| Year |
Citation |
Score |
| 2023 |
Susanto TT, Hung V, Levine AG, Kerr CH, Yoo Y, Chen Y, Oses-Prieto JA, Fromm L, Fujii K, Wernig M, Burlingame AL, Ruggero D, Barna M. RAPIDASH: A tag-free enrichment of ribosome-associated proteins reveals compositional dynamics in embryonic tissues and stimulated macrophages. Biorxiv : the Preprint Server For Biology. PMID 38106052 DOI: 10.1101/2023.12.07.570613 |
0.733 |
|
| 2023 |
Schaukowitch K, Janas JA, Wernig M. Insights and applications of direct neuronal reprogramming. Current Opinion in Genetics & Development. 83: 102128. PMID 37862835 DOI: 10.1016/j.gde.2023.102128 |
0.391 |
|
| 2023 |
Guo MG, Reynolds DL, Ang CE, Liu Y, Zhao Y, Donohue LKH, Siprashvili Z, Yang X, Yoo Y, Mondal S, Hong A, Kain J, Meservey L, Fabo T, Elfaki I, ... ... Wernig M, et al. Integrative analyses highlight functional regulatory variants associated with neuropsychiatric diseases. Nature Genetics. PMID 37857935 DOI: 10.1038/s41588-023-01533-5 |
0.727 |
|
| 2023 |
Yoo Y, Neumayer G, Shibuya Y, Mader MM, Wernig M. A cell therapy approach to restore microglial Trem2 function in a mouse model of Alzheimer's disease. Cell Stem Cell. 30: 1392. PMID 37802040 DOI: 10.1016/j.stem.2023.08.011 |
0.743 |
|
| 2023 |
Vainorius G, Novatchkova M, Michlits G, Baar JC, Raupach C, Lee J, Yelagandula R, Wernig M, Elling U. Ascl1 and Ngn2 convert mouse embryonic stem cells to neurons via functionally distinct paths. Nature Communications. 14: 5341. PMID 37660160 DOI: 10.1038/s41467-023-40803-y |
0.471 |
|
| 2023 |
Liu Y, Wang J, Südhof TC, Wernig M. Efficient generation of functional neurons from mouse embryonic stem cells via neurogenin-2 expression. Nature Protocols. PMID 37596357 DOI: 10.1038/s41596-023-00863-2 |
0.487 |
|
| 2023 |
Yoo Y, Neumayer G, Shibuya Y, Marc-Daniel Mader M, Wernig M. A cell therapy approach to restore microglial Trem2 function in a mouse model of Alzheimer's disease. Cell Stem Cell. 30: 1043-1053.e6. PMID 37541210 DOI: 10.1016/j.stem.2023.07.006 |
0.758 |
|
| 2023 |
Mader MM, Napole A, Wu D, Shibuya Y, Scavetti A, Foltz A, Atkins M, Hahn O, Yoo Y, Danziger R, Tan C, Wyss-Coray T, Steinman L, Wernig M. Augmentation of a neuroprotective myeloid state by hematopoietic cell transplantation. Biorxiv : the Preprint Server For Biology. PMID 36945385 DOI: 10.1101/2023.03.10.532123 |
0.754 |
|
| 2023 |
Neumayer G, Torkelson JL, Li S, McCarthy K, Zhen HH, Vangipuram M, Jackow J, Rami A, Hansen C, Guo Z, Gaddam S, Pappalardo A, Li L, Cramer A, Roy KR, ... ... Wernig M, et al. A scalable, GMP-compatible, autologous organotypic cell therapy for Dystrophic Epidermolysis Bullosa. Biorxiv : the Preprint Server For Biology. PMID 36909618 DOI: 10.1101/2023.02.28.529447 |
0.325 |
|
| 2022 |
Haddad Derafshi B, Danko T, Chanda S, Batista PJ, Litzenburger U, Lee QY, Ng YH, Sebin A, Chang HY, Südhof TC, Wernig M. The autism risk factor CHD8 is a chromatin activator in human neurons and functionally dependent on the ERK-MAPK pathway effector ELK1. Scientific Reports. 12: 22425. PMID 36575212 DOI: 10.1038/s41598-022-23614-x |
0.393 |
|
| 2022 |
Janas JA, Zhang L, Luu JH, Demeter J, Meng L, Marro SG, Mall M, Mooney NA, Schaukowitch K, Ng YH, Yang N, Huang Y, Neumayer G, Gozani O, Elias JE, ... ... Wernig M, et al. Tip60-mediated H2A.Z acetylation promotes neuronal fate specification and bivalent gene activation. Molecular Cell. PMID 36417913 DOI: 10.1016/j.molcel.2022.11.002 |
0.758 |
|
| 2022 |
Tanabe K, Nobuta H, Yang N, Ang CE, Huie P, Jordan S, Oldham MC, Rowitch DH, Wernig M. Generation of functional human oligodendrocytes from dermal fibroblasts by direct lineage conversion. Development (Cambridge, England). 149. PMID 35748297 DOI: 10.1242/dev.199723 |
0.404 |
|
| 2022 |
Matheus F, Raveh T, Oro AE, Wernig M, Drukker M. Is hypoimmunogenic stem cell therapy safe in times of pandemics? Stem Cell Reports. PMID 35334219 DOI: 10.1016/j.stemcr.2022.02.014 |
0.327 |
|
| 2022 |
Shibuya Y, Kumar KK, Mader MM, Yoo Y, Ayala LA, Zhou M, Mohr MA, Neumayer G, Kumar I, Yamamoto R, Marcoux P, Liou B, Bennett FC, Nakauchi H, Sun Y, ... ... Wernig M, et al. Treatment of a genetic brain disease by CNS-wide microglia replacement. Science Translational Medicine. 14: eabl9945. PMID 35294256 DOI: 10.1126/scitranslmed.abl9945 |
0.796 |
|
| 2021 |
Ng YH, Chanda S, Janas JA, Yang N, Kokubu Y, Südhof TC, Wernig M. Efficient generation of dopaminergic induced neuronal cells with midbrain characteristics. Stem Cell Reports. PMID 34171286 DOI: 10.1016/j.stemcr.2021.05.017 |
0.431 |
|
| 2021 |
