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Pamela A. Silver - Publications

Affiliations: 
Systems Biology Harvard Medical School, Boston, MA, United States 
Area:
Intracellular Compartmentation
Website:
http://www.fas.harvard.edu/~biophys/Pamela_A_Silver.htm
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260 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Way JC, Burrill DR, Silver PA. Bioinspired Design of Artificial Signaling Systems. Biochemistry. PMID 35984429 DOI: 10.1021/acs.biochem.2c00368  0.772
2022 Ng TL, Olson EJ, Yoo TY, Weiss HS, Koide Y, Koch PD, Rollins NJ, Mach P, Meisinger T, Bricken T, Chang TZ, Molloy C, Zürcher J, Chang RL, Mitchison TJ, ... ... Silver PA, et al. High-Content Screening and Computational Prediction Reveal Viral Genes That Suppress the Innate Immune Response. Msystems. e0146621. PMID 35319251 DOI: 10.1128/msystems.01466-21  0.542
2022 Veling MT, Nguyen DT, Thadani NN, Oster ME, Rollins NJ, Brock KP, Bethel NP, Lim S, Baker D, Way JC, Marks DS, Chang RL, Silver PA. Natural and Designed Proteins Inspired by Extremotolerant Organisms Can Form Condensates and Attenuate Apoptosis in Human Cells. Acs Synthetic Biology. PMID 35176859 DOI: 10.1021/acssynbio.1c00572  0.538
2021 Lee J, Vernet A, Gruber NG, Kready KM, Burrill DR, Way JC, Silver PA. Rational engineering of an erythropoietin fusion protein to treat hypoxia. Protein Engineering, Design & Selection : Peds. 34. PMID 34725710 DOI: 10.1093/protein/gzab025  0.781
2021 Altenburg WJ, Rollins N, Silver PA, Giessen TW. Exploring targeting peptide-shell interactions in encapsulin nanocompartments. Scientific Reports. 11: 4951. PMID 33654191 DOI: 10.1038/s41598-021-84329-z  0.668
2020 Hsu BB, Plant IN, Lyon L, Anastassacos FM, Way JC, Silver PA. In situ reprogramming of gut bacteria by oral delivery. Nature Communications. 11: 5030. PMID 33024097 DOI: 10.1038/s41467-020-18614-2  0.726
2020 Stirling F, Silver PA. Controlling the Implementation of Transgenic Microbes: Are We Ready for What Synthetic Biology Has to Offer? Molecular Cell. 78: 614-623. PMID 32442504 DOI: 10.1016/J.Molcel.2020.03.034  0.32
2020 Hsu BB, Way JC, Silver PA. Stable Neutralization of a Virulence Factor in Bacteria Using Temperate Phage in the Mammalian Gut. Msystems. 5. PMID 31992629 DOI: 10.1128/mSystems.00013-20  0.729
2019 Tracey JC, Coronado M, Giessen TW, Lau MCY, Silver PA, Ward BB. The Discovery of Twenty-Eight New Encapsulin Sequences, Including Three in Anammox Bacteria. Scientific Reports. 9: 20122. PMID 31882935 DOI: 10.1038/S41598-019-56533-5  0.69
2019 Lee J, Vernet A, Redfield K, Lu S, Ghiran IC, Way JC, Silver PA. Rational Design of a Bifunctional AND-Gate Ligand to Modulate Cell-Cell Interactions. Acs Synthetic Biology. PMID 31834794 DOI: 10.1021/Acssynbio.9B00273  0.328
2019 Kim J, Zhou Y, Carlson PD, Teichmann M, Chaudhary S, Simmel FC, Silver PA, Collins JJ, Lucks JB, Yin P, Green AA. De novo-designed translation-repressing riboregulators for multi-input cellular logic. Nature Chemical Biology. PMID 31686032 DOI: 10.1038/S41589-019-0388-1  0.327
2019 Riglar DT, Richmond DL, Potvin-Trottier L, Verdegaal AA, Naydich AD, Bakshi S, Leoncini E, Lyon LG, Paulsson J, Silver PA. Bacterial variability in the mammalian gut captured by a single-cell synthetic oscillator. Nature Communications. 10: 4665. PMID 31604953 DOI: 10.1038/S41467-019-12638-Z  0.312
2019 Ziesack M, Gibson T, Oliver JKW, Shumaker AM, Hsu BB, Riglar DT, Giessen TW, DiBenedetto NV, Bry L, Way JC, Silver PA, Gerber GK. Engineered Interspecies Amino Acid Cross-Feeding Increases Population Evenness in a Synthetic Bacterial Consortium. Msystems. 4. PMID 31409662 DOI: 10.1128/mSystems.00352-19  0.778
2019 Giessen TW, Orlando BJ, Verdegaal AA, Chambers MG, Gardener J, Bell DC, Birrane G, Liao M, Silver PA. Large protein organelles form a new iron sequestration system with high storage capacity. Elife. 8. PMID 31282860 DOI: 10.2210/Pdb6N63/Pdb  0.658
2019 Naydich AD, Nangle SN, Bues JJ, Trivedi D, Nissar N, Inniss MC, Niederhuber MJ, Way JC, Silver PA, Riglar DT. Synthetic Gene Circuits Enable Systems-Level Biosensor Trigger Discovery at the Host-Microbe Interface. Msystems. 4. PMID 31186335 DOI: 10.1128/mSystems.00125-19  0.784
2019 Hsu BB, Gibson TE, Yeliseyev V, Liu Q, Lyon L, Bry L, Silver PA, Gerber GK. Dynamic Modulation of the Gut Microbiota and Metabolome by Bacteriophages in a Mouse Model. Cell Host & Microbe. PMID 31175044 DOI: 10.1016/J.Chom.2019.05.001  0.729
2019 Tscherner M, Giessen TW, Markey L, Kumamoto C, Silver PA. A synthetic system that senses Candida albicans and inhibits virulence factors. Acs Synthetic Biology. PMID 30608638 DOI: 10.1021/Acssynbio.8B00457  0.663
2018 Lau YH, Giessen TW, Altenburg WJ, Silver PA. Prokaryotic nanocompartments form synthetic organelles in a eukaryote. Nature Communications. 9: 1311. PMID 29615617 DOI: 10.1038/S41467-018-03768-X  0.72
2017 Green AA, Kim J, Ma D, Silver PA, Collins JJ, Yin P. Complex cellular logic computation using ribocomputing devices. Nature. PMID 28746304 DOI: 10.1038/Nature23271  0.322
2017 Riglar DT, Giessen TW, Baym M, Kerns SJ, Niederhuber MJ, Bronson RT, Kotula JW, Gerber GK, Way JC, Silver PA. Engineered bacteria can function in the mammalian gut long-term as live diagnostics of inflammation. Nature Biotechnology. PMID 28553941 DOI: 10.1038/Nbt.3879  0.672
2017 Giessen TW, Silver PA. Widespread distribution of encapsulin nanocompartments reveals functional diversity. Nature Microbiology. 2: 17029. PMID 28263314 DOI: 10.1038/Nmicrobiol.2017.29  0.714
2017 Giessen TW, Silver PA. Engineering carbon fixation with artificial protein organelles. Current Opinion in Biotechnology. 46: 42-50. PMID 28126670 DOI: 10.1016/J.Copbio.2017.01.004  0.675
2016 Brown DM, Chan YA, Desai PJ, Grzesik P, Oldfield LM, Vashee S, Way JC, Silver PA, Glass JI. Efficient size-independent chromosome delivery from yeast to cultured cell lines. Nucleic Acids Research. PMID 27980064 DOI: 10.1093/Nar/Gkw1252  0.303
2016 Liu X, Lopez PA, Giessen TW, Giles M, Way JC, Silver PA. Engineering Genetically-Encoded Mineralization and Magnetism via Directed Evolution. Scientific Reports. 6: 38019. PMID 27897245 DOI: 10.1038/Srep38019  0.671
2016 Giessen TW, Silver PA. A Catalytic Nanoreactor Based on in Vivo Encapsulation of Multiple Enzymes in an Engineered Protein Nanocompartment. Chembiochem : a European Journal of Chemical Biology. PMID 27504846 DOI: 10.1002/Cbic.201600431  0.697
2016 Myhrvold C, Polka JK, Silver PA. Synthetic Lipid-Containing Scaffolds Enhance Production by Colocalizing Enzymes. Acs Synthetic Biology. PMID 27487319 DOI: 10.1021/Acssynbio.6B00141  0.336
2016 Lee JW, Gyorgy A, Cameron DE, Pyenson N, Choi KR, Way JC, Silver PA, Del Vecchio D, Collins JJ. Creating Single-Copy Genetic Circuits. Molecular Cell. PMID 27425413 DOI: 10.1016/J.Molcel.2016.06.006  0.301
2016 Giessen TW, Silver PA. Converting a natural protein compartment into a nanofactory for the size-constrained synthesis of antimicrobial silver nanoparticles. Acs Synthetic Biology. PMID 27276075 DOI: 10.1021/Acssynbio.6B00117  0.661
2016 Polka JK, Hays SG, Silver PA. Building Spatial Synthetic Biology with Compartments, Scaffolds, and Communities. Cold Spring Harbor Perspectives in Biology. PMID 27270297 DOI: 10.1101/Cshperspect.A024018  0.334
