Randall J. Kimple, Ph.D. - Publications

Affiliations: 
2003 University of North Carolina, Chapel Hill, Chapel Hill, NC 
Area:
Pharmacology, General Biophysics, Molecular Biology

62/189 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Rosenberg SA, Francis D, Hullett CR, Morris ZS, Fisher MM, Brower JV, Bradley KA, Anderson BM, Bassetti MF, Kimple RJ. Readability of Online Patient Educational Resources Found on NCI-Designated Cancer Center Web Sites. Journal of the National Comprehensive Cancer Network : Jnccn. 14: 735-40. PMID 27283166 DOI: 10.6004/Jnccn.2016.0075  0.64
2016 Campos D, Peeters W, Nickel K, Burkel B, Bussink J, Kimple RJ, van der Kogel A, Eliceiri KW, Kissick MW. Radiation Promptly Alters Cancer Live Cell Metabolic Fluxes: An In Vitro Demonstration. Radiation Research. 185: 496-504. PMID 27128739 DOI: 10.1667/Rr14093.1  0.64
2015 Romick-Rosendale LE, Hoskins EE, Privette Vinnedge LM, Foglesong GD, Brusadelli MG, Potter SS, Komurov K, Brugmann SA, Lambert P, Kimple RJ, Virts EL, Hanenberg H, Gillison ML, Wells SI. Defects in the Fanconi anemia pathway in head and neck cancer cells stimulate tumor cell invasion through DNA-PK and Rac1 signaling. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 26603260 DOI: 10.1158/1078-0432.Ccr-15-2209  0.64
2015 Fru LC, Adamson EB, Campos DD, Fain SB, Jacques SL, van der Kogel AJ, Nickel KP, Song C, Kimple RJ, Kissick MW. Potential role of the glycolytic oscillator in acute hypoxia in tumors. Physics in Medicine and Biology. 60: 9215-9225. PMID 26576743 DOI: 10.1088/0031-9155/60/24/9215  0.64
2015 Francis DM, Huang S, Armstrong EA, Werner LR, Hullett CR, Li C, Morris ZS, Swick AD, Kragh M, Lantto J, Kimple RJ, Harari PM. Pan-HER receptor inhibition augments radiation response in human lung and head and neck cancer models. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 26420857 DOI: 10.1158/1078-0432.Ccr-15-1664  0.64
2015 Swick AD, Chatterjee A, De Costa AA, Kimple RJ. Modulation of therapeutic sensitivity by human papillomavirus. Radiotherapy and Oncology : Journal of the European Society For Therapeutic Radiology and Oncology. PMID 26364887 DOI: 10.1016/J.Radonc.2015.09.002  0.64
2015 Liang E, Brower JV, Rice SR, Buehler DG, Saha S, Kimple RJ. Merkel Cell Carcinoma Analysis of Outcomes: A 30-Year Experience. Plos One. 10: e0129476. PMID 26053480 DOI: 10.1371/Journal.Pone.0129476  0.64
2015 Stein AP, Saha S, Kraninger JL, Swick AD, Yu M, Lambert PF, Kimple RJ. Prevalence of Human Papillomavirus in Oropharyngeal Cancer: A Systematic Review. Cancer Journal (Sudbury, Mass.). 21: 138-46. PMID 26049691 DOI: 10.1097/Ppo.0000000000000115  0.64
2015 Brand TM, Iida M, Stein AP, Corrigan KL, Braverman CM, Coan JP, Pearson HE, Bahrar H, Fowler TL, Bednarz BP, Saha S, Yang D, Gill PS, Lingen MW, Saloura V, ... ... Kimple RJ, et al. AXL Is a Logical Molecular Target in Head and Neck Squamous Cell Carcinoma. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 21: 2601-12. PMID 25767293 DOI: 10.1158/1078-0432.Ccr-14-2648  0.64
2015 Stein AP, Swick AD, Smith MA, Blitzer GC, Yang RZ, Saha S, Harari PM, Lambert PF, Liu CZ, Kimple RJ. Xenograft assessment of predictive biomarkers for standard head and neck cancer therapies. Cancer Medicine. 4: 699-712. PMID 25619980 DOI: 10.1002/Cam4.387  0.32
2015 Fowler TL, Bailey AM, Bednarz BP, Kimple RJ. High-throughput detection of DNA double-strand breaks using image cytometry. Biotechniques. 58: 37-9. PMID 25605579 DOI: 10.2144/000114248  0.64
2015 Adams AK, Hallenbeck GE, Casper KA, Patil YJ, Wilson KM, Kimple RJ, Lambert PF, Witte DP, Xiao W, Gillison ML, Wikenheiser-Brokamp KA, Wise-Draper TM, Wells SI. DEK promotes HPV-positive and -negative head and neck cancer cell proliferation. Oncogene. 34: 868-77. PMID 24608431 DOI: 10.1038/Onc.2014.15  0.64
2014 Zhang K, Jones L, Lim S, Maher CA, Adkins D, Lewis J, Kimple RJ, Fertig EJ, Chung CH, Van Tine BA, Ellis MJ, Herrlich A, Michel LS. Loss of Trop2 causes ErbB3 activation through a neuregulin-1-dependent mechanism in the mesenchymal subtype of HNSCC. Oncotarget. 5: 9281-94. PMID 25238142 DOI: 10.18632/Oncotarget.2423  0.64
2014 Park JW, Nickel KP, Torres AD, Lee D, Lambert PF, Kimple RJ. Human papillomavirus type 16 E7 oncoprotein causes a delay in repair of DNA damage. Radiotherapy and Oncology : Journal of the European Society For Therapeutic Radiology and Oncology. 113: 337-44. PMID 25216575 DOI: 10.1016/J.Radonc.2014.08.026  0.64
2014 Brand TM, Iida M, Stein AP, Corrigan KL, Braverman CM, Luthar N, Toulany M, Gill PS, Salgia R, Kimple RJ, Wheeler DL. AXL mediates resistance to cetuximab therapy. Cancer Research. 74: 5152-64. PMID 25136066 DOI: 10.1158/0008-5472.Can-14-0294  0.64
2014 Stein AP, Saha S, Liu CZ, Hartig GK, Lambert PF, Kimple RJ. Influence of handling conditions on the establishment and propagation of head and neck cancer patient derived xenografts. Plos One. 9: e100995. PMID 24967635 DOI: 10.1371/Journal.Pone.0100995  0.64
2014 Stein AP, Saha S, Yu M, Kimple RJ, Lambert PF. Prevalence of human papillomavirus in oropharyngeal squamous cell carcinoma in the United States across time. Chemical Research in Toxicology. 27: 462-9. PMID 24641254 DOI: 10.1021/Tx500034C  0.64
2014 Blitzer GC, Smith MA, Harris SL, Kimple RJ. Review of the clinical and biologic aspects of human papillomavirus-positive squamous cell carcinomas of the head and neck. International Journal of Radiation Oncology, Biology, Physics. 88: 761-70. PMID 24606845 DOI: 10.1016/J.Ijrobp.2013.08.029  0.64
2014 Fowler TL, Fulkerson RK, Micka JA, Kimple RJ, Bednarz BP. A novel high-throughput irradiator for in vitro radiation sensitivity bioassays. Physics in Medicine and Biology. 59: 1459-70. PMID 24584120 DOI: 10.1088/0031-9155/59/6/1459  0.64
2013 Kimple RJ, Smith MA, Blitzer GC, Torres AD, Martin JA, Yang RZ, Peet CR, Lorenz LD, Nickel KP, Klingelhutz AJ, Lambert PF, Harari PM. Enhanced radiation sensitivity in HPV-positive head and neck cancer. Cancer Research. 73: 4791-800. PMID 23749640 DOI: 10.1158/0008-5472.Can-13-0587  0.64
2013 Apisarnthanarax S, Swisher-McClure S, Chiu WK, Kimple RJ, Harris SL, Morris DE, Tepper JE. Applicability of randomized trials in radiation oncology to standard clinical practice. Cancer. 119: 3092-9. PMID 23674290 DOI: 10.1002/Cncr.28149  0.64
2013 Vanderwalde NA, Jones EL, Kimple RJ, Moore DT, Klauber-Demore N, Sartor CI, Ollila DW. Phase 2 study of pre-excision single-dose intraoperative radiation therapy for early-stage breast cancers: six-year update with application of the ASTRO accelerated partial breast irradiation consensus statement criteria. Cancer. 119: 1736-43. PMID 23361892 DOI: 10.1002/Cncr.27915  0.64