Pak C, Danko T, Mirabella VR, Wang J, Liu Y, Vangipuram M, Grieder S, Zhang X, Ward T, Huang YA, Jin K, Dexheimer P, Bardes E, Mitelpunkt A, Ma J, ... ... Wernig M, et al. Cross-platform validation of neurotransmitter release impairments in schizophrenia patient-derived -mutant neurons. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 34035170 DOI: 10.1073/pnas.2025598118 |
0.316 |
|
| 2021 |
Raj N, McEachin ZT, Harousseau W, Zhou Y, Zhang F, Merritt-Garza ME, Taliaferro JM, Kalinowska M, Marro SG, Hales CM, Berry-Kravis E, Wolf-Ochoa MW, Martinez-Cerdeño V, Wernig M, Chen L, et al. Cell-type-specific profiling of human cellular models of fragile X syndrome reveal PI3K-dependent defects in translation and neurogenesis. Cell Reports. 35: 108991. PMID 33852833 DOI: 10.1016/j.celrep.2021.108991 |
0.769 |
|
| 2021 |
Haag D, Mack N, Benites Goncalves da Silva P, Statz B, Clark J, Tanabe K, Sharma T, Jäger N, Jones DTW, Kawauchi D, Wernig M, Pfister SM. H3.3-K27M drives neural stem cell-specific gliomagenesis in a human iPSC-derived model. Cancer Cell. PMID 33545065 DOI: 10.1016/j.ccell.2021.01.005 |
0.349 |
|
| 2021 |
Saavedra L, Wallace K, Freudenrich T, Mall M, Mundy W, Davila J, Shafer T, Wernig M, Haag D. Comparison of Acute Effects of Neurotoxic Compounds on Network Activity in Human and Rodent Neural Cultures. Toxicological Sciences : An Official Journal of the Society of Toxicology. PMID 33537736 DOI: 10.1093/toxsci/kfab008 |
0.311 |
|
| 2020 |
Michowski W, Chick JM, Chu C, Kolodziejczyk A, Wang Y, Suski JM, Abraham B, Anders L, Day D, Dunkl LM, Li Cheong Man M, Zhang T, Laphanuwat P, Bacon NA, Liu L, ... ... Wernig M, et al. Cdk1 Controls Global Epigenetic Landscape in Embryonic Stem Cells. Molecular Cell. PMID 32240602 DOI: 10.1016/J.Molcel.2020.03.010 |
0.772 |
|
| 2020 |
Lee QY, Mall M, Chanda S, Zhou B, Sharma KS, Schaukowitch K, Adrian-Segarra JM, Grieder SD, Kareta MS, Wapinski OL, Ang CE, Li R, Südhof TC, Chang HY, Wernig M. Pro-neuronal activity of Myod1 due to promiscuous binding to neuronal genes. Nature Cell Biology. PMID 32231311 DOI: 10.1038/S41556-020-0490-3 |
0.37 |
|
| 2019 |
Mahmoudi S, Mancini E, Xu L, Moore A, Jahanbani F, Hebestreit K, Srinivasan R, Li X, Devarajan K, Prélot L, Ang CE, Shibuya Y, Benayoun BA, Chang ALS, Wernig M, et al. Heterogeneity in old fibroblasts is linked to variability in reprogramming and wound healing. Nature. 574: 553-558. PMID 31645721 DOI: 10.1038/S41586-019-1658-5 |
0.347 |
|
| 2019 |
Nobuta H, Yang N, Ng YH, Marro SG, Sabeur K, Chavali M, Stockley JH, Killilea DW, Walter PB, Zhao C, Huie P, Goldman SA, Kriegstein AR, Franklin RJM, Rowitch DH, ... Wernig M, et al. Oligodendrocyte Death in Pelizaeus-Merzbacher Disease Is Rescued by Iron Chelation. Cell Stem Cell. 25: 531-541.e6. PMID 31585094 DOI: 10.1016/J.Stem.2019.09.003 |
0.724 |
|
| 2019 |
Huang YA, Zhou B, Nabet AM, Wernig M, Südhof TC. Differential Signaling Mediated by ApoE2, ApoE3, and ApoE4 in Human Neurons Parallels Alzheimer's Disease Risk. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 31331998 DOI: 10.1523/Jneurosci.2994-18.2019 |
0.36 |
|
| 2019 |
Marro SG, Chanda S, Yang N, Janas JA, Valperga G, Trotter J, Zhou B, Merrill S, Yousif I, Shelby H, Vogel H, Kalani MYS, Südhof TC, Wernig M. Neuroligin-4 Regulates Excitatory Synaptic Transmission in Human Neurons. Neuron. PMID 31257103 DOI: 10.1016/J.Neuron.2019.05.043 |
0.757 |
|
| 2019 |
Essayan-Perez S, Zhou B, Nabet AM, Wernig M, Huang YA. Modeling Alzheimer's disease with human iPS cells: advancements, lessons, and applications. Neurobiology of Disease. 104503. PMID 31202913 DOI: 10.1016/J.Nbd.2019.104503 |
0.444 |
|
| 2019 |
Chanda S, Ang CE, Lee QY, Ghebrial M, Haag D, Shibuya Y, Wernig M, Südhof TC. Direct Reprogramming of Human Neurons Identifies MARCKSL1 as a Pathogenic Mediator of Valproic Acid-Induced Teratogenicity. Cell Stem Cell. PMID 31155484 DOI: 10.1016/J.Stem.2019.04.021 |
0.458 |
|
| 2019 |
Li L, Wang Y, Torkelson JL, Shankar G, Pattison JM, Zhen HH, Fang F, Duren Z, Xin J, Gaddam S, Melo SP, Piekos SN, Li J, Liaw EJ, Chen L, ... ... Wernig M, et al. TFAP2C- and p63-Dependent Networks Sequentially Rearrange Chromatin Landscapes to Drive Human Epidermal Lineage Commitment. Cell Stem Cell. PMID 30686763 DOI: 10.1016/J.Stem.2018.12.012 |
0.412 |
|
| 2019 |
Luo C, Lee QY, Wapinski O, Castanon R, Nery JR, Mall M, Kareta MS, Cullen SM, Goodell MA, Chang HY, Wernig M, Ecker JR. Global DNA methylation remodeling during direct reprogramming of fibroblasts to neurons. Elife. 8. PMID 30644360 DOI: 10.7554/Elife.40197 |
0.421 |
|
| 2019 |
Ang CE, Ma Q, Wapinski OL, Fan S, Flynn RA, Lee QY, Coe B, Onoguchi M, Olmos VH, Do BT, Dukes-Rimsky L, Xu J, Tanabe K, Wang L, Elling U, ... ... Wernig M, et al. The novel lncRNA is pro-neurogenic and mutated in human neurodevelopmental disorders. Elife. 8. PMID 30628890 DOI: 10.7554/Elife.41770 |