2016 Burrill DR, Vernet A, Collins JJ, Silver PA, Way JC. Targeted erythropoietin selectively stimulates red blood cell expansion in vivo. Proceedings of the National Academy of Sciences of the United States of America. PMID 27114509 DOI: 10.1073/Pnas.1525388113  0.782
2016 MacKellar D, Lieber L, Norman JS, Bolger A, Tobin C, Murray JW, Oksaksin M, Chang RL, Ford TJ, Nguyen PQ, Woodward J, Permingeat HR, Joshi NS, Silver PA, Usadel B, et al. Streptomyces thermoautotrophicus does not fix nitrogen. Scientific Reports. 6: 20086. PMID 26833023 DOI: 10.1038/Srep20086  0.544
2015 Giessen TW, Silver PA. Encapsulation as a Strategy for the Design of Biological Compartmentalization. Journal of Molecular Biology. PMID 26403362 DOI: 10.1016/J.Jmb.2015.09.009  0.703
2015 Chen AH, Lubkowicz D, Yeong V, Chang RL, Silver PA. Transplantability of a circadian clock to a noncircadian organism. Science Advances. 1. PMID 26229984 DOI: 10.1126/Sciadv.1500358  0.586
2015 Ford TJ, Silver PA. Synthetic biology expands chemical control of microorganisms. Current Opinion in Chemical Biology. 28: 20-28. PMID 26056951 DOI: 10.1016/J.Cbpa.2015.05.012  0.309
2015 Myhrvold C, Silver PA. Using synthetic RNAs as scaffolds and regulators. Nature Structural & Molecular Biology. 22: 8-10. PMID 25565027 DOI: 10.1038/Nsmb.2944  0.322
2014 Robinson-Mosher A, Chen JH, Way J, Silver PA. Designing cell-targeted therapeutic proteins reveals the interplay between domain connectivity and cell binding. Biophysical Journal. 107: 2456-66. PMID 25418314 DOI: 10.1016/J.Bpj.2014.10.007  0.311
2014 Green AA, Silver PA, Collins JJ, Yin P. Toehold switches: de-novo-designed regulators of gene expression. Cell. 159: 925-39. PMID 25417166 DOI: 10.1016/J.Cell.2014.10.002  0.345
2014 Sachdeva G, Garg A, Godding D, Way JC, Silver PA. In vivo co-localization of enzymes on RNA scaffolds increases metabolic production in a geometrically dependent manner. Nucleic Acids Research. 42: 9493-503. PMID 25034694 DOI: 10.1093/Nar/Gku617  0.36
2014 Mattozzi MD, Voges MJ, Silver PA, Way JC. Transient gene expression in tobacco using Gibson assembly and the Gene Gun. Journal of Visualized Experiments : Jove. PMID 24796418 DOI: 10.3791/51234  0.38
2014 Way JC, Collins JJ, Keasling JD, Silver PA. Integrating biological redesign: where synthetic biology came from and where it needs to go. Cell. 157: 151-61. PMID 24679533 DOI: 10.1016/J.Cell.2014.02.039  0.319
2014 Weyn-Vanhentenryck SM, Mele A, Yan Q, Sun S, Farny N, Zhang Z, Xue C, Herre M, Silver PA, Zhang MQ, Krainer AR, Darnell RB, Zhang C. HITS-CLIP and integrative modeling define the Rbfox splicing-regulatory network linked to brain development and autism. Cell Reports. 6: 1139-52. PMID 24613350 DOI: 10.1016/J.Celrep.2014.02.005  0.779
2014 Lienert F, Lohmueller JJ, Garg A, Silver PA. Synthetic biology in mammalian cells: next generation research tools and therapeutics. Nature Reviews. Molecular Cell Biology. 15: 95-107. PMID 24434884 DOI: 10.1038/Nrm3738  0.75
2014 Torella JP, Boehm CR, Lienert F, Chen JH, Way JC, Silver PA. Rapid construction of insulated genetic circuits via synthetic sequence-guided isothermal assembly. Nucleic Acids Research. 42: 681-9. PMID 24078086 DOI: 10.1093/Nar/Gkt860  0.319
2013 Polka JK, Silver PA. Building synthetic cellular organization. Molecular Biology of the Cell. 24: 3585-7. PMID 24288075 DOI: 10.1091/Mbc.E13-03-0155  0.344
2013 Wintermute EH, Lieberman TD, Silver PA. An objective function exploiting suboptimal solutions in metabolic networks. Bmc Systems Biology. 7: 98. PMID 24088221 DOI: 10.1186/1752-0509-7-98  0.76
2013 Inniss MC, Silver PA. Building synthetic memory. Current Biology : Cb. 23: R812-6. PMID 24028965 DOI: 10.1016/J.Cub.2013.06.047  0.773
2013 Chen AH, Robinson-Mosher A, Savage DF, Silver PA, Polka JK. The bacterial carbon-fixing organelle is formed by shell envelopment of preassembled cargo. Plos One. 8: e76127. PMID 24023971 DOI: 10.1371/Journal.Pone.0076127  0.587
2013 Voges MJ, Silver PA, Way JC, Mattozzi MD. Targeting a heterologous protein to multiple plant organelles via rationally designed 5' mRNA tags. Journal of Biological Engineering. 7: 20. PMID 24011257 DOI: 10.1186/1754-1611-7-20  0.349
2013 Lienert F, Torella JP, Chen JH, Norsworthy M, Richardson RR, Silver PA. Two- and three-input TALE-based AND logic computation in embryonic stem cells. Nucleic Acids Research. 41: 9967-75. PMID 23982518 DOI: 10.1093/Nar/Gkt758  0.777
2013 Robinson-Mosher A, Shinar T, Silver PA, Way J. Dynamics simulations for engineering macromolecular interactions. Chaos (Woodbury, N.Y.). 23: 025110. PMID 23822508 DOI: 10.1063/1.4810915  0.364
2013 Selgrade DF, Lohmueller JJ, Lienert F, Silver PA. Protein scaffold-activated protein trans-splicing in mammalian cells. Journal of the American Chemical Society. 135: 7713-9. PMID 23621664 DOI: 10.1021/Ja401689B  0.749
2013 Wang Q, Moore MJ, Adelmant G, Marto JA, Silver PA. PQBP1, a factor linked to intellectual disability, affects alternative splicing associated with neurite outgrowth. Genes & Development. 27: 615-26. PMID 23512658 DOI: 10.1101/Gad.212308.112  0.357
2013 Mattozzi Md, Ziesack M, Voges MJ, Silver PA, Way JC. Expression of the sub-pathways of the Chloroflexus aurantiacus 3-hydroxypropionate carbon fixation bicycle in E. coli: Toward horizontal transfer of autotrophic growth. Metabolic Engineering. 16: 130-9. PMID 23376595 DOI: 10.1016/J.Ymben.2013.01.005  0.318
2012 Chen AH, Afonso B, Silver PA, Savage DF. Spatial and temporal organization of chromosome duplication and segregation in the cyanobacterium Synechococcus elongatus PCC 7942. Plos One. 7: e47837. PMID 23112856 DOI: 10.1371/Journal.Pone.0047837  0.771
2012 Delebecque CJ, Silver PA, Lindner AB. Designing and using RNA scaffolds to assemble proteins in vivo. Nature Protocols. 7: 1797-807. PMID 22955695 DOI: 10.1038/Nprot.2012.102  0.348
2012 Chen AH, Silver PA. Designing biological compartmentalization. Trends in Cell Biology. 22: 662-70. PMID 22841504 DOI: 10.1016/J.Tcb.2012.07.002  0.314
2012 Burrill DR, Inniss MC, Boyle PM, Silver PA. Synthetic memory circuits for tracking human cell fate. Genes & Development. 26: 1486-97. PMID 22751502 DOI: 10.1101/Gad.189035.112  0.774
2012 Chen AJ, Paik JH, Zhang H, Shukla SA, Mortensen R, Hu J, Ying H, Hu B, Hurt J, Farny N, Dong C, Xiao Y, Wang YA, Silver PA, Chin L, et al. STAR RNA-binding protein Quaking suppresses cancer via stabilization of specific miRNA. Genes & Development. 26: 1459-72. PMID 22751500 DOI: 10.1101/Gad.189001.112  0.783
2012 Boyle PM, Burrill DR, Inniss MC, Agapakis CM, Deardon A, Dewerd JG, Gedeon MA, Quinn JY, Paull ML, Raman AM, Theilmann MR, Wang L, Winn JC, Medvedik O, Schellenberg K, ... ... Silver PA, et al. A BioBrick compatible strategy for genetic modification of plants. Journal of Biological Engineering. 6: 8. PMID 22716313 DOI: 10.1186/1754-1611-6-8  0.759
2012 Agapakis CM, Boyle PM, Silver PA. Natural strategies for the spatial optimization of metabolism in synthetic biology. Nature Chemical Biology. 8: 527-35. PMID 22596204 DOI: 10.1038/Nchembio.975  0.754
2012 Garg A, Lohmueller JJ, Silver PA, Armel TZ. Engineering synthetic TAL effectors with orthogonal target sites. Nucleic Acids Research. 40: 7584-95. PMID 22581776 DOI: 10.1093/Nar/Gks404  0.741
2012 Adelmant G, Calkins AS, Garg BK, Card JD, Askenazi M, Miron A, Sobhian B, Zhang Y, Nakatani Y, Silver PA, Iglehart JD, Marto JA, Lazaro JB. DNA ends alter the molecular composition and localization of Ku multicomponent complexes. Molecular & Cellular Proteomics : McP. 11: 411-21. PMID 22535209 DOI: 10.1074/Mcp.M111.013581  0.336
