Joel Linden - Publications

University of Virginia, Charlottesville, VA 
Animal Physiology Biology, Medical Biophysics

144 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2014 Cekic C, Day YJ, Sag D, Linden J. Myeloid expression of adenosine A2A receptor suppresses T and NK cell responses in the solid tumor microenvironment. Cancer Research. 74: 7250-9. PMID 25377469 DOI: 10.1158/0008-5472.Can-13-3583  0.32
2014 Field JJ, Nathan DG, Linden J. The role of adenosine signaling in sickle cell therapeutics. Hematology/Oncology Clinics of North America. 28: 287-99. PMID 24589267 DOI: 10.1016/J.Hoc.2013.11.003  0.44
2014 Kennedy DP, McRobb FM, Leonhardt SA, Purdy M, Figler H, Marshall MA, Chordia M, Figler R, Linden J, Abagyan R, Yeager M. The second extracellular loop of the adenosine A1 receptor mediates activity of allosteric enhancers. Molecular Pharmacology. 85: 301-9. PMID 24217444 DOI: 10.1124/Mol.113.088682  0.44
2013 Cekic C, Sag D, Day YJ, Linden J. Extracellular adenosine regulates naive T cell development and peripheral maintenance. The Journal of Experimental Medicine. 210: 2693-706. PMID 24145516 DOI: 10.1084/Jem.20130249  0.32
2013 Lin G, Field JJ, Yu JC, Ken R, Neuberg D, Nathan DG, Linden J. NF-κB is activated in CD4+ iNKT cells by sickle cell disease and mediates rapid induction of adenosine A2A receptors. Plos One. 8: e74664. PMID 24124453 DOI: 10.1371/Journal.Pone.0074664  0.44
2013 Field JJ, Lin G, Okam MM, Majerus E, Keefer J, Onyekwere O, Ross A, Campigotto F, Neuberg D, Linden J, Nathan DG. Sickle cell vaso-occlusion causes activation of iNKT cells that is decreased by the adenosine A2A receptor agonist regadenoson. Blood. 121: 3329-34. PMID 23377438 DOI: 10.1182/Blood-2012-11-465963  0.44
2013 Harris DA, Zhao Y, LaPar DJ, Emaminia A, Steidle JF, Stoler M, Linden J, Kron IL, Lau CL. Inhibiting CXCL12 blocks fibrocyte migration and differentiation and attenuates bronchiolitis obliterans in a murine heterotopic tracheal transplant model. The Journal of Thoracic and Cardiovascular Surgery. 145: 854-61. PMID 22626514 DOI: 10.1016/J.Jtcvs.2012.03.079  0.44
2012 Nathan DG, Field J, Lin G, Neuberg D, Majerus E, Onyekwere O, Keefer J, Okam M, Ross A, Linden J. Sickle cell disease (SCD), iNKT cells, and regadenoson infusion. Transactions of the American Clinical and Climatological Association. 123: 312-7; discussion 31. PMID 23303999  0.44
2012 Li Y, Figler RA, Kolling G, Bracken TC, Rieger J, Stevenson RW, Linden J, Guerrant RL, Warren CA. Adenosine A2A receptor activation reduces recurrence and mortality from Clostridium difficile infection in mice following vancomycin treatment. Bmc Infectious Diseases. 12: 342. PMID 23217055 DOI: 10.1186/1471-2334-12-342  0.44
2012 Li L, Huang L, Ye H, Song SP, Bajwa A, Lee SJ, Moser EK, Jaworska K, Kinsey GR, Day YJ, Linden J, Lobo PI, Rosin DL, Okusa MD. Dendritic cells tolerized with adenosine A₂AR agonist attenuate acute kidney injury. The Journal of Clinical Investigation. 122: 3931-42. PMID 23093781 DOI: 10.1172/Jci63170  0.32
2012 Warren CA, Li Y, Calabrese GM, Freire RS, Zaja-Milatovic S, van Opstal E, Figler RA, Linden J, Guerrant RL. Contribution of adenosine A(2B) receptors in Clostridium difficile intoxication and infection. Infection and Immunity. 80: 4463-73. PMID 23045479 DOI: 10.1128/Iai.00782-12  0.44
2012 Barletta KE, Cagnina RE, Burdick MD, Linden J, Mehrad B. Adenosine A(2B) receptor deficiency promotes host defenses against gram-negative bacterial pneumonia. American Journal of Respiratory and Critical Care Medicine. 186: 1044-50. PMID 22997203 DOI: 10.1164/Rccm.201204-0622Oc  0.64
2012 Field JJ, Burdick MD, DeBaun MR, Strieter BA, Liu L, Mehrad B, Rose CE, Linden J, Strieter RM. The role of fibrocytes in sickle cell lung disease. Plos One. 7: e33702. PMID 22442712 DOI: 10.1371/Journal.Pone.0033702  0.44
2012 Warren CA, Calabrese GM, Li Y, Pawlowski SW, Figler RA, Rieger J, Ernst PB, Linden J, Guerrant RL. Effects of adenosine Aâ‚‚A receptor activation and alanyl-glutamine in Clostridium difficile toxin-induced ileitis in rabbits and cecitis in mice. Bmc Infectious Diseases. 12: 13. PMID 22264229 DOI: 10.1186/1471-2334-12-13  0.44
2012 Barletta KE, Cagnina RE, Wallace KL, Ramos SI, Mehrad B, Linden J. Leukocyte compartments in the mouse lung: distinguishing between marginated, interstitial, and alveolar cells in response to injury. Journal of Immunological Methods. 375: 100-10. PMID 21996427 DOI: 10.1016/J.Jim.2011.09.013  0.96
2011 Emaminia A, Lapar DJ, Zhao Y, Steidle JF, Harris DA, Laubach VE, Linden J, Kron IL, Lau CL. Adenosine Aâ‚‚A agonist improves lung function during ex vivo lung perfusion. The Annals of Thoracic Surgery. 92: 1840-6. PMID 22051279 DOI: 10.1016/J.Athoracsur.2011.06.062  0.44
2011 Jacobson KA, Linden J. Pharmacology of purine and pyrimidine receptors. Preface. Advances in Pharmacology (San Diego, Calif.). 61: xv-xvi. PMID 21586353 DOI: 10.1016/B978-0-12-385526-8.00020-5  0.44
2011 Field JJ, Nathan DG, Linden J. Targeting iNKT cells for the treatment of sickle cell disease. Clinical Immunology (Orlando, Fla.). 140: 177-83. PMID 21429807 DOI: 10.1016/J.Clim.2011.03.002  0.44