0.465 |
|
| 2019 |
Purmann C, Zhang X, Pak C, Huang Y, Pattni R, Grieder S, Wernig M, Levinson D, Aronow B, Sudhof T, Urban A. M12 Approaches To Transcriptome Analysis Of Human Induced Neurons In Co-Culture With Murine Glia To Model Functional Synapses European Neuropsychopharmacology. 29. DOI: 10.1016/J.Euroneuro.2019.08.112 |
0.357 |
|
| 2018 |
Liu Y, Yu C, Daley TP, Wang F, Cao WS, Bhate S, Lin X, Still C, Liu H, Zhao D, Wang H, Xie XS, Ding S, Wong WH, Wernig M, et al. CRISPR Activation Screens Systematically Identify Factors that Drive Neuronal Fate and Reprogramming. Cell Stem Cell. PMID 30318302 DOI: 10.1016/J.Stem.2018.09.003 |
0.454 |
|
| 2018 |
Zhang Z, Marro SG, Zhang Y, Arendt KL, Patzke C, Zhou B, Fair T, Yang N, Südhof TC, Wernig M, Chen L. The fragile X mutation impairs homeostatic plasticity in human neurons by blocking synaptic retinoic acid signaling. Science Translational Medicine. 10. PMID 30068571 DOI: 10.1126/Scitranslmed.Aar4338 |
0.761 |
|
| 2018 |
Ang CE, Wernig M. Profiling DNA-transcription factor interactions. Nature Biotechnology. 36: 501-502. PMID 29874211 DOI: 10.1038/Nbt.4161 |
0.319 |
|
| 2018 |
Tanabe K, Ang CE, Chanda S, Olmos VH, Haag D, Levinson DF, Südhof TC, Wernig M. Transdifferentiation of human adult peripheral blood T cells into neurons. Proceedings of the National Academy of Sciences of the United States of America. PMID 29866841 DOI: 10.1073/Pnas.1720273115 |
0.539 |
|
| 2018 |
Luo C, Lee QY, Wapinski O, Castanon R, Nery JR, Mall M, Kareta MS, Cullen SM, Goodell MA, Chang HY, Wernig M, Ecker JR. Author response: Global DNA methylation remodeling during direct reprogramming of fibroblasts to neurons Elife. DOI: 10.7554/Elife.40197.020 |
0.309 |
|
| 2018 |
Pak C, Grieder S, Yang N, Zhang Y, Wernig M, Sudhof T. Rapid generation of functional and homogeneous excitatory human forebrain neurons using Neurogenin-2 (Ngn2) Protocol Exchange. DOI: 10.1038/Protex.2018.082 |
0.365 |
|
| 2017 |
Wapinski OL, Lee QY, Chen AC, Li R, Corces MR, Ang CE, Treutlein B, Xiang C, Baubet V, Suchy FP, Sankar V, Sim S, Quake SR, Dahmane N, Wernig M, et al. Rapid Chromatin Switch in the Direct Reprogramming of Fibroblasts to Neurons. Cell Reports. 20: 3236-3247. PMID 28954238 DOI: 10.1016/J.Celrep.2017.09.011 |
0.492 |
|
| 2017 |
Fantuzzo JA, De Filippis L, McGowan H, Yang N, Ng YH, Halikere A, Liu JJ, Hart RP, Wernig M, Zahn JD, Pang ZP. μNeurocircuitry: Establishing in vitro models of neurocircuits with human neurons. Technology. 5: 87-97. PMID 28781993 DOI: 10.1142/S2339547817500054 |
0.307 |
|
| 2017 |
Chanda S, Hale WD, Zhang B, Wernig M, Südhof TC. Unique vs. Redundant Functions of Neuroligin Genes in Shaping Excitatory and Inhibitory Synapse Properties. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 28607166 DOI: 10.1523/Jneurosci.0125-17.2017 |
0.334 |
|
| 2017 |
Mall M, Wernig M. The novel tool of cell reprogramming for applications in molecular medicine. Journal of Molecular Medicine (Berlin, Germany). PMID 28597071 DOI: 10.1007/S00109-017-1550-4 |
0.48 |
|
| 2017 |
Yang N, Chanda S, Marro S, Ng YH, Janas JA, Haag D, Ang CE, Tang Y, Flores Q, Mall M, Wapinski O, Li M, Ahlenius H, Rubenstein JL, Chang HY, ... ... Wernig M, et al. Generation of pure GABAergic neurons by transcription factor programming. Nature Methods. PMID 28504679 DOI: 10.1038/Nmeth.4291 |
0.782 |
|
| 2017 |
di Val Cervo PR, Romanov RA, Spigolon G, Masini D, Martín-Montañez E, Toledo EM, La Manno G, Feyder M, Pifl C, Ng YH, Sánchez SP, Linnarsson S, Wernig M, Harkany T, Fisone G, et al. Induction of functional dopamine neurons from human astrocytes in vitro and mouse astrocytes in a Parkinson's disease model. Nature Biotechnology. PMID 28398344 DOI: 10.1038/Nbt.3835 |
0.434 |
|
| 2017 |
Mall M, Kareta MS, Chanda S, Ahlenius H, Perotti N, Zhou B, Grieder SD, Ge X, Drake S, Euong Ang C, Walker BM, Vierbuchen T, Fuentes DR, Brennecke P, Nitta KR, ... ... Wernig M, et al. Myt1l safeguards neuronal identity by actively repressing many non-neuronal fates. Nature. PMID 28379941 DOI: 10.1038/Nature21722 |
0.459 |
|
| 2017 |
Chuang W, Sharma A, Shukla P, Li G, Mall M, Rajarajan K, Abilez OJ, Hamaguchi R, Wu JC, Wernig M, Wu SM. Partial Reprogramming of Pluripotent Stem Cell-Derived Cardiomyocytes into Neurons. Scientific Reports. 7: 44840. PMID 28327614 DOI: 10.1038/Srep44840 |
0.469 |
|
| 2017 |
Huang YA, Zhou B, Wernig M, Südhof TC. ApoE2, ApoE3, and ApoE4 Differentially Stimulate APP Transcription and Aβ Secretion. Cell. PMID 28111074 DOI: 10.1016/J.Cell.2016.12.044 |
0.339 |
|
