
|
| 2010 |
Thiboutot MM, Kannan S, Kawalekar OU, Shedlock DJ, Khan AS, Sarangan G, Srikanth P, Weiner DB, Muthumani K. Chikungunya: a potentially emerging epidemic? Plos Neglected Tropical Diseases. 4: e623. PMID 20436958 DOI: 10.1371/Journal.Pntd.0000623 |
0.415 |
|
| 2010 |
Muthumani K, Lambert VM, Kawalekar O, Heller R, Kim JJ, Weiner DB, Ugen KE. Anti-cancer activity of the HIV accessory molecule viral protein R (Vpr): Delivery as a DNA expression plasmid or biologically active peptides. Vaccine. 28: 2005-10. PMID 20188256 DOI: 10.1016/J.Vaccine.2009.10.060 |
0.349 |
|
| 2010 |
Kraynyak KA, Kutzler MA, Cisper NJ, Khan AS, Draghia-Akli R, Sardesal NY, Lewis MG, Yan J, Weiner DB. Systemic immunization with CCL27/CTACK modulates immune responses at mucosal sites in mice and macaques. Vaccine. 28: 1942-51. PMID 20188250 DOI: 10.1016/J.Vaccine.2009.10.095 |
0.805 |
|
| 2010 |
Weiner DB, Sardesai NY, Schmaljohn C. Introduction to DNA vaccines - Las Vegas. Vaccine. 28: 1893-6. PMID 20188243 DOI: 10.1016/J.Vaccine.2010.01.052 |
0.508 |
|
| 2010 |
Para MF, Schouten J, Rosenkranz SL, Yu S, Weiner D, Tebas P, White CJ, Reeds D, Lertora J, Patterson KB, Daar ES, Cavert W, Brizz B. Phase I/II trial of the anti-HIV activity of mifepristone in HIV-infected subjects ACTG 5200 Journal of Acquired Immune Deficiency Syndromes. 53: 491-495. PMID 20130470 DOI: 10.1097/Qai.0B013E3181D142Cb |
0.304 |
|
| 2010 |
Kawalekar OU, Shedlock DJ, Weiner DB. Current strategies and limitations of HIV vaccines. Current Opinion in Investigational Drugs (London, England : 2000). 11: 192-202. PMID 20112169 |
0.421 |
|
| 2010 |
Shedlock DJ, Talbott KT, Morrow MP, Ferraro B, Hokey DA, Muthumani K, Weiner DB. Ki-67 staining for determination of rhesus macaque T cell proliferative responses ex vivo. Cytometry. Part a : the Journal of the International Society For Analytical Cytology. 77: 275-84. PMID 20104580 DOI: 10.1002/Cyto.A.20857 |
0.44 |
|
| 2010 |
Kutzler MA, Kraynyak KA, Nagle SJ, Parkinson RM, Zharikova D, Chattergoon M, Maguire H, Muthumani K, Ugen K, Weiner DB. Plasmids encoding the mucosal chemokines CCL27 and CCL28 are effective adjuvants in eliciting antigen-specific immunity in vivo. Gene Therapy. 17: 72-82. PMID 19847203 DOI: 10.1038/Gt.2009.112 |
0.871 |
|
| 2010 |
Han DJ, Weiner DB, Sin JI. DNA vaccines against infectious diseases and cancer Biomolecules and Therapeutics. 18: 1-15. DOI: 10.4062/biomolther.2010.18.1.001 |
0.376 |
|
| 2009 |
Shedlock DJ, Silvestri G, Weiner DB. Monkeying around with HIV vaccines: using rhesus macaques to define 'gatekeepers' for clinical trials. Nature Reviews. Immunology. 9: 717-28. PMID 19859066 DOI: 10.1038/Nri2636 |
0.504 |
|
| 2009 |
Mueller YM, Do DH, Boyer JD, Kader M, Mattapallil JJ, Lewis MG, Weiner DB, Katsikis PD. CD8+ cell depletion of SHIV89.6P-infected macaques induces CD4+ T cell proliferation that contributes to increased viral loads. Journal of Immunology (Baltimore, Md. : 1950). 183: 5006-12. PMID 19786539 DOI: 10.4049/Jimmunol.0900141 |
0.337 |
|
| 2009 |
Muthumani G, Laddy DJ, Sundaram SG, Fagone P, Shedlock DJ, Kannan S, Wu L, Chung CW, Lankaraman KM, Burns J, Muthumani K, Weiner DB. Co-immunization with an optimized plasmid-encoded immune stimulatory interleukin, high-mobility group box 1 protein, results in enhanced interferon-gamma secretion by antigen-specific CD8 T cells. Immunology. 128: e612-20. PMID 19740322 DOI: 10.1111/J.1365-2567.2009.03044.X |
0.846 |
|
| 2009 |
Redding L, Weiner DB. DNA vaccines in veterinary use. Expert Review of Vaccines. 8: 1251-76. PMID 19722897 DOI: 10.1586/Erv.09.77 |
0.513 |
|
| 2009 |
Apostolopoulos V, Weiner DB. Development of more efficient and effective DNA vaccines. Expert Review of Vaccines. 8: 1133-4. PMID 19722884 DOI: 10.1586/Erv.09.94 |
0.508 |
|
| 2009 |
Yin J, Dai A, Laddy DJ, Yan J, Arango T, Khan AS, Lewis MG, Andersen H, Kutzler MA, Draghia-Akli R, Weiner DB, Boyer JD. High dose of plasmid IL-15 inhibits immune responses in an influenza non-human primates immunogenicity model. Virology. 393: 49-55. PMID 19683780 DOI: 10.1016/J.Virol.2009.07.017 |
0.778 |
|
| 2009 |
Sonnenberg GF, Weiner DB. Manipulation of T(H)17 responses in pulmonary immunity and disease through vaccination. Human Vaccines. 5: 510-9. PMID 19617711 DOI: 10.4161/Hv.5.8.8879 |
0.452 |
|
| 2009 |
Ramanathan MP, Kuo YC, Selling BH, Li Q, Sardesai NY, Kim JJ, Weiner DB. Development of a novel DNA SynCon tetravalent dengue vaccine that elicits immune responses against four serotypes. Vaccine. 27: 6444-53. PMID 19580892 DOI: 10.1016/J.Vaccine.2009.06.061 |
0.58 |
|
| 2009 |
Kraynyak KA, Kutzler MA, Cisper NJ, Laddy DJ, Morrow MP, Waldmann TA, Weiner DB. Plasmid-encoded interleukin-15 receptor alpha enhances specific immune responses induced by a DNA vaccine in vivo. Human Gene Therapy. 20: 1143-56. PMID 19530914 DOI: 10.1089/Hum.2009.025 |
0.838 |
|
| 2009 |
Ramanathan MP, Kutzler MA, Kuo YC, Yan J, Liu H, Shah V, Bawa A, Selling B, Sardesai NY, Kim JJ, Weiner DB. Coimmunization with an optimized IL15 plasmid adjuvant enhances humoral immunity via stimulating B cells induced by genetically engineered DNA vaccines expressing consensus JEV and WNV E DIII. Vaccine. 27: 4370-80. PMID 19497647 DOI: 10.1016/J.Vaccine.2009.01.137 |
0.588 |
|
| 2009 |
Morrow MP, Pankhong P, Laddy DJ, Schoenly KA, Yan J, Cisper N, Weiner DB. Comparative ability of IL-12 and IL-28B to regulate Treg populations and enhance adaptive cellular immunity. Blood. 113: 5868-77. PMID 19304955 DOI: 10.1182/Blood-2008-11-190520 |
0.781 |
|
| 2009 |
Thieu KP, Morrow MP, Shedlock DJ, Schoenly KA, Mallilankaraman K, Choo AY, Fagone P, Weiner DB, Muthumani K. HIV-1 Vpr: regulator of viral survival. Current Hiv Research. 7: 153-62. PMID 19275584 DOI: 10.2174/157016209787581454 |
0.341 |
|
| 2009 |
Muthumani K, Lambert VM, Sardesai NY, Kim JJ, Heller R, Weiner DB, Ugen KE. Analysis of the potential for HIV-1 Vpr as an anti-cancer agent. Current Hiv Research. 7: 144-52. PMID 19275583 DOI: 10.2174/157016209787581481 |
0.351 |
|
| 2009 |
Laddy DJ, Yan J, Khan AS, Andersen H, Cohn A, Greenhouse J, Lewis M, Manischewitz J, King LR, Golding H, Draghia-Akli R, Weiner DB. Electroporation of synthetic DNA antigens offers protection in nonhuman primates challenged with highly pathogenic avian influenza virus. Journal of Virology. 83: 4624-30. PMID 19211745 DOI: 10.1128/Jvi.02335-08 |
0.823 |
|
| 2009 |
Yan J, Hokey DA, Morrow MP, Corbitt N, Harris K, Harris D, Weiner DB. Novel SIVmac DNA vaccines encoding Env, Pol and Gag consensus proteins elicit strong cellular immune responses in cynomolgus macaques. Vaccine. 27: 3260-6. PMID 19200811 DOI: 10.1016/J.Vaccine.2009.01.065 |
0.612 |
|
| 2009 |
Muthumani K, Lambert VM, Shanmugam M, Thieu KP, Choo AY, Chung JC, Satishchandran A, Kim JJ, Weiner DB, Ugen KE. Anti-tumor activity mediated by protein and peptide transduction of HIV viral protein R (Vpr). Cancer Biology & Therapy. 8: 180-7. PMID 19029839 DOI: 10.4161/Cbt.8.2.7205 |
0.315 |
|
| 2009 |
Yan J, Reichenbach DK, Corbitt N, Hokey DA, Ramanathan MP, McKinney KA, Weiner DB, Sewell D. Induction of antitumor immunity in vivo following delivery of a novel HPV-16 DNA vaccine encoding an E6/E7 fusion antigen. Vaccine. 27: 431-40. PMID 19022315 DOI: 10.1016/J.Vaccine.2008.10.078 |
0.506 |
|
| 2009 |
Morrow MP, Pankhong P, Weiner DB. Design and characterization of a plasmid vector system capable of rapid generation of antibodies of multiple isotypes and specificities. Biotechnology Letters. 31: 13-22. PMID 18777012 DOI: 10.1007/S10529-008-9826-Y |
0.304 |
|
| 2009 |
Morrow M, Yan J, Pankhong P, Harris K, Kahn A, Sardesai N, Weiner D. P02-02. Analysis of antigen specific degranulation potentials using IL-12 or IL-28B during HIV DNA Vaccination Retrovirology. 6: P7. DOI: 10.1186/1742-4690-6-S3-P7 |
0.477 |
|
| 2009 |
Hirao LA, Hokey DA, Weber J, Yan J, Boyer JD, Dai A, Anderson H, Lewis M, Jure-Kunkel MN, Weiner DB. P19-49. Modulation of vaccine induced responses through CTLA-4 and 41BB enhances protection in macaques following SIVmac251 challenge Retrovirology. 6: P369. DOI: 10.1186/1742-4690-6-S3-P369 |
0.817 |
|
| 2009 |
Kraynyak KA, Kutzler MA, Pahar B, Sylvester A, Yan J, Carnathan D, Khan AS, Sardesai N, Moldoveanu Z, Mestecky J, Betts MR, Marx P, Weiner DB. P19-46. Co-delivery of mucosal chemokine plasmids in a systemically delivered DNA vaccine elicits systemic and mucosal immune responses in mice and macaques Retrovirology. 6: P366. DOI: 10.1186/1742-4690-6-S3-P366 |
0.809 |
|
| 2009 |
Hirao LA, Wu L, Khan AS, Dai A, Karl J, Lank S, Wiseman R, O'Connor D, Watkins D, Miller N, Betts MR, Sardesai NY, Boyer JD, Weiner DB. P03-11. DNA vaccination with IL-12 lowers viral replication following SIVmac251 challenge Retrovirology. 6: P28. DOI: 10.1186/1742-4690-6-S3-P28 |
0.786 |
|
| 2009 |
Boyer JD, Yin J, Dai A, Belisle S, Hirao L, Palermo R, Hokey D, Yan J, Weiner D. P16-36. Functional genomic immune profile of SIV DNA vaccines delivered by electroporation and combined with molecular adjuvants Retrovirology. 6: P265. DOI: 10.1186/1742-4690-6-S3-P265 |
0.818 |
|
| 2009 |
Hirao LA, Wu L, Satishchandran A, Khan AS, Finnefrock A, Casimiro D, Shiver J, Betts MR, Sardesai NY, Weiner DB. OA05-02. Analysis of DNA compared to Ad5 vaccination, as single and mixed modalities, demonstrates robust induction of cellular immune responses in macaques Retrovirology. 6: O32. DOI: 10.1186/1742-4690-6-S3-O32 |
0.829 |
|
| 2008 |
Hokey DA, Yan J, Hirao LA, Dai A, Boyer JD, Jure-Kunkel MN, Weiner DB. CLTA-4 blockade in vivo promotes the generation of short-lived effector CD8 T cells and a more persistent central memory CD4 T cell response. Journal of Medical Primatology. 37: 62-8. PMID 19187432 DOI: 10.1111/J.1600-0684.2008.00324.X |
0.758 |
|
| 2008 |
Abdulhaqq SA, Weiner DB. DNA vaccines: developing new strategies to enhance immune responses. Immunologic Research. 42: 219-32. PMID 19066740 DOI: 10.1007/S12026-008-8076-3 |