2013 Kimple RJ, Harari PM, Torres AD, Yang RZ, Soriano BJ, Yu M, Armstrong EA, Blitzer GC, Smith MA, Lorenz LD, Lee D, Yang DT, McCulloch TM, Hartig GK, Lambert PF. Development and characterization of HPV-positive and HPV-negative head and neck squamous cell carcinoma tumorgrafts. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 19: 855-64. PMID 23251001 DOI: 10.1158/1078-0432.Ccr-12-2746  0.64
2013 Kimple RJ, Kao GD. A 10-year analysis of American Society For Radiation Oncology Junior Faculty Career Development Awards. International Journal of Radiation Oncology, Biology, Physics. 85: 924-8. PMID 22929862 DOI: 10.1016/J.Ijrobp.2012.07.2361  0.64
2013 Smith MA, Blitzer GC, Torres AD, Armstrong EA, Lambert PF, Harari PM, Kimple RJ. Abstract 73: Preclinical evaluation of chemoradiation with cetuximab HPV-positive head and neck cancer suggests significant radiosensitization. Cancer Research. 73: 73-73. DOI: 10.1158/1538-7445.Am2013-73  0.32
2013 Blitzer GC, Smith MA, Torres AD, Armstrong EA, Harari PM, Lambert PF, Kimple RJ. Abstract 5474: Epidermal growth factor inhibition of HPV positive head and neck cancer cells and primary tumorgrafts results in significant growth inhibition mediated by apoptosis. Cancer Research. 73: 5474-5474. DOI: 10.1158/1538-7445.Am2013-5474  0.32
2012 Kimple RJ, Horton JK, Livasy CA, Shields JM, Lawrence JA, Chiu WM, Ivanova A, Ollila DW, Carey LA, Halle JS, Sartor CI, Dees EC. Phase I study and biomarker analysis of lapatinib and concurrent radiation for locally advanced breast cancer. The Oncologist. 17: 1496-503. PMID 23006498 DOI: 10.1634/Theoncologist.2012-0256  0.64
2012 Kimple AJ, Torres AD, Yang RZ, Kimple RJ. HPV-associated head and neck cancer: molecular and nano-scale markers for prognosis and therapeutic stratification. Sensors (Basel, Switzerland). 12: 5159-69. PMID 22666080 DOI: 10.3390/S120405159  0.64
2012 Torres AD, Kimple RJ, Yang RZ, Soriano B, Armstrong EA, Harari PM, Lambert PF. Abstract 2356: Establishment of HPV-positive and HPV-negative head and neck cancer tumorgrafts directly from patient biopsies Cancer Research. 72: 2356-2356. DOI: 10.1158/1538-7445.Am2012-2356  0.32
2012 Kimple RJ, Blitzer GC, Torres AD, Yang RZ, Lorenz LD, Armstrong EA, Soriano BJ, Lambert PF, Harari PM. Abstract 2352: Molecular profiles of head and neck cancer tumorgrafts Cancer Research. 72: 2352-2352. DOI: 10.1158/1538-7445.Am2012-2352  0.32
2011 Kimple RJ, Wallen KE, Person T, Erwin RN, Helmrath MA, Gold S, Morris DE. First use of electromagnetic setup and real-time tracking in a pediatric patient with vaginal rhabdomyosarcoma. Practical Radiation Oncology. 1: 47-51. PMID 24673871 DOI: 10.1016/J.Prro.2010.08.001  0.64
2011 Harris SL, Thorne LB, Seaman WT, Hayes DN, Couch ME, Kimple RJ. Association of p16(INK4a) overexpression with improved outcomes in young patients with squamous cell cancers of the oral tongue. Head & Neck. 33: 1622-7. PMID 21990227 DOI: 10.1002/Hed.21650  0.64
2011 Sambade MJ, Peters EC, Thomas NE, Kaufmann WK, Kimple RJ, Shields JM. Melanoma cells show a heterogeneous range of sensitivity to ionizing radiation and are radiosensitized by inhibition of B-RAF with PLX-4032. Radiotherapy and Oncology : Journal of the European Society For Therapeutic Radiology and Oncology. 98: 394-9. PMID 21295875 DOI: 10.1016/J.Radonc.2010.12.017  0.64
2011 Kimple RJ, Klauber-DeMore N, Kuzmiak CM, Pavic D, Lian J, Livasy CA, Chiu WM, Moore DT, Sartor CI, Ollila DW. Local control following single-dose intraoperative radiotherapy prior to surgical excision of early-stage breast cancer. Annals of Surgical Oncology. 18: 939-45. PMID 21061074 DOI: 10.1245/S10434-010-1392-6  0.64
2011 Kimple RJ, Klauber-DeMore N, Kuzmiak CM, Pavic D, Lian J, Livasy CA, Esler L, Moore DT, Sartor CI, Ollila DW. Cosmetic outcomes for accelerated partial breast irradiation before surgical excision of early-stage breast cancer using single-dose intraoperative radiotherapy. International Journal of Radiation Oncology, Biology, Physics. 79: 400-7. PMID 20395062 DOI: 10.1016/J.Ijrobp.2009.10.032  0.64
2011 Kimple RJ, Yang RZ, Armstrong EA, Lambert PF, Harari PM. Abstract 2721: Comparative responses of HPV-positive vs HPV-negative head and neck cancer cells to radiation and/or chemotherapeutic drugs Cancer Research. 71: 2721-2721. DOI: 10.1158/1538-7445.Am2011-2721  0.32
2011 Kimple RJ, Garden AS, Yang RZ, Wong SJ, Schwartz M, Curran WJ, Murphy BA, Chen AY, Ang KK, Harari PM. United States Patterns of Radiation Oncology Practice in the Longitudinal Oncology Registry of Head and Neck Carcinoma (LORHAN) Study International Journal of Radiation Oncology Biology Physics. 81. DOI: 10.1016/J.Ijrobp.2011.06.284  0.32
2010 Sambade MJ, Kimple RJ, Camp JT, Peters E, Livasy CA, Sartor CI, Shields JM. Lapatinib in combination with radiation diminishes tumor regrowth in HER2+ and basal-like/EGFR+ breast tumor xenografts. International Journal of Radiation Oncology, Biology, Physics. 77: 575-81. PMID 20457354 DOI: 10.1016/J.Ijrobp.2009.12.063  0.64
2010 Kimple AJ, Muller RE, Siderovski DP, Willard FS. A capture coupling method for the covalent immobilization of hexahistidine tagged proteins for surface plasmon resonance. Methods in Molecular Biology (Clifton, N.J.). 627: 91-100. PMID 20217615 DOI: 10.1007/978-1-60761-670-2_5  0.6
2010 Hutsell SQ, Kimple RJ, Siderovski DP, Willard FS, Kimple AJ. High-affinity immobilization of proteins using biotin- and GST-based coupling strategies. Methods in Molecular Biology (Clifton, N.J.). 627: 75-90. PMID 20217614 DOI: 10.1007/978-1-60761-670-2_4  0.84
2010 Kimple RJ, Vaseva AV, Cox AD, Baerman KM, Calvo BF, Tepper JE, Shields JM, Sartor CI. Radiosensitization of epidermal growth factor receptor/HER2-positive pancreatic cancer is mediated by inhibition of Akt independent of ras mutational status. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 16: 912-23. PMID 20103665 DOI: 10.1158/1078-0432.Ccr-09-1324  0.64
2010 Harris SL, Kimple RJ, Hayes DN, Couch ME, Rosenman JG. Never-smokers, never-drinkers: unique clinical subgroup of young patients with head and neck squamous cell cancers. Head & Neck. 32: 499-503. PMID 19691028 DOI: 10.1002/Hed.21220  0.64
2009 Sambade MJ, Camp JT, Kimple RJ, Sartor CI, Shields JM. Mechanism of lapatinib-mediated radiosensitization of breast cancer cells is primarily by inhibition of the Raf>MEK>ERK mitogen-activated protein kinase cascade and radiosensitization of lapatinib-resistant cells restored by direct inhibition of MEK. Radiotherapy and Oncology : Journal of the European Society For Therapeutic Radiology and Oncology. 93: 639-44. PMID 19853943 DOI: 10.1016/J.Radonc.2009.09.006  0.64
2009 Willard FS, Willard MD, Kimple AJ, Soundararajan M, Oestreich EA, Li X, Sowa NA, Kimple RJ, Doyle DA, Der CJ, Zylka MJ, Snider WD, Siderovski DP. Regulator of G-protein signaling 14 (RGS14) is a selective H-Ras effector. Plos One. 4: e4884. PMID 19319189 DOI: 10.1371/Journal.Pone.0004884  0.64
