| Year |
Citation |
Score |
| 2024 |
Van HT, Xie G, Dong P, Liu Z, Ge K. KMT2 Family of H3K4 Methyltransferases: Enzymatic Activity-dependent and -independent Functions. Journal of Molecular Biology. 168453. PMID 38266981 DOI: 10.1016/j.jmb.2024.168453 |
0.318 |
|
| 2023 |
Ko EK, Anderson A, D'souza C, Zou J, Huang S, Cho S, Alawi F, Prouty S, Lee V, Yoon S, Krick K, Horiuchi Y, Ge K, Seykora JT, Capell BC. Disruption of H3K36 methylation provokes cellular plasticity to drive aberrant glandular formation and squamous carcinogenesis. Developmental Cell. PMID 38198888 DOI: 10.1016/j.devcel.2023.12.007 |
0.34 |
|
| 2023 |
Musa RE, Lester KL, Quickstad GA, Vardabasso S, Shumate TV, Salcido RT, Ge K, Shpargel KB. BRD4 binds to active cranial neural crest enhancers to regulate RUNX2 activity during osteoblast differentiation. Development (Cambridge, England). PMID 38063851 DOI: 10.1242/dev.202110 |
0.306 |
|
| 2021 |
Jang Y, Park YK, Lee JE, Wan D, Tran N, Gavrilova O, Ge K. MED1 is a lipogenesis coactivator required for postnatal adipose expansion. Genes & Development. PMID 33888555 DOI: 10.1101/gad.347583.120 |
0.301 |
|
| 2021 |
Park YK, Lee JE, Yan Z, McKernan K, O'Haren T, Wang W, Peng W, Ge K. Interplay of BAF and MLL4 promotes cell type-specific enhancer activation. Nature Communications. 12: 1630. PMID 33712604 DOI: 10.1038/s41467-021-21893-y |
0.345 |
|
| 2020 |
Tran N, Broun A, Ge K. Lysine demethylase KDM6A in differentiation, development and cancer. Molecular and Cellular Biology. PMID 32817139 DOI: 10.1128/Mcb.00341-20 |
0.478 |
|
| 2020 |
Pacelli C, Adipietro I, Malerba N, Squeo GM, Piccoli C, Amoresano A, Pinto G, Pucci P, Lee JE, Ge K, Capitanio N, Merla G. Loss of Function of the Gene Encoding the Histone Methyltransferase KMT2D Leads to Deregulation of Mitochondrial Respiration. Cells. 9. PMID 32668765 DOI: 10.3390/Cells9071685 |
0.321 |
|
| 2020 |
Lee JE, Cho YW, Deng CX, Ge K. MLL3/MLL4-associated PAGR1 Regulates Adipogenesis by Controlling Induction of C/EBPβ and C/EBPδ. Molecular and Cellular Biology. PMID 32601106 DOI: 10.1128/Mcb.00209-20 |
0.329 |
|
| 2020 |
Liu L, Ding C, Fu T, Feng Z, Lee JE, Xiao L, Xu Z, Yin Y, Guo Q, Sun Z, Sun W, Mao Y, Yang L, Zhou Z, Zhou D, ... ... Ge K, et al. Histone methyltransferase MLL4 controls myofiber identity and muscle performance through MEF2 interaction. The Journal of Clinical Investigation. PMID 32544095 DOI: 10.1172/Jci136155 |
0.311 |
|
| 2020 |
Shpargel KB, Mangini CL, Xie G, Ge K, Magnuson T. The KMT2D Kabuki syndrome histone methylase controls neural crest cell differentiation and facial morphology. Development (Cambridge, England). PMID 32541010 DOI: 10.1242/Dev.187997 |
0.36 |
|
| 2020 |
Wu SY, Lee CF, Lai HT, Yu CT, Lee JE, Zuo H, Tsai SY, Tsai MJ, Ge K, Wan Y, Chiang CM. Opposing Functions of BRD4 Isoforms in Breast Cancer. Molecular Cell. PMID 32446320 DOI: 10.1016/J.Molcel.2020.04.034 |
0.411 |
|
| 2020 |
Kwon M, Park K, Hyun K, Lee JH, Zhou L, Cho YW, Ge K, Skalnik DG, Muir TW, Kim J. H2B ubiquitylation enhances H3K4 methylation activities of human KMT2 family complexes. Nucleic Acids Research. PMID 32365172 DOI: 10.1093/Nar/Gkaa317 |
0.37 |
|
| 2020 |
Kang JG, Lago CU, Lee JE, Park JH, Donnelly MP, Starost MF, Liu C, Kwon J, Noguchi AC, Ge K, Wang PY, Hwang PM. A Mouse Homolog of a Human TP53 Germline Mutation Reveals a Lipolytic Activity of p53. Cell Reports. 30: 783-792.e5. PMID 31968253 DOI: 10.1016/J.Celrep.2019.12.074 |