0.599 |
|
| 2008 |
Muthumani K, Choo AY, Shedlock DJ, Laddy DJ, Sundaram SG, Hirao L, Wu L, Thieu KP, Chung CW, Lankaraman KM, Tebas P, Silvestri G, Weiner DB. Human immunodeficiency virus type 1 Nef induces programmed death 1 expression through a p38 mitogen-activated protein kinase-dependent mechanism. Journal of Virology. 82: 11536-44. PMID 18799583 DOI: 10.1128/Jvi.00485-08 |
0.792 |
|
| 2008 |
Kutzler MA, Weiner DB. DNA vaccines: ready for prime time? Nature Reviews. Genetics. 9: 776-88. PMID 18781156 DOI: 10.1038/Nrg2432 |
0.542 |
|
| 2008 |
Apostolopoulos V, Weiner DB, Gong J. Cancer vaccines: methods for inducing immunity. Expert Review of Vaccines. 7: 861-2. PMID 18767935 DOI: 10.1586/14760584.7.7.861 |
0.508 |
|
| 2008 |
Yin J, Dai A, Kutzler MA, Shen A, Lecureux J, Lewis MG, Waldmann T, Weiner DB, Boyer JD. Sustained suppression of SHIV89.6P replication in macaques by vaccine-induced CD8+ memory T cells. Aids (London, England). 22: 1739-48. PMID 18753858 DOI: 10.1097/Qad.0B013E32830Efdae |
0.53 |
|
| 2008 |
Demberg T, Boyer JD, Malkevich N, Patterson LJ, Venzon D, Summers EL, Kalisz I, Kalyanaraman VS, Lee EM, Weiner DB, Robert-Guroff M. Sequential priming with simian immunodeficiency virus (SIV) DNA vaccines, with or without encoded cytokines, and a replicating adenovirus-SIV recombinant followed by protein boosting does not control a pathogenic SIVmac251 mucosal challenge. Journal of Virology. 82: 10911-21. PMID 18753198 DOI: 10.1128/Jvi.01129-08 |
0.553 |
|
| 2008 |
Lang KA, Yan J, Draghia-Akli R, Khan A, Weiner DB. Strong HCV NS3- and NS4A-specific cellular immune responses induced in mice and Rhesus macaques by a novel HCV genotype 1a/1b consensus DNA vaccine. Vaccine. 26: 6225-31. PMID 18692108 DOI: 10.1016/J.Vaccine.2008.07.052 |
0.401 |
|
| 2008 |
Xu R, Megati S, Roopchand V, Luckay A, Masood A, Garcia-Hand D, Rosati M, Weiner DB, Felber BK, Pavlakis GN, Sidhu MK, Eldridge JH, Egan MA. Comparative ability of various plasmid-based cytokines and chemokines to adjuvant the activity of HIV plasmid DNA vaccines. Vaccine. 26: 4819-29. PMID 18657584 DOI: 10.1016/J.Vaccine.2008.06.103 |
0.614 |
|
| 2008 |
Weiner DB. DNA vaccines: crossing a line in the sand. Introduction to special issue. Vaccine. 26: 5073-4. PMID 18652867 DOI: 10.1016/J.Vaccine.2008.07.024 |
0.47 |
|
| 2008 |
Shedlock DJ, Hwang D, Choo AY, Chung CW, Muthumani K, Weiner DB. HIV-1 viral genes and mitochondrial apoptosis. Apoptosis : An International Journal On Programmed Cell Death. 13: 1088-99. PMID 18622704 DOI: 10.1007/S10495-008-0239-0 |
0.359 |
|
| 2008 |
Laddy DJ, Yan J, Kutzler M, Kobasa D, Kobinger GP, Khan AS, Greenhouse J, Sardesai NY, Draghia-Akli R, Weiner DB. Heterosubtypic protection against pathogenic human and avian influenza viruses via in vivo electroporation of synthetic consensus DNA antigens. Plos One. 3: e2517. PMID 18575608 DOI: 10.1371/Journal.Pone.0002517 |
0.813 |
|
| 2008 |
Halwani R, Boyer JD, Yassine-Diab B, Haddad EK, Robinson TM, Kumar S, Parkinson R, Wu L, Sidhu MK, Phillipson-Weiner R, Pavlakis GN, Felber BK, Lewis MG, Shen A, Siliciano RF, ... Weiner DB, et al. Therapeutic vaccination with simian immunodeficiency virus (SIV)-DNA + IL-12 or IL-15 induces distinct CD8 memory subsets in SIV-infected macaques. Journal of Immunology (Baltimore, Md. : 1950). 180: 7969-79. PMID 18523260 DOI: 10.4049/Jimmunol.180.12.7969 |
0.559 |
|
| 2008 |
Megati S, Garcia-Hand D, Cappello S, Roopchand V, Masood A, Xu R, Luckay A, Chong SY, Rosati M, Sackitey S, Weiner DB, Felber BK, Pavlakis GN, Israel ZR, Smith LR, et al. Modifying the HIV-1 env gp160 gene to improve pDNA vaccine-elicited cell-mediated immune responses. Vaccine. 26: 5083-94. PMID 18485543 DOI: 10.1016/J.Vaccine.2008.03.092 |
0.541 |
|
| 2008 |
Muthumani K, Lankaraman KM, Laddy DJ, Sundaram SG, Chung CW, Sako E, Wu L, Khan A, Sardesai N, Kim JJ, Vijayachari P, Weiner DB. Immunogenicity of novel consensus-based DNA vaccines against Chikungunya virus. Vaccine. 26: 5128-34. PMID 18471943 DOI: 10.1016/j.vaccine.2008.03.060 |
0.819 |
|
| 2008 |
Calarota SA, Dai A, Trocio JN, Weiner DB, Lori F, Lisziewicz J. IL-15 as memory T-cell adjuvant for topical HIV-1 DermaVir vaccine. Vaccine. 26: 5188-95. PMID 18462844 DOI: 10.1016/J.Vaccine.2008.03.067 |
0.412 |
|
| 2008 |
Wang J, Shackelford JM, Selliah N, Shivers DK, O'Neill E, Garcia JV, Muthumani K, Weiner D, Yu XF, Gabuzda D, Finkel TH. The HIV-1 Vif protein mediates degradation of Vpr and reduces Vpr-induced cell cycle arrest. Dna and Cell Biology. 27: 267-77. PMID 18462066 DOI: 10.1089/Dna.2007.0707 |
0.345 |
|
| 2008 |
Yan J, Harris K, Khan AS, Draghia-Akli R, Sewell D, Weiner DB. Cellular immunity induced by a novel HPV18 DNA vaccine encoding an E6/E7 fusion consensus protein in mice and rhesus macaques. Vaccine. 26: 5210-5. PMID 18455277 DOI: 10.1016/J.Vaccine.2008.03.069 |
0.421 |
|
| 2008 |
Draghia-Akli R, Khan AS, Brown PA, Pope MA, Wu L, Hirao L, Weiner DB. Parameters for DNA vaccination using adaptive constant-current electroporation in mouse and pig models. Vaccine. 26: 5230-7. PMID 18450333 DOI: 10.1016/J.Vaccine.2008.03.071 |
0.796 |
|
| 2008 |
Hirao LA, Wu L, Khan AS, Hokey DA, Yan J, Dai A, Betts MR, Draghia-Akli R, Weiner DB. Combined effects of IL-12 and electroporation enhances the potency of DNA vaccination in macaques. Vaccine. 26: 3112-20. PMID 18430495 DOI: 10.1016/J.Vaccine.2008.02.036 |
0.827 |
|
| 2008 |
Hokey DA, Johnson FB, Smith J, Weber JL, Yan J, Hirao L, Boyer JD, Lewis MG, Makedonas G, Betts MR, Weiner DB. Activation drives PD-1 expression during vaccine-specific proliferation and following lentiviral infection in macaques. European Journal of Immunology. 38: 1435-45. PMID 18389475 DOI: 10.1002/Eji.200737857 |
0.759 |
|
| 2008 |
Calarota SA, Hokey DA, Dai A, Jure-Kunkel MN, Balimane P, Weiner DB. Augmentation of SIV DNA vaccine-induced cellular immunity by targeting the 4-1BB costimulatory molecule. Vaccine. 26: 3121-34. PMID 18336959 DOI: 10.1016/J.Vaccine.2008.02.017 |
0.596 |
|
| 2008 |
Morrow MP, Weiner DB. Cytokines as adjuvants for improving anti-HIV responses. Aids (London, England). 22: 333-8. PMID 18195559 DOI: 10.1097/Qad.0B013E3282F42461 |
0.349 |
|
| 2008 |
Chattergoon MA, Muthumani K, Tamura Y, Ramanathan M, Shames JP, Saulino V, Robinson TM, Montaner LJ, Weiner DB. DR5 activation of caspase-8 induces DC maturation and immune enhancement in vivo. Molecular Therapy : the Journal of the American Society of Gene Therapy. 16: 419-26. PMID 18087262 DOI: 10.1038/Sj.Mt.6300373 |
0.733 |
|
| 2008 |
Hirao LA, Wu L, Khan AS, Satishchandran A, Draghia-Akli R, Weiner DB. Intradermal/subcutaneous immunization by electroporation improves plasmid vaccine delivery and potency in pigs and rhesus macaques. Vaccine. 26: 440-8. PMID 18082294 DOI: 10.1016/J.Vaccine.2007.10.041 |
0.823 |
|
| 2008 |
Schoenly KA, Weiner DB. Human immunodeficiency virus type 1 vaccine development: recent advances in the cytotoxic T-lymphocyte platform "spotty business". Journal of Virology. 82: 3166-80. PMID 17989174 DOI: 10.1128/Jvi.01634-07 |
0.527 |
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| 2008 |
Weiner D. Introduction to special vaccine meetings manuscript collection—2007 Vaccine. 26: 3091. DOI: 10.1016/J.Vaccine.2008.02.019 |
0.488 |
|
| 2007 |
Boyer JD, Robinson TM, Kutzler MA, Vansant G, Hokey DA, Kumar S, Parkinson R, Wu L, Sidhu MK, Pavlakis GN, Felber BK, Brown C, Silvera P, Lewis MG, Monforte J, ... ... Weiner DB, et al. Protection against simian/human immunodeficiency virus (SHIV) 89.6P in macaques after coimmunization with SHIV antigen and IL-15 plasmid. Proceedings of the National Academy of Sciences of the United States of America. 104: 18648-53. PMID 18000037 DOI: 10.1073/Pnas.0709198104 |
0.61 |
|
| 2007 |
Jalah R, Rosati M, Kulkarni V, Patel V, Bergamaschi C, Valentin A, Zhang GM, Sidhu MK, Eldridge JH, Weiner DB, Pavlakis GN, Felber BK. Efficient systemic expression of bioactive IL-15 in mice upon delivery of optimized DNA expression plasmids. Dna and Cell Biology. 26: 827-40. PMID 17979522 DOI: 10.1089/Dna.2007.0645 |
0.332 |
|
| 2007 |
Robinson TM, Sidhu MK, Pavlakis GN, Felber BK, Silvera P, Lewis MG, Eldridge J, Weiner DB, Boyer JD. Macaques co-immunized with SIVgag/pol-HIVenv and IL-12 plasmid have increased cellular responses. Journal of Medical Primatology. 36: 276-84. PMID 17669216 DOI: 10.1111/J.1600-0684.2007.00245.X |
0.59 |
|
| 2007 |
McMurry JA, Kimball S, Lee JH, Rivera D, Martin W, Weiner DB, Kutzler M, Sherman DR, Kornfeld H, De Groot AS. Epitope-driven TB vaccine development: a streamlined approach using immuno-informatics, ELISpot assays, and HLA transgenic mice. Current Molecular Medicine. 7: 351-68. PMID 17584075 DOI: 10.2174/156652407780831584 |
0.533 |
|
| 2007 |
Rolland M, Jensen MA, Nickle DC, Yan J, Learn GH, Heath L, Weiner D, Mullins JI. Reconstruction and function of ancestral center-of-tree human immunodeficiency virus type 1 proteins. Journal of Virology. 81: 8507-14. PMID 17537854 DOI: 10.1128/Jvi.02683-06 |
0.425 |
|
| 2007 |
Chong SY, Egan MA, Kutzler MA, Megati S, Masood A, Roopchard V, Garcia-Hand D, Montefiori DC, Quiroz J, Rosati M, Schadeck EB, Boyer JD, Pavlakis GN, Weiner DB, Sidhu M, et al. Comparative ability of plasmid IL-12 and IL-15 to enhance cellular and humoral immune responses elicited by a SIVgag plasmid DNA vaccine and alter disease progression following SHIV(89.6P) challenge in rhesus macaques. Vaccine. 25: 4967-82. PMID 17335943 DOI: 10.1016/J.Vaccine.2006.11.070 |
0.505 |
|
| 2007 |
Laddy DJ, Yan J, Corbitt N, Kobasa D, Kobinger GP, Weiner DB. Immunogenicity of novel consensus-based DNA vaccines against avian influenza. Vaccine. 25: 2984-9. PMID 17306909 DOI: 10.1016/J.Vaccine.2007.01.063 |
0.798 |
|
| 2007 |
