Year |
Citation |
Score |
2020 |
Jones E, Hummel SL, Cameron DM, Beard DA, Carlson BE. Two Distinct Classes of Heart Failure with Preserved Ejection Fraction Emerge from Analysis of Standard Clinical Measures using Mechanistic Models of the Cardiovascular System The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.06305 |
0.309 |
|
2020 |
Lopez R, Gao X, Marzban B, Lauinger E, Bergh FVd, Beard DA. Impaired Myocardial Energetics Contributes to Mechanical Dysfunction in Decompensated Failing Hearts Biophysical Journal. 118. DOI: 10.1016/J.Bpj.2019.11.2526 |
0.304 |
|
2019 |
Gao X, Jakovljevic DG, Beard DA. Cardiac Metabolic Limitations Contribute to Diminished Performance of the Heart in Aging. Biophysical Journal. PMID 31395314 DOI: 10.1016/J.Bpj.2019.06.026 |
0.348 |
|
2019 |
Jones E, Cameron DM, Beard DA, Hummel SL, Carlson BE. Cardiovascular System Model-Based Phenotyping of Heart Failure with Preserved Ejection Fraction Journal of Cardiac Failure. 25. DOI: 10.1016/J.Cardfail.2019.07.092 |
0.381 |
|
2018 |
Beard DA. Assessing the Validity and Utility of the Guyton Model of Arterial Blood Pressure Control. Hypertension (Dallas, Tex. : 1979). 72: 1272-1273. PMID 30571241 DOI: 10.1161/Hypertensionaha.118.11998 |
0.322 |
|
2018 |
Kelly RA, Leedale J, Harrell A, Beard DA, Randle LE, Chadwick AE, Webb SD. Modelling the impact of changes in the extracellular environment on the cytosolic free NAD+/NADH ratio during cell culture. Plos One. 13: e0207803. PMID 30496306 DOI: 10.1371/Journal.Pone.0207803 |
0.344 |
|
2018 |
Kosinski SA, Carlson BE, Hummel SL, Brook RD, Beard DA. Computational Model-Based Assessment of Baroreflex Function from Response to Valsalva Maneuver. Journal of Applied Physiology (Bethesda, Md. : 1985). PMID 30236047 DOI: 10.1152/Japplphysiol.00095.2018 |
0.36 |
|
2018 |
Pewowaruk RJ, Philip JL, Tewari SG, Chen CS, Nyaeme MS, Wang Z, Tabima DM, Baker AJ, Beard DA, Chesler NC. Multiscale Computational Analysis of Right Ventricular Mechanoenergetics. Journal of Biomechanical Engineering. 140. PMID 30003251 DOI: 10.1115/1.4040044 |
0.703 |
|
2018 |
Philip JL, Pewowaruk RJ, Chen CS, Tabima DM, Beard DA, Baker AJ, Chesler NC. Impaired Myofilament Contraction Drives Right Ventricular Failure Secondary to Pressure Overload: Model Simulations, Experimental Validation, and Treatment Predictions. Frontiers in Physiology. 9: 731. PMID 29997518 DOI: 10.3389/Fphys.2018.00731 |
0.392 |
|
2018 |
Moxley MA, Vinnakota KC, Bazil JN, Qi NR, Beard DA. Systems-level computational modeling demonstrates fuel selection switching in high capacity running and low capacity running rats. Plos Computational Biology. 14: e1005982. PMID 29474500 DOI: 10.1371/Journal.Pcbi.1005982 |
0.318 |
|
2018 |
Lopez R, Gao X, Van den Bergh F, Dasika S, Beard D. Quantifying the Contribution of Cardiomyocyte Metabolic Dysfunction to the Heart Mechanical Function Biophysical Journal. 114: 499a. DOI: 10.1016/J.Bpj.2017.11.2730 |
0.316 |
|
2017 |
Bakermans AJ, Bazil JN, Nederveen AJ, Strijkers GJ, Boekholdt SM, Beard DA, Jeneson JAL. Human Cardiac 31P-MR Spectroscopy at 3 Tesla Cannot Detect Failing Myocardial Energy Homeostasis during Exercise. Frontiers in Physiology. 8: 939. PMID 29230178 DOI: 10.3389/Fphys.2017.00939 |
0.314 |
|
2017 |