0.344 |
|
| 2020 |
Jang Y, Tran N, Ge K. SUN-589 MED1 Is a Lipogenesis Coactivator Required for Postnatal Adipose Tissue Expansion Journal of the Endocrine Society. 4. DOI: 10.1210/Jendso/Bvaa046.955 |
0.355 |
|
| 2019 |
Zhang Y, Jang Y, Lee JE, Ahn J, Xu L, Holden MR, Cornett EM, Krajewski K, Klein BJ, Wang SP, Dou Y, Roeder RG, Strahl BD, Rothbart SB, Shi X, ... Ge K, et al. Selective binding of the PHD6 finger of MLL4 to histone H4K16ac links MLL4 and MOF. Nature Communications. 10: 2314. PMID 31127101 DOI: 10.1038/S41467-019-10324-8 |
0.391 |
|
| 2019 |
Zhu M, Lu T, Jia Y, Luo X, Gopal P, Li L, Odewole M, Renteria V, Singal AG, Jang Y, Ge K, Wang SC, Sorouri M, Parekh JR, MacConmara MP, et al. Somatic Mutations Increase Hepatic Clonal Fitness and Regeneration in Chronic Liver Disease. Cell. PMID 30955891 DOI: 10.1016/J.Cell.2019.03.026 |
0.323 |
|
| 2019 |
Lee JE, Schmidt H, Lai B, Ge K. Transcriptional and Epigenomic Regulation of Adipogenesis. Molecular and Cellular Biology. PMID 30936246 DOI: 10.1128/Mcb.00601-18 |
0.405 |
|
| 2018 |
Jang Y, Broun A, Wang C, Park YK, Zhuang L, Lee JE, Froimchuk E, Liu C, Ge K. H3.3K4M destabilizes enhancer H3K4 methyltransferases MLL3/MLL4 and impairs adipose tissue development. Nucleic Acids Research. PMID 30335158 DOI: 10.1093/Nar/Gky982 |
0.388 |
|
| 2018 |
Das P, Veazey KJ, Van HT, Kaushik S, Lin K, Lu Y, Ishii M, Kikuta J, Ge K, Nussenzweig A, Santos MA. Histone methylation regulator PTIP is required to maintain normal and leukemic bone marrow niches. Proceedings of the National Academy of Sciences of the United States of America. PMID 30297393 DOI: 10.1073/Pnas.1806019115 |
0.393 |
|
| 2018 |
Sun Y, Zhou B, Mao F, Xu J, Miao H, Zou Z, Phuc Khoa LT, Jang Y, Cai S, Witkin M, Koche R, Ge K, Dressler GR, Levine RL, Armstrong SA, et al. HOXA9 Reprograms the Enhancer Landscape to Promote Leukemogenesis. Cancer Cell. PMID 30270123 DOI: 10.1016/J.Ccell.2018.08.018 |
0.434 |
|
| 2018 |
Seok S, Kim YC, Byun S, Choi S, Xiao Z, Iwamori N, Zhang Y, Wang C, Ma J, Ge K, Kemper B, Kemper JK. Fasting-induced JMJD3 histone demethylase epigenetically activates mitochondrial fatty acid β-oxidation. The Journal of Clinical Investigation. PMID 29911994 DOI: 10.1172/Jci97736 |
0.376 |
|
| 2018 |
Zhuang L, Jang Y, Park YK, Lee JE, Jain S, Froimchuk E, Broun A, Liu C, Gavrilova O, Ge K. Depletion of Nsd2-mediated histone H3K36 methylation impairs adipose tissue development and function. Nature Communications. 9: 1796. PMID 29728617 DOI: 10.1038/S41467-018-04127-6 |
0.39 |
|
| 2018 |
Wu Q, Tian Y, Zhang J, Tong X, Huang H, Li S, Zhao H, Tang Y, Yuan C, Wang K, Fang Z, Gao L, Hu X, Li F, Qin Z, ... ... Ge K, et al. In vivo CRISPR screening unveils histone demethylase UTX as an important epigenetic regulator in lung tumorigenesis. Proceedings of the National Academy of Sciences of the United States of America. PMID 29632194 DOI: 10.1073/Pnas.1716589115 |
0.339 |
|
| 2018 |
Yan J, Chen SA, Local A, Liu T, Qiu Y, Dorighi KM, Preissl S, Rivera CM, Wang C, Ye Z, Ge K, Hu M, Wysocka J, Ren B. Histone H3 lysine 4 monomethylation modulates long-range chromatin interactions at enhancers. Cell Research. PMID 29313530 DOI: 10.1038/cr.2018.1 |
0.33 |
|
| 2018 |
Zhang Z, Christin JR, Wang C, Ge K, Oktay M, Guo W. Abstract B47: Validation of novel breast cancer drivers using mammary stem cell-based somatic mouse models Molecular Cancer Research. 16. DOI: 10.1158/1557-3125.Advbc17-B47 |