Calarota SA, Weiner DB, Lori F, Lisziewicz J. Induction of HIV-specific memory T-cell responses by topical DermaVir vaccine. Vaccine. 25: 3070-4. PMID 17292518 DOI: 10.1016/J.Vaccine.2007.01.024 |
0.59 |
|
| 2007 |
Yan J, Yoon H, Kumar S, Ramanathan MP, Corbitt N, Kutzler M, Dai A, Boyer JD, Weiner DB. Enhanced cellular immune responses elicited by an engineered HIV-1 subtype B consensus-based envelope DNA vaccine. Molecular Therapy : the Journal of the American Society of Gene Therapy. 15: 411-21. PMID 17235321 DOI: 10.1038/Sj.Mt.6300036 |
0.569 |
|
| 2007 |
von Gegerfelt AS, Rosati M, Alicea C, Valentin A, Roth P, Bear J, Franchini G, Albert PS, Bischofberger N, Boyer JD, Weiner DB, Markham P, Israel ZR, Eldridge JH, Pavlakis GN, et al. Long-lasting decrease in viremia in macaques chronically infected with simian immunodeficiency virus SIVmac251 after therapeutic DNA immunization. Journal of Virology. 81: 1972-9. PMID 17135321 DOI: 10.1128/Jvi.01990-06 |
0.576 |
|
| 2006 |
Lori F, Weiner DB, Calarota SA, Kelly LM, Lisziewicz J. Cytokine-adjuvanted HIV-DNA vaccination strategies. Springer Seminars in Immunopathology. 28: 231-8. PMID 17053912 DOI: 10.1007/S00281-006-0047-Y |
0.533 |
|
| 2006 |
Weiner DB. Progress in development and testing of novel recombinant vaccine platforms for HIV. Springer Seminars in Immunopathology. 28: 195-6. PMID 17043866 DOI: 10.1007/S00281-006-0053-0 |
0.468 |
|
| 2006 |
Hokey DA, Weiner DB. DNA vaccines for HIV: challenges and opportunities. Springer Seminars in Immunopathology. 28: 267-79. PMID 17031649 DOI: 10.1007/S00281-006-0046-Z |
0.495 |
|
| 2006 |
McCray AN, Ugen KE, Muthumani K, Kim JJ, Weiner DB, Heller R. Complete regression of established subcutaneous B16 murine melanoma tumors after delivery of an HIV-1 Vpr-expressing plasmid by in vivo electroporation. Molecular Therapy : the Journal of the American Society of Gene Therapy. 14: 647-55. PMID 16950655 DOI: 10.1016/J.Ymthe.2006.06.010 |
0.325 |
|
| 2006 |
Neeson P, Boyer J, Kumar S, Lewis MG, Mattias L, Veazey R, Weiner D, Paterson Y. A DNA prime-oral Listeria boost vaccine in rhesus macaques induces a SIV-specific CD8 T cell mucosal response characterized by high levels of alpha4beta7 integrin and an effector memory phenotype. Virology. 354: 299-315. PMID 16904153 DOI: 10.1016/J.Virol.2006.06.036 |
0.432 |
|
| 2006 |
Boyer JD, Kumar S, Robinson T, Parkinson R, Wu L, Lewis M, Watkins DI, Weiner DB. Initiation of antiretroviral therapy during chronic SIV infection leads to rapid reduction in viral loads and the level of T-cell immune response. Journal of Medical Primatology. 35: 202-9. PMID 16872283 DOI: 10.1111/J.1600-0684.2006.00179.X |
0.452 |
|
| 2006 |
Kumar S, Yan J, Muthumani K, Ramanathan MP, Yoon H, Pavlakis GN, Felber BK, Sidhu M, Boyer JD, Weiner DB. Immunogenicity testing of a novel engineered HIV-1 envelope gp140 DNA vaccine construct. Dna and Cell Biology. 25: 383-92. PMID 16848679 DOI: 10.1089/Dna.2006.25.383 |
0.53 |
|
| 2006 |
Laddy DJ, Weiner DB. From plasmids to protection: a review of DNA vaccines against infectious diseases. International Reviews of Immunology. 25: 99-123. PMID 16818367 DOI: 10.1080/08830180600785827 |
0.832 |
|
| 2006 |
Ugen KE, Kutzler MA, Marrero B, Westover J, Coppola D, Weiner DB, Heller R. Regression of subcutaneous B16 melanoma tumors after intratumoral delivery of an IL-15-expressing plasmid followed by in vivo electroporation. Cancer Gene Therapy. 13: 969-74. PMID 16763607 DOI: 10.1038/Sj.Cgt.7700973 |
0.31 |
|
| 2006 |
Weiner DB. Introduction to DNA vaccines issue. Vaccine. 24: 4459-60. PMID 16697504 DOI: 10.1016/J.Vaccine.2006.04.007 |
0.515 |
|
| 2006 |
Calarota SA, Otero M, Robinson TM, Dai A, Lewis MG, Boyer JD, Weiner DB. Independence of granzyme B secretion and interferon- gamma production during acute simian immunodeficiency virus infection. The Journal of Infectious Diseases. 193: 1441-50. PMID 16619193 DOI: 10.1086/503364 |
0.37 |
|
| 2006 |
Schadeck EB, Sidhu M, Egan MA, Chong SY, Piacente P, Masood A, Garcia-Hand D, Cappello S, Roopchand V, Megati S, Quiroz J, Boyer JD, Felber BK, Pavlakis GN, Weiner DB, et al. A dose sparing effect by plasmid encoded IL-12 adjuvant on a SIVgag-plasmid DNA vaccine in rhesus macaques. Vaccine. 24: 4677-87. PMID 16288822 DOI: 10.1016/J.Vaccine.2005.10.035 |
0.559 |
|
| 2006 |
Ramanathan MP, Chambers JA, Pankhong P, Chattergoon M, Attatippaholkun W, Dang K, Shah N, Weiner DB. Host cell killing by the West Nile Virus NS2B-NS3 proteolytic complex: NS3 alone is sufficient to recruit caspase-8-based apoptotic pathway. Virology. 345: 56-72. PMID 16243374 DOI: 10.1016/J.Virol.2005.08.043 |
0.658 |
|
| 2006 |
Boyer JD, Maciag PC, Parkinson R, Wu L, Lewis MG, Weiner DB, Paterson Y. Rhesus macaques with high levels of vaccine induced IFN-gamma producing cells better control viral set-point following challenge with SIV239. Vaccine. 24: 4498-502. PMID 16185790 DOI: 10.1016/J.Vaccine.2005.08.016 |
0.593 |
|
| 2006 |
Kutzler MA, Cao C, Bai Y, Dong H, Choe PY, Saulino V, McLaughlin L, Whelan A, Choo AY, Weiner DB, Ugen KE. Mapping of immune responses following wild-type and mutant ABeta42 plasmid or peptide vaccination in different mouse haplotypes and HLA Class II transgenic mice. Vaccine. 24: 4630-9. PMID 16157426 DOI: 10.1016/J.Vaccine.2005.08.036 |
0.474 |
|
| 2006 |
Egan MA, Megati S, Roopchand V, Garcia-Hand D, Luckay A, Chong SY, Rosati M, Sackitey S, Weiner DB, Felber BK, Pavlakis GN, Israel ZR, Eldridge JH, Sidhu MK. Rational design of a plasmid DNA vaccine capable of eliciting cell-mediated immune responses to multiple HIV antigens in mice. Vaccine. 24: 4510-23. PMID 16140439 DOI: 10.1016/J.Vaccine.2005.08.024 |
0.58 |
|
| 2006 |
Otero M, Calarota SA, Dai A, De Groot AS, Boyer JD, Weiner DB. Efficacy of novel plasmid DNA encoding vaccinia antigens in improving current smallpox vaccination strategy. Vaccine. 24: 4461-70. PMID 16137803 DOI: 10.1016/J.Vaccine.2005.08.010 |
0.554 |
|
| 2006 |
Hirao L, Khan A, Wu L, Hokey D, Draghia-Akli R, Weiner DB. Increased immunogenicity of HIV vaccination with constant-current electroporation and molecular adjuvants in mice and rhesus macaques Retrovirology. 3. DOI: 10.1186/1742-4690-3-S1-S85 |
0.831 |
|
| 2006 |
Kutzler MA, Schoenly KA, Muthumani K, Parkinson RM, Maquire H, Ugen K, Weiner D. Novel strategy for generation of mucosal immune responses against HIV-1 following systemic vaccination Retrovirology. 3. DOI: 10.1186/1742-4690-3-S1-S30 |
0.586 |
|
| 2006 |
Hokey DA, Boyer JD, Yoon H, Weiner DB. Increased PD-1 expression in cynomolgus and rhesus macaques during lentiviral infection Retrovirology. 3. DOI: 10.1186/1742-4690-3-S1-P27 |
0.325 |
|
| 2006 |
Khan AS, Hirao L, Weiner DB, Draghia-Akli R. 598. Effective Humoral and Cellular Smallpox-Immune Responses Using a Combination of Plasmids Delivered by Intramuscular Injection Followed by Constant-Current Electroporation in Rabbits Molecular Therapy. 13: S231. DOI: 10.1016/J.Ymthe.2006.08.672 |
0.779 |
|
| 2006 |
Hirao L, Khan AS, Draghia-Akli R, Weiner DB. 585. Improved Efficacy of DNA Vaccines for HIV and Smallpox Using Constant-Current Electroporation Molecular Therapy. 13: S226. DOI: 10.1016/J.Ymthe.2006.08.659 |
0.818 |
|
| 2005 |
Encinas JA, Janssen EM, Weiner DB, Calarota SA, Nieto D, Moll T, Carlo DJ, Moss RB. Anti-T-cell Ig and mucin domain-containing protein 1 antibody decreases TH2 airway inflammation in a mouse model of asthma. The Journal of Allergy and Clinical Immunology. 116: 1343-9. PMID 16337469 DOI: 10.1016/J.Jaci.2005.08.031 |
0.344 |
|
| 2005 |
Choo AY, Choo DK, Kim JJ, Weiner DB. DNA vaccination in immunotherapy of cancer. Cancer Treatment and Research. 123: 137-56. PMID 16211869 DOI: 10.1007/0-387-27545-2_6 |
0.527 |
|
| 2005 |
Boyer JD, Robinson TM, Kutzler MA, Parkinson R, Calarota SA, Sidhu MK, Muthumani K, Lewis M, Pavlakis G, Felber B, Weiner D. SIV DNA vaccine co-administered with IL-12 expression plasmid enhances CD8 SIV cellular immune responses in cynomolgus macaques. Journal of Medical Primatology. 34: 262-70. PMID 16128921 DOI: 10.1111/J.1600-0684.2005.00124.X |
0.603 |
|
| 2005 |
Egan MA, Chong SY, Megati S, Montefiori DC, Rose NF, Boyer JD, Sidhu MK, Quiroz J, Rosati M, Schadeck EB, Pavlakis GN, Weiner DB, Rose JK, Israel ZR, Udem SA, et al. Priming with plasmid DNAs expressing interleukin-12 and simian immunodeficiency virus gag enhances the immunogenicity and efficacy of an experimental AIDS vaccine based on recombinant vesicular stomatitis virus. Aids Research and Human Retroviruses. 21: 629-43. PMID 16060834 DOI: 10.1089/Aid.2005.21.629 |
0.623 |
|
| 2005 |
Muthumani K, Choo AY, Hwang DS, Dayes NS, Chattergoon M, Mayilvahanan S, Thieu KP, Buckley PT, Emmanuel J, Premkumar A, Weiner DB. HIV-1 Viral protein-r (Vpr) protects against lethal superantigen challenge while maintaining homeostatic T cell levels in vivo. Molecular Therapy : the Journal of the American Society of Gene Therapy. 12: 910-21. PMID 16006193 DOI: 10.1016/J.Ymthe.2005.05.009 |
0.725 |
|
| 2005 |
Kutzler MA, Robinson TM, Chattergoon MA, Choo DK, Choo AY, Choe PY, Ramanathan MP, Parkinson R, Kudchodkar S, Tamura Y, Sidhu M, Roopchand V, Kim JJ, Pavlakis GN, Felber BK, ... ... Weiner DB, et al. Coimmunization with an optimized IL-15 plasmid results in enhanced function and longevity of CD8 T cells that are partially independent of CD4 T cell help. Journal of Immunology (Baltimore, Md. : 1950). 175: 112-23. PMID 15972637 DOI: 10.4049/Jimmunol.175.1.112 |
0.766 |
|
| 2005 |
Muthumani K, Choo AY, Hwang DS, Premkumar A, Dayes NS, Harris C, Green DR, Wadsworth SA, Siekierka JJ, Weiner DB. HIV-1 Nef-induced FasL induction and bystander killing requires p38 MAPK activation. Blood. 106: 2059-68. PMID 15928037 DOI: 10.1182/Blood-2005-03-0932 |
0.318 |
|
| 2005 |