2009 Harris SL, Kimple RJ, Feinberg NH, Seaman WT, Hayes DN, Thorne LB, Couch ME. P16ink4a Over-expression is Associated with Improved Outcomes in Young Patients with Squamous Cell Cancers of the Oral Tongue International Journal of Radiation Oncology Biology Physics. 75. DOI: 10.1016/J.Ijrobp.2009.07.888  0.32
2008 Apisarnthanarax S, Kimple RJ, Harris SL, Morris DE, Tepper JE. Applicability of Randomized Trials in Radiation Oncology to Standard Clinical Practice at a Single Institution International Journal of Radiation Oncology Biology Physics. 72. DOI: 10.1016/J.Ijrobp.2008.06.1417  0.32
2008 Harris SL, Kimple RJ, Hayes DN, Couch ME, Rosenman JG. A Unique Subgroup of Young Patients with Head and Neck Cancer International Journal of Radiation Oncology Biology Physics. 72. DOI: 10.1016/J.Ijrobp.2008.06.1323  0.32
2007 Sammond DW, Eletr ZM, Purbeck C, Kimple RJ, Siderovski DP, Kuhlman B. Structure-based protocol for identifying mutations that enhance protein-protein binding affinities. Journal of Molecular Biology. 371: 1392-404. PMID 17603074 DOI: 10.1016/J.Jmb.2007.05.096  0.64
2005 McCudden CR, Willard FS, Kimple RJ, Johnston CA, Hains MD, Jones MB, Siderovski DP. G alpha selectivity and inhibitor function of the multiple GoLoco motif protein GPSM2/LGN. Biochimica Et Biophysica Acta. 1745: 254-64. PMID 15946753 DOI: 10.1016/J.Bbamcr.2005.05.002  0.84
2005 Webb CK, McCudden CR, Willard FS, Kimple RJ, Siderovski DP, Oxford GS. D2 dopamine receptor activation of potassium channels is selectively decoupled by Galpha-specific GoLoco motif peptides. Journal of Neurochemistry. 92: 1408-18. PMID 15748159 DOI: 10.1111/J.1471-4159.2004.02997.X  0.64
2005 McCudden CR, Hains MD, Kimple RJ, Siderovski DP, Willard FS. G-protein signaling: back to the future. Cellular and Molecular Life Sciences : Cmls. 62: 551-77. PMID 15747061 DOI: 10.1007/S00018-004-4462-3  0.84
2004 Martin-McCaffrey L, Willard FS, Oliveira-dos-Santos AJ, Natale DR, Snow BE, Kimple RJ, Pajak A, Watson AJ, Dagnino L, Penninger JM, Siderovski DP, D'Souza SJ. RGS14 is a mitotic spindle protein essential from the first division of the mammalian zygote. Developmental Cell. 7: 763-9. PMID 15525537 DOI: 10.1016/J.Devcel.2004.10.004  0.64
2004 Kimple RJ, Willard FS, Siderovski DP. Purification and in vitro functional analyses of RGS12 and RGS14 GoLoco motif peptides. Methods in Enzymology. 390: 416-36. PMID 15488192 DOI: 10.1016/S0076-6879(04)90026-2  0.84
2004 Willard FS, Kimple RJ, Kimple AJ, Johnston CA, Siderovski DP. Fluorescence-based assays for RGS box function. Methods in Enzymology. 389: 56-71. PMID 15313559 DOI: 10.1016/S0076-6879(04)89004-9  0.64
2004 Willard FS, Kimple RJ, Siderovski DP. Return of the GDI: the GoLoco motif in cell division. Annual Review of Biochemistry. 73: 925-51. PMID 15189163 DOI: 10.1146/Annurev.Biochem.73.011303.073756  0.84
2004 Kimple RJ, Willard FS, Hains MD, Jones MB, Nweke GK, Siderovski DP. Guanine nucleotide dissociation inhibitor activity of the triple GoLoco motif protein G18: alanine-to-aspartate mutation restores function to an inactive second GoLoco motif. The Biochemical Journal. 378: 801-8. PMID 14656218 DOI: 10.1042/Bj20031686  0.84
2003 Rojas RJ, Kimple RJ, Rossman KL, Siderovski DP, Sondek J. Established and emerging fluorescence-based assays for G-protein function: Ras-superfamily GTPases. Combinatorial Chemistry & High Throughput Screening. 6: 409-18. PMID 12769685 DOI: 10.2174/138620703106298509  0.64
2003 Kimple RJ, Jones MB, Shutes A, Yerxa BR, Siderovski DP, Willard FS. Established and emerging fluorescence-based assays for G-protein function: heterotrimeric G-protein alpha subunits and regulator of G-protein signaling (RGS) proteins. Combinatorial Chemistry & High Throughput Screening. 6: 399-407. PMID 12769684 DOI: 10.2174/138620703106298491  0.84
2003 Colombo K, Grill SW, Kimple RJ, Willard FS, Siderovski DP, Gönczy P. Translation of polarity cues into asymmetric spindle positioning in Caenorhabditis elegans embryos. Science (New York, N.Y.). 300: 1957-61. PMID 12750478 DOI: 10.1126/Science.1084146  0.84
2002 Kimple RJ, Willard FS, Siderovski DP. The GoLoco motif: heralding a new tango between G protein signaling and cell division. Molecular Interventions. 2: 88-100. PMID 14993354 DOI: 10.1124/Mi.2.2.88  0.84
2002 Kimple RJ, Kimple ME, Betts L, Sondek J, Siderovski DP. Structural determinants for GoLoco-induced inhibition of nucleotide release by Galpha subunits. Nature. 416: 878-81. PMID 11976690 DOI: 10.1038/416878A  0.64
2001 Kimple RJ, De Vries L, Tronchère H, Behe CI, Morris RA, Gist Farquhar M, Siderovski DP. RGS12 and RGS14 GoLoco motifs are G alpha(i) interaction sites with guanine nucleotide dissociation inhibitor Activity. The Journal of Biological Chemistry. 276: 29275-81. PMID 11387333 DOI: 10.1074/Jbc.M103208200  0.64
Low-probability matches
2010 Muller RE, Klein KR, Hutsell SQ, Siderovski DP, Kimple AJ. A homogeneous method to measure nucleotide exchange by α-subunits of heterotrimeric G-proteins using fluorescence polarization. Assay and Drug Development Technologies. 8: 621-4. PMID 20662737 DOI: 10.1089/Adt.2010.0286  0.28
2009 Tang X, Kimple R, Harris S, Foskey M, Tracton G, Chang S, Chaney E, Pizer S, Deschesne K. SU-FF-I-90: A Clinical Evaluation of the M-Rep-Based Automatic Prostate Segmentation Medical Physics. 36: 2455-2455. DOI: 10.1118/1.3181210  0.28
2009 Preininger AM, Funk MA, Oldham WM, Meier SM, Johnston CA, Adhikary S, Kimple AJ, Siderovski DP, Hamm HE, Iverson TM. Helix dipole movement and conformational variability contribute to allosteric GDP release in Galphai subunits. Biochemistry. 48: 2630-42. PMID 19222191 DOI: 10.1021/Bi801853A  0.16
2008 Kimple AJ, Yasgar A, Hughes M, Jadhav A, Willard FS, Muller RE, Austin CP, Inglese J, Ibeanu GC, Siderovski DP, Simeonov A. A high throughput fluorescence polarization assay for inhibitors of the GoLoco motif/G-alpha interaction. Combinatorial Chemistry & High Throughput Screening. 11: 396-409. PMID 18537560 DOI: 10.2174/138620708784534770  0.16
2021 Abel L, Durmaz A, Hu R, Longhurst C, Baschnagel AM, Wheeler D, Scott JG, Kimple RJ. Impact of immediate cryopreservation on the establishment of patient derived xenografts from head and neck cancer patients. Journal of Translational Medicine. 19: 180. PMID 33910584 DOI: 10.1186/s12967-021-02850-1  0.04
2014 Wojcieszynski A, Olson AK, Rong Y, Kimple RJ, Yadav P. Toxicity From Breast Cancer Treatment Using Helical Intensity Modulated Radiation Therapy With an Incorporated Boost International Journal of Radiation Oncology Biology Physics. 90. DOI: 10.1016/J.Ijrobp.2014.05.794  0.04
