Richard L. Klemke, Ph.D. - Publications

Affiliations: 
Pathology University of California, San Diego, La Jolla, CA 
Area:
Cancer

81 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Baba SA, Sun Q, Mugisha S, Labhsetwar S, Klemke R, Desgrosellier JS. Breast cancer stem cells tolerate chromosomal instability during tumor progression via c-Jun/AXL stress signaling. Heliyon. 9: e20182. PMID 37809421 DOI: 10.1016/j.heliyon.2023.e20182  0.325
2021 Sahu D, Huan J, Wang H, Sahoo D, Casteel DE, Klemke RL, Boss GR, Hansel DE. Bladder Cancer Invasion is Mediated by mTORC2-Driven Regulation of Nitric Oxide and Invadopodia Formation. The American Journal of Pathology. PMID 34428425 DOI: 10.1016/j.ajpath.2021.08.002  0.345
2019 Klemke RL, Wang H, Liu B, Alarcon C, Watson F. Abstract LB-067: Cargocytes: A novel cell therapy platform to drive anti-tumor immunity Cancer Research. 79. DOI: 10.1158/1538-7445.Am2019-Lb-067  0.463
2018 Strnadel J, Wang H, Carromeu C, Miyanohara A, Fujimura K, Blahovcova E, Nosal V, Skovierova H, Klemke R, Halasova E. Transplantation of Human-Induced Pluripotent Stem Cell-Derived Neural Precursors into Early-Stage Zebrafish Embryos. Journal of Molecular Neuroscience : Mn. PMID 30003430 DOI: 10.1007/S12031-018-1109-Z  0.355
2018 Wang H, Lapek J, Fujimura K, Strnadel J, Liu B, Gonzalez DJ, Zhang W, Watson F, Yu V, Liu C, Melo CM, Miller YI, Elliott KC, Cheresh DA, Klemke RL. Pseudopodium-enriched atypical kinase 1 mediates angiogenesis by modulating GATA2-dependent VEGFR2 transcription. Cell Discovery. 4: 26. PMID 29872538 DOI: 10.1038/S41421-018-0024-3  0.662
2018 Liu C, Han T, Stachura DL, Wang H, Vaisman BL, Kim J, Klemke RL, Remaley AT, Rana TM, Traver D, Miller YI. Lipoprotein lipase regulates hematopoietic stem progenitor cell maintenance through DHA supply. Nature Communications. 9: 1310. PMID 29615667 DOI: 10.1038/S41467-018-03775-Y  0.311
2018 Gilder AS, Natali L, Van Dyk DM, Zalfa C, Banki MA, Pizzo DP, Wang H, Klemke RL, Mantuano E, Gonias SL. The Urokinase Receptor Induces a Mesenchymal Gene Expression Signature in Glioblastoma Cells and Promotes Tumor Cell Survival in Neurospheres. Scientific Reports. 8: 2982. PMID 29445239 DOI: 10.1038/S41598-018-21358-1  0.457
2018 Guerra HN, Cruz MC, Ribeiro PRL, Strnadel J, Wang H, Klemke RL, Jaeger RG, Freitas VM. ADAMTS-1 disrupts HGF/c-MET signaling and HGF-stimulated cellular processes in fibrosarcoma. Experimental Cell Research. PMID 29355494 DOI: 10.1016/J.Yexcr.2018.01.017  0.415
2018 Fujimura K, Wang H, Watson F, Klemke RL. KRAS oncoprotein expression is regulated by a self-governing eIF5A-PEAK1 feed-forward regulatory loop. Cancer Research. PMID 29321164 DOI: 10.1158/0008-5472.Can-17-2873  0.513
2018 Sahu D, Hansel DE, Klemke R, Boss G. Role of mTORC2 and nitric oxide in bladder cancer invasion. Journal of Clinical Oncology. 36: 504-504. DOI: 10.1200/Jco.2018.36.6_Suppl.504  0.449
2017 Strnadel J, Choi S, Fujimura K, Wang H, Zhang W, Wyse M, Wright T, Gross E, Peinado C, Park HW, Bui J, Kelber J, Bouvet M, Guan KL, Klemke RL. eIF5A-PEAK1 Signaling Regulates YAP1/TAZ Protein Expression and Pancreatic Cancer Cell Growth. Cancer Research. PMID 28381547 DOI: 10.1158/0008-5472.Can-16-2594  0.687