Song E, Zhu P, Lee SK, Chowdhury D, Kussman S, Dykxhoorn DM, Feng Y, Palliser D, Weiner DB, Shankar P, Marasco WA, Lieberman J. Antibody mediated in vivo delivery of small interfering RNAs via cell-surface receptors. Nature Biotechnology. 23: 709-17. PMID 15908939 DOI: 10.1038/Nbt1101 |
0.364 |
|
| 2005 |
Weiner D. Smallpox vaccines: circling the wagons Expert Review of Vaccines. 4: 127-129. PMID 15889981 DOI: 10.1586/14760584.4.2.127 |
0.481 |
|
| 2005 |
Muthumani K, Choo AY, Premkumar A, Hwang DS, Thieu KP, Desai BM, Weiner DB. Human immunodeficiency virus type 1 (HIV-1) Vpr-regulated cell death: insights into mechanism. Cell Death and Differentiation. 12: 962-70. PMID 15832179 DOI: 10.1038/Sj.Cdd.4401583 |
0.363 |
|
| 2005 |
De Groot AS, Marcon L, Bishop EA, Rivera D, Kutzler M, Weiner DB, Martin W. HIV vaccine development by computer assisted design: the GAIA vaccine. Vaccine. 23: 2136-48. PMID 15755584 DOI: 10.1016/J.Vaccine.2005.01.097 |
0.484 |
|
| 2005 |
Groot ASD, McMurry J, Marcon L, Franco J, Rivera D, Kutzler M, Weiner D, Martin B. Developing an epitope-driven tuberculosis (TB) vaccine Vaccine. 23: 2121-2131. PMID 15755582 DOI: 10.1016/J.Vaccine.2005.01.059 |
0.52 |
|
| 2005 |
MacGregor RR, Boyer JD, Ugen KE, Tebas P, Higgins TJ, Baine Y, Ciccarelli RB, Ginsberg RS, Weiner DB. Plasmid vaccination of stable HIV-positive subjects on antiviral treatment results in enhanced CD8 T-cell immunity and increased control of viral "blips". Vaccine. 23: 2066-73. PMID 15755572 DOI: 10.1016/J.Vaccine.2005.01.010 |
0.561 |
|
| 2005 |
Boyer JD, Robinson TM, Maciag PC, Peng X, Johnson RS, Pavlakis G, Lewis MG, Shen A, Siliciano R, Brown CR, Weiner DB, Paterson Y. DNA prime Listeria boost induces a cellular immune response to SIV antigens in the rhesus macaque model that is capable of limited suppression of SIV239 viral replication. Virology. 333: 88-101. PMID 15708595 DOI: 10.1016/J.Virol.2004.12.026 |
0.609 |
|
| 2005 |
Muthumani K, Hwang DS, Choo AY, Mayilvahanan S, Dayes NS, Thieu KP, Weiner DB. HIV-1 Vpr inhibits the maturation and activation of macrophages and dendritic cells in vitro. International Immunology. 17: 103-16. PMID 15611322 DOI: 10.1093/Intimm/Dxh190 |
0.397 |
|
| 2005 |
Weiner DB, Sin J. Opposite Roles of B7.1 and CD28 Costimulatory Molecules for Protective Immunity against HSV-2 Challenge in a gD DNA Vaccine Model Immune Network. 5: 68. DOI: 10.4110/In.2005.5.2.68 |
0.447 |
|
| 2005 |
Green AP, Tumanova I, Burzynski J, Rosencrance D, White J, Scheidel J, Weiner D, Boyer J. 575. In Vivo Evaluation of Supercoiled Plasmids|[ast]| Molecular Therapy. 11. DOI: 10.1016/J.Ymthe.2005.07.115 |
0.435 |
|
| 2004 |
Muthumani K, Choo AY, Hwang DS, Ugen KE, Weiner DB. HIV-1 Vpr: enhancing sensitivity of tumors to apoptosis. Current Drug Delivery. 1: 335-44. PMID 16305395 DOI: 10.2174/1567201043334614 |
0.308 |
|
| 2004 |
Kutzler MA, Weiner DB. Developing DNA vaccines that call to dendritic cells. The Journal of Clinical Investigation. 114: 1241-4. PMID 15520855 DOI: 10.1172/Jci23467 |
0.597 |
|
| 2004 |
Calarota SA, Weiner DB. Approaches for the design and evaluation of HIV-1 DNA vaccines. Expert Review of Vaccines. 3: S135-49. PMID 15285712 DOI: 10.1586/14760584.3.4.S135 |
0.578 |
|
| 2004 |
Emini EA, Weiner DB. AIDS vaccines. Expert Review of Vaccines. 3: S1-2. PMID 15285701 DOI: 10.1586/14760584.3.4.S1 |
0.398 |
|
| 2004 |
Calarota SA, Weiner DB. Enhancement of human immunodeficiency virus type 1-DNA vaccine potency through incorporation of T-helper 1 molecular adjuvants. Immunological Reviews. 199: 84-99. PMID 15233728 DOI: 10.1111/J.0105-2896.2004.00150.X |
0.625 |
|
| 2004 |
Muthumani K, Desai BM, Hwang DS, Choo AY, Laddy DJ, Thieu KP, Rao RG, Weiner DB. HIV-1 Vpr and anti-inflammatory activity. Dna and Cell Biology. 23: 239-47. PMID 15142381 DOI: 10.1089/104454904773819824 |
0.751 |
|
| 2004 |
Giri M, Ugen KE, Weiner DB. DNA vaccines against human immunodeficiency virus type 1 in the past decade. Clinical Microbiology Reviews. 17: 370-89. PMID 15084506 DOI: 10.1128/Cmr.17.2.370-389.2004 |
0.582 |
|
| 2004 |
Muthumani K, Wadsworth SA, Dayes NS, Hwang DS, Choo AY, Abeysinghe HR, Siekierka JJ, Weiner DB. Suppression of HIV-1 viral replication and cellular pathogenesis by a novel p38/JNK kinase inhibitor. Aids (London, England). 18: 739-48. PMID 15075508 DOI: 10.1097/00002030-200403260-00004 |
0.352 |
|
| 2004 |
Otero M, Calarota SA, Felber B, Laddy D, Pavlakis G, Boyer JD, Weiner DB. Resiquimod is a modest adjuvant for HIV-1 gag-based genetic immunization in a mouse model. Vaccine. 22: 1782-90. PMID 15068862 DOI: 10.1016/J.Vaccine.2004.01.037 |
0.835 |
|
| 2004 |
Chattergoon MA, Saulino V, Shames JP, Stein J, Montaner LJ, Weiner DB. Co-immunization with plasmid IL-12 generates a strong T-cell memory response in mice. Vaccine. 22: 1744-50. PMID 15068858 DOI: 10.1016/J.Vaccine.2004.01.036 |
0.792 |
|
| 2004 |
Cao C, Kutzler M, Dong H, Bai Y, Weiner DB, Ugen KE. P4-338 Immune responses elicited by mutant abeta 42 peptide in mice of different haplotypes Neurobiology of Aging. 25: S571. DOI: 10.1016/S0197-4580(04)81896-7 |
0.318 |
|
| 2004 |
Weiner DB. Vaccine: Introduction Vaccine. 22: 1589-1591. DOI: 10.1016/j.vaccine.2004.01.033 |
0.387 |
|
| 2003 |
Calarota SA, Weiner DB. Present status of human HIV vaccine development. Aids (London, England). 17: S73-84. PMID 15080183 DOI: 10.1097/00002030-200317004-00009 |
0.469 |
|
| 2003 |
Agadjanyan MG, Chattergoon MA, Holterman MJ, Monzavi-Karbassi B, Kim JJ, Dentchev T, Wilson D, Ayyavoo V, Montaner LJ, Kieber-Emmons T, Sekaly RP, Weiner DB. Costimulatory molecule immune enhancement in a plasmid vaccine model is regulated in part through the Ig constant-like domain of CD80/86. Journal of Immunology (Baltimore, Md. : 1950). 171: 4311-9. PMID 14530356 DOI: 10.4049/Jimmunol.171.8.4311 |
0.768 |
|
| 2003 |
Muthumani K, Zhang D, Dayes NS, Hwang DS, Calarota SA, Choo AY, Boyer JD, Weiner DB. Novel engineered HIV-1 East African Clade-A gp160 plasmid construct induces strong humoral and cell-mediated immune responses in vivo. Virology. 314: 134-46. PMID 14517067 DOI: 10.1016/S0042-6822(03)00459-8 |
0.5 |
|
| 2003 |
Calarota SA, Otero M, Hermanstyne K, Hermanstayne K, Lewis M, Rosati M, Felber BK, Pavlakis GN, Boyer JD, Weiner DB. Use of interleukin 15 to enhance interferon-gamma production by antigen-specific stimulated lymphocytes from rhesus macaques. Journal of Immunological Methods. 279: 55-67. PMID 12969547 DOI: 10.1016/S0022-1759(03)00246-1 |
0.433 |
|
| 2003 |
Weiner DB. Keeping the lock on smallpox. Nature Medicine. 9: 1115-6. PMID 12949522 DOI: 10.1038/Nm0903-1115 |
0.516 |
|
| 2003 |
Chattergoon MA, Shames JP, Weiner DB. Engineering cross-presentation in vivo. Expert Opinion On Biological Therapy. 3: 887-94. PMID 12943447 DOI: 10.1517/14712598.3.6.887 |
0.738 |
|
| 2003 |
Muthumani K, Choo AY, Hwang DS, Chattergoon MA, Dayes NN, Zhang D, Lee MD, Duvvuri U, Weiner DB. Mechanism of HIV-1 viral protein R-induced apoptosis. Biochemical and Biophysical Research Communications. 304: 583-92. PMID 12729593 DOI: 10.1016/S0006-291X(03)00631-4 |
0.686 |
|
| 2003 |
Monzavi-Karbassi B, Shamloo S, Kieber-Emmons M, Jousheghany F, Luo P, Lin KY, Cunto-Amesty G, Weiner DB, Kieber-Emmons T. Priming characteristics of peptide mimotopes of carbohydrate antigens. Vaccine. 21: 753-60. PMID 12531355 DOI: 10.1016/S0264-410X(02)00703-X |
0.485 |
|
| 2003 |
Muthumani K, Bagarazzi M, Conway D, Hwang DS, Manson K, Ciccarelli R, Israel Z, Montefiori DC, Ugen K, Miller N, Kim J, Boyer J, Weiner DB. A Gag-Pol/Env-Rev SIV239 DNA vaccine improves CD4 counts, and reduce viral loads after pathogenic intrarectal SIV(mac)251 challenge in rhesus Macaques. Vaccine. 21: 629-37. PMID 12531331 DOI: 10.1016/S0264-410X(02)00571-6 |
0.59 |
|
| 2003 |
Boyer JD, Kutzler MA, Chattergoon MA, Calarota SA, Pavlakis G, Sekaly RP, MacGregor RR, Weiner DB. Engineering DNA vaccination as an approach to HIV immune therapy Clinical and Applied Immunology Reviews. 3: 183-197. DOI: 10.1016/S1529-1049(02)00158-7 |
0.821 |
|
| 2002 |
Weiner DB, Kim JJ. Cancer vaccines: is the future now? Expert Review of Vaccines. 1: 257-60. PMID 12901565 DOI: 10.1586/14760584.1.3.257 |
0.457 |
|
| 2002 |
Boyer JD, Chattergoon M, Muthumani K, Kudchodkar S, Kim J, Bagarazzi M, Pavlakis G, Sekaly R, Weiner DB. Next generation DNA vaccines for HIV-1. Journal of Liposome Research. 12: 137-42. PMID 12604047 DOI: 10.1081/Lpr-120004786 |
0.802 |
|
| 2002 |
Baumeister MA, Chattergoon MA, Weiner DB. Prospects for an HIV vaccine: conventional approaches and DNA immunization. Biotechnology & Genetic Engineering Reviews. 19: 205-42. PMID 12520879 DOI: 10.1080/02648725.2002.10648030 |
0.783 |
|
| 2002 |
MacGregor RR, Ginsberg R, Ugen KE, Baine Y, Kang CU, Tu XM, Higgins T, Weiner DB, Boyer JD. T-cell responses induced in normal volunteers immunized with a DNA-based vaccine containing HIV-1 env and rev. Aids (London, England). 16: 2137-43. PMID 12409734 DOI: 10.1097/00002030-200211080-00005 |
0.595 |
|
| 2002 |
Muthumani K, Hwang DS, Dayes NS, Kim JJ, Weiner DB. The HIV-1 accessory gene vpr can inhibit antigen-specific immune function. Dna and Cell Biology. 21: 689-95. PMID 12396612 DOI: 10.1089/104454902760330237 |
0.445 |
|
| 2002 |
Gómez-Román VR, Cao C, Bai Y, SantamarÃa H, Acero G, Manoutcharian K, Weiner DB, Ugen KE, Gevorkian G. Phage-displayed mimotopes recognizing a biologically active anti-HIV-1 gp120 murine monoclonal antibody. Journal of Acquired Immune Deficiency Syndromes (1999). 31: 147-53. PMID 12394792 DOI: 10.1097/00126334-200210010-00004 |
0.391 |
|
| 2002 |
Muthumani K, Bagarazzi M, Conway D, Hwang DS, Ayyavoo V, Zhang D, Manson K, Kim J, Boyer J, Weiner DB. Inclusion of Vpr accessory gene in a plasmid vaccine cocktail markedly reduces Nef vaccine effectiveness in vivo resulting in CD4 cell loss and increased viral loads in rhesus macaques. Journal of Medical Primatology. 31: 179-85. PMID 12390540 DOI: 10.1034/J.1600-0684.2002.02004.X |
0.587 |
|
| 2002 |