Thiagarajan R, Alavi A, Podichetty JT, Bazil JN, Beard DA. The feasibility of genome-scale biological network inference using Graphics Processing Units. Algorithms For Molecular Biology : Amb. 12: 8. PMID 28344638 DOI: 10.1186/S13015-017-0100-5 |
0.301 |
|
2017 |
Liu A, Philip J, Vinnakota KC, Van den Bergh F, Tabima DM, Hacker T, Beard DA, Chesler NC. Estrogen maintains mitochondrial content and function in the right ventricle of rats with pulmonary hypertension. Physiological Reports. 5. PMID 28320896 DOI: 10.14814/Phy2.13157 |
0.303 |
|
2017 |
Dasika SK, Kandel SM, Beard DA. Regulation of Carbon Substrate Utilization by Cardiac Mitochondria Biophysical Journal. 112: 131a. DOI: 10.1016/J.Bpj.2016.11.727 |
0.342 |
|
2016 |
Tewari SG, Bugenhagen SM, Vinnakota KC, Rice JJ, Janssen PM, Beard DA. Influence of metabolic dysfunction on cardiac mechanics in decompensated hypertrophy and heart failure. Journal of Molecular and Cellular Cardiology. PMID 27085901 DOI: 10.1016/J.Yjmcc.2016.04.003 |
0.774 |
|
2016 |
Vinnakota KC, Cha CY, Rorsman P, Balaban RS, La Gerche A, Wade-Martins R, Beard DA, Jeneson JA. Improving the physiological realism of experimental models. Interface Focus. 6: 20150076. PMID 27051507 DOI: 10.1098/Rsfs.2015.0076 |
0.343 |
|
2016 |
Pradhan RK, Feigl EO, Gorman MW, Brengelmann GL, Beard DA. Open-Loop (Feed-Forward) and Feedback Control of Coronary Blood Flow during Exercise Cardiac Pacing and Pressure Changes. American Journal of Physiology. Heart and Circulatory Physiology. ajpheart.00663.2015. PMID 27037372 DOI: 10.1152/Ajpheart.00663.2015 |
0.595 |
|
2016 |
Vinnakota KC, Bazil JN, Van den Bergh F, Wiseman RW, Beard DA. Feedback Regulation and Time Hierarchy of Oxidative Phosphorylation in Cardiac Mitochondria. Biophysical Journal. 110: 972-80. PMID 26910434 DOI: 10.1016/J.Bpj.2016.01.003 |
0.317 |
|
2016 |
Bazil JN, Beard DA, Vinnakota KC. Catalytic Coupling of Oxidative Phosphorylation, ATP Demand, and Reactive Oxygen Species Generation. Biophysical Journal. 110: 962-71. PMID 26910433 DOI: 10.1016/J.Bpj.2015.09.036 |
0.383 |
|
2016 |
Vinnakota KC, Singhal A, Van den Bergh F, Bagher-Oskouei M, Wiseman RW, Beard DA. Open-Loop Control of Oxidative Phosphorylation in Skeletal and Cardiac Muscle Mitochondria by Ca(2.). Biophysical Journal. 110: 954-61. PMID 26910432 DOI: 10.1016/J.Bpj.2015.12.018 |
0.302 |
|
2016 |
Lee P, Carlson BE, Chesler N, Olufsen MS, Qureshi MU, Smith NP, Sochi T, Beard DA. Heterogeneous mechanics of the mouse pulmonary arterial network. Biomechanics and Modeling in Mechanobiology. PMID 26792789 DOI: 10.1007/S10237-015-0757-Y |
0.357 |
|
2016 |
Bassingthwaighte JB, Raymond GM, Dash RK, Beard DA, Nolan M. The Pathway for Oxygen: Tutorial Modelling on Oxygen Transport from Air to Mitochondrion : The Pathway for Oxygen. Advances in Experimental Medicine and Biology. 876: 103-10. PMID 26782201 DOI: 10.1007/978-1-4939-3023-4_13 |
0.535 |
|
2015 |
Moxley MA, Beard DA, Bazil JN. Global Kinetic Analysis of Mammalian E3 Reveals pH-dependent NAD+/NADH Regulation, Physiological Kinetic Reversibility, and Catalytic Optimum. The Journal of Biological Chemistry. PMID 26644471 DOI: 10.1074/Jbc.M115.676619 |
0.332 |
|
2015 |
Bugenhagen SM, Beard DA. Computational analysis of the regulation of Ca(2+) dynamics in rat ventricular myocytes. Physical Biology. 12: 056008. PMID 26358004 DOI: 10.1088/1478-3975/12/5/056008 |