2011 Fredholm BB, IJzerman AP, Jacobson KA, Linden J, Müller CE. International Union of Basic and Clinical Pharmacology. LXXXI. Nomenclature and classification of adenosine receptors--an update. Pharmacological Reviews. 63: 1-34. PMID 21303899 DOI: 10.1124/Pr.110.003285  0.44
2011 Figler RA, Wang G, Srinivasan S, Jung DY, Zhang Z, Pankow JS, Ravid K, Fredholm B, Hedrick CC, Rich SS, Kim JK, LaNoue KF, Linden J. Links between Insulin resistance, adenosine A2B receptors, and inflammatory markers in mice and humans Diabetes. 60: 669-679. PMID 21270276 DOI: 10.2337/Db10-1070  0.44
2010 Polanowska-Grabowska R, Wallace K, Field JJ, Chen L, Marshall MA, Figler R, Gear AR, Linden J. P-selectin-mediated platelet-neutrophil aggregate formation activates neutrophils in mouse and human sickle cell disease. Arteriosclerosis, Thrombosis, and Vascular Biology. 30: 2392-9. PMID 21071696 DOI: 10.1161/Atvbaha.110.211615  0.44
2010 Yang M, Chordia MD, Li F, Huang T, Linden J, MacDonald TL. Neutrophil- and myeloperoxidase-mediated metabolism of reduced nimesulide: Evidence for bioactivation Chemical Research in Toxicology. 23: 1691-1700. PMID 20939553 DOI: 10.1021/Tx1001496  0.44
2010 Wallace KL, Linden J. Adenosine A2A receptors induced on iNKT and NK cells reduce pulmonary inflammation and injury in mice with sickle cell disease. Blood. 116: 5010-20. PMID 20798237 DOI: 10.1182/Blood-2010-06-290643  0.96
2010 Gazoni LM, Walters DM, Unger EB, Linden J, Kron IL, Laubach VE. Activation of A1, A2A, or A3 adenosine receptors attenuates lung ischemia-reperfusion injury. The Journal of Thoracic and Cardiovascular Surgery. 140: 440-6. PMID 20398911 DOI: 10.1016/J.Jtcvs.2010.03.002  0.44
2010 Chhabra P, Wang K, Zeng Q, Jecmenica M, Langman L, Linden J, Ketchum RJ, Brayman KL. Adenosine A(2A) agonist administration improves islet transplant outcome: Evidence for the role of innate immunity in islet graft rejection. Cell Transplantation. 19: 597-612. PMID 20350347 DOI: 10.3727/096368910X491806  0.44
2010 Sun WC, Berghaus LJ, Moore JN, Hurley DJ, Vandenplas ML, Thompson R, Linden J. Lipopolysaccharide and TNF-alpha modify adenosine A(2A) receptor expression and function in equine monocytes. Veterinary Immunology and Immunopathology. 135: 289-95. PMID 20056284 DOI: 10.1016/J.Vetimm.2009.12.001  0.44
2010 Sharma AK, Laubach VE, Ramos SI, Zhao Y, Stukenborg G, Linden J, Kron IL, Yang Z. Adenosine A2A receptor activation on CD4+ T lymphocytes and neutrophils attenuates lung ischemia-reperfusion injury. The Journal of Thoracic and Cardiovascular Surgery. 139: 474-82. PMID 19909990 DOI: 10.1016/J.Jtcvs.2009.08.033  0.64
2010 Lappas CM, Liu PC, Linden J, Kang EM, Malech HL. Adenosine A2A receptor activation limits graft-versus-host disease after allogenic hematopoietic stem cell transplantation. Journal of Leukocyte Biology. 87: 345-54. PMID 19889728 DOI: 10.1189/Jlb.0609388  0.48
2010 Sun WC, Moore JN, Hurley DJ, Vandenplas ML, Fortes B, Thompson R, Linden J. Differential modulation of lipopolysaccharide-induced expression of inflammatory genes in equine monocytes through activation of adenosine A2A receptors. Veterinary Immunology and Immunopathology. 134: 169-77. PMID 19766323 DOI: 10.1016/J.Vetimm.2009.08.018  0.44
2009 Cagnina RE, Ramos SI, Marshall MA, Wang G, Frazier CR, Linden J. Adenosine A2B receptors are highly expressed on murine type II alveolar epithelial cells. American Journal of Physiology. Lung Cellular and Molecular Physiology. 297: L467-74. PMID 19574419 DOI: 10.1152/Ajplung.90553.2008  0.44
2009 Wallace KL, Marshall MA, Ramos SI, Lannigan JA, Field JJ, Strieter RM, Linden J. NKT cells mediate pulmonary inflammation and dysfunction in murine sickle cell disease through production of IFN-gamma and CXCR3 chemokines. Blood. 114: 667-76. PMID 19433855 DOI: 10.1182/Blood-2009-02-205492  0.44
2009 Lau CL, Zhao Y, Kim J, Kron IL, Sharma A, Yang Z, Laubach VE, Linden J, Ailawadi G, Pinsky DJ. Enhanced fibrinolysis protects against lung ischemia-reperfusion injury. The Journal of Thoracic and Cardiovascular Surgery. 137: 1241-8. PMID 19379998 DOI: 10.1016/J.Jtcvs.2008.12.029  0.44
2009 Locke LW, Chordia MD, Zhang Y, Kundu B, Kennedy D, Landseadel J, Xiao L, Fairchild KD, Berr SS, Linden J, Pan D. A novel neutrophil-specific PET imaging agent: cFLFLFK-PEG-64Cu. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 50: 790-7. PMID 19372473 DOI: 10.2967/Jnumed.108.056127  0.44
2009 Wilson JM, Ross WG, Agbai ON, Frazier R, Figler RA, Rieger J, Linden J, Ernst PB. The A2B adenosine receptor impairs the maturation and immunogenicity of dendritic cells. Journal of Immunology (Baltimore, Md. : 1950). 182: 4616-23. PMID 19342636 DOI: 10.4049/Jimmunol.0801279  0.44
2009 Koizumi S, Odashima M, Otaka M, Jin M, Linden J, Watanabe S, Ohnishi H. Attenuation of gastric mucosal inflammation induced by indomethacin through activation of the A2A adenosine receptor in rats. Journal of Gastroenterology. 44: 419-25. PMID 19333545 DOI: 10.1007/S00535-009-0028-8  0.44
2009 Alam MS, Kurtz CC, Rowlett RM, Reuter BK, Wiznerowicz E, Das S, Linden J, Crowe SE, Ernst PB. CD73 is expressed by human regulatory T helper cells and suppresses proinflammatory cytokine production and Helicobacter felis-induced gastritis in mice. The Journal of Infectious Diseases. 199: 494-504. PMID 19281303 DOI: 10.1086/596205  0.44
