David M. Virshup - Related publications

Affiliations: 
University of Utah, Salt Lake City, UT 
Area:
Biochemistry, Molecular Physics, Molecular Biology
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50 most relevant papers in past 60 days:
Year Citation  Score
2020 Zhao L, Geng T, Sun K, Su S, Zhao Y, Bao N, Pan L, Sun H, Li M. Proteomic analysis reveals the molecular mechanism of Hippophae rhamnoides polysaccharide intervention in LPS-induced inflammation of IPEC-J2 cells in piglets. International Journal of Biological Macromolecules. PMID 32888998 DOI: 10.1016/j.ijbiomac.2020.08.235   
2020 Mitchell K, Mikwar M, Da Fonte D, Lu C, Tao B, Peng D, Udeesha Erandani WKC, Hu W, Trudeau VL. Secretoneurin is a secretogranin-2 derived hormonal peptide in vertebrate neuroendocrine systems. General and Comparative Endocrinology. 113588. PMID 32828813 DOI: 10.1016/j.ygcen.2020.113588   
2020 Shen C, Nayak A, Melendez RA, Wynn DT, Jackson J, Lee E, Ahmed Y, Robbins DJ. Casein Kinase 1α as a Regulator of Wnt-Driven Cancer. International Journal of Molecular Sciences. 21. PMID 32824859 DOI: 10.3390/ijms21165940   
2020 Wu PK, Becker A, Park JI. Growth Inhibitory Signaling of the Raf/MEK/ERK Pathway. International Journal of Molecular Sciences. 21. PMID 32751750 DOI: 10.3390/ijms21155436   
2020 Colella B, Colardo M, Iannone G, Contadini C, Saiz-Ladera C, Fuoco C, Barilà D, Velasco G, Segatto M, Di Bartolomeo S. mTOR Inhibition Leads to Src-Mediated EGFR Internalisation and Degradation in Glioma Cells. Cancers. 12. PMID 32823532 DOI: 10.3390/cancers12082266   
2020 Kumar S, Singh SK, Viswakarma N, Sondarva G, Nair RS, Sethupathi P, Dorman M, Sinha SC, Hoskins K, Thatcher G, Rana B, Rana A. Rationalized inhibition of mixed lineage kinase 3 and CD70 enhances life span and antitumor efficacy of CD8 T cells. Journal For Immunotherapy of Cancer. 8. PMID 32759234 DOI: 10.1136/jitc-2019-000494   
2020 Motta M, Pannone L, Pantaleoni F, Bocchinfuso G, Radio FC, Cecchetti S, Ciolfi A, Di Rocco M, Elting MW, Brilstra EH, Boni S, Mazzanti L, Tamburrino F, Walsh L, Payne K, et al. Enhanced MAPK1 Function Causes a Neurodevelopmental Disorder within the RASopathy Clinical Spectrum. American Journal of Human Genetics. PMID 32721402 DOI: 10.1016/j.ajhg.2020.06.018   
2020 Rothzerg E, Ingley E, Mullin B, Xue W, Wood D, Xu J. The Hippo in the room: Targeting the Hippo signalling pathway for osteosarcoma therapies. Journal of Cellular Physiology. PMID 32697358 DOI: 10.1002/jcp.29967   
2020 Marak BN, Dowarah J, Khiangte L, Singh VP. A comprehensive insight on the recent development of Cyclic Dependent Kinase inhibitors as anticancer agents. European Journal of Medicinal Chemistry. 203: 112571. PMID 32707525 DOI: 10.1016/j.ejmech.2020.112571   
2020 Hu B, Zhang Y, Deng T, Gu J, Liu J, Yang H, Xu Y, Yan Y, Yang F, Zhang H, Jin Y, Zhou J. PDPK1 regulates autophagosome biogenesis by binding to PIK3C3. Autophagy. PMID 32876514 DOI: 10.1080/15548627.2020.1817279   
2020 Melick CH, Jewell JL. Regulation of mTORC1 by Upstream Stimuli. Genes. 11. PMID 32854217 DOI: 10.3390/genes11090989   
2020 Shakeel I, Basheer N, Hasan GM, Afzal M, Hassan MI. Polo-like Kinase 1 as an emerging drug target: Structure, function and therapeutic implications. Journal of Drug Targeting. 1-43. PMID 32886539 DOI: 10.1080/1061186X.2020.1818760   