0.76 |
|
2015 |
Pannala VR, Beard DA, Dash RK. Letter to the Editor: Mitochondrial cytochrome c oxidase: mechanism of action and role in regulating oxidative phosphorylation. Journal of Applied Physiology (Bethesda, Md. : 1985). 119: 157. PMID 26177971 DOI: 10.1152/Japplphysiol.00290.2015 |
0.315 |
|
2015 |
Tewari SG, Bugenhagen SM, Palmer BM, Beard DA. Dynamics of cross-bridge cycling, ATP hydrolysis, force generation, and deformation in cardiac muscle. Journal of Molecular and Cellular Cardiology. PMID 25681584 DOI: 10.1016/J.Yjmcc.2015.02.006 |
0.773 |
|
2015 |
Dasika SK, Vinnakota KC, Beard DA. Characterization of the kinetics of cardiac cytosolic malate dehydrogenase and comparative analysis of cytosolic and mitochondrial isoforms. Biophysical Journal. 108: 420-30. PMID 25606689 DOI: 10.1016/J.Bpj.2014.11.3466 |
0.328 |
|
2015 |
Dasika SK, Vinnakota KC, Beard DA. Determination of the catalytic mechanism for mitochondrial malate dehydrogenase. Biophysical Journal. 108: 408-19. PMID 25606688 DOI: 10.1016/J.Bpj.2014.11.3467 |
0.306 |
|
2015 |
Tewari S, Bugenhagen S, Palmer B, Beard D. Computational Model of Cross-Bridge Cycling and Force Generation to Explain the Effect of Metabolites on Cardiac Muscle Mechanics Biophysical Journal. 108: 444a. DOI: 10.1016/J.Bpj.2014.11.2425 |
0.775 |
|
2015 |
Beard DA. The Emergence of Heart Failure as a Consequence of Myocardial Metabolic Dysfunction Biophysical Journal. 108: 33a. DOI: 10.1016/J.Bpj.2014.11.207 |
0.361 |
|
2014 |
Tewari SG, Zhou Y, Otto BJ, Dash RK, Kwok WM, Beard DA. Markov chain Monte Carlo based analysis of post-translationally modified VDAC gating kinetics. Frontiers in Physiology. 5: 513. PMID 25628567 DOI: 10.3389/Fphys.2014.00513 |
0.718 |
|
2014 |
Moxley MA, Beard DA, Bazil JN. A pH-dependent kinetic model of dihydrolipoamide dehydrogenase from multiple organisms. Biophysical Journal. 107: 2993-3007. PMID 25517164 DOI: 10.1016/J.Bpj.2014.09.025 |
0.329 |
|
2014 |
Pettersen KH, Bugenhagen SM, Nauman J, Beard DA, Omholt SW. Arterial stiffening provides sufficient explanation for primary hypertension. Plos Computational Biology. 10: e1003634. PMID 24853828 DOI: 10.1371/Journal.Pcbi.1003634 |
0.768 |
|
2013 |
Beard DA, Pettersen KH, Carlson BE, Omholt SW, Bugenhagen SM. A computational analysis of the long-term regulation of arterial pressure. F1000research. 2: 208. PMID 24555102 DOI: 10.12688/F1000Research.2-208.V2 |
0.771 |
|
2013 |
Tewari SG, Bugenhagen SM, Wang Z, Schreier DA, Carlson BE, Chesler NC, Beard DA. Analysis of cardiovascular dynamics in pulmonary hypertensive C57BL6/J mice. Frontiers in Physiology. 4: 355. PMID 24376421 DOI: 10.3389/Fphys.2013.00355 |
0.757 |
|
2013 |
Beard DA, Feigl EO. Rebuttal from Daniel Beard and Eric Feigl. The Journal of Physiology. 591: 5801. PMID 24293528 DOI: 10.1113/Jphysiol.2013.264663 |
0.584 |
|
2013 |
Beard DA, Feigl EO. CrossTalk opposing view: Guyton's venous return curves should not be taught. The Journal of Physiology. 591: 5795-7. PMID 24293526 DOI: 10.1113/Jphysiol.2013.260034 |
0.536 |
|
2013 |
Bazil JN, Vinnakota KC, Wu F, Beard DA. Analysis of the kinetics and bistability of ubiquinol:cytochrome c oxidoreductase. Biophysical Journal. 105: 343-55. PMID 23870256 DOI: 10.1016/J.Bpj.2013.05.033 |