| 2016 |
Chao MP, Gentles AJ, Chatterjee S, Lan F, Reinisch A, Corces MR, Xavy S, Shen J, Haag D, Chanda S, Sinha R, Morganti RM, Nishimura T, Ameen M, Wu H, ... Wernig M, et al. Human AML-iPSCs Reacquire Leukemic Properties after Differentiation and Model Clonal Variation of Disease. Cell Stem Cell. PMID 28089908 DOI: 10.1016/J.Stem.2016.11.018 |
0.462 |
|
| 2016 |
Osorio MJ, Rowitch DH, Tesar P, Wernig M, Windrem MS, Goldman SA. Concise Review: Stem Cell-Based Treatment of Pelizaeus-Merzbacher Disease. Stem Cells (Dayton, Ohio). PMID 27882623 DOI: 10.1002/Stem.2530 |
0.457 |
|
| 2016 |
Ahlenius H, Chanda S, Webb AE, Yousif I, Karmazin J, Prusiner SB, Brunet A, Südhof TC, Wernig M. FoxO3 regulates neuronal reprogramming of cells from postnatal and aging mice. Proceedings of the National Academy of Sciences of the United States of America. 113: 8514-9. PMID 27402759 DOI: 10.1073/Pnas.1607079113 |
0.45 |
|
| 2016 |
Treutlein B, Lee QY, Camp JG, Mall M, Koh W, Shariati SA, Sim S, Neff NF, Skotheim JM, Wernig M, Quake SR. Dissecting direct reprogramming from fibroblast to neuron using single-cell RNA-seq. Nature. PMID 27281220 DOI: 10.1038/Nature18323 |
0.52 |
|
| 2016 |
Patzke C, Acuna C, Giam LR, Wernig M, Südhof TC. Conditional deletion of L1CAM in human neurons impairs both axonal and dendritic arborization and action potential generation. The Journal of Experimental Medicine. 213: 499-515. PMID 27001749 DOI: 10.1084/Jem.20150951 |
0.419 |
|
| 2016 |
Carlson AL, Bennett NK, Francis NL, Halikere A, Clarke S, Moore JC, Hart RP, Paradiso K, Wernig M, Kohn J, Pang ZP, Moghe PV. Generation and transplantation of reprogrammed human neurons in the brain using 3D microtopographic scaffolds. Nature Communications. 7: 10862. PMID 26983594 DOI: 10.1038/Ncomms10862 |
0.444 |
|
| 2016 |
Yi F, Danko T, Botelho SC, Patzke C, Pak C, Wernig M, Südhof TC. Autism-associated SHANK3 haploinsufficiency causes Ih channelopathy in human neurons. Science (New York, N.Y.). 352: aaf2669. PMID 26966193 DOI: 10.1126/Science.Aaf2669 |
0.319 |
|
| 2016 |
Chao MP, Andrew G, Susmita C, Reinisch A, Corces MR, Shen J, Rachel M, Singha R, Haag D, Wernig M, Wu J, Majeti R. Pluripotent Reprogramming of Human AML Resets Leukemic Behavior and Models Therapeutic Targeting of Subclones Blood. 128: 575-575. DOI: 10.1182/Blood.V128.22.575.575 |
0.485 |
|
| 2016 |
Kareta MS, O'Brien M, Wernig M, Sage J. Abstract PR06: Sox2 functions as a critical oncogene in Rb loss initiated tumors Molecular Cancer Research. 14. DOI: 10.1158/1557-3125.Cellcycle16-Pr06 |
0.303 |
|
| 2015 |
Chen G, Wernig M, Berninger B, Nakafuku M, Parmar M, Zhang CL. In Vivo Reprogramming for Brain and Spinal Cord Repair(1,2,3). Eneuro. 2. PMID 26730402 DOI: 10.1523/ENEURO.0106-15.2015 |
0.327 |
|
| 2015 |
De Los Angeles A, Ferrari F, Xi R, Fujiwara Y, Benvenisty N, Deng H, Hochedlinger K, Jaenisch R, Lee S, Leitch HG, Lensch MW, Lujan E, Pei D, Rossant J, Wernig M, et al. Corrigendum: Hallmarks of pluripotency. Nature. PMID 26675727 DOI: 10.1038/Nature16470 |
0.554 |
|
| 2015 |
De Los Angeles A, Ferrari F, Fujiwara Y, Mathieu R, Lee S, Lee S, Tu HC, Ross S, Chou S, Nguyen M, Wu Z, Theunissen TW, Powell BE, Imsoonthornruksa S, Chen J, ... ... Wernig M, et al. Corrigendum: Failure to replicate the STAP cell phenomenon. Nature. PMID 26675720 DOI: 10.1038/Nature16479 |
0.491 |
|
| 2015 |
Cheloufi S, Elling U, Hopfgartner B, Jung YL, Murn J, Ninova M, Hubmann M, Badeaux AI, Euong Ang C, Tenen D, Wesche DJ, Abazova N, Hogue M, Tasdemir N, Brumbaugh J, ... ... Wernig M, et al. The histone chaperone CAF-1 safeguards somatic cell identity. Nature. 528: 218-224. PMID 26659182 DOI: 10.1038/Nature15749 |
0.511 |
|
| 2015 |
Kareta MS, Sage J, Wernig M. Crosstalk between stem cell and cell cycle machineries. Current Opinion in Cell Biology. 37: 68-74. PMID 26520682 DOI: 10.1016/J.Ceb.2015.10.001 |
0.495 |
|
| 2015 |
Tanabe K, Haag D, Wernig M. Direct somatic lineage conversion. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 370. PMID 26416679 DOI: 10.1098/Rstb.2014.0368 |
0.52 |
|
| 2015 |
De Los Angeles A, Ferrari F, Fujiwara Y, Mathieu R, Lee S, Lee S, Tu HC, Ross S, Chou S, Nguyen M, Wu Z, Theunissen TW, Powell BE, Imsoonthornruksa S, Chen J, ... ... Wernig M, et al. Failure to replicate the STAP cell phenomenon. Nature. 525: E6-9. PMID 26399835 DOI: 10.1038/Nature15513 |
0.491 |
|
| 2015 |
De Los Angeles A, Ferrari F, Xi R, Fujiwara Y, Benvenisty N, Deng H, Hochedlinger K, Jaenisch R, Lee S, Leitch HG, Lensch MW, Lujan E, Pei D, Rossant J, Wernig M, et al. Hallmarks of pluripotency. Nature. 525: 469-78. PMID 26399828 DOI: 10.1038/Nature15515 |
0.609 |
|
| 2015 |