0.365 |
|
| 2017 |
Lee JE, Park YK, Park S, Jang Y, Waring N, Dey A, Ozato K, Lai B, Peng W, Ge K. Brd4 binds to active enhancers to control cell identity gene induction in adipogenesis and myogenesis. Nature Communications. 8: 2217. PMID 29263365 DOI: 10.1038/S41467-017-02403-5 |
0.471 |
|
| 2017 |
Local A, Huang H, Albuquerque CP, Singh N, Lee AY, Wang W, Wang C, Hsia JE, Shiau AK, Ge K, Corbett KD, Wang D, Zhou H, Ren B. Identification of H3K4me1-associated proteins at mammalian enhancers. Nature Genetics. PMID 29255264 DOI: 10.1038/S41588-017-0015-6 |
0.469 |
|
| 2017 |
Katz LS, Xu S, Ge K, Scott DK, Gershengorn MC. T3 AND GLUCOSE COORDINATELY STIMULATE ChREBP-MEDIATED UCP1 EXPRESSION IN BROWN ADIPOCYTES FROM MALE MICE. Endocrinology. PMID 29077876 DOI: 10.1210/En.2017-00579 |
0.316 |
|
| 2017 |
Shpargel KB, Starmer J, Wang C, Ge K, Magnuson T. UTX-guided neural crest function underlies craniofacial features of Kabuki syndrome. Proceedings of the National Academy of Sciences of the United States of America. 114: E9046-E9055. PMID 29073101 DOI: 10.1073/Pnas.1705011114 |
0.417 |
|
| 2017 |
Placek K, Hu G, Cui K, Zhang D, Ding Y, Lee JE, Jang Y, Wang C, Konkel JE, Song J, Liu C, Ge K, Chen W, Zhao K. MLL4 prepares the enhancer landscape for Foxp3 induction via chromatin looping. Nature Immunology. PMID 28759003 DOI: 10.1038/Ni.3812 |
0.447 |
|
| 2017 |
Froimchuk E, Jang Y, Ge K. Histone H3 lysine 4 methyltransferase KMT2D. Gene. PMID 28669924 DOI: 10.1016/J.Gene.2017.06.056 |
0.495 |
|
| 2017 |
Northrup D, Yagi R, Cui K, Proctor WR, Wang C, Placek K, Pohl LR, Wang R, Ge K, Zhu J, Zhao K. Histone demethylases UTX and JMJD3 are required for NKT cell development in mice. Cell & Bioscience. 7: 25. PMID 28529687 DOI: 10.1186/S13578-017-0152-8 |
0.401 |
|
| 2017 |
Lai B, Lee JE, Jang Y, Wang L, Peng W, Ge K. MLL3/MLL4 are required for CBP/p300 binding on enhancers and super-enhancer formation in brown adipogenesis. Nucleic Acids Research. PMID 28398509 DOI: 10.1093/Nar/Gkx234 |
0.431 |
|
| 2017 |
Chaudhuri AR, Callen E, Ding X, Gogola E, Duarte AA, Lee J, Wong N, Lafarga V, Calvo JA, Panzarino NJ, John S, Day A, Crespo AV, Shen B, Starnes LM, ... ... Ge K, et al. Abstract IA09: Replication fork stability confers chemoresistance in BRCA-deficient cells Molecular Cancer Research. 15. DOI: 10.1158/1557-3125.Dnarepair16-Ia09 |
0.359 |
|
| 2016 |
Jang Y, Wang C, Zhuang L, Liu C, Ge K. H3K4 methyltransferase activity is required for MLL4 protein stability. Journal of Molecular Biology. PMID 28013028 DOI: 10.1016/J.Jmb.2016.12.016 |
0.47 |
|
| 2016 |
Park YK, Ge K. Glucocorticoid receptor accelerates, but is dispensable for, adipogenesis. Molecular and Cellular Biology. PMID 27777311 DOI: 10.1128/Mcb.00260-16 |
0.407 |
|
| 2016 |
Park YK, Wang L, Giampietro A, Lai B, Lee JE, Ge K. Distinct roles of transcription factors KLF4, Krox20 and PPARγ in adipogenesis. Molecular and Cellular Biology. PMID 27777310 DOI: 10.1128/Mcb.00554-16 |
0.372 |
|
| 2016 |
Wang C, Lee JE, Lai B, Macfarlan TS, Xu S, Zhuang L, Liu C, Peng W, Ge K. Enhancer priming by H3K4 methyltransferase MLL4 controls cell fate transition. Proceedings of the National Academy of Sciences of the United States of America. PMID 27698142 DOI: 10.1073/Pnas.1606857113 |
0.469 |
|
| 2016 |