0.335 |
|
2013 |
Beard DA, Feigl EO. Reply to "letter to the editor: a return to the venous return controversy: a visual aid for combatants'". American Journal of Physiology. Heart and Circulatory Physiology. 304: H489. PMID 23377151 DOI: 10.1152/Ajpheart.00886.2012 |
0.625 |
|
2013 |
Li X, Wu F, Beard DA. Identification of the kinetic mechanism of succinyl-CoA synthetase. Bioscience Reports. 33: 145-63. PMID 23088689 DOI: 10.1042/Bsr20120069 |
0.338 |
|
2013 |
Sanders MD, Tewari S, Kurth T, Ryan RP, Cowley AW, Beard DA, Carlson BE. Measurement of cardiac function using dual catheterization in the Dahl SS rat on low salt The Faseb Journal. 27. DOI: 10.6084/M9.Figshare.723381.V1 |
0.641 |
|
2013 |
Bazil J, Vinnakota KC, Fan W, Beard DA. A Minimal Model of Ubiquinol:Cytochrome C Reductase Capable of Simulating Superoxide Production Biophysical Journal. 104: 304a. DOI: 10.1016/J.Bpj.2012.11.1693 |
0.336 |
|
2012 |
Bugenhagen SM, Beard DA. Specification, construction, and exact reduction of state transition system models of biochemical processes. The Journal of Chemical Physics. 137: 154108. PMID 23083149 DOI: 10.1063/1.4758074 |
0.77 |
|
2012 |
Tewari SG, Dash RK, Beard DA, Bazil JN. A biophysical model of the mitochondrial ATP-Mg/P(i) carrier. Biophysical Journal. 103: 1616-25. PMID 23062354 DOI: 10.1016/J.Bpj.2012.08.050 |
0.667 |
|
2012 |
Bassingthwaighte JB, Beard DA, Carlson BE, Dash RK, Vinnakota K. Modeling to link regional myocardial work, metabolism and blood flows. Annals of Biomedical Engineering. 40: 2379-98. PMID 22915334 DOI: 10.1007/S10439-012-0613-5 |
0.578 |
|
2012 |
Beard DA, Neal ML, Tabesh-Saleki N, Thompson CT, Bassingthwaighte JB, Shimoyama M, Carlson BE. Multiscale modeling and data integration in the virtual physiological rat project. Annals of Biomedical Engineering. 40: 2365-78. PMID 22805979 DOI: 10.1007/S10439-012-0611-7 |
0.566 |
|
2012 |
Thompson MD, Beard DA, Wu F. Use of partition coefficients in flow-limited physiologically-based pharmacokinetic modeling. Journal of Pharmacokinetics and Pharmacodynamics. 39: 313-27. PMID 22639356 DOI: 10.1007/S10928-012-9252-6 |
0.343 |
|
2012 |
Beard DA, Mescam M. Mechanisms of pressure-diuresis and pressure-natriuresis in Dahl salt-resistant and Dahl salt-sensitive rats. Bmc Physiology. 12: 6. PMID 22583378 DOI: 10.1186/1472-6793-12-6 |
0.343 |
|
2012 |
Bugenhagen SM, Beard DA. Specification, Construction, and Exact Reduction of Finite State Transition System Models of Biochemical Processes Biophysical Journal. 102: 5-6. DOI: 10.1016/J.Bpj.2011.11.3245 |
0.761 |
|
2012 |
Vinnakota KC, Wu F, Beard DA. A Quantitative Description of Oxidative Phosphorylation in Cardiac Mitochondria Biophysical Journal. 102: 572a. DOI: 10.1016/J.Bpj.2011.11.3114 |
0.34 |
|
2012 |
Beard DA, Neal ML, Tabesh-Saleki N, Thompson CT, Bassingthwaighte JB, Shimoyama M, Carlson BE. Erratum to: Multiscale Modeling and Data Integration in the Virtual Physiological Rat Project Annals of Biomedical Engineering. 40: 2501-2501. DOI: 10.1007/S10439-012-0641-1 |
0.467 |
|
2011 |
Pradhan RK, Qi F, Beard DA, Dash RK. Characterization of Mg2+ inhibition of mitochondrial Ca2+ uptake by a mechanistic model of mitochondrial Ca2+ uniporter. Biophysical Journal. 101: 2071-81. PMID 22067144 DOI: 10.1016/J.Bpj.2011.09.029 |
0.306 |
|
