| Year |
Citation |
Score |
| 2023 |
Hahn KM, Itano MS, Loew LM, Vitriol EA. Celebrating the creative scientific life of Ken Jacobson. Biophysical Journal. PMID 37643609 DOI: 10.1016/j.bpj.2023.08.013 |
0.636 |
|
| 2023 |
Pimenta FM, Huh J, Guzman B, Amanah D, Marston DJ, Pinkin NK, Danuser G, Hahn KM. Rho MultiBinder, a fluorescent biosensor that reports the activity of multiple GTPases. Biophysical Journal. PMID 37085995 DOI: 10.1016/j.bpj.2023.04.020 |
0.341 |
|
| 2021 |
Chadelle L, Liu J, Choesmel-Cadamuro V, Karginov AV, Froment C, Burlet-Schiltz O, Gandarillas S, Barreira Y, Segura C, Van Den Berghe L, Czaplicki G, Van Acker N, Dalenc F, Franchet C, Hahn KM, et al. PKCθ-mediated serine/threonine phosphorylations of FAK govern adhesion and protrusion dynamics within the lamellipodia of migrating breast cancer cells. Cancer Letters. PMID 34826547 DOI: 10.1016/j.canlet.2021.11.026 |
0.31 |
|
| 2021 |
Bianchi-Smiraglia A, Wolff DW, Marston DJ, Deng Z, Han Z, Moparthy S, Wombacher RM, Mussell AL, Shen S, Chen J, Yun DH, O'Brien Cox A, Furdui CM, Hurley E, Feltri ML, ... ... Hahn KM, et al. Regulation of local GTP availability controls RAC1 activity and cell invasion. Nature Communications. 12: 6091. PMID 34667203 DOI: 10.1038/s41467-021-26324-6 |
0.329 |
|
| 2021 |
Liu B, Stone OJ, Pablo M, Herron JC, Nogueira AT, Dagliyan O, Grimm JB, Lavis LD, Elston TC, Hahn KM. Biosensors based on peptide exposure show single molecule conformations in live cells. Cell. PMID 34637702 DOI: 10.1016/j.cell.2021.09.026 |
0.797 |
|
| 2020 |
Allen RJ, Welch C, Pankow N, Hahn KM, Elston TC. Stochastic Methods for Inferring States of Cell Migration. Frontiers in Physiology. 11: 822. PMID 32754053 DOI: 10.3389/Fphys.2020.00822 |
0.648 |
|
| 2020 |
Stone OJ, Pankow N, Liu B, Sharma VP, Eddy RJ, Wang H, Putz AT, Teets FD, Kuhlman B, Condeelis JS, Hahn KM. Author Correction: Optogenetic control of cofilin and αTAT in living cells using Z-lock. Nature Chemical Biology. PMID 32694868 DOI: 10.1038/S41589-020-0614-X |
0.767 |
|
| 2020 |
Liu B, Marston DJ, Hahn KM. Engineering Optogenetic Protein Analogs. Methods in Molecular Biology (Clifton, N.J.). 2173: 113-126. PMID 32651913 DOI: 10.1007/978-1-0716-0755-8_7 |
0.469 |
|
| 2020 |
Marston DJ, Vilela M, Huh J, Ren J, Azoitei ML, Glekas G, Danuser G, Sondek J, Hahn KM. Multiplexed GTPase and GEF biosensor imaging enables network connectivity analysis. Nature Chemical Biology. PMID 32424303 DOI: 10.1038/S41589-020-0542-9 |
0.443 |
|
| 2020 |
Nelsen E, Hobson CM, Kern ME, Hsiao JP, O'Brien Iii ET, Watanabe T, Condon BM, Boyce M, Grinstein S, Hahn KM, Falvo MR, Superfine R. Combined Atomic Force Microscope and Volumetric Light Sheet System for Correlative Force and Fluorescence Mechanobiology Studies. Scientific Reports. 10: 8133. PMID 32424215 DOI: 10.1038/S41598-020-65205-8 |
0.311 |
|
| 2020 |
Popkova A, Stone OJ, Chen L, Qin X, Liu C, Liu J, Belguise K, Montell DJ, Hahn KM, Rauzi M, Wang X. A Cdc42-mediated supracellular network drives polarized forces and Drosophila egg chamber extension. Nature Communications. 11: 1921. PMID 32317641 DOI: 10.1038/S41467-020-15593-2 |
0.77 |
|
| 2020 |
Pablo M, Liu B, Stone O, Dagliyan O, Elston TC, Hahn KM. Binder/Tag: A Versatile Approach to Probe and Control the Conformational Changes of Individual Molecules in Living Cells Biophysical Journal. 118: 167a. DOI: 10.1016/J.Bpj.2019.11.1025 |
0.783 |
|
| 2019 |
Teets FD, Watanabe T, Hahn KM, Kuhlman B. A computational protocol for regulating protein binding reactions with a light sensitive protein dimer. Journal of Molecular Biology. PMID 31887287 DOI: 10.1016/J.Jmb.2019.12.033 |
0.399 |
|
| 2019 |
Stone OJ, Pankow N, Liu B, Sharma VP, Eddy RJ, Wang H, Putz AT, Teets FD, Kuhlman B, Condeelis JS, Hahn KM. Optogenetic control of cofilin and αTAT in living cells using Z-lock. Nature Chemical Biology. 15: 1183-1190. PMID 31740825 DOI: 10.1038/S41589-019-0405-4 |
0.808 |
|
| 2019 |
O'Shaughnessy EC, Stone OJ, LaFosse PK, Azoitei ML, Tsygankov D, Heddleston JM, Legant WR, Wittchen ES, Burridge K, Elston TC, Betzig E, Chew TL, Adalsteinsson D, Hahn KM. Software for lattice light-sheet imaging of FRET biosensors, illustrated with a new Rap1 biosensor. The Journal of Cell Biology. PMID 31444239 DOI: 10.1083/Jcb.201903019 |
0.782 |
|
| 2019 |
Azoitei ML, Noh J, Marston DJ, Roudot P, Marshall CB, Daugird TA, Lisanza SL, Sandí MJ, Ikura M, Sondek J, Rottapel R, Hahn KM, Danuser G. Spatiotemporal dynamics of GEF-H1 activation controlled by microtubule- and Src-mediated pathways. The Journal of Cell Biology. PMID 31420453 DOI: 10.1083/Jcb.201812073 |
0.353 |
|
| 2019 |
Hahn KM. An 'on' switch for proteins. Nature. 569: 490-491. PMID 31114074 DOI: 10.1038/D41586-019-01394-1 |
0.367 |
|
| 2019 |
Dagliyan O, Dokholyan NV, Hahn KM. Engineering proteins for allosteric control by light or ligands. Nature Protocols. PMID 31076662 DOI: 10.1038/S41596-019-0165-3 |
0.793 |
|
| 2019 |
MacNevin CJ, Watanabe T, Weitzman M, Gulyani A, Fuehrer S, Pinkin NK, Tian X, Liu F, Jin J, Hahn KM. Membrane-permeant, environment-sensitive dyes generate biosensors within living cells. Journal of the American Chemical Society. PMID 30994345 DOI: 10.1021/Jacs.8B09841 |
0.42 |
|
| 2019 |
Dagliyan O, Hahn KM. Controlling protein conformation with light. Current Opinion in Structural Biology. 57: 17-22. PMID 30849716 DOI: 10.1016/J.Sbi.2019.01.012 |
0.754 |
|
| 2019 |