2009 Alam MS, Kurtz CC, Wilson JM, Burnette BR, Wiznerowicz EB, Ross WG, Rieger JM, Figler RA, Linden J, Crowe SE, Ernst PB. A2A adenosine receptor (AR) activation inhibits pro-inflammatory cytokine production by human CD4+ helper T cells and regulates Helicobacter-induced gastritis and bacterial persistence. Mucosal Immunology. 2: 232-42. PMID 19262506 DOI: 10.1038/Mi.2009.4  0.44
2009 Awad AS, Rouse M, Huang L, Vergis AL, Reutershan J, Cathro HP, Linden J, Okusa MD. Compartmentalization of neutrophils in the kidney and lung following acute ischemic kidney injury. Kidney International. 75: 689-98. PMID 19129795 DOI: 10.1038/Ki.2008.648  0.44
2009 Sullivan GW, Linden J. Role of neutrophil purinergic receptors in organ dysfunction Journal of Organ Dysfunction. 5: 147-160. DOI: 10.1080/17471060701682310  0.48
2008 Yang Z, Linden J, Berr SS, Kron IL, Beller GA, French BA. Timing of adenosine 2A receptor stimulation relative to reperfusion has differential effects on infarct size and cardiac function as assessed in mice by MRI. American Journal of Physiology. Heart and Circulatory Physiology. 295: H2328-35. PMID 18849340 DOI: 10.1152/Ajpheart.00091.2008  0.44
2008 Rork TH, Wallace KL, Kennedy DP, Marshall MA, Lankford AR, Linden J. Adenosine A2A receptor activation reduces infarct size in the isolated, perfused mouse heart by inhibiting resident cardiac mast cell degranulation. American Journal of Physiology. Heart and Circulatory Physiology. 295: H1825-33. PMID 18757481 DOI: 10.1152/Ajpheart.495.2008  0.44
2008 Kolachala VL, Vijay-Kumar M, Dalmasso G, Yang D, Linden J, Wang L, Gewirtz A, Ravid K, Merlin D, Sitaraman SV. A2B adenosine receptor gene deletion attenuates murine colitis. Gastroenterology. 135: 861-70. PMID 18601927 DOI: 10.1053/J.Gastro.2008.05.049  0.44
2008 Kolachala VL, Ruble BK, Vijay-Kumar M, Wang L, Mwangi S, Figler HE, Figler RA, Srinivasan S, Gewirtz AT, Linden J, Merlin D, Sitaraman SV. Blockade of adenosine A 2B receptors ameliorates murine colitis British Journal of Pharmacology. 155: 127-137. PMID 18536750 DOI: 10.1038/Bjp.2008.227  0.44
2008 Shen HY, Coelho JE, Ohtsuka N, Canas PM, Day YJ, Huang QY, Rebola N, Yu L, Boison D, Cunha RA, Linden J, Tsien JZ, Chen JF. A critical role of the adenosine A2A receptor in extrastriatal neurons in modulating psychomotor activity as revealed by opposite phenotypes of striatum and forebrain A2A receptor knock-outs. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 2970-5. PMID 18354001 DOI: 10.1523/Jneurosci.5255-07.2008  0.44
2008 Reece TB, Tribble CG, Okonkwo DO, Davis JD, Maxey TS, Gazoni LM, Linden J, Kron IL, Kern JA. Early adenosine receptor activation ameliorates spinal cord reperfusion injury. Journal of Cardiovascular Medicine (Hagerstown, Md.). 9: 363-7. PMID 18334890 DOI: 10.2459/Jcm.0B013E3282Eee836  0.44
2008 Yu L, Shen HY, Coelho JE, Araújo IM, Huang QY, Day YJ, Rebola N, Canas PM, Rapp EK, Ferrara J, Taylor D, Müller CE, Linden J, Cunha RA, Chen JF. Adenosine A2A receptor antagonists exert motor and neuroprotective effects by distinct cellular mechanisms. Annals of Neurology. 63: 338-46. PMID 18300283 DOI: 10.1002/Ana.21313  0.44
2008 Gazoni LM, Laubach VE, Mulloy DP, Bellizzi A, Unger EB, Linden J, Ellman PI, Lisle TC, Kron IL. Additive protection against lung ischemia-reperfusion injury by adenosine A2A receptor activation before procurement and during reperfusion. The Journal of Thoracic and Cardiovascular Surgery. 135: 156-65. PMID 18179933 DOI: 10.1016/J.Jtcvs.2007.08.041  0.44
2008 Awad AS, Rouse M, Liu L, Vergis AL, Rosin DL, Linden J, Sedor JR, Okusa MD. Activation of adenosine 2A receptors preserves structure and function of podocytes. Journal of the American Society of Nephrology : Jasn. 19: 59-68. PMID 18045850 DOI: 10.1681/Asn.2007030276  0.44
2008 Sun WC, Moore JN, Hurley DJ, Vandenplas ML, Linden J, Cao Z, Murray TF. Adenosine A2A receptor agonists inhibit lipopolysaccharide-induced production of tumor necrosis factor-alpha by equine monocytes. Veterinary Immunology and Immunopathology. 121: 91-100. PMID 17913243 DOI: 10.1016/J.Vetimm.2007.08.011  0.44
2008 Zarek PE, Huang CT, Lutz ER, Kowalski J, Horton MR, Linden J, Drake CG, Powell JD. A2A receptor signaling promotes peripheral tolerance by inducing T-cell anergy and the generation of adaptive regulatory T cells. Blood. 111: 251-9. PMID 17909080 DOI: 10.1182/Blood-2007-03-081646  0.44
2008 Rork TH, Wallace KL, Kennedy DP, Marshall MA, Lankford AR, Linden J. Resident cardiac mast cells contribute to ischemia-reperfusion injury in the isolated, perfused mouse heart The Faseb Journal. 22: 47-47. DOI: 10.1096/Fasebj.22.2_Supplement.47  0.96
2007 Zhang Y, Kundu B, Fairchild KD, Locke L, Berr SS, Linden J, Pan D. Synthesis of novel neutrophil-specific imaging agents for Positron Emission Tomography (PET) imaging. Bioorganic & Medicinal Chemistry Letters. 17: 6876-8. PMID 17959381 DOI: 10.1016/J.Bmcl.2007.10.013  0.44
2007 Clark AN, Youkey R, Liu X, Jia L, Blatt R, Day YJ, Sullivan GW, Linden J, Tucker AL. A1 adenosine receptor activation promotes angiogenesis and release of VEGF from monocytes. Circulation Research. 101: 1130-8. PMID 17901362 DOI: 10.1161/Circresaha.107.150110  0.44
2007 Sun WC, Moore JN, Hurley DJ, Vandenplas ML, Linden JM, Murray TF. Pharmacologic characterization of novel adenosine A2A receptor agonists in equine neutrophils. American Journal of Veterinary Research. 68: 981-7. PMID 17764413 DOI: 10.2460/ajvr.68.9.981  0.44