Patzke C, Han Y, Covy J, Yi F, Maxeiner S, Wernig M, Südhof TC. Analysis of conditional heterozygous STXBP1 mutations in human neurons. The Journal of Clinical Investigation. 125: 3560-71. PMID 26280581 DOI: 10.1172/Jci78612 |
0.42 |
|
| 2015 |
Pak C, Danko T, Zhang Y, Aoto J, Anderson G, Maxeiner S, Yi F, Wernig M, Südhof TC. Human Neuropsychiatric Disease Modeling using Conditional Deletion Reveals Synaptic Transmission Defects Caused by Heterozygous Mutations in NRXN1. Cell Stem Cell. 17: 316-28. PMID 26279266 DOI: 10.1016/J.Stem.2015.07.017 |
0.365 |
|
| 2015 |
Lujan E, Zunder ER, Ng YH, Goronzy IN, Nolan GP, Wernig M. Early reprogramming regulators identified by prospective isolation and mass cytometry. Nature. 521: 352-6. PMID 25830878 DOI: 10.1038/Nature14274 |
0.492 |
|
| 2015 |
Zunder ER, Lujan E, Goltsev Y, Wernig M, Nolan GP. A continuous molecular roadmap to iPSC reprogramming through progression analysis of single-cell mass cytometry. Cell Stem Cell. 16: 323-37. PMID 25748935 DOI: 10.1016/J.Stem.2015.01.015 |
0.348 |
|
| 2015 |
Kareta MS, Gorges LL, Hafeez S, Benayoun BA, Marro S, Zmoos AF, Cecchini MJ, Spacek D, Batista LF, O'Brien M, Ng YH, Ang CE, Vaka D, Artandi SE, Dick FA, ... ... Wernig M, et al. Inhibition of pluripotency networks by the Rb tumor suppressor restricts reprogramming and tumorigenesis. Cell Stem Cell. 16: 39-50. PMID 25467916 DOI: 10.1016/J.Stem.2014.10.019 |
0.764 |
|
| 2014 |
Batista PJ, Molinie B, Wang J, Qu K, Zhang J, Li L, Bouley DM, Lujan E, Haddad B, Daneshvar K, Carter AC, Flynn RA, Zhou C, Lim KS, Dedon P, ... Wernig M, et al. m(6)A RNA modification controls cell fate transition in mammalian embryonic stem cells. Cell Stem Cell. 15: 707-19. PMID 25456834 DOI: 10.1016/J.Stem.2014.09.019 |
0.414 |
|
| 2014 |
Sebastiano V, Zhen HH, Haddad B, Derafshi BH, Bashkirova E, Melo SP, Wang P, Leung TL, Siprashvili Z, Tichy A, Li J, Ameen M, Hawkins J, Lee S, Li L, ... ... Wernig M, et al. Human COL7A1-corrected induced pluripotent stem cells for the treatment of recessive dystrophic epidermolysis bullosa. Science Translational Medicine. 6: 264ra163. PMID 25429056 DOI: 10.1126/Scitranslmed.3009540 |
0.462 |
|
| 2014 |
Chanda S, Ang CE, Davila J, Pak C, Mall M, Lee QY, Ahlenius H, Jung SW, Südhof TC, Wernig M. Generation of induced neuronal cells by the single reprogramming factor ASCL1. Stem Cell Reports. 3: 282-96. PMID 25254342 DOI: 10.1016/J.Stemcr.2014.05.020 |
0.528 |
|
| 2014 |
Ang CE, Wernig M. Induced neuronal reprogramming. The Journal of Comparative Neurology. 522: 2877-86. PMID 24771471 DOI: 10.1002/Cne.23620 |
0.534 |
|
| 2014 |
Cho A, Tang Y, Davila J, Deng S, Chen L, Miller E, Wernig M, Graef IA. Calcineurin signaling regulates neural induction through antagonizing the BMP pathway. Neuron. 82: 109-24. PMID 24698271 DOI: 10.1016/J.Neuron.2014.02.015 |
0.315 |
|
| 2014 |
Sebastiano V, Zhen HH, Haddad B, Bashkirova E, Melo SP, Wang P, Leung TL, Siprashvili Z, Tichy A, Li J, Ameen M, Hawkins J, Lee S, Li L, Schwertschkow A, ... ... Wernig M, et al. Erratum: Human COL7A1-corrected induced pluripotent stem cells for the treatment of recessive dystrophic epidermolysis bullosa (Science Translational Medicine (2014) 6 (267er8)) Science Translational Medicine. 6. DOI: 10.1126/Scitranslmed.Aaa4871 |
0.411 |
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| 2013 |
Yang N, Wernig M. Harnessing the stem cell potential: a case for neural stem cell therapy. Nature Medicine. 19: 1580-1. PMID 24309657 DOI: 10.1038/Nm.3425 |
0.439 |
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| 2013 |
Wapinski OL, Vierbuchen T, Qu K, Lee QY, Chanda S, Fuentes DR, Giresi PG, Ng YH, Marro S, Neff NF, Drechsel D, Martynoga B, Castro DS, Webb AE, Südhof TC, ... ... Wernig M, et al. Hierarchical mechanisms for direct reprogramming of fibroblasts to neurons. Cell. 155: 621-35. PMID 24243019 DOI: 10.1016/J.Cell.2013.09.028 |
0.791 |
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| 2013 |
Chanda S, Marro S, Wernig M, Südhof TC. Neurons generated by direct conversion of fibroblasts reproduce synaptic phenotype caused by autism-associated neuroligin-3 mutation. Proceedings of the National Academy of Sciences of the United States of America. 110: 16622-7. PMID 24046374 DOI: 10.1073/Pnas.1316240110 |
0.766 |
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| 2013 |
Webb AE, Pollina EA, Vierbuchen T, Urbán N, Ucar D, Leeman DS, Martynoga B, Sewak M, Rando TA, Guillemot F, Wernig M, Brunet A. FOXO3 shares common targets with ASCL1 genome-wide and inhibits ASCL1-dependent neurogenesis. Cell Reports. 4: 477-91. PMID 23891001 DOI: 10.1016/J.Celrep.2013.06.035 |
0.486 |