2010 Preininger AM, Funk MA, Meier SM, Oldham WM, Johnston CA, Adhikary S, Kimple AJ, Siderovski DP, Hamm HE, Iverson TM. Correction to Helix Dipole Movement and Conformational Variability Contribute to Allosteric GDP Release in GαiSubunits Biochemistry. 49: 10037-10037. DOI: 10.1021/Bi101656R  0.04
2008 Kimple RJ, Grabowski S, Papez M, Collichio F, Ewend MG, Morris DE. Glioblastoma in the elderly: Radiation, chemoradiation, and supportive care Journal of Clinical Oncology. 26: 20738-20738. DOI: 10.1200/Jco.2008.26.15_Suppl.20738  0.04
2004 Morton JM, Baker CC, Farrell TM, Yohe ME, Kimple RJ, Herman DC, Udekwu P, Galanko JA, Behrns KE, Meyer AA. What do surgery residents do on their call nights? American Journal of Surgery. 188: 225-9. PMID 15450824 DOI: 10.1016/J.Amjsurg.2004.06.011  0.04
2021 Smith SM, Wachter K, Burris HA, Schilsky RL, George DJ, Peterson DE, Johnson ML, Mileham KF, Beg M, Bendell JC, Dreicer R, Keedy VL, Kimple RJ, Knoll MA, LoConte N, et al. Clinical Cancer Advances 2021: ASCO's Report on Progress Against Cancer. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. JCO2003420. PMID 33527845 DOI: 10.1200/JCO.20.03420  0.01
2021 Karam SD, Anderson CM, Ma D, Chua MLK, Kimple RJ. Immunotherapy in Head and Neck Cancer-Ready for Prime Time or More Research Needed? International Journal of Radiation Oncology, Biology, Physics. 109: 647-650. PMID 33516431 DOI: 10.1016/j.ijrobp.2020.11.022  0.01
2021 Baschnagel AM, Kaushik S, Durmaz A, Goldstein S, Ong IM, Abel L, Clark PA, Gurel Z, Leal T, Buehler D, Iyer G, Scott JG, Kimple RJ. Development and characterization of patient-derived xenografts from non-small cell lung cancer brain metastases. Scientific Reports. 11: 2520. PMID 33510214 DOI: 10.1038/s41598-021-81832-1  0.01
2021 Marsiglio JA, Rosenberg DM, Rooney MK, Goodman CR, Gillespie EF, Hirsch AE, Holliday EB, Kimple RJ, Thomas CR, Golden DW. Mentorship initiatives in radiation oncology: A scoping review of the literature. International Journal of Radiation Oncology, Biology, Physics. PMID 33412265 DOI: 10.1016/j.ijrobp.2020.12.049  0.01
2020 McDaniel NK, Iida M, Nickel KP, Longhurst CA, Fischbach SR, Rodems TS, Kranjac CA, Bo AY, Luo Q, Gallagher MM, Welke NB, Mitchell KR, Schulz AE, Eckers JC, Hu R, ... ... Kimple RJ, et al. AXL mediates cetuximab and radiation resistance through tyrosine 821 and the c-ABL kinase pathway in head and neck cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 32439698 DOI: 10.1158/1078-0432.Ccr-19-3142  0.01
2020 Chua MLK, Ma DJ, Anderson CM, Karam SD, Margalit DN, Kimple RJ. Follow-up and management of head and neck cancer patients during the 2019 novel coronavirus (SARS-CoV-2) disease pandemic. Advances in Radiation Oncology. PMID 32426556 DOI: 10.1016/J.Adro.2020.04.031  0.01
2020 Poellmann MJ, Nair A, Bu J, Kim JKH, Kimple RJ, Hong S. Immunoavidity-based Capture of Tumor Exosomes using Poly(amidoamine) Dendrimer Surfaces. Nano Letters. PMID 32407121 DOI: 10.1021/Acs.Nanolett.0C00950  0.01
2020 SenthilKumar G, Fisher MM, Skiba JH, Miller MC, Brennan SR, Kaushik S, Bradley ST, Longhurst CA, Buehler D, Nickel KP, Iyer G, Kimple RJ, Baschnagel AM. FGFR inhibition enhances sensitivity to radiation in non-small cell lung cancer. Molecular Cancer Therapeutics. PMID 32371583 DOI: 10.1158/1535-7163.Mct-19-0931  0.01
2020 Fisher MM, SenthilKumar G, Hu R, Goldstein S, Ong I, Miller M, Brennan SR, Kaushik S, Abel L, Nickel KP, Iyer G, Harari PM, Kimple RJ, Baschnagel AM. Fibroblast Growth Factor Receptors as Targets for Radiosensitization in Head and Neck Squamous Cell Carcinomas. International Journal of Radiation Oncology, Biology, Physics. PMID 32298810 DOI: 10.1016/J.Ijrobp.2020.03.040  0.01
2020 Margalit DN, Karam SD, Chua MLK, Anderson C, Kimple RJ. Four Influential Clinical Trials in Human Papilloma Virus-Associated Oropharynx Cancer. International Journal of Radiation Oncology, Biology, Physics. 106: 893-899. PMID 32171456 DOI: 10.1016/J.Ijrobp.2019.12.015  0.01
2020 Fru LC, Jacques SL, Nickel KP, Varghese T, Kissick MW, DeWerd LA, Kimple RJ. Interstitial diffuse optical probe with spectral fitting to measure dynamic tumor hypoxia. Biomedical Physics & Engineering Express. 6. PMID 32095273 DOI: 10.1088/2057-1976/Ab6E16  0.01
2020 Cosper PF, Abel L, Lee YS, Paz C, Kaushik S, Nickel KP, Alexandridis R, Scott JG, Bruce JY, Kimple RJ. Patient Derived Models to Study Head and Neck Cancer Radiation Response. Cancers. 12. PMID 32059418 DOI: 10.3390/Cancers12020419  0.01
2020 Burr AR, Harari PM, Haasl AM, Wieland AM, Bruce JY, Kimple RJ, Hartig GK, McCulloch TM, Witek ME. Clinical outcomes for larynx patients with cancer treated with refinement of high-dose radiation treatment volumes. Head & Neck. PMID 32057151 DOI: 10.1002/Hed.26098  0.01
2020 Markham MJ, Wachter K, Agarwal N, Bertagnolli MM, Chang SM, Dale W, Diefenbach CSM, Rodriguez-Galindo C, George DJ, Gilligan TD, Harvey RD, Johnson ML, Kimple RJ, Knoll MA, LoConte N, et al. Clinical Cancer Advances 2020: Annual Report on Progress Against Cancer From the American Society of Clinical Oncology. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. JCO1903141. PMID 32013670 DOI: 10.1200/JCO.19.03141  0.01
2020 Burr A, Harari P, Griffith A, Kimple R, Witek M. Treatment Outcomes for Advanced Stage Hypopharyngeal Cancer Treated without a GTV to CTV Expansion International Journal of Radiation Oncology Biology Physics. 108. DOI: 10.1016/J.Ijrobp.2020.02.574  0.01
2020 Burr A, Harari P, Griffith A, Haasl A, Kimple R, Glazer T, Hartig G, McCulloch T, Witek M. Clinical Outcomes for Larynx Cancer Patients Treated with Refinement of High-Dose Radiation Treatment Volumes International Journal of Radiation Oncology Biology Physics. 108. DOI: 10.1016/J.Ijrobp.2020.02.567  0.01
2020 Witek M, Harari P, Burr A, Chandereng T, Bruce J, Kimple R, Avey G. Intra-Treatment PET/MRI Separates Intermediate Risk p16-Positive Oropharynx Cancer Patients into Favorable and Unfavorable Cohorts International Journal of Radiation Oncology Biology Physics. 108. DOI: 10.1016/J.Ijrobp.2020.02.562  0.01
2020 Lee YS, Skiba J, SenthilKumar G, Bradley ST, Nickel KP, Kimple RJ. Inhibition of radiation-induced autophagy improves control of head and neck squamous cell carcinoma International Journal of Radiation Oncology Biology Physics. 106: 1187. DOI: 10.1016/J.Ijrobp.2019.11.124  0.01
2019 Mittauer KE, Hill PM, Geurts MW, De Costa AM, Kimple RJ, Bassetti MF, Bayouth JE. STAT-ART: The Promise and Practice of a Rapid Palliative Single Session of MR-Guided Online Adaptive Radiotherapy (ART). Frontiers in Oncology. 9: 1013. PMID 31696053 DOI: 10.3389/Fonc.2019.01013  0.01
2019 Ayuso JM, Vitek R, Swick AD, Skala MC, Wisinski KB, Kimple RJ, Lambert PF, Beebe DJ. Effects of culture method on response to EGFR therapy in head and neck squamous cell carcinoma cells. Scientific Reports. 9: 12480. PMID 31462653 DOI: 10.1038/S41598-019-48764-3  0.01