Zhang Z, Christin JR, Wang C, Ge K, Oktay MH, Guo W. Mammary-Stem-Cell-Based Somatic Mouse Models Reveal Breast Cancer Drivers Causing Cell Fate Dysregulation. Cell Reports. 16: 3146-56. PMID 27653681 DOI: 10.1016/J.Celrep.2016.08.048 |
0.385 |
|
| 2016 |
Ray Chaudhuri A, Callen E, Ding X, Gogola E, Duarte AA, Lee JE, Wong N, Lafarga V, Calvo JA, Panzarino NJ, John S, Day A, Crespo AV, Shen B, Starnes LM, ... ... Ge K, et al. Replication fork stability confers chemoresistance in BRCA-deficient cells. Nature. 535: 382-7. PMID 27443740 DOI: 10.1038/Nature18325 |
0.344 |
|
| 2016 |
Yoo KH, Oh S, Kang K, Wang C, Robinson GW, Ge K, Hennighausen L. The histone demethylase KDM6A controls the mammary luminal lineage through enzyme-independent mechanisms. Molecular and Cellular Biology. PMID 27215382 DOI: 10.1128/Mcb.00089-16 |
0.452 |
|
| 2016 |
Faralli H, Wang C, Nakka K, Benyoucef A, Sebastian S, Zhuang L, Chu A, Palii CG, Liu C, Camellato B, Brand M, Ge K, Dilworth FJ. UTX demethylase activity is required for satellite cell-mediated muscle regeneration. The Journal of Clinical Investigation. PMID 26999603 DOI: 10.1172/Jci83239 |
0.393 |
|
| 2016 |
Benyoucef A, Palii CG, Wang C, Porter CJ, Chu A, Dai F, Tremblay V, Rakopoulos P, Singh K, Huang S, Pflumio F, Hébert J, Couture JF, Perkins TJ, Ge K, et al. UTX inhibition as selective epigenetic therapy against TAL1-driven T-cell acute lymphoblastic leukemia. Genes & Development. 30: 508-21. PMID 26944678 DOI: 10.1101/Gad.276790.115 |
0.368 |
|
| 2016 |
Ang SY, Uebersohn A, Spencer CI, Huang Y, Lee JE, Ge K, Bruneau BG. KMT2D regulates specific programs in heart development via histone H3 lysine 4 di-methylation. Development (Cambridge, England). 143: 810-21. PMID 26932671 DOI: 10.1242/Dev.132688 |
0.41 |
|
| 2016 |
Starnes LM, Su D, Pikkupeura LM, Weinert BT, Santos MA, Mund A, Soria R, Cho YW, Pozdnyakova I, Kubec Højfeldt M, Vala A, Yang W, López-Méndez B, Lee JE, Peng W, ... ... Ge K, et al. A PTIP-PA1 subcomplex promotes transcription for IgH class switching independently from the associated MLL3/MLL4 methyltransferase complex. Genes & Development. PMID 26744420 DOI: 10.1101/Gad.268797.115 |
0.397 |
|
| 2016 |
Zhang J, Dominguez-Sola D, Hussein S, Lee J, Holmes AB, Bansal M, Vlasevska S, Mo T, Tang H, Basso K, Ge K, Dalla-Favera R, Pasqualucci L. Abstract B25: Disruption of KMT2D-dependent histone methylation perturbs GC B cell development and cooperates with BCL2 deregulation in lymphomagenesis Cancer Research. 76. DOI: 10.1158/1538-7445.Chromepi15-B25 |
0.447 |
|
| 2015 |
Zhang J, Dominguez-Sola D, Hussein S, Lee JE, Holmes AB, Bansal M, Vlasevska S, Mo T, Tang H, Basso K, Ge K, Dalla-Favera R, Pasqualucci L. Disruption of KMT2D perturbs germinal center B cell development and promotes lymphomagenesis. Nature Medicine. PMID 26366712 DOI: 10.1038/Nm.3940 |
0.409 |
|
| 2015 |
Ortega-Molina A, Boss IW, Canela A, Pan H, Jiang Y, Zhao C, Jiang M, Hu D, Agirre X, Niesvizky I, Lee JE, Chen HT, Ennishi D, Scott DW, Mottok A, ... ... Ge K, et al. The histone lysine methyltransferase KMT2D sustains a gene expression program that represses B cell lymphoma development. Nature Medicine. PMID 26366710 DOI: 10.1038/Nm.3943 |
0.453 |
|
| 2014 |
Shi X, Zhang Z, Zhan X, Cao M, Satoh T, Akira S, Shpargel K, Magnuson T, Li Q, Wang R, Wang C, Ge K, Wu J. An epigenetic switch induced by Shh signalling regulates gene activation during development and medulloblastoma growth. Nature Communications. 5: 5425. PMID 25370275 DOI: 10.1038/Ncomms6425 |