2012 Haynes KA, Ceroni F, Flicker D, Younger A, Silver PA. A sensitive switch for visualizing natural gene silencing in single cells. Acs Synthetic Biology. 1: 99-106. PMID 22530199 DOI: 10.1021/Sb3000035  0.323
2012 Lohmueller JJ, Armel TZ, Silver PA. A tunable zinc finger-based framework for Boolean logic computation in mammalian cells. Nucleic Acids Research. 40: 5180-7. PMID 22323524 DOI: 10.1093/Nar/Gks142  0.744
2012 Bonacci W, Teng PK, Afonso B, Niederholtmeyer H, Grob P, Silver PA, Savage DF. Modularity of a carbon-fixing protein organelle. Proceedings of the National Academy of Sciences of the United States of America. 109: 478-83. PMID 22184212 DOI: 10.1073/Pnas.1108557109  0.804
2012 Silver PA. Abstract IA4: Designing biological systems to report on disease Cancer Research. 72. DOI: 10.1158/1538-7445.Csb12-Ia4  0.319
2012 Silver PA, Haynes K, Weiss R. Synthetic meets cell biology Molecular Biology of the Cell. 23: 967. DOI: 10.1091/Mbc.E11-12-0978  0.345
2012 Silver P. Designing Intracellular Organization for Optimization of Sustainability Biophysical Journal. 102. DOI: 10.1016/J.Bpj.2011.11.192  0.334
2011 Burrill DR, Boyle PM, Silver PA. A new approach to an old problem: synthetic biology tools for human disease and metabolism. Cold Spring Harbor Symposia On Quantitative Biology. 76: 145-54. PMID 22169233 DOI: 10.1101/Sqb.2011.76.010686  0.769
2011 Waks Z, Klein AM, Silver PA. Cell-to-cell variability of alternative RNA splicing. Molecular Systems Biology. 7: 506. PMID 21734645 DOI: 10.1038/Msb.2011.32  0.796
2011 Delebecque CJ, Lindner AB, Silver PA, Aldaye FA. Organization of intracellular reactions with rationally designed RNA assemblies. Science (New York, N.Y.). 333: 470-4. PMID 21700839 DOI: 10.1126/Science.1206938  0.768
2011 Burrill DR, Silver PA. Recording cellular experiences of DNA damage. Cell Cycle (Georgetown, Tex.). 10: 2410-1. PMID 21670599 DOI: 10.4161/Cc.10.15.16384  0.751
2011 Haynes KA, Silver PA. Synthetic reversal of epigenetic silencing. The Journal of Biological Chemistry. 286: 27176-82. PMID 21669865 DOI: 10.1074/Jbc.C111.229567  0.392
2011 Shih JD, Waks Z, Kedersha N, Silver PA. Visualization of single mRNAs reveals temporal association of proteins with microRNA-regulated mRNA. Nucleic Acids Research. 39: 7740-9. PMID 21653551 DOI: 10.1093/Nar/Gkr456  0.771
2011 Barstow B, Agapakis CM, Boyle PM, Grandl G, Silver PA, Wintermute EH. A synthetic system links FeFe-hydrogenases to essential E. coli sulfur metabolism. Journal of Biological Engineering. 5: 7. PMID 21615937 DOI: 10.1186/1754-1611-5-7  0.773
2011 Agapakis CM, Niederholtmeyer H, Noche RR, Lieberman TD, Megason SG, Way JC, Silver PA. Towards a synthetic chloroplast. Plos One. 6: e18877. PMID 21533097 DOI: 10.1371/Journal.Pone.0018877  0.762
2011 Senapedis WT, Kennedy CJ, Boyle PM, Silver PA. Whole genome siRNA cell-based screen links mitochondria to Akt signaling network through uncoupling of electron transport chain. Molecular Biology of the Cell. 22: 1791-805. PMID 21460183 DOI: 10.1091/Mbc.E10-10-0854  0.77
2011 Burrill DR, Silver PA. Synthetic circuit identifies subpopulations with sustained memory of DNA damage. Genes & Development. 25: 434-9. PMID 21363961 DOI: 10.1101/Gad.1994911  0.775
2010 Agapakis CM, Silver PA. Modular electron transfer circuits for synthetic biology: insulation of an engineered biohydrogen pathway. Bioengineered Bugs. 1: 413-8. PMID 21468209 DOI: 10.4161/Bbug.1.6.12462  0.756
2010 Waks Z, Silver PA. Nuclear origins of cell-to-cell variability. Cold Spring Harbor Symposia On Quantitative Biology. 75: 87-94. PMID 21447820 DOI: 10.1101/Sqb.2010.75.027  0.795
2010 Wintermute EH, Silver PA. Dynamics in the mixed microbial concourse. Genes & Development. 24: 2603-14. PMID 21123647 DOI: 10.1101/Gad.1985210  0.766
2010 Wang Q, Silver PA. Genome-wide RNAi screen discovers functional coupling of alternative splicing and cell cycle control to apoptosis regulation. Cell Cycle (Georgetown, Tex.). 9: 4419-21. PMID 21088477 DOI: 10.4161/Cc.9.22.14051  0.401
2010 Aldaye FA, Senapedis WT, Silver PA, Way JC. A structurally tunable DNA-based extracellular matrix. Journal of the American Chemical Society. 132: 14727-9. PMID 20925350 DOI: 10.1021/Ja105431H  0.791
2010 Wintermute EH, Silver PA. Emergent cooperation in microbial metabolism. Molecular Systems Biology. 6: 407. PMID 20823845 DOI: 10.1038/Msb.2010.66  0.768
2010 Moore MJ, Wang Q, Kennedy CJ, Silver PA. An alternative splicing network links cell-cycle control to apoptosis. Cell. 142: 625-36. PMID 20705336 DOI: 10.1016/J.Cell.2010.07.019  0.597
2010 Niederholtmeyer H, Wolfstädter BT, Savage DF, Silver PA, Way JC. Engineering cyanobacteria to synthesize and export hydrophilic products. Applied and Environmental Microbiology. 76: 3462-6. PMID 20363793 DOI: 10.1128/Aem.00202-10  0.593
2010 Savage DF, Afonso B, Chen AH, Silver PA. Spatially ordered dynamics of the bacterial carbon fixation machinery. Science (New York, N.Y.). 327: 1258-61. PMID 20203050 DOI: 10.1126/Science.1186090  0.774
2010 Agapakis CM, Ducat DC, Boyle PM, Wintermute EH, Way JC, Silver PA. Insulation of a synthetic hydrogen metabolism circuit in bacteria. Journal of Biological Engineering. 4: 3. PMID 20184755 DOI: 10.1186/1754-1611-4-3  0.79
2010 Afonso B, Silver PA, Ajo-Franklin CM. A synthetic circuit for selectively arresting daughter cells to create aging populations. Nucleic Acids Research. 38: 2727-35. PMID 20150416 DOI: 10.1093/Nar/Gkq075  0.729
2010 Burrill DR, Silver PA. Making cellular memories. Cell. 140: 13-8. PMID 20085698 DOI: 10.1016/J.Cell.2009.12.034  0.76
2010 Taylor ND, Way JC, Silver PA, Cironi P. Anti-glycophorin single-chain Fv fusion to low-affinity mutant erythropoietin improves red blood cell-lineage specificity. Protein Engineering, Design & Selection : Peds. 23: 251-60. PMID 20083493 DOI: 10.1093/Protein/Gzp085  0.3
2009 Silver P. Indirect immunofluorescence labeling in the yeast Saccharomyces cerevisiae. Cold Spring Harbor Protocols. 2009: pdb.prot5317. PMID 20150056 DOI: 10.1101/Pdb.Prot5317  0.397
2009 Haynes KA, Silver PA. Eukaryotic systems broaden the scope of synthetic biology. The Journal of Cell Biology. 187: 589-96. PMID 19948487 DOI: 10.1083/Jcb.200908138  0.335
2009 Farny NG, Kedersha NL, Silver PA. Metazoan stress granule assembly is mediated by P-eIF2alpha-dependent and -independent mechanisms. Rna (New York, N.Y.). 15: 1814-21. PMID 19661161 DOI: 10.1261/Rna.1684009  0.754
2009 Kennedy CJ, Boyle PM, Waks Z, Silver PA. Systems-level engineering of nonfermentative metabolism in yeast. Genetics. 183: 385-97. PMID 19564482 DOI: 10.1534/Genetics.109.105254  0.798
2009 Agapakis CM, Silver PA. Synthetic biology: exploring and exploiting genetic modularity through the design of novel biological networks. Molecular Biosystems. 5: 704-13. PMID 19562109 DOI: 10.1039/B901484E  0.759
2009 Hurt JA, Obar RA, Zhai B, Farny NG, Gygi SP, Silver PA. A conserved CCCH-type zinc finger protein regulates mRNA nuclear adenylation and export. The Journal of Cell Biology. 185: 265-77. PMID 19364924 DOI: 10.1083/Jcb.200811072  0.801
2009 Boyle PM, Silver PA. Harnessing nature's toolbox: regulatory elements for synthetic biology. Journal of the Royal Society, Interface / the Royal Society. 6: S535-46. PMID 19324675 DOI: 10.1098/Rsif.2008.0521.Focus  0.354