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| 2013 |
Zhang Y, Pak C, Han Y, Ahlenius H, Zhang Z, Chanda S, Marro S, Patzke C, Acuna C, Covy J, Xu W, Yang N, Danko T, Chen L, Wernig M, et al. Rapid single-step induction of functional neurons from human pluripotent stem cells. Neuron. 78: 785-98. PMID 23764284 DOI: 10.1016/J.Neuron.2013.05.029 |
0.804 |
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| 2013 |
Yang N, Zuchero JB, Ahlenius H, Marro S, Ng YH, Vierbuchen T, Hawkins JS, Geissler R, Barres BA, Wernig M. Generation of oligodendroglial cells by direct lineage conversion. Nature Biotechnology. 31: 434-9. PMID 23584610 DOI: 10.1038/Nbt.2564 |
0.776 |
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| 2013 |
Davila J, Chanda S, Ang CE, Südhof TC, Wernig M. Acute reduction in oxygen tension enhances the induction of neurons from human fibroblasts. Journal of Neuroscience Methods. 216: 104-9. PMID 23562599 DOI: 10.1016/J.Jneumeth.2013.03.020 |
0.498 |
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| 2013 |
Lujan E, Wernig M. An indirect approach to generating specific human cell types. Nature Methods. 10: 44-5. PMID 23269377 DOI: 10.1038/Nmeth.2325 |
0.443 |
|
| 2012 |
Vierbuchen T, Wernig M. Molecular roadblocks for cellular reprogramming. Molecular Cell. 47: 827-38. PMID 23020854 DOI: 10.1016/J.Molcel.2012.09.008 |
0.548 |
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| 2012 |
Lujan E, Wernig M. The many roads to Rome: induction of neural precursor cells from fibroblasts. Current Opinion in Genetics & Development. 22: 517-22. PMID 22868177 DOI: 10.1016/J.Gde.2012.07.002 |
0.554 |
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| 2012 |
Lujan E, Chanda S, Ahlenius H, Südhof TC, Wernig M. Direct conversion of mouse fibroblasts to self-renewing, tripotent neural precursor cells. Proceedings of the National Academy of Sciences of the United States of America. 109: 2527-32. PMID 22308465 DOI: 10.1073/Pnas.1121003109 |
0.553 |
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| 2012 |
Wernig M. ISDN2012_0291: Neural cells reprogrammed from non‐ectodermal cells International Journal of Developmental Neuroscience. 30: 639-639. DOI: 10.1016/J.Ijdevneu.2012.10.103 |
0.451 |
|
| 2011 |
Citri A, Pang ZP, Südhof TC, Wernig M, Malenka RC. Comprehensive qPCR profiling of gene expression in single neuronal cells. Nature Protocols. 7: 118-27. PMID 22193304 DOI: 10.1038/Nprot.2011.430 |
0.496 |
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| 2011 |
Yang N, Ng YH, Pang ZP, Südhof TC, Wernig M. Induced neuronal cells: how to make and define a neuron. Cell Stem Cell. 9: 517-25. PMID 22136927 DOI: 10.1016/J.Stem.2011.11.015 |
0.494 |
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| 2011 |
Ming GL, Brüstle O, Muotri A, Studer L, Wernig M, Christian KM. Cellular reprogramming: recent advances in modeling neurological diseases. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 16070-5. PMID 22072658 DOI: 10.1523/Jneurosci.4218-11.2011 |
0.374 |
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| 2011 |
Vierbuchen T, Wernig M. Direct lineage conversions: unnatural but useful? Nature Biotechnology. 29: 892-907. PMID 21997635 DOI: 10.1038/Nbt.1946 |
0.51 |
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| 2011 |
Marro S, Pang ZP, Yang N, Tsai MC, Qu K, Chang HY, Südhof TC, Wernig M. Direct lineage conversion of terminally differentiated hepatocytes to functional neurons. Cell Stem Cell. 9: 374-82. PMID 21962918 DOI: 10.1016/J.Stem.2011.09.002 |
0.811 |
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| 2011 |
Sebastiano V, Maeder ML, Angstman JF, Haddad B, Khayter C, Yeo DT, Goodwin MJ, Hawkins JS, Ramirez CL, Batista LF, Artandi SE, Wernig M, Joung JK. In situ genetic correction of the sickle cell anemia mutation in human induced pluripotent stem cells using engineered zinc finger nucleases. Stem Cells (Dayton, Ohio). 29: 1717-26. PMID 21898685 DOI: 10.1002/Stem.718 |
0.479 |
|
| 2011 |
Pang ZP, Yang N, Vierbuchen T, Ostermeier A, Fuentes DR, Yang TQ, Citri A, Sebastiano V, Marro S, Südhof TC, Wernig M. Induction of human neuronal cells by defined transcription factors. Nature. 476: 220-3. PMID 21617644 DOI: 10.1038/Nature10202 |
0.806 |
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| 2011 |
Batista LF, Pech MF, Zhong FL, Nguyen HN, Xie KT, Zaug AJ, Crary SM, Choi J, Sebastiano V, Cherry A, Giri N, Wernig M, Alter BP, Cech TR, Savage SA, et al. Telomere shortening and loss of self-renewal in dyskeratosis congenita induced pluripotent stem cells. Nature. 474: 399-402. PMID 21602826 DOI: 10.1038/Nature10084 |
0.466 |