0.426 |
|
| 2014 |
Jin Q, Zhuang L, Lai B, Wang C, Li W, Dolan B, Lu Y, Wang Z, Zhao K, Peng W, Dent SY, Ge K. Gcn5 and PCAF negatively regulate interferon-β production through HAT-independent inhibition of TBK1. Embo Reports. 15: 1192-201. PMID 25269644 DOI: 10.15252/Embr.201438990 |
0.304 |
|
| 2014 |
Santos MA, Faryabi RB, Ergen AV, Day AM, Malhowski A, Canela A, Onozawa M, Lee JE, Callen E, Gutierrez-Martinez P, Chen HT, Wong N, Finkel N, Deshpande A, Sharrow S, ... ... Ge K, et al. DNA-damage-induced differentiation of leukaemic cells as an anti-cancer barrier. Nature. 514: 107-11. PMID 25079327 DOI: 10.1038/Nature13483 |
0.411 |
|
| 2014 |
Jin Q, Wang C, Kuang X, Feng X, Sartorelli V, Ying H, Ge K, Dent SY. Gcn5 and PCAF regulate PPARγ and Prdm16 expression to facilitate brown adipogenesis. Molecular and Cellular Biology. 34: 3746-53. PMID 25071153 DOI: 10.1128/Mcb.00622-14 |
0.427 |
|
| 2014 |
Lee JE, Ge K. Transcriptional and epigenetic regulation of PPARγ expression during adipogenesis. Cell & Bioscience. 4: 29. PMID 24904744 DOI: 10.1186/2045-3701-4-29 |
0.406 |
|
| 2014 |
Xu S, Grullon S, Ge K, Peng W. Spatial clustering for identification of ChIP-enriched regions (SICER) to map regions of histone methylation patterns in embryonic stem cells. Methods in Molecular Biology (Clifton, N.J.). 1150: 97-111. PMID 24743992 DOI: 10.1007/978-1-4939-0512-6_5 |
0.343 |
|
| 2014 |
Kumar A, Lualdi M, Loncarek J, Cho YW, Lee JE, Ge K, Kuehn MR. Loss of function of mouse Pax-Interacting Protein 1-associated glutamate rich protein 1a (Pagr1a) leads to reduced Bmp2 expression and defects in chorion and amnion development. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 243: 937-47. PMID 24633704 DOI: 10.1002/Dvdy.24125 |
0.41 |
|
| 2013 |
Lee JE, Wang C, Xu S, Cho YW, Wang L, Feng X, Baldridge A, Sartorelli V, Zhuang L, Peng W, Ge K. H3K4 mono- and di-methyltransferase MLL4 is required for enhancer activation during cell differentiation. Elife. 2: e01503. PMID 24368734 DOI: 10.7554/Elife.01503 |
0.48 |
|
| 2013 |
Park JH, Kang HJ, Kang SI, Lee JE, Hur J, Ge K, Mueller E, Li H, Lee BC, Lee SB. A multifunctional protein, EWS, is essential for early brown fat lineage determination. Developmental Cell. 26: 393-404. PMID 23987512 DOI: 10.1016/J.Devcel.2013.07.002 |
0.371 |
|
| 2013 |
Wang AH, Zare H, Mousavi K, Wang C, Moravec CE, Sirotkin HI, Ge K, Gutierrez-Cruz G, Sartorelli V. The histone chaperone Spt6 coordinates histone H3K27 demethylation and myogenesis. The Embo Journal. 32: 1075-86. PMID 23503590 DOI: 10.1038/Emboj.2013.54 |
0.478 |
|
| 2013 |
Hu G, Cui K, Northrup D, Liu C, Wang C, Tang Q, Ge K, Levens D, Crane-Robinson C, Zhao K. H2A.Z facilitates access of active and repressive complexes to chromatin in embryonic stem cell self-renewal and differentiation. Cell Stem Cell. 12: 180-92. PMID 23260488 DOI: 10.1016/J.Stem.2012.11.003 |
0.401 |
|
| 2013 |
Wang L, Xu S, Lee JE, Baldridge A, Grullon S, Peng W, Ge K. Histone H3K9 methyltransferase G9a represses PPARγ expression and adipogenesis. The Embo Journal. 32: 45-59. PMID 23178591 DOI: 10.1038/Emboj.2012.306 |
0.38 |
|
| 2013 |
Lee J, Wang C, Xu S, Cho Y, Wang L, Feng X, Baldridge A, Sartorelli V, Zhuang L, Peng W, Ge K. Author response: H3K4 mono- and di-methyltransferase MLL4 is required for enhancer activation during cell differentiation Elife. DOI: 10.7554/Elife.01503.027 |