2019 SenthilKumar G, Skiba JH, Kimple RJ. High-throughput quantitative detection of basal autophagy and autophagic flux using image cytometry. Biotechniques. PMID 31238709 DOI: 10.2144/Btn-2019-0044  0.01
2019 Anderson CM, Kimple RJ, Lin A, Karam SD, Margalit DN, Chua MLK. De-Escalation Strategies in HPV-Associated Oropharynx Cancer-Are we Putting the Cart Before the Horse? International Journal of Radiation Oncology, Biology, Physics. 104: 705-709. PMID 31204653 DOI: 10.1016/J.Ijrobp.2019.02.054  0.01
2019 Pasch CA, Favreau PF, Yueh AE, Babiarz CP, Gillette A, Sharick JT, Karim MR, Nickel KP, DeZeeuw AK, Sprackling CM, Emmerich PB, DeStefanis RA, Pitera RT, Payne SN, Korkos DP, ... ... Kimple RJ, et al. Patient-derived cancer organoid cultures to predict sensitivity to chemotherapy and radiation. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 31175091 DOI: 10.1158/1078-0432.Ccr-18-3590  0.01
2019 Burr AR, Harari PM, Ko HC, Bruce JY, Kimple RJ, Witek ME. Reducing radiotherapy target volume expansion for patients with HPV-associated oropharyngeal cancer. Oral Oncology. 92: 52-56. PMID 31010623 DOI: 10.1016/J.Oraloncology.2019.03.013  0.01
2019 Yu JB, Beck TF, Anscher MS, Baschnagel AM, Brock KK, Carlson DJ, Dominello MM, Kimple RJ, Knisely JPS, Mendonca MS, Mian OY, Singh AK, Moros EG, Keen JC. The ASTRO Research Portfolio: Where Do We Go From Here? International Journal of Radiation Oncology, Biology, Physics. 103: 308-309. PMID 30647008 DOI: 10.1016/J.Ijrobp.2018.09.009  0.01
2019 Yu JB, Beck TF, Anscher MS, Baschnagel AM, Brock KK, Carlson DJ, Dominello MM, Kimple RJ, Knisely JP, Mendonca MS, Mian OY, Singh AK, Moros EG, Keen JC. Analysis of the 2017 American Society for Radiation Oncology (ASTRO) Research Portfolio. International Journal of Radiation Oncology, Biology, Physics. 103: 297-304. PMID 30647006 DOI: 10.1016/J.Ijrobp.2018.07.2056  0.01
2019 Lee Y, Skiba J, Kubatzke J, Nickel KP, Kimple R. Abstract 4273: Inhibition of autophagy increases HNSCC sensitivity to cancer therapies Cancer Research. 79: 4273-4273. DOI: 10.1158/1538-7445.Am2019-4273  0.01
2019 SenthilKumar G, Miller M, Fisher M, Brennan S, Kaushik S, Able L, Harari PM, Iyer G, Kimple RJ, Baschnagel AM. Abstract 2929: Radiosensitization of head and neck cancer by FGFR inhibition Cancer Research. 79: 2929-2929. DOI: 10.1158/1538-7445.Am2019-2929  0.01
2019 Miller M, Fisher M, Senthilkumar G, Kaushik S, Able L, Brennan S, Iyer G, Kimple R, Baschnagel AM. Abstract 2924: Evaluation of the pan-FGFR inhibitor AZD4547 with radiation in non-small cell lung cancer Cancer Research. 79: 2924-2924. DOI: 10.1158/1538-7445.Am2019-2924  0.01
2018 Brand TM, Iida M, Stein AP, Corrigan KL, Braverman CM, Coan JP, Pearson HE, Bahrar H, Fowler TL, Bednarz BP, Saha S, Yang D, Gill PS, Lingen MW, Saloura V, ... ... Kimple RJ, et al. Correction: AXL Is a Logical Molecular Target in Head and Neck Squamous Cell Carcinoma. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 24: 6099. PMID 30510088 DOI: 10.1158/1078-0432.Ccr-18-3194  0.01
2018 Burr AR, Harari PM, Ko HC, Chen S, Yu M, Baschnagel AM, Kimple RJ, Witek ME. HPV impacts survival of stage IVC non-oropharyngeal HNSCC cancer patients. Otorhinolaryngology-Head and Neck Surgery. 3. PMID 30271885  0.01
2018 Jang S, Rosenberg SA, Bradley KA, Kimple RJ. In Reply to Lin and Golden. International Journal of Radiation Oncology, Biology, Physics. 102: 672. PMID 30238905 DOI: 10.1016/J.Ijrobp.2018.06.043  0.01
2018 McDaniel NK, Cummings CT, Iida M, Hulse J, Pearson HE, Vasileiadi E, Parker RE, Orbuch RA, Ondracek OJ, Welke NB, Kang GH, Davies KD, Wang X, Frye SV, Earp HS, ... ... Kimple RJ, et al. MERTK mediates intrinsic and adaptive resistance to AXL-targeting agents. Molecular Cancer Therapeutics. PMID 30093568 DOI: 10.1158/1535-7163.Mct-17-1239  0.01
2018 Blitzer GC, Rosenberg SA, Anderson BM, McCulloch TM, Wieland AM, Hartig GK, Bruce JY, Witek ME, Kimple RJ, Harari PM. Results From a Free Oral Cancer Screening Clinic at a Major Academic Health Center: 10 Years of Free Oral Cancer Screening at an Academic Medical Center. International Journal of Radiation Oncology, Biology, Physics. PMID 29980415 DOI: 10.1016/J.Ijrobp.2018.05.007  0.01
2018 Ko HC, Kimple RJ. The Resident Individual Development Plan as a Guide for Radiation Oncology Mentorship. International Journal of Radiation Oncology, Biology, Physics. 101: 786-788. PMID 29976489 DOI: 10.1016/J.Ijrobp.2018.02.153  0.01
2018 Jang S, Rosenberg SA, Hullett C, Bradley KA, Kimple RJ. Beyond 'charting outcomes' in the radiation oncology match: analysis of self-reported applicant data. Medical Education Online. 23: 1489691. PMID 29943670 DOI: 10.1016/J.Ijrobp.2018.07.1158  0.01
2018 Che Fru L, Adamson EB, Campos DD, Fain SB, Jacques SL, van der Kogel AJ, Nickel KP, Song C, Kimple RJ, Kissick MW. Corrigendum: Potential role of the glycolytic oscillator in acute hypoxia in tumors (2015 Phys. Med. Biol. 60 9215). Physics in Medicine and Biology. PMID 29873307 DOI: 10.1088/1361-6560/Aacaba  0.01
2018 Rosenberg SA, Bradley KA, Kimple RJ. In Reply to Hamstra. International Journal of Radiation Oncology, Biology, Physics. 100: 1293-1294. PMID 29722667 DOI: 10.1016/J.Ijrobp.2018.01.038  0.01
2018 Eckers JC, Swick AD, Kimple RJ. Identity Crisis - Rigor and Reproducibility in Human Cell Lines. Radiation Research. PMID 29652622 DOI: 10.1667/Rr15086.1  0.01
2018 Gan GN, Kimple RJ. Genomics Reloaded: Rise of the Expression Profiles. International Journal of Radiation Oncology, Biology, Physics. 101: 1-3. PMID 29619961 DOI: 10.1016/J.Ijrobp.2017.10.023  0.01
2018 Davidson SM, Ko HC, Harari PM, Wieland AM, Chen S, Baschnagel AM, Kimple RJ, Witek AME. Impact of HPV Status on the Prognostic Potential of the AJCC Staging System for Larynx Cancer. Otolaryngology--Head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery. 194599818766035. PMID 29611770 DOI: 10.1177/0194599818766035  0.01
2018 Jang S, Rosenberg SA, Hullet C, Bradley KA, Kimple RJ. Value of Elective Radiation Oncology Rotations: How Many Is Too Many? International Journal of Radiation Oncology, Biology, Physics. 100: 558-559. PMID 29413271 DOI: 10.1016/J.Ijrobp.2017.10.052  0.01
2018 Gallagher SJ, Rosenberg SA, Francis D, Salamat S, Howard SP, Kimple RJ. Primary intracranial leiomyosarcoma in an immunocompetent patient: Case report and review of the literature. Clinical Neurology and Neurosurgery. 165: 76-80. PMID 29324399 DOI: 10.1016/J.Clineuro.2017.12.014  0.01
2018 Redlich N, Robinson AM, Nickel KP, Stein AP, Wheeler DL, Adkins DR, Uppaluri R, Kimple RJ, Van Tine BA, Michel LS. Anti-Trop2 blockade enhances the therapeutic efficacy of ErbB3 inhibition in head and neck squamous cell carcinoma. Cell Death & Disease. 9: 5. PMID 29305574 DOI: 10.1038/S41419-017-0029-0  0.01