2011 |
Qi F, Pradhan RK, Dash RK, Beard DA. Detailed kinetics and regulation of mammalian 2-oxoglutarate dehydrogenase. Bmc Biochemistry. 12: 53. PMID 21943256 DOI: 10.1186/1471-2091-12-53 |
0.35 |
|
2011 |
Wu F, Beard DA, Frisbee JC. Computational analyses of intravascular tracer washout reveal altered capillary-level flow distributions in obese Zucker rats. The Journal of Physiology. 589: 4527-43. PMID 21788350 DOI: 10.1113/Jphysiol.2011.209775 |
0.311 |
|
2011 |
Vinnakota KC, Dash RK, Beard DA. Stimulatory effects of calcium on respiration and NAD(P)H synthesis in intact rat heart mitochondria utilizing physiological substrates cannot explain respiratory control in vivo. The Journal of Biological Chemistry. 286: 30816-22. PMID 21757763 DOI: 10.1074/Jbc.M111.242529 |
0.314 |
|
2011 |
Beard DA, Feigl EO. Understanding Guyton's venous return curves. American Journal of Physiology. Heart and Circulatory Physiology. 301: H629-33. PMID 21666119 DOI: 10.1152/Ajpheart.00228.2011 |
0.616 |
|
2011 |
Thompson MD, Beard DA. Development of appropriate equations for physiologically based pharmacokinetic modeling of permeability-limited and flow-limited transport. Journal of Pharmacokinetics and Pharmacodynamics. 38: 405-21. PMID 21584718 DOI: 10.1007/S10928-011-9200-X |
0.35 |
|
2011 |
Carlson BE, Beard DA. Mechanical control of cation channels in the myogenic response. American Journal of Physiology. Heart and Circulatory Physiology. 301: H331-43. PMID 21572020 DOI: 10.1152/Ajpheart.00131.2011 |
0.323 |
|
2011 |
Waltemath D, Adams R, Beard DA, Bergmann FT, Bhalla US, Britten R, Chelliah V, Cooling MT, Cooper J, Crampin EJ, Garny A, Hoops S, Hucka M, Hunter P, Klipp E, et al. Minimum Information About a Simulation Experiment (MIASE). Plos Computational Biology. 7: e1001122. PMID 21552546 DOI: 10.1371/Journal.Pcbi.1001122 |
0.302 |
|
2011 |
Mescam M, Vinnakota KC, Beard DA. Identification of the catalytic mechanism and estimation of kinetic parameters for fumarase. The Journal of Biological Chemistry. 286: 21100-9. PMID 21498518 DOI: 10.1074/Jbc.M110.214452 |
0.341 |
|
2011 |
Vinnakota KC, Beard DA. Kinetic analysis and design of experiments to identify the catalytic mechanism of the monocarboxylate transporter isoforms 4 and 1. Biophysical Journal. 100: 369-80. PMID 21244833 DOI: 10.1016/J.Bpj.2010.11.079 |
0.324 |
|
2011 |
Beard DA. Simulation of cellular biochemical system kinetics. Wiley Interdisciplinary Reviews. Systems Biology and Medicine. 3: 136-46. PMID 21171044 DOI: 10.1002/Wsbm.116 |
0.333 |
|
2011 |
Waters SL, Alastruey J, Beard DA, Bovendeerd PH, Davies PF, Jayaraman G, Jensen OE, Lee J, Parker KH, Popel AS, Secomb TW, Siebes M, Sherwin SJ, Shipley RJ, Smith NP, et al. Theoretical models for coronary vascular biomechanics: progress & challenges. Progress in Biophysics and Molecular Biology. 104: 49-76. PMID 21040741 DOI: 10.1016/J.Pbiomolbio.2010.10.001 |
0.365 |
|
2011 |
Fink M, Niederer SA, Cherry EM, Fenton FH, Koivumäki JT, Seemann G, Thul R, Zhang H, Sachse FB, Beard D, Crampin EJ, Smith NP. Cardiac cell modelling: observations from the heart of the cardiac physiome project. Progress in Biophysics and Molecular Biology. 104: 2-21. PMID 20303361 DOI: 10.1016/J.Pbiomolbio.2010.03.002 |
0.381 |
|
2010 |