2017 Klemke RL. Abstract 1811: A PEAK1/GATA2 signaling axis controls VEGFR2 expression to mediate angiogenesis Cancer Research. 77: 1811-1811. DOI: 10.1158/1538-7445.Am2017-1811  0.338
2015 Fujimura K, Choi S, Wyse M, Strnadel J, Wright T, Klemke R. Eukaryotic Translation Initiation Factor 5A (EIF5A) Regulates Pancreatic Cancer Metastasis by Modulating RhoA and Rho-associated Kinase (ROCK) Protein Expression Levels. The Journal of Biological Chemistry. PMID 26483550 DOI: 10.1074/Jbc.M115.687418  0.508
2015 Agajanian M, Campeau A, Hoover M, Hou A, Brambilla D, Kim SL, Klemke RL, Kelber JA. PEAK1 Acts as a Molecular Switch to Regulate Context-Dependent TGFβ Responses in Breast Cancer. Plos One. 10: e0135748. PMID 26267863 DOI: 10.1371/Journal.Pone.0135748  0.746
2015 Pasillas MP, Shields S, Reilly R, Strnadel J, Behl C, Park R, Yates JR, Klemke R, Gonias SL, Coppinger JA. Proteomic analysis reveals a role for Bcl2-associated athanogene 3 and major vault protein in resistance to apoptosis in senescent cells by regulating ERK1/2 activation. Molecular & Cellular Proteomics : McP. 14: 1-14. PMID 24997994 DOI: 10.1074/Mcp.M114.037697  0.463
2014 Fujimura K, Wright T, Strnadel J, Kaushal S, Metildi C, Lowy AM, Bouvet M, Kelber JA, Klemke RL. A hypusine-eIF5A-PEAK1 switch regulates the pathogenesis of pancreatic cancer. Cancer Research. 74: 6671-81. PMID 25261239 DOI: 10.1158/0008-5472.Can-14-1031  0.675
2014 Spike BT, Kelber JA, Booker E, Kalathur M, Rodewald R, Lipianskaya J, La J, He M, Wright T, Klemke R, Wahl GM, Gray PC. CRIPTO/GRP78 signaling maintains fetal and adult mammary stem cells ex vivo. Stem Cell Reports. 2: 427-39. PMID 24749068 DOI: 10.1016/J.Stemcr.2014.02.010  0.622
2014 Choi S, Kelber J, Jiang X, Strnadel J, Fujimura K, Pasillas M, Coppinger J, Klemke R. Procedures for the biochemical enrichment and proteomic analysis of the cytoskeletome. Analytical Biochemistry. 446: 102-7. PMID 24161902 DOI: 10.1016/J.Ab.2013.10.025  0.607
2014 Fujimura K, Wright T, Strnadel J, Kelber J, Kaushal S, Metildi C, Lowy A, Bouvet M, Klemke R. Abstract LB-303: A hypusine-eIF5A-PEAK1 switch regulates the pathogenesis of pancreatic ductal adenocarcinoma Cancer Research. 74. DOI: 10.1158/1538-7445.Am2014-Lb-303  0.662
2014 Spike BT, Kelber JA, Booker E, Kalathur M, Rodewald R, Lipianskaya J, La J, He M, Wright T, Klemke R, Wahl G, Gray PC. Abstract 3035: Cripto/GRP78 signaling promotes the stem cell phenotype in normal and neoplastic mammary epithelial cells Cancer Research. 74: 3035-3035. DOI: 10.1158/1538-7445.Am2014-3035  0.687
2013 Klemke RL, Jiang X, Choi S, Kelber JA. Proteomic and biochemical methods to study the cytoskeletome. Methods in Molecular Biology (Clifton, N.J.). 1046: 203-18. PMID 23868590 DOI: 10.1007/978-1-62703-538-5_12  0.631
2013 Stoletov K, Strnadel J, Zardouzian E, Momiyama M, Park FD, Kelber JA, Pizzo DP, Hoffman R, VandenBerg SR, Klemke RL. Role of connexins in metastatic breast cancer and melanoma brain colonization. Journal of Cell Science. 126: 904-13. PMID 23321642 DOI: 10.1242/Jcs.112748  0.627