2009 Waks Z, Silver PA. Engineering a synthetic dual-organism system for hydrogen production. Applied and Environmental Microbiology. 75: 1867-75. PMID 19201964 DOI: 10.1128/Aem.02009-08  0.773
2009 Lee SI, Dudley AM, Drubin D, Silver PA, Krogan NJ, Pe'er D, Koller D. Learning a prior on regulatory potential from eQTL data. Plos Genetics. 5: e1000358. PMID 19180192 DOI: 10.1371/Journal.Pgen.1000358  0.345
2008 Hurt JA, Silver PA. mRNA nuclear export and human disease. Disease Models & Mechanisms. 1: 103-8. PMID 19048072 DOI: 10.1242/Dmm.000745  0.75
2008 Swinburne IA, Miguez DG, Landgraf D, Silver PA. Intron length increases oscillatory periods of gene expression in animal cells. Genes & Development. 22: 2342-6. PMID 18703678 DOI: 10.1101/Gad.1696108  0.751
2008 Swinburne IA, Silver PA. Intron delays and transcriptional timing during development. Developmental Cell. 14: 324-30. PMID 18331713 DOI: 10.1016/J.Devcel.2008.02.002  0.75
2008 Brown CR, Kennedy CJ, Delmar VA, Forbes DJ, Silver PA. Global histone acetylation induces functional genomic reorganization at mammalian nuclear pore complexes. Genes & Development. 22: 627-39. PMID 18316479 DOI: 10.1101/Gad.1632708  0.601
2008 Cironi P, Swinburne IA, Silver PA. Enhancement of cell type specificity by quantitative modulation of a chimeric ligand. The Journal of Biological Chemistry. 283: 8469-76. PMID 18230610 DOI: 10.1074/Jbc.M708502200  0.754
2008 Savage DF, Way J, Silver PA. Defossiling fuel: how synthetic biology can transform biofuel production. Acs Chemical Biology. 3: 13-6. PMID 18205286 DOI: 10.1021/Cb700259J  0.567
2008 Frietze S, Lupien M, Silver PA, Brown M. CARM1 regulates estrogen-stimulated breast cancer growth through up-regulation of E2F1. Cancer Research. 68: 301-6. PMID 18172323 DOI: 10.1158/0008-5472.Can-07-1983  0.631
2008 Farny NG, Hurt JA, Silver PA. Definition of global and transcript-specific mRNA export pathways in metazoans. Genes & Development. 22: 66-78. PMID 18086857 DOI: 10.1101/Gad.1616008  0.807
2008 Moore MJ, Silver PA. Global analysis of mRNA splicing. Rna (New York, N.Y.). 14: 197-203. PMID 18083834 DOI: 10.1261/Rna.868008  0.34
2008 Komili S, Silver PA. Coupling and coordination in gene expression processes: a systems biology view. Nature Reviews. Genetics. 9: 38-48. PMID 18071322 DOI: 10.1038/Nrg2223  0.805
2007 Komili S, Farny NG, Roth FP, Silver PA. Functional specificity among ribosomal proteins regulates gene expression. Cell. 131: 557-71. PMID 17981122 DOI: 10.1016/J.Cell.2007.08.037  0.814
2007 Ajo-Franklin CM, Drubin DA, Eskin JA, Gee EP, Landgraf D, Phillips I, Silver PA. Rational design of memory in eukaryotic cells. Genes & Development. 21: 2271-6. PMID 17875664 DOI: 10.1101/Gad.1586107  0.332
2007 McKee AE, Neretti N, Carvalho LE, Meyer CA, Fox EA, Brodsky AS, Silver PA. Exon expression profiling reveals stimulus-mediated exon use in neural cells. Genome Biology. 8: R159. PMID 17683528 DOI: 10.1186/Gb-2007-8-8-R159  0.703
2007 McKee AE, Silver PA. Systems perspectives on mRNA processing. Cell Research. 17: 581-90. PMID 17621309 DOI: 10.1038/Cr.2007.54  0.698
2007 Brown CR, Silver PA. Transcriptional regulation at the nuclear pore complex. Current Opinion in Genetics & Development. 17: 100-6. PMID 17317147 DOI: 10.1016/J.Gde.2007.02.005  0.397
2007 Arbiser JL, Kau T, Konar M, Narra K, Ramchandran R, Summers SA, Vlahos CJ, Ye K, Perry BN, Matter W, Fischl A, Cook J, Silver PA, Bain J, Cohen P, et al. Solenopsin, the alkaloidal component of the fire ant (Solenopsis invicta), is a naturally occurring inhibitor of phosphatidylinositol-3-kinase signaling and angiogenesis. Blood. 109: 560-5. PMID 16990598 DOI: 10.1182/Blood-2006-06-029934  0.778
2006 Damelin M, Silver P. Analysis of Protein Interactions In Vivo with Fluorescence Resonance Energy Transfer (FRET). Csh Protocols. 2006. PMID 22485962 DOI: 10.1101/Pdb.Prot4581  0.72
2006 Damelin M, Silver P. An Explanation of Symbols Used for Analysis of FRET Data. Csh Protocols. 2006. PMID 22485937 DOI: 10.1101/Pdb.Ip9  0.679
2006 Damelin M, Silver P. Equipment for In Vivo FRET Analysis. Csh Protocols. 2006. PMID 22485936 DOI: 10.1101/Pdb.Ip8  0.695
2006 Damelin M, Silver P. Experimental Design for In Vivo FRET Analysis. Csh Protocols. 2006. PMID 22485930 DOI: 10.1101/Pdb.Ip10  0.69
2006 Moore MJ, Schwartzfarb EM, Silver PA, Yu MC. Differential recruitment of the splicing machinery during transcription predicts genome-wide patterns of mRNA splicing. Molecular Cell. 24: 903-15. PMID 17189192 DOI: 10.1016/J.Molcel.2006.12.006  0.38
2006 Yu MC, Lamming DW, Eskin JA, Sinclair DA, Silver PA. The role of protein arginine methylation in the formation of silent chromatin. Genes & Development. 20: 3249-54. PMID 17158743 DOI: 10.1101/Gad.1495206  0.334
2006 Gama-Carvalho M, Barbosa-Morais NL, Brodsky AS, Silver PA, Carmo-Fonseca M. Genome-wide identification of functionally distinct subsets of cellular mRNAs associated with two nucleocytoplasmic-shuttling mammalian splicing factors. Genome Biology. 7: R113. PMID 17137510 DOI: 10.1186/Gb-2006-7-11-R113  0.395
2006 Tsankov AM, Brown CR, Yu MC, Win MZ, Silver PA, Casolari JM. Communication between levels of transcriptional control improves robustness and adaptivity. Molecular Systems Biology. 2: 65. PMID 17130867 DOI: 10.1038/Msb4100106  0.409
2006 Goffin L, Vodala S, Fraser C, Ryan J, Timms M, Meusburger S, Catimel B, Nice EC, Silver PA, Xiao CY, Jans DA, Gething MJ. The unfolded protein response transducer Ire1p contains a nuclear localization sequence recognized by multiple beta importins. Molecular Biology of the Cell. 17: 5309-23. PMID 17035634 DOI: 10.1091/Mbc.E06-04-0292  0.374
2006 Carroll JS, Meyer CA, Song J, Li W, Geistlinger TR, Eeckhoute J, Brodsky AS, Keeton EK, Fertuck KC, Hall GF, Wang Q, Bekiranov S, Sementchenko V, Fox EA, Silver PA, et al. Genome-wide analysis of estrogen receptor binding sites. Nature Genetics. 38: 1289-97. PMID 17013392 DOI: 10.1038/Ng1901  0.315
2006 Auld KL, Silver PA. Transcriptional regulation by the proteasome as a mechanism for cellular protein homeostasis. Cell Cycle (Georgetown, Tex.). 5: 1503-5. PMID 16861887 DOI: 10.4161/Cc.5.14.2979  0.817
2006 Auld KL, Hitchcock AL, Doherty HK, Frietze S, Huang LS, Silver PA. The conserved ATPase Get3/Arr4 modulates the activity of membrane-associated proteins in Saccharomyces cerevisiae. Genetics. 174: 215-27. PMID 16816426 DOI: 10.1534/Genetics.106.058362  0.793
2006 Swinburne IA, Meyer CA, Liu XS, Silver PA, Brodsky AS. Genomic localization of RNA binding proteins reveals links between pre-mRNA processing and transcription. Genome Research. 16: 912-21. PMID 16769980 DOI: 10.1101/Gr.5211806  0.779
2006 McKee AE, Silver PA. Systems biology of gene regulation fulfills its promise. Genome Biology. 7: 316. PMID 16719937 DOI: 10.1186/Gb-2006-7-5-316  0.676
2006 Drubin DA, Garakani AM, Silver PA. Motion as a phenotype: the use of live-cell imaging and machine visual screening to characterize transcription-dependent chromosome dynamics. Bmc Cell Biology. 7: 19. PMID 16635267 DOI: 10.1186/1471-2121-7-19  0.33
2006 Auld KL, Brown CR, Casolari JM, Komili S, Silver PA. Genomic association of the proteasome demonstrates overlapping gene regulatory activity with transcription factor substrates. Molecular Cell. 21: 861-71. PMID 16543154 DOI: 10.1016/J.Molcel.2006.02.020  0.804