Chen X, Qi F, Dash RK, Beard DA. Kinetics and regulation of mammalian NADH-ubiquinone oxidoreductase (Complex I). Biophysical Journal. 99: 1426-36. PMID 20816054 DOI: 10.1016/J.Bpj.2010.06.063 |
0.341 |
|
2010 |
Li X, Dash RK, Pradhan RK, Qi F, Thompson M, Vinnakota KC, Wu F, Yang F, Beard DA. A database of thermodynamic quantities for the reactions of glycolysis and the tricarboxylic acid cycle. The Journal of Physical Chemistry. B. 114: 16068-82. PMID 20446702 DOI: 10.1021/Jp911381P |
0.334 |
|
2010 |
Bugenhagen SM, Cowley AW, Beard DA. Identifying physiological origins of baroreflex dysfunction in salt-sensitive hypertension in the Dahl SS rat. Physiological Genomics. 42: 23-41. PMID 20354102 DOI: 10.1152/Physiolgenomics.00027.2010 |
0.765 |
|
2010 |
Pradhan RK, Beard DA, Dash RK. A biophysically based mathematical model for the kinetics of mitochondrial Na+-Ca2+ antiporter. Biophysical Journal. 98: 218-30. PMID 20338843 DOI: 10.1016/J.Bpj.2009.10.005 |
0.308 |
|
2009 |
Xie D, Dash RK, Beard DA. An Improved Algorithm and Its Parallel Implementation for Solving a General Blood-Tissue Transport and Metabolism Model. Journal of Computational Physics. 228: 7850-7861. PMID 20161089 DOI: 10.1016/J.Jcp.2009.07.024 |
0.307 |
|
2009 |
Beard DA, Kushmerick MJ. Strong inference for systems biology. Plos Computational Biology. 5: e1000459. PMID 19714210 DOI: 10.1371/Journal.Pcbi.1000459 |
0.323 |
|
2009 |
Beard DA, Britten R, Cooling MT, Garny A, Halstead MD, Hunter PJ, Lawson J, Lloyd CM, Marsh J, Miller A, Nickerson DP, Nielsen PM, Nomura T, Subramanium S, Wimalaratne SM, et al. CellML metadata standards, associated tools and repositories. Philosophical Transactions. Series a, Mathematical, Physical, and Engineering Sciences. 367: 1845-67. PMID 19380315 DOI: 10.1098/Rsta.2008.0310 |
0.359 |
|
2009 |
Wu F, Zhang J, Beard DA. Experimentally observed phenomena on cardiac energetics in heart failure emerge from simulations of cardiac metabolism. Proceedings of the National Academy of Sciences of the United States of America. 106: 7143-8. PMID 19357309 DOI: 10.1073/Pnas.0812768106 |
0.354 |
|
2009 |
Wu F, Beard DA. Roles of the creatine kinase system and myoglobin in maintaining energetic state in the working heart. Bmc Systems Biology. 3: 22. PMID 19228404 DOI: 10.1186/1752-0509-3-22 |
0.366 |
|
2008 |
Secomb TW, Beard DA, Frisbee JC, Smith NP, Pries AR. The role of theoretical modeling in microcirculation research. Microcirculation (New York, N.Y. : 1994). 15: 693-8. PMID 18946803 DOI: 10.1080/10739680802349734 |
0.342 |
|
2008 |
Dash RK, Li Y, Kim J, Beard DA, Saidel GM, Cabrera ME. Metabolic dynamics in skeletal muscle during acute reduction in blood flow and oxygen supply to mitochondria: in-silico studies using a multi-scale, top-down integrated model. Plos One. 3: e3168. PMID 18779864 DOI: 10.1371/Journal.Pone.0003168 |
0.38 |
|
2008 |
Qi F, Chen X, Beard DA. Detailed kinetics and regulation of mammalian NAD-linked isocitrate dehydrogenase. Biochimica Et Biophysica Acta. 1784: 1641-51. PMID 18672100 DOI: 10.1016/J.Bbapap.2008.07.001 |
0.334 |
|
2008 |
Beard DA. Comment on 'Dynamic analysis of optimality in myocardial energy metabolism under normal and ischemic conditions'. Molecular Systems Biology. 4: 207; discussion 208. PMID 18628747 DOI: 10.1038/Msb.2008.37 |
0.302 |
|
2008 |