2013 Bristow JM, Reno TA, Jo M, Gonias SL, Klemke RL. Dynamic phosphorylation of tyrosine 665 in pseudopodium-enriched atypical kinase 1 (PEAK1) is essential for the regulation of cell migration and focal adhesion turnover. The Journal of Biological Chemistry. 288: 123-31. PMID 23105102 DOI: 10.1074/Jbc.M112.410910  0.473
2013 Metildi CA, Kaushal S, Strnadel J, Wright T, Kelber JA, Klemke RL, Hoffman RM, Bouvet M. Abstract 4911: Aggressive variants isolated from human pancreatic cancer passaging in mice are enriched in stem cell markers and PEAK1 expression. Cancer Research. 73: 4911-4911. DOI: 10.1158/1538-7445.Am2013-4911  0.642
2013 Metildi C, Kaushal S, Strnadel J, Wright T, Kelber J, Klemke R, Hoffman R, Bouvet M. Serial In Vivo Passaging of Human Pancreatic Tumors in Nude Mice Results in Aggressive Variants Enriched in Stem Cell Markers and PEAK1 Expression Journal of Surgical Research. 179: 240. DOI: 10.1016/J.Jss.2012.10.447  0.612
2012 Klemke RL. Trespassing cancer cells: 'fingerprinting' invasive protrusions reveals metastatic culprits. Current Opinion in Cell Biology. 24: 662-9. PMID 22980730 DOI: 10.1016/J.Ceb.2012.08.005  0.468
2012 Soman P, Kelber JA, Lee JW, Wright TN, Vecchio KS, Klemke RL, Chen S. Cancer cell migration within 3D layer-by-layer microfabricated photocrosslinked PEG scaffolds with tunable stiffness. Biomaterials. 33: 7064-70. PMID 22809641 DOI: 10.1016/J.Biomaterials.2012.06.012  0.61
2012 Kelber JA, Reno T, Kaushal S, Metildi C, Wright T, Stoletov K, Weems JM, Park FD, Mose E, Wang Y, Hoffman RM, Lowy AM, Bouvet M, Klemke RL. KRas induces a Src/PEAK1/ErbB2 kinase amplification loop that drives metastatic growth and therapy resistance in pancreatic cancer. Cancer Research. 72: 2554-64. PMID 22589274 DOI: 10.1158/0008-5472.Can-11-3552  0.669
2012 Wang Y, Klemke RL. Proteomics method for identification of pseudopodium phosphotyrosine proteins. Methods in Molecular Biology (Clifton, N.J.). 757: 349-65. PMID 21909922 DOI: 10.1007/978-1-61779-166-6_21  0.467
2012 Weems JM, Reno TA, Klemke RL. Abstract 914: Ciclopirox olamine (CPX) inhibits breast cancer cell proliferation by blocking the formation of a PEAK1-Src-eIF5a protein complex Cancer Research. 72: 914-914. DOI: 10.1158/1538-7445.Am2012-914  0.537
2012 Kelber JA, Reno T, Kaushal S, Metildi C, Stoletov K, Weems J, Park FD, Wright T, Mose E, Hoffman RM, Lowy AM, Bouvet MM, Klemke RL. Abstract 4167: KRas induces a Src/PEAK1/ErbB2 kinase amplification loop to drive pancreatic cancer growth, metastasis and therapy resistance Cancer Research. 72: 4167-4167. DOI: 10.1158/1538-7445.Am2012-4167  0.678
2012 Spike BT, Kelber JA, Kalathur M, Booker E, Lipianskaya J, Klemke R, Vale W, Wahl G, Gray PC. Abstract 3493: Soluble ALK4 extracellular domain antagonizes the cancer/stem cell phenotype caused by Nodal and Cripto signaling in mammary epithelia Cancer Research. 72: 3493-3493. DOI: 10.1158/1538-7445.Am2012-3493  0.743
2012 Metildi CA, Kaushal S, Kelber J, Wright T, Snyder CS, Klemke R, Hoffman RM, Bouvet M. Abstract 3375: In vivo passaging of primary pancreatic tumor enriches for stem cells and PEAK expression Cancer Research. 72: 3375-3375. DOI: 10.1158/1538-7445.Am2012-3375  0.638