2018 Fisher MM, Swick AD, Nickel KP, Kimple RJ. Abstract 856: Selection of radiosensitizers based on HRAS mutation in bladder cancer Cancer Research. 78: 856-856. DOI: 10.1158/1538-7445.Am2018-856  0.01
2018 Pasch CA, Favreau PF, Yueh AE, Nickel KP, Babiarz CP, Emmerich PB, Pitera RT, Payne SN, Korkos DP, Sharick JT, Sprackling CM, Clipson L, Matkowskyj KA, Newton MA, Skala MC, ... ... Kimple RJ, et al. Abstract 5011: Patient-derived organotypic cancer spheroids (PDOCS) as predictive models for the treatment of cancer in a clinically meaningful time frame Tumor Biology. DOI: 10.1158/1538-7445.Am2018-5011  0.01
2018 Funk LC, Lee DL, Kimple RJ, Lambert PF, Weaver BA. Abstract 1846: HPV oncoproteins cause specific types of chromosomal instability in head and neck cancer Cancer Research. 78: 1846-1846. DOI: 10.1158/1538-7445.Am2018-1846  0.01
2018 McDaniel NK, Cummings CT, Brand TM, Iida M, Hulse J, Pearson HE, Orbuch RA, Ondracek OJ, Davies KD, Gill P, Wang X, Frye SV, Earp HS, Kimple RJ, Harari PM, et al. Abstract A140: MERTK mediates intrinsic and adaptive resistance to AXL-targeting agents Molecular Cancer Therapeutics. 17. DOI: 10.1158/1535-7163.Targ-17-A140  0.01
2017 Fowler TL, Fisher MM, Bailey AM, Bednarz BP, Kimple RJ. Biological characterization of a novel in vitro cell irradiator. Plos One. 12: e0189494. PMID 29232400 DOI: 10.1371/Journal.Pone.0189494  0.01
2017 Rosenberg SA, Kimple RJ. The Second Stain: A Viral Whodunnit. International Journal of Radiation Oncology, Biology, Physics. 99: 1061. PMID 29165273 DOI: 10.1016/J.Ijrobp.2017.05.027  0.01
2017 Kirsch DG, Diehn M, Kesarwala AH, Maity A, Morgan MA, Schwarz JK, Bristow R, Demaria S, Eke I, Griffin RJ, Haas-Kogan D, Higgins GS, Kimmelman AC, Kimple RJ, Lombaert IM, et al. The Future of Radiobiology. Journal of the National Cancer Institute. PMID 29126306 DOI: 10.1093/Jnci/Djx231  0.01
2017 Pearson HE, Iida M, Orbuch RA, McDaniel NK, Nickel KP, Kimple RJ, Arbiser J, Wheeler DL. Overcoming resistance to cetuximab with honokiol, a small-molecule polyphenol. Molecular Cancer Therapeutics. PMID 29054984 DOI: 10.1158/1535-7163.Mct-17-0384  0.01
2017 Ko HC, Harari PM, Chen S, Wieland AM, Yu M, Baschnagel AM, Kimple RJ, Witek ME. Survival Outcomes for Patients With T3N0M0 Squamous Cell Carcinoma of the Glottic Larynx. Jama Otolaryngology-- Head & Neck Surgery. PMID 29049434 DOI: 10.1001/Jamaoto.2017.1756  0.01
2017 Ko HC, Harari PM, Sacotte RM, Chen S, Wieland AM, Yu M, Baschnagel AM, Bruce JY, Kimple RJ, Witek ME. Prognostic implications of human papillomavirus status for patients with non-oropharyngeal head and neck squamous cell carcinomas. Journal of Cancer Research and Clinical Oncology. PMID 28752235 DOI: 10.1007/S00432-017-2481-8  0.01
2017 Prabakaran PJ, Javaid AM, Swick AD, Werner LR, Nickel KP, Sampene E, Hu R, Ong IM, Bruce JY, Hartig GK, Wieland A, Canon J, Harari PM, Kimple RJ. Radiosensitization of adenoid cystic carcinoma with MDM2 inhibition. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 28659312 DOI: 10.1158/1078-0432.Ccr-17-0969  0.01
2017 Pointer KB, Ko HC, Brower JV, Witek ME, Kimple RJ, Lloyd RV, Harari PM, Baschnagel AM. Small cell carcinoma of the head and neck: An analysis of the National Cancer Database. Oral Oncology. 69: 92-98. PMID 28559027 DOI: 10.1016/J.Oraloncology.2017.04.009  0.01
2017 Jang S, Patel PN, Kimple RJ, McCulloch TM. Clinical Outcomes and Prognostic Factors of Adenoid Cystic Carcinoma of the Head and Neck. Anticancer Research. 37: 3045-3052. PMID 28551643 DOI: 10.21873/Anticanres.11659  0.01
2017 Chiang J, Nickel K, Kimple RJ, Brace CL. Potential Mechanisms of Vascular Thrombosis after Microwave Ablation in an in Vivo Liver. Journal of Vascular and Interventional Radiology : Jvir. PMID 28456355 DOI: 10.1016/J.Jvir.2017.03.034  0.01
2017 Swick AD, Prabakaran PJ, Miller MC, Javaid AM, Fisher MM, Sampene E, Ong IM, Hu R, Iida M, Nickel KP, Bruce JY, Wheeler DL, Kimple RJ. Co-targeting mTORC and EGFR signaling as a therapeutic strategy in HNSCC. Molecular Cancer Therapeutics. PMID 28446642 DOI: 10.1200/Jco.2017.35.15_Suppl.E17509  0.01
2017 Brand TM, Iida M, Corrigan KL, Braverman CM, Coan JP, Flanigan BG, Stein AP, Salgia R, Rolff J, Kimple RJ, Wheeler DL. The receptor tyrosine kinase AXL mediates nuclear translocation of the epidermal growth factor receptor. Science Signaling. 10. PMID 28049763 DOI: 10.1126/Scisignal.Aag1064  0.01
2017 Swick AD, Stein AP, McCulloch TM, Hartig GK, Ong IM, Sampene E, Prabakaran PJ, Liu CZ, Kimple RJ. Defining the boundaries and expanding the utility of head and neck cancer patient derived xenografts. Oral Oncology. 64: 65-72. PMID 28024726 DOI: 10.1016/J.Oraloncology.2016.11.017  0.01
2017 Swick AD, Prabakaran PJ, Miller MC, Javaid AM, Fisher MM, Sampene E, Ong IM, Iida M, Wheeler DL, Nickel KP, Bruce JY, Kimple RJ. Abstract 51: Potential and challenges in co-targeting mTORC and EGFR signaling as a therapeutic strategy in HNSCC Clinical Cancer Research. 23: 51-51. DOI: 10.1158/1557-3265.Aacrahns17-51  0.01
2017 Fisher MM, Swick AD, Nickel KP, Kimple RJ. Abstract 5192: Selection of radiosensitizers based on HRAS mutation in head and neck cancer Cancer Research. 77: 5192-5192. DOI: 10.1158/1538-7445.Am2017-5192  0.01
2017 Javaid A, Swick AD, Werner L, Prabakaran P, Hu R, Nickel KP, Ong I, Sampene E, Bruce J, Hartig G, Wieland A, Canon J, Harari P, Kimple R. Abstract 5187: Potent radiosensitization of adenoid cystic carcinoma in a patient derived xenograft model using the MDM2 inhibitor AMG 232 Cancer Research. 77: 5187-5187. DOI: 10.1158/1538-7445.Am2017-5187  0.01
2017 Black NK, Iida M, Rodems TS, Brand TM, Kimple RJ, Wheeler DL. Abstract 4176: Targeting TAM family members with antibody or small molecule inhibitors enhances therapeutic modalities of HNSCC Cancer Research. 77: 4176-4176. DOI: 10.1158/1538-7445.Am2017-4176  0.01
2017 Brand TM, Iida M, Corrigan KL, Braverman CM, Coan JP, Flanigan BG, Stein AP, Salgia R, Rolff J, Kimple RJ, Wheeler DL. Abstract 3333: The receptor tyrosine kinase AXL mediates nuclear translocation of the epidermal growth factor receptor Cancer Research. 77: 3333-3333. DOI: 10.1158/1538-7445.Am2017-3333  0.01
2017 Eckers JC, Swick AD, Fowler T, Skiba J, Nickel KP, Kimple RJ. Abstract 3307: Induction of autophagy as a mechanism of therapeutic resistance in head and neck cancer Cancer Research. 77: 3307-3307. DOI: 10.1158/1538-7445.Am2017-3307  0.01
2017 Maas A, Chatterjee A, Sudmeier L, Nickel K, Kimple RJ. Abstract 1926: The effect of Beta-Catenin upon the tumor molecular biology and growth in HNSCC: role of cancer stem cells Cancer Research. 77: 1926-1926. DOI: 10.1158/1538-7445.Am2017-1926  0.01