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| 2010 |
Elefanty AG, Blelloch R, Passegué E, Wernig M, Mummery CL. On the streets of San Francisco: highlights from the ISSCR Annual Meeting 2010. Cell Stem Cell. 7: 443-50. PMID 20887950 DOI: 10.1016/J.Stem.2010.09.002 |
0.356 |
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| 2010 |
Xi J, Khalil M, Shishechian N, Hannes T, Pfannkuche K, Liang H, Fatima A, Haustein M, Suhr F, Bloch W, Reppel M, Sarić T, Wernig M, Jänisch R, Brockmeier K, et al. Comparison of contractile behavior of native murine ventricular tissue and cardiomyocytes derived from embryonic or induced pluripotent stem cells. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 24: 2739-51. PMID 20371616 DOI: 10.1096/Fj.09-145177 |
0.359 |
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| 2010 |
Carette JE, Pruszak J, Varadarajan M, Blomen VA, Gokhale S, Camargo FD, Wernig M, Jaenisch R, Brummelkamp TR. Generation of iPSCs from cultured human malignant cells. Blood. 115: 4039-42. PMID 20233975 DOI: 10.1182/Blood-2009-07-231845 |
0.644 |
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| 2010 |
Vierbuchen T, Ostermeier A, Pang ZP, Kokubu Y, Südhof TC, Wernig M. Direct conversion of fibroblasts to functional neurons by defined factors. Nature. 463: 1035-41. PMID 20107439 DOI: 10.1038/Nature08797 |
0.519 |
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| 2009 |
Kuzmenkin A, Liang H, Xu G, Pfannkuche K, Eichhorn H, Fatima A, Luo H, Saric T, Wernig M, Jaenisch R, Hescheler J. Functional characterization of cardiomyocytes derived from murine induced pluripotent stem cells in vitro. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 23: 4168-80. PMID 19703934 DOI: 10.1096/Fj.08-128546 |
0.605 |
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| 2009 |
Pfannkuche K, Liang H, Hannes T, Xi J, Fatima A, Nguemo F, Matzkies M, Wernig M, Jaenisch R, Pillekamp F, Halbach M, Schunkert H, Sarić T, Hescheler J, Reppel M. Cardiac myocytes derived from murine reprogrammed fibroblasts: intact hormonal regulation, cardiac ion channel expression and development of contractility. Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology. 24: 73-86. PMID 19590195 DOI: 10.1159/000227815 |
0.562 |
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| 2008 |
Marson A, Levine SS, Cole MF, Frampton GM, Brambrink T, Johnstone S, Guenther MG, Johnston WK, Wernig M, Newman J, Calabrese JM, Dennis LM, Volkert TL, Gupta S, Love J, et al. Connecting microRNA genes to the core transcriptional regulatory circuitry of embryonic stem cells. Cell. 134: 521-33. PMID 18692474 DOI: 10.1016/J.Cell.2008.07.020 |
0.696 |
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| 2008 |
Meissner A, Mikkelsen TS, Gu H, Wernig M, Hanna J, Sivachenko A, Zhang X, Bernstein BE, Nusbaum C, Jaffe DB, Gnirke A, Jaenisch R, Lander ES. Genome-scale DNA methylation maps of pluripotent and differentiated cells. Nature. 454: 766-70. PMID 18600261 DOI: 10.1038/Nature07107 |
0.542 |
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| 2008 |
Wernig M, Lengner CJ, Hanna J, Lodato MA, Steine E, Foreman R, Staerk J, Markoulaki S, Jaenisch R. A drug-inducible transgenic system for direct reprogramming of multiple somatic cell types. Nature Biotechnology. 26: 916-24. PMID 18594521 DOI: 10.1038/Nbt1483 |
0.787 |
|
| 2008 |
Mikkelsen TS, Hanna J, Zhang X, Ku M, Wernig M, Schorderet P, Bernstein BE, Jaenisch R, Lander ES, Meissner A. Dissecting direct reprogramming through integrative genomic analysis. Nature. 454: 49-55. PMID 18509334 DOI: 10.1038/Nature07056 |
0.621 |
|
| 2008 |
Hanna J, Markoulaki S, Schorderet P, Carey BW, Beard C, Wernig M, Creyghton MP, Steine EJ, Cassady JP, Foreman R, Lengner CJ, Dausman JA, Jaenisch R. Direct reprogramming of terminally differentiated mature B lymphocytes to pluripotency. Cell. 133: 250-64. PMID 18423197 DOI: 10.1016/J.Cell.2008.03.028 |
0.584 |
|
| 2008 |
Wernig M, Zhao JP, Pruszak J, Hedlund E, Fu D, Soldner F, Broccoli V, Constantine-Paton M, Isacson O, Jaenisch R. Neurons derived from reprogrammed fibroblasts functionally integrate into the fetal brain and improve symptoms of rats with Parkinson's disease. Proceedings of the National Academy of Sciences of the United States of America. 105: 5856-61. PMID 18391196 DOI: 10.1073/Pnas.0801677105 |
0.636 |
|
| 2008 |
Brambrink T, Foreman R, Welstead GG, Lengner CJ, Wernig M, Suh H, Jaenisch R. Sequential expression of pluripotency markers during direct reprogramming of mouse somatic cells. Cell Stem Cell. 2: 151-9. PMID 18371436 DOI: 10.1016/J.Stem.2008.01.004 |
0.638 |
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| 2008 |