2006 Bachand F, Lackner DH, Bähler J, Silver PA. Autoregulation of ribosome biosynthesis by a translational response in fission yeast. Molecular and Cellular Biology. 26: 1731-42. PMID 16478994 DOI: 10.1128/Mcb.26.5.1731-1742.2006  0.408
2006 Vandegraaff N, Devroe E, Turlure F, Silver PA, Engelman A. Biochemical and genetic analyses of integrase-interacting proteins lens epithelium-derived growth factor (LEDGF)/p75 and hepatoma-derived growth factor related protein 2 (HRP2) in preintegration complex function and HIV-1 replication. Virology. 346: 415-26. PMID 16337983 DOI: 10.1016/J.Virol.2005.11.022  0.791
2006 Hitchcock AL, Kahana JA, Silver PA. The uses of green fluorescent protein in yeasts. Methods of Biochemical Analysis. 47: 179-201. PMID 16335714 DOI: 10.1002/0471739499.Ch9  0.775
2005 Robinson MA, Park S, Sun ZY, Silver PA, Wagner G, Hogle JM. Multiple conformations in the ligand-binding site of the yeast nuclear pore-targeting domain of Nup116p. The Journal of Biological Chemistry. 280: 35723-32. PMID 16105837 DOI: 10.1074/Jbc.M505068200  0.306
2005 Brodsky AS, Meyer CA, Swinburne IA, Hall G, Keenan BJ, Liu XS, Fox EA, Silver PA. Genomic mapping of RNA polymerase II reveals sites of co-transcriptional regulation in human cells. Genome Biology. 6: R64. PMID 16086846 DOI: 10.1186/Gb-2005-6-8-R64  0.76
2005 McKee AE, Minet E, Stern C, Riahi S, Stiles CD, Silver PA. A genome-wide in situ hybridization map of RNA-binding proteins reveals anatomically restricted expression in the developing mouse brain. Bmc Developmental Biology. 5: 14. PMID 16033648 DOI: 10.1186/1471-213X-5-14  0.703
2005 Carroll JS, Liu XS, Brodsky AS, Li W, Meyer CA, Szary AJ, Eeckhoute J, Shao W, Hestermann EV, Geistlinger TR, Fox EA, Silver PA, Brown M. Chromosome-wide mapping of estrogen receptor binding reveals long-range regulation requiring the forkhead protein FoxA1. Cell. 122: 33-43. PMID 16009131 DOI: 10.1016/J.Cell.2005.05.008  0.337
2005 Casolari JM, Brown CR, Drubin DA, Rando OJ, Silver PA. Developmentally induced changes in transcriptional program alter spatial organization across chromosomes. Genes & Development. 19: 1188-98. PMID 15905407 DOI: 10.1101/Gad.1307205  0.345
2005 Schroeder FC, Kau TR, Silver PA, Clardy J. The psammaplysenes, specific inhibitors of FOXO1a nuclear export. Journal of Natural Products. 68: 574-6. PMID 15844952 DOI: 10.1021/Np049624Z  0.781
2005 Devroe E, Silver PA, Engelman A. HIV-1 incorporates and proteolytically processes human NDR1 and NDR2 serine-threonine kinases. Virology. 331: 181-9. PMID 15582665 DOI: 10.1016/J.Virol.2004.10.023  0.775
2004 Hieronymus H, Silver PA. A systems view of mRNP biology. Genes & Development. 18: 2845-60. PMID 15574591 DOI: 10.1101/Gad.1256904  0.726
2004 Lu R, Limón A, Devroe E, Silver PA, Cherepanov P, Engelman A. Class II integrase mutants with changes in putative nuclear localization signals are primarily blocked at a postnuclear entry step of human immunodeficiency virus type 1 replication. Journal of Virology. 78: 12735-46. PMID 15542626 DOI: 10.1128/Jvi.78.23.12735-12746.2004  0.777
2004 Hieronymus H, Yu MC, Silver PA. Genome-wide mRNA surveillance is coupled to mRNA export. Genes & Development. 18: 2652-62. PMID 15489286 DOI: 10.1101/Gad.1241204  0.725
2004 Cherepanov P, Devroe E, Silver PA, Engelman A. Identification of an evolutionarily conserved domain in human lens epithelium-derived growth factor/transcriptional co-activator p75 (LEDGF/p75) that binds HIV-1 integrase. The Journal of Biological Chemistry. 279: 48883-92. PMID 15371438 DOI: 10.1074/Jbc.M406307200  0.785
2004 Turlure F, Devroe E, Silver PA, Engelman A. Human cell proteins and human immunodeficiency virus DNA integration. Frontiers in Bioscience : a Journal and Virtual Library. 9: 3187-208. PMID 15353349 DOI: 10.2741/1472  0.797
2004 Yu MC, Bachand F, McBride AE, Komili S, Casolari JM, Silver PA. Arginine methyltransferase affects interactions and recruitment of mRNA processing and export factors. Genes & Development. 18: 2024-35. PMID 15314027 DOI: 10.1101/Gad.1223204  0.805
2004 McKee AE, Silver PA. REF-ereeing the cytoplasmic fate of mRNA via nuclear export. Developmental Cell. 6: 740-2. PMID 15177019 DOI: 10.1016/J.Devcel.2004.05.014  0.709
2004 Bachand F, Silver PA. PRMT3 is a ribosomal protein methyltransferase that affects the cellular levels of ribosomal subunits. The Embo Journal. 23: 2641-50. PMID 15175657 DOI: 10.1038/Sj.Emboj.7600265  0.4
2004 Casolari JM, Brown CR, Komili S, West J, Hieronymus H, Silver PA. Genome-wide localization of the nuclear transport machinery couples transcriptional status and nuclear organization. Cell. 117: 427-39. PMID 15137937 DOI: 10.1016/S0092-8674(04)00448-9  0.798
2004 Casolari JM, Silver PA. Guardian at the gate: preventing unspliced pre-mRNA export. Trends in Cell Biology. 14: 222-5. PMID 15130577 DOI: 10.1016/J.Tcb.2004.03.007  0.329
2004 Devroe E, Erdjument-Bromage H, Tempst P, Silver PA. Human Mob proteins regulate the NDR1 and NDR2 serine-threonine kinases. The Journal of Biological Chemistry. 279: 24444-51. PMID 15067004 DOI: 10.1074/Jbc.M401999200  0.793
2004 Devroe E, Silver PA. Therapeutic potential of retroviral RNAi vectors. Expert Opinion On Biological Therapy. 4: 319-27. PMID 15006726 DOI: 10.1517/14712598.4.3.319  0.791
2004 Kau TR, Way JC, Silver PA. Nuclear transport and cancer: from mechanism to intervention. Nature Reviews. Cancer. 4: 106-17. PMID 14732865 DOI: 10.1038/Nrc1274  0.794
2003 Kau TR, Schroeder F, Ramaswamy S, Wojciechowski CL, Zhao JJ, Roberts TM, Clardy J, Sellers WR, Silver PA. A chemical genetic screen identifies inhibitors of regulated nuclear export of a Forkhead transcription factor in PTEN-deficient tumor cells. Cancer Cell. 4: 463-76. PMID 14706338 DOI: 10.1016/S1535-6108(03)00303-9  0.788
2003 Haggarty SJ, Koeller KM, Kau TR, Silver PA, Roberge M, Schreiber SL. Small molecule modulation of the human chromatid decatenation checkpoint. Chemistry & Biology. 10: 1267-79. PMID 14700634 DOI: 10.1016/J.Chembiol.2003.11.014  0.783
2003 Hitchcock AL, Auld K, Gygi SP, Silver PA. A subset of membrane-associated proteins is ubiquitinated in response to mutations in the endoplasmic reticulum degradation machinery. Proceedings of the National Academy of Sciences of the United States of America. 100: 12735-40. PMID 14557538 DOI: 10.1073/Pnas.2135500100  0.786
2003 Devroe E, Engelman A, Silver PA. Intracellular transport of human immunodeficiency virus type 1 integrase. Journal of Cell Science. 116: 4401-8. PMID 13130095 DOI: 10.1242/Jcs.00747  0.803
2003 Lei EP, Stern CA, Fahrenkrog B, Krebber H, Moy TI, Aebi U, Silver PA. Sac3 is an mRNA export factor that localizes to cytoplasmic fibrils of nuclear pore complex. Molecular Biology of the Cell. 14: 836-47. PMID 12631707 DOI: 10.1091/Mbc.E02-08-0520  0.803
2003 Kau TR, Silver PA. Nuclear transport as a target for cell growth. Drug Discovery Today. 8: 78-85. PMID 12565010 DOI: 10.1016/S1359-6446(02)02562-X  0.807
2003 Hieronymus H, Silver PA. Genome-wide analysis of RNA-protein interactions illustrates specificity of the mRNA export machinery. Nature Genetics. 33: 155-61. PMID 12524544 DOI: 10.1038/Ng1080  0.732
2003 Beilharz T, Egan B, Silver PA, Hofmann K, Lithgow T. Bipartite signals mediate subcellular targeting of tail-anchored membrane proteins in Saccharomyces cerevisiae. The Journal of Biological Chemistry. 278: 8219-23. PMID 12514182 DOI: 10.1074/Jbc.M212725200  0.353