Marston DJ, Anderson KL, Swift MF, Rougie M, Page C, Hahn KM, Volkmann N, Hanein D. High Rac1 activity is functionally translated into cytosolic structures with unique nanoscale cytoskeletal architecture. Proceedings of the National Academy of Sciences of the United States of America. PMID 30630946 DOI: 10.1073/Pnas.1808830116 |
0.391 |
|
| 2019 |
Dokholyan NV, Dagliyan O, Hahn KM. Control of Cellular Networks by Structural Disorder Biophysical Journal. 116: 490a. DOI: 10.1016/J.Bpj.2018.11.2645 |
0.723 |
|
| 2018 |
Dagliyan O, Krokhotin A, Ozkan-Dagliyan I, Deiters A, Der CJ, Hahn KM, Dokholyan NV. Computational design of chemogenetic and optogenetic split proteins. Nature Communications. 9: 4042. PMID 30279442 DOI: 10.1038/S41467-018-06531-4 |
0.782 |
|
| 2018 |
Ma X, Dagliyan O, Hahn KM, Danuser G. Profiling cellular morphodynamics by spatiotemporal spectrum decomposition. Plos Computational Biology. 14: e1006321. PMID 30071020 DOI: 10.1371/Journal.Pcbi.1006321 |
0.728 |
|
| 2018 |
Zhurikhina A, Qi T, Hahn KM, Elston TC, Tsygankov D. EdgeProps: A Computational Platform for Correlative Analysis of Cell Dynamics and Near-Edge Protein Activity. Methods in Molecular Biology (Clifton, N.J.). 1821: 47-56. PMID 30062404 DOI: 10.1007/978-1-4939-8612-5_4 |
0.441 |
|
| 2018 |
Woroniuk A, Porter A, White G, Newman DT, Diamantopoulou Z, Waring T, Rooney C, Strathdee D, Marston DJ, Hahn KM, Sansom OJ, Zech T, Malliri A. STEF/TIAM2-mediated Rac1 activity at the nuclear envelope regulates the perinuclear actin cap. Nature Communications. 9: 2124. PMID 29844364 DOI: 10.1038/S41467-018-04404-4 |
0.342 |
|
| 2018 |
Tajadura-Ortega V, Garg R, Allen R, Owczarek C, Bright MD, Kean S, Mohd-Noor A, Grigoriadis A, Elston TC, Hahn KM, Ridley AJ. An RNAi screen of Rho signalling networks identifies RhoH as a regulator of Rac1 in prostate cancer cell migration. Bmc Biology. 16: 29. PMID 29510700 DOI: 10.1186/S12915-018-0489-4 |
0.342 |
|
| 2018 |
Yumerefendi H, Wang H, Dickinson DJ, Lerner A, Malkus P, Goldstein B, Hahn K, Kuhlman B. Light-dependent cytoplasmic recruitment enhances the dynamic range of a nuclear import photoswitch. Chembiochem : a European Journal of Chemical Biology. PMID 29446199 DOI: 10.1002/Cbic.201700681 |
0.394 |
|
| 2018 |
van Haren J, Charafeddine RA, Ettinger A, Wang H, Hahn KM, Wittmann T. Local control of intracellular microtubule dynamics by EB1 photodissociation. Nature Cell Biology. PMID 29379139 DOI: 10.1038/S41556-017-0028-5 |
0.42 |
|
| 2018 |
van Haren J, Charafeddine R, Ettinger A, Wang H, Hahn KM, Wittmann T. Optical Control of EB1 Reveals Local Functions of the Microtubule +TIP Complex During Cell Migration and Division Biophysical Journal. 114: 382a. DOI: 10.1016/J.Bpj.2017.11.2115 |
0.316 |
|
| 2018 |
Liu B, Stone O, Dagliyan O, Hahn K. Probe the Conformational Changes of Individual Molecules in Living Cells Biophysical Journal. 114: 21a. DOI: 10.1016/J.Bpj.2017.11.158 |
0.777 |
|
| 2017 |
Takano T, Wu M, Nakamuta S, Naoki H, Ishizawa N, Namba T, Watanabe T, Xu C, Hamaguchi T, Yura Y, Amano M, Hahn KM, Kaibuchi K. Discovery of long-range inhibitory signaling to ensure single axon formation. Nature Communications. 8: 33. PMID 28652571 DOI: 10.1038/S41467-017-00044-2 |
0.323 |
|
| 2017 |
Herrington KA, Trinh AL, Dang C, O'Shaughnessy E, Hahn KM, Gratton E, Digman MA, Sütterlin C. Spatial analysis of Cdc42 activity reveals a role for plasma membrane-associated Cdc42 in centrosome regulation. Molecular Biology of the Cell. PMID 28539409 DOI: 10.1091/Mbc.E16-09-0665 |
0.394 |
|
| 2017 |
Ye F, Yang C, Kim J, MacNevin CJ, Hahn KM, Park D, Ginsberg MH, Kim C. Epigallocatechin gallate has pleiotropic effects on transmembrane signaling by altering the embedding of transmembrane domains. The Journal of Biological Chemistry. PMID 28487468 DOI: 10.1074/Jbc.C117.787309 |
0.369 |
|
| 2017 |
Dagliyan O, Karginov AV, Yagishita S, Gale ME, Wang H, DerMardirossian C, Wells CM, Dokholyan NV, Kasai H, Hahn KM. Engineering Pak1 allosteric switches. Acs Synthetic Biology. PMID 28365983 DOI: 10.1021/Acssynbio.6B00359 |
0.788 |
|
| 2017 |
Woodham EF, Paul NR, Tyrrell B, Spence HJ, Swaminathan K, Scribner MR, Giampazolias E, Hedley A, Clark W, Kage F, Marston DJ, Hahn KM, Tait SW, Larue L, Brakebusch CH, et al. Coordination by Cdc42 of Actin, Contractility, and Adhesion for Melanoblast Movement in Mouse Skin. Current Biology : Cb. PMID 28238662 DOI: 10.1016/J.Cub.2017.01.033 |
0.345 |
|
| 2017 |
Stone OJ, Kaul N, Wang H, Sharma VP, Eddy RJ, Condeelis JS, Hahn KM. Zlock, a Broadly Applicable Optogenetic Method, Controls Cofilin in Living Cells Biophysical Journal. 112: 134a-135a. DOI: 10.1016/J.Bpj.2016.11.745 |
0.825 |
|
| 2017 |
Kaul N, Wang H, Dagliyan O, Hahn KM. An Optogenetic Approach to Control Microtubule Acetylation in Living Cells Biophysical Journal. 112: 563a. DOI: 10.1016/J.Bpj.2016.11.3034 |
0.755 |
|
| 2017 |
Ma X, Dagliyan O, Hahn K, Danuser G. Morphodynamic Profiling of Cell Protrusion Based on Spatiotemporal Spectrum Decomposition and Unsupervised Clustering Biophysical Journal. 112: 45a. DOI: 10.1016/J.Bpj.2016.11.285 |
0.729 |
|
| 2017 |
Azoitei ML, Noh J, Sandi MJ, Roudot P, Rottapel R, Danuser G, Hahn KM. Novel Biosensor Design Reveals the Role and Regulation of GEF-H1 in Cell Migration Biophysical Journal. 112: 461a. DOI: 10.1016/J.Bpj.2016.11.2471 |
0.378 |
|
| 2016 |