2020 Kang BW, Chau I. Molecular target: pan-AKT in gastric cancer. Esmo Open. 5. PMID 32948630 DOI: 10.1136/esmoopen-2020-000728   
2020 Fulcher LJ, Sapkota GP. Mitotic kinase anchoring proteins: the navigators of cell division. Cell Cycle (Georgetown, Tex.). 19: 505-524. PMID 32048898 DOI: 10.1080/15384101.2020.1728014   
2020 Afrose SS, Junaid M, Akter Y, Tania M, Zheng M, Khan MA. Targeting kinases with thymoquinone: a molecular approach to cancer therapeutics. Drug Discovery Today. PMID 32721537 DOI: 10.1016/j.drudis.2020.07.019   
2020 Jiao Y, Li J, Zhu S, Ahmed JZ, Li M, Shi D, Huang B. PI3K inhibitor reduces in vitro maturation and developmental competence of porcine oocytes. Theriogenology. 157: 432-439. PMID 32877843 DOI: 10.1016/j.theriogenology.2020.08.019   
2020 Lacey BM, Xu Z, Chai X, Laskey J, Fradera X, Mittal P, Mishra S, Piesvaux J, Saradjian P, Shaffer L, Vassileva G, Gerdt C, Wang Y, Ferguson H, Smith DM, et al. Development of High-Throughput Assays for Evaluation of Hematopoietic Progenitor Kinase 1 Inhibitors. Slas Discovery : Advancing Life Sciences R & D. 2472555220952071. PMID 32844715 DOI: 10.1177/2472555220952071   
2020 Buljan M, Ciuffa R, van Drogen A, Vichalkovski A, Mehnert M, Rosenberger G, Lee S, Varjosalo M, Pernas LE, Spegg V, Snijder B, Aebersold R, Gstaiger M. Kinase Interaction Network Expands Functional and Disease Roles of Human Kinases. Molecular Cell. PMID 32707033 DOI: 10.1016/j.molcel.2020.07.001   
2020 Ma H, Li G, Su Z. KSP: an integrated method for predicting catalyzing kinases of phosphorylation sites in proteins. Bmc Genomics. 21: 537. PMID 32753030 DOI: 10.1186/s12864-020-06895-2   
2020 Chan LN, Murakami MA, Robinson ME, Caeser R, Sadras T, Lee J, Cosgun KN, Kume K, Khairnar V, Xiao G, Ahmed MA, Aghania E, Deb G, Hurtz C, Shojaee S, et al. Signalling input from divergent pathways subverts B cell transformation. Nature. PMID 32699415 DOI: 10.1038/s41586-020-2513-4   
2020 Su Y, Wang X, Guo Z, Wang J. Aberrant JmjC domain-containing protein 8 (JMJD8) expression promotes activation of AKT and tumor epithelial-mesenchymal transition. Oncogene. PMID 32879443 DOI: 10.1038/s41388-020-01446-1   
2020 Rödiger A, Galonska J, Bergner E, Agne B, Helm S, Alseekh S, Fernie AR, Thieme D, Hoehenwarter W, Hause G, Pfannschmidt T, Baginsky S. Working day and night: plastid casein kinase 2 catalyses phosphorylation of proteins with diverse functions in light- and dark-adapted plastids. The Plant Journal : For Cell and Molecular Biology. PMID 32745315 DOI: 10.1111/tpj.14944   
2020 Hoy JJ, Salinas Parra N, Park J, Kuhn S, Iglesias-Bartolome R. Protein kinase A inhibitor proteins (PKIs) divert GPCR-Gαs-cAMP signaling toward EPAC and ERK activation and are involved in tumor growth. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 32830375 DOI: 10.1096/fj.202001515R   
2020 Zaoui K, Smith HW, Park M, Duhamel S. ARF6 controls RHOB targeting to endosomes regulating cancer cell invasion. Molecular & Cellular Oncology. 7: 1766932. PMID 32944628 DOI: 10.1080/23723556.2020.1766932   
2020 Cuny GD, Degterev A. RIPK protein kinase family: Atypical lives of typical kinases. Seminars in Cell & Developmental Biology. PMID 32732131 DOI: 10.1016/j.semcdb.2020.06.014   