2002 Brodsky AS, Silver PA. A microbead-based system for identifying and characterizing RNA-protein interactions by flow cytometry. Molecular & Cellular Proteomics : McP. 1: 922-9. PMID 12543929 DOI: 10.1074/Mcp.T200010-Mcp200  0.343
2002 Damelin M, Silver PA. In situ analysis of spatial relationships between proteins of the nuclear pore complex. Biophysical Journal. 83: 3626-36. PMID 12496130 DOI: 10.1016/S0006-3495(02)75363-0  0.74
2002 Lei EP, Silver PA. Intron status and 3'-end formation control cotranscriptional export of mRNA. Genes & Development. 16: 2761-6. PMID 12414728 DOI: 10.1101/Gad.1032902  0.716
2002 Limón A, Devroe E, Lu R, Ghory HZ, Silver PA, Engelman A. Nuclear localization of human immunodeficiency virus type 1 preintegration complexes (PICs): V165A and R166A are pleiotropic integrase mutants primarily defective for integration, not PIC nuclear import. Journal of Virology. 76: 10598-607. PMID 12368302 DOI: 10.1128/Jvi.76.21.10598-10607.2002  0.784
2002 Devroe E, Silver PA. Retrovirus-delivered siRNA. Bmc Biotechnology. 2: 15. PMID 12199908 DOI: 10.1186/1472-6750-2-15  0.803
2002 Moy TI, Silver PA. Requirements for the nuclear export of the small ribosomal subunit. Journal of Cell Science. 115: 2985-95. PMID 12082158  0.764
2002 Damelin M, Silver PA, Corbett AH. Nuclear protein transport. Methods in Enzymology. 351: 587-607. PMID 12073370 DOI: 10.1016/S0076-6879(02)51870-X  0.748
2002 Brodsky AS, Silver PA. Identifying proteins that affect mRNA localization in living cells. Methods (San Diego, Calif.). 26: 151-5. PMID 12054891 DOI: 10.1016/S1046-2023(02)00017-8  0.345
2002 Moy TI, Boettner D, Rhodes JC, Silver PA, Askew DS. Identification of a role for Saccharomyces cerevisiae Cgr1p in pre-rRNA processing and 60S ribosome subunit synthesis. Microbiology (Reading, England). 148: 1081-90. PMID 11932453 DOI: 10.1099/00221287-148-4-1081  0.769
2002 Damelin M, Simon I, Moy TI, Wilson B, Komili S, Tempst P, Roth FP, Young RA, Cairns BR, Silver PA. The genome-wide localization of Rsc9, a component of the RSC chromatin-remodeling complex, changes in response to stress. Molecular Cell. 9: 563-73. PMID 11931764 DOI: 10.1016/S1097-2765(02)00475-6  0.784
2002 Lei EP, Silver PA. Protein and RNA export from the nucleus. Developmental Cell. 2: 261-72. PMID 11879632 DOI: 10.1016/S1534-5807(02)00134-X  0.735
2001 Kahana JA, Silver PA. Use of the A. victoria green fluorescent protein to study protein dynamics in vivo. Current Protocols in Pharmacology / Editorial Board, S.J. Enna (Editor-in-Chief) ... [Et Al.]. Unit 6.6. PMID 21965077 DOI: 10.1002/0471141755.Ph0606S05  0.311
2001 Kahana JA, Silver PA. Use of the A. victoria green fluorescent protein to study protein dynamics in vivo. Current Protocols in Neuroscience / Editorial Board, Jacqueline N. Crawley ... [Et Al.]. Unit 5.15. PMID 18428498 DOI: 10.1002/0471142301.Ns0515S14  0.335
2001 Kahana JA, Silver PA. Use of the A. victoria green fluorescent protein to study protein dynamics in vivo. Current Protocols in Molecular Biology / Edited by Frederick M. Ausubel ... [Et Al.]. Unit9.7C. PMID 18265287 DOI: 10.1002/0471142727.Mb0907Cs34  0.311
2001 Hitchcock AL, Krebber H, Frietze S, Lin A, Latterich M, Silver PA. The conserved npl4 protein complex mediates proteasome-dependent membrane-bound transcription factor activation. Molecular Biology of the Cell. 12: 3226-41. PMID 11598205 DOI: 10.1091/Mbc.12.10.3226  0.801
2001 Tham WH, Wyithe JS, Ko Ferrigno P, Silver PA, Zakian VA. Localization of yeast telomeres to the nuclear periphery is separable from transcriptional repression and telomere stability functions. Molecular Cell. 8: 189-99. PMID 11511372 DOI: 10.1016/S1097-2765(01)00287-8  0.361
2001 Lei EP, Krebber H, Silver PA. Messenger RNAs are recruited for nuclear export during transcription. Genes & Development. 15: 1771-82. PMID 11459827 DOI: 10.1101/Gad.892401  0.716
2000 Brodsky AS, Silver PA. Pre-mRNA processing factors are required for nuclear export Rna. 6: 1737-1749. PMID 11142374 DOI: 10.1017/S1355838200001059  0.352
2000 Colas P, Cohen B, Ferrigno PK, Silver PA, Brent R. Targeted modification and transportation of cellular proteins Proceedings of the National Academy of Sciences of the United States of America. 97: 13720-13725. PMID 11106396 DOI: 10.1073/Pnas.97.25.13720  0.385
2000 Weiss VH, McBride AE, Soriano MA, Filman DJ, Silver PA, Hogle JM. The structure and oligomerization of the yeast arginine methyltransferase, Hmt1. Nature Structural Biology. 7: 1165-71. PMID 11101900 DOI: 10.1038/82028  0.326
2000 Stage-Zimmermann T, Schmidt U, Silver PA. Factors affecting nuclear export of the 60S ribosomal subunit in vivo Molecular Biology of the Cell. 11: 3777-3789. PMID 11071906 DOI: 10.1091/Mbc.11.11.3777  0.383
2000 Krebber H, Silver PA. Directing proteins to nucleus by fusion to nuclear localization signal tags Methods in Enzymology. 327: 283-296. PMID 11044991 DOI: 10.1016/S0076-6879(00)27284-4  0.385
2000 Hood JK, Silver PA. Diverse nuclear transport pathways regulate cell proliferation and oncogenesis Biochimica Et Biophysica Acta - Reviews On Cancer. 1471: M31-M41. PMID 10967423 DOI: 10.1016/S0304-419X(00)00018-4  0.329
2000 Prinz WA, Grzyb L, Veenhuis M, Kahana JA, Silver PA, Rapoport TA. Mutants affecting the structure of the cortical endoplasmic reticulum in Saccharomyces cerevisiae. The Journal of Cell Biology. 150: 461-74. PMID 10931860 DOI: 10.1083/Jcb.150.3.461  0.31
2000 Shen EC, Stage-Zimmermann T, Chui P, Silver PA. 7The yeast mRNA-binding protein Npl3p interacts with the cap-binding complex. The Journal of Biological Chemistry. 275: 23718-24. PMID 10823828 DOI: 10.1074/Jbc.M002312200  0.709
2000 Jones AL, Booth Quimby B, Hood JK, Ferrigno P, Keshava PH, Silver PA, Corbett AH. SAC3 may link nuclear protein export to cell cycle progression Proceedings of the National Academy of Sciences of the United States of America. 97: 3224-3229. PMID 10716708 DOI: 10.1073/Pnas.97.7.3224  0.406
2000 Damelin M, Silver PA. Mapping interactions between nuclear transport factors in living cells reveals pathways through the nuclear pore complex Molecular Cell. 5: 133-140. PMID 10678175 DOI: 10.1016/S1097-2765(00)80409-8  0.744
2000 McBride AE, Weiss VH, Kim HK, Hogle JM, Silver PA. Analysis of the yeast arginine methyltransferase Hmt1p/Rmt1p and its in vivo function. Cofactor binding and substrate interactions. The Journal of Biological Chemistry. 275: 3128-36. PMID 10652296 DOI: 10.1074/Jbc.275.5.3128  0.36
2000 Guarente L, Silver PA. Nucleus and gene expression: Function following form in the nucleus Current Opinion in Cell Biology. 12: 279. DOI: 10.1016/S0955-0674(00)00088-0  0.511
1999 Ferrigno P, Silver PA. Regulated nuclear localization of stress-responsive factors: How the nuclear trafficking of protein kinases and transcription factors contributes to cell survival Oncogene. 18: 6129-6134. PMID 10557104 DOI: 10.1038/Sj.Onc.1203132  0.377
1999 Morehouse H, Buratowski RM, Silver PA, Buratowski S. The importin/karyopherin Kap114 mediates the nuclear import of TATA-binding protein. Proceedings of the National Academy of Sciences of the United States of America. 96: 12542-7. PMID 10535958 DOI: 10.1073/Pnas.96.22.12542  0.384
1999 Moy TI, Silver PA. Nuclear export of the small ribosomal subunit requires the ran-GTPase cycle and certain nucleoporins. Genes & Development. 13: 2118-33. PMID 10465789 DOI: 10.1101/Gad.13.16.2118  0.771