Ramanathan MP, Curley E, Su M, Chambers JA, Weiner DB. Carboxyl terminus of hVIP/mov34 is critical for HIV-1-Vpr interaction and glucocorticoid-mediated signaling. The Journal of Biological Chemistry. 277: 47854-60. PMID 12237292 DOI: 10.1074/Jbc.M203905200 |
0.323 |
|
| 2002 |
Muthumani K, Zhang D, Hwang DS, Kudchodkar S, Dayes NS, Desai BM, Malik AS, Yang JS, Chattergoon MA, Maguire HC, Weiner DB. Adenovirus encoding HIV-1 Vpr activates caspase 9 and induces apoptotic cell death in both p53 positive and negative human tumor cell lines. Oncogene. 21: 4613-25. PMID 12096338 DOI: 10.1038/Sj.Onc.1205549 |
0.661 |
|
| 2002 |
Muthumani K, Hwang DS, Desai BM, Zhang D, Dayes N, Green DR, Weiner DB. HIV-1 Vpr induces apoptosis through caspase 9 in T cells and peripheral blood mononuclear cells. The Journal of Biological Chemistry. 277: 37820-31. PMID 12095993 DOI: 10.1074/Jbc.M205313200 |
0.331 |
|
| 2002 |
Chattergoon MA, Maguire HH, Robinson TM, Serrano E, Boyer JD, Weiner DB. Plasmid immunization primes unique DTH responses to HIV-1MN envelope epitopes as compared to recombinant protein vaccination. Hybridoma and Hybridomics. 21: 117-22. PMID 12031101 DOI: 10.1089/153685902317401717 |
0.773 |
|
| 2002 |
Muthumani K, Kudchodkar S, Zhang D, Bagarazzi ML, Kim JJ, Boyer JD, Ayyavoo V, Pavlakis GN, Weiner DB. Issues for improving multiplasmid DNA vaccines for HIV-1. Vaccine. 20: 1999-2003. PMID 11983262 DOI: 10.1016/S0264-410X(02)00086-5 |
0.593 |
|
| 2002 |
Boyer JD, Nath B, Schumann K, Curley E, Manson K, Kim J, Weiner DB. IL-4 increases Simian immunodeficiency virus replication despite enhanced SIV immune responses in infected rhesus macaques. International Journal For Parasitology. 32: 543-50. PMID 11943227 DOI: 10.1016/S0020-7519(01)00355-1 |
0.476 |
|
| 2002 |
Chattergoon M, Weiner D. Plasmid DNA: Is there a toll on the way to apoptosis? Journal of Gene Medicine. 4: 25-26. PMID 11828384 DOI: 10.1002/Jgm.238 |
0.674 |
|
| 2002 |
Ayyavoo V, Muthumani K, Kudchodkar S, Zhang D, Ramanathan P, Dayes NS, Kim JJ, Sin JI, Montaner LJ, Weiner DB. HIV-1 viral protein R compromises cellular immune function in vivo. International Immunology. 14: 13-22. PMID 11751747 DOI: 10.1093/Intimm/14.1.13 |
0.574 |
|
| 2001 |
Dickey CA, Morgan DG, Kudchodkar S, Weiner DB, Bai Y, Cao C, Gordon MN, Ugen KE. Duration and specificity of humoral immune responses in mice vaccinated with the Alzheimer's disease-associated beta-amyloid 1-42 peptide. Dna and Cell Biology. 20: 723-9. PMID 11788050 DOI: 10.1089/10445490152717587 |
0.447 |
|
| 2001 |
Vanitharani R, Mahalingam S, Rafaeli Y, Singh SP, Srinivasan A, Weiner DB, Ayyavoo V. HIV-1 Vpr transactivates LTR-directed expression through sequences present within -278 to -176 and increases virus replication in vitro. Virology. 289: 334-42. PMID 11689055 DOI: 10.1006/Viro.2001.1153 |
0.339 |
|
| 2001 |
Yang JS, Kim JJ, Hwang D, Choo AY, Dang K, Maguire H, Kudchodkar S, Ramanathan MP, Weiner DB. Induction of potent Th1-type immune responses from a novel DNA vaccine for West Nile virus New York isolate (WNV-NY1999). The Journal of Infectious Diseases. 184: 809-16. PMID 11550123 DOI: 10.1086/323395 |
0.513 |
|
| 2001 |
Kim JJ, Yang JS, Nottingham LK, Tang W, Dang K, Manson KH, Wyand MS, Wilson DM, Weiner DB. Induction of immune responses and safety profiles in rhesus macaques immunized with a DNA vaccine expressing human prostate specific antigen. Oncogene. 20: 4497-506. PMID 11494145 DOI: 10.1038/Sj.Onc.1204542 |
0.577 |
|
| 2001 |
Kim JJ, Yang JS, Nottingham LK, Lee DJ, Lee M, Manson KH, Wyand MS, Boyer JD, Ugen KE, Weiner DB. Protection from immunodeficiency virus challenges in rhesus macaques by multicomponent DNA immunization. Virology. 285: 204-17. PMID 11437655 DOI: 10.1006/Viro.2001.0958 |
0.588 |
|
| 2001 |
Sin JI, Kim JJ, Zhang D, Weiner DB. Modulation of cellular responses by plasmid CD40L: CD40L plasmid vectors enhance antigen-specific helper T cell type 1 CD4+ T cell-mediated protective immunity against herpes simplex virus type 2 in vivo. Human Gene Therapy. 12: 1091-102. PMID 11399230 DOI: 10.1089/104303401750214302 |
0.503 |
|
| 2001 |
Kim JJ, Yang JS, Dang K, Manson KH, Weiner DB. Engineering enhancement of immune responses to DNA-based vaccines in a prostate cancer model in rhesus macaques through the use of cytokine gene adjuvants. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 7: 882s-889s. PMID 11300487 |
0.449 |
|
| 2001 |
Kim JJ, Yang JS, Manson KH, Weiner DB. Modulation of antigen-specific cellular immune responses to DNA vaccination in rhesus macaques through the use of IL-2, IFN-gamma, or IL-4 gene adjuvants. Vaccine. 19: 2496-505. PMID 11257383 DOI: 10.1016/S0264-410X(00)00479-5 |
0.609 |
|
| 2001 |
Ramanathan MP, Ayyavoo V, Weiner DB. Choice of expression vector alters the localization of a human cellular protein. Dna and Cell Biology. 20: 101-5. PMID 11244567 DOI: 10.1089/104454901750070300 |
0.322 |
|
| 2001 |
Fernando KP, Muthumani K, Zhang D, Kudchodkar S, Weiner DB. HIV DNA Vaccination: Advances and Experiences Bundesgesundheitsblatt - Gesundheitsforschung - Gesundheitsschutz. 44: 1076-1082. DOI: 10.1007/S00103-001-0291-1 |
0.574 |
|
| 2000 |
Godillot AP, Fang Q, Higgins T, Pachuk C, Boyer J, Weiner DB, Lessin S, Williams WV. Genetic vaccination targeting T-cell receptors. Methods in Molecular Medicine. 29: 375-95. PMID 21374336 DOI: 10.1385/1-59259-688-6:375 |
0.37 |
|
| 2000 |
Kim JJ, Weiner DB. Optimization of DNA vaccines through the use of molecular adjuvants. Methods in Molecular Medicine. 29: 205-20. PMID 21374322 DOI: 10.1385/1-59259-688-6:205 |
0.576 |
|
| 2000 |
Sin JI, Kim J, Chattergoon M, Ayyavoo V, McCallus D, Ugen KE, Boyer JD, Weiner DB. Engineering of DNA vaccines using molecular adjuvant plasmids. Developments in Biologicals. 104: 187-98. PMID 11713819 |
0.761 |
|
| 2000 |
Sin JI, Weiner DB. Improving DNA vaccines targeting viral infection. Intervirology. 43: 233-46. PMID 11251379 DOI: 10.1159/000053991 |
0.534 |
|
| 2000 |
Pachuk CJ, McCallus DE, Weiner DB, Satishchandran C. DNA vaccines--challenges in delivery. Current Opinion in Molecular Therapeutics. 2: 188-98. PMID 11249641 |
0.492 |
|
| 2000 |
Shedlock DJ, Weiner DB. DNA vaccination: antigen presentation and the induction of immunity. Journal of Leukocyte Biology. 68: 793-806. PMID 11129646 DOI: 10.1189/Jlb.68.6.793 |
0.598 |
|
| 2000 |
Sin J, Kim JJ, Pachuk C, Satishchandran C, Weiner DB. DNA vaccines encoding interleukin-8 and RANTES enhance antigen-specific Th1-type CD4(+) T-cell-mediated protective immunity against herpes simplex virus type 2 in vivo. Journal of Virology. 74: 11173-80. PMID 11070014 DOI: 10.1128/Jvi.74.23.11173-11180.2000 |
0.556 |
|
| 2000 |
Pachuk CJ, Ciccarelli RB, Samuel M, Bayer ME, Troutman RD, Zurawski DV, Schauer JI, Higgins TJ, Weiner DB, Sosnoski DM, Zurawski VR, Satishchandran C. Characterization of a new class of DNA delivery complexes formed by the local anesthetic bupivacaine. Biochimica Et Biophysica Acta. 1468: 20-30. PMID 11018648 DOI: 10.1016/S0005-2736(00)00242-X |
0.409 |
|
| 2000 |
Weiner D. Plasmid interleukin 12. Aids. 14: 1759-1760. PMID 10985312 DOI: 10.1097/00002030-200008180-00010 |
0.32 |
|
| 2000 |
Boyer JD, Cohen AD, Ugen KE, Edgeworth RL, Bennett M, Shah A, Schumann K, Nath B, Javadian A, Bagarazzi ML, Kim J, Weiner DB. Therapeutic immunization of HIV-infected chimpanzees using HIV-1 plasmid antigens and interleukin-12 expressing plasmids. Aids (London, England). 14: 1515-22. PMID 10983638 DOI: 10.1097/00002030-200007280-00007 |
0.544 |
|
| 2000 |
Sin JI, Kim J, Pachuk C, Weiner DB, Patchuk C. Interleukin 7 can enhance antigen-specific cytotoxic-T-lymphocyte and/or Th2-type immune responses in vivo. Clinical and Diagnostic Laboratory Immunology. 7: 751-8. PMID 10973449 DOI: 10.1128/Cdli.7.5.751-758.2000 |
0.363 |
|
| 2000 |
Chattergoon MA, Kim JJ, Yang JS, Robinson TM, Lee DJ, Dentchev T, Wilson DM, Ayyavoo V, Weiner DB. Targeted antigen delivery to antigen-presenting cells including dendritic cells by engineered Fas-mediated apoptosis. Nature Biotechnology. 18: 974-9. PMID 10973219 DOI: 10.1038/79470 |
0.745 |
|
| 2000 |
Sin JI, Kim J, Dang K, Lee D, Pachuk C, Satishchandran C, Weiner DB, Patchuk C. LFA-3 plasmid DNA enhances Ag-specific humoral- and cellular-mediated protective immunity against herpes simplex virus-2 in vivo: involvement of CD4+ T cells in protection. Cellular Immunology. 203: 19-28. PMID 10915558 DOI: 10.1006/Cimm.2000.1667 |
0.519 |
|
| 2000 |
Kieber-Emmons T, Monzavi-Karbassi B, Wang B, Luo P, Weiner DB. Cutting edge: DNA immunization with minigenes of carbohydrate mimotopes induce functional anti-carbohydrate antibody response. Journal of Immunology (Baltimore, Md. : 1950). 165: 623-7. PMID 10878332 DOI: 10.4049/Jimmunol.165.2.623 |
0.536 |
|
| 2000 |
Kim JJ, Yang JS, Dentchev T, Dang K, Weiner DB. Chemokine gene adjuvants can modulate immune responses induced by DNA vaccines. Journal of Interferon & Cytokine Research : the Official Journal of the International Society For Interferon and Cytokine Research. 20: 487-98. PMID 10841077 DOI: 10.1089/10799900050023906 |
0.439 |
|
| 2000 |
Dickey C, Ziegner U, Agadjanyan MG, Srikantan V, Refaeli Y, Prabhu A, Sato A, Williams WV, Weiner DB, Ugen KE. Murine monoclonal antibodies biologically active against the amino region of HIV-1 gp120: isolation and characterization. Dna and Cell Biology. 19: 243-52. PMID 10798448 DOI: 10.1089/104454900314519 |
0.382 |
|
| 2000 |
Kim JJ, Yang JS, Montaner L, Lee DJ, Chalian AA, Weiner DB. Coimmunization with IFN-gamma or IL-2, but not IL-13 or IL-4 cDNA can enhance Th1-type DNA vaccine-induced immune responses in vivo. Journal of Interferon & Cytokine Research : the Official Journal of the International Society For Interferon and Cytokine Research. 20: 311-9. PMID 10762079 DOI: 10.1089/107999000312450 |
0.416 |
|
| 2000 |