Wu F, Zhang EY, Zhang J, Bache RJ, Beard DA. Phosphate metabolite concentrations and ATP hydrolysis potential in normal and ischaemic hearts. The Journal of Physiology. 586: 4193-208. PMID 18617566 DOI: 10.1113/Jphysiol.2008.154732 |
0.385 |
|
2008 |
Beard DA, Wu F, Cabrera ME, Dash RK. Modeling of cellular metabolism and microcirculatory transport. Microcirculation (New York, N.Y. : 1994). 15: 777-93. PMID 18608987 DOI: 10.1080/10739680802019709 |
0.316 |
|
2008 |
Dash RK, Beard DA. Analysis of cardiac mitochondrial Na+-Ca2+ exchanger kinetics with a biophysical model of mitochondrial Ca2+ handling suggests a 3:1 stoichiometry. The Journal of Physiology. 586: 3267-85. PMID 18467367 DOI: 10.1113/Jphysiol.2008.151977 |
0.317 |
|
2007 |
Wu F, Yang F, Vinnakota KC, Beard DA. Computer modeling of mitochondrial tricarboxylic acid cycle, oxidative phosphorylation, metabolite transport, and electrophysiology. The Journal of Biological Chemistry. 282: 24525-37. PMID 17591785 DOI: 10.1074/Jbc.M701024200 |
0.396 |
|
2007 |
Smith NP, Crampin EJ, Niederer SA, Bassingthwaighte JB, Beard DA. Computational biology of cardiac myocytes: proposed standards for the physiome. The Journal of Experimental Biology. 210: 1576-83. PMID 17449822 DOI: 10.1242/Jeb.000133 |
0.546 |
|
2007 |
Beard DA, Qian H. Relationship between thermodynamic driving force and one-way fluxes in reversible processes. Plos One. 2: e144. PMID 17206279 DOI: 10.1371/Journal.Pone.0000144 |
0.301 |
|
2007 |
Wu F, Jeneson JA, Beard DA. Oxidative ATP synthesis in skeletal muscle is controlled by substrate feedback. American Journal of Physiology. Cell Physiology. 292: C115-24. PMID 16837647 DOI: 10.1152/Ajpcell.00237.2006 |
0.335 |
|
2006 |
Qian H, Beard DA. Metabolic futile cycles and their functions: a systems analysis of energy and control. Systems Biology. 153: 192-200. PMID 16986621 DOI: 10.1049/Ip-Syb:20050086 |
0.309 |
|
2006 |
Beard DA. Modeling of oxygen transport and cellular energetics explains observations on in vivo cardiac energy metabolism. Plos Computational Biology. 2: e107. PMID 16978045 DOI: 10.1371/Journal.Pcbi.0020107 |
0.398 |
|
2005 |
Beard DA, Bassingthwaighte JB, Greene AS. Computational modeling of physiological systems. Physiological Genomics. 23: 1-3; discussion 4. PMID 16179418 DOI: 10.1152/Physiolgenomics.00117.2005 |
0.499 |
|
2005 |
Beard DA. A biophysical model of the mitochondrial respiratory system and oxidative phosphorylation. Plos Computational Biology. 1: e36. PMID 16163394 DOI: 10.1371/Journal.Pcbi.0010036 |
0.388 |
|
2005 |
Qian H, Beard DA. Thermodynamics of stoichiometric biochemical networks in living systems far from equilibrium. Biophysical Chemistry. 114: 213-20. PMID 15829355 DOI: 10.1016/J.Bpc.2004.12.001 |
0.307 |
|
2005 |
Ejike JC, Arakaki LS, Beard DA, Ciesielski WA, Feigl EO, Schenkman KA. Myocardial oxygenation and adenosine release in isolated guinea pig hearts during changes in contractility. American Journal of Physiology. Heart and Circulatory Physiology. 288: H2062-7. PMID 15591100 DOI: 10.1152/Ajpheart.00777.2004 |
0.603 |
|
2005 |
Beard DA, Qian H. Thermodynamic-based computational profiling of cellular regulatory control in hepatocyte metabolism. American Journal of Physiology. Endocrinology and Metabolism. 288: E633-44. PMID 15507536 DOI: 10.1152/Ajpendo.00239.2004 |