2011 Wang Y, Yang F, Fu Y, Huang X, Wang W, Jiang X, Gritsenko MA, Zhao R, Monore ME, Pertz OC, Purvine SO, Orton DJ, Jacobs JM, Camp DG, Smith RD, ... Klemke RL, et al. Spatial phosphoprotein profiling reveals a compartmentalized extracellular signal-regulated kinase switch governing neurite growth and retraction. The Journal of Biological Chemistry. 286: 18190-201. PMID 21454597 DOI: 10.1074/Jbc.M111.236133  0.406
2011 Weems JM, Klemke RL. Abstract 4464: Ciclopirox Olamine alters PEAK-1-mediated cytoskeleton organization and invasion of metastatic cancer cells Cancer Research. 71: 4464-4464. DOI: 10.1158/1538-7445.Am2011-4464  0.518
2011 Kelber JA, Klemke RL. The Actin Cytoskeleton Cellular Domains. 197-212. DOI: 10.1002/9781118015759.ch12  0.49
2010 Kelber JA, Klemke RL. PEAK1, a novel kinase target in the fight against cancer. Oncotarget. 1: 219-23. PMID 21301050 DOI: 10.18632/Oncotarget.128  0.59
2010 Jo M, Eastman BM, Webb DL, Stoletov K, Klemke R, Gonias SL. Cell signaling by urokinase-type plasminogen activator receptor induces stem cell-like properties in breast cancer cells. Cancer Research. 70: 8948-58. PMID 20940399 DOI: 10.1158/0008-5472.Can-10-1936  0.505
2010 Jin H, Garmy-Susini B, Avraamides CJ, Stoletov K, Klemke RL, Varner JA. A PKA-Csk-pp60Src signaling pathway regulates the switch between endothelial cell invasion and cell-cell adhesion during vascular sprouting. Blood. 116: 5773-83. PMID 20826718 DOI: 10.1182/Blood-2010-07-296210  0.462
2010 Wang Y, Kelber JA, Tran Cao HS, Cantin GT, Lin R, Wang W, Kaushal S, Bristow JM, Edgington TS, Hoffman RM, Bouvet M, Yates JR, Klemke RL. Pseudopodium-enriched atypical kinase 1 regulates the cytoskeleton and cancer progression [corrected]. Proceedings of the National Academy of Sciences of the United States of America. 107: 10920-5. PMID 20534451 DOI: 10.1073/Pnas.0914776107  0.696
2010 Stoletov K, Kato H, Zardouzian E, Kelber J, Yang J, Shattil S, Klemke R. Visualizing extravasation dynamics of metastatic tumor cells. Journal of Cell Science. 123: 2332-41. PMID 20530574 DOI: 10.1242/Jcs.069443  0.664
2010 Murphy EA, Shields DJ, Stoletov K, Dneprovskaia E, McElroy M, Greenberg JI, Lindquist J, Acevedo LM, Anand S, Majeti BK, Tsigelny I, Saldanha A, Walsh B, Hoffman RM, Bouvet M, ... Klemke RL, et al. Disruption of angiogenesis and tumor growth with an orally active drug that stabilizes the inactive state of PDGFRbeta/B-RAF. Proceedings of the National Academy of Sciences of the United States of America. 107: 4299-304. PMID 20154271 DOI: 10.1073/Pnas.0909299107  0.614
2010 Spike BT, Kelber JA, Booker EC, Klemke RL, Wahl GM, Vale WW, Gray PC. Abstract 4006: Soluble ALK4 extracellular domain antagonizes oncogenic Cripto signaling and inhibits tumor growth Cancer Research. 70: 4006-4006. DOI: 10.1158/1538-7445.Am10-4006  0.663
2010 Wang Y, Kelber JA, Tran Cao HS, Cantin GT, Lin R, Wang W, Kaushal S, Bristow JM, Edgington TS, Hoffman RM, Bouvet M, Yates JR, Klemke RL. Pseudopodium-enriched atypical kinase 1 regulates the cytoskeleton and cancer progession (Proceedings of the National Academy of Sciences of the United States of America (2010) 107, 24 (10920-10925) DOI: 10.1073/pnas.0914776107) Proceedings of the National Academy of Sciences of the United States of America. 107: 13556. DOI: 10.1073/Pnas.1008849107  0.596