Muthumani K, Montaner LJ, Ayyavoo V, Weiner DB. Vpr-GFP virion particle identifies HIV-infected targets and preserves HIV-1Vpr function in macrophages and T-cells. Dna and Cell Biology. 19: 179-88. PMID 10749170 DOI: 10.1089/104454900314564 |
0.362 |
|
| 2000 |
Ayyavoo V, Kudchodkar S, Ramanathan MP, Le P, Muthumani K, Megalai NM, Dentchev T, Santiago-Barrios L, Mrinalini C, Weiner DB. Immunogenicity of a novel DNA vaccine cassette expressing multiple human immunodeficiency virus (HIV-1) accessory genes. Aids (London, England). 14: 1-9. PMID 10714562 DOI: 10.1097/00002030-200001070-00001 |
0.536 |
|
| 2000 |
Kim JJ, Yang JS, VanCott TC, Lee DJ, Manson KH, Wyand MS, Boyer JD, Ugen KE, Weiner DB. Modulation of antigen-specific humoral responses in rhesus macaques by using cytokine cDNAs as DNA vaccine adjuvants. Journal of Virology. 74: 3427-9. PMID 10708463 DOI: 10.1128/Jvi.74.7.3427-3429.2000 |
0.587 |
|
| 2000 |
Kim JJ, Yang JS, Lee DJ, Wilson DM, Nottingham LK, Morrison L, Tsai A, Oh J, Dang K, Dentchev T, Agadjanyan MG, Sin JI, Chalian AA, Weiner DB. Macrophage colony-stimulating factor can modulate immune responses and attract dendritic cells in vivo. Human Gene Therapy. 11: 305-21. PMID 10680844 DOI: 10.1089/10430340050016049 |
0.571 |
|
| 2000 |
Boyer JD, Cohen AD, Vogt S, Schumann K, Nath B, Ahn L, Lacy K, Bagarazzi ML, Higgins TJ, Baine Y, Ciccarelli RB, Ginsberg RS, MacGregor RR, Weiner DB. Vaccination of seronegative volunteers with a human immunodeficiency virus type 1 env/rev DNA vaccine induces antigen-specific proliferation and lymphocyte production of beta-chemokines. The Journal of Infectious Diseases. 181: 476-83. PMID 10669329 DOI: 10.1086/315229 |
0.582 |
|
| 2000 |
MacGregor RR, Boyer JD, Ciccarelli RB, Ginsberg RS, Weiner DB. Safety and immune responses to a DNA-based human immunodeficiency virus (HIV) type I env/rev vaccine in HIV-infected recipients: follow-up data. The Journal of Infectious Diseases. 181: 406. PMID 10608800 DOI: 10.1086/315199 |
0.505 |
|
| 2000 |
Kang CU, Weiner DB, Boyer JD. Genetic immunisation and treatment of disease Expert Opinion On Therapeutic Patents. 10: 1345-1355. DOI: 10.1517/13543776.10.9.1345 |
0.512 |
|
| 2000 |
Muthumani K, Kudchodkar S, Papasavvas E, Montaner LJ, Weiner DB, Ayyavoo V. HIV-1 Vpr regulates expression of β chemokines in human primary lymphocytes and macrophages Journal of Leukocyte Biology. 68: 366-372. DOI: 10.1189/Jlb.68.3.366 |
0.356 |
|
| 1999 |
Kim JJ, Weiner DB. Development of multicomponent DNA vaccination strategies against HIV. Current Opinion in Molecular Therapeutics. 1: 43-9. PMID 11249683 |
0.412 |
|
| 1999 |
Kim JJ, Nottingham LK, Tsai A, Lee DJ, Maguire HC, Oh J, Dentchev T, Manson KH, Wyand MS, Agadjanyan MG, Ugen KE, Weiner DB. Antigen-specific humoral and cellular immune responses can be modulated in rhesus macaques through the use of IFN-gamma, IL-12, or IL-18 gene adjuvants. Journal of Medical Primatology. 28: 214-23. PMID 10593488 DOI: 10.1111/J.1600-0684.1999.Tb00272.X |
0.546 |
|
| 1999 |
Sin JI, Ayyavoo V, Boyer J, Kim J, Ciccarelli RB, Weiner DB. Protective immune correlates can segregate by vaccine type in a murine herpes model system. International Immunology. 11: 1763-73. PMID 10545480 DOI: 10.1093/Intimm/11.11.1763 |
0.568 |
|
| 1999 |
Sin JI, Bagarazzi M, Pachuk C, Weiner DB. DNA priming-protein boosting enhances both antigen-specific antibody and Th1-type cellular immune responses in a murine herpes simplex virus-2 gD vaccine model. Dna and Cell Biology. 18: 771-9. PMID 10541436 DOI: 10.1089/104454999314917 |
0.574 |
|
| 1999 |
Boyer JD, Kim J, Ugen K, Cohen AD, Ahn L, Schumann K, Lacy K, Bagarazzi ML, Javadian A, Ciccarelli RB, Ginsberg RS, MacGregor RR, Weiner DB. HIV-1 DNA vaccines and chemokines. Vaccine. 17: S53-64. PMID 10506409 DOI: 10.1016/S0264-410X(99)00235-2 |
0.594 |
|
| 1999 |
Bagarazzi ML, Boyer JD, Javadian MA, Chattergoon MA, Shah AR, Cohen AD, Bennett MK, Ciccarelli RB, Ugen KE, Weiner DB. Systemic and mucosal immunity is elicited after both intramuscular and intravaginal delivery of human immunodeficiency virus type 1 DNA plasmid vaccines to pregnant chimpanzees. The Journal of Infectious Diseases. 180: 1351-5. PMID 10479171 DOI: 10.1086/314978 |
0.801 |
|
| 1999 |
Weiner DB, Kennedy RC. Genetic vaccines. Scientific American. 281: 50-7. PMID 10396782 |
0.339 |
|
| 1999 |
Kim JJ, Tsai A, Nottingham LK, Morrison L, Cunning DM, Oh J, Lee DJ, Dang K, Dentchev T, Chalian AA, Agadjanyan MG, Weiner DB. Intracellular adhesion molecule-1 modulates beta-chemokines and directly costimulates T cells in vivo. The Journal of Clinical Investigation. 103: 869-77. PMID 10079108 DOI: 10.1172/Jci6024 |
0.42 |
|
| 1999 |
Sin JI, Kim JJ, Arnold RL, Shroff KE, McCallus D, Pachuk C, McElhiney SP, Wolf MW, Pompa-de Bruin SJ, Higgins TJ, Ciccarelli RB, Weiner DB. IL-12 gene as a DNA vaccine adjuvant in a herpes mouse model: IL-12 enhances Th1-type CD4+ T cell-mediated protective immunity against herpes simplex virus-2 challenge. Journal of Immunology (Baltimore, Md. : 1950). 162: 2912-21. PMID 10072541 |
0.443 |
|
| 1999 |
Kim JJ, Simbiri KA, Sin JI, Dang K, Oh J, Dentchev T, Lee D, Nottingham LK, Chalian AA, McCallus D, Ciccarelli R, Agadjanyan MG, Weiner DB. Cytokine molecular adjuvants modulate immune responses induced by DNA vaccine constructs for HIV-1 and SIV. Journal of Interferon & Cytokine Research : the Official Journal of the International Society For Interferon and Cytokine Research. 19: 77-84. PMID 10048771 DOI: 10.1089/107999099314441 |
0.557 |
|
| 1999 |
Boyer JD, Chattergoon MA, Ugen KE, Shah A, Bennett M, Cohen A, Nyland S, Lacy KE, Bagarazzi ML, Higgins TJ, Baine Y, Ciccarelli RB, Ginsberg RS, MacGregor RR, Weiner DB. Enhancement of cellular immune response in HIV-1 seropositive individuals: A DNA-based trial. Clinical Immunology (Orlando, Fla.). 90: 100-7. PMID 9884357 DOI: 10.1006/Clim.1998.4616 |
0.762 |
|
| 1999 |
Sin JI, Kim JJ, Boyer JD, Ciccarelli RB, Higgins TJ, Weiner DB. In vivo modulation of vaccine-induced immune responses toward a Th1 phenotype increases potency and vaccine effectiveness in a herpes simplex virus type 2 mouse model. Journal of Virology. 73: 501-9. PMID 9847356 DOI: 10.1128/Jvi.73.1.501-509.1999 |
0.563 |
|
| 1999 |
Conway DH, Lischner HW, Boyer J, Schumann K, Weiner DB, Bagarazzi ML. Lymphoproliferative Responses to HIV-Specific Antigens in the HIV-Infected Pediatric Patient Pediatric Research. 45: 9A-9A. DOI: 10.1203/00006450-199904020-00061 |
0.344 |
|
| 1998 |
Kim JJ, Trivedi NN, Wilson DM, Mahalingam S, Morrison L, Tsai A, Chattergoon MA, Dang K, Patel M, Ahn L, Boyer JD, Chalian AA, Schoemaker H, Kieber-Emmons T, Agadjanyan MA, ... Weiner DB, et al. Molecular and immunological analysis of genetic prostate specific antigen (PSA) vaccine. Oncogene. 17: 3125-35. PMID 9872328 DOI: 10.1038/Sj.Onc.1201736 |
0.771 |
|
| 1998 |
Boyer JD, Chattergoon M, Shah A, Ginsberg R, MacGregor RR, Weiner DB. HIV-1 DNA based vaccine induces a CD8 mediated cross-clade CTL response. Developments in Biological Standardization. 95: 147-53. PMID 9855425 |
0.784 |
|
| 1998 |
Sin JI, Kim JJ, Ugen KE, Ciccarelli RB, Higgins TJ, Weiner DB. Enhancement of protective humoral (Th2) and cell-mediated (Th1) immune responses against herpes simplex virus-2 through co-delivery of granulocyte-macrophage colony-stimulating factor expression cassettes. European Journal of Immunology. 28: 3530-40. PMID 9842896 DOI: 10.1002/(Sici)1521-4141(199811)28:11<3530::Aid-Immu3530>3.0.Co;2-C |
0.561 |
|
| 1998 |
Cohen AD, Boyer JD, Weiner DB. Modulating the immune response to genetic immunization. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 12: 1611-26. PMID 9837851 DOI: 10.1096/Fasebj.12.15.1611 |
0.568 |
|
| 1998 |
Ayyavoo V, Nagashunmugam T, Phung MT, Buckner C, Kudckodkar S, Le P, Reddy PJ, Santiago L, Patel M, Tea L, Weiner DB. Construction of attenuated HIV-1 accessory gene immunization cassettes. Vaccine. 16: 1872-9. PMID 9795395 DOI: 10.1016/S0264-410X(98)00172-8 |
0.549 |
|
| 1998 |
Bagarazzi ML, Boyer JD, Ugen KE, Javadian MA, Chattergoon M, Shah A, Bennett M, Ciccarelli R, Carrano R, Coney L, Weiner DB. Safety and immunogenicity of HIV-1 DNA constructs in chimpanzees. Vaccine. 16: 1836-41. PMID 9795389 DOI: 10.1016/S0264-410X(98)00178-9 |
0.788 |
|
| 1998 |
Kim JJ, Nottingham LK, Wilson DM, Bagarazzi ML, Tsai A, Morrison LD, Javadian A, Chalian AA, Agadjanyan MG, Weiner DB. Engineering DNA vaccines via co-delivery of co-stimulatory molecule genes. Vaccine. 16: 1828-35. PMID 9795388 DOI: 10.1016/S0264-410X(98)00177-7 |
0.616 |
|
| 1998 |
Ugen KE, Nyland SB, Boyer JD, Vidal C, Lera L, Rasheid S, Chattergoon M, Bagarazzi ML, Ciccarelli R, Higgins T, Baine Y, Ginsberg R, Macgregor RR, Weiner DB. DNA vaccination with HIV-1 expressing constructs elicits immune responses in humans. Vaccine. 16: 1818-21. PMID 9795386 DOI: 10.1016/S0264-410X(98)00180-7 |
0.769 |
|
| 1998 |
Kim JJ, Nottingham LK, Sin JI, Tsai A, Morrison L, Oh J, Dang K, Hu Y, Kazahaya K, Bennett M, Dentchev T, Wilson DM, Chalian AA, Boyer JD, Agadjanyan MG, ... Weiner DB, et al. CD8 positive T cells influence antigen-specific immune responses through the expression of chemokines. The Journal of Clinical Investigation. 102: 1112-24. PMID 9739045 DOI: 10.1172/Jci3986 |
0.466 |
|
| 1998 |
Kim JJ, Maguire HC, Nottingham LK, Morrison LD, Tsai A, Sin JI, Chalian AA, Weiner DB. Coadministration of IL-12 or IL-10 expression cassettes drives immune responses toward a Th1 phenotype. Journal of Interferon & Cytokine Research : the Official Journal of the International Society For Interferon and Cytokine Research. 18: 537-47. PMID 9712370 DOI: 10.1089/Jir.1998.18.537 |
0.43 |
|
| 1998 |
MacGregor RR, Boyer JD, Ugen KE, Lacy KE, Gluckman SJ, Bagarazzi ML, Chattergoon MA, Baine Y, Higgins TJ, Ciccarelli RB, Coney LR, Ginsberg RS, Weiner DB. First human trial of a DNA-based vaccine for treatment of human immunodeficiency virus type 1 infection: safety and host response. The Journal of Infectious Diseases. 178: 92-100. PMID 9652427 DOI: 10.1086/515613 |