2017 Swick AD, Prabakaran PJ, Javaid A, Miller M, Fisher M, Sampene E, Ong IM, Nickel K, Kimple RJ. Abstract 149: Co-targeting mTORC and EGFR signaling as a potential therapeutic strategy in HNSCC Cancer Research. 77: 149-149. DOI: 10.1158/1538-7445.Am2017-149  0.01
2016 Che Fru L, Adamson E, Campos D, Fain S, Jacques S, van der Kogel A, Nickel K, Song C, Kimple R, Kissick M. WE-FG-BRA-08: Potential Role of the Glycolytic Oscillator in Acute Hypoxia in Tumors. Medical Physics. 43: 3825. PMID 28048423 DOI: 10.1118/1.4957908  0.01
2016 Fisher M, Swick AD, Nickel KP, Kimple RJ. Selection of Radiosensitizers Based on HRAS Mutation in Head and Neck Cancer. International Journal of Radiation Oncology, Biology, Physics. 96: E568-E569. PMID 27675037 DOI: 10.1016/J.Ijrobp.2016.06.2051  0.01
2016 Rosenberg SA, Francis DM, Hullet CR, Morris ZS, Brower JV, Anderson BM, Bradley KA, Bassetti MF, Kimple RJ. Online patient information from radiation oncology departments is too complex for the general population. Practical Radiation Oncology. PMID 27663932 DOI: 10.1016/J.Prro.2016.07.008  0.01
2016 Brower JV, Amini A, Chen S, Hullett CR, Kimple RJ, Wojcieszynski AP, Bassetti M, Witek ME, Yu M, Harari PM, Baschnagel AM. Improved survival with dose escalated radiotherapy in Stage III non-small cell lung cancer: Analysis of the National Cancer Data Base. Annals of Oncology : Official Journal of the European Society For Medical Oncology / Esmo. PMID 27502703 DOI: 10.1093/Annonc/Mdw276  0.01
2016 Iida M, Bahrar H, Brand TM, Pearson HE, Coan JP, Orbuch RA, Flanigan BG, Swick AD, Prabakaran P, Lantto J, Horak ID, Kragh M, Salgia R, Kimple RJ, Wheeler DL. Targeting the HER family with Pan-HER effectively overcomes resistance to cetuximab. Molecular Cancer Therapeutics. PMID 27422810 DOI: 10.1016/S0959-8049(16)32810-6  0.01
2016 Eckers JC, Kimple RJ. Predictive biomarkers for prostate brachytherapy—not there yet Translational Cancer Research. 5. DOI: 10.21037/11309  0.01
2016 Patterson AV, Kimple RJ, Jackson VJ, Swick AD, Guise CP, Abbattista MR, Bull MR, Prabakaran PJ, Silva S, Sun JD, Hart CP, Pearce TE, Smaill JB. Development of biomarkers to guide the clinical development of tarloxotinib bromide, a hypoxia-activated irreversible EGFR/HER2 inhibitor. Journal of Clinical Oncology. 34. DOI: 10.1200/Jco.2016.34.15_Suppl.E17521  0.01
2016 Prabakaran PJ, Swick AD, Nickel KP, Yang DT, Werner LR, Bruce JY, Wieland A, McCulloch TM, Hartig GK, Harari PM, Kimple RJ. Patient derived adenoid cystic carcinoma xenografts to examine personalized cancer treatment approaches. Journal of Clinical Oncology. 34. DOI: 10.1200/Jco.2016.34.15_Suppl.E14080  0.01
2016 Chatterjee A, Nickel K, Kimple RJ. Abstract 3356: Characterization and enrichment of head and neck cancer stem cells suggests differences between HPV+ and HPV- subtypes of HNSCC cells Cancer Research. 76: 3356-3356. DOI: 10.1158/1538-7445.Am2016-3356  0.01
2016 Prabakaran P, Nickel KP, Yang DT, Werner LR, Bruce JY, Wieland AM, McCulloch TM, Hartig GK, Harari PM, Swick AD, Kimple RJ. Abstract 3044: Patient-derived adenoid cystic carcinoma xenografts to study molecular target modulation of tumor radiosensitivity Cancer Research. 76: 3044-3044. DOI: 10.1158/1538-7445.Am2016-3044  0.01
2016 Swick AD, Xiaojun T, Fowler T, Nickel K, Anderson RA, Kimple RJ. Abstract 2129: Induction of autophagy as a mechanism of therapeutic resistance in head and neck cancer Cancer Research. 76: 2129-2129. DOI: 10.1158/1538-7445.Am2016-2129  0.01
2016 Campos D, Peeters W, Nickel K, Burkel B, Bussink J, Kimple R, van der Kogel A, Eliceiri K, Kissick M. SU-G-TeP3-10: Radiation Induces Prompt Live-Cell Metabolic Fluxes Medical Physics. 43: 3676-3676. DOI: 10.1118/1.4957090  0.01
2015 Morris ZS, Weichert JP, Saker J, Armstrong EA, Besemer A, Bednarz B, Kimple RJ, Harari PM. Therapeutic combination of radiolabeled CLR1404 with external beam radiation in head and neck cancer model systems. Radiotherapy and Oncology : Journal of the European Society For Therapeutic Radiology and Oncology. 116: 504-9. PMID 26123834 DOI: 10.1016/J.Radonc.2015.06.015  0.01
2015 Kimple RJ, Harari PM. The prognostic value of HPV in head and neck cancer patients undergoing postoperative chemoradiotherapy. Annals of Translational Medicine. 3: S14. PMID 26046059 DOI: 10.3978/J.Issn.2305-5839.2015.01.37  0.01
2015 Kimple RJ, Sher DJ. Human papillomavirus and head and neck cancer. International Journal of Radiation Oncology, Biology, Physics. 92: 196-9. PMID 25968816 DOI: 10.1016/J.Ijrobp.2015.01.015  0.01
2015 Wojcieszynski AP, Olson AK, Rong Y, Kimple RJ, Yadav P. Acute Toxicity From Breast Cancer Radiation Using Helical Tomotherapy With a Simultaneous Integrated Boost. Technology in Cancer Research & Treatment. PMID 25780060 DOI: 10.1177/1533034615574387  0.01
2015 Rosenberg S, Francis D, Hullett C, Morris ZS, Brower J, Fisher M, Anderson BM, Bassetti MF, Kimple RJ. Is online patient information at NCI cancer centers too complex for broad general readership? Journal of Clinical Oncology. 33: 6526-6526. DOI: 10.1200/Jco.2015.33.15_Suppl.6526  0.01
2015 Wong SJ, Li L, Hess LM, Chen AY, Curran WJ, Harari PM, Kimple RJ, Murphy BA, Opincar LL, Garden AS. Utilization and outcomes of low dose versus high dose cisplatin in head and neck cancer patients receiving concurrent radiation. Journal of Clinical Oncology. 33: 6019-6019. DOI: 10.1200/Jco.2015.33.15_Suppl.6019  0.01
2015 Swick AD, Gunderson D, Smith M, Blitzer G, Stein A, Nickel KP, Kimple RJ. Abstract 3603: Molecular targeting of cetuximab resistant head and neck cancer Cancer Research. 75: 3603-3603. DOI: 10.1158/1538-7445.Am2015-3603  0.01
2015 Bailey A, Fowler T, Nickel KP, Bednarz B, Kimple RJ. Abstract 1801: Biological validation of a novel high-throughput irradiator for predictive radiation sensitivity bioassays Cancer Research. 75: 1801-1801. DOI: 10.1158/1538-7445.Am2015-1801  0.01
2015 Swick A, Prabakaran J, Fisher M, Stein A, Gunderson D, Nickel K, Kimple R. Abstract A122: Pre-clinical investigation of resistance to molecular targeted therapeutics in head and neck cancer Molecular Cancer Therapeutics. 14. DOI: 10.1158/1535-7163.Targ-15-A122  0.01
2015 Campos D, Peeters W, Nickel K, Eliceiri K, Kimple R, Kogel AVD, Kissick M. SU-C-303-02: Correlating Metabolic Response to Radiation Therapy with HIF-1alpha Expression Medical Physics. 42: 3197-3197. DOI: 10.1118/1.4923819  0.01
2015 Chiang J, Martin J, Nickel K, Kimple R, Brace C. Potential mechanisms of the heat-sink effect during microwave ablation of an in-vivo porcine liver model Journal of Vascular and Interventional Radiology. 26: S117-S118. DOI: 10.1016/J.Jvir.2014.12.318  0.01