Dagliyan O, Tarnawski M, Chu PH, Shirvanyants D, Schlichting I, Dokholyan NV, Hahn KM. Engineering extrinsic disorder to control protein activity in living cells. Science (New York, N.Y.). 354: 1441-1444. PMID 27980211 DOI: 10.1126/Science.Aah3404 |
0.818 |
|
| 2016 |
Wang H, Hahn KM. LOVTRAP: A Versatile Method to Control Protein Function with Light. Current Protocols in Cell Biology. 73: 21.10.1-21.10.14. PMID 27906450 DOI: 10.1002/Cpcb.12 |
0.361 |
|
| 2016 |
Nguyen TT, Park WS, Park BO, Kim CY, Oh Y, Kim JM, Choi H, Kyung T, Kim CH, Lee G, Hahn KM, Meyer T, Heo WD. PLEKHG3 enhances polarized cell migration by activating actin filaments at the cell front. Proceedings of the National Academy of Sciences of the United States of America. PMID 27555588 DOI: 10.1073/Pnas.1604720113 |
0.416 |
|
| 2016 |
Hodgson L, Spiering D, Sabouri-Ghomi M, Dagliyan O, DerMardirossian C, Danuser G, Hahn KM. FRET binding antenna reports spatiotemporal dynamics of GDI-Cdc42 GTPase interactions. Nature Chemical Biology. PMID 27501396 DOI: 10.1038/Nchembio.2145 |
0.746 |
|
| 2016 |
Wang H, Vilela M, Winkler A, Tarnawski M, Schlichting I, Yumerefendi H, Kuhlman B, Liu R, Danuser G, Hahn KM. LOVTRAP: an optogenetic system for photoinduced protein dissociation. Nature Methods. PMID 27427858 DOI: 10.1038/Nmeth.3926 |
0.41 |
|
| 2016 |
Yumerefendi H, Lerner AM, Zimmerman SP, Hahn K, Bear JE, Strahl BD, Kuhlman B. Light-induced nuclear export reveals rapid dynamics of epigenetic modifications. Nature Chemical Biology. PMID 27089030 DOI: 10.1038/Nchembio.2068 |
0.607 |
|
| 2016 |
MacNevin CJ, Toutchkine A, Marston DJ, Hsu CW, Tsygankov D, Li L, Liu B, Qi T, Nguyen DV, Hahn KM. Ratiometric imaging using a single dye enables simultaneous visualization of Rac1 and Cdc42 activation. Journal of the American Chemical Society. PMID 26863024 DOI: 10.1021/Jacs.5B09764 |
0.635 |
|
| 2016 |
Gentry LR, Karginov AV, Hahn KM, Der CJ. Characterization of an Engineered Src Kinase to Study Src Signaling and Biology. Methods in Molecular Biology (Clifton, N.J.). 1360: 157-67. PMID 26501909 DOI: 10.1007/978-1-4939-3073-9_12 |
0.396 |
|
| 2016 |
Marston DJ, Vilela M, Glekas G, Danuser G, Sondek J, Hahn KM. Simultaneous Imaging of Rho GTPase and RhoGEF Activation using Novel GEF Biosensors Reveals Relationships between GEF and GTPase Activation in Cell Motility Biophysical Journal. 110: 333a. DOI: 10.1016/J.Bpj.2015.11.1791 |
0.47 |
|
| 2016 |
Stone OJ, Wang H, Sharma VP, Eddy RJ, Liu R, Condeelis JS, Hahn KM. Rational Design of a Photoactivatable Cofilin Analog using a Novel Lov-Binding Protein Biophysical Journal. 110: 317a. DOI: 10.1016/J.Bpj.2015.11.1701 |
0.81 |
|
| 2015 |
Yi JJ, Berrios J, Newbern JM, Snider WD, Philpot BD, Hahn KM, Zylka MJ. An Autism-Linked Mutation Disables Phosphorylation Control of UBE3A. Cell. 162: 795-807. PMID 26255772 DOI: 10.1016/J.Cell.2015.06.045 |
0.726 |
|
| 2015 |
Yumerefendi H, Dickinson DJ, Wang H, Zimmerman SP, Bear JE, Goldstein B, Hahn K, Kuhlman B. Control of Protein Activity and Cell Fate Specification via Light-Mediated Nuclear Translocation. Plos One. 10: e0128443. PMID 26083500 DOI: 10.1371/Journal.Pone.0128443 |
0.669 |
|
| 2015 |
Yi JJ, Berrios J, Newbern JM, Snider WD, Philpot BD, Hahn KM, Zylka MJ. An Autism-Linked Mutation Disables Phosphorylation Control of UBE3A Cell. 162: 795-807. DOI: 10.1016/j.cell.2015.06.045 |
0.664 |
|
| 2014 |
Slattery SD, Hahn KM. A High-Content Assay for Biosensor Validation and for Examining Stimuli that Affect Biosensor Activity. Current Protocols in Cell Biology / Editorial Board, Juan S. Bonifacino ... [Et Al.]. 65: 14.15.1-14.15.31. PMID 25447074 DOI: 10.1002/0471143030.Cb1415S65 |
0.395 |
|
| 2014 |
Weitzman M, Hahn KM. Optogenetic approaches to cell migration and beyond. Current Opinion in Cell Biology. 30: 112-20. PMID 25216352 DOI: 10.1016/J.Ceb.2014.08.004 |
0.401 |
|
| 2014 |
Chu PH, Tsygankov D, Berginski ME, Dagliyan O, Gomez SM, Elston TC, Karginov AV, Hahn KM. Engineered kinase activation reveals unique morphodynamic phenotypes and associated trafficking for Src family isoforms. Proceedings of the National Academy of Sciences of the United States of America. 111: 12420-5. PMID 25118278 DOI: 10.1073/Pnas.1404487111 |
0.784 |
|
| 2014 |
Tsygankov D, Chu PH, Chen H, Elston TC, Hahn KM. User-friendly tools for quantifying the dynamics of cellular morphology and intracellular protein clusters. Methods in Cell Biology. 123: 409-27. PMID 24974040 DOI: 10.1016/B978-0-12-420138-5.00022-7 |
0.541 |
|
| 2014 |
Yi JJ, Wang H, Vilela M, Danuser G, Hahn KM. Manipulation of endogenous kinase activity in living cells using photoswitchable inhibitory peptides. Acs Synthetic Biology. 3: 788-95. PMID 24905630 DOI: 10.1021/Sb5001356 |
0.628 |
|
| 2014 |
Karginov AV, Hahn KM, Deiters A. Optochemical activation of kinase function in live cells. Methods in Molecular Biology (Clifton, N.J.). 1148: 31-43. PMID 24718793 DOI: 10.1007/978-1-4939-0470-9_3 |
0.404 |
|
| 2014 |
Karginov AV, Tsygankov D, Berginski M, Chu PH, Trudeau ED, Yi JJ, Gomez S, Elston TC, Hahn KM. Dissecting motility signaling through activation of specific Src-effector complexes. Nature Chemical Biology. 10: 286-90. PMID 24609359 DOI: 10.1038/Nchembio.1477 |
0.72 |
|
| 2014 |
Hinde E, Yokomori K, Gaus K, Hahn KM, Gratton E. Fluctuation-based imaging of nuclear Rac1 activation by protein oligomerisation. Scientific Reports. 4: 4219. PMID 24573109 DOI: 10.1038/Srep04219 |
0.402 |