0.791 |
|
| 1998 |
Chattergoon MA, Robinson TM, Boyer JD, Weiner DB. Specific immune induction following DNA-based immunization through in vivo transfection and activation of macrophages/antigen-presenting cells. Journal of Immunology (Baltimore, Md. : 1950). 160: 5707-18. PMID 9637479 |
0.729 |
|
| 1998 |
Boyer J, Ugen K, Wang B, Chattergoon M, Tsai A, Merva M, Weiner DB. Induction of a TH1 type cellular immune response to the human immunodeficiency type 1 virus by in vivo DNA inoculation. Developments in Biological Standardization. 92: 169-74. PMID 9554272 |
0.756 |
|
| 1998 |
Kim JJ, Trivedi NN, Nottingham LK, Morrison L, Tsai A, Hu Y, Mahalingam S, Dang K, Ahn L, Doyle NK, Wilson DM, Chattergoon MA, Chalian AA, Boyer JD, Agadjanyan MG, ... Weiner DB, et al. Modulation of amplitude and direction of in vivo immune responses by co-administration of cytokine gene expression cassettes with DNA immunogens. European Journal of Immunology. 28: 1089-103. PMID 9541605 DOI: 10.1002/(Sici)1521-4141(199803)28:03<1089::Aid-Immu1089>3.0.Co;2-L |
0.733 |
|
| 1998 |
Agadjanyan MG, Chattergoon MA, Petrushina I, Bennett M, Kim J, Ugen KE, Kieber-Emmons T, Weiner DB. Monoclonal antibodies define a cellular antigen involved in HTLV-I infection. Hybridoma. 17: 9-19. PMID 9523233 DOI: 10.1089/Hyb.1998.17.9 |
0.68 |
|
| 1998 |
Mahalingam S, Ayyavoo V, Patel M, Kieber-Emmons T, Kao GD, Muschel RJ, Weiner DB. HIV-1 Vpr interacts with a human 34-kDa mov34 homologue, a cellular factor linked to the G2/M phase transition of the mammalian cell cycle. Proceedings of the National Academy of Sciences of the United States of America. 95: 3419-24. PMID 9520381 DOI: 10.1073/Pnas.95.7.3419 |
0.332 |
|
| 1998 |
Agadjanyan MG, Wang B, Nyland SB, Weiner DB, Ugen KE. DNA plasmid based vaccination against the oncogenic human T cell leukemia virus type 1. Current Topics in Microbiology and Immunology. 226: 175-92. PMID 9479842 DOI: 10.1007/978-3-642-80475-5_11 |
0.501 |
|
| 1998 |
Bagarazzi ML, Boyer JD, Ayyavoo V, Weiner DB. Nucleic acid-based vaccines as an approach to immunization against human immunodeficiency virus type-1. Current Topics in Microbiology and Immunology. 226: 107-43. PMID 9479839 DOI: 10.1007/978-3-642-80475-5_8 |
0.494 |
|
| 1998 |
Wang B, Godillot AP, Madaio MP, Weiner DB, Williams WV. Vaccination against pathogenic cells by DNA inoculation. Current Topics in Microbiology and Immunology. 226: 21-35. PMID 9479833 DOI: 10.1007/978-3-642-80475-5_2 |
0.57 |
|
| 1998 |
Koprowski H, Weiner DB. DNA vaccination/genetic vaccination. Current Topics in Microbiology and Immunology. 226: V-XIII. PMID 9479831 DOI: 10.1007/978-3-642-80475-5 |
0.59 |
|
| 1997 |
Agadjanyan MG, Trivedi NN, Kudchodkar S, Bennett M, Levine W, Lin A, Boyer J, Levy D, Ugen KE, Kim JJ, Weiner DB. An HIV type 2 DNA vaccine induces cross-reactive immune responses against HIV type 2 and SIV. Aids Research and Human Retroviruses. 13: 1561-72. PMID 9430248 DOI: 10.1089/Aid.1997.13.1561 |
0.511 |
|
| 1997 |
Kim JJ, Weiner DB. DNA gene vaccination for HIV. Springer Seminars in Immunopathology. 19: 175-94. PMID 9406345 DOI: 10.1007/BF00870267 |
0.504 |
|
| 1997 |
Boyer JD, Ugen KE, Chattergoon M, Wang B, Shah A, Agadjanyan M, Bagarazzi ML, Javadian A, Carrano R, Coney L, Williams WV, Weiner DB. DNA vaccination as anti-human immunodeficiency virus immunotherapy in infected chimpanzees. The Journal of Infectious Diseases. 176: 1501-9. PMID 9395361 DOI: 10.1086/514148 |
0.793 |
|
| 1997 |
Ayyavoo V, Nagashunmugam T, Boyer J, Mahalingam S, Fernandes LS, Le P, Lin J, Nguyen C, Chattargoon M, Goedert JJ, Friedman H, Weiner DB. Development of genetic vaccines for pathogenic genes: construction of attenuated vif DNA immunization cassettes. Aids (London, England). 11: 1433-44. PMID 9342065 DOI: 10.1097/00002030-199712000-00007 |
0.52 |
|
| 1997 |
Ayyavoo V, Mahboubi A, Mahalingam S, Ramalingam R, Kudchodkar S, Williams WV, Green DR, Weiner DB. HIV-1 Vpr suppresses immune activation and apoptosis through regulation of nuclear factor kappa B. Nature Medicine. 3: 1117-23. PMID 9334723 DOI: 10.1038/Nm1097-1117 |
0.337 |
|
| 1997 |
Chattergoon M, Boyer J, Weiner DB. Genetic immunization: a new era in vaccines and immune therapeutics. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 11: 753-63. PMID 9271360 DOI: 10.1096/Fasebj.11.10.9271360 |
0.784 |
|
| 1997 |
Bagarazzi ML, Boyer JD, Javadian MA, Chattergoon M, Dang K, Kim G, Shah J, Wang B, Weiner DB. Safety and immunogenicity of intramuscular and intravaginal delivery of HIV-1 DNA constructs to infant chimpanzees. Journal of Medical Primatology. 26: 27-33. PMID 9271186 DOI: 10.1111/J.1600-0684.1997.Tb00316.X |
0.768 |
|
| 1997 |
Ayyavoo V, Rafaeli Y, Nagashunmugam T, Mahalingham S, Phung MT, Hamam A, Williams WV, Weiner DB. HIV-1 viral protein R (Vpr) as a regulator of the target cell. Psychoneuroendocrinology. 22: S41-9. PMID 9264146 DOI: 10.1016/S0306-4530(97)00018-8 |
0.359 |
|
| 1997 |
Ugen KE, Boyer JD, Wang B, Bagarazzi M, Javadian A, Frost P, Merva MM, Agadjanyan MG, Nyland S, Williams WV, Coney L, Ciccarelli R, Weiner DB. Nucleic acid immunization of chimpanzees as a prophylactic/immunotherapeutic vaccination model for HIV-1: prelude to a clinical trial. Vaccine. 15: 927-30. PMID 9234550 DOI: 10.1016/S0264-410X(96)00254-X |
0.553 |
|
| 1997 |
Kim JJ, Ayyavoo V, Bagarazzi ML, Chattergoon M, Boyer JD, Wang B, Weiner DB. Development of a multicomponent candidate vaccine for HIV-1. Vaccine. 15: 879-83. PMID 9234538 DOI: 10.1016/S0264-410X(96)00260-5 |
0.818 |
|
| 1997 |
Wang B, Dang K, Agadjanyan MG, Srikantan V, Li F, Ugen KE, Boyer J, Merva M, Williams WV, Weiner DB. Mucosal immunization with a DNA vaccine induces immune responses against HIV-1 at a mucosal site. Vaccine. 15: 821-5. PMID 9234524 DOI: 10.1016/S0264-410X(96)00259-9 |
0.584 |
|
| 1997 |
Ayyavoo V, Mahalingam S, Rafaeli Y, Kudchodkar S, Chang D, Nagashunmugam T, Williams WV, Weiner DB. HIV-1 viral protein R (Vpr) regulates viral replication and cellular proliferation in T cells and monocytoid cells in vitro. Journal of Leukocyte Biology. 62: 93-9. PMID 9225999 DOI: 10.1002/Jlb.62.1.93 |
0.361 |
|
| 1997 |
Kim JJ, Bagarazzi ML, Trivedi N, Hu Y, Kazahaya K, Wilson DM, Ciccarelli R, Chattergoon MA, Dang K, Mahalingam S, Chalian AA, Agadjanyan MG, Boyer JD, Wang B, Weiner DB. Engineering of in vivo immune responses to DNA immunization via codelivery of costimulatory molecule genes. Nature Biotechnology. 15: 641-6. PMID 9219266 DOI: 10.1038/Nbt0797-641 |
0.786 |
|
| 1997 |
Agadjanyan M, Luo P, Westerink MA, Carey LA, Hutchins W, Steplewski Z, Weiner DB, Kieber-Emmons T. Peptide mimicry of carbohydrate epitopes on human immunodeficiency virus. Nature Biotechnology. 15: 547-51. PMID 9181577 DOI: 10.1038/Nbt0697-547 |
0.416 |
|
| 1997 |
Yusibov V, Modelska A, Steplewski K, Agadjanyan M, Weiner D, Hooper DC, Koprowski H. Antigens produced in plants by infection with chimeric plant viruses immunize against rabies virus and HIV-1 Proceedings of the National Academy of Sciences of the United States of America. 94: 5784-5788. PMID 9159151 DOI: 10.1073/Pnas.94.11.5784 |
0.404 |
|
| 1997 |
Boyer JD, Ugen KE, Wang B, Agadjanyan M, Gilbert L, Bagarazzi ML, Chattergoon M, Frost P, Javadian A, Williams WV, Refaeli Y, Ciccarelli RB, McCallus D, Coney L, Weiner DB. Protection of chimpanzees from high-dose heterologous HIV-1 challenge by DNA vaccination. Nature Medicine. 3: 526-32. PMID 9142121 DOI: 10.1038/Nm0597-526 |
0.8 |
|
| 1997 |
Mahalingam S, MacDonald B, Ugen KE, Ayyavoo V, Agadjanyan MG, Williams WV, Weiner DB. In vitro and in vivo tumor growth suppression by HIV-1 Vpr. Dna and Cell Biology. 16: 137-43. PMID 9052734 DOI: 10.1089/Dna.1997.16.137 |
0.322 |
|
| 1997 |
Zhang X, Gaubin M, Briant L, Srikantan V, Murali R, Saragovi U, Weiner D, Devaux C, Autiero M, Piatier-Tonneau D, Greene MI. Synthetic CD4 exocyclics inhibit binding of human immunodeficiency virus type 1 envelope to CD4 and virus replication in T lymphocytes. Nature Biotechnology. 15: 150-4. PMID 9035140 DOI: 10.1038/Nbt0297-150 |
0.336 |
|
| 1997 |
Kim JJ, Ayyavoo V, Bagarazzi ML, Chattergoon MA, Dang K, Wang B, Boyer JD, Weiner DB. In vivo engineering of a cellular immune response by coadministration of IL-12 expression vector with a DNA immunogen. Journal of Immunology (Baltimore, Md. : 1950). 158: 816-26. PMID 8992999 DOI: 10.1016/S0165-2478(97)85079-1 |
0.804 |
|
| 1997 |
Ugen KE, Srikantan V, Goedert JJ, Nelson RP, Williams WV, Weiner DB. Vertical transmission of human immunodeficiency virus type 1: seroreactivity by maternal antibodies to the carboxy region of the gp41 envelope glycoprotein. The Journal of Infectious Diseases. 175: 63-9. PMID 8985197 DOI: 10.1093/Infdis/175.1.63 |
0.326 |
|
| 1996 |
Boyer JD, Wang B, Ugen KE, Agadjanyan M, Javadian A, Frost P, Dang K, Carrano RA, Ciccarelli R, Coney L, Williams WV, Weiner DB. In vivo protective anti-HIV immune responses in non-human primates through DNA immunization. Journal of Medical Primatology. 25: 242-50. PMID 8892046 DOI: 10.1111/J.1600-0684.1996.Tb00022.X |
0.632 |
|
| 1996 |
Ayyavoo V, Ugen KE, Fernandes LS, Goedert JJ, Rubinstein A, Williams WV, Weiner DB. Analysis of genetic heterogeneity, antigenicity, and biological characteristics of HIV-1 in a maternal transmitter and nontransmitter patient pair. Dna and Cell Biology. 15: 571-80. PMID 8756338 DOI: 10.1089/Dna.1996.15.571 |
0.343 |
|
| 1996 |
Tokushige K, Wakita T, Pachuk C, Moradpour D, Weiner DB, Zurawski VR, Wands JR. Expression and immune response to hepatitis C virus core DNA-based vaccine constructs. Hepatology (Baltimore, Md.). 24: 14-20. PMID 8707253 DOI: 10.1002/Hep.510240104 |
0.396 |
|
| 1996 |