2007 Reutershan J, Cagnina RE, Chang D, Linden J, Ley K. Therapeutic anti-inflammatory effects of myeloid cell adenosine receptor A2a stimulation in lipopolysaccharide-induced lung injury. Journal of Immunology (Baltimore, Md. : 1950). 179: 1254-63. PMID 17617618 DOI: 10.4049/Jimmunol.179.2.1254  0.64
2007 Deaglio S, Dwyer KM, Gao W, Friedman D, Usheva A, Erat A, Chen JF, Enjyoji K, Linden J, Oukka M, Kuchroo VK, Strom TB, Robson SC. Adenosine generation catalyzed by CD39 and CD73 expressed on regulatory T cells mediates immune suppression. The Journal of Experimental Medicine. 204: 1257-65. PMID 17502665 DOI: 10.1084/Jem.20062512  0.44
2007 Sevigny CP, Li L, Awad AS, Huang L, McDuffie M, Linden J, Lobo PI, Okusa MD. Activation of adenosine 2A receptors attenuates allograft rejection and alloantigen recognition. Journal of Immunology (Baltimore, Md. : 1950). 178: 4240-9. PMID 17371980 DOI: 10.4049/Jimmunol.178.7.4240  0.44
2007 Glover DK, Ruiz M, Takehana K, Petruzella FD, Rieger JM, Macdonald TL, Watson DD, Linden J, Beller GA. Cardioprotection by adenosine A2A agonists in a canine model of myocardial stunning produced by multiple episodes of transient ischemia. American Journal of Physiology. Heart and Circulatory Physiology. 292: H3164-71. PMID 17308004 DOI: 10.1152/Ajpheart.00743.2005  0.44
2006 Kiesman WF, Zhao J, Conlon PR, Dowling JE, Petter RC, Lutterodt F, Jin X, Smits G, Fure M, Jayaraj A, Kim J, Sullivan G, Linden J. Potent and orally bioavailable 8-bicyclo[2.2.2]octylxanthines as adenosine A1 receptor antagonists. Journal of Medicinal Chemistry. 49: 7119-31. PMID 17125264 DOI: 10.1021/Jm0605381  0.44
2006 Lappas CM, Day YJ, Marshall MA, Engelhard VH, Linden J. Adenosine A2A receptor activation reduces hepatic ischemia reperfusion injury by inhibiting CD1d-dependent NKT cell activation. The Journal of Experimental Medicine. 203: 2639-48. PMID 17088433 DOI: 10.1084/Jem.20061097  0.44
2006 Yang Z, Day YJ, Toufektsian MC, Xu Y, Ramos SI, Marshall MA, French BA, Linden J. Myocardial infarct-sparing effect of adenosine A2A receptor activation is due to its action on CD4+ T lymphocytes. Circulation. 114: 2056-64. PMID 17060376 DOI: 10.1161/Circulationaha.106.649244  0.44
2006 McIntire WE, MacCleery G, Murphree LJ, Kerchner KR, Linden J, Garrison JC. Influence of differential stability of G protein βγ dimers containing the γ11 subunit on functional activity at the M1 muscarinic receptor, A1 adenosine receptor, and phospholipase C-β. Biochemistry. 45: 11616-31. PMID 16981721 DOI: 10.1021/Bi0604882  0.44
2006 Pickel VM, Chan J, Linden J, Rosin DL. Subcellular distributions of adenosine A1 and A2A receptors in the rat dorsomedial nucleus of the solitary tract at the level of the area postrema. Synapse (New York, N.Y.). 60: 496-509. PMID 16952160 DOI: 10.1002/Syn.20326  0.44
2006 Naganuma M, Wiznerowicz EB, Lappas CM, Linden J, Worthington MT, Ernst PB. Cutting edge: Critical role for A2A adenosine receptors in the T cell-mediated regulation of colitis. Journal of Immunology (Baltimore, Md. : 1950). 177: 2765-9. PMID 16920910 DOI: 10.4049/Jimmunol.177.5.2765  0.44
2006 Reece TB, Kron IL, Okonkwo DO, Laurent JJ, Tache-Leon C, Maxey TS, Ellman PI, Linden J, Tribble CG, Kern JA. Functional and cytoarchitectural spinal cord protection by ATL-146e after ischemia/reperfusion is mediated by adenosine receptor agonism. Journal of Vascular Surgery. 44: 392-7. PMID 16890874 DOI: 10.1016/J.Jvs.2006.04.032  0.44
2006 Odashima M, Otaka M, Jin M, Horikawa Y, Matsuhashi T, Ohba R, Linden J, Watanabe S. A selective adenosine A2A receptor agonist, ATL-146e, prevents concanavalin A-induced acute liver injury in mice. Biochemical and Biophysical Research Communications. 347: 949-54. PMID 16859640 DOI: 10.1016/J.Bbrc.2006.06.185  0.44
2006 Li Y, Oskouian RJ, Day YJ, Rieger JM, Liu L, Kern JA, Linden J. Mouse spinal cord compression injury is reduced by either activation of the adenosine A2A receptor on bone marrow-derived cells or deletion of the A2A receptor on non-bone marrow-derived cells. Neuroscience. 141: 2029-39. PMID 16777350 DOI: 10.1016/J.Neuroscience.2006.05.014  0.44
2006 Cavalcante IC, Castro MV, Barreto AR, Sullivan GW, Vale M, Almeida PR, Linden J, Rieger JM, Cunha FQ, Guerrant RL, Ribeiro RA, Brito GA. Effect of novel A2A adenosine receptor agonist ATL 313 on Clostridium difficile toxin A-induced murine ileal enteritis. Infection and Immunity. 74: 2606-12. PMID 16622196 DOI: 10.1128/Iai.74.5.2606-2612.2006  0.48
2006 Li Y, Oskouian RJ, Day YJ, Kern JA, Linden J. Optimization of a mouse locomotor rating system to evaluate compression-induced spinal cord injury: correlation of locomotor and morphological injury indices. Journal of Neurosurgery. Spine. 4: 165-73. PMID 16506485 DOI: 10.3171/Spi.2006.4.2.165  0.32
2006 Okonkwo DO, Reece TB, Laurent JJ, Hawkins AS, Ellman PI, Linden J, Kron IL, Tribble CG, Stone JR, Kern JA. A comparison of adenosine A2A agonism and methylprednisolone in attenuating neuronal damage and improving functional outcome after experimental traumatic spinal cord injury in rabbits. Journal of Neurosurgery. Spine. 4: 64-70. PMID 16506468 DOI: 10.3171/Spi.2006.4.1.64  0.44