|
| 2014 |
Tsygankov D, Bilancia CG, Vitriol EA, Hahn KM, Peifer M, Elston TC. CellGeo: a computational platform for the analysis of shape changes in cells with complex geometries. The Journal of Cell Biology. 204: 443-60. PMID 24493591 DOI: 10.1083/Jcb.201306067 |
0.744 |
|
| 2014 |
Khalil BD, Hanna S, Saykali BA, El-Sitt S, Nasrallah A, Marston D, El-Sabban M, Hahn KM, Symons M, El-Sibai M. The regulation of RhoA at focal adhesions by StarD13 is important for astrocytoma cell motility. Experimental Cell Research. 321: 109-22. PMID 24333506 DOI: 10.1016/J.Yexcr.2013.11.023 |
0.434 |
|
| 2014 |
Allen RJ, Tsygankov D, Zawistowski JS, Elston TC, Hahn KM. Automated line scan analysis to quantify biosensor activity at the cell edge. Methods (San Diego, Calif.). 66: 162-7. PMID 23994242 DOI: 10.1016/J.Ymeth.2013.08.025 |
0.387 |
|
| 2014 |
Karginov AV, Tsygankov D, Berginski M, Chu P, Trudeau ED, Yi JJ, Gomez S, Elston TC, Hahn KM. Correction: Corrigendum: Dissecting motility signaling through activation of specific Src-effector complexes Nature Chemical Biology. 10: 692-692. DOI: 10.1038/Nchembio0814-692C |
0.65 |
|
| 2013 |
Zawistowski JS, Sabouri-Ghomi M, Danuser G, Hahn KM, Hodgson L. A RhoC biosensor reveals differences in the activation kinetics of RhoA and RhoC in migrating cells. Plos One. 8: e79877. PMID 24224016 DOI: 10.1371/Journal.Pone.0079877 |
0.405 |
|
| 2013 |
Kummer L, Hsu CW, Dagliyan O, MacNevin C, Kaufholz M, Zimmermann B, Dokholyan NV, Hahn KM, Plückthun A. Knowledge-based design of a biosensor to quantify localized ERK activation in living cells. Chemistry & Biology. 20: 847-56. PMID 23790495 DOI: 10.1016/J.Chembiol.2013.04.016 |
0.82 |
|
| 2013 |
Rao MV, Chu PH, Hahn KM, Zaidel-Bar R. An optogenetic tool for the activation of endogenous diaphanous-related formins induces thickening of stress fibers without an increase in contractility. Cytoskeleton (Hoboken, N.J.). 70: 394-407. PMID 23677607 DOI: 10.1002/Cm.21115 |
0.494 |
|
| 2013 |
Konze KD, Ma A, Li F, Barsyte-Lovejoy D, Parton T, Macnevin CJ, Liu F, Gao C, Huang XP, Kuznetsova E, Rougie M, Jiang A, Pattenden SG, Norris JL, James LI, ... ... Hahn KM, et al. An orally bioavailable chemical probe of the Lysine Methyltransferases EZH2 and EZH1. Acs Chemical Biology. 8: 1324-34. PMID 23614352 DOI: 10.1021/Cb400133J |
0.346 |
|
| 2013 |
Dagliyan O, Shirvanyants D, Karginov AV, Ding F, Fee L, Chandrasekaran SN, Freisinger CM, Smolen GA, Huttenlocher A, Hahn KM, Dokholyan NV. Rational design of a ligand-controlled protein conformational switch. Proceedings of the National Academy of Sciences of the United States of America. 110: 6800-4. PMID 23569285 DOI: 10.1073/Pnas.1218319110 |
0.808 |
|
| 2013 |
Samson T, van Buul JD, Kroon J, Welch C, Bakker EN, Matlung HL, van den Berg TK, Sharek L, Doerschuk C, Hahn K, Burridge K. The guanine-nucleotide exchange factor SGEF plays a crucial role in the formation of atherosclerosis. Plos One. 8: e55202. PMID 23372835 DOI: 10.1371/Journal.Pone.0055202 |
0.691 |
|
| 2013 |
MacNevin CJ, Gremyachinskiy D, Hsu CW, Li L, Rougie M, Davis TT, Hahn KM. Environment-sensing merocyanine dyes for live cell imaging applications. Bioconjugate Chemistry. 24: 215-23. PMID 23297747 DOI: 10.1021/Bc3005073 |
0.606 |
|
| 2013 |
Vilela M, Halidi N, Besson S, Elliott H, Hahn K, Tytell J, Danuser G. Fluctuation analysis of activity biosensor images for the study of information flow in signaling pathways. Methods in Enzymology. 519: 253-76. PMID 23280114 DOI: 10.1016/B978-0-12-405539-1.00009-9 |
0.372 |
|
| 2013 |
Hinde E, Digman MA, Hahn KM, Gratton E. Millisecond spatiotemporal dynamics of FRET biosensors by the pair correlation function and the phasor approach to FLIM. Proceedings of the National Academy of Sciences of the United States of America. 110: 135-40. PMID 23248275 DOI: 10.1073/Pnas.1211882110 |
0.393 |
|
| 2013 |
Chu P, Karginov AV, Tsygankov DM, Berginski ME, Gomez SM, Elston TC, Hahn KM. New Tools for Activation of Src Family Isoforms In Vivo Demonstrate Specific Roles for Each Isoform in Cell Motility Biophysical Journal. 104: 161a. DOI: 10.1016/J.Bpj.2012.11.907 |
0.609 |
|
| 2013 |
Karginov AV, Tsygangov D, Berginski ME, Trudeau ED, Chu P, Yi JJ, Gomez SM, Elston TC, Hahn KM. Engineered Manipulation of Signaling Networks: Control of Kinase Activation and Interactions Dissects Parallel Src Pathways Biophysical Journal. 104: 161a. DOI: 10.1016/J.Bpj.2012.11.906 |
0.718 |
|
| 2013 |
O-Shaughnessy E, Elston TC, Hahn KM. Development of a Rap1 Flare.Dc Biosensor for Quantitative Measurement of Spatio-Temporal Dynamics In Vivo Biophysical Journal. 104: 160a-161a. DOI: 10.1016/J.Bpj.2012.11.905 |
0.433 |
|
| 2013 |
Chu P, Karginov AV, Shirvanyants DG, Dokholyan NV, Hahn KM. Generation of a Light Inhibited Src Kinase through Insertion of LOV into the Catalytic Domain Biophysical Journal. 104: 679a. DOI: 10.1016/J.Bpj.2012.11.3750 |
0.679 |
|
| 2013 |
Wang H, Vilela M, Danuser G, Winkler A, Hartmann E, Schlichting I, Liu R, Hahn KM. Lov-Trap: A Broadly Applicable, Genetically Encoded System to Control Protein Activity with Light through Controlled Sequestration at Membranes Biophysical Journal. 104: 214a-215a. DOI: 10.1016/J.Bpj.2012.11.1213 |
0.442 |
|
| 2012 |
Collins C, Guilluy C, Welch C, O'Brien ET, Hahn K, Superfine R, Burridge K, Tzima E. Localized tensional forces on PECAM-1 elicit a global mechanotransduction response via the integrin-RhoA pathway. Current Biology : Cb. 22: 2087-94. PMID 23084990 DOI: 10.1016/J.Cub.2012.08.051 |