0.313 |
|
2005 |
Beard DA. Integrated Computational Modeling of Oxygen Transport and Cellular Energetics Explains Observations on In Vivo Cardiac Oxygen Consumption and Energy Metabolites Plos Computational Biology. DOI: 10.1371/Journal.Pcbi.0020107.Eor |
0.317 |
|
2003 |
Beard DA, Schenkman KA, Feigl EO. Myocardial oxygenation in isolated hearts predicted by an anatomically realistic microvascular transport model. American Journal of Physiology. Heart and Circulatory Physiology. 285: H1826-36. PMID 12869375 DOI: 10.1152/Ajpheart.00380.2003 |
0.606 |
|
2003 |
Schenkman KA, Beard DA, Ciesielski WA, Feigl EO. Comparison of buffer and red blood cell perfusion of guinea pig heart oxygenation. American Journal of Physiology. Heart and Circulatory Physiology. 285: H1819-25. PMID 12869374 DOI: 10.1152/Ajpheart.00383.2003 |
0.598 |
|
2001 |
Bassingthwaighte JB, Beard DA, Li Z. The mechanical and metabolic basis of myocardial blood flow heterogeneity. Basic Research in Cardiology. 96: 582-94. PMID 11770077 DOI: 10.1007/S003950170010 |
0.524 |
|
2001 |
Beard DA. Computational framework for generating transport models from databases of microvascular anatomy. Annals of Biomedical Engineering. 29: 837-43. PMID 11764314 DOI: 10.1114/1.1408920 |
0.306 |
|
2001 |
Beard DA, Bassingthwaighte JB. Modeling advection and diffusion of oxygen in complex vascular networks. Annals of Biomedical Engineering. 29: 298-310. PMID 11339327 DOI: 10.1114/1.1359450 |
0.531 |
|
2000 |
Beard DA, Bassingthwaighte JB. The fractal nature of myocardial blood flow emerges from a whole-organ model of arterial network. Journal of Vascular Research. 37: 282-96. PMID 10965227 DOI: 10.1159/000025742 |
0.537 |
|
2000 |
Beard DA, Bassingthwaighte JB. Advection and diffusion of substances in biological tissues with complex vascular networks. Annals of Biomedical Engineering. 28: 253-68. PMID 10784090 DOI: 10.1114/1.273 |
0.555 |
|
2000 |
Karch R, Neumann F, Neumann M, Schreiner W, Dawes M, Ritter JM, Axel DI, Spyridopoulos I, Riessen R, Runge H, Viebahn R, Karsch KR, Keravis T, Komas N, Lugnier C, ... ... Beard DA, et al. Author Index (Abstracts only) Journal of Vascular Research. 37: 340-341. DOI: 10.1159/000025746 |
0.443 |
|
2000 |
Karch R, Neumann F, Neumann M, Schreiner W, Dawes M, Ritter JM, Axel DI, Spyridopoulos I, Riessen R, Runge H, Viebahn R, Karsch KR, Keravis T, Komas N, Lugnier C, ... ... Beard DA, et al. Annual Meeting of the Deutsche Gesellschaft für Mikrozirkulation und Vaskuläre Biologie e.V. Journal of Vascular Research. 37: 305-339. DOI: 10.1159/000025745 |
0.451 |
|
2000 |
Karch R, Neumann F, Neumann M, Schreiner W, Dawes M, Ritter JM, Axel DI, Spyridopoulos I, Riessen R, Runge H, Viebahn R, Karsch KR, Keravis T, Komas N, Lugnier C, ... ... Beard DA, et al. Internet Discussion Forum Journal of Vascular Research. 37: 303-304. DOI: 10.1159/000025744 |
0.445 |
|
1998 |
Beard DA, Bassingthwaighte JB. Power-law kinetics of tracer washout from physiological systems. Annals of Biomedical Engineering. 26: 775-9. PMID 9779949 DOI: 10.1114/1.105 |
0.503 |
|
1995 |
Bassingthwaighte JB, Beard DA. Fractal 15O-labeled water washout from the heart. Circulation Research. 77: 1212-21. PMID 7586234 DOI: 10.1161/01.Res.77.6.1212 |
0.523 |
|
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