1999 Krebber H, Taura T, Lee MS, Silver PA. Uncoupling of hnRNP Npl3p from mRNAs during the stress-induced block in mRNA export Genes and Development. 13: 1994-2004. PMID 10444597 DOI: 10.1101/Gad.13.15.1994  0.344
1999 Zeng X, Kahana JA, Silver PA, Morphew MK, McIntosh JR, Fitch IT, Carbon J, Saunders WS. Slk19p is a centromere protein that functions to stabilize mitotic spindles. The Journal of Cell Biology. 146: 415-25. PMID 10427094 DOI: 10.1083/Jcb.146.2.415  0.346
1999 Defossez PA, Prusty R, Kaeberlein M, Lin SJ, Ferrigno P, Silver PA, Keil RL, Guarente L. Elimination of replication block protein Fob1 extends the life span of yeast mother cells Molecular Cell. 3: 447-455. PMID 10230397 DOI: 10.1016/S1097-2765(00)80472-4  0.543
1999 Hood JK, Silver PA. In or out? Regulating nuclear transport Current Opinion in Cell Biology. 11: 241-247. PMID 10209150 DOI: 10.1016/S0955-0674(99)80032-5  0.397
1999 Valentini SR, Weiss VH, Silver PA. Arginine methylation and binding of Hrp1p to the efficiency element for mRNA 3'-end formation. Rna (New York, N.Y.). 5: 272-80. PMID 10024178 DOI: 10.1017/S1355838299981633  0.309
1999 Seedorf M, Damelin M, Kahana J, Taura T, Silver PA. Interactions between a nuclear transporter and a subset of nuclear pore complex proteins depend on Ran GTPase. Molecular and Cellular Biology. 19: 1547-57. PMID 9891088 DOI: 10.1128/Mcb.19.2.1547  0.737
1999 Ferrigno P, Silver PA. Analysis of nuclear transport in vivo Methods in Cell Biology. 107-122. DOI: 10.1016/S0091-679X(08)61951-2  0.42
1998 Hood JK, Silver PA. Cse1p Is Required for Export of Srp1p/Importin-α from the Nucleus in Saccharomyces cerevisiae Journal of Biological Chemistry. 273: 35142-35146. PMID 9857050 DOI: 10.1074/Jbc.273.52.35142  0.319
1998 Silberstein S, Schlenstedt G, Silver PA, Gilmore R. A Role For The Dnaj Homologue Scj1P In Protein Folding In The Yeast Endoplasmic Reticulum Journal of Cell Biology. 143: 921-933. PMID 9817751 DOI: 10.1083/Jcb.143.4.921  0.376
1998 Ferrigno P, Posas F, Koepp D, Saito H, Silver PA. Regulated nucleo/cytoplasmic exchange of HOG1 MAPK requires the importin beta homologs NMD5 and XPO1. The Embo Journal. 17: 5606-14. PMID 9755161 DOI: 10.1093/Emboj/17.19.5606  0.72
1998 Kahana JA, Schlenstedt G, Evanchuk DM, Geiser JR, Hoyt MA, Silver PA. The yeast dynactin complex is involved in partitioning the mitotic spindle between mother and daughter cells during anaphase B. Molecular Biology of the Cell. 9: 1741-56. PMID 9658168 DOI: 10.1091/Mbc.9.7.1741  0.367
1998 Taura T, Krebber H, Silver PA. A member of the Ran-binding protein family, Yrb2p, is involved in nuclear protein export. Proceedings of the National Academy of Sciences of the United States of America. 95: 7427-32. PMID 9636166 DOI: 10.1073/Pnas.95.13.7427  0.383
1998 Koepp DM, Silver PA. Nucleocytoplasmic transport and cell proliferation Biochimica Et Biophysica Acta - Reviews On Cancer. 1377. PMID 9606975 DOI: 10.1016/S0304-419X(97)00036-X  0.693
1998 Scott HS, Antonarakis SE, Lalioti MD, Rossier C, Silver PA, Henry MF. Identification and characterization of two putative human arginine methyltransferases (HRMT1L1 and HRMT1L2) Genomics. 48: 330-340. PMID 9545638 DOI: 10.1006/Geno.1997.5190  0.396
1998 Shen EC, Henry MF, Weiss VH, Valentini SR, Silver PA, Lee MS. Arginine methylation facilitates the nuclear export of hnRNP proteins. Genes & Development. 12: 679-91. PMID 9499403 DOI: 10.1101/Gad.12.5.679  0.687
1998 Vodicka MA, Koepp DM, Silver PA, Emerman M. HIV-1 Vpr interacts with the nuclear transport pathway to promote macrophage infection. Genes & Development. 12: 175-85. PMID 9436978 DOI: 10.1101/Gad.12.2.175  0.716
1998 Taura T, Schlenstedt G, Silver PA. Yrb2p is a nuclear protein that interacts with Prp20p, a yeast Rcc1 homologue. The Journal of Biological Chemistry. 272: 31877-84. PMID 9395535 DOI: 10.1074/Jbc.272.50.31877  0.338
1997 Kessler MM, Henry MF, Shen E, Zhao J, Gross S, Silver PA, Moore CL. Hrp1, a sequence-specific RNA-binding protein that shuttles between the nucleus and the cytoplasm, is required for mRNA 3'-end formation in yeast. Genes & Development. 11: 2545-56. PMID 9334319 DOI: 10.1101/Gad.11.19.2545  0.696
1997 Seedorf M, Silver PA. Importin/karyopherin protein family members required for mRNA export from the nucleus. Proceedings of the National Academy of Sciences of the United States of America. 94: 8590-5. PMID 9238021 DOI: 10.1073/Pnas.94.16.8590  0.394
1997 Wong DH, Corbett AH, Kent HM, Stewart M, Silver PA. Interaction between the small GTPase Ran/Gsp1p and Ntf2p is required for nuclear transport Molecular and Cellular Biology. 17: 3755-3767. PMID 9199309 DOI: 10.1128/Mcb.17.7.3755  0.354
1997 Campbell KS, Mullane KP, Aksoy IA, Stubdal H, Zalvide J, Pipas JM, Silver PA, Roberts TM, Schaffhausen BS, DeCaprio JA. DnaJ/hsp40 chaperone domain of SV40 large T antigen promotes efficient viral DNA replication Genes and Development. 11: 1098-1110. PMID 9159391 DOI: 10.1101/Gad.11.9.1098  0.307
1997 Lithgow T, Cuezva JM, Silver PA. Highways for protein delivery to the mitochondria. Trends in Biochemical Sciences. 22: 110-3. PMID 9149527 DOI: 10.1016/S0968-0004(97)01007-4  0.39
1997 Lee MS, Silver PA. RNA movement between the nucleus and the cytoplasm. Current Opinion in Genetics & Development. 7: 212-9. PMID 9115427 DOI: 10.1016/S0959-437X(97)80131-1  0.33
1997 DeHoratius C, Silver PA. Nuclear transport defects and nuclear envelope alterations are associated with mutation of the Saccharomyces cerevisiae NPL4 gene. Molecular Biology of the Cell. 7: 1835-55. PMID 8930904 DOI: 10.1091/Mbc.7.11.1835  0.41
1997 Corbett AH, Silver PA. Nucleocytoplasmic transport of macromolecules. Microbiology and Molecular Biology Reviews : Mmbr. 61: 193-211. DOI: 10.1128/.61.2.193-211.1997  0.348
1996 Corbett A, Ferrigno P, Henry M, Kahana J, Koepp D, Lee M, Nguyen L, Schlenstedt G, Seedorf M, Shen E, Taura T, Wong D, Silver P. Genetic analysis of macromolecular transport across the nuclear envelope. Experimental Cell Research. 229: 212-6. PMID 8986600 DOI: 10.1006/Excr.1996.0362  0.8
1996 Koepp DM, Silver PA. A GTPase controlling nuclear trafficking: Running the right way or walking RANdomly? Cell. 87: 1-4. PMID 8858141 DOI: 10.1016/S0092-8674(00)81315-X  0.738
1996 Corbett AH, Silver PA. The NTF2 gene encodes an essential, highly conserved protein that functions in nuclear transport in vivo. The Journal of Biological Chemistry. 271: 18477-84. PMID 8702493 DOI: 10.1074/Jbc.271.31.18477  0.41
1996 Koepp DM, Wong DH, Corbett AH, Silver PA. Dynamic localization of the nuclear import receptor and its interactions with transport factors Journal of Cell Biology. 133: 1163-1176. PMID 8682856 DOI: 10.1083/Jcb.133.6.1163  0.73
1996 Lee MS, Henry M, Silver PA. A protein that shuttles between the nucleus and the cytoplasm is an important mediator of RNA export. Genes & Development. 10: 1233-46. PMID 8675010 DOI: 10.1101/Gad.10.10.1233  0.331
1996 Henry MF, Silver PA. A novel methyltransferase (Hmt1p) modifies poly(A)+-RNA-binding proteins. Molecular and Cellular Biology. 16: 3668-78. PMID 8668183 DOI: 10.1128/Mcb.16.7.3668  0.428
1995 Schlenstedt G, Saavedra C, Loeb JD, Cole CN, Silver PA. The GTP-bound form of the yeast Ran/TC4 homologue blocks nuclear protein import and appearance of poly(A)+ RNA in the cytoplasm. Proceedings of the National Academy of Sciences of the United States of America. 92: 225-9. PMID 7816822 DOI: 10.1073/Pnas.92.1.225  0.406