0.715 |
|
| 2012 |
Lungu OI, Hallett RA, Choi EJ, Aiken MJ, Hahn KM, Kuhlman B. Designing photoswitchable peptides using the AsLOV2 domain. Chemistry & Biology. 19: 507-17. PMID 22520757 DOI: 10.1016/J.Chembiol.2012.02.006 |
0.783 |
|
| 2012 |
Hinde E, Digman MA, Welch C, Hahn KM, Gratton E. Biosensor Förster resonance energy transfer detection by the phasor approach to fluorescence lifetime imaging microscopy. Microscopy Research and Technique. 75: 271-81. PMID 21858900 DOI: 10.1002/Jemt.21054 |
0.62 |
|
| 2012 |
Gulyani A, Vitriol E, Allen R, Wu J, Gremyachinskiy D, Lewis S, Dewar B, Graves LM, Kay BK, Kuhlman B, Elston T, Hahn KM. Erratum: Corrigendum: A biosensor generated via high-throughput screening quantifies cell edge Src dynamics Nature Chemical Biology. 8: 737-737. DOI: 10.1038/Nchembio0812-737D |
0.706 |
|
| 2012 |
Hodgson L, Spiering D, Sabouri M, Der Mardirossian C, Danuser G, Hahn K. New Advances in Live-cell Imaging: Multiplexed Protein Activity Measurements and Correlational Studies of Rho GTPase Regulation in Living Cells. Microscopy and Microanalysis. 18: 130-131. DOI: 10.1017/S1431927612002504 |
0.42 |
|
| 2012 |
Lungu OI, Hallett RA, Choi EJ, Aiken MJ, Hahn KM, Kuhlman BA. Erratum: Designing photoswitchable peptides using the AsLOV2 domain (Chemistry and Biology (2012) 19 (507-517)) Chemistry & Biology. 19. DOI: 10.1016/J.Chembiol.2012.07.009 |
0.754 |
|
| 2011 |
Karginov AV, Hahn KM. Allosteric activation of kinases: design and application of RapR kinases. Current Protocols in Cell Biology / Editorial Board, Juan S. Bonifacino ... [Et Al.]. Unit 14.13.. PMID 22161545 DOI: 10.1002/0471143030.Cb1413S53 |
0.366 |
|
| 2011 |
Welch CM, Elliott H, Danuser G, Hahn KM. Imaging the coordination of multiple signalling activities in living cells. Nature Reviews. Molecular Cell Biology. 12: 749-56. PMID 22016058 DOI: 10.1038/Nrm3212 |
0.641 |
|
| 2011 |
Jha RK, Wu YI, Zawistowski JS, MacNevin C, Hahn KM, Kuhlman B. Redesign of the PAK1 autoinhibitory domain for enhanced stability and affinity in biosensor applications. Journal of Molecular Biology. 413: 513-22. PMID 21888918 DOI: 10.1016/J.Jmb.2011.08.022 |
0.355 |
|
| 2011 |
Berginski ME, Vitriol EA, Hahn KM, Gomez SM. High-resolution quantification of focal adhesion spatiotemporal dynamics in living cells. Plos One. 6: e22025. PMID 21779367 DOI: 10.1371/Journal.Pone.0022025 |
0.752 |
|
| 2011 |
Gulyani A, Vitriol E, Allen R, Wu J, Gremyachinskiy D, Lewis S, Dewar B, Graves LM, Kay BK, Kuhlman B, Elston T, Hahn KM. A biosensor generated via high-throughput screening quantifies cell edge Src dynamics. Nature Chemical Biology. 7: 437-44. PMID 21666688 DOI: 10.1038/Nchembio.585 |
0.757 |
|
| 2011 |
Shadpour H, Zawistowski JS, Herman A, Hahn K, Allbritton NL. Patterning pallet arrays for cell selection based on high-resolution measurements of fluorescent biosensors. Analytica Chimica Acta. 696: 101-7. PMID 21621038 DOI: 10.1016/J.Aca.2011.04.012 |
0.397 |
|
| 2011 |
Wu YI, Wang X, He L, Montell D, Hahn KM. Spatiotemporal control of small GTPases with light using the LOV domain. Methods in Enzymology. 497: 393-407. PMID 21601095 DOI: 10.1016/B978-0-12-385075-1.00016-0 |
0.482 |
|
| 2011 |
Helfand BT, Mendez MG, Murthy SN, Shumaker DK, Grin B, Mahammad S, Aebi U, Wedig T, Wu YI, Hahn KM, Inagaki M, Herrmann H, Goldman RD. Vimentin organization modulates the formation of lamellipodia. Molecular Biology of the Cell. 22: 1274-89. PMID 21346197 DOI: 10.1091/Mbc.E10-08-0699 |
0.395 |
|
| 2011 |
Karginov AV, Zou Y, Shirvanyants D, Kota P, Dokholyan NV, Young DD, Hahn KM, Deiters A. Light regulation of protein dimerization and kinase activity in living cells using photocaged rapamycin and engineered FKBP. Journal of the American Chemical Society. 133: 420-3. PMID 21162531 DOI: 10.1021/Ja109630V |
0.623 |
|
| 2011 |
Hahn K. New Tools to Peek and Poke at Rapid Signaling in Living Systems Biophysical Journal. 100: 3-3. DOI: 10.1016/J.Bpj.2010.12.2219 |
0.407 |
|
| 2010 |
Hahn KM, Kuhlman B. Hold me tightly LOV. Nature Methods. 7: 595, 597. PMID 20676078 DOI: 10.1038/Nmeth0810-595 |
0.397 |
|
| 2010 |
Karginov AV, Ding F, Kota P, Dokholyan NV, Hahn KM. Engineered allosteric activation of kinases in living cells. Nature Biotechnology. 28: 743-7. PMID 20581846 DOI: 10.1038/Nbt.1639 |
0.622 |
|
| 2010 |
Wang X, He L, Wu YI, Hahn KM, Montell DJ. Light-mediated activation reveals a key role for Rac in collective guidance of cell movement in vivo. Nature Cell Biology. 12: 591-7. PMID 20473296 DOI: 10.1038/Ncb2061 |
0.449 |
|
| 2010 |
Samson T, Welch C, Monaghan-Benson E, Hahn KM, Burridge K. Endogenous RhoG is rapidly activated after epidermal growth factor stimulation through multiple guanine-nucleotide exchange factors. Molecular Biology of the Cell. 21: 1629-42. PMID 20237158 DOI: 10.1091/Mbc.E09-09-0809 |
0.72 |
|
| 2010 |
Hodgson L, Shen F, Hahn K. Biosensors for characterizing the dynamics of rho family GTPases in living cells. Current Protocols in Cell Biology / Editorial Board, Juan S. Bonifacino ... [Et Al.]. Unit 14.11.1-26. PMID 20235099 DOI: 10.1002/0471143030.Cb1411S46 |
0.334 |
|
| 2010 |
Yoo SK, Deng Q, Cavnar PJ, Wu YI, Hahn KM, Huttenlocher A. Differential regulation of protrusion and polarity by PI3K during neutrophil motility in live zebrafish. Developmental Cell. 18: 226-36. PMID 20159593 DOI: 10.1016/J.Devcel.2009.11.015 |