0.361 |
|
| 2012 |
Callen E, Faryabi RB, Luckey M, Hao B, Daniel JA, Yang W, Sun HW, Dressler G, Peng W, Chi H, Ge K, Krangel MS, Park JH, Nussenzweig A. The DNA Damage- and Transcription-Associated Protein Paxip1 Controls Thymocyte Development and Emigration Immunity. 37: 971-985. PMID 23159437 DOI: 10.1016/J.Immuni.2012.10.007 |
0.415 |
|
| 2012 |
Guo C, Chang CC, Wortham M, Chen LH, Kernagis DN, Qin X, Cho YW, Chi JT, Grant GA, McLendon RE, Yan H, Ge K, Papadopoulos N, Bigner DD, He Y. Global identification of MLL2-targeted loci reveals MLL2's role in diverse signaling pathways. Proceedings of the National Academy of Sciences of the United States of America. 109: 17603-8. PMID 23045699 DOI: 10.1073/Pnas.1208807109 |
0.427 |
|
| 2012 |
Wang C, Lee JE, Cho YW, Xiao Y, Jin Q, Liu C, Ge K. UTX regulates mesoderm differentiation of embryonic stem cells independent of H3K27 demethylase activity. Proceedings of the National Academy of Sciences of the United States of America. 109: 15324-9. PMID 22949634 DOI: 10.1073/Pnas.1204166109 |
0.454 |
|
| 2012 |
Ge K. Epigenetic regulation of adipogenesis by histone methylation. Biochimica Et Biophysica Acta. 1819: 727-32. PMID 22240386 DOI: 10.1016/J.Bbagrm.2011.12.008 |
0.423 |
|
| 2012 |
Cho YW, Hong S, Ge K. Affinity purification of MLL3/MLL4 histone H3K4 methyltransferase complex. Methods in Molecular Biology (Clifton, N.J.). 809: 465-72. PMID 22113294 DOI: 10.1007/978-1-61779-376-9_30 |
0.391 |
|
| 2012 |
Wang C, Liu Z, Woo CW, Li Z, Wang L, Wei JS, Marquez VE, Bates SE, Jin Q, Khan J, Ge K, Thiele CJ. EZH2 Mediates epigenetic silencing of neuroblastoma suppressor genes CASZ1, CLU, RUNX3, and NGFR. Cancer Research. 72: 315-24. PMID 22068036 DOI: 10.1158/0008-5472.Can-11-0961 |
0.478 |
|
| 2011 |
Jin Q, Yu LR, Wang L, Zhang Z, Kasper LH, Lee JE, Wang C, Brindle PK, Dent SY, Ge K. Distinct roles of GCN5/PCAF-mediated H3K9ac and CBP/p300-mediated H3K18/27ac in nuclear receptor transactivation. The Embo Journal. 30: 249-62. PMID 21131905 DOI: 10.1038/Emboj.2010.318 |
0.431 |
|
| 2010 |
Daniel JA, Santos MA, Wang Z, Zang C, Schwab KR, Jankovic M, Filsuf D, Chen HT, Gazumyan A, Yamane A, Cho YW, Sun HW, Ge K, Peng W, Nussenzweig MC, et al. PTIP promotes chromatin changes critical for immunoglobulin class switch recombination Science. 329: 917-923. PMID 20671152 DOI: 10.1126/Science.1187942 |
0.39 |
|
| 2010 |
Wang L, Jin Q, Lee JE, Su IH, Ge K. Histone H3K27 methyltransferase Ezh2 represses Wnt genes to facilitate adipogenesis. Proceedings of the National Academy of Sciences of the United States of America. 107: 7317-22. PMID 20368440 DOI: 10.1073/Pnas.1000031107 |
0.434 |
|
| 2010 |
Seenundun S, Rampalli S, Liu QC, Aziz A, Palii C, Hong S, Blais A, Brand M, Ge K, Dilworth FJ. UTX mediates demethylation of H3K27me3 at muscle-specific genes during myogenesis. The Embo Journal. 29: 1401-11. PMID 20300060 DOI: 10.1038/Emboj.2010.37 |
0.422 |
|
| 2010 |
Mishra A, Zhu XG, Ge K, Cheng SY. Adipogenesis is differentially impaired by thyroid hormone receptor mutant isoforms. Journal of Molecular Endocrinology. 44: 247-55. PMID 20080985 DOI: 10.1677/Jme-09-0137 |
0.396 |
|
| 2010 |
Wang C, Woo C, Liu Z, Wei J, Song Y, Wang L, Khan J, Ge K, Thiele CJ. Abstract 4880: CASZ1, a neuroblastoma tumor suppressor gene, is epigenetically silenced by EZH2 Cancer Research. 70: 4880-4880. DOI: 10.1158/1538-7445.Am10-4880 |