Cotropia J, Ugen KE, Kliks S, Broliden K, Broliden PA, Hoxie JA, Srikantan V, Williams WV, Weiner DB. A human monoclonal antibody to HIV-1 gp41 with neutralizing activity against diverse laboratory isolates. Journal of Acquired Immune Deficiency Syndromes and Human Retrovirology : Official Publication of the International Retrovirology Association. 12: 221-32. PMID 8673526 DOI: 10.1097/00042560-199607000-00002 |
0.351 |
|
| 1996 |
Li F, Bulbul R, Schumacher HR, Kieber-Emmons T, Callegari PE, Von Feldt JM, Norden D, Freundlich B, Wang B, Imonitie V, Chang CP, Nachamkin I, Weiner DB, Williams WV. Molecular detection of bacterial DNA in venereal-associated arthritis. Arthritis and Rheumatism. 39: 950-8. PMID 8651989 DOI: 10.1002/Art.1780390612 |
0.301 |
|
| 1995 |
Weiner DB. New vaccine strategies. Molecular Medicine Today. 1: 108-9. PMID 9415143 DOI: 10.1016/S1357-4310(95)80081-6 |
0.474 |
|
| 1995 |
Wang B, Boyer J, Srikantan V, Ugen K, Agadjanian M, Merva M, Gilbert L, Dang K, McCallus D, Moelling K, Carrano R, Williams WV, Coney L, Weiner DB. DNA inoculation induces cross clade anti-HIV-1 responses Annals of the New York Academy of Sciences. 772: 186-197. PMID 8546392 DOI: 10.1111/J.1749-6632.1995.Tb44744.X |
0.566 |
|
| 1995 |
Levy DN, Refaeli Y, Weiner DB. Extracellular Vpr protein increases cellular permissiveness to human immunodeficiency virus replication and reactivates virus from latency. Journal of Virology. 69: 1243-52. PMID 7815499 DOI: 10.1128/Jvi.69.2.1243-1252.1995 |
0.359 |
|
| 1995 |
Refaeli Y, Levy DN, Weiner DB. The glucocorticoid receptor type II complex is a target of the HIV-1 vpr gene product. Proceedings of the National Academy of Sciences of the United States of America. 92: 3621-5. PMID 7724608 DOI: 10.1073/Pnas.92.8.3621 |
0.316 |
|
| 1995 |
Levy DN, Refaeli Y, Weiner DB. The vpr regulatory gene of HIV. Current Topics in Microbiology and Immunology. 193: 209-36. PMID 7648876 DOI: 10.1007/978-3-642-78929-8_11 |
0.316 |
|
| 1995 |
Wang B, Boyer J, Srikantan V, Ugen K, Gilbert L, Phan C, Dang K, Merva M, Agadjanyan MG, Newman M, Carrano R, McCallus D, Coney L, Villiams WV, Weiner DB. Induction of humoral and cellular immune responses to the human immunodeficiency type 1 virus in nonhuman primates by in vivo DNA inoculation Virology. 211: 102-112. PMID 7645204 DOI: 10.1006/Viro.1995.1383 |
0.586 |
|
| 1995 |
Wang B, Merva M, Dang K, Ugen KE, Williams WV, Weiner DB. Immunization by direct DNA inoculation induces rejection of tumor cell challenge. Human Gene Therapy. 6: 407-18. PMID 7612698 DOI: 10.1089/Hum.1995.6.4-407 |
0.493 |
|
| 1994 |
Agadjanyan MG, Ugen KE, Wang B, Williams WV, Weiner DB. Identification of an 80-kilodalton membrane glycoprotein important for human T-cell leukemia virus type I and type II syncytium formation and infection Journal of Virology. 68: 485-493. PMID 8254759 DOI: 10.1128/Jvi.68.1.485-493.1994 |
0.307 |
|
| 1994 |
Athreya BA, Zulian F, Godillot AP, Weiner DB, Williams WV. Prolactin receptor levels on lymphocytes vary with menstrual cycle in women. Pathobiology : Journal of Immunopathology, Molecular and Cellular Biology. 62: 34-42. PMID 8031474 DOI: 10.1159/000163875 |
0.346 |
|
| 1994 |
Levy DN, Refaeli Y, MacGregor RR, Weiner DB. Serum Vpr regulates productive infection and latency of human immunodeficiency virus type 1. Proceedings of the National Academy of Sciences of the United States of America. 91: 10873-7. PMID 7971975 DOI: 10.1073/Pnas.91.23.10873 |
0.379 |
|
| 1994 |
Coney L, Wang B, Ugen KE, Boyer J, McCallus D, Srikantan V, Agadjanyan M, Pachuk CJ, Herold K, Merva M, Gilbert L, Deng K, Moelling K, Newman M, Williams WV, ... Weiner DB, et al. Facilitated DNA inoculation induces anti-HIV-1 immunity in vivo Vaccine. 12: 1545-1550. PMID 7879423 DOI: 10.1016/0264-410X(94)90082-5 |
0.621 |
|
| 1994 |
Srikantan V, Wang B, Satre MA, Ugen KE, Dang K, Scales F, Godillot AP, Williams WV, Weiner DB. Cloning and biological characterization of human single-chain Fv fragments that mediate neutralization of HIV-1 Aids. 8: 1525-1532. PMID 7848589 DOI: 10.1097/00002030-199411000-00002 |
0.364 |
|
| 1994 |
Kieber-Emmons T, Feldt JMV, Godillot AP, McCallus D, Srikantan V, Weiner DB, Williams WV. Isolated VH4 heavy chain variable regions bind DNA characterization of a recombinant antibody heavy chain library derived from patient(s) with active SLE. Lupus. 3: 379-392. PMID 7841991 DOI: 10.1177/096120339400300504 |
0.325 |
|
| 1994 |
Ugen KE, Von Feldt JM, Weiner DB, Ziegner UHM. Diagnosis and prediction of pediatric HIV-1 infection and AIDS: Current status Journal of Clinical Laboratory Analysis. 8: 309-314. PMID 7807285 DOI: 10.1002/Jcla.1860080509 |
0.327 |
|
| 1994 |
Ugen KE, Wang B, Ayyavoo V, Agadjanyan M, Boyer J, Li F, Kudchodkar S, Lin J, Merva M, Fernandes L, Williams WV, Weiner DB. DNA inoculation as a novel vaccination method against human retroviruses with rheumatic disease associations Immunologic Research. 13: 154-162. PMID 7775806 DOI: 10.1007/Bf02918276 |
0.568 |
|
| 1994 |
Williams WV, Fang Q, Feldt JMV, Boyer JD, Luchi M, Wang B, Weiner DB. Immunotherapeutic strategies targeting rheumatoid synovial T-cell receptors by DNA inoculation. Immunologic Research. 13: 145-153. PMID 7775805 DOI: 10.1007/Bf02918275 |
0.494 |
|
| 1994 |
Eaton AM, Ugen KE, Weiner DB, Wildes T, Levy JA. An anti-gp41 human monoclonal antibody that enhances HIV-1 infection in the absence of complement. Aids Research and Human Retroviruses. 10: 13-8. PMID 7514015 DOI: 10.1089/Aid.1994.10.13 |
0.351 |
|
| 1993 |
Wang B, Ugen KE, Srikantan V, Agadjanyan MG, Dang K, Refaeli Y, Sato AI, Boyer J, Williams WV, Weiner DB. Gene inoculation generates immune responses against human immunodeficiency virus type 1 Proceedings of the National Academy of Sciences of the United States of America. 90: 4156-4160. PMID 8483929 DOI: 10.1073/Pnas.90.9.4156 |
0.52 |
|
| 1993 |
Levy DN, Fernandes LS, Williams WV, Weiner DB. Induction of cell differentiation by human immunodeficiency virus 1 vpr. Cell. 72: 541-50. PMID 8440020 DOI: 10.1016/0092-8674(93)90073-Y |
0.34 |
|
| 1993 |
Williams WV, Boyer JD, Merva M, Livolsi V, Wilson D, Wang B, Weiner DB. Genetic infection induces protective in vivo immune responses. Dna and Cell Biology. 12: 675-83. PMID 8397826 DOI: 10.1089/Dna.1993.12.675 |
0.468 |
|
| 1993 |
Wang B, Agadjanyan MG, Srikantan V, Ugen KE, Hall W, Kaplan MH, Dang K, Williams WV, Weiner DB. Molecular cloning, expression, and biological characterization of an HTLV- II envelope glycoprotein: HIV-1 expression is permissive for HTLV-II-induced cell fusion Aids Research and Human Retroviruses. 9: 849-860. PMID 8257634 DOI: 10.1089/Aid.1993.9.849 |
0.339 |
|
| 1993 |
Wang B, Boyer J, Srikantan V, Coney L, Carrano R, Phan C, Merva M, Dang K, Agadjanan M, Gilbert L, Ugen KE, Williams WV, Weiner DB. DNA inoculation induces neutralizing immune responses against human immunodeficiency virus type 1 in mice and nonhuman primates Dna and Cell Biology. 12: 799-805. PMID 8216851 DOI: 10.1089/Dna.1993.12.799 |
0.551 |
|
| 1993 |
Athreya BH, Pletcher J, Zulian F, Weiner DB, Williams WV. Subset-specific effects of sex hormones and pituitary gonadotropins on human lymphocyte proliferation in vitro. Clinical Immunology and Immunopathology. 66: 201-11. PMID 8094329 DOI: 10.1006/Clin.1993.1026 |
0.336 |
|
| 1992 |
Williams WV, Weiner DB, Borofsky MA, Rubin DH, Yui K, Greene MI. Modulation of T cell responses with MHC-derived peptides. Immunologic Research. 11: 11-23. PMID 1602179 DOI: 10.1007/Bf02918604 |
0.324 |
|
| 1992 |
Williams WV, Sato A, Rossman M, Fang Q, Weiner DB. Specific DNA amplification utilizing the polymerase chain reaction and random oligonucleotide primers: application to the analysis of antigen receptor variable regions. Dna and Cell Biology. 11: 707-20. PMID 1418628 DOI: 10.1089/Dna.1992.11.707 |
0.312 |
|
| 1992 |
Weiner DB, Williams WV, Weisz PB, Greene MI. Synthetic cyclodextrin derivatives inhibit HIV infection in vitro Pathobiology. 60: 206-212. PMID 1388717 DOI: 10.1159/000163724 |
0.333 |
|
| 1992 |
Kieber-Emmons T, Krowka JF, Boyer J, Ugen KE, Williams WV, Morrow WJW, Weiner DB. Immunological characteristics of the putative CD4-binding site of the HIV-1 envelope protein Pathobiology. 60: 187-194. PMID 1388715 DOI: 10.1159/000163722 |
0.365 |
|
| 1992 |
Osther K, Wiik A, Black F, Skinhøj P, Kellermann G, Ugen KE, Williams WV, Weiner DB. PASSHIV-1 treatment of patients with HIV-1 infection. A preliminary report of a Phase I trial of hyperimmune porcine immunoglobulin to HIV-1 Aids. 6: 1457-1464. PMID 1362878 DOI: 10.1097/00002030-199212000-00006 |
0.353 |
|
| 1992 |
Chen S, Chrusciel RA, Nakanishi H, Raktabutr A, Johnson ME, Sato A, Weiner D, Hoxie J, Saragovi HU, Greene MI. Design and synthesis of a CD4 beta-turn mimetic that inhibits human immunodeficiency virus envelope glycoprotein gp120 binding and infection of human lymphocytes. Proceedings of the National Academy of Sciences of the United States of America. 89: 5872-6. PMID 1352879 DOI: 10.1073/Pnas.89.13.5872 |
0.306 |
|
| 1992 |
McCallus DE, Ugen KE, Sato AI, Williams WV, Weiner DB. Construction of a recombinant bacterial human CD4 expression system producing a bioactive CD4 molecule Viral Immunology. 5: 163-172. PMID 1319711 DOI: 10.1089/Vim.1992.5.163 |
0.336 |
|
| 1991 |
Weiner DB, Huebner K, Williams WV, Greene MI. Human genes other than CD4 facilitate HIV-1 infection of murine cells. Pathobiology : Journal of Immunopathology, Molecular and Cellular Biology. 59: 361-71. PMID 1930688 DOI: 10.1159/000163679 |
0.36 |
|
| 1991 |
Osther K, Kellermann G, Ugen KE, Williams WV, Weiner DB. Protective humoral immune responses to the human immunodeficiency virus induced in immunized pigs: A possible source of therapeutic immunoglobulin preparations Hybridoma. 10: 673-683. PMID 1816071 DOI: 10.1089/Hyb.1991.10.673 |
0.449 |
|
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