0.374 |
|
| 2010 |
Koivusalo M, Welch C, Hayashi H, Scott CC, Kim M, Alexander T, Touret N, Hahn KM, Grinstein S. Amiloride inhibits macropinocytosis by lowering submembranous pH and preventing Rac1 and Cdc42 signaling. The Journal of Cell Biology. 188: 547-63. PMID 20156964 DOI: 10.1083/Jcb.200908086 |
0.591 |
|
| 2010 |
Koivusalo M, Welch C, Hayashi H, Scott CC, Kim M, Alexander T, Touret N, Hahn KM, Grinstein S. Amiloride inhibits macropinocytosis by lowering submembranous pH and preventing Rac1 and Cdc42 signaling (Journal of Cell Biology (2010) 188, (547-563)) Journal of Cell Biology. 189: 385. DOI: 10.1083/Jcb.20090808620100331C |
0.607 |
|
| 2010 |
Gulyani A, Vitriol E, Gremyachinskiy D, Dewar BJ, Nguyen A, Graves LM, Kay BK, Hahn KM. High Throughput Screening of Biosensor Domains: Visualizing Dynamic Activation of Src Kinases in Live Cells Biophysical Journal. 98: 398a. DOI: 10.1016/J.Bpj.2009.12.2147 |
0.771 |
|
| 2009 |
Wu YI, Frey D, Lungu OI, Jaehrig A, Schlichting I, Kuhlman B, Hahn KM. A genetically encoded photoactivatable Rac controls the motility of living cells. Nature. 461: 104-8. PMID 19693014 DOI: 10.1038/Nature08241 |
0.828 |
|
| 2009 |
Machacek M, Hodgson L, Welch C, Elliott H, Pertz O, Nalbant P, Abell A, Johnson GL, Hahn KM, Danuser G. Coordination of Rho GTPase activities during cell protrusion. Nature. 461: 99-103. PMID 19693013 DOI: 10.1038/Nature08242 |
0.678 |
|
| 2009 |
Manukyan M, Nalbant P, Luxen S, Hahn KM, Knaus UG. RhoA GTPase activation by TLR2 and TLR3 ligands: connecting via Src to NF-kappa B. Journal of Immunology (Baltimore, Md. : 1950). 182: 3522-9. PMID 19265130 DOI: 10.4049/Jimmunol.0802280 |
0.32 |
|
| 2009 |
Su L, Pertz O, Mikawa M, Hahn K, Parsons SJ. p190RhoGAP negatively regulates Rho activity at the cleavage furrow of mitotic cells. Experimental Cell Research. 315: 1347-59. PMID 19254711 DOI: 10.1016/J.Yexcr.2009.02.014 |
0.321 |
|
| 2008 |
Jacobson K, Rajfur Z, Vitriol E, Hahn K. Chromophore-assisted laser inactivation in cell biology Trends in Cell Biology. 18: 443-450. PMID 18706812 DOI: 10.1016/J.Tcb.2008.07.001 |
0.773 |
|
| 2008 |
Sabouri-Ghomi M, Wu Y, Hahn K, Danuser G. Visualizing and quantifying adhesive signals. Current Opinion in Cell Biology. 20: 541-50. PMID 18586481 DOI: 10.1016/J.Ceb.2008.05.004 |
0.357 |
|
| 2008 |
Shen F, Hodgson L, Price JH, Hahn KM. Digital differential interference contrast autofocus for high-resolution oil-immersion microscopy. Cytometry. Part a : the Journal of the International Society For Analytical Cytology. 73: 658-66. PMID 18395817 DOI: 10.1002/Cyto.A.20558 |
0.338 |
|
| 2008 |
El-Sibai M, Pertz O, Pang H, Yip SC, Lorenz M, Symons M, Condeelis JS, Hahn KM, Backer JM. RhoA/ROCK-mediated switching between Cdc42- and Rac1-dependent protrusion in MTLn3 carcinoma cells. Experimental Cell Research. 314: 1540-52. PMID 18316075 DOI: 10.1016/J.Yexcr.2008.01.016 |
0.422 |
|
| 2008 |
Hodgson L, Pertz O, Hahn KM. Design and optimization of genetically encoded fluorescent biosensors: GTPase biosensors. Methods in Cell Biology. 85: 63-81. PMID 18155459 DOI: 10.1016/S0091-679X(08)85004-2 |
0.387 |
|
| 2008 |
Garrett SC, Hodgson L, Rybin A, Toutchkine A, Hahn KM, Lawrence DS, Bresnick AR. A biosensor of S100A4 metastasis factor activation: inhibitor screening and cellular activation dynamics. Biochemistry. 47: 986-96. PMID 18154362 DOI: 10.1021/Bi7021624 |
0.402 |
|
| 2008 |
Cai X, Lietha D, Ceccarelli DF, Karginov AV, Rajfur Z, Jacobson K, Hahn KM, Eck MJ, Schaller MD. Spatial and temporal regulation of focal adhesion kinase activity in living cells. Molecular and Cellular Biology. 28: 201-14. PMID 17967873 DOI: 10.1128/Mcb.01324-07 |
0.742 |
|
| 2008 |
Healy KD, Hodgson L, Kim TY, Shutes A, Maddileti S, Juliano RL, Hahn KM, Harden TK, Bang YJ, Der CJ. DLC-1 suppresses non-small cell lung cancer growth and invasion by RhoGAP-dependent and independent mechanisms. Molecular Carcinogenesis. 47: 326-37. PMID 17932950 DOI: 10.1002/Mc.20389 |
0.363 |
|
| 2007 |
Frantz C, Karydis A, Nalbant P, Hahn KM, Barber DL. Positive feedback between Cdc42 activity and H+ efflux by the Na-H exchanger NHE1 for polarity of migrating cells. The Journal of Cell Biology. 179: 403-10. PMID 17984318 DOI: 10.1083/Jcb.200704169 |
0.354 |
|
| 2007 |
El-Sibai M, Nalbant P, Pang H, Flinn RJ, Sarmiento C, Macaluso F, Cammer M, Condeelis JS, Hahn KM, Backer JM. Cdc42 is required for EGF-stimulated protrusion and motility in MTLn3 carcinoma cells. Journal of Cell Science. 120: 3465-74. PMID 17855387 DOI: 10.1242/Jcs.005942 |
0.372 |
|
| 2007 |
Hodgson L, Chan EW, Hahn KM, Yousaf MN. Combining surface chemistry with a FRET-based biosensor to study the dynamics of RhoA GTPase activation in cells on patterned substrates. Journal of the American Chemical Society. 129: 9264-5. PMID 17625860 DOI: 10.1021/Ja072900M |
0.375 |
|
| 2007 |
Toutchkine A, Nguyen DV, Hahn KM. Merocyanine dyes with improved photostability. Organic Letters. 9: 2775-7. PMID 17583344 DOI: 10.1021/Ol070780H |
0.306 |
|
| 2007 |
Birkenfeld J, Nalbant P, Bohl BP, Pertz O, Hahn KM, Bokoch GM. GEF-H1 modulates localized RhoA activation during cytokinesis under the control of mitotic kinases. Developmental Cell. 12: 699-712. PMID 17488622 DOI: 10.1016/J.Devcel.2007.03.014 |
0.346 |
|
| 2007 |