0.467 |
|
| 2009 |
Wang P, Lin C, Smith ER, Guo H, Sanderson BW, Wu M, Gogol M, Alexander T, Seidel C, Wiedemann LM, Ge K, Krumlauf R, Shilatifard A. Global analysis of H3K4 methylation defines MLL family member targets and points to a role for MLL1-mediated H3K4 methylation in the regulation of transcriptional initiation by RNA polymerase II. Molecular and Cellular Biology. 29: 6074-85. PMID 19703992 DOI: 10.1128/Mcb.00924-09 |
0.419 |
|
| 2009 |
Cho YW, Hong S, Jin Q, Wang L, Lee JE, Gavrilova O, Ge K. Histone methylation regulator PTIP is required for PPARgamma and C/EBPalpha expression and adipogenesis. Cell Metabolism. 10: 27-39. PMID 19583951 DOI: 10.1016/J.Cmet.2009.05.010 |
0.387 |
|
| 2009 |
Gong Z, Cho YW, Kim JE, Ge K, Chen J. Accumulation of Pax2 transactivation domain interaction protein (PTIP) at sites of DNA breaks via RNF8-dependent pathway is required for cell survival after DNA damage. The Journal of Biological Chemistry. 284: 7284-93. PMID 19124460 DOI: 10.1074/Jbc.M809158200 |
0.311 |
|
| 2008 |
Ge K, Cho YW, Guo H, Hong TB, Guermah M, Ito M, Yu H, Kalkum M, Roeder RG. Alternative mechanisms by which mediator subunit MED1/TRAP220 regulates peroxisome proliferator-activated receptor gamma-stimulated adipogenesis and target gene expression. Molecular and Cellular Biology. 28: 1081-91. PMID 18039840 DOI: 10.1128/Mcb.00967-07 |
0.421 |
|
| 2007 |
Rampalli S, Li L, Mak E, Ge K, Brand M, Tapscott SJ, Dilworth FJ. p38 MAPK signaling regulates recruitment of Ash2L-containing methyltransferase complexes to specific genes during differentiation. Nature Structural & Molecular Biology. 14: 1150-6. PMID 18026121 DOI: 10.1038/Nsmb1316 |
0.45 |
|
| 2007 |
Hong S, Cho YW, Yu LR, Yu H, Veenstra TD, Ge K. Identification of JmjC domain-containing UTX and JMJD3 as histone H3 lysine 27 demethylases. Proceedings of the National Academy of Sciences of the United States of America. 104: 18439-44. PMID 18003914 DOI: 10.1073/Pnas.0707292104 |
0.378 |
|
| 2007 |
Cho YW, Hong T, Hong S, Guo H, Yu H, Kim D, Guszczynski T, Dressler GR, Copeland TD, Kalkum M, Ge K. PTIP associates with MLL3- and MLL4-containing histone H3 lysine 4 methyltransferase complex. The Journal of Biological Chemistry. 282: 20395-406. PMID 17500065 DOI: 10.1074/Jbc.M701574200 |
0.402 |
|
| 2005 |
Park SW, Li G, Lin YP, Barrero MJ, Ge K, Roeder RG, Wei LN. Thyroid hormone-induced juxtaposition of regulatory elements/factors and chromatin remodeling of Crabp1 dependent on MED1/TRAP220. Molecular Cell. 19: 643-53. PMID 16137621 DOI: 10.1016/J.Molcel.2005.08.008 |
0.383 |
|
| 2005 |
Jia Y, Guo GL, Surapureddi S, Sarkar J, Qi C, Guo D, Xia J, Kashireddi P, Yu S, Cho YW, Rao MS, Kemper B, Ge K, Gonzalez FJ, Reddy JK. Transcription coactivator peroxisome proliferator-activated receptor-binding protein/mediator 1 deficiency abrogates acetaminophen hepatotoxicity. Proceedings of the National Academy of Sciences of the United States of America. 102: 12531-6. PMID 16109766 DOI: 10.1073/Pnas.0506000102 |
0.365 |
|
| 2004 |
Wang S, Ge K, Roeder RG, Hankinson O. Role of mediator in transcriptional activation by the aryl hydrocarbon receptor. The Journal of Biological Chemistry. 279: 13593-600. PMID 14729673 DOI: 10.1074/Jbc.M312274200 |
0.406 |
|
| 2003 |