2006 Day YJ, Huang L, Ye H, Li L, Linden J, Okusa MD. Renal ischemia-reperfusion injury and adenosine 2A receptor-mediated tissue protection: the role of CD4+ T cells and IFN-gamma. Journal of Immunology (Baltimore, Md. : 1950). 176: 3108-14. PMID 16493070 DOI: 10.4049/Jimmunol.176.5.3108  0.32
2006 Odashima M, Otaka M, Jin M, Komatsu K, Wada I, Horikawa Y, Matsuhashi T, Hatakeyama N, Oyake J, Ohba R, Watanabe S, Linden J. Attenuation of gastric mucosal inflammation induced by aspirin through activation of A2A adenosine receptor in rats. World Journal of Gastroenterology. 12: 568-73. PMID 16489670 DOI: 10.3748/Wjg.V12.I4.568  0.44
2006 Reece TB, Okonkwo DO, Ellman PI, Maxey TS, Tache-Leon C, Warren PS, Laurent JJ, Linden J, Kron IL, Tribble CG, Kern JA. Comparison of systemic and retrograde delivery of adenosine A2A agonist for attenuation of spinal cord injury after thoracic aortic cross-clamping. The Annals of Thoracic Surgery. 81: 902-9. PMID 16488692 DOI: 10.1016/J.Athoracsur.2005.09.023  0.44
2006 Zhu R, Frazier CR, Linden J, Macdonald TL. N6-ethyl-2-alkynyl NECAs, selective human A3 adenosine receptor agonists. Bioorganic & Medicinal Chemistry Letters. 16: 2416-8. PMID 16487705 DOI: 10.1016/J.Bmcl.2006.01.110  0.44
2006 Kiesman WF, Zhao J, Conlon PR, Petter RC, Jin X, Smits G, Lutterodt F, Sullivan GW, Linden J. Norbornyllactone-substituted xanthines as adenosine A(1) receptor antagonists. Bioorganic & Medicinal Chemistry. 14: 3654-61. PMID 16458010 DOI: 10.1016/J.Bmc.2006.01.021  0.48
2006 Awad AS, Huang L, Ye H, Duong ET, Bolton WK, Linden J, Okusa MD. Adenosine A2A receptor activation attenuates inflammation and injury in diabetic nephropathy. American Journal of Physiology. Renal Physiology. 290: F828-37. PMID 16332931 DOI: 10.1152/Ajprenal.00310.2005  0.44
2006 Li Y, Oskouian RJ, Shaffrey CI, Day YJ, Bumpass DB, Roy RJ, Berr SS, Kern JA, Linden J. A novel and reproducible mouse model of spinal cord ischemia/reperfusion injury Topics in Spinal Cord Injury Rehabilitation. 12: 1-10. DOI: 10.1310/78Ay-G6Qd-2Lhx-Yb8Q  0.44
2005 Chordia MD, Zigler M, Murphree LJ, Figler H, Macdonald TL, Olsson RA, Linden J. 6-Aryl-8H-indeno[1,2-d]thiazol-2-ylamines: A1 adenosine receptor agonist allosteric enhancers having improved potency Journal of Medicinal Chemistry. 48: 5131-5139. PMID 16078833 DOI: 10.1021/Jm049132J  0.44
2005 Murphree LJ, Sullivan GW, Marshall MA, Linden J. Lipopolysaccharide rapidly modifies adenosine receptor transcripts in murine and human macrophages: role of NF-kappaB in A(2A) adenosine receptor induction. The Biochemical Journal. 391: 575-80. PMID 16022683 DOI: 10.1042/Bj20050888  0.44
2005 Lappas CM, Sullivan GW, Linden J. Adenosine A2A agonists in development for the treatment of inflammation. Expert Opinion On Investigational Drugs. 14: 797-806. PMID 16022569 DOI: 10.1517/13543784.14.7.797  0.48
2005 Odashima M, Bamias G, Rivera-Nieves J, Linden J, Nast CC, Moskaluk CA, Marini M, Sugawara K, Kozaiwa K, Otaka M, Watanabe S, Cominelli F. Activation of A2A adenosine receptor attenuates intestinal inflammation in animal models of inflammatory bowel disease. Gastroenterology. 129: 26-33. PMID 16012931 DOI: 10.1053/J.Gastro.2005.05.032  0.44
2005 Odashima M, Otaka M, Jin M, Komatsu K, Wada I, Matsuhashi T, Horikawa Y, Hatakeyama N, Oyake J, Ohba R, Linden J, Watanabe S. Selective A2A adenosine agonist ATL-146e attenuates acute lethal liver injury in mice. Journal of Gastroenterology. 40: 526-9. PMID 15942719 DOI: 10.1007/S00535-005-1609-9  0.44
2005 Day YJ, Li Y, Rieger JM, Ramos SI, Okusa MD, Linden J. A2A adenosine receptors on bone marrow-derived cells protect liver from ischemia-reperfusion injury. Journal of Immunology (Baltimore, Md. : 1950). 174: 5040-6. PMID 15814735 DOI: 10.4049/Jimmunol.174.8.5040  0.44
2005 Odashima M, Otaka M, Jin M, Komatsu K, Wada I, Matsuhashi T, Horikawa Y, Hatakeyama N, Oyake J, Ohba R, Linden J, Watanabe S. Selective adenosine A receptor agonist, ATL-146e, attenuates stress-induced gastric lesions in rats. Journal of Gastroenterology and Hepatology. 20: 275-80. PMID 15683432 DOI: 10.1111/J.1440-1746.2004.03555.X  0.44
2005 Lappas CM, Rieger JM, Linden J. A2A adenosine receptor induction inhibits IFN-gamma production in murine CD4+ T cells. Journal of Immunology (Baltimore, Md. : 1950). 174: 1073-80. PMID 15634932 DOI: 10.4049/Jimmunol.174.2.1073  0.44
2005 Bastia E, Xu YH, Scibelli AC, Day YJ, Linden J, Chen JF, Schwarzschild MA. A crucial role for forebrain adenosine A(2A) receptors in amphetamine sensitization. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 30: 891-900. PMID 15602504 DOI: 10.1038/Sj.Npp.1300630  0.44
2005 Glover DK, Riou LM, Ruiz M, Sullivan GW, Linden J, Rieger JM, Macdonald TL, Watson DD, Beller GA. Reduction of infarct size and postischemic inflammation from ATL-146e, a highly selective adenosine A2A receptor agonist, in reperfused canine myocardium. American Journal of Physiology. Heart and Circulatory Physiology. 288: H1851-8. PMID 15591104 DOI: 10.1152/Ajpheart.00362.2004  0.44
2004 Reece TB, Okonkwo DO, Ellman PI, Warren PS, Smith RL, Hawkins AS, Linden J, Kron IL, Tribble CG, Kern JA. The evolution of ischemic spinal cord injury in function, cytoarchitecture, and inflammation and the effects of adenosine A2A receptor activation. The Journal of Thoracic and Cardiovascular Surgery. 128: 925-32. PMID 15573078 DOI: 10.1016/J.Jtcvs.2004.08.019  0.44