Birkenfeld J, Nalbant P, Bohl BP, Pertz O, Hahn KM, Bokoch GM. GEF-H1 Modulates Localized RhoA Activation during Cytokinesis under the Control of Mitotic Kinases (DOI:10.1016/j.devcel.2007.03.014) Developmental Cell. 12: 1007. DOI: 10.1016/J.Devcel.2007.05.013 |
0.332 |
|
| 2006 |
Wang YL, Hahn KM, Murphy RF, Horwitz AF. From imaging to understanding: Frontiers in Live Cell Imaging, Bethesda, MD, April 19-21, 2006. The Journal of Cell Biology. 174: 481-4. PMID 16908666 DOI: 10.1083/Jcb.200607097 |
0.336 |
|
| 2006 |
Van Keymeulen A, Wong K, Knight ZA, Govaerts C, Hahn KM, Shokat KM, Bourne HR. To stabilize neutrophil polarity, PIP3 and Cdc42 augment RhoA activity at the back as well as signals at the front. The Journal of Cell Biology. 174: 437-45. PMID 16864657 DOI: 10.1083/Jcb.200604113 |
0.386 |
|
| 2006 |
Shen F, Hodgson L, Rabinovich A, Pertz O, Hahn K, Price JH. Functional proteometrics for cell migration. Cytometry. Part a : the Journal of the International Society For Analytical Cytology. 69: 563-72. PMID 16752422 DOI: 10.1002/Cyto.A.20283 |
0.424 |
|
| 2006 |
Pertz O, Hodgson L, Klemke RL, Hahn KM. Spatiotemporal dynamics of RhoA activity in migrating cells. Nature. 440: 1069-72. PMID 16547516 DOI: 10.1038/Nature04665 |
0.411 |
|
| 2006 |
Wong K, Pertz O, Hahn K, Bourne H. Neutrophil polarization: spatiotemporal dynamics of RhoA activity support a self-organizing mechanism. Proceedings of the National Academy of Sciences of the United States of America. 103: 3639-44. PMID 16537448 DOI: 10.1073/Pnas.0600092103 |
0.382 |
|
| 2006 |
Nakamura K, Uhlik MT, Johnson NL, Hahn KM, Johnson GL. PB1 domain-dependent signaling complex is required for extracellular signal-regulated kinase 5 activation. Molecular and Cellular Biology. 26: 2065-79. PMID 16507987 DOI: 10.1128/Mcb.26.6.2065-2079.2006 |
0.373 |
|
| 2006 |
Euliss LE, Welch CM, Maynor BW, Rolland JP, Denison GM, Gratton SE, Park JY, Pandya AA, Enlow EL, Juliano RL, Hahn KM, DeSimone JM. Monodisperse nanocarriers: Novel fabrication of polymeric nanoparticles for bio-nanotechnology Proceedings of Spie - the International Society For Optical Engineering. 6153. DOI: 10.1117/12.656617 |
0.5 |
|
| 2005 |
Subauste MC, Nalbant P, Adamson ED, Hahn KM. Vinculin controls PTEN protein level by maintaining the interaction of the adherens junction protein beta-catenin with the scaffolding protein MAGI-2. The Journal of Biological Chemistry. 280: 5676-81. PMID 15579911 DOI: 10.1074/Jbc.M405561200 |
0.341 |
|
| 2004 |
Nalbant P, Hodgson L, Kraynov V, Toutchkine A, Hahn KM. Activation of endogenous Cdc42 visualized in living cells. Science (New York, N.Y.). 305: 1615-9. PMID 15361624 DOI: 10.1126/Science.1100367 |
0.466 |
|
| 2004 |
Subauste MC, Pertz O, Adamson ED, Turner CE, Junger S, Hahn KM. Vinculin modulation of paxillin-FAK interactions regulates ERK to control survival and motility. The Journal of Cell Biology. 165: 371-81. PMID 15138291 DOI: 10.1083/Jcb.200308011 |
0.417 |
|
| 2004 |
Pertz O, Hahn KM. Designing biosensors for Rho family proteins--deciphering the dynamics of Rho family GTPase activation in living cells. Journal of Cell Science. 117: 1313-8. PMID 15020671 DOI: 10.1242/Jcs.01117 |
0.454 |
|
| 2004 |
Tan X, Nalbant P, Toutchkine A, Hu D, Vorpagel ER, Hahn KM, Lu PP. Single-Molecule Study of Protein-Protein Interaction Dynamics in a Cell Signaling System Journal of Physical Chemistry B. 108: 737-744. DOI: 10.1021/Jp0306491 |
0.385 |
|
| 2003 |
Hahn K. Monitoring signaling processes in living cells using biosensors Science's Stke : Signal Transduction Knowledge Environment. 2003: tr5. PMID 14570979 DOI: 10.1126/Stke.2003.205.Tr5 |
0.4 |
|
| 2003 |
Toutchkine A, Kraynov V, Hahn K. Solvent-sensitive dyes to report protein conformational changes in living cells Journal of the American Chemical Society. 125: 4132-4145. PMID 12670235 DOI: 10.1021/Ja0290882 |
0.419 |
|
| 2003 |
Gaits F, Hahn K. Shedding light on cell signaling: interpretation of FRET biosensors. Science's Stke : Signal Transduction Knowledge Environment. 2003: PE3. PMID 12527820 DOI: 10.1126/Stke.2003.165.Pe3 |
0.45 |
|
| 2002 |
Price JH, Goodacre A, Hahn K, Hodgson L, Hunter EA, Krajewski S, Murphy RF, Rabinovich A, Reed JC, Heynen S. Advances in molecular labeling, high throughput imaging and machine intelligence portend powerful functional cellular biochemistry tools. Journal of Cellular Biochemistry. Supplement. 39: 194-210. PMID 12552619 DOI: 10.1002/Jcb.10448 |
0.331 |
|
| 2002 |
Gardiner EM, Pestonjamasp KN, Bohl BP, Chamberlain C, Hahn KM, Bokoch GM. Spatial and temporal analysis of Rac activation during live neutrophil chemotaxis. Current Biology : Cb. 12: 2029-34. PMID 12477392 DOI: 10.1016/S0960-9822(02)01334-9 |
0.429 |
|
| 2002 |
Tu SS, Wu WJ, Yang W, Nolbant P, Hahn K, Cerione RA. Antiapoptotic Cdc42 mutants are potent activators of cellular transformation. Biochemistry. 41: 12350-8. PMID 12369824 DOI: 10.1021/Bi026167H |
0.364 |
|
| 2002 |
Katsumi A, Milanini J, Kiosses WB, del Pozo MA, Kaunas R, Chien S, Hahn KM, Schwartz MA. Effects of cell tension on the small GTPase Rac. The Journal of Cell Biology. 158: 153-64. PMID 12105187 DOI: 10.1083/Jcb.200201105 |
0.373 |
|
| 2002 |
Hahn K, Toutchkine A. Live-cell fluorescent biosensors for activated signaling proteins Current Opinion in Cell Biology. 14: 167-172. PMID 11891115 DOI: 10.1016/S0955-0674(02)00313-7 |
0.457 |
|
| 2002 |