2009 Green CE, Liu T, Montel V, Hsiao G, Lester RD, Subramaniam S, Gonias SL, Klemke RL. Chemoattractant signaling between tumor cells and macrophages regulates cancer cell migration, metastasis and neovascularization. Plos One. 4: e6713. PMID 19696929 DOI: 10.1371/Journal.Pone.0006713  0.455
2009 Stoletov K, Fang L, Choi SH, Hartvigsen K, Hansen LF, Hall C, Pattison J, Juliano J, Miller ER, Almazan F, Crosier P, Witztum JL, Klemke RL, Miller YI. Vascular lipid accumulation, lipoprotein oxidation, and macrophage lipid uptake in hypercholesterolemic zebrafish. Circulation Research. 104: 952-60. PMID 19265037 DOI: 10.1161/Circresaha.108.189803  0.314
2008 Ding SJ, Wang Y, Jacobs JM, Qian WJ, Yang F, Tolmachev AV, Du X, Wang W, Moore RJ, Monroe ME, Purvine SO, Waters K, Heibeck TH, Adkins JN, Camp DG, ... Klemke RL, et al. Quantitative phosphoproteome analysis of lysophosphatidic acid induced chemotaxis applying dual-step (18)O labeling coupled with immobilized metal-ion affinity chromatography. Journal of Proteome Research. 7: 4215-24. PMID 18785766 DOI: 10.1021/Pr7007785  0.334
2008 Stoletov K, Klemke R. Catch of the day: Zebrafish as a human cancer model Oncogene. 27: 4509-4520. PMID 18372910 DOI: 10.1038/Onc.2008.95  0.349
2008 Wrasidlo W, Mielgo A, Torres VA, Barbero S, Stoletov K, Suyama TL, Klemke RL, Gerwick WH, Carson DA, Stupack DG. The marine lipopeptide somocystinamide A triggers apoptosis via caspase 8. Proceedings of the National Academy of Sciences of the United States of America. 105: 2313-8. PMID 18268346 DOI: 10.1073/Pnas.0712198105  0.401
2008 Pertz OC, Wang Y, Yang F, Wang W, Gay LJ, Gristenko MA, Clauss TR, Anderson DJ, Liu T, Auberry KJ, Camp DG, Smith RD, Klemke RL. Spatial mapping of the neurite and soma proteomes reveals a functional Cdc42/Rac regulatory network. Proceedings of the National Academy of Sciences of the United States of America. 105: 1931-6. PMID 18245386 DOI: 10.1073/Pnas.0706545105  0.37
2008 Wang Y, Klemke RL. PhosphoBlast, a computational tool for comparing phosphoprotein signatures among large datasets. Molecular & Cellular Proteomics : McP. 7: 145-62. PMID 17934212 DOI: 10.1074/Mcp.M700207-Mcp200  0.343
2008 Klemke R, Stoletov K, Montel V, Lester R, Gonias S. Signaling mechanisms of tumor cell migration and metastasis European Journal of Cancer Supplements. 6: 62. DOI: 10.1016/S1359-6349(08)71411-3  0.354
2007 Stoletov K, Montel V, Lester RD, Gonias SL, Klemke R. High-resolution imaging of the dynamic tumor cell-vascular interface in transparent zebrafish Proceedings of the National Academy of Sciences of the United States of America. 104: 17406-17411. PMID 17954920 DOI: 10.1073/Pnas.0703446104  0.484
2007 Wang Y, Ding SJ, Wang W, Yang F, Jacobs JM, Camp D, Smith RD, Klemke RL. Methods for pseudopodia purification and proteomic analysis. Science's Stke : Signal Transduction Knowledge Environment. 2007: pl4. PMID 17712138 DOI: 10.1126/Stke.4002007Pl4  0.456