2004 Reece TB, Davis JD, Okonkwo DO, Maxey TS, Ellman PI, Li X, Linden J, Tribble CG, Kron IL, Kern JA. Adenosine A2A analogue reduces long-term neurologic injury after blunt spinal trauma. The Journal of Surgical Research. 121: 130-4. PMID 15313386 DOI: 10.1016/J.Jss.2004.04.006  0.44
2004 Sullivan GW, Fang G, Linden J, Scheld WM. A2A adenosine receptor activation improves survival in mouse models of endotoxemia and sepsis. The Journal of Infectious Diseases. 189: 1897-904. PMID 15122527 DOI: 10.1086/386311  0.44
2004 Joshi E, Chordia MD, Macdonald TL, Linden J, Olsson R. Regioselective oxidation of 2-amino-3-aroyl-4,5-dialkylthiophenes by DMSO Bioorganic and Medicinal Chemistry Letters. 14: 929-933. PMID 15012996 DOI: 10.1016/J.Bmcl.2003.12.010  0.44
2004 Day YJ, Marshall MA, Huang L, McDuffie MJ, Okusa MD, Linden J. Protection from ischemic liver injury by activation of A2A adenosine receptors during reperfusion: Inhibition of chemokine induction American Journal of Physiology - Gastrointestinal and Liver Physiology. 286: G285-G293. PMID 14715520 DOI: 10.1152/Ajpgi.00348.2003  0.44
2004 Sullivan GW, Lee DD, Ross WG, DiVietro JA, Lappas CM, Lawrence MB, Linden J. Activation of A2A adenosine receptors inhibits expression of alpha 4/beta 1 integrin (very late antigen-4) on stimulated human neutrophils. Journal of Leukocyte Biology. 75: 127-34. PMID 14525968 DOI: 10.1189/Jlb.0603300  0.48
2003 Rosin DL, Hettinger BD, Lee A, Linden J. Anatomy of adenosine A2A receptors in brain: Morphological substrates for integration of striatal function Neurology. 61: S12-S18. PMID 14663003 DOI: 10.1212/01.Wnl.0000095205.33940.99  0.44
2003 Figler H, Olsson RA, Linden J. Allosteric enhancers of A1 adenosine receptors increase receptor-G protein coupling and counteract Guanine nucleotide effects on agonist binding. Molecular Pharmacology. 64: 1557-64. PMID 14645687 DOI: 10.1124/Mol.64.6.1557  0.44
2003 Day YJ, Huang L, McDuffie MJ, Rosin DL, Ye H, Chen JF, Schwarzschild MA, Fink JS, Linden J, Okusa MD. Renal protection from ischemia mediated by A2A adenosine receptors on bone marrow-derived cells. The Journal of Clinical Investigation. 112: 883-91. PMID 12975473 DOI: 10.1172/Jci15483  0.44
2003 Lütjens H, Zickgraf A, Figler H, Linden J, Olsson RA, Scammells PJ. 2-Amino-3-benzoylthiophene allosteric enhancers of A1 adenosine agonist binding: new 3, 4-, and 5-modifications. Journal of Medicinal Chemistry. 46: 1870-7. PMID 12723950 DOI: 10.1021/Jm020295M  0.44
2002 Riou LM, Ruiz M, Rieger JM, Macdonald TL, Watson DD, Linden J, Beller GA, Glover DK. Influence of propranolol, enalaprilat, verapamil, and caffeine on adenosine A2A-receptor-mediated coronary vasodilation Journal of the American College of Cardiology. 40: 1687-1694. PMID 12427424 DOI: 10.1016/S0735-1097(02)02372-0  0.44
2002 Fiser SM, Tribble CG, Kaza AK, Long SM, Kern JA, Cassada DC, Linden J, Rieger J, Laubach VE, Matisoff A, Kron IL. Adenosine A2A receptor activation decreases reperfusion injury associated with high-flow reperfusion. The Journal of Thoracic and Cardiovascular Surgery. 124: 973-8. PMID 12407381 DOI: 10.1067/Mtc.2002.124886  0.44
2002 Cassada DC, Tribble CG, Long SM, Kaza AK, Linden J, Rieger JM, Rosin D, Kron IL, Kern JA. Adenosine A2A agonist reduces paralysis after spinal cord ischemia: correlation with A2A receptor expression on motor neurons. The Annals of Thoracic Surgery. 74: 846-9; discussion 84. PMID 12238849 DOI: 10.1016/S0003-4975(02)03793-1  0.44
2002 Cassada DC, Tribble CG, Young JS, Gangemi JJ, Gohari AR, Butler PD, Rieger JM, Kron IL, Linden J, Kern JA. Adenosine A2A analogue improves neurologic outcome after spinal cord trauma in the rabbit. The Journal of Trauma. 53: 225-9; discussion 22. PMID 12169926 DOI: 10.1097/00005373-200208000-00005  0.44
2002 Riou LM, Ruiz M, Sullivan GW, Linden J, Leong-Poi H, Lindner JR, Harris TD, Beller GA, Glover DK. Assessment of myocardial inflammation produced by experimental coronary occlusion and reperfusion with 99mTc-RP517, a new leukotriene B4 receptor antagonist that preferentially labels neutrophils in vivo. Circulation. 106: 592-8. PMID 12147542 DOI: 10.1161/01.Cir.0000023878.04716.6D  0.44
2002 Chordia MD, Murphree LJ, Macdonald TL, Linden J, Olsson RA. 2-Aminothiazoles: A new class of agonist allosteric enhancers of A1 adenosine receptors Bioorganic and Medicinal Chemistry Letters. 12: 1563-1566. PMID 12039562 DOI: 10.1016/S0960-894X(02)00236-6  0.44
2002 Cassada DC, Tribble CG, Long SM, Laubach VE, Kaza AK, Linden J, Nguyen BN, Rieger JM, Fiser SM, Kron IL, Kern JA. Adenosine A2A analogue ATL-146e reduces systemic tumor necrosing factor-alpha and spinal cord capillary platelet-endothelial cell adhesion molecule-1 expression after spinal cord ischemia. Journal of Vascular Surgery. 35: 994-8. PMID 12021717 DOI: 10.1067/Mva.2002.123091  0.44
2002 Kim SA, Marshall MA, Melman N, Kim HS, Müller CE, Linden J, Jacobson KA. Structure-activity relationships at human and rat A2B adenosine receptors of xanthine derivatives substituted at the 1-, 3-, 7-, and 8-positions. Journal of Medicinal Chemistry. 45: 2131-8. PMID 12014951 DOI: 10.1021/Jm0104318  0.44
