Year |
Citation |
Score |
2012 |
Wang Y, Guan S, Acharya P, Liu Y, Thirumaran RK, Brandman R, Schuetz EG, Burlingame AL, Correia MA. Multisite phosphorylation of human liver cytochrome P450 3A4 enhances Its gp78- and CHIP-mediated ubiquitination: a pivotal role of its Ser-478 residue in the gp78-catalyzed reaction. Molecular & Cellular Proteomics : McP. 11: M111.010132. PMID 22101235 DOI: 10.1074/Mcp.M111.010132 |
0.428 |
|
2011 |
Agnani D, Acharya P, Martinez E, Tran TT, Abraham F, Tobin F, Ellens H, Bentz J. Fitting the elementary rate constants of the P-gp transporter network in the hMDR1-MDCK confluent cell monolayer using a particle swarm algorithm. Plos One. 6: e25086. PMID 22028772 DOI: 10.1371/Journal.Pone.0025086 |
0.646 |
|
2011 |
Wang Y, Guan S, Acharya P, Koop DR, Liu Y, Liao M, Burlingame AL, Correia MA. Ubiquitin-dependent proteasomal degradation of human liver cytochrome P450 2E1: identification of sites targeted for phosphorylation and ubiquitination. The Journal of Biological Chemistry. 286: 9443-56. PMID 21209460 DOI: 10.1074/Jbc.M110.176685 |
0.356 |
|
2011 |
Acharya P, Liao M, Engel JC, Correia MA. Liver cytochrome P450 3A endoplasmic reticulum-associated degradation: a major role for the p97 AAA ATPase in cytochrome P450 3A extraction into the cytosol. The Journal of Biological Chemistry. 286: 3815-28. PMID 21107009 DOI: 10.1074/Jbc.M110.186981 |
0.438 |
|
2010 |
Kim SM, Acharya P, Engel JC, Correia MA. Liver cytochrome P450 3A ubiquitination in vivo by gp78/autocrine motility factor receptor and C terminus of Hsp70-interacting protein (CHIP) E3 ubiquitin ligases: physiological and pharmacological relevance. The Journal of Biological Chemistry. 285: 35866-77. PMID 20819951 DOI: 10.1074/Jbc.M110.167189 |
0.407 |
|
2010 |
Lumen AA, Acharya P, Polli JW, Ayrton A, Ellens H, Bentz J. If the KI is defined by the free energy of binding to P-glycoprotein, which kinetic parameters define the IC50 for the Madin-Darby canine kidney II cell line overexpressing human multidrug resistance 1 confluent cell monolayer? Drug Metabolism and Disposition: the Biological Fate of Chemicals. 38: 260-9. PMID 19889884 DOI: 10.1124/Dmd.109.029843 |
0.545 |
|
2009 |
Wang Y, Liao M, Hoe N, Acharya P, Deng C, Krutchinsky AN, Correia MA. A role for protein phosphorylation in cytochrome P450 3A4 ubiquitin-dependent proteasomal degradation. The Journal of Biological Chemistry. 284: 5671-84. PMID 19095658 DOI: 10.1074/Jbc.M806104200 |
0.338 |
|
2008 |
Acharya P, O'Connor MP, Polli JW, Ayrton A, Ellens H, Bentz J. Kinetic identification of membrane transporters that assist P-glycoprotein-mediated transport of digoxin and loperamide through a confluent monolayer of MDCKII-hMDR1 cells. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 36: 452-60. PMID 17967933 DOI: 10.1124/Dmd.107.017301 |
0.634 |
|
2006 |
Acharya P, Tran TT, Polli JW, Ayrton A, Ellens H, Bentz J. P-Glycoprotein (P-gp) expressed in a confluent monolayer of hMDR1-MDCKII cells has more than one efflux pathway with cooperative binding sites. Biochemistry. 45: 15505-19. PMID 17176072 DOI: 10.1021/Bi060593B |
0.636 |
|
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