2007 Wang Y, Ding SJ, Wang W, Jacobs JM, Qian WJ, Moore RJ, Yang F, Camp DG, Smith RD, Klemke RL. Profiling signaling polarity in chemotactic cells. Proceedings of the National Academy of Sciences of the United States of America. 104: 8328-33. PMID 17494752 DOI: 10.1073/Pnas.0701103104  0.377
2007 Wang Y, Klemke RL. Biochemical purification of pseudopodia from migratory cells. Methods in Molecular Biology (Clifton, N.J.). 370: 55-66. PMID 17416987 DOI: 10.1007/978-1-59745-353-0_5  0.44
2006 Wang Y, Hanley R, Klemke RL. Computational methods for comparison of large genomic and proteomic datasets reveal protein markers of metastatic cancer. Journal of Proteome Research. 5: 907-15. PMID 16602698 DOI: 10.1021/Pr050390U  0.385
2006 Pertz O, Hodgson L, Klemke RL, Hahn KM. Spatiotemporal dynamics of RhoA activity in migrating cells. Nature. 440: 1069-72. PMID 16547516 DOI: 10.1038/Nature04665  0.416
2006 Holcomb M, Rufini A, Barilà D, Klemke RL. Deregulation of proteasome function induces Abl-mediated cell death by uncoupling p130CAS and c-CrkII. The Journal of Biological Chemistry. 281: 2430-40. PMID 16267043 DOI: 10.1074/Jbc.M508454200  0.436
2005 Wozniak MA, Kwong L, Chodniewicz D, Klemke RL, Keely PJ. R-Ras controls membrane protrusion and cell migration through the spatial regulation of Rac and Rho. Molecular Biology of the Cell. 16: 84-96. PMID 15525681 DOI: 10.1091/Mbc.E04-04-0277  0.322
2004 Chodniewicz D, Klemke RL. Guiding cell migration through directed extension and stabilization of pseudopodia. Experimental Cell Research. 301: 31-7. PMID 15501442 DOI: 10.1016/J.Yexcr.2004.08.006  0.409
2004 Chodniewicz D, Klemke RL. Regulation of integrin-mediated cellular responses through assembly of a CAS/Crk scaffold. Biochimica Et Biophysica Acta. 1692: 63-76. PMID 15246680 DOI: 10.1016/J.Bbamcr.2004.03.006  0.422
2004 Lin YH, Park ZY, Lin D, Brahmbhatt AA, Rio MC, Yates JR, Klemke RL. Regulation of cell migration and survival by focal adhesion targeting of Lasp-1. The Journal of Cell Biology. 165: 421-32. PMID 15138294 DOI: 10.1083/Jcb.200311045  0.504
2003 Kain KH, Gooch S, Klemke RL. Cytoplasmic c-Abl provides a molecular 'Rheostat' controlling carcinoma cell survival and invasion. Oncogene. 22: 6071-80. PMID 12955086 DOI: 10.1038/Sj.Onc.1206930  0.435
2003 Brahmbhatt AA, Klemke RL. ERK and RhoA differentially regulate pseudopodia growth and retraction during chemotaxis. The Journal of Biological Chemistry. 278: 13016-25. PMID 12571246 DOI: 10.1074/Jbc.M211873200  0.482
2002 Cho SY, Klemke RL. Purification of pseudopodia from polarized cells reveals redistribution and activation of Rac through assembly of a CAS/Crk scaffold. The Journal of Cell Biology. 156: 725-36. PMID 11839772 DOI: 10.1083/Jcb.200111032  0.389
2001 Ting AY, Kain KH, Klemke RL, Tsien RY. Genetically encoded fluorescent reporters of protein tyrosine kinase activities in living cells. Proceedings of the National Academy of Sciences of the United States of America. 98: 15003-8. PMID 11752449 DOI: 10.1073/Pnas.211564598  0.422
2001 Kain KH, Klemke RL. Inhibition of cell migration by Abl family tyrosine kinases through uncoupling of Crk-CAS complexes. The Journal of Biological Chemistry. 276: 16185-92. PMID 11279004 DOI: 10.1074/Jbc.M100095200  0.44