2002 Murphree LJ, Marshall MA, Rieger JM, MacDonald TL, Linden J. Human A2A adenosine receptors: High-affinity agonist binding to receptor-g protein complexes containing Gβ4 Molecular Pharmacology. 61: 455-462. PMID 11809871 DOI: 10.1124/Mol.61.2.455  0.44
2002 Tranberg CE, Zickgraf A, Giunta BN, Luetjens H, Figler H, Murphree LJ, Falke R, Fleischer H, Linden J, Scammells PJ, Olsson RA. 2-Amino-3-aroyl-4,5-alkylthiophenes: agonist allosteric enhancers at human A(1) adenosine receptors. Journal of Medicinal Chemistry. 45: 382-9. PMID 11784142 DOI: 10.1021/jm010081p  0.44
2001 Cassada DC, Gangemi JJ, Rieger JM, Linden J, Kaza AK, Long SM, Kron IL, Tribble CG, Kern JA. Systemic adenosine A2A agonist ameliorates ischemic reperfusion injury in the rabbit spinal cord. The Annals of Thoracic Surgery. 72: 1245-50. PMID 11603444 DOI: 10.1016/S0003-4975(01)03057-0  0.44
2001 Glover DK, Ruiz M, Takehana K, Petruzella FD, Riou LM, Rieger JM, Macdonald TL, Watson DD, Linden J, Beller GA. Pharmacological stress myocardial perfusion imaging with the potent and selective A2A adenosine receptor agonists ATL193 and ATL146e administered by either intravenous infusion or bolus injection Circulation. 104: 1181-1187. PMID 11535577 DOI: 10.1161/Hc3601.093983  0.44
2001 Cassada DC, Tribble CG, Laubach VE, Nguyen BN, Rieger JM, Linden J, Kaza AK, Long SM, Kron IL, Kern JA. An adenosine A2A agonist, ATL-146e, reduces paralysis and apoptosis during rabbit spinal cord reperfusion. Journal of Vascular Surgery. 34: 482-8. PMID 11533601 DOI: 10.1067/Mva.2001.117996  0.44
2001 Cassada DC, Tribble CG, Kaza AK, Fiser SM, Long SM, Linden J, Rieger JM, Kron IL, Kern JA. Adenosine analogue reduces spinal cord reperfusion injury in a time-dependent fashion. Surgery. 130: 230-5. PMID 11490354 DOI: 10.1067/Msy.2001.115838  0.44
2001 Peirce SM, Skalak TC, Rieger JM, Macdonald TL, Linden J. Selective A2A adenosine receptor activation reduces skin pressure ulcer formation and inflammation American Journal of Physiology - Heart and Circulatory Physiology. 281: H67-H74. PMID 11406470 DOI: 10.1152/Ajpheart.2001.281.1.H67  0.44
2001 McPherson JA, Barringhaus KG, Bishop GG, Sanders JM, Rieger JM, Hesselbacher SE, Gimple LW, Powers ER, Macdonald T, Sullivan G, Linden J, Sarembock IJ. Adenosine A(2A) receptor stimulation reduces inflammation and neointimal growth in a murine carotid ligation model. Arteriosclerosis, Thrombosis, and Vascular Biology. 21: 791-6. PMID 11348876 DOI: 10.1161/01.Atv.21.5.791  0.44
2001 Hogan CJ, Fang GD, Scheld WM, Linden J, Diduch DR. Inhibiting the inflammatory response in joint sepsis. Arthroscopy : the Journal of Arthroscopic & Related Surgery : Official Publication of the Arthroscopy Association of North America and the International Arthroscopy Association. 17: 311-315. PMID 11239354 DOI: 10.1053/Jars.2001.21492  0.44
2001 Sullivan GW, Rieger JM, Scheld WM, Macdonald TL, Linden J. Cyclic AMP-dependent inhibition of human neutrophil oxidative activity by substituted 2-propynylcyclohexyl adenosine A(2A) receptor agonists. British Journal of Pharmacology. 132: 1017-26. PMID 11226132 DOI: 10.1038/Sj.Bjp.0703893  0.44
2001 Rieger JM, Brown ML, Sullivan GW, Linden J, Macdonald TL. Design, synthesis, and evaluation of novel A2A adenosine receptor agonists Journal of Medicinal Chemistry. 44: 531-539. PMID 11170643 DOI: 10.1021/Jm0003642  0.44
2001 Hettinger BD, Lee A, Linden J, Rosin DL. Ultrastructural localization of adenosine A2A receptors suggests multiple cellular sites for modulation of GABAergic neurons in rat striatum Journal of Comparative Neurology. 431: 331-346. PMID 11170009 DOI: 10.1002/1096-9861(20010312)431:3<331::Aid-Cne1074>3.0.Co;2-W  0.44
2000 Okusa MD, Linden J, Huang L, Rieger JM, MacDonald TL, Huynh LP. A(2A) adenosine receptor-mediated inhibition of renal injury and neutrophil adhesion American Journal of Physiology - Renal Physiology. 279: F809-F818. PMID 11053040 DOI: 10.1152/Ajprenal.2000.279.5.F809  0.44
2000 Sullivan GW, Sarembock IJ, Linden J. The role of inflammation in vascular diseases. Journal of Leukocyte Biology. 67: 591-602. PMID 10810997 DOI: 10.1002/Jlb.67.5.591  0.44
1999 Sullivan GW, Linden J, Buster BL, Scheld WM. Neutrophil A2A adenosine receptor inhibits inflammation in a rat model of meningitis: synergy with the type IV phosphodiesterase inhibitor, rolipram. The Journal of Infectious Diseases. 180: 1550-60. PMID 10515815 DOI: 10.1086/315084  0.44
1998 Rosin DL, Robeva A, Woodard RL, Guyenet PG, Linden J. Immunohistochemical localization of adenosine A2A receptors in the rat central nervous system. The Journal of Comparative Neurology. 401: 163-86. PMID 9822147 DOI: 10.1002/(Sici)1096-9861(19981116)401:2<163::Aid-Cne2>3.0.Co;2-D  0.44
1998 Gilchrist A, Mazzoni MR, Dineen B, Dice A, Linden J, Proctor WR, Lupica CR, Dunwiddie TV, Hamm HE. Antagonists of the receptor-G protein interface block Gi-coupled signal transduction. The Journal of Biological Chemistry. 273: 14912-9. PMID 9614095 DOI: 10.1074/Jbc.273.24.14912  0.44
1998 Sullivan GW, Linden J. Role of A2A adenosine receptors in inflammation Drug Development Research. 45: 103-112. DOI: 10.1002/(Sici)1098-2299(199811/12)45:3/4<103::Aid-Ddr4>3.0.Co;2-W  0.48