Wernig M, Meissner A, Cassady JP, Jaenisch R. c-Myc is dispensable for direct reprogramming of mouse fibroblasts. Cell Stem Cell. 2: 10-2. PMID 18371415 DOI: 10.1016/J.Stem.2007.12.001 |
0.533 |
|
| 2008 |
Mikkelsen TS, Hanna J, Zhang X, Ku M, Wernig M, Schorderet P, Bernstein BE, Jaenisch R, Lander ES, Meissner A. Dissecting direct reprogramming through integrative genomic analysis (Nature (2008) 454, (49-55)) Nature. 454: 794. DOI: 10.1038/Nature07196 |
0.456 |
|
| 2008 |
Hanna J, Markoulaki S, Schorderet P, Carey BW, Beard C, Wernig M, Creyghton MP, Steine EJ, Cassady JP, Foreman R, Lengner CJ, Dausman JA, Jaenisch R. Direct Reprogramming of Terminally Differentiated Mature B Lymphocytes to Pluripotency (DOI:10.1016/j.cell.2008.03.028) Cell. 134: 365. DOI: 10.1016/j.cell.2008.07.013 |
0.492 |
|
| 2007 |
Hanna J, Wernig M, Markoulaki S, Sun CW, Meissner A, Cassady JP, Beard C, Brambrink T, Wu LC, Townes TM, Jaenisch R. Treatment of sickle cell anemia mouse model with iPS cells generated from autologous skin. Science (New York, N.Y.). 318: 1920-3. PMID 18063756 DOI: 10.1126/Science.1152092 |
0.644 |
|
| 2007 |
Meissner A, Wernig M, Jaenisch R. Direct reprogramming of genetically unmodified fibroblasts into pluripotent stem cells. Nature Biotechnology. 25: 1177-81. PMID 17724450 DOI: 10.1038/Nbt1335 |
0.624 |
|
| 2007 |
Mikkelsen TS, Ku M, Jaffe DB, Issac B, Lieberman E, Giannoukos G, Alvarez P, Brockman W, Kim TK, Koche RP, Lee W, Mendenhall E, O'Donovan A, Presser A, Russ C, ... ... Wernig M, et al. Genome-wide maps of chromatin state in pluripotent and lineage-committed cells. Nature. 448: 553-60. PMID 17603471 DOI: 10.1038/Nature06008 |
0.579 |
|
| 2007 |
Wernig M, Meissner A, Foreman R, Brambrink T, Ku M, Hochedlinger K, Bernstein BE, Jaenisch R. In vitro reprogramming of fibroblasts into a pluripotent ES-cell-like state. Nature. 448: 318-24. PMID 17554336 DOI: 10.1038/Nature05944 |
0.638 |
|
| 2006 |
Bernstein BE, Mikkelsen TS, Xie X, Kamal M, Huebert DJ, Cuff J, Fry B, Meissner A, Wernig M, Plath K, Jaenisch R, Wagschal A, Feil R, Schreiber SL, Lander ES. A bivalent chromatin structure marks key developmental genes in embryonic stem cells. Cell. 125: 315-26. PMID 16630819 DOI: 10.1016/J.Cell.2006.02.041 |
0.702 |
|
| 2006 |
Boyer LA, Plath K, Zeitlinger J, Brambrink T, Medeiros LA, Lee TI, Levine SS, Wernig M, Tajonar A, Ray MK, Bell GW, Otte AP, Vidal M, Gifford DK, Young RA, et al. Polycomb complexes repress developmental regulators in murine embryonic stem cells. Nature. 441: 349-53. PMID 16625203 DOI: 10.1038/Nature04733 |
0.811 |
|
| 2004 |
Wernig M, Benninger F, Schmandt T, Rade M, Tucker KL, Büssow H, Beck H, Brüstle O. Functional integration of embryonic stem cell-derived neurons in vivo. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 5258-68. PMID 15175396 DOI: 10.1523/Jneurosci.0428-04.200 |
0.517 |
|
| 2003 |
Benninger F, Beck H, Wernig M, Tucker KL, Brüstle O, Scheffler B. Functional integration of embryonic stem cell-derived neurons in hippocampal slice cultures. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 7075-83. PMID 12904468 DOI: 10.1523/Jneurosci.23-18-07075.2003 |
0.47 |
|
| 2003 |
Steffel J, Wernig M, Knauf U, Kumar S, Wiestler OD, Wernig A, Brüstle O. Migration and differentiation of myogenic precursors following transplantation into the developing rat brain. Stem Cells (Dayton, Ohio). 21: 181-9. PMID 12634414 DOI: 10.1634/Stemcells.21-2-181 |
0.415 |
|
| 2002 |
Wernig M, Tucker KL, Gornik V, Schneiders A, Buschwald R, Wiestler OD, Barde YA, Brüstle O. Tau EGFP embryonic stem cells: an efficient tool for neuronal lineage selection and transplantation. Journal of Neuroscience Research. 69: 918-24. PMID 12205684 DOI: 10.1002/Jnr.10395 |
0.526 |
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| 2002 |
Wernig M, Brüstle O. Fifty ways to make a neuron: shifts in stem cell hierarchy and their implications for neuropathology and CNS repair. Journal of Neuropathology and Experimental Neurology. 61: 101-10. PMID 11853015 DOI: 10.1093/Jnen/61.2.101 |
0.526 |
|
| 2001 |
Zhang SC, Wernig M, Duncan ID, Brüstle O, Thomson JA. In vitro differentiation of transplantable neural precursors from human embryonic stem cells. Nature Biotechnology. 19: 1129-33. PMID 11731781 DOI: 10.1038/Nbt1201-1129 |
0.485 |
|
| 2000 |
Faiella A, Wernig M, Consalez GG, Hostick U, Hofmann C, Hustert E, Boncinelli E, Balling R, Nadeau JH. A mouse model for valproate teratogenicity: parental effects, homeotic transformations, and altered HOX expression. Human Molecular Genetics. 9: 227-36. PMID 10607833 DOI: 10.1093/Hmg/9.2.227 |
0.335 |
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