2000 Stupack DG, Cho SY, Klemke RL. Molecular signaling mechanisms of cell migration and invasion. Immunologic Research. 21: 83-8. PMID 10852105 DOI: 10.1385/Ir:21:2-3:83  0.501
2000 Li E, Stupack DG, Brown SL, Klemke R, Schlaepfer DD, Nemerow GR. Association of p130CAS with phosphatidylinositol-3-OH kinase mediates adenovirus cell entry. The Journal of Biological Chemistry. 275: 14729-35. PMID 10799562 DOI: 10.1074/Jbc.275.19.14729  0.346
2000 Cho SY, Klemke RL. Extracellular-regulated kinase activation and CAS/Crk coupling regulate cell migration and suppress apoptosis during invasion of the extracellular matrix. The Journal of Cell Biology. 149: 223-36. PMID 10747099 DOI: 10.1083/Jcb.149.1.223  0.474
2000 Spencer KS, Graus-Porta D, Leng J, Hynes NE, Klemke RL. ErbB2 is necessary for induction of carcinoma cell invasion by ErbB family receptor tyrosine kinases. The Journal of Cell Biology. 148: 385-97. PMID 10648571 DOI: 10.1083/Jcb.148.2.385  0.463
1999 Leng J, Klemke RL, Reddy AC, Cheresh DA. Potentiation of cell migration by adhesion-dependent cooperative signals from the GTPase Rac and Raf kinase. The Journal of Biological Chemistry. 274: 37855-61. PMID 10608850 DOI: 10.1074/Jbc.274.53.37855  0.657
1999 Cheresh DA, Leng J, Klemke RL. Regulation of cell contraction and membrane ruffling by distinct signals in migratory cells. The Journal of Cell Biology. 146: 1107-16. PMID 10477763 DOI: 10.1083/Jcb.146.5.1107  0.629
1998 Li E, Stupack D, Klemke R, Cheresh DA, Nemerow GR. Adenovirus endocytosis via α(v) integrins requires phosphoinositide-3- OH kinase Journal of Virology. 72: 2055-2061. PMID 9499060 DOI: 10.1128/Jvi.72.3.2055-2061.1998  0.615
1998 Eliceiri BP, Klemke R, Strömblad S, Cheresh DA. Integrin αvβ3 requirement for sustained mitogen-activated protein kinase activity during angiogenesis Journal of Cell Biology. 140: 1255-1263. PMID 9490736 DOI: 10.1097/00006982-199805000-00036  0.62
1998 Klemke RL, Leng J, Molander R, Brooks PC, Vuori K, Cheresh DA. CAS/Crk coupling serves as a "molecular switch" for induction of cell migration. The Journal of Cell Biology. 140: 961-72. PMID 9472046 DOI: 10.1083/Jcb.140.4.961  0.593
1997 Klemke RL, Cai S, Giannini AL, Gallagher PJ, de Lanerolle P, Cheresh DA. Regulation of cell motility by mitogen-activated protein kinase. The Journal of Cell Biology. 137: 481-92. PMID 9128257 DOI: 10.1083/Jcb.137.2.481  0.61
1997 Brooks PC, Klemke RL, Schon S, Lewis JM, Schwartz MA, Cheresh DA. Insulin-like growth factor receptor cooperates with integrin alpha v beta 5 to promote tumor cell dissemination in vivo. The Journal of Clinical Investigation. 99: 1390-8. PMID 9077549 DOI: 10.1172/Jci119298  0.605
1995 Brooks PC, Stromblad S, Klemke R, Visscher D, Sarkar FH, Cheresh DA. Antiintegrin αvβ3 blocks human breast cancer growth and angiogenesis in human skin Journal of Clinical Investigation. 96: 1815-1822. PMID 7560073 DOI: 10.1172/Jci118227  0.592
1994 Klemke RL, Yebra M, Bayna EM, Cheresh DA. Receptor tyrosine kinase signaling required for integrin alpha v beta 5-directed cell motility but not adhesion on vitronectin. The Journal of Cell Biology. 127: 859-66. PMID 7525598 DOI: 10.1083/Jcb.127.3.859  0.606
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