Del Pozo MA, Kiosses WB, Alderson NB, Meller N, Hahn KM, Schwartz MA. Integrins regulate GTP-Rac localized effector interactions through dissociation of Rho-GDI. Nature Cell Biology. 4: 232-9. PMID 11862216 DOI: 10.1038/Ncb759 |
0.375 |
|
| 2002 |
Frosst P, Guan T, Subauste C, Hahn K, Gerace L. Tpr is localized within the nuclear basket of the pore complex and has a role in nuclear protein export. The Journal of Cell Biology. 156: 617-30. PMID 11839768 DOI: 10.1083/Jcb.200106046 |
0.33 |
|
| 2001 |
Kiosses WB, Hahn KM, Giannelli G, Quaranta V. Characterization of morphological and cytoskeletal changes in MCF10A breast epithelial cells plated on laminin-5: comparison with breast cancer cell line MCF7. Cell Communication & Adhesion. 8: 29-44. PMID 11775027 DOI: 10.3109/15419060109080705 |
0.307 |
|
| 2001 |
Weiss TS, Chamberlain CE, Takeda T, Lin P, Hahn KM, Farquhar MG. Galpha i3 binding to calnuc on Golgi membranes in living cells monitored by fluorescence resonance energy transfer of green fluorescent protein fusion proteins. Proceedings of the National Academy of Sciences of the United States of America. 98: 14961-6. PMID 11752444 DOI: 10.1073/Pnas.261572098 |
0.365 |
|
| 2001 |
Subauste MC, List B, Guan X, Hahn KM, Lerner R, Gilula NB. A catalytic antibody produces fluorescent tracers of gap junction communication in living cells. The Journal of Biological Chemistry. 276: 49164-8. PMID 11606573 DOI: 10.1074/Jbc.M105700200 |
0.324 |
|
| 2000 |
Chamberlain C, Hahn KM. Watching proteins in the wild: fluorescence methods to study protein dynamics in living cells. Traffic (Copenhagen, Denmark). 1: 755-62. PMID 11208065 DOI: 10.1034/J.1600-0854.2000.011002.X |
0.412 |
|
| 2000 |
Chamberlain CE, Kraynov VS, Hahn KM. Imaging spatiotemporal dynamics of Rac activation in vivo with FLAIR. Methods in Enzymology. 325: 389-400. PMID 11036621 DOI: 10.1016/S0076-6879(00)25460-8 |
0.464 |
|
| 2000 |
Kraynov VS, Chamberlain C, Bokoch GM, Schwartz MA, Slabaugh S, Hahn KM. Localized Rac activation dynamics visualized in living cells. Science (New York, N.Y.). 290: 333-7. PMID 11030651 DOI: 10.1126/Science.290.5490.333 |
0.465 |
|
| 2000 |
Subauste MC, Von Herrath M, Benard V, Chamberlain CE, Chuang TH, Chu K, Bokoch GM, Hahn KM. Rho family proteins modulate rapid apoptosis induced by cytotoxic T lymphocytes and Fas. The Journal of Biological Chemistry. 275: 9725-33. PMID 10734125 DOI: 10.1074/Jbc.275.13.9725 |
0.316 |
|
| 2000 |
Bark SJ, Hahn KM. Fluorescent indicators of peptide cleavage in the trafficking compartments of living cells: peptides site-specifically labeled with two dyes. Methods (San Diego, Calif.). 20: 429-35. PMID 10720464 DOI: 10.1006/Meth.2000.0956 |
0.344 |
|
| 1999 |
Stupack DG, Li E, Silletti SA, Kehler JA, Geahlen RL, Hahn K, Nemerow GR, Cheresh DA. Matrix valency regulates integrin-mediated lymphoid adhesion via Syk kinase Journal of Cell Biology. 144: 777-787. PMID 10037798 DOI: 10.1083/Jcb.144.4.777 |
0.408 |
|
| 1998 |
Ben-Ami G, Ozeri V, Hanski E, Hofmann F, Aktories K, Hahn KM, Bokoch GM, Rosenshine I. Agents that inhibit Rho, Rac, and Cdc42 do not block formation of actin pedestals in HeLa cells infected with enteropathogenic Escherichia coli. Infection and Immunity. 66: 1755-8. PMID 9529109 DOI: 10.1128/Iai.66.4.1755-1758.1998 |
0.334 |
|
| 1997 |
Chuang TH, Hahn KM, Lee JD, Danley DE, Bokoch GM. The small GTPase Cdc42 initiates an apoptotic signaling pathway in Jurkat T lymphocytes. Molecular Biology of the Cell. 8: 1687-98. PMID 9307966 DOI: 10.1091/Mbc.8.9.1687 |
0.369 |
|
| 1996 |
Shelby RD, Hahn KM, Sullivan KF. Dynamic elastic behavior of alpha-satellite DNA domains visualized in situ in living human cells. The Journal of Cell Biology. 135: 545-57. PMID 8909532 DOI: 10.1083/Jcb.135.3.545 |
0.344 |
|
| 1996 |
Cornish VW, Hahn KM, Schultz PG. Site-specific protein modification using a ketone handle Journal of the American Chemical Society. 118: 8150-8151. DOI: 10.1021/Ja961216X |
0.303 |
|
| 1995 |
Southwick PL, Hahn KM, Chao J, Perry PL, Wagman AS, Wagner M, Waggoner AS. A long-wavelength biolabeling reagent based on the oxonol fluorophore. Journal of Fluorescence. 5: 231-5. PMID 24226669 DOI: 10.1007/Bf00727544 |
0.573 |
|
| 1995 |
Bark IC, Hahn KM, Ryabinin AE, Wilson MC. Differential expression of SNAP-25 protein isoforms during divergent vesicle fusion events of neural development. Proceedings of the National Academy of Sciences of the United States of America. 92: 1510-4. PMID 7878010 DOI: 10.1073/Pnas.92.5.1510 |
0.338 |
|
| 1994 |
Hahn K, DeBiasio R, Tishon A, Lewicki H, Gairin JE, LaRocca G, Taylor DL, Oldstone M. Antigen presentation and cytotoxic T lymphocyte killing studied in individual, living cells. Virology. 201: 330-40. PMID 8184542 DOI: 10.1006/Viro.1994.1298 |
0.319 |
|
| 1993 |
Hahn KM, Conrad PA, Chao JC, Taylor DL, Waggoner AS. A photocross-linking fluorescent indicator of mitochondrial membrane potential. The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. 41: 631-4. PMID 8450203 DOI: 10.1177/41.4.8450203 |
0.579 |
|
| 1992 |
Hahn K, DeBiasio R, Taylor DL. Patterns of elevated free calcium and calmodulin activation in living cells Nature. 359: 736-738. PMID 1436037 DOI: 10.1038/359736A0 |
0.341 |
|
| 1990 |
Hahn KM, Waggoner AS, Taylor DL. A calcium-sensitive fluorescent analog of calmodulin based on a novel calmodulin-binding fluorophore. The Journal of Biological Chemistry. 265: 20335-45. PMID 2173702 |
0.542 |
|
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