1997 Jin X, Shepherd RK, Duling BR, Linden J. Inosine binds to A3 adenosine receptors and stimulates mast cell degranulation. The Journal of Clinical Investigation. 100: 2849-57. PMID 9389751 DOI: 10.1172/Jci119833  0.44
1997 Pfister JR, Belardinelli L, Lee G, Lum RT, Milner P, Stanley WC, Linden J, Baker SP, Schreiner G. Synthesis and biological evaluation of the enantiomers of the potent and selective A1-adenosine antagonist 1,3-dipropyl-8-[2-(5,6-epoxynorbonyl)]-xanthine. Journal of Medicinal Chemistry. 40: 1773-8. PMID 9191953 DOI: 10.1021/Jm970013W  0.44
1997 Matherne GP, Linden J, Byford AM, Gauthier NS, Headricr JP. Transgenic A1 adenosine receptor overexpression increases myocardial resistance to ischemia Proceedings of the National Academy of Sciences of the United States of America. 94: 6541-6546. PMID 9177254 DOI: 10.1073/Pnas.94.12.6541  0.44
1997 Fenster MS, Feldman MD, Camarano G, Johnson WH, Ellis M, Linden J, Beller GA. Correlation of adenosine thallium 201 perfusion patterns with markers for inducible ischemia American Heart Journal. 133: 406-412. PMID 9124161 DOI: 10.1016/S0002-8703(97)70181-9  0.44
1996 Shepherd RK, Linden J, Duling BR. Adenosine-induced vasoconstriction in vivo. Role of the mast cell and A3 adenosine receptor. Circulation Research. 78: 627-34. PMID 8635220 DOI: 10.1161/01.Res.78.4.627  0.44
1995 Cothran DL, Lloyd TR, Taylor H, Linden J, Matherne GP. Ontogeny of rat myocardial A1 adenosine receptors. Biology of the Neonate. 68: 111-8. PMID 8534770 DOI: 10.1159/000244226  0.44
1994 McLaughlin DP, Beller GA, Linden J, Ayers CR, Ripley ML, Taylor H, Watson DD, Feldman MD. Hemodynamic and metabolic correlates of dipyridamole-induced myocardial thallium-201 perfusion abnormalities in multivessel coronary artery disease. The American Journal of Cardiology. 73: 1159-64. PMID 8203332 DOI: 10.1016/0002-9149(94)90174-0  0.44
1994 Sawmiller DR, Linden J, Berne RM. Effects of xanthine amine congener on hypoxic coronary resistance and venous and epicardial adenosine concentrations. Cardiovascular Research. 28: 604-9. PMID 8025903 DOI: 10.1093/Cvr/28.5.604  0.44
1993 Musser B, Morgan ME, Leid M, Murray TF, Linden J, Vestal RE. Species comparison of adenosine and beta-adrenoceptors in mammalian atrial and ventricular myocardium. European Journal of Pharmacology. 246: 105-11. PMID 8397091 DOI: 10.1016/0922-4106(93)90086-O  0.44
1992 Tucker AL, Linden J, Robeva AS, D'Angelo DD, Lynch KR. Cloning and expression of a bovine adenosine A1 receptor cDNA. Febs Letters. 297: 107-11. PMID 1551415 DOI: 10.1016/0014-5793(92)80338-H  0.44
1992 Linden J, Vandenhoff GE, Taylor D, Finkelstein GL. Solid phase enzyme immunoassay of cyclic adenosine 3',5'-monophosphate. Effect of coating strategy upon assay performance in comparison with radioimmunoassay. Journal of Immunological Methods. 151: 209-16. PMID 1321200 DOI: 10.1016/0022-1759(92)90119-E  0.44
1991 Linden J, Tucker AL, Lynch KR. Molecular cloning of adenosine A1 and A2 receptors Trends in Pharmacological Sciences. 12: 326-328. PMID 1949201 DOI: 10.1016/0165-6147(91)90589-K  0.44
1991 Linden J, Prater MR, Sullivan GW, Johns RA, Patel A. Contamination of adenosine deaminase by superoxide dismutase. Stabilization of endothelium-derived relaxing factor. Biochemical Pharmacology. 41: 273-9. PMID 1846547 DOI: 10.1016/0006-2952(91)90486-O  0.48
1991 Chevalier RL, Garmey M, Scarborough RM, Linden J, Gomez RA, Peach MJ, Carey RM. Inhibition of ANP clearance receptors and endopeptidase 24.11 in maturing rats American Journal of Physiology - Regulatory Integrative and Comparative Physiology. 260. PMID 1647702 DOI: 10.1152/Ajpregu.1991.260.6.R1218  0.44
1990 Greenfield LJ, Hackett JT, Linden J. Xenopus oocyte K+ current. II. Adenylyl cyclase-linked receptors on follicle cells. The American Journal of Physiology. 259: C784-91. PMID 2173413 DOI: 10.1152/Ajpcell.1990.259.5.C784  0.44
1990 Greenfield LJ, Hackett JT, Linden J. Xenopus oocyte K+ current. I. FSH and adenosine stimulate follicle cell-dependent currents. The American Journal of Physiology. 259: C775-83. PMID 2122736 DOI: 10.1152/Ajpcell.1990.259.5.C775  0.44
1990 Weikel CS, Spann CL, Chambers CP, Crane JK, Linden J, Hewlett EL. Phorbol esters enhance the cyclic GMP response of T84 cells to the heat-stable enterotoxin of Escherichia coli (STa) Infection and Immunity. 58: 1402-1407. PMID 1969850  0.44
1990 Greenfield LJ, Hackett JT, Linden J. Xenopus oocyte K+ current. III. Phorbol esters and pH regulate current at gap junctions. The American Journal of Physiology. 259: C792-800. PMID 1700623 DOI: 10.1152/Ajpcell.1990.259.5.C792  0.44
1989 Belardinelli L, Linden J, Berne RM. The cardiac effects of adenosine. Progress in Cardiovascular Diseases. 32: 73-97. PMID 2664879 DOI: 10.1016/0033-0620(89)90015-7  0.44
1982 Belardinelli L, Fenton RA, West A, Linden J, Althaus JS, Berne RM. Extracellular action of adenosine and the antagonism by aminophylline on the atrioventricular conduction of isolated perfused guinea pig and rat hearts. Circulation Research. 51: 569-79. PMID 6291799 DOI: 10.1161/01.Res.51.5.569  0.44
1982 Belardinelli L, Vogel S, Linden J, Berne RM. Antiadrenergic action of adenosine on ventricular myocardium in embryonic chick hearts. Journal of Molecular and Cellular Cardiology. 14: 291-4. PMID 6290675 DOI: 10.1016/0022-2828(82)90207-3  0.44
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