2020 Sukumaran A, Choi K, Dasgupta B. Insight on Transcriptional Regulation of the Energy Sensing AMPK and Biosynthetic mTOR Pathway Genes. Frontiers in Cell and Developmental Biology. 8: 671. PMID 32903688 DOI: 10.3389/fcell.2020.00671   
2020 Truong AD, Hong Y, Nguyen HT, Nguyen CT, Chu NT, Tran HTT, Dang HV, Lillehoj HS, Hong YH. Molecular identification and characterization of a novel chicken leukocyte immunoglobulin-like receptor A5. British Poultry Science. PMID 32812773 DOI: 10.1080/00071668.2020.1812524   
2020 Truong AD, Hong Y, Nguyen HT, Nguyen CT, Chu NT, Tran HTT, Dang HV, Lillehoj HS, Hong YH. Molecular identification and characterization of a novel chicken leukocyte immunoglobulin-like receptor A5. British Poultry Science. PMID 32812773 DOI: 10.1080/00071668.2020.1812524   
2020 He P, Mann-Collura O, Fling J, Edara N, Hetz R, Razzaque MS. High phosphate actively induces cytotoxicity by rewiring pro-survival and pro-apoptotic signaling networks in HEK293 and HeLa cells. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 32892444 DOI: 10.1096/fj.202000799RR   
2020 Marshall CB, KleinJan F, Gebregiworgis T, Lee KY, Fang Z, Eves BJ, Liu NF, Gasmi-Seabrook GMC, Enomoto M, Ikura M. NMR in integrated biophysical drug discovery for RAS: past, present, and future. Journal of Biomolecular Nmr. PMID 32804298 DOI: 10.1007/s10858-020-00338-6   
2020 Ayati M, Chance MR, Koyuturk M. Co-Phosphorylation Networks Reveal Subtype-Specific Signaling Modules in Breast Cancer. Bioinformatics (Oxford, England). PMID 32730576 DOI: 10.1093/bioinformatics/btaa678   
2020 More KR, Kaur I, Giai Gianetto Q, Invergo BM, Chaze T, Jain R, Huon C, Gutenbrunner P, Weisser H, Matondo M, Choudhary JS, Langsley G, Singh S, Chitnis CE. Phosphorylation-Dependent Assembly of a 14-3-3 Mediated Signaling Complex during Red Blood Cell Invasion by Plasmodium falciparum Merozoites. Mbio. 11. PMID 32817103 DOI: 10.1128/mBio.01287-20   
2020 de Assis LJ, Silva LP, Liu L, Schmitt K, Valerius O, Braus GH, Ries LNA, Goldman GH. The High Osmolarity Glycerol Mitogen-Activated Protein Kinase regulates glucose catabolite repression in filamentous fungi. Plos Genetics. 16: e1008996. PMID 32841242 DOI: 10.1371/journal.pgen.1008996   
2020 Schönholzer MT, Migliavacca J, Alvarez E, Santhana Kumar K, Neve A, Gries A, Ma M, Grotzer MA, Baumgartner M. Real-time sensing of MAPK signaling in medulloblastoma cells reveals cellular evasion mechanism counteracting dasatinib blockade of ERK activation during invasion. Neoplasia (New York, N.Y.). 22: 470-483. PMID 32818841 DOI: 10.1016/j.neo.2020.07.006   
2020 Yang HW, Jung Y, Kim HD, Kim J. Ribosomal protein S3-derived repair domain peptides regulate UV-induced matrix metalloproteinase-1. Biochemical and Biophysical Research Communications. 530: 149-154. PMID 32828277 DOI: 10.1016/j.bbrc.2020.06.094   
2020 CB Hanna, D Mudaliar, K John, CL Allen, L Sun, JE Hawkinson, Schönbrunn E, Georg GI, Jensen JT. Development of WEE2 kinase inhibitors as novel non-hormonal female contraceptives that target meiosis Biology of Reproduction. 103. PMID 32667031 DOI: 10.1093/biolre/ioaa097   