2015 Rosenberg S, Francis D, Hullett C, Morris Z, Brower J, Anderson B, Bradley K, Bassetti M, Kimple R. Online Patient Information From Radiation Oncology Departments May Be too Complex for the General Population International Journal of Radiation Oncology*Biology*Physics. 93: E353. DOI: 10.1016/J.Ijrobp.2015.07.1447  0.01
2014 Campos D, Niles D, Adamson E, Torres A, Kissick M, Eliceiri K, Kimple R. WE-E-BRE-12: Tumor Microenvironment Dynamics Following Radiation. Medical Physics. 41: 506. PMID 28038019 DOI: 10.1118/1.4889441  0.01
2014 Fowler TL, Martin JA, Shepard AJ, Bailey AM, Nickel KP, Kimple RJ, Bednarz BP. WE-E-BRE-03: Biological Validation of a Novel High-Throughput Irradiator for Predictive Radiation Sensitivity Bioassays. Medical Physics. 41: 504. PMID 28037084 DOI: 10.1118/1.4889432  0.01
2014 Kissick M, Campos D, Adamson E, Niles D, Torres A, L CF, Kimple R, Fain S, Jacques S, van der Kogel A. MO-G-BRF-06: Radiotherapy and Prompt Oxygen Dynamics. Medical Physics. 41: 435. PMID 28036917 DOI: 10.1118/1.4889198  0.01
2014 Swick A, Kimple RJ. Wetting the whistle: neurotropic factor improves salivary function. The Journal of Clinical Investigation. 124: 3282-4. PMID 25036702 DOI: 10.1172/Jci77194  0.01
2014 Kimple RJ, Harari PM. Is radiation dose reduction the right answer for HPV-positive head and neck cancer? Oral Oncology. 50: 560-4. PMID 24134946 DOI: 10.1016/J.Oraloncology.2013.09.015  0.01
2014 Martin JA, Gunderson D, Kimple RJ. Abstract 4899: Small proline rich protein 3 (SPRR3) is a potential mediator of radiation resistance in HPV negative head and neck squamous cell carcinoma Cancer Research. 74: 4899-4899. DOI: 10.1158/1538-7445.Am2014-4899  0.01
2014 Law ADT, Blitzer GC, Smith MA, Armstrong EA, Kimple RJ. Abstract 4243: EGFR inhibition causes growth delay and induces apoptosis in HPV-positive head and neck cancer Cancer Research. 74: 4243-4243. DOI: 10.1158/1538-7445.Am2014-4243  0.01
2014 Hong J, Johannsen E, Boon Jd, Horswill M, Ahlquist P, Lambert P, Kimple R. Patterns of HPV Integration and Cancer-Associated Mutations in Head-and-Neck Cancer Patient-Derived Xenografts International Journal of Radiation Oncology*Biology*Physics. 88: 516. DOI: 10.1016/J.Ijrobp.2013.11.166  0.01
2013 Kissick M, Campos D, Kogel Avd, Kimple R. On the importance of prompt oxygen changes for hypofractionated radiation treatments. Physics in Medicine and Biology. 58. PMID 24061351 DOI: 10.1088/0031-9155/58/20/N279  0.01
2013 Fowler TL, Ludwig KD, Djavadian R, Bednarz BP, Kimple RJ. Abstract 1664: A delicate balance between radiation-induced autophagy and apoptosis in HPV-positive head and neck cancer. Cancer Research. 73: 1664-1664. DOI: 10.1158/1538-7445.Am2013-1664  0.01
2013 Fowler T, Fulkerson R, Micka J, Kimple R, Bednarz B. TH-F-105-04: Development of a Novel High-Throughput Variable Dose Rate Irradiator for in Vitro Radiobiology Research Medical Physics. 40: 552-552. DOI: 10.1118/1.4815817  0.01
2013 Campos D, Torres A, Lakshman M, Kissick M, Kimple R, Jacques S, Yue Y. SU‐E‐T‐292: In‐Vivo Blood Oxygen Measurements Via Interstitial Fiber Optic Probe and Photoacoustic Imaging Medical Physics. 40: 271-271. DOI: 10.1118/1.4814726  0.01
2012 Campos D, Yan Y, Zhao D, Kissick M, Jacques S, van der Kogel A, Kimple R. SU-E-J-196: In-Vivo Tumor Blood-Oxygen Content Measurement via Interstitial Optical Transmission Spectroscopy. Medical Physics. 39: 3698. PMID 28519036 DOI: 10.1118/1.4735037  0.01
2012 Zhao D, Campos D, Yan Y, Kimple R, Jacques S, van der Kogel A, Kissick M. SU-E-J-197: A Novel Optical Interstitial Fiber Spectroscopic System for Real-Time Tissue Micro-Vascular Hemodynamics Monitoring. Medical Physics. 39: 3698. PMID 28519022 DOI: 10.1118/1.4735038  0.01
2012 Kimple RJ, Russo S, Monjazeb A, Blackstock AW. The role of chemoradiation for patients with resectable or potentially resectable pancreatic cancer. Expert Review of Anticancer Therapy. 12: 469-80. PMID 22500684 DOI: 10.1586/Era.12.18  0.01
2011 VanderWalde NA, Ollila DW, DeMore NK, Moore DT, Kimple RJ, Kuzmiak CM, Pavic D, Sartor CI, Lian J, Jones EL. Local Recurrence Outcomes in Phase II Clinical Trial Using Single Dose Intraoperative Radiotherapy (IORT) before Surgical Excision of Early-stage Breast Cancer International Journal of Radiation Oncology Biology Physics. 81. DOI: 10.1016/J.Ijrobp.2011.06.020  0.01
2010 Kimple RJ. Strategizing the clone wars: pharmacological control of cellular sensitivity to radiation. Molecular Interventions. 10: 341-53. PMID 21263160 DOI: 10.1124/Mi.10.6.3  0.01
2010 Kimple RJ, Wallen EM, Pruthi R, Marks LB. A simple algorithm to assess patient suitability for Calypso-seed implantation for four-dimensional prostate localization. Journal of Applied Clinical Medical Physics / American College of Medical Physics. 11: 3107. PMID 20160683 DOI: 10.1120/Jacmp.V11I1.3107  0.01
2010 Kimple RJ, Grabowski S, Papez M, Collichio F, Ewend MG, Morris DE. Concurrent temozolomide and radiation, a reasonable option for elderly patients with glioblastoma multiforme? American Journal of Clinical Oncology. 33: 265-70. PMID 19823072 DOI: 10.1097/Coc.0B013E3181A76A24  0.01
2009 Morris DE, Kimple RJ. Normal tissue tolerance for high-grade gliomas: is it an issue? Seminars in Radiation Oncology. 19: 187-92. PMID 19464634 DOI: 10.1016/J.Semradonc.2009.02.007  0.01
2009 Sambade MJ, Kimple RJ, Camp T, Peters E, Livasy CA, Sartor CI, Shields JM. Abstract B73: Lapatinib‐mediated radiosensitization of EGFR+/basal breast cancer correlates withERK inhibition in vivo and requires MEK/ERK inhibition in vitro Molecular Cancer Therapeutics. 8. DOI: 10.1158/1535-7163.Targ-09-B73  0.01
2009 Kimple RJ, Sartor CI, Moore DT, Chiu WM, Esler L, Klauber-DeMore N, Ollila DW. Three Year Local Control following Single Dose Intraoperative Radiotherapy for Early Stage Breast Cancer International Journal of Radiation Oncology Biology Physics. 75. DOI: 10.1016/J.Ijrobp.2009.07.438  0.01
2009 Tracton G, Tang X, Kimple R, Harris S, Foskey M, Chang S, Chaney E, Pizer S, Deschene K. Clinical Evaluation of M-Rep Automatic Segmentation Tool on Prostate in CT International Journal of Radiation Oncology*Biology*Physics. 75: S596. DOI: 10.1016/J.Ijrobp.2009.07.1363  0.01
2008 Sartor CI, Kimple RJ, Kuzmiak CM, Pavic D, Lian J, Chang XS, Moore DT, Phipps RF, Esler L, Klauber-Demore N, Ollila DW. Cosmetic outcomes following single-dose intraoperative radiotherapy for early stage breast cancer. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 26: 624. PMID 27949148 DOI: 10.1200/Jco.2008.26.15_Suppl.624  0.01
2008 Kimple R, Vaseva A, Cox A, Sartor C. Pancreatic Cancer Radiosensitization by Nelfinavir International Journal of Radiation Oncology*Biology*Physics. 72: S63-S64. DOI: 10.1016/J.Ijrobp.2008.06.908  0.01
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