Guermah M, Ge K, Chiang CM, Roeder RG. The TBN protein, which is essential for early embryonic mouse development, is an inducible TAFII implicated in adipogenesis. Molecular Cell. 12: 991-1001. PMID 14580349 DOI: 10.1016/S1097-2765(03)00396-4 |
0.43 |
|
| 2003 |
Muller AJ, Baker JF, DuHadaway JB, Ge K, Farmer G, Donover PS, Meade R, Reid C, Grzanna R, Roach AH, Shah N, Soler AP, Prendergast GC. Targeted disruption of the murine Bin1/Amphiphysin II gene does not disable endocytosis but results in embryonic cardiomyopathy with aberrant myofibril formation. Molecular and Cellular Biology. 23: 4295-306. PMID 12773571 DOI: 10.1128/Mcb.23.12.4295-4306.2003 |
0.575 |
|
| 2002 |
Li P, Yu X, Ge K, Melamed J, Roeder RG, Wang Z. Heterogeneous expression and functions of androgen receptor co-factors in primary prostate cancer. The American Journal of Pathology. 161: 1467-74. PMID 12368219 DOI: 10.1016/S0002-9440(10)64422-7 |
0.341 |
|
| 2002 |
Mueller E, Drori S, Aiyer A, Yie J, Sarraf P, Chen H, Hauser S, Rosen ED, Ge K, Roeder RG, Spiegelman BM. Genetic analysis of adipogenesis through peroxisome proliferator-activated receptor gamma isoforms. The Journal of Biological Chemistry. 277: 41925-30. PMID 12200443 DOI: 10.1074/Jbc.M206950200 |
0.379 |
|
| 2002 |
Ge K, Guermah M, Yuan CX, Ito M, Wallberg AE, Spiegelman BM, Roeder RG. Transcription coactivator TRAP220 is required for PPARγ2-stimulated adipogenesis Nature. 417: 563-567. PMID 12037571 DOI: 10.1038/417563A |
0.34 |
|
| 2000 |
Elliott K, Ge K, Du W, Prendergast GC. The c-Myc-interacting adaptor protein Bin1 activates a caspase-independent cell death program. Oncogene. 19: 4669-84. PMID 11032017 DOI: 10.1038/Sj.Onc.1203681 |
0.589 |
|
| 2000 |
Ge K, Prendergast GC. Bin2, a functionally nonredundant member of the BAR adaptor gene family. Genomics. 67: 210-20. PMID 10903846 DOI: 10.1006/Geno.2000.6216 |
0.572 |
|
| 2000 |
Ge K, Minhas F, Duhadaway J, Mao NC, Wilson D, Buccafusca R, Sakamuro D, Nelson P, Malkowicz SB, Tomaszewski J, Prendergast GC. Loss of heterozygosity and tumor suppressor activity of Bin1 in prostate carcinoma. International Journal of Cancer. 86: 155-61. PMID 10738240 DOI: 10.1002/(Sici)1097-0215(20000415)86:2<155::Aid-Ijc2>3.0.Co;2-M |
0.698 |
|
| 2000 |
Ge K, Duhadaway J, Sakamuro D, Wechsler-Reya R, Reynolds C, Prendergast GC. Losses of the tumor suppressor BIN1 in breast carcinoma are frequent and reflect deficits in programmed cell death capacity International Journal of Cancer. 85: 376-383. PMID 10652430 DOI: 10.1002/(Sici)1097-0215(20000201)85:3<376::Aid-Ijc14>3.0.Co;2-1 |
0.723 |
|
| 1999 |
Ge K, DuHadaway J, Du W, Herlyn M, Rodeck U, Prendergast GC. Mechanism for elimination of a tumor suppressor: aberrant splicing of a brain-specific exon causes loss of function of Bin1 in melanoma. Proceedings of the National Academy of Sciences of the United States of America. 96: 9689-94. PMID 10449755 DOI: 10.1073/Pnas.96.17.9689 |
0.594 |
|
| 1998 |
Xu L, Ge K, Zheng Z, Sun L, Liu X. Retroviral-Mediated Suicide Gene Therapy Of Experimental Glioma Chinese Journal of Cancer Research. 10: 157-161. DOI: 10.1007/Bf02948352 |
0.366 |
|
| 1997 |
Ge K, Xu L, Zheng Z, Xu D, Sun L, Liu X. Transduction of cytosine deaminase gene makes rat glioma cells highly sensitive to 5‐fluorocytosine International Journal of Cancer. 71: 675-679. PMID 9178825 DOI: 10.1002/(Sici)1097-0215(19970516)71:4<675::Aid-Ijc26>3.0.Co;2-9 |
0.319 |
|
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