2020 Hanna CB, Mudaliar D, John K, Allen CL, Sun L, Hawkinson JE, Schönbrunn E, Georg GI, Jensen JT. Development of WEE2 kinase inhibitors as novel non-hormonal female contraceptives that target meiosis Biology of Reproduction. 103. PMID 32667031 DOI: 10.1093/biolre/ioaa097   
2020 Zeng C, Xiong D, Zhang K, Yao J. Shank-associated RH domain interactor signaling in tumorigenesis. Oncology Letters. 20: 2579-2586. PMID 32782575 DOI: 10.3892/ol.2020.11850   
2020 Adam K, Ning J, Reina J, Hunter T. NME/NM23/NDPK and Histidine Phosphorylation. International Journal of Molecular Sciences. 21. PMID 32823988 DOI: 10.3390/ijms21165848   
2020 Liao H, Cai J, Liu C, Shen L, Pu X, Yao Y, Han B, Yu T, Cheng SY, Yue S. Protein phosphatase 4 promotes Hedgehog signaling through dephosphorylation of Suppressor of fused. Cell Death & Disease. 11: 686. PMID 32826873 DOI: 10.1038/s41419-020-02843-w   
2020 Kim MS, Jin W. TrkB Inhibits the BMP Signaling-Mediated Growth Inhibition of Cancer Cells. Cancers. 12. PMID 32731498 DOI: 10.3390/cancers12082095   
2020 Kim MS, Jin W. TrkB Inhibits the BMP Signaling-Mediated Growth Inhibition of Cancer Cells. Cancers. 12. PMID 32731498 DOI: 10.3390/cancers12082095   
2020 Luo F, Jiang N, Wang H, Shao X, Chen R, Bai R, Wang Y. [Phosphoproteomic analysis of peripheral blood mononuclear cells of ankylosing spondylitis patients]. Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi = Chinese Journal of Cellular and Molecular Immunology. 36: 444-450. PMID 32696757   
2020 Xu X, Lemmens LJM, den Hamer A, Merkx M, Ottmann C, Brunsveld L. Modular bioengineered kinase sensors scaffold protein-mediated split-luciferase complementation. Chemical Science. 11: 5532-5536. PMID 32874496 DOI: 10.1039/d0sc00074d   
2020 Lee GH, Kim YS, Kwon E, Yun JW, Kang BC. Toxicologic Evaluation for Amorphous Silica Nanoparticles: Genotoxic and Non-Genotoxic Tumor-Promoting Potential. Pharmaceutics. 12. PMID 32872498 DOI: 10.3390/pharmaceutics12090826   
2020 Spengler K, Zibrova D, Woods A, Langendorf CG, Scott JW, Carling D, Heller R. Protein kinase A negatively regulates VEGF-induced AMPK activation by phosphorylating CaMKK2 at serine 495. The Biochemical Journal. PMID 32869834 DOI: 10.1042/BCJ20200555   
2020 Gu Y, Wang T, Chen J, Zhou Z, Wang Y, Chen J, Liu N, Jiang Z. The Chinese Herb Isolate Isorhapontigenin protects against oxidative stress injury by inhibiting the activation of PI3K/Akt signaling pathway. Journal of Integrative Neuroscience. 19: 333-340. PMID 32706197 DOI: 10.31083/j.jin.2020.02.1152   
2020 Liu S, Yin P, Dotts AJ, Kujawa SA, Coon V JS, Wei JJ, Chakravarti D, Bulun SE. Activation of protein kinase B by WNT4 as a regulator of uterine leiomyoma stem cell function. Fertility and Sterility. PMID 32892998 DOI: 10.1016/j.fertnstert.2020.06.045   
2020 Bautista L, Knippler CM, Ringel MD. p21-Activated Kinases in Thyroid Cancer. Endocrinology. 161. PMID 32609833 DOI: 10.1210/endocr/bqaa105   
2020 Wolfstetter G, Pfeifer K, Backman M, Masudi TA, Mendoza-García P, Chen S, Sonnenberg H, Sukumar SK, Uçkun E, Varshney GK, Uv A, Palmer RH. Identification of the Wallenda JNKKK as an Alk suppressor reveals increased competitiveness of Alk-expressing cells. Scientific Reports. 10: 14954. PMID 32917927 DOI: 10.1038/s41598-020-70890-6