1995 Schlenstedt G, Harris S, Risse B, Lill R, Silver PA. A yeast DnaJ homologue, Scj1p, can function in the endoplasmic reticulum with BiP/Kar2p via a conserved domain that specifies interactions with Hsp70s. The Journal of Cell Biology. 129: 979-88. PMID 7744969 DOI: 10.1083/Jcb.129.4.979  0.572
1995 Corbett AH, Koepp DM, Schlenstedt G, Lee MS, Hopper AK, Silver PA. Rna1p, a Ran/TC4 GTPase activating protein, is required for nuclear import Journal of Cell Biology. 130: 1017-1026. PMID 7657689 DOI: 10.1083/Jcb.130.5.1017  0.754
1995 Loeb JD, Schlenstedt G, Pellman D, Kornitzer D, Silver PA, Fink GR. The yeast nuclear import receptor is required for mitosis. Proceedings of the National Academy of Sciences of the United States of America. 92: 7647-51. PMID 7644471 DOI: 10.1073/Pnas.92.17.7647  0.381
1995 Kahana JA, Schnapp BJ, Silver PA. Kinetics of spindle pole body separation in budding yeast. Proceedings of the National Academy of Sciences of the United States of America. 92: 9707-11. PMID 7568202 DOI: 10.1073/Pnas.92.21.9707  0.33
1995 Schlenstedt G, Wong DH, Koepp DM, Silver PA. Mutants in a yeast Ran binding protein are defective in nuclear transport Embo Journal. 14: 5367-5378. PMID 7489726 DOI: 10.1002/J.1460-2075.1995.Tb00221.X  0.749
1994 Osborne MA, Schlenstedt G, Jinks T, Silver PA. Nuf2, a spindle pole body-associated protein required for nuclear division in yeast Journal of Cell Biology. 125: 853-866. PMID 8188751 DOI: 10.1083/Jcb.125.4.853  0.378
1994 Flach J, Bossie M, Vogel J, Corbett A, Jinks T, Willins DA, Silver PA. A yeast RNA-binding protein shuttles between the nucleus and the cytoplasm. Molecular and Cellular Biology. 14: 8399-407. PMID 7969175 DOI: 10.1128/Mcb.14.12.8399  0.37
1993 Osborne MA, Silver PA. Nucleocytoplasmic transport in the yeast Saccharomyces cerevisiae Annual Review of Biochemistry. 62: 219-254. PMID 8352590 DOI: 10.1146/Annurev.Bi.62.070193.001251  0.391
1993 Wiedmann B, Silver P, Schunck WH, Wiedmann M. Overexpression of the ER-membrane protein P-450 CYP52A3 mimics sec mutant characteristics in Saccharomyces cerevisiae Bba - Biomembranes. 1153: 267-276. PMID 8274497 DOI: 10.1016/0005-2736(93)90415-V  0.328
1993 Kurihara T, Silver P. Suppression of a sec63 mutation identifies a novel component of the yeast endoplasmic reticulum translocation apparatus. Molecular Biology of the Cell. 4: 919-930. PMID 8257794 DOI: 10.1091/Mbc.4.9.919  0.352
1993 Schlenstedt G, Hurt E, Doye V, Silver PA. Reconstitution of nuclear protein transport with semi-intact yeast cells Journal of Cell Biology. 123: 785-798. PMID 8227140 DOI: 10.1083/Jcb.123.4.785  0.381
1993 Bossie MA, Silver PA. Movement of macromolecules between the cytoplasm and the nucleus in yeast. Current Opinion in Genetics & Development. 2: 768-74. PMID 1458025 DOI: 10.1016/S0959-437X(05)80137-6  0.383
1992 Stochaj U, Silver PA. A conserved phosphoprotein that specifically binds nuclear localization sequences is involved in nuclear import. Journal of Cell Biology. 117: 473-482. PMID 1572892 DOI: 10.1083/Jcb.117.3.473  0.365
1992 Bossie MA, DeHoratius C, Barcelo G, Silver P. A mutant nuclear protein with similarity to RNA binding proteins interferes with nuclear import in yeast. Molecular Biology of the Cell. 3: 875-93. PMID 1392078 DOI: 10.1091/Mbc.3.8.875  0.397
1992 Kurihara T, Silver PA. Chapter 25 DnaJ homologs and protein transport New Comprehensive Biochemistry. 22: 309-327. DOI: 10.1016/S0167-7306(08)60102-7  0.364
1991 Stochaj U, Osborne M, Kurihara T, Silver P. A yeast protein that binds nuclear localization signals: Purification localization, and antibody inhibition of binding activity Journal of Cell Biology. 113: 1243-1254. PMID 2045410 DOI: 10.1083/Jcb.113.6.1243  0.356
1991 Blumberg H, Silver PA. A homologue of the bacterial heat-shock gene DnaJ that alters protein sorting in yeast. Nature. 349: 627-30. PMID 2000136 DOI: 10.1038/349627A0  0.375
1991 Silver PA. How proteins enter the nucleus. Cell. 64: 489-497. PMID 1991319 DOI: 10.1016/0092-8674(91)90233-O  0.379
1991 Blumberg H, Silver P. A split zinc-finger protein is required for normal yeast growth. Gene. 107: 101-110. PMID 1743508 DOI: 10.1016/0378-1119(91)90302-R  0.384
1990 Sadler I, Chiang A, Kurihara T, Rothblatt J, Way J, Silver P. A yeast gene important for protein assembly into the endoplasmic reticulum and the nucleus has homology to DnaJ, an Escherichia coli heat shock protein. The Journal of Cell Biology. 109: 2665-75. PMID 2556404 DOI: 10.1083/Jcb.109.6.2665  0.393
1989 Silver P, Sadler I, Osborne MA. Yeast proteins that recognize nuclear localization sequences Journal of Cell Biology. 109: 983-989. PMID 2670959 DOI: 10.1083/Jcb.109.3.983  0.328
1989 Silver P, Goodson H. Nuclear protein transport Critical Reviews in Biochemistry and Molecular Biology. 24: 419-435. PMID 2670452 DOI: 10.3109/10409238909082557  0.346
1989 Nelson M, Silver P. Context affects nuclear protein localization in Saccharomyces cerevisiae. Molecular and Cellular Biology. 9: 384-9. PMID 2496300 DOI: 10.1128/Mcb.9.2.384  0.314
1988 Silver PA, Chiang A, Sadler I. Mutations that alter both localization and production of a yeast nuclear protein. Genes & Development. 2: 707-717. PMID 3138162 DOI: 10.1101/Gad.2.6.707  0.343
1986 Silver PA, Brent R, Ptashne M. DNA binding is not sufficient for nuclear localization of regulatory proteins in Saccharomyces cerevisiae. Molecular and Cellular Biology. 6: 4763-6. PMID 3099172 DOI: 10.1128/Mcb.6.12.4763  0.574
1984 Silver PA, Keegan LP, Ptashne M. Amino terminus of the yeast GAL4 gene product is sufficient for nuclear localization. Proceedings of the National Academy of Sciences of the United States of America. 81: 5951-5. PMID 6091123 DOI: 10.1073/Pnas.81.19.5951  0.703
1983 Watts C, Goodman JM, Silver P, Wickner W. Analysis of M13 procoat assembly into membranes in vitro. Methods in Enzymology. 97: 130-8. PMID 6361469 DOI: 10.1016/0076-6879(83)97126-4  0.709
1983 Silver P, Wickner W. Genetic mapping of the Escherichia coli leader (signal) peptidase gene (lep): A new approach for determining the map position of a cloned gene Journal of Bacteriology. 154: 569-572. PMID 6341355  0.468
1983 Sudate T, Silver P, Wickner W. [4] Molecular genetics of Escherichia coli leader peptidase Methods in Enzymology. 97: 46-57. PMID 6318034 DOI: 10.1016/0076-6879(83)97117-3  0.584
1982 Wolfe PB, Silver P, Wickner W. The isolation of homogeneous leader peptidase from a strain of Escherichia coli which overproduces the enzyme Journal of Biological Chemistry. 257: 7898-7902. PMID 6282859  0.501
1981 Watts C, Silver P, Wickner W. Membrane assembly from purified components. II. Assembly of M13 procoat into liposomes reconstituted with purified leader peptidase Cell. 25: 347-353. PMID 7026043 DOI: 10.1016/0092-8674(81)90053-2  0.553
1981 Silver P, Watts C, Wickner W. Membrane assembly from purified components. I. Isolated M13 procoat does not require ribosomes or soluble proteins for processing by membranes Cell. 25: 341-345. PMID 7026042 DOI: 10.1016/0092-8674(81)90052-0  0.56
1980 Silver P, Wickner WT. Role of M13 gene 1 protein in filamentous virus assembly Journal of Virology. 35: 256-258. PMID 7411692 DOI: 10.1128/Jvi.35.1.256-258.1980  0.543
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